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Journal of Medicine and Pharmacy","Tạp chí Y Dược học Cần Thơ",{"EN":487,"VI":488},"\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">04\u002F10\u002F2015 Ministry of Information and Communications allowed Can Tho journal of medicine and pharmacy to operate (102 \u002FGP-BTTTT)\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">07\u002F16\u002F2015 Can Tho journal of medicine and pharmacy is internationally recognized: ISSN 2354-1210\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">In 2016, The journal has been included in the list of medical science journals by The State Council for professorship which is awarded a work score of 0-0.5 points for a published article.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Can Tho Journal of Medicine and Pharmacy welcome original works that haven’t been submitted or published in other medical journals. Posts must contain content related to one of the journal’s categories.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The content published\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The journal is divided into 3 categories:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Scientific research article: are valuable scientific works, which have been researched and accepted.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Overview of medicine, biology and pharmacy: serving the objective of continuing training in the fields of medicine, biology and pharmacy; to systematize classical and modern knowledge.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Update information on new knowledge about medicine, biology, pharmacy in the country and in the world.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Scope\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Publication and introduction of scientific research in the fields:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Medicine (internal medicine, surgery, pediatrics, obstetrics and gynecology, odonto-stomatology, laboratory, oncology, traditional medicine, nursing).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Biology (genetics, biotechnology).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Pharmacology (pharmaceutics, drug quality analysis-control, synthetic pharmaceutical chemistry, biochemistry, pharmacognosy, botany, clinical pharmacy).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- To enhance the quality of undergraduate, postgraduate education, scientifically researching and meet the necessary treatment in hospital.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Introducing the updated domestic and oversea information about science technology to promote scientific research and exchanging technology in local, other universities.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Exchanging pharmaceutical and medical information for social health developing in the Mekong Delta and Vietnam.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The object\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Postgraduate students, student of Can Tho University of Medicine and Pharmacy, scientists from schools, research institutes, hospitals, health centers, pharmaceutical companies of the Mekong Delta; other provinces and regions in Vietnam and other country.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Address\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Headquarters of Can Tho Journal of Medicine and Pharmacy, located Scientific Research and International Cooperation Office: 179 Nguyen Van Cu Street, An Khanh Ward, Ninh Kieu District, Can Tho City, Vietnam.\u003C\u002Fspan>\u003C\u002Fp>","\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Ngày 16\u002F7\u002F2015, Tạp chí Y Dược học Cần Thơ được cấp chỉ số quốc tế: ISSN 2354-1210.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 4\u002F2016, Tạp chí đã được Hội đồng Giáo sư ngành Y đưa vào danh sách các tạp chí khoa học Y học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Năm 2020 Tạp chí Y Dược học Cần Thơ đã được phê duyệt vào danh mục của các Hội đồng Giáo sư ngành Dược học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ ra 12 số\u002Fnăm, 180-200 trang\u002Fsố.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 12\u002F2022 Tạp chí Y Dược học Cần Thơ là thành viên của hệ thống Crossref và từ tháng 01\u002F2023 tạp chí thực hiện bình duyệt online kín 2 chiều nhằm tăng tính minh bạch, tin cậy của các công trình nghiên cứu khoa học và đảm bảo tốt nhất chất lượng khoa học của bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ, mục đích và phạm vi của tạp chí\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ và mục đích hoạt động của tạp chí: xuất bản nhằm mục đích phổ biến kết quả từ các đề tài nghiên cứu khoa học; giao lưu trao đổi khoa học, chia sẻ kinh nghiệm, học tập, đồng thời cập nhật thông tin khoa học mới trong các lĩnh vực y, sinh, dược học trong và ngoài nước.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phạm vi của tạp chí: Tạp chí xuất bản được chia thành 3 chuyên mục: (i) Bài báo nghiên cứu khoa học là kết quả công trình nghiên cứu khoa học có giá trị đã được triển khai nghiên cứu, (ii) Bài tổng quan y, sinh, dược học: phục vụ mục tiêu đào tạo liên tục trong lĩnh vực y, sinh, dược học; nhằm hệ thống hóa những kiến thức kinh điển và hiện đại; (iii) Thông tin cập nhật kiến thức mới về y, sinh, dược học trong nước và trên thế giới.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Chính sách truy cập mở\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ áp dụng chính sách truy cập mở đối với các bài báo đã xuất bản đến với độc giả, nhằm mở rộng cơ hội tiếp cận các kết quả nghiên cứu chất lượng cao và tăng cường trao đổi kiến thức. Tạp chí đăng tải trực tuyến (miễn phí) toàn văn các bài báo được công bố trên website của Tạp chí (https:\u002F\u002Ftapchi.ctump.edu.vn).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đạo đức xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ cam kết tuân thủ đạo đức xuất bản phù hợp với các hướng dẫn và tiêu chuẩn của the Committee on Publication Ethics (COPE), tuân thủ các nguyên tắc của COPE’s Core Practices, Best Practices Guidelines for Journal Editors và Guidelines on Good Publication Practices.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Bản thảo bài báo chỉ được chấp nhận khi được tác giả chịu trách nhiệm chính cam kết các nội dung sau: Các nội dung của bản thảo chưa được đăng tải toàn bộ hoặc một phần ở các tạp chí khác; Tất cả các tác giả đều có đóng góp một cách đáng kể vào quá trình nghiên cứu hoặc chuẩn bị bản thảo và cùng chịu trách nhiệm về các nội dung của bản thảo; Tuân thủ các biện pháp đảm bảo đạo đức nghiên cứu (ví dụ thỏa thuận đồng ý tham gia nghiên cứu).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Cam kết bảo mật\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí cam kết thực hiện và tuân thủ các quy định của luật và các văn bản hướng dẫn liên quan đến bảo mật thông tin cá nhân trên không gian mạng. Các thông tin mà người dùng (tác giả, độc giả, biên tập viên, người phản biện) nhập vào các biểu mẫu trên Hệ thống Quản lý xuất bản trực tuyến của tạp chí chỉ được sử dụng vào các mục đích đã được tuyên bố rõ ràng và sẽ không được cung cấp cho bất kỳ bên thứ ba nào khác, hay dùng vào bất kỳ mục đích nào khác.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phí gửi bài\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng bài: 1.000.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng nhanh: 1.500.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với tác giả là cán bộ viên chức thuộc Trường Đại học Y Dược Cần Thơ thì được hỗ trợ 50% lệ phí gửi đăng bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với sinh viên thực hiện đề tài nghiên cứu khoa học cấp trường được hỗ trợ 100% lệ phí đăng bài ( Tác giả gửi đính kèm “ Quyết định về việc giao tổ chức thực hiện đề tài nghiên cứu khoa học cấp Trường của sinh viên”).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Hình thức nộp lệ phí:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Tiền mặt:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Nộp trực tiếp tại Phòng Tài chính - Kế toán, Trường Đại học Y Dược Cần Thơ, số 179 Nguyễn Văn Cừ, P. An Khánh, Q. Ninh Kiều, thành phố Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Chuyển khoản:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tên Tài khoản: Trường ĐHYD Cần Thơ, Số TK: 0111000115668, tại ngân hàng Vietcombank chi nhánh Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Thời gian: Áp dụng từ ngày 01\u002F02\u002F2023.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">* Phí gửi bài không được hoàn trả khi bài viết bị từ chối hoặc tác giả xin rút bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Quy trình phản biện bài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ thực hiện quy trình phản biện kín hai chiều nghiêm ngặt. Danh tính của những người phản biện không được tiết lộ cho các tác giả và ngược lại. Quy trình thẩm định bài báo đăng gồm các bước sau:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tiếp nhận bản thảo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tác giả liên hệ gửi bản thảo đến Tạp chí qua hệ thống trực tuyến tại website: https:\u002F\u002Ftapchi.ctump.edu.vn. Hướng dẫn về cách đăng ký, gửi bài và chuẩn bị bản thảo được cung cấp trên website của Tạp chí.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sàng lọc sơ bộ\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sau khi Tòa soạn nhận được bài báo của tác giả, Ban Thư ký sẽ tiến hành kiểm tra sơ bộ bài báo (các yêu cầu về nội dung và hình thức). Những bài báo không đúng quy cách hoặc có nội dung không phù hợp hoặc vi phạm bản quyền sẽ bị từ chối (Ban Thư ký thông báo phản hồi đến tác giả trong vòng 1 tuần). Những bài báo đủ điều kiện, được Ban Thư ký tòa soạn chuyển đến Ban Biên tập có cùng chuyên môn với nội dung bài báo để đề xuất người phản biện. Thời gian kể từ khi Ban Biên tập nhận bài báo đến khi đề xuất người phản biện bài báo chậm nhất là 5 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Vòng phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký gửi bài và yêu cầu phản biện đến 02 phản biện độc lập.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Các phản biện gởi nhận xét cho Ban Thư ký. Thời gian từ khi gửi bài cho phản biện đến khi nhận ý kiến của phản biện tối đa là 20 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xử ký kết quả phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Nếu ý kiến đồng ý cho đăng và không cần chỉnh sửa, Ban Thư ký tiếp tục đăng bài theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Nếu ý kiến đồng ý đăng và cần chỉnh sửa, Ban Thư ký sẽ thông tin đến tác giả chỉnh sửa theo yêu cầu của người phản biện. Thời gian chỉnh sửa và gửi lại kéo dài không quá 2 tuần, từ khi tác giả bài báo nhận được thông tin (Quá trình này có thể lặp lại tối đa 2 lần\u002F1 bài báo). Khi có sự thống nhất, đồng ý của người phản biện; bài báo được tiếp tục đăng theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Những bài báo có chất lượng không đạt yêu cầu, cả 2 phản biện không đồng ý cho đăng sẽ bị Tòa soạn từ chối đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký tổng hợp các bản thảo đã được tác giả hoàn thiện sau thẩm định trình Ban Biên tập xem xét, Tổng Biên tập phê duyệt, quyết định bài đăng theo các tiêu chí: sự phù hợp nội dung với tôn chỉ và mục đích, thể loại bài viết (ưu tiên các bài có bài có nghiên cứu chuyên sâu, hàm lượng khoa học cao), đóng góp mới bài báo, bài báo được ưu tiên đăng trong số gần nhất của Tạp chí theo thứ tự: tính thời sự, chất lượng bài báo và thời gian gửi bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Ban Biên tập và Ban Thư ký biên tập bản thảo, chế bản, đọc rà soát lỗi. Thời gian hoàn thành từ 10-15 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Ban Thư ký có trách nhiệm thông báo cho tác giả bài báo (bằng e-mail) về tình hình phê duyệt bài báo, thời gian, số kỳ, tập xuất bản bài báo theo qui định.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">4. Danh sách bài báo theo số Tạp chí được in ấn và phát hành trong năm định kỳ được công bố chính thức trên website: https:\u002F\u002Ftapchi.ctump.edu.vn\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>",{"VOID":490},"wcQ1uqwAAAAJ","2023-05-30T08:17:21.868+00:00",[],[494],{"id":495,"createTime":28,"updateTime":28,"relativeEntities":496,"slug":28,"properties":497,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":507,"parentIds":508,"statistic":28},"6413896b-eca9-442b-a73f-182a58a0ce40",[],{"title":498,"address":501,"country":504,"abbreviation":505},{"EN":499,"VI":500},"Can Tho University of Medicine and Pharmacy","Trường Đại học Y Dược Cần Thơ",{"EN":502,"VI":503},"No 179, Nguyen Van Cu street, An Khanh ward, Ninh Kieu district, Can Tho city, Vietnam","Số 179, đường Nguyễn Văn Cừ, phường An Khánh, quận Ninh Kiều, thành phố Cần Thơ, Việt Nam",{"VOID":15},{"VOID":506},"ctump","http:\u002F\u002Fwww.ctump.edu.vn\u002F",[],[],"https:\u002F\u002Ftapchi.ctump.edu.vn\u002Findex.php\u002Fctump",{"impactFactor":32,"impactFactorByYear":512,"i10Index":32,"i10IndexLast5Year":32,"totalPublication":514,"totalPublicationByYear":515,"totalCitation":520,"totalCitationByYear":521,"totalCitationPerPublication":108,"totalCitationPerPublicationByYear":523,"hindexLast5Year":45,"hindex":45},{"2022":513,"2023":111,"2024":106},0.01,1556,{"2020":47,"2021":516,"2022":517,"2023":518,"2024":519,"2025":122},57,306,801,358,161,{"2021":146,"2022":280,"2023":522},99,{"2021":524,"2022":318,"2023":104},0.23,{"impactFactor":28,"impactFactorByYear":28,"i10Index":123,"i10IndexLast5Year":123,"totalPublication":526,"totalPublicationByYear":527,"totalCitation":526,"totalCitationByYear":528,"totalCitationPerPublication":40,"totalCitationPerPublicationByYear":531,"hindexLast5Year":49,"hindex":49},476,{"0":205,"2019":123,"2021":139,"2022":459,"2023":451,"2024":357,"2025":49,"2026":48},{"2021":42,"2022":123,"2023":161,"2024":529,"2025":360,"2026":530},136,83,{"2021":105,"2022":513,"2023":532,"2024":127,"2025":533,"2026":534},0.62,25.43,13.83,{"id":536,"createTime":537,"updateTime":382,"relativeEntities":538,"slug":539,"properties":540,"entityType":25,"verifyStatus":26,"verifyTime":28,"verifyNote":28,"languages":552,"translateLanguages":28,"viewCount":133,"subjectFields":553,"manageAffiliations":554,"indexDatabases":555,"url":556,"thumbnailPath":557,"statistic":558,"gsStatistic":594,"type":55,"analyzePriority":28},"6984a56a-db70-403b-9cc4-4013e1ceaffa","2023-05-09T06:47:40.346+00:00",[],"T%E1%BA%A1p%20ch%C3%AD%20Nghi%C3%AAn%20c%E1%BB%A9u%20n%C6%B0%E1%BB%9Bc%20ngo%C3%A0i",{"country":541,"issn":542,"title":544,"introduce":547,"gsId":550},{"VOID":15},{"VOID":543},"25252445",{"EN":545,"VI":546},"VNU Journal of Foreign Studies","Tạp chí Nghiên cứu nước ngoài",{"EN":548,"VI":549},"{\"ops\":[{\"insert\":\"\\n\\nThe \\n\"},{\"attributes\":{\"italic\":true},\"insert\":\"VNU Journal of Science\"},{\"insert\":\"\\n was established in 1985 for the publication of national and international research papers in all fields of natural sciences and technology, social sciences and humanities. 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The purpose of this study was to develop a radioprobe that targets one of the most widely used reporter genes, the bacterial lacZ gene. We synthesised and purified radioiodine-labelled phenylethyl-β-d-thiogalactopyranoside (PETG), a competitive inhibitor specific against Escherichia coli β-galactosidase. We showed that [125I]iodo-PETG specifically binds to β-galactosidase as verified by column chromatography and polyacrylamide gel electrophoresis after incubation of radiotracer with the protein. We also showed through enzyme kinetic studies that iodo-PETG retains inhibitory action against β-galactosidase activity. COS-7 cells infected with a recombinant adenovirus expressing the lacZ gene had viral titre-dependent enhancements in [125I]iodo-PETG uptake (r\n                        2=0.897; P=0.001), which reached up to 642.5%±16.7% of control levels (P\u003C0.00001). Moreover, the level of uptake was highly correlated to luminescent measurements of β-galactosidase activity (r\n                        2=0.878; P\u003C0.0001). These results confirm that radioiodine-labelled PETG specifically targets β-galactosidase and that its uptake rates faithfully reflect levels of expression of the lacZ reporter gene. Further investigations were performed in nude mice bearing human neuroblastoma tumours transferred with the lacZ gene. Compared with control tumours, lacZ-expressing tumours were slightly better visualised on [123I]iodo-PETG images and had a modest increase in tumour to muscle count ratio (2.6±0.2 vs 1.9±0.1, P\u003C0.05). The present results provide proof-of-principle for the potential of radiolabelled inhibitors as promising radiotracers to monitor lacZ gene expression levels. Future modifications to improve cell permeability should enhance in vivo contrast levels and may allow the use of radiolabelled β-galactosidase inhibitors for non-invasive monitoring of lacZ gene expression.",{"EN":959},"Targeting of lacZ reporter gene expression with radioiodine-labelled phenylethyl-β-d-thiogalactopyranoside",{"VOID":961},"Alam J, Cook JL. Reporter genes: application to the study of mammalian gene transcription. Anal Biochem 1990; 188:245–254.\nHuard J, Akkaraju G, Watkins SC, Pike-Cavalcoli M, Glorioso JC. LacZ gene transfer to skeletal muscle using a replication-defective herpes simplex virus type 1 mutant vector. Hum Gene Ther 1997; 8:439–452.\nRay P, Bauer E, Iyer M, Barrio JR, Satyamurthy N, Phelps ME, Herschman HR, Gambhir SS. Monitoring gene therapy with reporter gene imaging. Semin Nucl Med 2001; 31:312–320.\nJacobs A, Tjuvajev JG, Dubrovin M, Akhurst T, Balatoni J, Beattie B, Joshi R, Finn R, Larson SM, Herrlinger U, Pechan PA, Chiocca EA, Breakefield XO, Blasberg RG. Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic herpes simplex virus type 1 mutant vectors in vivo. Cancer Res 2001; 61:2983–2995.\nGambhir SS, Barrio JR, Phelps ME, Iyer M, Namavari M, Satyamurthy N, Wu L, Green LA, Bauer E, MacLaren DC, Nguyen K, Berk AJ, Cherry SR, Herschman HR. Imaging adenoviral-directed reporter gene expression in living animals with positron emission tomography. Proc Natl Acad Sci U S A 1999; 96:2333–2338.\nLiang Q, Satyamurthy N, Barrio JR, Toyokuni T, Phelps MP, Gambhir SS, Herschman HR. Noninvasive, quantitative imaging in living animals of a mutant dopamine D2 receptor reporter gene in which ligand binding is uncoupled from signal transduction. Gene Ther 2001; 8:1490–1498.\nKundra V, Mannting F, Jones AG, Kassis AI. Noninvasive monitoring of somatostatin receptor type 2 chimeric gene transfer. J Nucl Med 2002; 43:406–412.\nChoi JH, Choe YS, Lee KH, Choi Y, Kim SE, Kim BT. Synthesis of radioiodine-labeled 2-phenylethyl 1-thio-beta-d-galactopyranoside for imaging of LacZ gene expression. Carbohydr Res 2003; 338:29–34.\nLee SY, Choe YS, Kim DH, Park BN, Kim SE, Choi Y, Lee KH, Lee J, Kim BT. A simple and efficient in vitro method for metabolism studies of radiotracers. Nucl Med Biol 2001; 28:391–395.\nFukumoto S, Hsieh CM, Maemura K, Layne MD, Yet SF, Lee KH, Matsui T, Rosenzweig A, Taylor WG, Rubin JS, Perrella MA, Lee ME. Akt participation in the Wnt signaling pathway through Dishevelled. J Biol Chem 2001; 276:17479–17483.\nFiering SN, Roederer M, Nolan GP, Micklem DR, Parks DR, Herzenberg LA. Improved FACS-galactosidase: flow cytometric analysis and sorting of viable eukaryotic cells expressing reporter gene constructs. Cytometry 1991; 12:291–301.\nHadd AG, Raymond DE, Halliwell JW, Jacobson SC, Ramsey JM. Microchip device for performing enzyme assays. Anal Chem 1997; 69:3407–3412.\nJongkind JF, Verkerk A, Sernitz M. Detection of acid-β-galactosidase activity in viable human fiboblasts by flow cytometry. Cytometry 1986; 7:463–466.\nWeiss DJ, Liggitt D, Clark JG. Histochemical discrimination of endogenous mammalian beta-galactosidase activity from that resulting from lac-Z gene expression. Histochem J 1999; 31:231–236.\nPlagemann PG, Wohlhueter RM, Graff J, Erbe J, Wilkie P. Broad specificity hexose transport system with differential mobility of loaded and empty carrier, but directional symmetry, is common property of mammalian cell lines. J Biol Chem 1981; 256:2835–2842.\nIshiwata K, Yamaguchi K, Kameyama M, Fukuda H, Tada M, Matsuzawa T, Muraishi K, Itoh J, Kawashima K, Takahashi T. 2-Deoxy-2-[18F]fluoro-d-galactose as an in vivo tracer for imaging galactose metabolism in tumors with positron emission tomography. 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diagnosis of osteomyelitis is a challenge for diagnostic imaging. Nuclear medicine procedures including white blood cell imaging have been successfully used for the identification of bone infections. This multinational, phase III clinical study in 22 European centres was undertaken to compare anti-granulocyte imaging using the murine IgG antibody besilesomab (Scintimun®) with 99mTc-labelled white blood cells in patients with peripheral osteomyelitis. A total of 119 patients with suspected osteomyelitis of the peripheral skeleton received 99mTc-besilesomab and 99mTc-hexamethylpropyleneamine oxime (HMPAO)-labelled white blood cells (WBCs) in random order 2–4 days apart. Planar images were acquired at 4 and 24 h after injection. All scintigraphic images were interpreted in an off-site blinded read by three experienced physicians specialized in nuclear medicine, followed by a fourth blinded reader for adjudication. In addition, clinical follow-up information was collected and a final diagnosis was provided by the investigators and an independent truth panel. Safety data including levels of human anti-mouse antibodies (HAMA) and vital signs were recorded. The agreement in diagnosis across all three readers between Scintimun® and 99mTc-HMPAO-labelled WBCs was 0.83 (lower limit of the 95% confidence interval 0.8). Using the final diagnosis of the local investigator as a reference, Scintimun® had higher sensitivity than 99mTc-HMPAO-labelled WBCs (74.8 vs 59.0%) at slightly lower specificity (71.8 vs 79.5%, respectively). All parameters related to patient safety (laboratory data, vital signs) did not provide evidence of an elevated risk associated with the use of Scintimun® except for two cases of transient hypotension. HAMA were detected in 16 of 116 patients after scan (13.8%). Scintimun® imaging is accurate, efficacious and safe in the diagnosis of peripheral bone infections and provides comparable information to 99mTc-HMPAO-labelled WBCs.",{"EN":1115},"99mTc-besilesomab (Scintimun®) in peripheral osteomyelitis: comparison with 99mTc-labelled white blood cells",{"VOID":1117},"Concia E, Prandini N, Massari L, Ghisellini F, Consoli V, Menichetti F, et al. Osteomyelitis: clinical update for practical guidelines. Nucl Med Commun 2006;27:645–60.\nLove C, Marwin SE, Palestro CJ. Nuclear medicine and the infected joint replacement. Semin Nucl Med 2009;39:66–78.\nChatha DS, Cunningham PM, Schweitzer ME. MR imaging of the diabetic foot: diagnostic challenges. Radiol Clin North Am 2005;43:747–59. ix.\nGnanasegaran G, Chicklore S, Vijayanathan S, O’Doherty MJ, Fogelman I. Diabetes and bone: advantages and limitations of radiological, radionuclide and hybrid techniques in the assessment of diabetic foot. Minerva Endocrinol 2009;34:237–54.\nRozzanigo U, Tagliani A, Vittorini E, Pacchioni R, Brivio LR, Caudana R. Role of magnetic resonance imaging in the evaluation of diabetic foot with suspected osteomyelitis. Radiol Med 2009;114:121–32.\nRojas-Burke J. Health officials reacting to infection mishaps. J Nucl Med 1992;33:13N–4N. 27N.\nde Vries EF, Roca M, Jamar F, Israel O, Signore A. Guidelines for the labelling of leucocytes with (99m)Tc-HMPAO. Inflammation\u002Finfection Taskgroup of the European Association of Nuclear Medicine. Eur J Nucl Med Mol Imaging 2010;37:842–8.\nSchwenke C, Busse R. Analysis of differences in proportions from clustered data with multiple measurements in diagnostic studies. Methods Inf Med 2007;46:548–52.\nTermaat MF, Raijmakers PG, Scholten HJ, Bakker FC, Patka P, Haarman HJ. The accuracy of diagnostic imaging for the assessment of chronic osteomyelitis: a systematic review and meta-analysis. J Bone Joint Surg Am 2005;87:2464–71.\nSteinsträsser A, Berberich R, Kuhlmann L, Zabori S, Schwarz A. Binding of the monoclonal antibody BW 250\u002F183 to human granulocytes. Nuklearmedizin 1992;31:57–63.\nBosslet K, Steinsträsser A, Schwarz A, Harthus HP, Lüben G, Kuhlmann L, et al. Quantitative considerations supporting the irrelevance of circulating serum CEA for the immunoscintigraphic visualization of CEA expressing carcinomas. Eur J Nucl Med 1988;14:523–8.\nMorguet AJ, Munz DL, Ivancević V, Werner GS, Sandrock D, Bökemeier M, et al. Immunoscintigraphy using technetium-99m-labeled anti-NCA-95 antigranulocyte antibodies as an adjunct to echocardiography in subacute infective endocarditis. J Am Coll Cardiol 1994;23:1171–8.\nMorguet AJ, Munz DL, Ivancević V, Werner GS, Kreuzer H. The clinical importance of scintigraphy with the murine monoclonal antigranulocyte antibody BW 250\u002F183 for the diagnosis of prosthesis-related endocarditis. Dtsch Med Wochenschr 1995;120:861–6.\nSegarra I, Roca M, Baliellas C, Vilar L, Ricart Y, Mora J, et al. Granulocyte-specific monoclonal antibody technetium-99m-BW 250\u002F183 and indium-111 oxine-labelled leucocyte scintigraphy in inflammatory bowel disease. Eur J Nucl Med 1991;18:715–9.\nPapos M, Nagy F, Narai G, Rajtar M, Szantai G, Lang J, et al. Anti-granulocyte immunoscintigraphy and [99mTc]hexamethylpropyleneamine-oxime-labeled leukocyte scintigraphy in inflammatory bowel disease. Dig Dis Sci 1996;41:412–20.\nAlmers S, Granerus G, Franzén L, Ström M. Technetium-99m scintigraphy: more accurate assessment of ulcerative colitis with exametazime-labelled leucocytes than with antigranulocyte antibodies. Eur J Nucl Med 1996;23:247–55.\nTarján Z, Tóth G, Györke T, Mester A, Karlinger K, Makó EK. Ultrasound in Crohn’s disease of the small bowel. Eur J Radiol 2000;35:176–82.\nPeltier P, Potel G, Lovat E, Baron D, Chatal JF. Detection of lung and bone infection with anti-granulocyte monoclonal antibody BW 250\u002F183 radiolabelled with 99Tcm. Nucl Med Commun 1993;14:766–74.\nKroiss A, Sporn P, Auinger C, Redl E, Böck F, Dinstl K, et al. Immunoscintigraphy for detection of inflammatory perioperative foci. Acta Med Austriaca 1993;20:45–9.\nBecker W, Dölkemeyer U, Gramatzki M, Schneider MU, Scheele J, Wolf F. Use of immunoscintigraphy in the diagnosis of fever of unknown origin. Eur J Nucl Med 1993;20:1078–83.\nMeller J, Ivancevic V, Conrad M, Gratz S, Munz DL, Becker W. Clinical value of immunoscintigraphy in patients with fever of unknown origin. J Nucl Med 1998;39:1248–53.\nGratz S, Behr TM, Herrmann A, Meller J, Conrad M, Zappel H, et al. Immunoscintigraphy (BW 250\u002F183) in neonates and infants with fever of unknown origin. Nucl Med Commun 1998;19:1037–45.\nGraute V, Feist M, Lehner S, Haug A, Müller PE, Bartenstein P, et al. Detection of low-grade prosthetic joint infections using (99m)Tc-antigranulocyte SPECT\u002FCT: initial clinical results. Eur J Nucl Med Mol Imaging 2010;37:1751–9.\nGuhlmann A, Brecht-Krauss D, Suger G, Glatting G, Kotzerke J, Kinzl L, et al. Fluorine-18-FDG PET and technetium-99m antigranulocyte antibody scintigraphy in chronic osteomyelitis. J Nucl Med 1998;39:2145–52.\nKaim A, Maurer T, Ochsner P, Jundt G, Kirsch E, Mueller-Brand J. Chronic complicated osteomyelitis of the appendicular skeleton: diagnosis with technetium-99m labelled monoclonal antigranulocyte antibody-immunoscintigraphy. Eur J Nucl Med 1997;24:732–8.\nKroiss A, Böck F, Perneczky G, Auinger C, Weidlich G, Kleinpeter G, et al. Immunoscintigraphy for the detection of inflammation foci in bone and joint diseases. Wien Klin Wochenschr 1990;102:713–7.\nHotze AL, Briele B, Overbeck B, Kropp J, Gruenwald F, Mekkawy MA, et al. Technetium-99m-labeled anti-granulocyte antibodies in suspected bone infections. J Nucl Med 1992;33:526–31.\nReuland P, Winker KH, Heuchert T, Ruck P, Müller-Schauenburg W, Weller S, et al. Detection of infection in postoperative orthopedic patients with technetium-99m-labeled monoclonal antibodies against granulocytes. J Nucl Med 1991;32:2209–14.\nSteinsträsser A, Oberhausen E. Granulocyte labelling kit BW 250\u002F183–results of the European multicenter trial. Nuklearmedizin 1996;35:1–11.\nBoubaker A, Delaloye AB, Blanc CH, Dutoit M, Leyvraz PF, Delaloye B. Immunoscintigraphy with antigranulocyte monoclonal antibodies for the diagnosis of septic loosening of hip prostheses. Eur J Nucl Med 1995;22:139–47.\nBecker W, Bair J, Behr T, Repp R, Streckenbach H, Beck H, et al. Detection of soft-tissue infections and osteomyelitis using a technetium-99m-labeled anti-granulocyte monoclonal antibody fragment. 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Baseline LV dyssynchrony assessed with standard deviation (SD) of time-to-peak systolic velocity of 12 LV segments (Ts-SD) with TDI has proven to be a powerful predictor of response to CRT. Information on LV dyssynchrony can also be provided by GMPS with phase analysis of regional LV maximal count changes throughout the cardiac cycle. Forty heart failure patients, referred for evaluation of potential eligibility for CRT, underwent both 3D echocardiography, with tri-plane TDI, and resting GMPS. From tri-plane TDI, Ts-SD was used as a validated parameter of LV dyssynchrony and compared with different indices (histogram bandwidth, phase SD, histogram skewness and kurtosis) derived from phase analysis of GMPS. Histogram bandwidth and phase SD showed good correlation with Ts-SD (r=0.77 and r=0.74, p\u003C0.0001, respectively). Patients with substantial LV dyssynchrony assessed with tri-plane TDI (Ts-SD ≥33 ms) had also significantly higher values of histogram bandwidth and phase SD. The results of this study support the use of phase analysis by GMPS to evaluate LV dyssynchrony. Histogram bandwidth and phase SD showed the best correlation with Ts-SD assessed with tri-plane TDI and appeared the most optimal variables for assessment of LV dyssynchrony with GMPS.",{"EN":1470},"Left ventricular dyssynchrony assessed by two three-dimensional imaging modalities: phase analysis of gated myocardial perfusion SPECT and tri-plane tissue Doppler imaging",{"VOID":1472},"Freemantle N, Tharmanathan P, Calvert MJ, Abraham WT, Ghosh J, Cleland JG. Cardiac resynchronisation for patients with heart failure due to left ventricular systolic dysfunction-a systematic review and meta-analysis. Eur J Heart Fail 2006;8:433–40.\nAbraham WT, Fisher WG, Smith AL, Delurgio DB, Leon AR, Loh E, et al. Cardiac resynchronization in chronic heart failure. N Engl J Med 2002;346:1845–53.\nBax JJ, Bleeker GB, Marwick TH, Molhoek SG, Boersma E, Steendijk P, et al. Left ventricular dyssynchrony predicts response and prognosis after cardiac resynchronization therapy. J Am Coll Cardiol 2004;44:1834–40.\nSogaard P, Egeblad H, Kim WY, Jensen HK, Pedersen AK, Kristensen BO, et al. Tissue Doppler imaging predicts improved systolic performance and reversed left ventricular remodeling during long-term cardiac resynchronization therapy. J Am Coll Cardiol 2002;40:723–30.\nNotabartolo D, Merlino JD, Smith AL, Delurgio DB, Vera FV, Easley KA, et al. Usefulness of the peak velocity difference by tissue Doppler imaging technique as an effective predictor of response to cardiac resynchronization therapy. Am J Cardiol 2004;94:817–20.\nYu CM, Chau E, Sanderson JE, Fan K, Tang MO, Fung WH, et al. Tissue Doppler echocardiographic evidence of reverse remodeling and improved synchronicity by simultaneously delaying regional contraction after biventricular pacing therapy in heart failure. Circulation 2002;105:438–45.\nYu CM, Zhang Q, Fung JW, Chan HC, Chan YS, Yip GW, et al. A novel tool to assess systolic asynchrony and identify responders of cardiac resynchronization therapy by tissue synchronization imaging. J Am Coll Cardiol 2005;45:677–84.\nYu CM, Fung WH, Lin H, Zhang Q, Sanderson JE, Lau CP. Predictors of left ventricular reverse remodeling after cardiac resynchronization therapy for heart failure secondary to idiopathic dilated or ischemic cardiomyopathy. Am J Cardiol 2003;91:684–8.\nChen J, Garcia EV, Folks RD, Cooke CD, Faber TL, Tauxe EL, et al. Onset of left ventricular mechanical contraction as determined by phase analysis of ECG-gated myocardial perfusion SPECT imaging: development of a diagnostic tool for assessment of cardiac mechanical dyssynchrony. J Nucl Cardiol 2005;12:687–95.\nHenneman MM, Chen J, Ypenburg C, Dibbets P, Bleeker GB, Boersma E, et al. Phase analysis of gated myocardial perfusion SPECT compared to tissue Doppler imaging for the assessment of left ventricular dyssynchrony. J Am Coll Cardiol 2007;49:1708–14.\nLevine MG, McGill CC, Ahlberg AW, White MP, Giri S, Shareef B, et al. Functional assessment with electrocardiographic gated single-photon emission computed tomography improves the ability of technetium-99m sestamibi myocardial perfusion imaging to predict myocardial viability in patients undergoing revascularization. Am J Cardiol 1999;83:1–5.\nUdelson JE, Coleman PS, Metherall J, Pandian NG, Gomez AR, Griffith JL, et al. Predicting recovery of severe regional ventricular dysfunction. Comparison of resting scintigraphy with 201Tl and 99mTc-sestamibi. Circulation 1994;89:2552–61.\nKerwin WF, Botvinick EH, O’Connell JW, Merrick SH, DeMarco T, Chatterjee K, et al. Ventricular contraction abnormalities in dilated cardiomyopathy: effect of biventricular pacing to correct interventricular dyssynchrony. J Am Coll Cardiol 2000;35:1221–7.\nFauchier L, Marie O, Casset-Senon D, Babuty D, Cosnay P, Fauchier JP. Interventricular and intraventricular dyssynchrony in idiopathic dilated cardiomyopathy: a prognostic study with fourier phase analysis of radionuclide angioscintigraphy. J Am Coll Cardiol 2002;40:2022–30.\nSciagra R, Giaccardi M, Porciani MC, Colella A, Michelucci A, Pieragnoli P, et al. Myocardial perfusion imaging using gated SPECT in heart failure patients undergoing cardiac resynchronization therapy. J Nucl Med 2004;45:164–8.\nYpenburg C, Schalij MJ, Bleeker GB, Steendijk P, Boersma E, Dibbets-Schneider P, et al. Impact of viability and scar tissue on response to cardiac resynchronization therapy in ischaemic heart failure patients. Eur Heart J 2007;28:33–41.\nAdelstein EC, Saba S. Scar burden by myocardial perfusion imaging predicts echocardiographic response to cardiac resynchronization therapy in ischemic cardiomyopathy. 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In this paper we report on the imaging of 5-HT and DA transporters in 28 healthy controls with single-photon emission tomography using iodine-123 labelled 2β-carbomethoxy-3β-(4-iodophenyl)tropane ([123I]β-CIT) as the tracer. The [123I]β-CIT distribution showed the most prominent 5-HT activity in the medial frontal cortex, hypothalamus, midbrain and occipital cortex and the greatest DA activity in the basal ganglia. The specific binding of the 5-HT transporters in the medial frontal cortex was 0.377±0.031 and that of the DA transporters in the basal ganglia, 0.916±0.007. Gjedde-Patlak plots indicated two separate components: the first was assumed to represent 5-HT transporters with a slope of 1.29±0.27 h−1 and the second, DA transporters with a slope of 0.30±0.04 h−1. This distinct kinetic pattern and the fact that 5-HT and DA transporters are situated in different parts of the brain provides an opportunity to study in vivo patients suffering from various neuropsychiatric disorders.",{"EN":1722},"Imaging of serotonin and dopamine transporters in the living human brain",{"VOID":1724},"Kaufman MJ, Madras BK. Severe depletion of cocaine recognition sites associated with the dopamine transporter in Parkinson's diseased striatum.Synapse 1991; 9: 43–49.\nAllard P, Alafuzoff I, Carlsson A, et al. Loss of dopamine uptake sites labelled with [3H]GBR-12935 in Alzheimer's disease.Eur J Neurol 1990; 30: 181–185.\nLinnoila M, Virkkunen M, Scheinin M, et al. Low cerebrospinal fluid 5-hydroxyindoleacetic acid concentration differentiates impulsive from nonimpulsive violent behaviour.Life Sci 1983; 33: 2609–2614.\nVirkkunen M, DeJong J, Bartko J, Goodwin FK, Linnoila M. Relationship of psychobiological variable to recidivism in violent offenders and impulsive fire setters.Arch Gen Psychiatry 1989; 46: 600–603.\nFarde L, Halldin C, Stone-Elander S, Sedvall G. PET analysis of human dopamine subtypes using11C-SCH 23390 and11C-raclopride.Psychopharmacology 1987; 92: 278–284.\nSadzot B, Lemaire C, Cantineuau R, et al. Imaging serotonin-S2 receptors in human with PET and the selective S2 antagonist [18F]altanserine.J Nucl Med 1990; 31: 1584.\nInnis R, Baldwin R, Sybirska E, et al. Single photon emission computed tomography imaging of monoamine reuptake sites in primate brain with [123I]CIT.Eur J Pharmacol 1991; 200: 369–370.\nKuikka JT, Bergström KA, Vanninen E, et al. Initial experience with SPET examinations using [123I]-2β-carbomethoxy-3β-(4-iodophenyl) tropane in human brain.Eur J Nucl Med 1993; 20: 783–786.\nBrücke T, Kornhuber J, Angelberger P, et al. SPECT imaging of dopamine and serotonin transporters with [123I]β-CIT. Binding kinetics in the human brain.J Neural Transm [Gen Sect] 1993; 94:137–146.\nInnis R, Seibyl J, Wallace E, et al. SPECT imaging demonstrates loss of striatal dopamine transporters in Parkinson's disease.Proc Natl Acad Sci USA 1993; 90: 11965–11969.\nBergström KA, Kuikka JT, Ahonen A, Vanninen E. [[123I]-β-CIT, a tracer for dopamine and serotonin reuptake sites, preparation and preliminary SPET studies in humans.J Nucl Biol Med 1994; (in press).\nKuikka JT, Bergström KA, Ahonen A, Länsimies E. The dosimetry of iodine-123 labelled 2β-carbomethoxy-3β-(4-iodo-phenyl) tropane.Eur J Nucl Med 1994; 21: 53–56.\nGjedde A, Christensen O. Estimates of Michaelis-Menten constants for the two membranes of the brain endothelium.J Cereb Blood Flow Metabol 1984; 4: 341–249.\nPatlak CS, Blasberg RG, Fenstermacher JD. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data.J Cereb Blood Flow Metab 1983; 3: 1–7.\nBergström KA, Halldin C, Kuikka JT, et al. Lipophilic metabolite of [123I]β-CIT in human plasma may obstruct quantitation of the dopamine transporter.Synapse 1994, (in press).\nCosta DC, Verhoeff NPLG, Cullum ID, et al. In vivo characterisation of 3-iodo-6-methoxybenzamide123I in humans.Eur J Nucl Med 1990; 16: 813–816.\nBäckström I, Bergström M, Marcusson J. High affinity [3H]paroxetine binding to serotonin uptake sites in human brain.Brain Res 1989; 486: 261–268.\nInnis RB. Single-photon emission tomography imaging of dopamine terminal innervation: a potential clinical tool in Parkinson's disease.Eur J Nucl Med 1994; 21: 1–5.\nBoja JW, Mitchell WM, Patel A, et al. High-affinity binding of [125I]RTI-55 to dopamine and serotonin transporters in rat brain.Synapse 1992; 12: 27–36.",{"VOID":1726},"10.1007\u002FBF00941852","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002FBF00941852",[1729,1744,1759,1772,1787,1802,1817,1830,1843],{"id":1730,"sortIndex":32,"researcher":28,"roles":1731,"affiliations":1732,"properties":1741,"displayName":1743,"givenName":28,"familyName":28},"e9ac35ee-7b65-41c3-9854-7b679d4801c7",[970],[1733],{"id":1734,"sortIndex":32,"affiliation":1735,"properties":28},"9127a0b1-bdca-481e-90e4-7d2886c9e7a7",{"id":1734,"createTime":28,"updateTime":28,"relativeEntities":1736,"slug":28,"properties":1737,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1740,"statistic":28},[],{"title":1738},{"VI":1739},"Department of Clinical Physiology, Kuopio University Hospital, Kuopio, Finland",[],{"title":1742},{"VI":1743},"Jyrki T. 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evaluate the diagnostic potential of PET\u002FMRI with [18F]FDG in comparison to PET\u002FCT in patients with differentiated thyroid cancer suspected or known to have dedifferentiated. The study included 31 thyroidectomized and remnant-ablated patients who underwent a scheduled [18F]FDG PET\u002FCT scan and were then enrolled for a PET\u002FMRI scan of the neck and thorax. The datasets (PET\u002FCT, PET\u002FMRI) were rated regarding lesion count, conspicuity, diameter and characterization. Standardized uptake values were determined for all [18F]FDG-positive lesions. Histology, cytology, and examinations before and after treatment served as the standards of reference. Of 26 patients with a dedifferentiated tumour burden, 25 were correctly identified by both [18F]FDG PET\u002FCT and PET\u002FMRI. Detection rates by PET\u002FCT and PET\u002FMRI were 97 % (113 of 116 lesions) and 85 % (99 of 113 lesions) for malignant lesions, and 100 % (48 of 48 lesions) and 77 % (37 of 48 lesions) for benign lesions, respectively. Lesion conspicuity was higher on PET\u002FCT for both malignant and benign pulmonary lesions and in the overall rating for malignant lesions (p \u003C 0.001). There was a difference between PET\u002FCT and PET\u002FMRI in overall evaluation of malignant lesions (p \u003C 0.01) and detection of pulmonary metastases (p \u003C 0.001). Surgical evaluation revealed three malignant lesions missed by both modalities. PET\u002FMRI additionally failed to detect 14 pulmonary metastases and 11 benign lesions. In patients with thyroid cancer and suspected or known dedifferentiation, [18F]FDG PET\u002FMRI was inferior to low-dose [18F]FDG PET\u002FCT for the assessment of pulmonary status. However, for the assessment of cervical status, [18F]FDG PET\u002FMRI was equal to contrast-enhanced neck [18F]FDG PET\u002FCT. Therefore, [18F]FDG PET\u002FMRI combined with a low-dose CT scan of the thorax may provide an imaging solution when high-quality imaging is needed and high-energy CT is undesirable or the use of a contrast agent is contraindicated.",{"EN":1921},"[18F]FDG PET\u002FCT outperforms [18F]FDG PET\u002FMRI in differentiated thyroid cancer",{"VOID":1923},"Maier TM, Schober O, Gerss J, Görlich D, Wenning C, Schaefers M, et al. Differentiated thyroid cancer patients more than 60 years old paradoxically show an increased life expectancy. J Nucl Med. 2015;56(2):190–5.\nVerburg FA, Mader U, Tanase K, Thies ED, Diessl S, Buck AK, et al. Life expectancy is reduced in differentiated thyroid cancer patients ≥ 45 years old with extensive local tumor invasion, lateral lymph node, or distant metastases at diagnosis and normal in all other DTC patients. J Clin Endocrinol Metab. 2013;98(1):172–80.\nVrachimis A, Riemann B, Gerss J, Maier T, Schober O. Peace of mind for patients with differentiated thyroid cancer? Nuklearmedizin. 2013;52(4):115–20.\nVrachimis A, Wenning C, Gerss J, Dralle H, Vaez Tabassi M, Schober O, et al. Not all DTC patients with N positive disease deserve the attribution \"high risk\". contribution of the MSDS trial. J Surg Oncol. 2015;112(1):9–14.\nSilberstein EB. The problem of the patient with thyroglobulin elevation but negative iodine scintigraphy: the TENIS syndrome. Semin Nucl Med. 2011;41(2):113–20.\nRiemann B, Uhrhan K, Dietlein M, Schmidt D, Kuwert T, Dorn R, et al. Diagnostic value and therapeutic impact of (18)F-FDG-PET\u002FCT in differentiated thyroid cancer. Results of a German multicentre study. Nuklearmedizin. 2013;52(1):1–6.\nKhan N, Oriuchi N, Higuchi T, Zhang H, Endo K. PET in the follow-up of differentiated thyroid cancer. Br J Radiol. 2003;76(910):690–5.\nChandarana H, Heacock L, Rakheja R, DeMello LR, Bonavita J, Block TK, et al. Pulmonary nodules in patients with primary malignancy: comparison of hybrid PET\u002FMR and PET\u002FCT imaging. Radiology. 2013;268(3):874–81.\nBeiderwellen K, Grueneisen J, Ruhlmann V, Buderath P, Aktas B, Heusch P, et al. (18)F]FDG PET\u002FMRI vs. PET\u002FCT for whole-body staging in patients with recurrent malignancies of the female pelvis: Initial results. Eur J Nucl Med Mol Imaging. 2015;42(1):56–65.\nKubiessa K, Purz S, Gawlitza M, Kühn A, Fuchs J, Steinhoff KG, et al. Initial clinical results of simultaneous 18F-FDG PET\u002FMRI in comparison to 18F-FDG PET\u002FCT in patients with head and neck cancer. Eur J Nucl Med Mol Imaging. 2014;41(4):639–48.\nPlatzek I, Beuthien-Baumann B, Schneider M, Gudziol V, Langner J, Schramm G, et al. PET\u002FMRI in head and neck cancer: initial experience. Eur J Nucl Med Mol Imaging. 2013;40(1):6–11.\nQueiroz MA, Hullner M, Kuhn F, Huber G, Meerwein C, Kollias S, et al. PET\u002FMRI and PET\u002FCT in follow-up of head and neck cancer patients. Eur J Nucl Med Mol Imaging. 2014;41(6):1066–75.\nSchwenzer NF, Schraml C, Muller M, Brendle C, Sauter A, Spengler W, et al. Pulmonary lesion assessment: comparison of whole-body hybrid MR\u002FPET and PET\u002FCT imaging – pilot study. Radiology. 2012;264(2):551–8.\nLee KH, Park CM, Lee SM, Lee JM, Cho JY, Paeng JC, et al. Pulmonary nodule detection in patients with a primary malignancy using hybrid PET\u002FMRI: is there value in adding contrast-enhanced MR imaging? PLoS One. 2015;10(6), e0129660.\nAmerican Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer, Cooper DS, Doherty GM, Haugen BR, Kloos RT, Lee SL, et al. Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid. 2009;19(11):1167–214.\nDietlein M, Dressler J, Eschner W, Grünwald F, Lassmann M, Leisner B, et al. Procedure guidelines for radioiodine therapy of differentiated thyroid cancer (version 3). Nuklearmedizin. 2007;46(5):213–9.\nLuster M, Clarke SE, Dietlein M, Lassmann M, Lind P, Oyen WJ, et al. Guidelines for radioiodine therapy of differentiated thyroid cancer. Eur J Nucl Med Mol Imaging. 2008;35(10):1941–59.\nDelso G, Furst S, Jakoby B, Ladebeck R, Ganter C, Nekolla SG, et al. Performance measurements of the Siemens mMR integrated whole-body PET\u002FMR scanner. J Nucl Med. 2011;52(12):1914–22.\nKinahan PE, Townsend DW, Beyer T, Sashin D. Attenuation correction for a combined 3D PET\u002FCT scanner. Med Phys. 1998;25(10):2046–53.\nMartinez-Moller A, Souvatzoglou M, Delso G, Bundschuh RA, Chefd'hotel C, Ziegler SI, et al. Tissue classification as a potential approach for attenuation correction in whole-body PET\u002FMRI: evaluation with PET\u002FCT data. J Nucl Med. 2009;50(4):520–6.\nEisenhauer EA, Therasse P, Bogaerts J, Schwartz LH, Sargent D, Ford R, et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer. 2009;45(2):228–47.\nBland JM, Altman DG. Measuring agreement in method comparison studies. Stat Methods Med Res. 1999;8(2):135–60.\nBrix G, Lechel U, Glatting G, Ziegler SI, Münzing W, Müller SP, et al. Radiation exposure of patients undergoing whole-body dual-modality 18F-FDG PET\u002FCT examinations. J Nucl Med. 2005;46(4):608–13.\nCheng G, Alavi A, Lim E, Werner TJ, Del Bello CV, Akers SR. Dynamic changes of FDG uptake and clearance in normal tissues. Mol Imaging Biol. 2013;15(3):345–52.",{"VOID":1925},"10.1007\u002Fs00259-015-3195-2","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs00259-015-3195-2",[1928,1943,1958,1971,1984,1997,2019],{"id":1929,"sortIndex":32,"researcher":28,"roles":1930,"affiliations":1931,"properties":1940,"displayName":1942,"givenName":28,"familyName":28},"5305953f-8074-4490-b043-8f0472e1a873",[970],[1932],{"id":1933,"sortIndex":32,"affiliation":1934,"properties":28},"b34aba0b-5874-4508-8b12-403cfdf6d278",{"id":1933,"createTime":28,"updateTime":28,"relativeEntities":1935,"slug":28,"properties":1936,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1939,"statistic":28},[],{"title":1937},{"VI":1938},"Department of Nuclear Medicine, University Hospital Münster, Münster, Germany",[],{"title":1941},{"VI":1942},"Alexis 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ductal adenocarcinoma (PDAC) is a molecularly heterogeneous tumor entity with no clinically established imaging biomarkers. We hypothesize that tumor morphology and physiology, including vascularity and perfusion, show variations that can be detected by differences in contrast agent (CA) accumulation measured non-invasively. This work seeks to establish imaging biomarkers for tumor stratification and therapy response monitoring in PDAC, based on this hypothesis. Regional CA accumulation in PDAC was correlated with tumor vascularization, stroma content, and tumor cellularity in murine and human subjects. Changes in CA distribution in response to gemcitabine (GEM) were monitored longitudinally with computed tomography (CT) Hounsfield Units ratio (HUr) of tumor to the aorta or with magnetic resonance imaging (MRI) ΔR1 area under the curve at 60 s tumor-to-muscle ratio (AUC60r). Tissue analyses were performed on co-registered samples, including endothelial cell proliferation and cisplatin tissue deposition as a surrogate of chemotherapy delivery. Tumor cell poor, stroma-rich regions exhibited high CA accumulation both in human (meanHUr 0.64 vs. 0.34, p \u003C 0.001) and mouse PDAC (meanAUC60r 2.0 vs. 1.1, p \u003C 0.001). Compared to the baseline, in vivo CA accumulation decreased specifically in response to GEM treatment in a subset of human (HUr −18%) and mouse (AUC60r −36%) tumors. Ex vivo analyses of mPDAC showed reduced cisplatin delivery (GEM: 0.92 ± 0.5 mg\u002Fg, vs. vehicle: 3.1 ± 1.5 mg\u002Fg, p = 0.004) and diminished endothelial cell proliferation (GEM: 22.3% vs. vehicle: 30.9%, p = 0.002) upon GEM administration. In PDAC, CA accumulation, which is related to tumor vascularization and perfusion, inversely correlates with tumor cellularity. The standard of care GEM treatment results in decreased CA accumulation, which impedes drug delivery. Further investigation is warranted into potentially detrimental effects of GEM in combinatorial therapy regimens.",{"EN":2097},"Functional biomarkers derived from computed tomography and magnetic resonance imaging differentiate PDAC subgroups and reveal gemcitabine-induced 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Perfusion CT to assess response to neoadjuvant chemotherapy and radiation therapy in pancreatic ductal adenocarcinoma: initial experience. Radiology. 2019;292:628–35. https:\u002F\u002Fdoi.org\u002F10.1148\u002Fradiol.2019182561.",{"id":28,"text":2518,"url":28,"identifiers":28},"Kannan P, Kretzschmar WW, Winter H, Warren D, Bates R, Allen PD, et al. Functional parameters derived from magnetic resonance imaging reflect vascular morphology in preclinical tumors and in human liver metastases. Clin Cancer Res. 2018;24:4694–704. https:\u002F\u002Fdoi.org\u002F10.1158\u002F1078-0432.CCR-18-0033.",{"id":28,"text":2520,"url":28,"identifiers":28},"Rajendran R, Huang W, Tang AM, Liang JM, Choo S, Reese T, et al. Early detection of antiangiogenic treatment responses in a mouse xenograft tumor model using quantitative perfusion MRI. Cancer Med. 2014;3:47–60. https:\u002F\u002Fdoi.org\u002F10.1002\u002Fcam4.177.",{"id":28,"text":2522,"url":28,"identifiers":28},"Nebuloni L, Kuhn GA, Vogel J, Muller R. A novel in vivo vascular imaging approach for hierarchical quantification of vasculature using contrast enhanced micro-computed tomography. PLoS One. 2014;9:e86562. https:\u002F\u002Fdoi.org\u002F10.1371\u002Fjournal.pone.0086562.",{"id":28,"text":2524,"url":28,"identifiers":28},"Torphy RJ, Wang Z, True-Yasaki A, Volmar KE, Rashid N, Yeh B, et al. Stromal content is correlated with tissue site, contrast retention, and survival in pancreatic adenocarcinoma. JCO Precis Oncol. 2018;2018 https:\u002F\u002Fdoi.org\u002F10.1200\u002FPO.17.00121.",{"id":28,"text":2526,"url":28,"identifiers":28},"Koay EJ, Lee Y, Cristini V, Lowengrub JS, Kang Y, Lucas FAS, et al. A visually apparent and quantifiable CT imaging feature identifies biophysical subtypes of pancreatic ductal adenocarcinoma. Clin Cancer Res. 2018;24:5883–94. https:\u002F\u002Fdoi.org\u002F10.1158\u002F1078-0432.CCR-17-3668.",{"id":28,"text":2528,"url":28,"identifiers":28},"Jungmann F, Kaissis GA, Ziegelmayer S, Harder F, Schilling C, Yen HY, et al. Prediction of tumor cellularity in resectable PDAC from preoperative computed tomography imaging. Cancers (Basel). 2021;13 https:\u002F\u002Fdoi.org\u002F10.3390\u002Fcancers13092069.",{"id":28,"text":2530,"url":28,"identifiers":28},"Tofts PS, Brix G, Buckley DL, Evelhoch JL, Henderson E, Knopp MV, et al. Estimating kinetic parameters from dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols. J Magn Reson Imaging. 1999;10:223–32. https:\u002F\u002Fdoi.org\u002F10.1002\u002F(SICI)1522-2586(199909)10:33.0.CO;2-S.",{"id":28,"text":2532,"url":28,"identifiers":28},"Tang W, Liu W, Li HM, Wang QF, Fu CX, Wang XH, et al. Quantitative dynamic contrast-enhanced MR imaging for the preliminary prediction of the response to gemcitabine-based chemotherapy in advanced pancreatic ductal carcinoma. Eur J Radiol. 2019;121:108734. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.ejrad.2019.108734.",{"id":28,"text":2534,"url":28,"identifiers":28},"Pijnappel EN, Wassenaar NPM, Gurney-Champion OJ, Klaassen R, van der Lee K, Pleunis-van Empel MCH, et al. Phase I\u002FII study of LDE225 in combination with gemcitabine and nab-paclitaxel in patients with metastatic pancreatic cancer. Cancers (Basel). 2021;13 https:\u002F\u002Fdoi.org\u002F10.3390\u002Fcancers13194869.",{"id":28,"text":2536,"url":28,"identifiers":28},"Kinh Do R, Reyngold M, Paudyal R, Oh JH, Konar AS, LoCastro E, et al. Diffusion-weighted and dynamic contrast-enhanced MRI derived imaging metrics for stereotactic body radiotherapy of pancreatic ductal adenocarcinoma: preliminary findings. Tomography. 2020;6:261–71. https:\u002F\u002Fdoi.org\u002F10.18383\u002Fj.tom.2020.00015.",{"id":28,"text":2538,"url":28,"identifiers":28},"Klaassen R, Steins A, Gurney-Champion OJ, Bijlsma MF, van Tienhoven G, Engelbrecht MRW, et al. Pathological validation and prognostic potential of quantitative MRI in the characterization of pancreas cancer: preliminary experience. Mol Oncol. 2020;14:2176–89. https:\u002F\u002Fdoi.org\u002F10.1002\u002F1878-0261.12688.",{"id":28,"text":2540,"url":28,"identifiers":28},"Khalifa F, Soliman A, El-Baz A, Abou El-Ghar M, El-Diasty T, Gimel'farb G, et al. Models and methods for analyzing DCE-MRI: a review. Med Phys. 2014;41:124301. https:\u002F\u002Fdoi.org\u002F10.1118\u002F1.4898202.",{"id":28,"text":2542,"url":28,"identifiers":28},"Chen CFHL, Lui CC, Lee CC, Weng HH, Tsai YH, Liu HL. In vivo correlation between semi-quantitative hemodynamic parameters and ktrans derived from DCE-MRI of brain tumors. Inc Int J Imaging Syst Technol. 2012;22:132–6. https:\u002F\u002Fdoi.org\u002F10.1002\u002Fima.22013.",{"id":28,"text":2544,"url":28,"identifiers":28},"Steingoetter A, Svensson J, Kosanke Y, Botnar RM, Schwaiger M, Rummeny E, et al. Reference region-based pharmacokinetic modeling in quantitative dynamic contract-enhanced MRI allows robust treatment monitoring in a rat liver tumor model despite cardiovascular changes. Magn Reson Med. 2011;65:229–38. https:\u002F\u002Fdoi.org\u002F10.1002\u002Fmrm.22589.",{"id":28,"text":2546,"url":28,"identifiers":28},"Mendler CT, Feuchtinger A, Heid I, Aichler M, D'Alessandria C, Pirsig S, et al. Tumor uptake of anti-CD20 Fabs depends on tumor perfusion. J Nucl Med. 2016;57:1971–7. https:\u002F\u002Fdoi.org\u002F10.2967\u002Fjnumed.116.176784.",{"id":28,"text":2548,"url":28,"identifiers":28},"Heid I, Steiger K, Trajkovic-Arsic M, Settles M, Esswein MR, Erkan M, et al. Co-clinical assessment of tumor cellularity in pancreatic cancer. Clin Cancer Res. 2017;23:1461–70. https:\u002F\u002Fdoi.org\u002F10.1158\u002F1078-0432.Ccr-15-2432.",{"id":28,"text":2550,"url":28,"identifiers":28},"Trajkovic-Arsic M, Heid I, Steiger K, Gupta A, Fingerle A, Worner C, et al. Apparent Diffusion Coefficient (ADC) predicts therapy response in pancreatic ductal adenocarcinoma. Sci Rep. 2017;7:17038. https:\u002F\u002Fdoi.org\u002F10.1038\u002Fs41598-017-16826-z.",{"id":28,"text":2552,"url":28,"identifiers":28},"Braren R, Curcic J, Remmele S, Altomonte J, Ebert O, Rummeny EJ, et al. Free-breathing quantitative dynamic contrast-enhanced magnetic resonance imaging in a rat liver tumor model using dynamic radial T(1) mapping. Invest Radiol. 2011;46:624–31. https:\u002F\u002Fdoi.org\u002F10.1097\u002FRLI.0b013e31821e30e7.",{"id":28,"text":2554,"url":28,"identifiers":28},"Ballke S, Heid I, Mogler C, Braren R, Schwaiger M, Weichert W, et al. Correlation of in vivo imaging to morphomolecular pathology in translational research: challenge accepted. EJNMMI Res. 2021;11:83. https:\u002F\u002Fdoi.org\u002F10.1186\u002Fs13550-021-00826-2.",{"id":28,"text":2556,"url":28,"identifiers":28},"Winter JM, Ting AH, Vilardell F, Gallmeier E, Baylin SB, Hruban RH, et al. Absence of E-cadherin expression distinguishes noncohesive from cohesive pancreatic cancer. Clin Cancer Res. 2008;14:412–8. https:\u002F\u002Fdoi.org\u002F10.1158\u002F1078-0432.CCR-07-0487.",{"id":28,"text":2558,"url":28,"identifiers":28},"Olive KP, Jacobetz MA, Davidson CJ, Gopinathan A, McIntyre D, Honess D, et al. Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science. 2009;324:1457–61. https:\u002F\u002Fdoi.org\u002F10.1126\u002Fscience.1171362.",{"id":28,"text":2560,"url":28,"identifiers":28},"Matuszewska K, Pereira M, Petrik D, Lawler J, Petrik J. Normalizing tumor vasculature to reduce hypoxia, enhance perfusion, and optimize therapy uptake. Cancers (Basel). 2021;13 https:\u002F\u002Fdoi.org\u002F10.3390\u002Fcancers13174444.",{"id":28,"text":2562,"url":28,"identifiers":28},"Ko AH, LoConte N, Tempero MA, Walker EJ, Kate Kelley R, Lewis S, et al. A phase I study of FOLFIRINOX plus IPI-926, a hedgehog pathway inhibitor, for advanced pancreatic adenocarcinoma. Pancreas. 2016;45:370–5. https:\u002F\u002Fdoi.org\u002F10.1097\u002FMPA.0000000000000458.",{"id":28,"text":2564,"url":28,"identifiers":28},"Mpekris F, Baish JW, Stylianopoulos T, Jain RK. Role of vascular normalization in benefit from metronomic chemotherapy. Proc Natl Acad Sci USA. 2017;114:1994–9. https:\u002F\u002Fdoi.org\u002F10.1073\u002Fpnas.1700340114.",{"id":28,"text":2566,"url":28,"identifiers":28},"Kersemans V, Kannan P, Beech JS, Bates R, Irving B, Gilchrist S, et al. Improving in vivo high-resolution CT imaging of the tumour vasculature in xenograft mouse models through reduction of motion and bone-streak artefacts. PLoS ONE. 2015;10:e0128537. https:\u002F\u002Fdoi.org\u002F10.1371\u002Fjournal.pone.0128537.",{"id":2568,"createTime":2569,"updateTime":2570,"relativeEntities":2571,"slug":2572,"properties":2573,"entityType":964,"verifyStatus":26,"verifyTime":2570,"verifyNote":1120,"languages":28,"translateLanguages":28,"viewCount":32,"primaryUrl":2582,"fullTextUrl":28,"authors":2583,"publicationType":1048,"publisherRelationship":2783,"citationCount":28,"citationInfo":28,"publishDate":2835,"publishYear":2836,"citationAnalyzeStatus":882,"lastCitationAnalyze":28,"indexDatabases":2837,"openAccess":28,"references":28,"isForceReanalyzing":1104},"0074c106-17bb-4b9b-8cd6-6c16fc222994","2024-02-14T18:38:20.771+00:00","2024-12-21T16:19:17.335+00:00",[],"Imaging-cardiac-amyloidosis-a-pilot-study-using-18F-florbetapir-positron-emission-tomography",{"abstract":2574,"title":2576,"references":2578,"doi":2580},{"EN":2575},"Cardiac amyloidosis, a restrictive heart disease with high mortality and morbidity, is underdiagnosed due to limited targeted diagnostic imaging. The primary aim of this study was to evaluate the utility of 18F-florbetapir for imaging cardiac amyloidosis. We performed a pilot study of cardiac 18F-florbetapir PET in 14 subjects: 5 control subjects without amyloidosis and 9 subjects with documented cardiac amyloidosis. Standardized uptake values (SUV) of 18F-florbetapir in the left ventricular (LV) myocardium, blood pool, liver, and vertebral bone were determined. A 18F-florbetapir retention index (RI) was computed. Mean LV myocardial SUVs, target-to-background ratio (TBR, myocardial\u002Fblood pool SUV ratio) and myocardial-to-liver SUV ratio between 0 and 30 min were calculated. Left and right ventricular myocardial uptake of 18F-florbetapir were noted in all the amyloid subjects and in none of the control subjects. The RI, TBR, LV myocardial SUV and LV myocardial to liver SUV ratio were all significantly higher in the amyloidosis subjects than in the control subjects (RI median 0.043 min−1, IQR 0.034 – 0.051 min−1, vs. 0.023 min−1, IQR 0.015 – 0.025 min−1, P = 0.002; TBR 1.84, 1.64 – 2.50, vs. 1.26, IQR 0.91 – 1.36, P = 0.001; LV myocardial SUV 3.84, IQR 1.87 – 5.65, vs. 1.35, IQR 1.17 – 2.28, P = 0.029; ratio of LV myocardial to liver SUV 0.67, IQR 0.44 – 1.64, vs. 0.18, IQR 0.15 – 0.35, P = 0.004). The myocardial RI, TBR and myocardial to liver SUV ratio also distinguished the control subjects from subjects with transthyretin and those with light chain amyloid. \n                           18F-Florbetapir PET may be a promising technique to image light chain and transthyretin cardiac amyloidosis. Its role in diagnosing amyloid in other organ systems and in assessing response to therapy needs to be further studied.",{"EN":2577},"Imaging cardiac amyloidosis: a pilot study using 18F-florbetapir positron emission tomography",{"VOID":2579},"Merlini G, Bellotti V. Molecular mechanisms of amyloidosis. N Engl J Med. 2003;349:583–96.\nFalk RH. Cardiac amyloidosis: a treatable disease, often overlooked. Circulation. 2011;124:1079–85.\nRuberg FL, Berk JL. Transthyretin (TTR) cardiac amyloidosis. Circulation. 2012;126:1286–300.\nSkinner M, Sanchorawala V, Seldin DC, Dember LM, Falk RH, Berk JL, et al. High-dose melphalan and autologous stem-cell transplantation in patients with AL amyloidosis: an 8-year study. Ann Intern Med. 2004;140:85–93.\nKristen AV, Perz JB, Schonland SO, Hegenbart U, Schnabel PA, Kristen JH, et al. Non-invasive predictors of survival in cardiac amyloidosis. Eur J Heart Fail. 2007;9:617–24.\nMiroy GJ, Lai Z, Lashuel HA, Peterson SA, Strang C, Kelly JW. Inhibiting transthyretin amyloid fibril formation via protein stabilization. Proc Natl Acad Sci U S A. 1996;93:15051–6.\nHawkins PN, Lavender JP, Pepys MB. Evaluation of systemic amyloidosis by scintigraphy with 123I-labeled serum amyloid P component. N Engl J Med. 1990;323:508–13.\nYang L, Rieves D, Ganley C. Brain amyloid imaging – FDA approval of florbetapir F18 injection. N Engl J Med. 2012;367:885–7.\nClark CM, Schneider JA, Bedell BJ, Beach TG, Bilker WB, Mintun MA, et al. Use of florbetapir-PET for imaging beta-amyloid pathology. JAMA. 2011;305:275–83.\nLister-James J, Pontecorvo MJ, Clark C, Joshi AD, Mintun MA, Zhang W, et al. Florbetapir F-18: a histopathologically validated beta-amyloid positron emission tomography imaging agent. Semin Nucl Med. 2011;41:300–4.\nChoi SR, Golding G, Zhuang Z, Zhang W, Lim N, Hefti F, et al. Preclinical properties of 18 F-AV-45: a PET agent for Abeta plaques in the brain. J Nucl Med. 2009;50:1887–94.\nAntoni G, Lubberink M, Estrada S, Axelsson J, Carlson K, Lindsjo L, et al. In vivo visualization of amyloid deposits in the heart with 11C-PIB and PET. J Nucl Med. 2013;54:213–20.\nBokhari S, Castano A, Pozniakoff T, Deslisle S, Latif F, Maurer MS. (99m)Tc-pyrophosphate scintigraphy for differentiating light-chain cardiac amyloidosis from the transthyretin-related familial and senile cardiac amyloidoses. Circ Cardiovasc Imaging. 2013;6:195–201.\nPerugini E, Guidalotti PL, Salvi F, Cooke RM, Pettinato C, Riva L, et al. Noninvasive etiologic diagnosis of cardiac amyloidosis using 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid scintigraphy. J Am Coll Cardiol. 2005;46:1076–84.\nSyed IS, Glockner JF, Feng D, Araoz PA, Martinez MW, Edwards WD, et al. Role of cardiac magnetic resonance imaging in the detection of cardiac amyloidosis. JACC Cardiovasc Imaging. 2010;3:155–64.\nBanypersad SM, Sado DM, Flett AS, Gibbs SD, Pinney JH, Maestrini V, et al. Quantification of myocardial extracellular volume fraction in systemic Al amyloidosis: an equilibrium contrast cardiovascular magnetic resonance study. Circ Cardiovasc Imaging. 2013;6:34–9.",{"VOID":2581},"10.1007\u002Fs00259-014-2787-6","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs00259-014-2787-6",[2584,2628,2650,2671,2692,2713,2741,2762],{"id":2585,"sortIndex":32,"researcher":28,"roles":2586,"affiliations":2587,"properties":2625,"displayName":2627,"givenName":28,"familyName":28},"2b038ef5-9884-41a5-9214-304e21a5e630",[970],[2588,2596,2605,2614],{"id":2589,"sortIndex":32,"affiliation":2590,"properties":28},"49941532-31b3-4b9d-83f1-84c3b1954f67",{"id":2589,"createTime":28,"updateTime":28,"relativeEntities":2591,"slug":28,"properties":2592,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2595,"statistic":28},[],{"title":2593},{"VI":2594},"Noninvasive Cardiovascular Imaging Program, Heart and Vascular Center, Departments of Radiology and Medicine (Cardiology), Brigham and Women’s Hospital, Harvard Medical School, Boston, USA",[],{"id":2597,"sortIndex":40,"affiliation":2598,"properties":2604},"4547a31b-61cf-421d-b6ef-54958c1a81a4",{"id":2597,"createTime":28,"updateTime":28,"relativeEntities":2599,"slug":28,"properties":2600,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2603,"statistic":28},[],{"title":2601},{"VI":2602},"Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA",[],{},{"id":2606,"sortIndex":123,"affiliation":2607,"properties":2613},"eb1bf310-73d0-42d7-8a77-1ebf11d14fd3",{"id":2606,"createTime":28,"updateTime":28,"relativeEntities":2608,"slug":28,"properties":2609,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2612,"statistic":28},[],{"title":2610},{"VI":2611},"Cardiovascular Division and the Cardiac Amyloidosis Program, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA",[],{},{"id":2615,"sortIndex":42,"affiliation":2616,"properties":2622},"70c7155a-93a4-48d2-a3ed-d67160aa1ff5",{"id":2615,"createTime":28,"updateTime":28,"relativeEntities":2617,"slug":28,"properties":2618,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2621,"statistic":28},[],{"title":2619},{"VI":2620},"Brigham and Women's Hospital, Boston, United States",[],{"title":2623},{"VI":2624},"Brigham and Women's Hospital, Boston, USA",{"title":2626},{"VI":2627},"Sharmila Dorbala",{"id":2629,"sortIndex":40,"researcher":28,"roles":2630,"affiliations":2631,"properties":2647,"displayName":2649,"givenName":28,"familyName":28},"aa5ae2b4-c9f2-47bf-989e-026eda7af2b4",[970],[2632,2638],{"id":2597,"sortIndex":32,"affiliation":2633,"properties":28},{"id":2597,"createTime":28,"updateTime":28,"relativeEntities":2634,"slug":28,"properties":2635,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2637,"statistic":28},[],{"title":2636},{"VI":2602},[],{"id":2615,"sortIndex":40,"affiliation":2639,"properties":2644},{"id":2615,"createTime":28,"updateTime":28,"relativeEntities":2640,"slug":28,"properties":2641,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2643,"statistic":28},[],{"title":2642},{"VI":2620},[],{"title":2645},{"VI":2646},"Brigham and Women’s Hospital, Boston, USA",{"title":2648},{"VI":2649},"Divya Vangala",{"id":2651,"sortIndex":123,"researcher":28,"roles":2652,"affiliations":2653,"properties":2668,"displayName":2670,"givenName":28,"familyName":28},"7c314a50-14f1-4213-8695-d1e2f52e7d11",[970],[2654,2660],{"id":2597,"sortIndex":32,"affiliation":2655,"properties":28},{"id":2597,"createTime":28,"updateTime":28,"relativeEntities":2656,"slug":28,"properties":2657,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2659,"statistic":28},[],{"title":2658},{"VI":2602},[],{"id":2615,"sortIndex":40,"affiliation":2661,"properties":2666},{"id":2615,"createTime":28,"updateTime":28,"relativeEntities":2662,"slug":28,"properties":2663,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2665,"statistic":28},[],{"title":2664},{"VI":2620},[],{"title":2667},{"VI":2646},{"title":2669},{"VI":2670},"James Semer",{"id":2672,"sortIndex":42,"researcher":28,"roles":2673,"affiliations":2674,"properties":2689,"displayName":2691,"givenName":28,"familyName":28},"b7153e8e-a10b-4533-b2a4-737b010eb647",[970],[2675,2681],{"id":2597,"sortIndex":32,"affiliation":2676,"properties":28},{"id":2597,"createTime":28,"updateTime":28,"relativeEntities":2677,"slug":28,"properties":2678,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2680,"statistic":28},[],{"title":2679},{"VI":2602},[],{"id":2615,"sortIndex":40,"affiliation":2682,"properties":2687},{"id":2615,"createTime":28,"updateTime":28,"relativeEntities":2683,"slug":28,"properties":2684,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2686,"statistic":28},[],{"title":2685},{"VI":2620},[],{"title":2688},{"VI":2624},{"title":2690},{"VI":2691},"Christopher Strader",{"id":2693,"sortIndex":45,"researcher":28,"roles":2694,"affiliations":2695,"properties":2710,"displayName":2712,"givenName":28,"familyName":28},"b1b7e7ea-2b56-472f-9563-75bdf0c719e5",[970],[2696,2702],{"id":2597,"sortIndex":32,"affiliation":2697,"properties":28},{"id":2597,"createTime":28,"updateTime":28,"relativeEntities":2698,"slug":28,"properties":2699,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2701,"statistic":28},[],{"title":2700},{"VI":2602},[],{"id":2615,"sortIndex":40,"affiliation":2703,"properties":2708},{"id":2615,"createTime":28,"updateTime":28,"relativeEntities":2704,"slug":28,"properties":2705,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2707,"statistic":28},[],{"title":2706},{"VI":2620},[],{"title":2709},{"VI":2646},{"title":2711},{"VI":2712},"John R. 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Di Carli",{"id":2742,"sortIndex":48,"researcher":28,"roles":2743,"affiliations":2744,"properties":2759,"displayName":2761,"givenName":28,"familyName":28},"2ddca388-bb10-44ee-a456-f2e63b49ace5",[970],[2745,2751],{"id":2597,"sortIndex":32,"affiliation":2746,"properties":28},{"id":2597,"createTime":28,"updateTime":28,"relativeEntities":2747,"slug":28,"properties":2748,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2750,"statistic":28},[],{"title":2749},{"VI":2602},[],{"id":2615,"sortIndex":40,"affiliation":2752,"properties":2757},{"id":2615,"createTime":28,"updateTime":28,"relativeEntities":2753,"slug":28,"properties":2754,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2756,"statistic":28},[],{"title":2755},{"VI":2620},[],{"title":2758},{"VI":2624},{"title":2760},{"VI":2761},"Stephen C. 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In thalassaemic children the calculated parameters denote that the shortening of the mean cell life is due to early senescence alone, while there is some evidence that in thalassaemic adults additional extracellular destruction mechanisms participate as well. Red cell survival curves from patients with sickle-cell anaemia and s-β-thalassaemia resemble each other, while their parameters indicate an initial rapid loss of radioactivity, early senescence and the presence of extracellular red cell destruction factors.",{"EN":2848},"Mathematical analysis of 51Cr-labelled red cell survival curves in congenital haemolytic anaemias",{"VOID":2850},"Bentley SA (1977) Red cell survival studies reinterpreted. Clin Haematol 6:601–623\nCline MJ, Berlin NI (1963) The red cell chromium elution rate in patients with some gematologic disease. Blood 21:63–69\nEadie GS, Brown IW Jr (1953) Red blood cell survival studies. Blood 8:1110\nEadie GS, Brown IW Jr, Curtis WG (1955) The potential lifespan and ultimate survival of fresh red blood cells in normal healthy recipients as studied by simultaneous Cr-51 tagging and differential hemolysis. J Clin Invest 34:629–636\nEbaugh FG Jr, Emerson CP, Ross JF (1953) The use of radioactive chromium-51 as an erythrocyte tagging agent for the determination of red cell survival in vivo. J Clin Invest 32:1260\nInternational Commitee for Standardization in Hematology, ICSH panel (1972) Recommended methods for radioisotopic erythrocyte survival studies. Am J Clin Pathol 58:71–80\nMalamos B, Belcher EH, Gyftaki, E, Binopoulos D (1961) Radioactive tracer studies of haemoglobin synthesis, erythropoiesis and red cell destruction in congenital haemolytic anaemias. Arbeitsgemeinschaft für Forschung des Landes Nordrhein-Westfalen 18:107–124\nMcCurdy P (1969) 32DFP and 51Cr for measurement of red cell life span in abnormal hemoglobin syndromes. Blood 33:214–224\nMcCurdy PR, Sherman AS (1978) Irreversibly sickled cells and red cell survival in sickle cell anemia. Am J Med 64:253–257\nMollison PL, Veall N (1955) The use of the isotope Cr-51 as a label for red cells. Br J Haematol 1:62\nSinger K, Chernoff AL, Singer L (1951) Studies on abnormal hemoglobins. Blood 6:413\nTyson JW, Dalrymple GV, Meade JH Jr, Marvin HS (1971) Radiochromate RBC survival kinetics in the normal human adult. JNM 12:302–304\nWidman JC, Powsner ER (1974) Red-cell lifetimes calculated from Cr-51 red-cell survival data. Med Phys 1:59–61\nWintrobe M (1974) Clinical hematology. Lea and Febiger, Philadelphia",{"VOID":2852},"10.1007\u002FBF00443928","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002FBF00443928",[2855,2870,2883,2896,2909],{"id":2856,"sortIndex":32,"researcher":28,"roles":2857,"affiliations":2858,"properties":2867,"displayName":2869,"givenName":28,"familyName":28},"82408d49-7fcd-463f-8336-3ab4b273ab3e",[970],[2859],{"id":2860,"sortIndex":32,"affiliation":2861,"properties":28},"4a1217aa-a0d4-4f2d-9222-3d1cd578a4aa",{"id":2860,"createTime":28,"updateTime":28,"relativeEntities":2862,"slug":28,"properties":2863,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2866,"statistic":28},[],{"title":2864},{"VI":2865},"Department of Pathologic Physiology, School of Medicine, University of Athens, Athens, Greece",[],{"title":2868},{"VI":2869},"A. G. 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The investigation was limited to the diagnosis of iliofemoral thrombi. A special injection technique was developed and flow curves, mean transit time and distribution of flow were recorded with a scintillation camera interfaced to a digital computer. Three principally different types of flow curves were observed. Mean transit time was significantly reduced in cases with extensive deep vein thrombosis. Calculation of mean transit time was of value in differentiating particle flow in the superficial veins from passage through the deep veins. Out of 15 legs with thrombi in the iliofemoral region, the distribution of flow was significantly changed in 12. Deep vein thrombosis in the lower leg did not influence mean transit time or distribution of flow in the iliofemoral region. Extensive collateral flow was rare. Ninety per cent of the thrombi were asymptomatic. The method compares favorably with the 125I fibrinogen method and cuff impedance phlebography, in diagnosing iliofemoral thrombi after total hip replacement.",{"EN":2987},"Dynamic radionuclide phlebography",{"VOID":2989},"Barnes, R., Hamilton, G., Mc Donald, G., Rudd, T., Nelp, W., Strandness, D.: Radionuclide venography: Rapid dynamic visualization of the venous system. Surg. Forum. 23, 236 (1972)\nBarnes, R., Hamilton, G., Mc Donald, G., Rudd, T., Nelp, W., Strandness, D.: Radionuclide venography for rapid dynamic evaluation of venous disease. Surgery 73, 706–713 (1973)\nHarris, W., Athanasoulis, C., Waltman, A., Salzman, E.: Cuffimpedance phlebography and 125I fibrinogen scanning versus roentgenographic phlebography for diagnosis of thrombophlebitis following hip surgery. J. Bone Joint Surg. 58-A, 939–944 (1976)\nHayat, D., Reddy, K., Patel, H., Freeman, L.: Radionuclide venography of the lower extremities and inferior vena cava by continous injection and moving bed gamma camera technique. Radiology 121, 748–750 (1976)\nHenkin, R., Yao, J., Quinn, J., Bergan, J.: Radionuclide venography (RNV) in lower extremity venous disease. J. Nucl. Med. 15, 171–175 (1974a)\nHenkin, R., Yao, J., Quinn, J., Bergan, J.: Letter to the Editor. J. Nucl. Med. 15, 915–916 (1974b)\nHighman, J., O'Sullivan, E., Thomas, E.: Isotope venography. Brit. J. Surg. 60, 58–60 (1973)\nHighman, J., O'Sullivan, E.: Isotope venography of pelvic veins. Clin. Radiol. 25, 125–132 (1974)\nJohnson, W., Patten, D., Widrich, W., Nabseth, D.: Technetium 99m venography. Am. J. Surg. 127, 424–428 (1974)\nMc Donald, G., Hamilton, G., Barnes, R., Rudd, T., Strandness, D., Nelp, W.: Radionuclide venography. J. Nucl. Med. 14, 528–530 (1973)\nNylander, G.: Venography of the lower extremities. Abrams: Angiography, Second Edition, pp. 1251–1271. Boston: Little, Brown and Company 1971\nPreston, D., Lee, K., Robinson, R., Martin, N., Rhodes, B.: When radionuclide venography and contrast venography disagree. J. Nucl. Med. 17, 654 (1976)\nRosenthall, L.: Radionuclide venography using 99mTc-pertechnetate and the gammaray scintillation camera. Am. J. Roentgenol. 97, 874–879 (1966)\nRosenthall, L.: Combined inferior cavography, iliac venography and lung imaging with 99mTc-albumin macroaggregates. Radiology 98, 623–626 (1971)\nRyo, U., Colombetti, L., Polin, S., Pinsky, S.: Radionuclide venography: Significance of delayed washout; Visualization of the saphenous system. J. Nucl. Med. 17, 590–595 (1976)\nSevitt, S.: Venous thrombosis and pulmonary embolism. Am. J. Med. 33, 703–716 (1962)\nVan Kirk, O., Burry, M., Jansen, A., Barnett, D., Larson, S.: A simplified approach to radionuclide venography: Concise communication. J. Nucl. Med. 17, 969–971 (1976)\nVlahos, L., Mc Donald, A., Causer, D.: Combination of isotope venography and lung scanning. Brit. J. Radiol. 49, 840–851 (1976)\nWebber, M., Bennet, L., Cragin, M.: Thrombo-phlebitis-demonstration by scintiscanning. Radiology 92, 620–623 (1969)\nWebber, M., Resnick, L., Victery, W., Cragin, M.: Thrombosis scanning: its reliability and usefulness. J. Nucl. Med. 13, 476–477 (1972)\nWebber, M., Pollak, E., Victery, W., Cragin, M., Resnick, L., Grollman, J.: Thrombosis detection by radionuclide particle (MAA) entrapment: Correlation with fibrinogen uptake and venography. 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