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Journal of Medicine and Pharmacy","Tạp chí Y Dược học Cần Thơ",{"EN":487,"VI":488},"\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">04\u002F10\u002F2015 Ministry of Information and Communications allowed Can Tho journal of medicine and pharmacy to operate (102 \u002FGP-BTTTT)\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">07\u002F16\u002F2015 Can Tho journal of medicine and pharmacy is internationally recognized: ISSN 2354-1210\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">In 2016, The journal has been included in the list of medical science journals by The State Council for professorship which is awarded a work score of 0-0.5 points for a published article.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Can Tho Journal of Medicine and Pharmacy welcome original works that haven’t been submitted or published in other medical journals. Posts must contain content related to one of the journal’s categories.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The content published\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The journal is divided into 3 categories:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Scientific research article: are valuable scientific works, which have been researched and accepted.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Overview of medicine, biology and pharmacy: serving the objective of continuing training in the fields of medicine, biology and pharmacy; to systematize classical and modern knowledge.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Update information on new knowledge about medicine, biology, pharmacy in the country and in the world.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Scope\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Publication and introduction of scientific research in the fields:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Medicine (internal medicine, surgery, pediatrics, obstetrics and gynecology, odonto-stomatology, laboratory, oncology, traditional medicine, nursing).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Biology (genetics, biotechnology).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Pharmacology (pharmaceutics, drug quality analysis-control, synthetic pharmaceutical chemistry, biochemistry, pharmacognosy, botany, clinical pharmacy).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- To enhance the quality of undergraduate, postgraduate education, scientifically researching and meet the necessary treatment in hospital.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Introducing the updated domestic and oversea information about science technology to promote scientific research and exchanging technology in local, other universities.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Exchanging pharmaceutical and medical information for social health developing in the Mekong Delta and Vietnam.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The object\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Postgraduate students, student of Can Tho University of Medicine and Pharmacy, scientists from schools, research institutes, hospitals, health centers, pharmaceutical companies of the Mekong Delta; other provinces and regions in Vietnam and other country.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Address\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Headquarters of Can Tho Journal of Medicine and Pharmacy, located Scientific Research and International Cooperation Office: 179 Nguyen Van Cu Street, An Khanh Ward, Ninh Kieu District, Can Tho City, Vietnam.\u003C\u002Fspan>\u003C\u002Fp>","\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Ngày 16\u002F7\u002F2015, Tạp chí Y Dược học Cần Thơ được cấp chỉ số quốc tế: ISSN 2354-1210.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 4\u002F2016, Tạp chí đã được Hội đồng Giáo sư ngành Y đưa vào danh sách các tạp chí khoa học Y học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Năm 2020 Tạp chí Y Dược học Cần Thơ đã được phê duyệt vào danh mục của các Hội đồng Giáo sư ngành Dược học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ ra 12 số\u002Fnăm, 180-200 trang\u002Fsố.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 12\u002F2022 Tạp chí Y Dược học Cần Thơ là thành viên của hệ thống Crossref và từ tháng 01\u002F2023 tạp chí thực hiện bình duyệt online kín 2 chiều nhằm tăng tính minh bạch, tin cậy của các công trình nghiên cứu khoa học và đảm bảo tốt nhất chất lượng khoa học của bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ, mục đích và phạm vi của tạp chí\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ và mục đích hoạt động của tạp chí: xuất bản nhằm mục đích phổ biến kết quả từ các đề tài nghiên cứu khoa học; giao lưu trao đổi khoa học, chia sẻ kinh nghiệm, học tập, đồng thời cập nhật thông tin khoa học mới trong các lĩnh vực y, sinh, dược học trong và ngoài nước.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phạm vi của tạp chí: Tạp chí xuất bản được chia thành 3 chuyên mục: (i) Bài báo nghiên cứu khoa học là kết quả công trình nghiên cứu khoa học có giá trị đã được triển khai nghiên cứu, (ii) Bài tổng quan y, sinh, dược học: phục vụ mục tiêu đào tạo liên tục trong lĩnh vực y, sinh, dược học; nhằm hệ thống hóa những kiến thức kinh điển và hiện đại; (iii) Thông tin cập nhật kiến thức mới về y, sinh, dược học trong nước và trên thế giới.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Chính sách truy cập mở\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ áp dụng chính sách truy cập mở đối với các bài báo đã xuất bản đến với độc giả, nhằm mở rộng cơ hội tiếp cận các kết quả nghiên cứu chất lượng cao và tăng cường trao đổi kiến thức. Tạp chí đăng tải trực tuyến (miễn phí) toàn văn các bài báo được công bố trên website của Tạp chí (https:\u002F\u002Ftapchi.ctump.edu.vn).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đạo đức xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ cam kết tuân thủ đạo đức xuất bản phù hợp với các hướng dẫn và tiêu chuẩn của the Committee on Publication Ethics (COPE), tuân thủ các nguyên tắc của COPE’s Core Practices, Best Practices Guidelines for Journal Editors và Guidelines on Good Publication Practices.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Bản thảo bài báo chỉ được chấp nhận khi được tác giả chịu trách nhiệm chính cam kết các nội dung sau: Các nội dung của bản thảo chưa được đăng tải toàn bộ hoặc một phần ở các tạp chí khác; Tất cả các tác giả đều có đóng góp một cách đáng kể vào quá trình nghiên cứu hoặc chuẩn bị bản thảo và cùng chịu trách nhiệm về các nội dung của bản thảo; Tuân thủ các biện pháp đảm bảo đạo đức nghiên cứu (ví dụ thỏa thuận đồng ý tham gia nghiên cứu).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Cam kết bảo mật\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí cam kết thực hiện và tuân thủ các quy định của luật và các văn bản hướng dẫn liên quan đến bảo mật thông tin cá nhân trên không gian mạng. Các thông tin mà người dùng (tác giả, độc giả, biên tập viên, người phản biện) nhập vào các biểu mẫu trên Hệ thống Quản lý xuất bản trực tuyến của tạp chí chỉ được sử dụng vào các mục đích đã được tuyên bố rõ ràng và sẽ không được cung cấp cho bất kỳ bên thứ ba nào khác, hay dùng vào bất kỳ mục đích nào khác.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phí gửi bài\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng bài: 1.000.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng nhanh: 1.500.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với tác giả là cán bộ viên chức thuộc Trường Đại học Y Dược Cần Thơ thì được hỗ trợ 50% lệ phí gửi đăng bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với sinh viên thực hiện đề tài nghiên cứu khoa học cấp trường được hỗ trợ 100% lệ phí đăng bài ( Tác giả gửi đính kèm “ Quyết định về việc giao tổ chức thực hiện đề tài nghiên cứu khoa học cấp Trường của sinh viên”).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Hình thức nộp lệ phí:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Tiền mặt:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Nộp trực tiếp tại Phòng Tài chính - Kế toán, Trường Đại học Y Dược Cần Thơ, số 179 Nguyễn Văn Cừ, P. An Khánh, Q. Ninh Kiều, thành phố Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Chuyển khoản:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tên Tài khoản: Trường ĐHYD Cần Thơ, Số TK: 0111000115668, tại ngân hàng Vietcombank chi nhánh Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Thời gian: Áp dụng từ ngày 01\u002F02\u002F2023.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">* Phí gửi bài không được hoàn trả khi bài viết bị từ chối hoặc tác giả xin rút bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Quy trình phản biện bài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ thực hiện quy trình phản biện kín hai chiều nghiêm ngặt. Danh tính của những người phản biện không được tiết lộ cho các tác giả và ngược lại. Quy trình thẩm định bài báo đăng gồm các bước sau:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tiếp nhận bản thảo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tác giả liên hệ gửi bản thảo đến Tạp chí qua hệ thống trực tuyến tại website: https:\u002F\u002Ftapchi.ctump.edu.vn. Hướng dẫn về cách đăng ký, gửi bài và chuẩn bị bản thảo được cung cấp trên website của Tạp chí.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sàng lọc sơ bộ\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sau khi Tòa soạn nhận được bài báo của tác giả, Ban Thư ký sẽ tiến hành kiểm tra sơ bộ bài báo (các yêu cầu về nội dung và hình thức). Những bài báo không đúng quy cách hoặc có nội dung không phù hợp hoặc vi phạm bản quyền sẽ bị từ chối (Ban Thư ký thông báo phản hồi đến tác giả trong vòng 1 tuần). Những bài báo đủ điều kiện, được Ban Thư ký tòa soạn chuyển đến Ban Biên tập có cùng chuyên môn với nội dung bài báo để đề xuất người phản biện. Thời gian kể từ khi Ban Biên tập nhận bài báo đến khi đề xuất người phản biện bài báo chậm nhất là 5 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Vòng phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký gửi bài và yêu cầu phản biện đến 02 phản biện độc lập.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Các phản biện gởi nhận xét cho Ban Thư ký. Thời gian từ khi gửi bài cho phản biện đến khi nhận ý kiến của phản biện tối đa là 20 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xử ký kết quả phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Nếu ý kiến đồng ý cho đăng và không cần chỉnh sửa, Ban Thư ký tiếp tục đăng bài theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Nếu ý kiến đồng ý đăng và cần chỉnh sửa, Ban Thư ký sẽ thông tin đến tác giả chỉnh sửa theo yêu cầu của người phản biện. Thời gian chỉnh sửa và gửi lại kéo dài không quá 2 tuần, từ khi tác giả bài báo nhận được thông tin (Quá trình này có thể lặp lại tối đa 2 lần\u002F1 bài báo). Khi có sự thống nhất, đồng ý của người phản biện; bài báo được tiếp tục đăng theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Những bài báo có chất lượng không đạt yêu cầu, cả 2 phản biện không đồng ý cho đăng sẽ bị Tòa soạn từ chối đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký tổng hợp các bản thảo đã được tác giả hoàn thiện sau thẩm định trình Ban Biên tập xem xét, Tổng Biên tập phê duyệt, quyết định bài đăng theo các tiêu chí: sự phù hợp nội dung với tôn chỉ và mục đích, thể loại bài viết (ưu tiên các bài có bài có nghiên cứu chuyên sâu, hàm lượng khoa học cao), đóng góp mới bài báo, bài báo được ưu tiên đăng trong số gần nhất của Tạp chí theo thứ tự: tính thời sự, chất lượng bài báo và thời gian gửi bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Ban Biên tập và Ban Thư ký biên tập bản thảo, chế bản, đọc rà soát lỗi. Thời gian hoàn thành từ 10-15 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Ban Thư ký có trách nhiệm thông báo cho tác giả bài báo (bằng e-mail) về tình hình phê duyệt bài báo, thời gian, số kỳ, tập xuất bản bài báo theo qui định.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">4. Danh sách bài báo theo số Tạp chí được in ấn và phát hành trong năm định kỳ được công bố chính thức trên website: https:\u002F\u002Ftapchi.ctump.edu.vn\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>",{"VOID":490},"wcQ1uqwAAAAJ","2023-05-30T08:17:21.868+00:00",[],[494],{"id":495,"createTime":28,"updateTime":28,"relativeEntities":496,"slug":28,"properties":497,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":507,"parentIds":508,"statistic":28},"6413896b-eca9-442b-a73f-182a58a0ce40",[],{"title":498,"address":501,"country":504,"abbreviation":505},{"EN":499,"VI":500},"Can Tho University of Medicine and Pharmacy","Trường Đại học Y Dược Cần Thơ",{"EN":502,"VI":503},"No 179, Nguyen Van Cu street, An Khanh ward, Ninh Kieu district, Can Tho city, Vietnam","Số 179, đường Nguyễn Văn Cừ, phường An Khánh, quận Ninh Kiều, thành phố Cần Thơ, Việt Nam",{"VOID":15},{"VOID":506},"ctump","http:\u002F\u002Fwww.ctump.edu.vn\u002F",[],[],"https:\u002F\u002Ftapchi.ctump.edu.vn\u002Findex.php\u002Fctump",{"impactFactor":32,"impactFactorByYear":512,"i10Index":32,"i10IndexLast5Year":32,"totalPublication":514,"totalPublicationByYear":515,"totalCitation":520,"totalCitationByYear":521,"totalCitationPerPublication":108,"totalCitationPerPublicationByYear":523,"hindexLast5Year":45,"hindex":45},{"2022":513,"2023":111,"2024":106},0.01,1556,{"2020":47,"2021":516,"2022":517,"2023":518,"2024":519,"2025":122},57,306,801,358,161,{"2021":146,"2022":280,"2023":522},99,{"2021":524,"2022":318,"2023":104},0.23,{"impactFactor":28,"impactFactorByYear":28,"i10Index":123,"i10IndexLast5Year":123,"totalPublication":526,"totalPublicationByYear":527,"totalCitation":526,"totalCitationByYear":528,"totalCitationPerPublication":40,"totalCitationPerPublicationByYear":531,"hindexLast5Year":49,"hindex":49},476,{"0":205,"2019":123,"2021":139,"2022":459,"2023":451,"2024":357,"2025":49,"2026":48},{"2021":42,"2022":123,"2023":161,"2024":529,"2025":360,"2026":530},136,83,{"2021":105,"2022":513,"2023":532,"2024":127,"2025":533,"2026":534},0.62,25.43,13.83,{"id":536,"createTime":537,"updateTime":382,"relativeEntities":538,"slug":539,"properties":540,"entityType":25,"verifyStatus":26,"verifyTime":28,"verifyNote":28,"languages":552,"translateLanguages":28,"viewCount":133,"subjectFields":553,"manageAffiliations":554,"indexDatabases":555,"url":556,"thumbnailPath":557,"statistic":558,"gsStatistic":594,"type":55,"analyzePriority":28},"6984a56a-db70-403b-9cc4-4013e1ceaffa","2023-05-09T06:47:40.346+00:00",[],"T%E1%BA%A1p%20ch%C3%AD%20Nghi%C3%AAn%20c%E1%BB%A9u%20n%C6%B0%E1%BB%9Bc%20ngo%C3%A0i",{"country":541,"issn":542,"title":544,"introduce":547,"gsId":550},{"VOID":15},{"VOID":543},"25252445",{"EN":545,"VI":546},"VNU Journal of Foreign Studies","Tạp chí Nghiên cứu nước ngoài",{"EN":548,"VI":549},"{\"ops\":[{\"insert\":\"\\n\\nThe \\n\"},{\"attributes\":{\"italic\":true},\"insert\":\"VNU Journal of Science\"},{\"insert\":\"\\n was established in 1985 for the publication of national and international research papers in all fields of natural sciences and technology, social sciences and humanities. 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Site-based research or monitoring must have regional or global implications beyond the particular site, such as evaluating processes, mechanisms, or theory under a natural environmental setting.","PENDING",[886,892],{"id":887,"createTime":28,"updateTime":28,"relativeEntities":888,"label":889,"description":891,"parentId":28,"standard":28,"scholarHubFieldId":28},"fd62165d-2af9-4727-927d-7520b8de74ed",[],{"EN":890},"Health, Toxicology and Mutagenesis",{},{"id":893,"createTime":28,"updateTime":28,"relativeEntities":894,"label":895,"description":897,"parentId":28,"standard":28,"scholarHubFieldId":28},"ba398c11-4a62-45f4-af80-7b601f393976",[],{"EN":896},"Environmental Chemistry",{},[899,906],{"id":900,"createTime":28,"updateTime":28,"relativeEntities":901,"slug":28,"properties":902,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":905,"statistic":28},"b89d4fd0-cd7c-45fd-97a1-ec784c5e5841",[],{"title":903},{"EN":904},"Wiley-Blackwell",[],{"id":907,"createTime":28,"updateTime":28,"relativeEntities":908,"slug":28,"properties":909,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":912,"statistic":28},"43d4a537-d044-4372-8544-ca45c3bea38f",[],{"title":910},{"EN":911},"WILEY",[],[914,927],{"id":915,"indexDatabase":916,"url":921,"indexYears":922,"academicFieldIds":923,"indexDatabaseRanking":926},"24a5aa68-334f-4960-8519-07249f2d3a1e",{"id":786,"createTime":28,"updateTime":28,"relativeEntities":917,"label":918,"description":919,"key":792,"publicationTags":920,"standard":28},[],{"EN":789,"VI":789},{"EN":789,"VI":791},[794],"https:\u002F\u002Fwww.scopus.com\u002Fsourceid\u002F25094","1982-2025",[924,925],"95c24511-ec49-4593-81a0-ce6e3c1f9f9e","37f74bc4-acc7-45e0-bf55-b7082b6cfb92","SCOPUS__Q1",{"id":928,"indexDatabase":929,"url":940,"indexYears":28,"academicFieldIds":941,"indexDatabaseRanking":28},"b53c8e87-4ca4-48a1-9b7f-798c404b72d9",{"id":930,"createTime":28,"updateTime":28,"relativeEntities":931,"label":932,"description":934,"key":937,"publicationTags":938,"standard":28},"a4921856-b128-4d9f-8f1f-e80813d3bbd4",[],{"EN":933,"VI":933},"ISI\u002FSCIE - Science Citation Index Expanded",{"EN":935,"VI":936},"SCIE database","Cơ sở dữ liệu SCIE","scie",[939,813],"SCIE","https:\u002F\u002Fmjl.clarivate.com\u002Fsearch-results?issn=0730-7268",[942,943],"1ff2b686-ac7f-4d79-91fb-d25180fb47ca","d35f7cb1-70f1-41cc-b01c-ebcc9f6a923d","https:\u002F\u002Fsetac.onlinelibrary.wiley.com\u002Fjournal\u002F15528618",{"meta":946,"data":948},{"total":947},"362",[949,2125,2637,2994,3464,3650,3948,4561,4756,4935],{"id":950,"createTime":951,"updateTime":951,"relativeEntities":952,"slug":953,"properties":954,"entityType":967,"verifyStatus":26,"verifyTime":951,"verifyNote":968,"languages":969,"translateLanguages":28,"viewCount":32,"primaryUrl":970,"fullTextUrl":28,"authors":971,"publicationType":1135,"publisherRelationship":1136,"citationCount":1186,"citationInfo":1187,"publishDate":1198,"publishYear":1188,"citationAnalyzeStatus":884,"lastCitationAnalyze":28,"indexDatabases":1199,"openAccess":28,"references":1200,"isForceReanalyzing":2124},"cc178cdd-7956-4c08-ba62-98daa704210f","2025-02-07T04:43:58.295+00:00",[],"Nanomaterials-in-the-environment-Behavior-fate-bioavailability-and-effects",{"openalex":955,"mag":957,"abstract":959,"title":961,"pm":963,"doi":965},{"VOID":956},"W2106412044",{"VOID":958},"2106412044",{"EN":960},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\n               \u003Cjats:p>The recent advances in nanotechnology and the corresponding increase in the use of nanomaterials in products in every sector of society have resulted in uncertainties regarding environmental impacts. The objectives of this review are to introduce the key aspects pertaining to nanomaterials in the environment and to discuss what is known concerning their fate, behavior, disposition, and toxicity, with a particular focus on those that make up manufactured nanomaterials. This review critiques existing nanomaterial research in freshwater, marine, and soil environments. It illustrates the paucity of existing research and demonstrates the need for additional research. Environmental scientists are encouraged to base this research on existing studies on colloidal behavior and toxicology. The need for standard reference and testing materials as well as methodology for suspension preparation and testing is also discussed.\u003C\u002Fjats:p>",{"EN":962},"Nanomaterials in the environment: Behavior, fate, bioavailability, and effects",{"VOID":964},"19086204",{"VOID":966},"10.1897\u002F08-090.1","PUBLICATION","Auto Verify",[31],"https:\u002F\u002Facademic.oup.com\u002Fetc\u002Farticle\u002F27\u002F9\u002F1825\u002F7764499",[972,989,1008,1027,1046,1065,1082,1099,1118],{"id":973,"sortIndex":32,"researcher":28,"roles":974,"affiliations":975,"properties":984,"displayName":986,"givenName":28,"familyName":28},"f3b81b54-0f28-4b3f-aa95-f8fb90308691",[],[976],{"id":977,"sortIndex":32,"affiliation":978,"properties":28},"4921d388-e37d-43cc-a86c-8e054469475b",{"id":977,"createTime":28,"updateTime":28,"relativeEntities":979,"slug":28,"properties":980,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":983,"statistic":28},[],{"title":981},{"EN":982},"Institute of Environmental Toxicology, Department of Biology, Clemson University, P.O. 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10.1021\u002Fes001056w",{"doi":1968},"10.1021\u002Fes001056w",{"id":28,"text":1970,"url":28,"identifiers":1971},"Hydutsky, 2007, Optimization of nano- and microiron transport through sand columns using polyelectrolyte mixtures, Environ Sci Technol, 41, 6418, 10.1021\u002Fes0704075",{"doi":1972},"10.1021\u002Fes0704075",{"id":28,"text":1974,"url":28,"identifiers":1975},"Lecoanet, 2004, Laboratory assessment of the mobility of nanomaterials in porous media, Environ Sci Technol, 38, 5164, 10.1021\u002Fes0352303",{"doi":1976},"10.1021\u002Fes0352303",{"id":28,"text":1978,"url":28,"identifiers":1979},"Korcak, 1985, Availability of applied heavy metals as a function of type of soil material and metal source, Soil Sci, 140, 23, 10.1097\u002F00010694-198507000-00004",{"doi":1980},"10.1097\u002F00010694-198507000-00004",{"id":28,"text":1982,"url":28,"identifiers":1983},"Smolders, 2002, Fate and effect of zinc from tire debris in soil, Environ Sci Technol, 36, 3706, 10.1021\u002Fes025567p",{"doi":1984},"10.1021\u002Fes025567p",{"id":28,"text":1986,"url":28,"identifiers":1987},"Voegelin, 2005, Changes in zinc speciation in field soil after contamination with zinc oxide, Environ Sci Technol, 39, 6616, 10.1021\u002Fes047962g",{"doi":1988},"10.1021\u002Fes047962g",{"id":28,"text":1990,"url":28,"identifiers":1991},"Borm, 2006, Research strategies for safety evaluation of nanomaterials. Part V: Role of dissolution in biological fate and effects of nanoscale particles, Toxicol Sci, 90, 23, 10.1093\u002Ftoxsci\u002Fkfj084",{"doi":1992},"10.1093\u002Ftoxsci\u002Fkfj084",{"id":28,"text":1994,"url":28,"identifiers":1995},"Franklin, 2007, Comparative toxicity of nanoparticulate ZnO, bulk ZnO, and ZnCl2 to a freshwater microalga (Pseudokirchneriella subcapitata): The importance of particle solubility, Environ Sci Technol, 41, 8484, 10.1021\u002Fes071445r",{"doi":1828},{"id":28,"text":1997,"url":28,"identifiers":1998},"U.S. Environmental Protection Agency, 2008, Draft nanomaterial research strategy",{},{"id":28,"text":2000,"url":28,"identifiers":2001},"Brayner, 2006, Toxicological impact studies based on Esche-richia coli bacteria in ultrafine ZnO nanoparticles colloidal medium, Nano Letters, 6, 866, 10.1021\u002Fnl052326h",{"doi":2002},"10.1021\u002Fnl052326h",{"id":28,"text":2004,"url":28,"identifiers":2005},"Lin, 2007, Phytotoxicity of nanoparticles: Inhibition of seed germination and root growth, Environ Pollut, 150, 243, 10.1016\u002Fj.envpol.2007.01.016",{"doi":2006},"10.1016\u002Fj.envpol.2007.01.016",{"id":28,"text":2008,"url":28,"identifiers":2009},"Tong, 2007, Impact of fullerene (C-60) on a soil microbial community, Environ Sci Technol, 41, 2985, 10.1021\u002Fes061953l",{"doi":2010},"10.1021\u002Fes061953l",{"id":28,"text":2012,"url":28,"identifiers":2013},"Johansen, 2008, Effects of C60 fullerene nanoparticles on soil bacteria and protozoans, Environ Toxicol Chem, 27, 1895, 10.1897\u002F07-375.1",{"doi":2014},"10.1897\u002F07-375.1",{"id":28,"text":2016,"url":28,"identifiers":2017},"Yang, 2005, Particle surface characteristics may play an important role in phytotoxicity of aluminia nanoparticles, Toxicol Lett, 158, 122, 10.1016\u002Fj.toxlet.2005.03.003",{"doi":1669},{"id":28,"text":2019,"url":28,"identifiers":2020},"Zheng, 2005, Effect of nano-TiO2 on strength of naturally aged seeds and growth of spinach, Biol Trace Elem Res, 104, 83, 10.1385\u002FBTER:104:1:083",{"doi":2021},"10.1385\u002FBTER:104:1:083",{"id":28,"text":2023,"url":28,"identifiers":2024},"Murashov, 2006, Letter to the editor: Comments on ''Particle surface characteristics may play an important role in phytotox-icity of alumina nanoparticles'' by Yang L, Watts, DJ, Toxicol Lett 2005:158, 122–132, Toxicol Lett, 164, 185, 10.1016\u002Fj.toxlet.2006.03.002",{"doi":1673},{"id":28,"text":2026,"url":28,"identifiers":2027},"Magistadm, 1925, The aluminium content of the soil solution and its relation to soil reaction and plant growth, Soil Sci, 20, 181, 10.1097\u002F00010694-192509000-00001",{"doi":2028},"10.1097\u002F00010694-192509000-00001",{"id":28,"text":2030,"url":28,"identifiers":2031},"Lindsay, 1979, Chemical Equilibria in Soils",{},{"id":28,"text":2033,"url":28,"identifiers":2034},"Rozhkov, 2003, Protein interaction with hydrated C(60) fullerene in aqueous solutions, Biochem Biophys Res Commun, 303, 562, 10.1016\u002FS0006-291X(03)00392-9",{"doi":2035},"10.1016\u002FS0006-291X(03)00392-9",{"id":28,"text":1636,"url":28,"identifiers":2037},{"doi":1638},{"id":28,"text":1532,"url":28,"identifiers":2039},{"doi":1534},{"id":28,"text":2041,"url":28,"identifiers":2042},"Tsao, 2001, Inhibition of group A streptococcus infection by carboxyfullerene, Antimicrob Agents Chemother, 45, 1788, 10.1128\u002FAAC.45.6.1788-1793.2001",{"doi":2043},"10.1128\u002FAAC.45.6.1788-1793.2001",{"id":28,"text":2045,"url":28,"identifiers":2046},"Tsao, 2002, In vitro action of carboxyfullerene, J Antimicrob Chemother, 49, 641, 10.1093\u002Fjac\u002F49.4.641",{"doi":2047},"10.1093\u002Fjac\u002F49.4.641",{"id":28,"text":2049,"url":28,"identifiers":2050},"Mashino, 2003, Antibacterial and antiproliferative activity of cationic fullerene derivatives, Bioorg Med Chem Lett, 13, 4395, 10.1016\u002Fj.bmcl.2003.09.040",{"doi":1642},{"id":28,"text":2052,"url":28,"identifiers":2053},"Mashino, 2003, Respiratory chain inhibition by fullerene derivatives: Hydrogen peroxide production caused by fullerene derivatives and a respiratory chain system, Bioorg Med Chem Lett, 11, 1433, 10.1016\u002FS0968-0896(02)00610-7",{"doi":2054},"10.1016\u002FS0968-0896(02)00610-7",{"id":28,"text":2056,"url":28,"identifiers":2057},"Babynin, 2002, Study of mutagenic activity of fullerene and some of its derivatives using His+ reversions of Salmonella typhimurium as an example, Russian Journal of Genetics, 38, 359, 10.1023\u002FA:1015237916596",{"doi":1614},{"id":28,"text":2059,"url":28,"identifiers":2060},"Bagrii, 2001, New in fullerene chemistry (a review), Petroleum Chemistry, 41, 295",{},{"id":28,"text":2062,"url":28,"identifiers":2063},"Bosi, 2000, An-timycobacterial activity of ionic fullerene derivatives, Bioorg Med Chem Lett, 10, 1043, 10.1016\u002FS0960-894X(00)00159-1",{"doi":2064},"10.1016\u002FS0960-894X(00)00159-1",{"id":28,"text":2066,"url":28,"identifiers":2067},"Kang, 2007, Single-walled carbon nanotubes exhibit strong antimicrobial activity, Langmuir, 23, 8670, 10.1021\u002Fla701067r",{"doi":2068},"10.1021\u002Fla701067r",{"id":28,"text":2070,"url":28,"identifiers":2071},"Wei, 2007, Biological properties of carbon nanotubes, Journal of Nanoscience and Nanotechnology, 7, 1284, 10.1166\u002Fjnn.2007.655",{"doi":2072},"10.1166\u002Fjnn.2007.655",{"id":28,"text":2074,"url":28,"identifiers":2075},"Biswas, 2005, Critical review: Nanoparticles and the environment, J Air Waste Manag, 55, 708, 10.1080\u002F10473289.2005.10464656",{"doi":1333},{"id":28,"text":1520,"url":28,"identifiers":2077},{"doi":1522},{"id":28,"text":2079,"url":28,"identifiers":2080},"Kirchner, 2005, Cytotoxicity of colloidal CdSe and CdSe\u002FZnS nanoparticles, Nano Letters, 5, 331, 10.1021\u002Fnl047996m",{"doi":2081},"10.1021\u002Fnl047996m",{"id":28,"text":2083,"url":28,"identifiers":2084},"Hardman, 2006, A toxicologic review of quantum dots: Toxicity depends on physicochemical and environmental factors, Environ Health Perspect, 114, 165, 10.1289\u002Fehp.8284",{"doi":2085},"10.1289\u002Fehp.8284",{"id":28,"text":1778,"url":28,"identifiers":2087},{"doi":1514},{"id":28,"text":2089,"url":28,"identifiers":2090},"Nyberg, 2008, Assessing the impact of nanomaterials on anaerobic microbial communities, Environ Sci Technol, 42, 1938, 10.1021\u002Fes072018g",{"doi":2091},"10.1021\u002Fes072018g",{"id":28,"text":1492,"url":28,"identifiers":2093},{"doi":1494},{"id":28,"text":2095,"url":28,"identifiers":2096},"Goodman, 2004, Toxicity of gold nanoparticles functionalized with cationic and anionic side chains, Bioconjug Chem, 15, 897, 10.1021\u002Fbc049951i",{"doi":2097},"10.1021\u002Fbc049951i",{"id":28,"text":2099,"url":28,"identifiers":2100},"De Windt, 2006, Biological control of the size and reactivity of catalytic Pd(0) produced by She-wanella oneidensis, Antonie van Leeuwenhoek International Journal of General and Molecular Microbiology, 90, 377, 10.1007\u002Fs10482-006-9088-4",{"doi":2101},"10.1007\u002Fs10482-006-9088-4",{"id":28,"text":2103,"url":28,"identifiers":2104},"Rincon, 2004, Effect of pH, inorganic ions, organic matter and H2O2 on E. coli K12 photocatalytic inactivation by TiO2 Implications in solar water disinfection, Appl Catal B: Environ, 51, 283, 10.1016\u002Fj.apcatb.2004.03.007",{"doi":2105},"10.1016\u002Fj.apcatb.2004.03.007",{"id":28,"text":2107,"url":28,"identifiers":2108},"Rincon, 2004, Bactericidal action of illuminated TiO2 on pure Escherichia coli and natural bacterial consortia: Post-irradiation events in the dark and assessment of the effective disinfection time, Appl Catal B: Environ, 49, 99, 10.1016\u002Fj.apcatb.2003.11.013",{"doi":2109},"10.1016\u002Fj.apcatb.2003.11.013",{"id":28,"text":1781,"url":28,"identifiers":2111},{"doi":1783},{"id":28,"text":2113,"url":28,"identifiers":2114},"Huang, 2005, Controllable preparation of Nano-MgO and investigation of its bactericidal properties, J Inorg Biochem, 99, 986, 10.1016\u002Fj.jinorgbio.2004.12.022",{"doi":2115},"10.1016\u002Fj.jinorgbio.2004.12.022",{"id":28,"text":2117,"url":28,"identifiers":2118},"Sawai, 1995, Effect of ceramic powder slurry on spores of Bacillus subtilis, Journal of Chemical Engineering, Japan, 28, 556, 10.1252\u002Fjcej.28.556",{"doi":2119},"10.1252\u002Fjcej.28.556",{"id":28,"text":2121,"url":28,"identifiers":2122},"Sawai, 1996, Effect of particle size and heating temperature of ceramic powders on antibacterial activity of their slurries, Journal of Chemical Engineering, Japan, 29, 251, 10.1252\u002Fjcej.29.251",{"doi":2123},"10.1252\u002Fjcej.29.251",false,{"id":2126,"createTime":2127,"updateTime":2127,"relativeEntities":2128,"slug":2129,"properties":2130,"entityType":967,"verifyStatus":26,"verifyTime":2127,"verifyNote":968,"languages":2143,"translateLanguages":28,"viewCount":32,"primaryUrl":2144,"fullTextUrl":28,"authors":2145,"publicationType":1135,"publisherRelationship":2357,"citationCount":2407,"citationInfo":2408,"publishDate":2417,"publishYear":2409,"citationAnalyzeStatus":884,"lastCitationAnalyze":28,"indexDatabases":2418,"openAccess":28,"references":2419,"isForceReanalyzing":2124},"03f58066-76ae-4121-a235-359172f70472","2024-10-01T08:05:48.054+00:00",[],"Adverse-outcome-pathways-A-conceptual-framework-to-support-ecotoxicology-research-and-risk-assessment",{"openalex":2131,"mag":2133,"abstract":2135,"title":2137,"pm":2139,"doi":2141},{"VOID":2132},"W2000089305",{"VOID":2134},"2000089305",{"EN":2136},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\u003Cjats:p>Ecological risk assessors face increasing demands to assess more chemicals, with greater speed and accuracy, and to do so using fewer resources and experimental animals. New approaches in biological and computational sciences may be able to generate mechanistic information that could help in meeting these challenges. However, to use mechanistic data to support chemical assessments, there is a need for effective translation of this information into endpoints meaningful to ecological risk—effects on survival, development, and reproduction in individual organisms and, by extension, impacts on populations. Here we discuss a framework designed for this purpose, the adverse outcome pathway (AOP). An AOP is a conceptual construct that portrays existing knowledge concerning the linkage between a direct molecular initiating event and an adverse outcome at a biological level of organization relevant to risk assessment. The practical utility of AOPs for ecological risk assessment of chemicals is illustrated using five case examples. The examples demonstrate how the AOP concept can focus toxicity testing in terms of species and endpoint selection, enhance across‐chemical extrapolation, and support prediction of mixture effects. The examples also show how AOPs facilitate use of molecular or biochemical endpoints (sometimes referred to as biomarkers) for forecasting chemical impacts on individuals and populations. In the concluding sections of the paper, we discuss how AOPs can help to guide research that supports chemical risk assessments and advocate for the incorporation of this approach into a broader systems biology framework. Environ. Toxicol. Chem. 2010;29:730–741. © 2009 SETAC\u003C\u002Fjats:p>",{"EN":2138},"Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment",{"VOID":2140},"20821501",{"VOID":2142},"10.1002\u002Fetc.34",[31],"https:\u002F\u002Fsetac.onlinelibrary.wiley.com\u002Fdoi\u002F10.1002\u002Fetc.34",[2146,2165,2182,2199,2214,2231,2246,2263,2280,2295,2310,2325,2340],{"id":2147,"sortIndex":32,"researcher":28,"roles":2148,"affiliations":2149,"properties":2158,"displayName":2162,"givenName":28,"familyName":28},"7d05d1cc-94b0-4ef4-9b17-e2e0dca967ee",[],[2150],{"id":2151,"sortIndex":32,"affiliation":2152,"properties":28},"896259ac-66a1-4489-896d-5267c8018a6f",{"id":2151,"createTime":28,"updateTime":28,"relativeEntities":2153,"slug":28,"properties":2154,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2157,"statistic":28},[],{"title":2155},{"EN":2156},"U.S. Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Mid-Continent Ecology Division, 6201 Condon Boulevard, Duluth, Minnesota 55804",[],{"orcid":2159,"title":2161,"openalex":2163},{"VOID":2160},"https:\u002F\u002Forcid.org\u002F0000-0002-9937-615X",{"EN":2162},"Gerald T. 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The biodegradation products of a major group of nonionic surfactants, the alkylphenol polyethoxylates, are one such group. Some of these chemicals are widespread aquatic pollutants, and bioconcentrate in aquatic biota. Exposure of male rainbow trout \u003Cjats:italic>(Oncorhynchus mykiss)\u003C\u002Fjats:italic> to four different alkylphenolic chemicals caused synthesis of vitellogenin, a process normally dependent on endogenous estrogens, and a concomitant inhibition of testicular growth. The magnitude of these estrogenic effects was dependent on the estrogenic potency of the chemical, the stage of reproductive development of the fish, and the concentration of the chemical in the water. 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G., 1992, Environmental fate of alkylphenol ethoxylates, Soap\u002FCosmetics\u002FChemical Specialities, 72, 27",{},{"id":28,"text":2837,"url":28,"identifiers":2838},"10.1080\u002F03067319208027027",{"doi":2837},{"id":28,"text":2840,"url":28,"identifiers":2841},"10.1002\u002Fetc.5620130507",{"doi":2840},{"id":28,"text":2843,"url":28,"identifiers":2844},"10.1126\u002Fscience.6740328",{"doi":2843},{"id":28,"text":2846,"url":28,"identifiers":2847},"Chemical Manufacturers Association, 1994, Alkylphenol ethoxylates in the environment",{},{"id":28,"text":2849,"url":28,"identifiers":2850},"Giger W., 1987, Behaviour of alkylphenol polyethoxylate surfactants and of nitrilotriacetate in sewage treatment, Water. Sci. 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R., 1985, Estrogens in the Environment, 288",{},{"id":28,"text":2882,"url":28,"identifiers":2883},"10.1126\u002Fscience.7256288",{"doi":2882},{"id":28,"text":2885,"url":28,"identifiers":2886},"10.1289\u002Fehp.94102680",{"doi":2885},{"id":28,"text":2888,"url":28,"identifiers":2889},"10.1016\u002F0044-8486(88)90156-1",{"doi":2888},{"id":28,"text":2891,"url":28,"identifiers":2892},"10.1016\u002F0166-445X(86)90004-4",{"doi":2891},{"id":28,"text":2894,"url":28,"identifiers":2895},"10.1016\u002F0166-445X(85)90024-4",{"doi":2894},{"id":28,"text":2897,"url":28,"identifiers":2898},"Sheahan D. A., 1994, The effects of low levels of 17α‐ethynylestradiol upon plasma vitellogenin levels in male and female rainbow trout, Oncorhynchus mykiss (Walbaum) held at two acclimation temperatures, 99",{},{"id":28,"text":2900,"url":28,"identifiers":2901},"Sumpter J. P., 1985, Trends in Comparative Endocrinology, 355",{},{"id":28,"text":2903,"url":28,"identifiers":2904},"10.1016\u002F0016-6480(89)90054-3",{"doi":2903},{"id":28,"text":2906,"url":28,"identifiers":2907},"Flouriot G., 1993, Monolayer and aggregate cultures of rainbow trout hepatocytes: Long term and stable liver‐specific expression in aggregates, J. Cell Sci., 105, 407, 10.1242\u002Fjcs.105.2.407",{"doi":2908},"10.1242\u002Fjcs.105.2.407",{"id":28,"text":2910,"url":28,"identifiers":2911},"10.1139\u002Fz81-201",{"doi":2910},{"id":28,"text":2913,"url":28,"identifiers":2914},"10.1016\u002F0303-7207(93)90040-Q",{"doi":2913},{"id":28,"text":2916,"url":28,"identifiers":2917},"Xiong F., 1994, The chinook salmon gonadotropin IIb subunit gene contains a strong minimal promoter with a proximal negative element, Mol. Endocrinol., 8, 771",{},{"id":28,"text":2919,"url":28,"identifiers":2920},"10.1210\u002Fme.8.6.782",{"doi":2919},{"id":28,"text":2922,"url":28,"identifiers":2923},"10.1016\u002FS1546-5098(08)60305-2",{"doi":2922},{"id":28,"text":2925,"url":28,"identifiers":2926},"10.1016\u002F0044-8486(89)90207-X",{"doi":2925},{"id":28,"text":2928,"url":28,"identifiers":2929},"10.1016\u002F0044-8486(86)90208-5",{"doi":2928},{"id":28,"text":2931,"url":28,"identifiers":2932},"10.1016\u002F0305-0491(85)90312-8",{"doi":2931},{"id":28,"text":2934,"url":28,"identifiers":2935},"Washburn B. S., 1993, Effects of estrogen on gluconeogenesis and related parameters in male rainbow trout, Am. J. 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L., 1993, Perspectives in Comparative Endocrinology, 304",{},{"id":28,"text":2949,"url":28,"identifiers":2950},"10.1006\u002Fgcen.1994.1089",{"doi":2949},{"id":28,"text":2952,"url":28,"identifiers":2953},"10.1021\u002Fac00285a018",{"doi":2952},{"id":28,"text":2955,"url":28,"identifiers":2956},"10.1007\u002FBF02635812",{"doi":2955},{"id":28,"text":2958,"url":28,"identifiers":2959},"10.1016\u002F0043-1354(94)90200-3",{"doi":2958},{"id":28,"text":2961,"url":28,"identifiers":2962},"10.1021\u002Fes00054a016",{"doi":2961},{"id":28,"text":2964,"url":28,"identifiers":2965},"10.1021\u002Fac00290a035",{"doi":2964},{"id":28,"text":2967,"url":28,"identifiers":2968},"Warhurst A. M., 1995, An environmental assessment of alkylphenol ethoxylates and alkylphenols",{},{"id":28,"text":2970,"url":28,"identifiers":2971},"10.1016\u002F0043-1354(94)90201-1",{"doi":2970},{"id":28,"text":2973,"url":28,"identifiers":2974},"10.1007\u002FBF00214159",{"doi":2973},{"id":28,"text":2976,"url":28,"identifiers":2977},"10.1021\u002Fes00066a004",{"doi":2976},{"id":28,"text":2979,"url":28,"identifiers":2980},"10.1016\u002F0304-4203(90)90020-D",{"doi":2979},{"id":28,"text":2982,"url":28,"identifiers":2983},"10.1016\u002F0045-6535(93)90214-P",{"doi":2982},{"id":28,"text":2985,"url":28,"identifiers":2986},"10.1289\u002Fehp.94102380",{"doi":2985},{"id":28,"text":2988,"url":28,"identifiers":2989},"Sumpter J. P.andS.Jobling.1996.Vitellogenesis as a biomarker for oestrogenic contamination of the aquatic environment.Environ. Health Perspect. (in press).",{"doi":2990},"10.2307\u002F3432529",{"id":28,"text":2992,"url":28,"identifiers":2993},"10.1080\u002F02757549408038554",{"doi":2992},{"id":2995,"createTime":2996,"updateTime":2996,"relativeEntities":2997,"slug":2998,"properties":2999,"entityType":967,"verifyStatus":26,"verifyTime":2996,"verifyNote":968,"languages":3010,"translateLanguages":28,"viewCount":32,"primaryUrl":3011,"fullTextUrl":28,"authors":3012,"publicationType":1135,"publisherRelationship":3030,"citationCount":3080,"citationInfo":3081,"publishDate":3085,"publishYear":3082,"citationAnalyzeStatus":884,"lastCitationAnalyze":28,"indexDatabases":3086,"openAccess":28,"references":3087,"isForceReanalyzing":2124},"f2941445-b274-4084-97be-b708877a7f31","2024-09-22T12:23:11.073+00:00",[],"Bioaccumulation-and-toxicity-of-silver-compounds-A-review",{"openalex":3000,"mag":3002,"abstract":3004,"title":3006,"doi":3008},{"VOID":3001},"W1976504036",{"VOID":3003},"1976504036",{"EN":3005},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\u003Cjats:p>A eview of the literature revealed that bioaccumulation of silver in soil is rather low, even if the soil is amended with silver‐containing sewage sludge. Plants grown on tailings of silver mines were found to have silver primarily in the root systems. In marine and freshwater systems, the highest reported bioconcentration factors (BCFs) were observed in algae (>10\u003Cjats:sup>5\u003C\u002Fjats:sup>), probably because of adsorption of the dissolved silver (<0.45 μm fraction) to the cell surface. In herbivorous organisms (e.g., zooplankton and bivalves), the BCF was lower by about two orders of magnitude. Low amounts of silver were assimilated from food with no substantial biomagnification. In carnivores (e.g., fish), the BCF was also lower by one order of magnitude with no indication of biomagnification. Toxicity of silver occurs mainly in the aqueous phase and depends on the concentration of active, free Ag\u003Cjats:sup>+\u003C\u002Fjats:sup>ions. Accordingly, many processes and water characteristics reduce silver toxicity by stopping the formation of free Ag\u003Cjats:sup>+\u003C\u002Fjats:sup>, binding Ag\u003Cjats:sup>+\u003C\u002Fjats:sup>, or preventing binding of Ag\u003Cjats:sup>+\u003C\u002Fjats:sup>to the reactive surfaces of organisms. The solubility of a silver compound, and the presence of complexing agents (e.g., thiosulfate or chloride), dissolved organic carbon, and competing ions are important. In soil, sewage sludge, and sediments, in which silver sulfide predominates, the toxicity of silver, even at high total concentrations, is very low. The highly soluble silver thiosulfate complex has low toxicity, which can be attributed to the silver complexed by thiosulfate. Silver nitrate is one of the most toxic silver compounds. The toxic potential of silver chloride complexes in seawater is and will be an important issue for investigation. Aquatic chronic tests, long‐term tests, and tests including sensitive life stages show lower toxicity thresholds (˜1 μg Ag\u003Cjats:sup>+\u003C\u002Fjats:sup>\u002FL). The organisms viewed as most sensitive to silver are small aquatic invertebrates, particularly embryonic and larval stages.\u003C\u002Fjats:p>",{"EN":3007},"Bioaccumulation and toxicity of silver compounds: A review",{"VOID":3009},"10.1002\u002Fetc.5620180112",[31],"https:\u002F\u002Fsetac.onlinelibrary.wiley.com\u002Fdoi\u002F10.1002\u002Fetc.5620180112",[3013],{"id":3014,"sortIndex":32,"researcher":28,"roles":3015,"affiliations":3016,"properties":3025,"displayName":3027,"givenName":28,"familyName":28},"101498da-8637-4fc7-9503-5a129f9d29f9",[],[3017],{"id":3018,"sortIndex":32,"affiliation":3019,"properties":28},"4934825a-3851-41a4-bca2-f28775f45fa8",{"id":3018,"createTime":28,"updateTime":28,"relativeEntities":3020,"slug":28,"properties":3021,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":3024,"statistic":28},[],{"title":3022},{"EN":3023},"Aachen University of Technology, Chair of Biology V 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the Transport Fate and Effects of Silver in the Environment Washington DC August 6–9 pp181–184.",{},{"id":28,"text":3397,"url":28,"identifiers":3398},"ShaferMM ArmstrongDE OverdierJT WalkerMT.1994.Partitioning and fate of silver in background streams and effluent‐receiving streams.Proceedings 2nd Argentum International Conference on the Transport Fate and Effects of Silver in the Environment Madison WI USA September 11–14 pp173–178.",{},{"id":28,"text":3400,"url":28,"identifiers":3401},"EricksonRJ AnkleyGT.1996.Sediment quality criteria for metals: Implications for silver regulation.Proceedings 4th Argentum International Conference on the Transport Fate and Effects of Silver in the Environment Madison WI USA August 25–28 pp63–68.",{},{"id":28,"text":3403,"url":28,"identifiers":3404},"Di ToroDM MahonyJD CarbonaroRF LoveJH MorrisseyJC.1996.The bioavalability of silver in sediments.Proceedings 4th Argentum International Conference on the Transport Fate and Effects of Silver in the Environment Madison WI USA August 25–28 pp145–154.",{},{"id":28,"text":3406,"url":28,"identifiers":3407},"10.1016\u002F0048-9697(87)90034-9",{"doi":3406},{"id":28,"text":3409,"url":28,"identifiers":3410},"10.3168\u002Fjds.S0022-0302(68)87038-9",{"doi":3409},{"id":28,"text":3412,"url":28,"identifiers":3413},"U.S. Environmental Protection Agency., 1980, Ambient water quality criteria for silver",{},{"id":28,"text":3415,"url":28,"identifiers":3416},"10.1016\u002F0269-7491(87)90178-3",{"doi":3415},{"id":28,"text":3418,"url":28,"identifiers":3419},"DaskalakisKD.1994.Bioaccumulations of silver in marine bivalve molluscs.Proceedings 2nd Argentum International Conference on the Transport Fate and Effects of Silver in the Environment Madison WI USA September 11–14 pp141–145.",{},{"id":28,"text":3421,"url":28,"identifiers":3422},"10.1016\u002F0043-1354(84)90172-6",{"doi":3421},{"id":28,"text":3424,"url":28,"identifiers":3425},"Wilson WB, 1980, Toxicity of metals to marine phytoplankton cultures",{},{"id":28,"text":3427,"url":28,"identifiers":3428},"10.1080\u002F00039896.1965.10664198",{"doi":3427},{"id":28,"text":3430,"url":28,"identifiers":3431},"10.1016\u002F0147-6513(83)90005-2",{"doi":3430},{"id":28,"text":3433,"url":28,"identifiers":3434},"BirgeWJ ZuiderveenJA.1995.The comparative toxicity of silver to aquatic biota.Proceedings 3rd Argentum International Conference on the Transport Fate and Effects of Silver in the Environment Washington DC August 6–9 pp79–88.",{},{"id":28,"text":3436,"url":28,"identifiers":3437},"CallDJ MarkeeTP BrookeLT PolkinghorneCN GeigerDL.1998.Bioavailability and toxicity of silver toChironomus tentansin water and sediments.Proceedings 5th Argentum International Conference on the Transport Fate and Effects of Silver in the Environment Hamilton ON Canada September 28–October 1 1997.",{},{"id":28,"text":3439,"url":28,"identifiers":3440},"RodgersJHJr DeaverE RogersPL.1994.Evaluations of the bioavalability and toxicity of silver in sediment. Proceedings 2nd Argentum International Conference on the Transport Fate and Effects of Silver in the Environment Madison WI USA September 11–14 pp131–138.",{},{"id":28,"text":3442,"url":28,"identifiers":3443},"GrosellMH HansenHJM.1998.The effects of salinity on110mAg uptake and distribution in European Eel (Anguilla anguilla).Proceedings 5th Argentum International Conference on the Transport Fate and Effects of Silver in the Environment Hamilton ON Canada September 28–October 1 1997.",{},{"id":28,"text":3445,"url":28,"identifiers":3446},"Le Blanc GA, 1984, The influence of speciation on the toxicity of silver to fathead minnow (Pimephales promelas), Environ Toxicol Chem, 3, 37, 10.1002\u002Fetc.5620030106",{"doi":3447},"10.1002\u002Fetc.5620030106",{"id":28,"text":3449,"url":28,"identifiers":3450},"Soyer J, 1963, Contribution to the study of the effects of mercury and silver on marine organisms, Vie Milieu, 24, 1",{},{"id":28,"text":3452,"url":28,"identifiers":3453},"10.1007\u002FBF01689062",{"doi":3452},{"id":28,"text":3455,"url":28,"identifiers":3456},"Zoto GA, 1985, The toxicity of one‐hour silver exposures to early life stages of surf clam, Crassostrea virginica and Mytilus edulis, Mar Ecol Prog Ser, 12, 167",{},{"id":28,"text":3458,"url":28,"identifiers":3459},"Eyster LS, 1984, Development of the surf clam (Spisula solidissima) following exposure of gametes, embryos and larvae to silver, Arch Environ Contam Toxicol, 13, 641, 10.1007\u002FBF01056344",{"doi":3460},"10.1007\u002FBF01056344",{"id":28,"text":3462,"url":28,"identifiers":3463},"DinnelPA StoberQJ LinkJM LetourneauMW RobertsWE FeltonSP NakataniRE.1983.Methodology and validation of a sperm cell toxicity test for testing toxic substances in marine waters. Final Report. University of Washington Seattle WA USA.",{},{"id":3465,"createTime":3466,"updateTime":3466,"relativeEntities":3467,"slug":3468,"properties":3469,"entityType":967,"verifyStatus":26,"verifyTime":3466,"verifyNote":968,"languages":3482,"translateLanguages":28,"viewCount":32,"primaryUrl":3483,"fullTextUrl":28,"authors":3484,"publicationType":1135,"publisherRelationship":3517,"citationCount":3567,"citationInfo":3568,"publishDate":3574,"publishYear":3569,"citationAnalyzeStatus":884,"lastCitationAnalyze":28,"indexDatabases":3575,"openAccess":28,"references":3576,"isForceReanalyzing":2124},"80604d76-8973-434f-8592-f65ed90662ff","2024-10-10T19:02:54.516+00:00",[],"Integrated-biomarker-response-A-useful-tool-for-ecological-risk-assessment",{"openalex":3470,"mag":3472,"abstract":3474,"title":3476,"pm":3478,"doi":3480},{"VOID":3471},"W2040565479",{"VOID":3473},"2040565479",{"EN":3475},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\u003Cjats:p>A battery of biomarkers is often used to evaluate the effects of exposure to chemical contaminants and detect responses to environmental stress. Unfortunately, field application of biomarkers is subject to various constraints (e.g., the availability of living material) that can limit data acquisition and prevent the use of multivariate methods during statistical analysis. In these circumstances, a simple method is needed to summarize biomarker responses and simplify their interpretation in biomonitoring programs. The present study used star plots to display results for the panel of biomarkers used for each station and survey. Integrated biomarker response (IBR) was then computed as the star plot area. Star plots using IBR values instead of biomarker data make it possible to visualize between‐site and\u002For between‐survey differences for comparison with exposure conditions. This approach was applied to sites in the Baltic Sea and the Seine Estuary, English Channel. In both cases, IBR values were visually compared to polycyclic aromatic hydrocarbons (PAH) or polychlorobiphenyls (PCB) levels measured in mussel or fish tissues. The IBR, as an indicator of environmental stress, appears to be a useful tool for scientists and managers in assessing ecological risk.\u003C\u002Fjats:p>",{"EN":3477},"Integrated biomarker response: A useful tool for ecological risk assessment",{"VOID":3479},"12069320",{"VOID":3481},"10.1002\u002Fetc.5620210629",[31],"https:\u002F\u002Fsetac.onlinelibrary.wiley.com\u002Fdoi\u002F10.1002\u002Fetc.5620210629",[3485,3502],{"id":3486,"sortIndex":32,"researcher":28,"roles":3487,"affiliations":3488,"properties":3497,"displayName":3499,"givenName":28,"familyName":28},"77c0e606-db96-4437-aa06-24eeca4f45c3",[],[3489],{"id":3490,"sortIndex":32,"affiliation":3491,"properties":28},"e6977b68-6345-4b81-b93d-47f31cba8a77",{"id":3490,"createTime":28,"updateTime":28,"relativeEntities":3492,"slug":28,"properties":3493,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":3496,"statistic":28},[],{"title":3494},{"EN":3495},"Institut Français de Recherche pour l'Exploitation de la Mer, B.P. 21105, 44311 Nantes Cedex 3, France",[],{"title":3498,"openalex":3500},{"EN":3499},"Benoı̂t 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BL, 1985, The Effects of Stress and Pollution on Marine Animals",{},{"id":28,"text":3581,"url":28,"identifiers":3582},"Huggett JR, 1992, Biomarkers, Biochemical, Physiological, and Histological Markers and Anthropogenic Stress, 347",{},{"id":28,"text":3584,"url":28,"identifiers":3585},"10.1007\u002F978-3-642-84631-1",{"doi":3584},{"id":28,"text":3587,"url":28,"identifiers":3588},"10.1016\u002FS0141-1136(98)00013-0",{"doi":3587},{"id":28,"text":3590,"url":28,"identifiers":3591},"Livingstone DR, 1994, Recent developments in marine invertebrate organic xenobiotic metabolism, Toxicol Ecotoxicol News, 1, 88",{},{"id":28,"text":3593,"url":28,"identifiers":3594},"International Council for the Exploration of the Sea, 2000, Working group on biological effects of contaminants. Marine habitat committee",{},{"id":28,"text":3596,"url":28,"identifiers":3597},"Biological Effects Quality Assurance in Monitoring Programmes, 2000, BEQUALM newsletter",{},{"id":28,"text":3599,"url":28,"identifiers":3600},"Narbonne JF, 1999, Scale of classification based on biochemical markers in mussels: Application to pollution monitoring in European coasts, Biomarkers, 6, 415, 10.1080\u002F135475099230589",{"doi":3601},"10.1080\u002F135475099230589",{"id":28,"text":3603,"url":28,"identifiers":3604},"Marshall Adams S, 1999, Ecological risk assessment in a large river‐reservoir. 6. Bioindicators of fish population health, Environ Toxicol Chem, 18, 628",{},{"id":28,"text":3606,"url":28,"identifiers":3607},"10.1016\u002F0006-2952(61)90145-9",{"doi":3606},{"id":28,"text":3609,"url":28,"identifiers":3610},"10.1016\u002FS0021-9258(19)42083-8",{"doi":3609},{"id":28,"text":3612,"url":28,"identifiers":3613},"10.1016\u002FS0021-9258(19)52451-6",{"doi":3612},{"id":28,"text":3615,"url":28,"identifiers":3616},"10.1016\u002F0025-326X(93)90099-6",{"doi":3615},{"id":28,"text":3618,"url":28,"identifiers":3619},"10.1016\u002F0147-6513(94)90015-9",{"doi":3618},{"id":28,"text":3621,"url":28,"identifiers":3622},"BurgeotT CachotJ VincentF LoizeauV BocquenéG CherelY TronczynskiY Pfhol LeskowiczA GodefroyD BessinettonC AbarnouA.1998.The flounder (Platichthys flesus) a target species used for the evaluation of biological effects of contaminants in the Seine Estuary.Proceedings 8th Annual Meeting of SETAC‐Europe. Bordeaux France April 14–18 p18.",{},{"id":28,"text":3624,"url":28,"identifiers":3625},"10.1016\u002FS0141-1136(98)00128-7",{"doi":3624},{"id":28,"text":3627,"url":28,"identifiers":3628},"Thompson S, 1999, Determination of polychlorinated biphenyls and chlorinated pesticides in environmental biological samples using focused microwave‐assisted extraction, Int J Environ Anal Chem, 75, 1",{},{"id":28,"text":3630,"url":28,"identifiers":3631},"Di Guillio RT, Biomarkers: Research and Application in the Assessment of Environmental Health, 48",{},{"id":28,"text":3633,"url":28,"identifiers":3634},"Salomon JC, 1987, Hydrodynamics of Estuaries, Vol 2—Estuarine Case Studies, 79",{},{"id":28,"text":3636,"url":28,"identifiers":3637},"10.1016\u002FS0025-326X(01)00082-0",{"doi":3636},{"id":28,"text":3639,"url":28,"identifiers":3640},"10.1016\u002FS0141-1136(00)00059-3",{"doi":3639},{"id":28,"text":3642,"url":28,"identifiers":3643},"VonckW.1999.Effects of estuarine conditions on cadmium toxicity and osmoregulatory performance in fish. PhD thesis. Landbouw Wageningen University Wageningen The Netherlands.",{},{"id":28,"text":3645,"url":28,"identifiers":3646},"International Council for the Exploration of the Sea.1999.Report of the working group on statistical aspects of environmental monitoring. ICES‐CM 1999\u002FE:8 Ref. ACME. The Hague The Netherlands.",{},{"id":28,"text":3648,"url":28,"identifiers":3649},"10.1007\u002F978-3-642-84631-1_3",{"doi":3648},{"id":3651,"createTime":3652,"updateTime":3652,"relativeEntities":3653,"slug":3654,"properties":3655,"entityType":967,"verifyStatus":26,"verifyTime":3652,"verifyNote":968,"languages":3668,"translateLanguages":28,"viewCount":32,"primaryUrl":3669,"fullTextUrl":28,"authors":3670,"publicationType":1135,"publisherRelationship":3775,"citationCount":3825,"citationInfo":3826,"publishDate":3831,"publishYear":3827,"citationAnalyzeStatus":884,"lastCitationAnalyze":28,"indexDatabases":3832,"openAccess":28,"references":3833,"isForceReanalyzing":2124},"2b0e67d5-2af1-4a37-b675-e3f12e12892b","2024-09-04T13:07:25.148+00:00",[],"Contamination-of-surface-ground-and-drinking-water-from-pharmaceutical-production",{"openalex":3656,"mag":3658,"abstract":3660,"title":3662,"pm":3664,"doi":3666},{"VOID":3657},"W2149365041",{"VOID":3659},"2149365041",{"EN":3661},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\u003Cjats:p>Low levels of pharmaceuticals are detected in surface, ground, and drinking water worldwide. Usage and incorrect disposal have been considered the major environmental sources of these microcontaminants. Recent publications, however, suggest that wastewater from drug production can potentially be a source of much higher concentrations in certain locations. The present study investigated the environmental fate of active pharmaceutical ingredients in a major production area for the global bulk drug market. Water samples were taken from a common effluent treatment plant near Hyderabad, India, which receives process water from approximately 90 bulk drug manufacturers. Surface water was analyzed from the recipient stream and from two lakes that are not contaminated by the treatment plant. Water samples were also taken from wells in six nearby villages. The samples were analyzed for the presence of 12 pharmaceuticals with liquid chromatography‐mass spectrometry. All wells were determined to be contaminated with drugs. Ciprofloxacin, enoxacin, cetirizine, terbinafine, and citalopram were detected at more than 1 μg\u002FL in several wells. Very high concentrations of ciprofloxacin (14 mg\u002FL) and cetirizine (2.1 mg\u002FL) were found in the effluent of the treatment plant, together with high concentrations of seven additional pharmaceuticals. Very high concentrations of ciprofloxacin (up to 6.5 mg\u002FL), cetirizine (up to 1.2 mg\u002FL), norfloxacin (up to 0.52 mg\u002FL), and enoxacin (up to 0.16 mg\u002FL) were also detected in the two lakes, which clearly shows that the investigated area has additional environmental sources of insufficiently treated industrial waste. Thus, insufficient wastewater management in one of the world's largest centers for bulk drug production leads to unprecedented drug contamination of surface, ground, and drinking water. This raises serious concerns regarding the development of antibiotic resistance, and it creates a major challenge for producers and regulatory agencies to improve the situation.\u003C\u002Fjats:p>",{"EN":3663},"Contamination of surface, ground, and drinking water from pharmaceutical production",{"VOID":3665},"19449981",{"VOID":3667},"10.1897\u002F09-073.1",[31],"https:\u002F\u002Fsetac.onlinelibrary.wiley.com\u002Fdoi\u002F10.1897\u002F09-073.1",[3671,3690,3707,3724,3739,3756],{"id":3672,"sortIndex":32,"researcher":28,"roles":3673,"affiliations":3674,"properties":3683,"displayName":3687,"givenName":28,"familyName":28},"cd5c0821-7499-49f9-9b43-92d2747d86a9",[],[3675],{"id":3676,"sortIndex":32,"affiliation":3677,"properties":28},"c411690d-6b82-4c2c-9232-03118a808f5c",{"id":3676,"createTime":28,"updateTime":28,"relativeEntities":3678,"slug":28,"properties":3679,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":3682,"statistic":28},[],{"title":3680},{"EN":3681},"Department of Chemistry, Umeå University, Linneausväg 6, SE-90187 Umeå, Sweden",[],{"orcid":3684,"title":3686,"openalex":3688},{"VOID":3685},"https:\u002F\u002Forcid.org\u002F0000-0002-3949-7371",{"EN":3687},"Jerker Fick",{"VOID":3689},"A5017224368",{"id":3691,"sortIndex":40,"researcher":28,"roles":3692,"affiliations":3693,"properties":3700,"displayName":3704,"givenName":28,"familyName":28},"b3c65176-b27a-4c10-83ae-0b2c52221def",[],[3694],{"id":3676,"sortIndex":32,"affiliation":3695,"properties":28},{"id":3676,"createTime":28,"updateTime":28,"relativeEntities":3696,"slug":28,"properties":3697,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":3699,"statistic":28},[],{"title":3698},{"EN":3681},[],{"orcid":3701,"title":3703,"openalex":3705},{"VOID":3702},"https:\u002F\u002Forcid.org\u002F0000-0003-1341-7879",{"EN":3704},"Hanna Söderström",{"VOID":3706},"A5040173277",{"id":3708,"sortIndex":123,"researcher":28,"roles":3709,"affiliations":3710,"properties":3717,"displayName":3721,"givenName":28,"familyName":28},"1147f197-941c-428a-b11e-b47031ac359c",[],[3711],{"id":3676,"sortIndex":32,"affiliation":3712,"properties":28},{"id":3676,"createTime":28,"updateTime":28,"relativeEntities":3713,"slug":28,"properties":3714,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":3716,"statistic":28},[],{"title":3715},{"EN":3681},[],{"orcid":3718,"title":3720,"openalex":3722},{"VOID":3719},"https:\u002F\u002Forcid.org\u002F0000-0001-5352-0091",{"EN":3721},"Richard H. 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The long‐term effects of the insecticide chlorpyrifos on the invertebrate community and the dissolved oxygen (DO)–pH–alkalinity–conductivity syndrome, in outdoor experimental ditches, are used as example data. The new method, which we have named the principal response curve method (PRC), is based on redundancy analysis (RDA), adjusted for overall changes in community response over time, as observed in control test systems. This allows the method to focus on the time‐dependent treatment effects. The principal component is plotted against time, yielding a principal response curve of the community for each treatment. The PRC method distills the complexity of time‐dependent, community‐level effects of pollutants into a graphic form that can be appreciated more readily than the results of other currently available multivariate techniques. The PRC method also enables a quantitative interpretation of effects towards the species level.\u003C\u002Fjats:p>",{"EN":4574},"Principal response curves: Analysis of time‐dependent multivariate responses of biological community to stress",{"VOID":4576},"10.1002\u002Fetc.5620180207",[31],"https:\u002F\u002Fsetac.onlinelibrary.wiley.com\u002Fdoi\u002F10.1002\u002Fetc.5620180207",[4580,4599],{"id":4581,"sortIndex":32,"researcher":28,"roles":4582,"affiliations":4583,"properties":4592,"displayName":4596,"givenName":28,"familyName":28},"3fc9d3f9-74d5-4b6b-84c9-5f1e1d453890",[],[4584],{"id":4585,"sortIndex":32,"affiliation":4586,"properties":28},"391b80cc-ad03-4a5e-a34e-faccfbe8b2bf",{"id":4585,"createTime":28,"updateTime":28,"relativeEntities":4587,"slug":28,"properties":4588,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":4591,"statistic":28},[],{"title":4589},{"VI":4590},"DLO Winand Staring Centre for Integrated Land, Soil and Water Research, P.O. Box 125, 6700 AC Wageningen, The Netherlands",[],{"orcid":4593,"title":4595,"openalex":4597},{"VOID":4594},"https:\u002F\u002Forcid.org\u002F0000-0002-7241-4347",{"EN":4596},"van den",{"VOID":4598},"A5017164499",{"id":4600,"sortIndex":40,"researcher":28,"roles":4601,"affiliations":4602,"properties":4611,"displayName":4615,"givenName":28,"familyName":28},"7aa9d7c7-47c3-415d-b783-f6483121b05e",[],[4603],{"id":4604,"sortIndex":32,"affiliation":4605,"properties":28},"47b77db2-72ba-4241-9b1c-f266c0bf3b69",{"id":4604,"createTime":28,"updateTime":28,"relativeEntities":4606,"slug":28,"properties":4607,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":4610,"statistic":28},[],{"title":4608},{"EN":4609},"Centre for Biometry Wageningen, CPRO-DLO P.O. Box 16, 6700 AA Wageningen, The Netherlands",[],{"orcid":4612,"title":4614,"openalex":4616},{"VOID":4613},"https:\u002F\u002Forcid.org\u002F0000-0002-0414-8745",{"EN":4615},"Cajo J. F. ter Braak",{"VOID":4617},"A5015139042",{"url":28,"publisher":4619,"properties":4661},{"id":868,"createTime":869,"updateTime":870,"relativeEntities":4620,"slug":872,"properties":4621,"entityType":25,"verifyStatus":884,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":32,"subjectFields":4626,"manageAffiliations":4635,"indexDatabases":4646,"url":944,"thumbnailPath":28,"statistic":28,"gsStatistic":28,"type":28,"analyzePriority":28},[],{"country":4622,"eissn":4623,"issn":4624,"title":4625},{"VOID":875},{"VOID":877},{"VOID":879},{"EN":881},[4627,4631],{"id":887,"createTime":28,"updateTime":28,"relativeEntities":4628,"label":4629,"description":4630,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":890},{},{"id":893,"createTime":28,"updateTime":28,"relativeEntities":4632,"label":4633,"description":4634,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":896},{},[4636,4641],{"id":900,"createTime":28,"updateTime":28,"relativeEntities":4637,"slug":28,"properties":4638,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":4640,"statistic":28},[],{"title":4639},{"EN":904},[],{"id":907,"createTime":28,"updateTime":28,"relativeEntities":4642,"slug":28,"properties":4643,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":4645,"statistic":28},[],{"title":4644},{"EN":911},[],[4647,4654],{"id":915,"indexDatabase":4648,"url":921,"indexYears":922,"academicFieldIds":4653,"indexDatabaseRanking":926},{"id":786,"createTime":28,"updateTime":28,"relativeEntities":4649,"label":4650,"description":4651,"key":792,"publicationTags":4652,"standard":28},[],{"EN":789,"VI":789},{"EN":789,"VI":791},[794],[924,925],{"id":928,"indexDatabase":4655,"url":940,"indexYears":28,"academicFieldIds":4660,"indexDatabaseRanking":28},{"id":930,"createTime":28,"updateTime":28,"relativeEntities":4656,"label":4657,"description":4658,"key":937,"publicationTags":4659,"standard":28},[],{"EN":933,"VI":933},{"EN":935,"VI":936},[939,813],[942,943],{"issue":4662,"pages":4663,"volume":4665},{"VOID":2786},{"VOID":4664},"138-148",{"VOID":3079},757,{"total":4666,"publishYear":3082,"statisticByYear":4668},{"2012":352,"2013":147,"2014":152,"2015":142,"2016":278,"2017":352,"2018":200,"2019":434,"2020":434,"2021":434,"2022":136,"2023":131,"2024":48},"1999-02-01",[939,926],[4672,4675,4678,4681,4684,4687,4690,4693,4696,4699,4702,4705,4708,4711,4714,4717,4720,4723,4726,4729,4732,4735,4738,4741,4744,4747,4750,4753],{"id":28,"text":4673,"url":28,"identifiers":4674},"10.1002\u002Fetc.5620150718",{"doi":4673},{"id":28,"text":4676,"url":28,"identifiers":4677},"10.1002\u002Fetc.5620150719",{"doi":4676},{"id":28,"text":4679,"url":28,"identifiers":4680},"10.1017\u002FCBO9780511525575.007",{"doi":4679},{"id":28,"text":4682,"url":28,"identifiers":4683},"10.1007\u002F978-1-4757-1904-8",{"doi":4682},{"id":28,"text":4685,"url":28,"identifiers":4686},"10.1007\u002FBF00350650",{"doi":4685},{"id":28,"text":4688,"url":28,"identifiers":4689},"10.1080\u002F11956860.1994.11682237",{"doi":4688},{"id":28,"text":4691,"url":28,"identifiers":4692},"10.2307\u002F2347998",{"doi":4691},{"id":28,"text":4694,"url":28,"identifiers":4695},"10.1002\u002Fbimj.4710360812",{"doi":4694},{"id":28,"text":4697,"url":28,"identifiers":4698},"Ter BraakCJF.1988.CANOCO—A FORRAN Pogram for Canonical Community Ordination by [Partial] [Detrended] [Canonical] Correspondence Analysis Principal Component Analysis and Redundancy Analysis Ver 2.1. LWA‐88‐02. Technical Report. DLO‐Agricultural Mathematics Group Wageningen The Netherlands.",{},{"id":28,"text":4700,"url":28,"identifiers":4701},"10.1007\u002FBF00142333",{"doi":4700},{"id":28,"text":4703,"url":28,"identifiers":4704},"Manly BFJ, 1990, Randomization and Monte Carlo Methods in Biology",{},{"id":28,"text":4706,"url":28,"identifiers":4707},"10.2307\u002F2556164",{"doi":4706},{"id":28,"text":4709,"url":28,"identifiers":4710},"10.1002\u002Fetc.5620160222",{"doi":4709},{"id":28,"text":4712,"url":28,"identifiers":4713},"10.1007\u002FBF00201650",{"doi":4712},{"id":28,"text":4715,"url":28,"identifiers":4716},"10.1111\u002Fj.1442-9993.1993.tb00438.x",{"doi":4715},{"id":28,"text":4718,"url":28,"identifiers":4719},"10.1109\u002F34.67646",{"doi":4718},{"id":28,"text":4721,"url":28,"identifiers":4722},"10.3354\u002Fmeps092205",{"doi":4721},{"id":28,"text":4724,"url":28,"identifiers":4725},"Gower JC, 1996, Biplots",{},{"id":28,"text":4727,"url":28,"identifiers":4728},"10.1002\u002Fetc.5620131207",{"doi":4727},{"id":28,"text":4730,"url":28,"identifiers":4731},"10.1002\u002Fetc.5620150427",{"doi":4730},{"id":28,"text":4733,"url":28,"identifiers":4734},"Shaw JL, 1996, Evaluating macroinvertebrate population and community level effects in outdoor microcosms: Use of in situ bioassays and multivariate analysis, Environ Toxicol Chem, 15, 508",{},{"id":28,"text":4736,"url":28,"identifiers":4737},"Ter Braak CJF, 1992, Multidimensional scaling and regression, Stat Appl, 4, 577",{},{"id":28,"text":4739,"url":28,"identifiers":4740},"10.1214\u002Fss\u002F1038425655",{"doi":4739},{"id":28,"text":4742,"url":28,"identifiers":4743},"10.2307\u002F2533001",{"doi":4742},{"id":28,"text":4745,"url":28,"identifiers":4746},"Johnson ML, 1994, Aquatic Mesocosm Studies in Ecological Risk Assessment, 129",{},{"id":28,"text":4748,"url":28,"identifiers":4749},"Van Buuren S, 1992, Analyzing time‐intensity responses in sensory evaluation, Food Technol, 46, 101",{},{"id":28,"text":4751,"url":28,"identifiers":4752},"10.1080\u002F01621459.1989.10478797",{"doi":4751},{"id":28,"text":4754,"url":28,"identifiers":4755},"Ter BraakCJF.1990.Update notes: CANOCO Ver 3.10. Technical Report. DLO‐Agricultural Mathematics Group Wageningen The Netherlands.",{},{"id":4757,"createTime":4758,"updateTime":4758,"relativeEntities":4759,"slug":4760,"properties":4761,"entityType":967,"verifyStatus":26,"verifyTime":4772,"verifyNote":968,"languages":4773,"translateLanguages":28,"viewCount":32,"primaryUrl":4774,"fullTextUrl":28,"authors":4775,"publicationType":1135,"publisherRelationship":4795,"citationCount":4844,"citationInfo":4845,"publishDate":4848,"publishYear":4846,"citationAnalyzeStatus":884,"lastCitationAnalyze":28,"indexDatabases":4849,"openAccess":28,"references":4850,"isForceReanalyzing":2124},"90d2cbff-e0ed-4918-92e8-80ecfbd8638f","2024-09-22T13:13:35.180+00:00",[],"Groundwater-ubiquity-score-A-simple-method-for-assessing-pesticide-leachability",{"openalex":4762,"mag":4764,"abstract":4766,"title":4768,"doi":4770},{"VOID":4763},"W2160406170",{"VOID":4765},"2160406170",{"EN":4767},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\u003Cjats:p>Government agencies at both the state and federal levels now face increasing pressures to assess the likelihood of pesticide occurrence in well‒water supplies. Screening methodologies are required in order to determine which pesticides now in use should receive the greatest attention with respect to groundwater, and in order to determine whether elaborate and expensive groundwater testing should be required in order to register a new pesticide. Several screening techniques have been proposed recently, some based on threshold values for critical physical properties of the pesticide, and others based on mathematical models of the leaching process. A different approach is taken in this paper, whereby an index is derived based entirely on the physical properties of those pesticides that have been found either leachable or essentially immobile. The index is based on graphical examination of a plot formed by two widely available pesticide properties: half‒life in soil (\u003Cjats:italic>t\u003C\u002Fjats:italic>\u003Cjats:sup>soil\u003C\u002Fjats:sup>\u003Cjats:sub>1\u002F2\u003C\u002Fjats:sub>) and partition coefficient between soil organic carbon and water (\u003Cjats:italic>K\u003C\u002Fjats:italic>\u003Cjats:sub>oc\u003C\u002Fjats:sub>). Other physical properties, such as water solubility, octanol\u002Fwater partition coefficient, and volatility from soil, have often been invoked as indicators of leachability, but they are found in this paper to have no useful power in discriminating between “leachers” and “nonleachers.” Scores assigned with the new screening index agree with the results of several recent well‒water monitoring programs, even though point‒source events are thought to be responsible for some of the observed contamination. A nomogram is given that reduces the task of calculating the index to simply placing a straight edge on a diagram.\u003C\u002Fjats:p>",{"EN":4769},"Groundwater ubiquity score: A simple method for assessing pesticide leachability",{"VOID":4771},"10.1002\u002Fetc.5620080411","2024-09-22T13:13:35.179+00:00",[31],"https:\u002F\u002Fsetac.onlinelibrary.wiley.com\u002Fdoi\u002F10.1002\u002Fetc.5620080411",[4776],{"id":4777,"sortIndex":32,"researcher":28,"roles":4778,"affiliations":4779,"properties":4788,"displayName":4792,"givenName":28,"familyName":28},"70aad36d-91a5-43aa-86d5-466d3a5ddf71",[],[4780],{"id":4781,"sortIndex":32,"affiliation":4782,"properties":28},"36de9d49-0ff8-455e-8a64-f8ba4ddf6dbf",{"id":4781,"createTime":28,"updateTime":28,"relativeEntities":4783,"slug":28,"properties":4784,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":4787,"statistic":28},[],{"title":4785},{"EN":4786},"Monsanto Agricultural Company, 700 Chesterfield Village Parkway, St. Louis, Missouri 63198",[],{"orcid":4789,"title":4791,"openalex":4793},{"VOID":4790},"https:\u002F\u002Forcid.org\u002F0000-0001-6359-7017",{"EN":4792},"David I. Gustafson",{"VOID":4794},"A5026286652",{"url":28,"publisher":4796,"properties":4838},{"id":868,"createTime":869,"updateTime":870,"relativeEntities":4797,"slug":872,"properties":4798,"entityType":25,"verifyStatus":884,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":32,"subjectFields":4803,"manageAffiliations":4812,"indexDatabases":4823,"url":944,"thumbnailPath":28,"statistic":28,"gsStatistic":28,"type":28,"analyzePriority":28},[],{"country":4799,"eissn":4800,"issn":4801,"title":4802},{"VOID":875},{"VOID":877},{"VOID":879},{"EN":881},[4804,4808],{"id":887,"createTime":28,"updateTime":28,"relativeEntities":4805,"label":4806,"description":4807,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":890},{},{"id":893,"createTime":28,"updateTime":28,"relativeEntities":4809,"label":4810,"description":4811,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":896},{},[4813,4818],{"id":900,"createTime":28,"updateTime":28,"relativeEntities":4814,"slug":28,"properties":4815,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":4817,"statistic":28},[],{"title":4816},{"EN":904},[],{"id":907,"createTime":28,"updateTime":28,"relativeEntities":4819,"slug":28,"properties":4820,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":4822,"statistic":28},[],{"title":4821},{"EN":911},[],[4824,4831],{"id":915,"indexDatabase":4825,"url":921,"indexYears":922,"academicFieldIds":4830,"indexDatabaseRanking":926},{"id":786,"createTime":28,"updateTime":28,"relativeEntities":4826,"label":4827,"description":4828,"key":792,"publicationTags":4829,"standard":28},[],{"EN":789,"VI":789},{"EN":789,"VI":791},[794],[924,925],{"id":928,"indexDatabase":4832,"url":940,"indexYears":28,"academicFieldIds":4837,"indexDatabaseRanking":28},{"id":930,"createTime":28,"updateTime":28,"relativeEntities":4833,"label":4834,"description":4835,"key":937,"publicationTags":4836,"standard":28},[],{"EN":933,"VI":933},{"EN":935,"VI":936},[939,813],[942,943],{"issue":4839,"pages":4840,"volume":4842},{"VOID":4508},{"VOID":4841},"339-357",{"VOID":4843},"8",739,{"total":4844,"publishYear":4846,"statisticByYear":4847},1989,{"2012":148,"2013":135,"2014":148,"2015":142,"2016":128,"2017":128,"2018":136,"2019":137,"2020":122,"2021":141,"2022":137,"2023":138,"2024":148},"1989-04-01",[939,926],[4851,4854,4857,4860,4863,4866,4869,4872,4875,4878,4881,4884,4887,4890,4893,4896,4899,4902,4905,4908,4911,4914,4917,4920,4923,4926,4929,4932],{"id":28,"text":4852,"url":28,"identifiers":4853},"Lyman W. J., 1982, Handbook of Chemical Property Estimation Methods: Environmental Behavior of Organic Compounds",{},{"id":28,"text":4855,"url":28,"identifiers":4856},"Rao P. S. C., 1985, Indices for ranking the potential for pesticide contamination of groundwater, Proc. Soil Crop Sci. Soc. Fla., 44, 1",{},{"id":28,"text":4858,"url":28,"identifiers":4859},"Wilkerson M. R., 1986, The Pesticide Contamination Prevention Act: Setting Specific Numerical Values",{},{"id":28,"text":4861,"url":28,"identifiers":4862},"10.2134\u002Fjeq1987.00472425001600040022x",{"doi":4861},{"id":28,"text":4864,"url":28,"identifiers":4865},"10.1111\u002Fj.1745-6584.1982.tb01391.x",{"doi":4864},{"id":28,"text":4867,"url":28,"identifiers":4868},"Carsel R. F., 1984, Users Manual for the Pesticide Root Zone Model (PRZM): Release I",{},{"id":28,"text":4870,"url":28,"identifiers":4871},"Dean J. D., 1984, Leaching Evaluation of Agricultural Chemicals (LEACH) Handbook",{},{"id":28,"text":4873,"url":28,"identifiers":4874},"10.1021\u002Fbk-1984-0259.ch018",{"doi":4873},{"id":28,"text":4876,"url":28,"identifiers":4877},"U.S. Environmental Protection Agency., 1987, Small Scale Prospective Study Design",{},{"id":28,"text":4879,"url":28,"identifiers":4880},"10.1061\u002F(ASCE)0733-9429(1984)110:6(707)",{"doi":4879},{"id":28,"text":4882,"url":28,"identifiers":4883},"10.1002\u002Fps.2780220204",{"doi":4882},{"id":28,"text":4885,"url":28,"identifiers":4886},"Soils 5 Database.1988. University of Illinois and U.S. Army Corps of Engineers Champaign IL.",{},{"id":28,"text":4888,"url":28,"identifiers":4889},"Nash R. G., 1988, Environmental Chemistry of Herbicides: Volume I, 131",{},{"id":28,"text":4891,"url":28,"identifiers":4892},"Voss C. I.1984.A Finite–Element Simulation Model for Saturated–Unsaturated Fluid–Density–Dependent Groundwater Flow with Energy Transport or Chemically Reactive Single–Species Solute Transport (SUTRA). USGS Water–Resources Investigations Report 84–4369. United States Geological Survey U.S. Government Printing Office Washington DC.",{},{"id":28,"text":4894,"url":28,"identifiers":4895},"10.2136\u002Fsssaj1985.03615995004900060002x",{"doi":4894},{"id":28,"text":4897,"url":28,"identifiers":4898},"10.1080\u002F00986448808940435",{"doi":4897},{"id":28,"text":4900,"url":28,"identifiers":4901},"PHYS: Physical Property Database.1988. Monsanto Agricultural Company St. Louis MO.",{},{"id":28,"text":4903,"url":28,"identifiers":4904},"Klaseus T. G. G. C.BuzickyandE. C.Schneider1988.Pesticides and Groundwater: Surveys of Selected Minnesota Wells. Minnesota Departments of Health and Agriculture. Minneapolis (Department of Health) and St. Paul (Department of Agriculture) MN.",{},{"id":28,"text":4906,"url":28,"identifiers":4907},"Wisconsin Department of Natural Resources.1987.Summary of the Problem Assessment Monitoring Program. Madison WI.",{},{"id":28,"text":4909,"url":28,"identifiers":4910},"Industrieverband Pflanzenschutz Federal Republic of Germany.1988.IPS raw water monitoring: An in–depth analysis of the occurrence of the active ingredients of pesticides in drinking water resources. Bonn West Germany.",{},{"id":28,"text":4912,"url":28,"identifiers":4913},"Iowa Department of Natural Resources.1988.Pesticide and Synthetic Organic Compound Survey: Report to the Iowa General Assembly on the Results of the Water Systems Monitoring Required by House Bill 2303. Des Moines IA.",{},{"id":28,"text":4915,"url":28,"identifiers":4916},"Bear J, 1972, Dynamics of Fluids in Porous Media",{},{"id":28,"text":4918,"url":28,"identifiers":4919},"Dullien F. A. L., 1979, Porous Media: Fluid Transport and Pore Structure",{},{"id":28,"text":4921,"url":28,"identifiers":4922},"Wang H. F., 1982, Introduction to Groundwater Modeling: Finite Difference and Finite Element Techniques",{},{"id":28,"text":4924,"url":28,"identifiers":4925},"10.1139\u002Fl78-062",{"doi":4924},{"id":28,"text":4927,"url":28,"identifiers":4928},"10.1016\u002F0048-9697(81)90165-0",{"doi":4927},{"id":28,"text":4930,"url":28,"identifiers":4931},"10.1017\u002FS0022112083002116",{"doi":4930},{"id":28,"text":4933,"url":28,"identifiers":4934},"Anderson M. P., 1984, Groundwater Contamination: Studies in Geophysics, 37",{},{"id":4936,"createTime":4937,"updateTime":4938,"relativeEntities":4939,"slug":4940,"properties":4941,"entityType":967,"verifyStatus":26,"verifyTime":4960,"verifyNote":968,"languages":4961,"translateLanguages":4962,"viewCount":32,"primaryUrl":4963,"fullTextUrl":28,"authors":4964,"publicationType":1135,"publisherRelationship":5067,"citationCount":5116,"citationInfo":5117,"publishDate":5120,"publishYear":5118,"citationAnalyzeStatus":5121,"lastCitationAnalyze":5122,"indexDatabases":5123,"openAccess":28,"references":5124,"isForceReanalyzing":2124},"7cc8d1f7-2958-4d1c-808e-91f1341a19b2","2025-01-02T12:36:54.962+00:00","2026-07-18T16:48:28.108+00:00",[],"Occurrence-of-neutral-and-acidic-drugs-in-the-effluents-of-Canadian-sewage-treatment-plants",{"mag":4942,"gsPaper":4944,"keywords":4946,"openalex":4948,"abstract":4950,"title":4953,"pm":4956,"doi":4958},{"VOID":4943},"1973814811",{"VOID":4945},"[\"10164066967774211388\"]",{"VI":4947},"",{"VOID":4949},"W1973814811",{"VI":4951,"EN":4952},"\u003Cjats:title>Tóm tắt\u003C\u002Fjats:title>\u003Cjats:p>Các mẫu nước đầu vào (chưa qua xử lý) và nước thải (đã qua xử lý) từ 18 nhà máy xử lý nước thải (WWTP) tại 14 đô thị ở Canada đã được phân tích để kiểm tra dư lượng của một số loại thuốc kê đơn và không kê đơn. Nhiều loại thuốc trung tính và axit đã được phát hiện trong nước thải, bao gồm các chất giảm đau\u002Fkháng viêm, chất điều hòa lipid và thuốc chống động kinh, carbamazepine. Dư lượng đã được chiết xuất từ nước thải bằng phương pháp chiết xuất pha rắn, sau đó hoặc là methyl hóa và phân tích các thuốc axit bằng sắc ký khí\u002Fkỹ thuật khối phổ, hoặc phân tích trực tiếp các thuốc trung tính bằng sắc ký lỏng\u002Fkỹ thuật khối phổ nối tiếp. Các thuốc giảm đau\u002Fkháng viêm như ibuprofen và naproxen, cũng như chất chuyển hóa của axit acetylsalicylic, axit salicylic, thường được phát hiện trong nước thải cuối với nồng độ μg\u002FL. Chất điều hòa lipid axit clofibric và thuốc giảm đau\u002Fkháng viêm diclofenac không được phát hiện trong bất kỳ mẫu nước thải cuối nào, điều này không nhất quán với dữ liệu từ châu Âu. Tiền chất của axit clofibric, clofibrate, không được kê đơn rộng rãi như một chất điều hòa lipid ở Canada. Tuy nhiên, các chất điều hòa lipid bezafibrate và gemfibrozil đã được phát hiện trong một số mẫu nước đầu vào và nước thải. Các thuốc hóa trị liệu ifosfamide và cyclophosphamide cùng với thuốc chống viêm phenazone không được phát hiện trong mẫu nước đầu vào hoặc nước thải, nhưng thuốc giãn mạch pentoxyfylline đã được phát hiện với nồng độ ng\u002FL trong một số nước thải cuối. Sự phổ biến của carbamazepine với nồng độ cao tới 2.3 μg\u002FL có thể được giải thích bởi việc sử dụng loại thuốc này cho các mục đích điều trị khác ngoài điều trị động kinh và khả năng chống lại việc loại bỏ trong các nhà máy xử lý nước thải. Tỷ lệ loại bỏ ibuprofen và naproxen dường như tăng cao ở các nhà máy xử lý nước thải có thời gian lưu giữ thủy lực cho nước thải lớn hơn 12 giờ.\u003C\u002Fjats:p>","\u003Cjats:title>Abstract\u003C\u002Fjats:title>\u003Cjats:p>Samples of influent (untreated) and effluent (treated) from 18 sewage treatment plants (STPs) in 14 municipalities in Canada were analyzed for residues of selected prescription and nonprescription drugs. Several neutral and acidic drugs were detected in effluents, including analgesic\u002Fanti‐inflammatory agents, lipid regulators, and an antiepileptic drug, carbamazepine. Residues were extracted from effluents by solid‐phase extraction, followed by either methylation and analysis of acidic drugs by gas chromatography\u002Fmass spectrometry or direct analysis of neutral drugs by liquid chromatography\u002Ftandem mass spectrometry. Analgesic\u002Fanti‐inflammatory drugs such as ibuprofen and naproxen, as well as the metabolite of acetylsalicyclic acid, salicylic acid, were often detected in final effluents at μg\u002FL concentrations. The acidic lipid regulator, clofibric acid, and the analgesic\u002Fanti‐inflammatory drug diclofenac were not detected in any final effluent samples, which is not consistent with data from Europe. The precursor to clofibric acid, clofibrate, is not widely prescribed as a lipid regulator in Canada. However, the lipid regulators bezafibrate and gemfibrozil were detected in some samples of influent and effluent. The chemotherapy drugs ifosfamide and cyclophosphamide and the anti‐inflammatory phenazone were not detected in influent or effluent samples, but the vasodilator drug pentoxyfylline was detected at ng\u002FL concentrations in some final effluents. The widespread occurrence of carbamazepine at concentrations as high as 2.3 μg\u002FL may be explained by use of this drug for other therapeutic purposes besides treatment of epilepsy and its resistance to elimination in STPs. The rates of elimination of ibuprofen and naproxen appeared to be elevated in STPs with hydraulic retention times for sewage greater than 12 h.\u003C\u002Fjats:p>",{"EN":4954,"VI":4955},"Occurrence of neutral and acidic drugs in the effluents of Canadian sewage treatment plants","Sự xuất hiện của thuốc trung tính và axit trong nước thải của các nhà máy xử lý nước thải ở Canada",{"VOID":4957},"14713026",{"VOID":4959},"10.1897\u002F02-469","2025-01-02T12:36:54.961+00:00",[31],[30],"https:\u002F\u002Fsetac.onlinelibrary.wiley.com\u002Fdoi\u002F10.1897\u002F02-469",[4965,4984,4999,5016,5033,5052],{"id":4966,"sortIndex":32,"researcher":28,"roles":4967,"affiliations":4968,"properties":4977,"displayName":4981,"givenName":28,"familyName":28},"db940361-c79e-4ac8-a1ea-361e62dac39e",[],[4969],{"id":4970,"sortIndex":32,"affiliation":4971,"properties":28},"2d922445-369a-49e6-ba2a-9da3ec4bd546",{"id":4970,"createTime":28,"updateTime":28,"relativeEntities":4972,"slug":28,"properties":4973,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":4976,"statistic":28},[],{"title":4974},{"EN":4975},"Water Quality Centre, Trent University, Peterborough, Ontario, Canada K9J 7B8",[],{"orcid":4978,"title":4980,"openalex":4982},{"VOID":4979},"https:\u002F\u002Forcid.org\u002F0000-0002-6807-9048",{"EN":4981},"Chris D. 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