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Journal of Medicine and Pharmacy","Tạp chí Y Dược học Cần Thơ",{"EN":487,"VI":488},"\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">04\u002F10\u002F2015 Ministry of Information and Communications allowed Can Tho journal of medicine and pharmacy to operate (102 \u002FGP-BTTTT)\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">07\u002F16\u002F2015 Can Tho journal of medicine and pharmacy is internationally recognized: ISSN 2354-1210\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">In 2016, The journal has been included in the list of medical science journals by The State Council for professorship which is awarded a work score of 0-0.5 points for a published article.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Can Tho Journal of Medicine and Pharmacy welcome original works that haven’t been submitted or published in other medical journals. Posts must contain content related to one of the journal’s categories.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The content published\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The journal is divided into 3 categories:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Scientific research article: are valuable scientific works, which have been researched and accepted.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Overview of medicine, biology and pharmacy: serving the objective of continuing training in the fields of medicine, biology and pharmacy; to systematize classical and modern knowledge.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Update information on new knowledge about medicine, biology, pharmacy in the country and in the world.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Scope\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Publication and introduction of scientific research in the fields:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Medicine (internal medicine, surgery, pediatrics, obstetrics and gynecology, odonto-stomatology, laboratory, oncology, traditional medicine, nursing).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Biology (genetics, biotechnology).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Pharmacology (pharmaceutics, drug quality analysis-control, synthetic pharmaceutical chemistry, biochemistry, pharmacognosy, botany, clinical pharmacy).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- To enhance the quality of undergraduate, postgraduate education, scientifically researching and meet the necessary treatment in hospital.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Introducing the updated domestic and oversea information about science technology to promote scientific research and exchanging technology in local, other universities.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Exchanging pharmaceutical and medical information for social health developing in the Mekong Delta and Vietnam.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The object\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Postgraduate students, student of Can Tho University of Medicine and Pharmacy, scientists from schools, research institutes, hospitals, health centers, pharmaceutical companies of the Mekong Delta; other provinces and regions in Vietnam and other country.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Address\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Headquarters of Can Tho Journal of Medicine and Pharmacy, located Scientific Research and International Cooperation Office: 179 Nguyen Van Cu Street, An Khanh Ward, Ninh Kieu District, Can Tho City, Vietnam.\u003C\u002Fspan>\u003C\u002Fp>","\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Ngày 16\u002F7\u002F2015, Tạp chí Y Dược học Cần Thơ được cấp chỉ số quốc tế: ISSN 2354-1210.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 4\u002F2016, Tạp chí đã được Hội đồng Giáo sư ngành Y đưa vào danh sách các tạp chí khoa học Y học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Năm 2020 Tạp chí Y Dược học Cần Thơ đã được phê duyệt vào danh mục của các Hội đồng Giáo sư ngành Dược học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ ra 12 số\u002Fnăm, 180-200 trang\u002Fsố.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 12\u002F2022 Tạp chí Y Dược học Cần Thơ là thành viên của hệ thống Crossref và từ tháng 01\u002F2023 tạp chí thực hiện bình duyệt online kín 2 chiều nhằm tăng tính minh bạch, tin cậy của các công trình nghiên cứu khoa học và đảm bảo tốt nhất chất lượng khoa học của bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ, mục đích và phạm vi của tạp chí\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ và mục đích hoạt động của tạp chí: xuất bản nhằm mục đích phổ biến kết quả từ các đề tài nghiên cứu khoa học; giao lưu trao đổi khoa học, chia sẻ kinh nghiệm, học tập, đồng thời cập nhật thông tin khoa học mới trong các lĩnh vực y, sinh, dược học trong và ngoài nước.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phạm vi của tạp chí: Tạp chí xuất bản được chia thành 3 chuyên mục: (i) Bài báo nghiên cứu khoa học là kết quả công trình nghiên cứu khoa học có giá trị đã được triển khai nghiên cứu, (ii) Bài tổng quan y, sinh, dược học: phục vụ mục tiêu đào tạo liên tục trong lĩnh vực y, sinh, dược học; nhằm hệ thống hóa những kiến thức kinh điển và hiện đại; (iii) Thông tin cập nhật kiến thức mới về y, sinh, dược học trong nước và trên thế giới.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Chính sách truy cập mở\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ áp dụng chính sách truy cập mở đối với các bài báo đã xuất bản đến với độc giả, nhằm mở rộng cơ hội tiếp cận các kết quả nghiên cứu chất lượng cao và tăng cường trao đổi kiến thức. Tạp chí đăng tải trực tuyến (miễn phí) toàn văn các bài báo được công bố trên website của Tạp chí (https:\u002F\u002Ftapchi.ctump.edu.vn).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đạo đức xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ cam kết tuân thủ đạo đức xuất bản phù hợp với các hướng dẫn và tiêu chuẩn của the Committee on Publication Ethics (COPE), tuân thủ các nguyên tắc của COPE’s Core Practices, Best Practices Guidelines for Journal Editors và Guidelines on Good Publication Practices.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Bản thảo bài báo chỉ được chấp nhận khi được tác giả chịu trách nhiệm chính cam kết các nội dung sau: Các nội dung của bản thảo chưa được đăng tải toàn bộ hoặc một phần ở các tạp chí khác; Tất cả các tác giả đều có đóng góp một cách đáng kể vào quá trình nghiên cứu hoặc chuẩn bị bản thảo và cùng chịu trách nhiệm về các nội dung của bản thảo; Tuân thủ các biện pháp đảm bảo đạo đức nghiên cứu (ví dụ thỏa thuận đồng ý tham gia nghiên cứu).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Cam kết bảo mật\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí cam kết thực hiện và tuân thủ các quy định của luật và các văn bản hướng dẫn liên quan đến bảo mật thông tin cá nhân trên không gian mạng. Các thông tin mà người dùng (tác giả, độc giả, biên tập viên, người phản biện) nhập vào các biểu mẫu trên Hệ thống Quản lý xuất bản trực tuyến của tạp chí chỉ được sử dụng vào các mục đích đã được tuyên bố rõ ràng và sẽ không được cung cấp cho bất kỳ bên thứ ba nào khác, hay dùng vào bất kỳ mục đích nào khác.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phí gửi bài\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng bài: 1.000.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng nhanh: 1.500.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với tác giả là cán bộ viên chức thuộc Trường Đại học Y Dược Cần Thơ thì được hỗ trợ 50% lệ phí gửi đăng bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với sinh viên thực hiện đề tài nghiên cứu khoa học cấp trường được hỗ trợ 100% lệ phí đăng bài ( Tác giả gửi đính kèm “ Quyết định về việc giao tổ chức thực hiện đề tài nghiên cứu khoa học cấp Trường của sinh viên”).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Hình thức nộp lệ phí:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Tiền mặt:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Nộp trực tiếp tại Phòng Tài chính - Kế toán, Trường Đại học Y Dược Cần Thơ, số 179 Nguyễn Văn Cừ, P. An Khánh, Q. Ninh Kiều, thành phố Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Chuyển khoản:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tên Tài khoản: Trường ĐHYD Cần Thơ, Số TK: 0111000115668, tại ngân hàng Vietcombank chi nhánh Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Thời gian: Áp dụng từ ngày 01\u002F02\u002F2023.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">* Phí gửi bài không được hoàn trả khi bài viết bị từ chối hoặc tác giả xin rút bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Quy trình phản biện bài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ thực hiện quy trình phản biện kín hai chiều nghiêm ngặt. Danh tính của những người phản biện không được tiết lộ cho các tác giả và ngược lại. Quy trình thẩm định bài báo đăng gồm các bước sau:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tiếp nhận bản thảo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tác giả liên hệ gửi bản thảo đến Tạp chí qua hệ thống trực tuyến tại website: https:\u002F\u002Ftapchi.ctump.edu.vn. Hướng dẫn về cách đăng ký, gửi bài và chuẩn bị bản thảo được cung cấp trên website của Tạp chí.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sàng lọc sơ bộ\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sau khi Tòa soạn nhận được bài báo của tác giả, Ban Thư ký sẽ tiến hành kiểm tra sơ bộ bài báo (các yêu cầu về nội dung và hình thức). Những bài báo không đúng quy cách hoặc có nội dung không phù hợp hoặc vi phạm bản quyền sẽ bị từ chối (Ban Thư ký thông báo phản hồi đến tác giả trong vòng 1 tuần). Những bài báo đủ điều kiện, được Ban Thư ký tòa soạn chuyển đến Ban Biên tập có cùng chuyên môn với nội dung bài báo để đề xuất người phản biện. Thời gian kể từ khi Ban Biên tập nhận bài báo đến khi đề xuất người phản biện bài báo chậm nhất là 5 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Vòng phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký gửi bài và yêu cầu phản biện đến 02 phản biện độc lập.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Các phản biện gởi nhận xét cho Ban Thư ký. Thời gian từ khi gửi bài cho phản biện đến khi nhận ý kiến của phản biện tối đa là 20 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xử ký kết quả phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Nếu ý kiến đồng ý cho đăng và không cần chỉnh sửa, Ban Thư ký tiếp tục đăng bài theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Nếu ý kiến đồng ý đăng và cần chỉnh sửa, Ban Thư ký sẽ thông tin đến tác giả chỉnh sửa theo yêu cầu của người phản biện. Thời gian chỉnh sửa và gửi lại kéo dài không quá 2 tuần, từ khi tác giả bài báo nhận được thông tin (Quá trình này có thể lặp lại tối đa 2 lần\u002F1 bài báo). Khi có sự thống nhất, đồng ý của người phản biện; bài báo được tiếp tục đăng theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Những bài báo có chất lượng không đạt yêu cầu, cả 2 phản biện không đồng ý cho đăng sẽ bị Tòa soạn từ chối đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký tổng hợp các bản thảo đã được tác giả hoàn thiện sau thẩm định trình Ban Biên tập xem xét, Tổng Biên tập phê duyệt, quyết định bài đăng theo các tiêu chí: sự phù hợp nội dung với tôn chỉ và mục đích, thể loại bài viết (ưu tiên các bài có bài có nghiên cứu chuyên sâu, hàm lượng khoa học cao), đóng góp mới bài báo, bài báo được ưu tiên đăng trong số gần nhất của Tạp chí theo thứ tự: tính thời sự, chất lượng bài báo và thời gian gửi bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Ban Biên tập và Ban Thư ký biên tập bản thảo, chế bản, đọc rà soát lỗi. Thời gian hoàn thành từ 10-15 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Ban Thư ký có trách nhiệm thông báo cho tác giả bài báo (bằng e-mail) về tình hình phê duyệt bài báo, thời gian, số kỳ, tập xuất bản bài báo theo qui định.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">4. Danh sách bài báo theo số Tạp chí được in ấn và phát hành trong năm định kỳ được công bố chính thức trên website: https:\u002F\u002Ftapchi.ctump.edu.vn\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>",{"VOID":490},"wcQ1uqwAAAAJ","2023-05-30T08:17:21.868+00:00",[],[494],{"id":495,"createTime":28,"updateTime":28,"relativeEntities":496,"slug":28,"properties":497,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":507,"parentIds":508,"statistic":28},"6413896b-eca9-442b-a73f-182a58a0ce40",[],{"title":498,"address":501,"country":504,"abbreviation":505},{"EN":499,"VI":500},"Can Tho University of Medicine and Pharmacy","Trường Đại học Y Dược Cần Thơ",{"EN":502,"VI":503},"No 179, Nguyen Van Cu street, An Khanh ward, Ninh Kieu district, Can Tho city, Vietnam","Số 179, đường Nguyễn Văn Cừ, phường An Khánh, quận Ninh Kiều, thành phố Cần Thơ, Việt Nam",{"VOID":15},{"VOID":506},"ctump","http:\u002F\u002Fwww.ctump.edu.vn\u002F",[],[],"https:\u002F\u002Ftapchi.ctump.edu.vn\u002Findex.php\u002Fctump",{"impactFactor":32,"impactFactorByYear":512,"i10Index":32,"i10IndexLast5Year":32,"totalPublication":514,"totalPublicationByYear":515,"totalCitation":520,"totalCitationByYear":521,"totalCitationPerPublication":108,"totalCitationPerPublicationByYear":523,"hindexLast5Year":45,"hindex":45},{"2022":513,"2023":111,"2024":106},0.01,1556,{"2020":47,"2021":516,"2022":517,"2023":518,"2024":519,"2025":122},57,306,801,358,161,{"2021":146,"2022":280,"2023":522},99,{"2021":524,"2022":318,"2023":104},0.23,{"impactFactor":28,"impactFactorByYear":28,"i10Index":123,"i10IndexLast5Year":123,"totalPublication":526,"totalPublicationByYear":527,"totalCitation":526,"totalCitationByYear":528,"totalCitationPerPublication":40,"totalCitationPerPublicationByYear":531,"hindexLast5Year":49,"hindex":49},476,{"0":205,"2019":123,"2021":139,"2022":459,"2023":451,"2024":357,"2025":49,"2026":48},{"2021":42,"2022":123,"2023":161,"2024":529,"2025":360,"2026":530},136,83,{"2021":105,"2022":513,"2023":532,"2024":127,"2025":533,"2026":534},0.62,25.43,13.83,{"id":536,"createTime":537,"updateTime":382,"relativeEntities":538,"slug":539,"properties":540,"entityType":25,"verifyStatus":26,"verifyTime":28,"verifyNote":28,"languages":552,"translateLanguages":28,"viewCount":133,"subjectFields":553,"manageAffiliations":554,"indexDatabases":555,"url":556,"thumbnailPath":557,"statistic":558,"gsStatistic":594,"type":55,"analyzePriority":28},"6984a56a-db70-403b-9cc4-4013e1ceaffa","2023-05-09T06:47:40.346+00:00",[],"T%E1%BA%A1p%20ch%C3%AD%20Nghi%C3%AAn%20c%E1%BB%A9u%20n%C6%B0%E1%BB%9Bc%20ngo%C3%A0i",{"country":541,"issn":542,"title":544,"introduce":547,"gsId":550},{"VOID":15},{"VOID":543},"25252445",{"EN":545,"VI":546},"VNU Journal of Foreign Studies","Tạp chí Nghiên cứu nước ngoài",{"EN":548,"VI":549},"{\"ops\":[{\"insert\":\"\\n\\nThe \\n\"},{\"attributes\":{\"italic\":true},\"insert\":\"VNU Journal of Science\"},{\"insert\":\"\\n was established in 1985 for the publication of national and international research papers in all fields of natural sciences and technology, social sciences and humanities. 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AG",[902],"9a7c7208-b28a-42c2-a634-5a7f90eee3ab",{"id":904,"createTime":28,"updateTime":28,"relativeEntities":905,"slug":28,"properties":906,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":909,"statistic":28},"26a19206-5cad-4456-bb2f-49abd254fbc6",[],{"title":907},{"EN":908},"SPRINGER",[],[911,923],{"id":912,"indexDatabase":913,"url":918,"indexYears":28,"academicFieldIds":919,"indexDatabaseRanking":28},"121793af-1bd0-4d51-aec0-77e7bd5483fe",{"id":803,"createTime":28,"updateTime":28,"relativeEntities":914,"label":915,"description":916,"key":810,"publicationTags":917,"standard":28},[],{"EN":806,"VI":806},{"EN":808,"VI":809},[812,813],"https:\u002F\u002Fwww.scopus.com\u002Fsourceid\u002Fnull",[920,921,922],"981885c8-2d23-406a-991e-8b643dd7ab21","53866f02-5006-4f8f-a807-ec8cf950fc52","c2445d05-4773-4cac-9aeb-76edd35f4463",{"id":924,"indexDatabase":925,"url":930,"indexYears":931,"academicFieldIds":932,"indexDatabaseRanking":935},"a6ea8cb7-9f96-4666-8ed5-fd1deede7850",{"id":775,"createTime":28,"updateTime":28,"relativeEntities":926,"label":927,"description":928,"key":781,"publicationTags":929,"standard":28},[],{"EN":778,"VI":778},{"EN":778,"VI":780},[783],"https:\u002F\u002Fwww.scopus.com\u002Fsourceid\u002F21100854885","2014-2025",[933,934],"1a7c8bc3-0575-4f8d-b22c-aec346a0168a","e872d6d8-194c-4b83-9ea3-8b78dd28210d","SCOPUS__Q3",{"impactFactor":32,"impactFactorByYear":937,"i10Index":32,"i10IndexLast5Year":32,"totalPublication":218,"totalPublicationByYear":938,"totalCitation":32,"totalCitationByYear":939,"totalCitationPerPublication":32,"totalCitationPerPublicationByYear":940,"hindexLast5Year":32,"hindex":32},{},{"2013":42,"2014":146,"2015":205,"2016":199,"2017":130,"2018":128,"2019":126,"2020":145,"2021":128,"2022":127,"2023":127,"2024":40},{},{},{"meta":942,"data":944},{"total":943},"195",[945,1139,1549,1680,1788,1940,2026,2110,2233,2372],{"id":946,"createTime":947,"updateTime":948,"relativeEntities":949,"slug":950,"properties":951,"entityType":960,"verifyStatus":26,"verifyTime":961,"verifyNote":962,"languages":28,"translateLanguages":28,"viewCount":32,"primaryUrl":963,"fullTextUrl":28,"authors":964,"publicationType":1083,"publisherRelationship":1084,"citationCount":28,"citationInfo":28,"publishDate":1135,"publishYear":1136,"citationAnalyzeStatus":880,"lastCitationAnalyze":28,"indexDatabases":1137,"openAccess":28,"references":28,"isForceReanalyzing":1138},"0361b52a-9d70-4366-a412-effda6eb4ac7","2023-12-21T05:22:55.394+00:00","2025-01-29T06:00:33.773+00:00",[],"Cystic-Echinococcosis-in-the-Mediterranean",{"abstract":952,"title":954,"references":956,"doi":958},{"EN":953},"Cystic echinococcosis (CE), a zoonotic disease caused by Echinococcus granulosus sensu lato, is endemic in the Mediterranean, where pastoral activity is widespread, as the life cycle of this helminth involves sheep, as well as other livestock, as intermediate hosts. We review recent studies on CE from Mediterranean countries. Reliable data on CE, from human and animal epidemiology to treatment, remain fragmented and insufficient to gauge the magnitude of the problem beyond local communities. The lack of major advances leaves clinicians without an evidence base on which to make sound clinical decisions. Despite a wealth of publications on the subject, CE remains a neglected disease in the Mediterranean as well. Hope is seen in the establishment of a European Registry for Cystic Echinococcosis, but implementation and maintenance of such an important tool will require hard work, political commitment and resources, monetary, and otherwise.",{"EN":955},"Cystic Echinococcosis in the Mediterranean",{"VOID":957},"Deplazes P, Rinaldi L, Alvarez Rojas CA, et al. Global distribution of alveolar and cystic echinococcosis. Adv Parasitol. 2017;95:315–493.\nBudke CM, Deplazes P, Torgerson PR. Global socioeconomic impact of cystic echinococcosis. Emerg Infect Dis. 2006;12:296–303.\nCraig PS, Budke CM, Schantz PM, Tiaoying L, Qiu J, Yang Y, et al. Human echinococcosis: a neglected disease. Trop Med Health. 2007;35:283–92.\nEl Berbri I, Ducrotoy MJ, Petavy A, Fassifihri O, Shaw AP, Bouslikhane M, et al. Knowledge, attitudes and practices with regard to the presence, transmission, impact, and control of cystic echinococcosis in Sidi Kacem Province, Morocco. Infect Dis Poverty. 2015;4:48.\nBardosh KL, El Berbri I, Ducrotoy M, Bouslikhane M, Ouafaa FF, Welburn SC. Zoonotic encounters at the slaughterhouse: pathways and possibilities for the control of cystic echinococcosis in Northern Morocco. J Biosoc Sci. 2016;48(Suppl 1):S92–S115.\nBenchikh ElFegoun MC, Kohil K, L’Ollivier C, Lleu M, Babelhadj B, Piarroux M, et al. Targeting abattoirs to control cystic echinococcosis in Algeria. Bull Soc Pathol Exot. 2016;109:192–4.\nChaâbane-Banaoues R, Oudni-M’rad M, M’rad S, Mezhoud H, Babba H. Environmental contamination by Echinococcus granulosus sensu lato eggs in relation to slaughterhouses in urban and rural areas in Tunisia. Korean J Parasitol. 2016;54:113–8.\nDucrotoy MJ, Yahyaoui Azami H, El Berbri I, Bouslikhane M, Fassi Fihri O, Boué F, et al. Integrated health messaging for multiple neglected zoonoses: approaches, challenges and opportunities in Morocco. Acta Trop. 2015;152:17–25.\nBudke CM, Casulli A, Kern P, Vuitton DA. Cystic and alveolar echinococcosis: successes and continuing challenges. PLoS Negl Trop Dis. 2017;11:e0005477.\nAkalin S, Kutlu SS, Caylak SD, Onal O, Kaya S, Bozkurt AI. Seroprevalence of human cystic echinococcosis and risk factors in animal breeders in rural communities in Denizli, Turkey. J Infect Dev Ctries. 2014;8:1188–94.\n•• Chebli H, Laamrani El Idrissi A, Benazzouz M, et al. Human cystic echinococcosis in Morocco: ultrasound screening in the Mid Atlas through an Italian-Moroccan partnership. PLoS Negl Trop Dis. 2017;11:e0005384. This paper reports the findings of a US survey conducted in Morocco, showing that such surveys are extremely useful to assess the local burden of CE and its public health relevance.\nRomero-Alegria A, Belhassen-García M, Alonso-Sardón M, Velasco-Tirado V, Lopez-Bernus A, Carpio-Pérez A, Bellido JLM, Muro A, Cordero M, Pardo-Lledias J (2017) Imported cystic echinococcosis in western Spain: a retrospective study. Trans R Soc Trop Med Hyg 664–669.\nBelhassen-García M, Romero-Alegria A, Velasco-Tirado V, Alonso-Sardón M, Lopez-Bernus A, Alvela-Suarez L, et al. Study of hydatidosis-attributed mortality in endemic area. PLoS One. 2014;9:e91342.\nAmado-diago CA, Gutiérrez-cuadra M, Armi C (2015) Echinococcosis: a 15-year epidemiological, clinical and outcome overview. Rev Clin Esp 14–18.\nHerrador Z, Siles-Lucas M, Aparicio P, Lopez-Velez R, Gherasim A, Garate T, Benito A. Cystic echinococcosis epidemiology in spain based on hospitalization records, 1997-2012. PLoS Negl Trop Dis. 2016;10:e0004942.\nLopez-Bernus A, Belhassen-García M, Alonso-Sardón M, Carpio-Perez A, Velasco-Tirado V, Romero-Alegria Á, et al. Surveillance of human echinococcosis in Castilla-Leon (Spain) between 2000-2012. PLoS Negl Trop Dis. 2015;9:e0004154.\nLopez-Bernus A, Belhassen-García M, Carpio-Perez A, Perez Del Villar L, Romero-Alegria A, Velasco-Tirado V, et al. Is cystic echinoccocosis re-emerging in western Spain? Epidemiol Infect. 2015;143:3351–7.\nCarabin H, Balsera-Rodríguez FJ, Rebollar-Sáenz J, Benner CT, Benito A, Fernández-Crespo JC, et al. Cystic echinococcosis in the Province of Álava, North Spain: the monetary burden of a disease no longer under surveillance. PLoS Negl Trop Dis. 2014;8:e3069.\nNarra R, Maestri M, Budke CM, Tamarozzi F, Mariconti M, Nicoletti GJ, et al. Costs associated with surgically treated cases of abdominal cystic echinococcosis: a single center’s experience from 2008 to 2014, Pavia, Italy. Am J Trop Med Hyg. 2016;95:405–9.\nZammarchi L, Vellere I, Stella L, Bartalesi F, Strohmeyer M, Bartoloni A. Spectrum and burden of neglected tropical diseases observed in an infectious and tropical diseases unit in Florence, Italy (2000-2015). Intern Emerg Med. 2017;12:467–77.\nBrundu D, Piseddu T, Stegel G, Masu G, Ledda S, Masala G. Acta tropica retrospective study of human cystic echinococcosis in Italy based on the analysis of hospital discharge records between 2001 and 2012. Acta Trop. 2014;140:91–6.\nTamarozzi F, Mariconti M, Casulli A, Magnino S, Brunetti E. Comment on: retrospective study of human cystic echinococcosis in Italy based on the analysis of hospital discharge records between 2001 and 2012. Acta Trop. 2015;144:50–1.\nvan Cauteren D, Millon L, de Valk H, Grenouillet F. Retrospective study of human cystic echinococcosis over the past decade in France, using a nationwide hospital medical information database. Parasitol Res. 2016;115:4261–5.\nBrundu D, Piseddu T, Stegel G, Masu G, Ledda S, Masala G. Response to comment on: retrospective study of human cystic echinococcosis in Italy based on the analysis of hospital discharge records between 2001 and 2012. Acta Trop. 2015;144:52.\nBen-Shimol S, Sagi O, Houri O, Bazarsky E, Berkowitz A, Bulkowstein S, et al. Cystic echinococcosis in Southern Israel. Acta Parasitol. 2016;61:178–86.\nMor N, Diken Allahverdi T, Anuk T. The situation of cystic echinococcoses in Kars State Hospital for the last five years. Turk Parazitol Derg. 2015;39:108–11.\nTürkoğlu E, Demirtürk N, Tünay H, Akıcı M, Öz G, Baskin Embleton D. Evaluation of patients with cystic echinococcosis. Turk Parazitol Derg. 2017;41:28–33.\nAkcam AT, Ulku A, Koltas IS, et al. Clinical characterization of unusual cystic echinococcosis in southern part of Turkey. Ann Saudi Med. 2014;34:508–16.\nLianos GD, Lazaros A, Vlachos K, et al. Unusual locations of hydatid disease: a 33 year’s experience analysis on 233 patients. Updat Surg. 2015;67:279–82.\nKuzucu A, Ulutas H, Reha Celik M, Yekeler E. Hydatid cysts of the lung: lesion size in relation to clinical presentation and therapeutic approach. Surg Today. 2014;44:131–6.\nCetinkol Y, Enginyurt Ö, Çelebi B, Yıldırım AA, Çankaya S, Aktepe OC. Investigation of zoonotic infections in risk groups in Ordu University Hospital, Turkey. Niger J Clin Pract. 2017;20:6–11.\nGültepe B, Dülger AC, Gültepe İ, Karadas S, Ebinç S, Esen R. Higher seroprevalence of hepatitis B virus antigen in patients with cystic hydatid disease than in patients referred to internal medicine clinics in Turkey. Korean J Parasitol. 2014;52:47–9.\nHassanain MA, Shaapan RM, Khalil FAM. Sero-epidemiological value of some hydatid cyst antigen in diagnosis of human cystic echinococcosis. J Parasit Dis. 2016;40:52–6.\nTorgerson PR, Deplazes P. Echinococcosis: diagnosis and diagnostic interpretation in population studies. Trends Parasitol. 2009;25:164–70.\nMacpherson CN, Romig T, Zeyhle E, Rees PH, Were JB. Portable ultrasound scanner versus serology in screening for hydatid cysts in a nomadic population. Lancet (London, England). 1987;2:259–61.\nMacpherson CNL, Kachani M, Lyagoubi M, Berrada M, Shepherd M, Fields PF, et al. Cystic echinococcosis in the Berber of the Mid Atlas mountains, Morocco: new insights into the natural history of the disease in humans. Ann Trop Med Parasitol. 2004;98:481–90.\nRossi P, Tamarozzi F, Galati F, et al. The first meeting of the European Register of Cystic Echinococcosis (ERCE). Parasit Vectors. 2016;9:243.\n•• Tamarozzi F, Rossi P, Galati F, Mariconti M, Nicoletti GJ, Rinaldi F, et al. The Italian registry of cystic echinococcosis (RIEC): the first prospective registry with a European future. Euro Surveill. 2015;20:1–6. This paper reported on the institution of the first prospective registry of CE cases worldwide.\nConchedda M, Seu V, Capra S, Caredda A, Pani SP, Lochi PG, et al. A study of morphological aspects of cystic echinococcosis in sheep in Sardinia. Acta Trop. 2016;159:200–10.\nUmhang G, Richomme C, Hormaz V, Boucher J, Boué F. Acta tropica pigs and wild boar in Corsica harbor Echinococcus canadensis G6\u002F7 at levels of concern for public health and local economy. Acta Trop. 2014;133:64–8.\nAbbas I. Molecular and epidemiological updates on cystic echinococcosis infecting water buffaloes from Egypt. Vet World. 2016;9:1355–63.\nChaligiannis I, Maillard S, Boubaker G, Spiliotis M, Saratsis A, Gottstein B, et al. Echinococcus granulosus infection dynamics in livestock of Greece. Acta Trop. 2015;150:64–70.\nLahmar S, Boufana B, Jebabli L, Craig PS, Ayari H, Basti T, et al. Modelling the transmission dynamics of cystic echinococcosis in donkeys of different ages from Tunisia. Vet Parasitol. 2014;205:119–24.\nKostopoulou D, Claerebout E, Arvanitis D, Ligda P, Voutzourakis N, Casaert S, et al. Abundance, zoonotic potential and risk factors of intestinal parasitism amongst dog and cat populations: the scenario of Crete, Greece. Parasit Vectors. 2017;10:43.\nDore F, Varcasia A, Pipia AP, Sanna G, Parpaglia MLP, Corda A, et al. Veterinary parasitology ultrasound as a monitoring tool for cystic echinococcosis in sheep. Vet Parasitol. 2014;203:59–64.\nHussein HA, Elrashidy M. Ultrasonographic features of the liver with cystic echinococcosis in sheep. Vet Rec Open. 2014;1:e000004.\nSagkan-Ozturk A, Durgut R, Ozturk OH. Oxidant\u002Fantioxidant status in lambs and sheep with liver and lung cystic echinococcosis diagnosed by ultrasonography and necropsy. Vet Parasitol. 2015;208:280–5.\nAbdel-Moein KA, Hamza DA. Norway rat (Rattus norvegicus) as a potential reservoir for Echinococcus granulosus: a public health implication. Acta Parasitol. 2016;61:815–9.\nCassini R, Mulatti P, Zanardello C, Simonato G, Signorini M, Cazzin S, et al. Retrospective and spatial analysis tools for integrated surveillance of cystic echinococcosis and bovine cysticercosis in hypo-endemic areas. Geospat Health. 2014;8:509–15.\nScala A, Bosco A, Pipia AP, et al. Cystic echinococcosis in cattle dairy farms: spatial distribution and epidemiological dynamics. Geospat Health. 2017;12:562.\n•• Kinkar L, Laurimäe T, Simsek S, et al. High-resolution phylogeography of zoonotic tapeworm Echinococcus granulosus sensu stricto genotype G1 with an emphasis on its distribution in Turkey, Italy and Spain. Parasitology. 2016;143:1790–801. This paper emphasizes the great genetic diversity of G1 CE specimens, suggesting that the infection could spread both geographically and to other intermediate hosts.\nDi Paolo A, Piseddu T, Sebastianelli M, Manuali E, Corneli S, Paniccià M, et al. Detection of Echinococcus granulosus G3 in a Wild Boar (Sus scrofa) in Central Italy using PCR and sequencing. J Wildl Dis. 2017;53:399–401.\nAlam-Eldin YH, Abdel Aaty HE, Ahmed MA. Molecular characterization of cystic echinococcosis: first record of G7 in Egypt and G1 in Yemen. Acta Parasitol. 2015;60:662–5.\nBakal U, Simsek S, Kazez A. Surgical and molecular evaluation of pediatric hydatid cyst cases in Eastern Turkey. Korean J Parasitol. 2015;53:785–8.\nGori F, Armua-Fernandez MT, Milanesi P, Serafini M, Magi M, Deplazes P, et al. The occurrence of taeniids of wolves in Liguria (Northern Italy). Int J Parasitol Parasites Wildl. 2015;4:252–5.\nPoglayen G, Gori F, Morandi B, et al. Italian wolves (Canis lupus italicus Altobello, 1921) and molecular detection of taeniids in the Foreste Casentinesi National Park, Northern Italian Apennines. Int J Parasitol Parasites Wildl. 2017;6:1–7.\nRoinioti E, Papathanassopoulou A, Theodoropoulou I, Simsek S, Theodoropoulos G. Molecular identification of Echinococcus granulosus isolates from ruminants in Greece. Vet Parasitol. 2016; https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.vetpar.2016.06.040.\n•• Kinkar L, Laurimäe T, Sharbatkhori M, et al. New mitogenome and nuclear evidence on the phylogeny and taxonomy of the highly zoonotic tapeworm Echinococcus granulosus sensu stricto. Infect Genet Evol. 2017;52:52–8. This paper used nuclear genomic markers to analyze CE specimens suggesting that the G2 genotype should no longer be considered as valid.\nBoufana B, Lett W, Lahmar S, et al. Canine echinococcosis: genetic diversity of Echinococcus granulosus sensu stricto (s.s.) from definitive hosts. J Helminthol. 2015;89:689–98.\nBoufana B, Lahmar S, Rebaï W, Ben Safta Z, Jebabli L, Ammar A, et al. Genetic variability and haplotypes of Echinococcus isolates from Tunisia. Trans R Soc Trop Med Hyg. 2014;108:706–14.\nZait H, Kouidri M, Grenouillet FE, Umhang G, Millon L, Hamrioui B, et al. Molecular characterization of Echinococcus granulosus sensu stricto and Echinococcus canadensis in humans and livestock from Algeria. Parasitol Res. 2016;115:2423–31.\nLissandrin R, Tamarozzi F, Piccoli L, Tinelli C, De Silvestri A, Mariconti M, et al. Factors influencing the serological response in hepatic Echinococcus granulosus infection. Am J Trop Med Hyg. 2016;94:166–71.\nCarmena D, Benito A, Eraso E. Antigens for the immunodiagnosis of Echinococcus granulosus infection: an update. Acta Trop. 2006;98:74–86.\nPagnozzi D, Addis MF, Biosa G, et al. Diagnostic accuracy of antigen 5-based ELISAs for human cystic echinococcosis. PLoS Negl Trop Dis. 2016;10:e0004585.\nPagnozzi D, Biosa G, Addis MF, Mastrandrea S, Masala G, Uzzau S. An easy and efficient method for native and immunoreactive Echinococcus granulosus antigen 5 enrichment from hydatid cyst fluid. PLoS One. 2014; https:\u002F\u002Fdoi.org\u002F10.1371\u002Fjournal.pone.0104962.\nBoubaker G, Gottstein B, Hemphill A, Babba H, Spiliotis M. Echinococcus P29 antigen: molecular characterization and implication on post-surgery follow-up of CE patients infected with different species of the Echinococcus granulosus complex. PLoS One. 2014; https:\u002F\u002Fdoi.org\u002F10.1371\u002Fjournal.pone.0098357.\nStojkovic M, Adt H-M, Rosenberger K, Boubaker G, Hernandez-Gonzalez A, Junghanss T, et al. Follow-up of surgically treated patients with cystic echinococcosis: can novel recombinant antigens compete with imaging? Analysis of a patient cohort. Tropical Med Int Health. 2017;22:614–21.\nTamarozzi F, Mariconti M, Covini I, Brunetti E. Rapid diagnostic tests for the serodiagnosis of human cystic echinococcosis. Bull Soc Pathol Exot. 2017;110:20–30.\n• Tamarozzi F, Covini I, Mariconti M, et al. Comparison of the diagnostic accuracy of three rapid tests for the serodiagnosis of hepatic cystic echinococcosis in humans. PLoS Negl Trop Dis. 2016;10:1–13. This paper tested the effectivness of RDTs for the serological confirmation of CE cases, proving that RDTs are reliable to use.\nTamer GS, Dündar D, Uzuner H, Baydemir C. Evaluation of immunochromatographic test for the detection of antibodies against echinococcosis granulosus. Med Sci Monit. 2015;21:1219–22.\nKoken D, Cagli B, Tuncel SA, Sengul E, Yilmaz E, Unlu ME. Efficacy of diffusion-weighted MRI in the differentiation of all liver hydatid cyst types. J Med Imaging Radiat Oncol. 2016;60:59–65.\nStojkovic M, Rosenberger K, Kauczor HU, Junghanss T, Hosch W. Diagnosing and staging of cystic echinococcosis: how do CT and MRI perform in comparison to ultrasound? PLoS Negl Trop Dis. 2012;6:1–8.\nSolomon N, Fields PJ, Tamarozzi F, Brunetti E, Macpherson CNL. Expert reliability for the world health organization standardized ultrasound classification of cystic echinococcosis. Am J Trop Med Hyg. 2017;96:686–91.\nSolomon N, Kachani M, Zeyhle E, Macpherson CNL. The natural history of cystic echinococcosis in untreated and albendazole-treated patients. Acta Trop. 2017;171:52–7.\nGottstein B, Wang J, Blagosklonov O, Grenouillet F, Millon L, Vuitton DA, et al. Echinococcus metacestode: in search of viability markers. Parasite. 2014;21:63.\nPetrone L, Vanini V, Petruccioli E, et al. IL-4 specific-response in whole blood associates with human cystic echinococcosis and cyst activity. J Inf Secur. 2015;70:299–306.\nVismarra A, Mangia C, Passeri B, Brundu D, Masala G, Ledda S, et al. Immuno-histochemical study of ovine cystic echinococcosis (Echinococcus granulosus) shows predominant T cell infiltration in established cysts. Vet Parasitol. 2015;209:285–8.\nTurhan N, Esendagli G, Ozkayar O, Tunali G, Sokmensuer C, Abbasoglu O. Co-existence of Echinococcus granulosus infection and cancer metastasis in the liver correlates with reduced Th1 immune responses. Parasite Immunol. 2015;37:16–22.\nMariconti M, Meroni V, Badulli C, Brunetti E, Tinelli C, De Silvestri A, et al. Correlation of serum sHLA-G levels with cyst stage in patients with cystic echinococcosis: is it an immune evasion strategy? Parasite Immunol. 2016;38:414–8.\n•• Siles-Lucas M, Sánchez-Ovejero C, González-Sánchez M, González E, Falcón-Pérez JM, Boufana B, et al. Isolation and characterization of exosomes derived from fertile sheep hydatid cysts. Vet Parasitol. 2017;236:22–33. This paper proved the existence of exosomes in E. granulosus , thus opening new possibilities for the detection of potential biological markers.\nZeghir-Bouteldja R, Polomé A, Bousbata S, Touil-Boukoffa C. Comparative proteome profiling of hydatid fluid from Algerian patients reveals cyst location-related variation in Echinococcus granulosus. Acta Trop. 2017;171:199–206.\nBrunetti E, Garcia HH, Junghanss T. Cystic echinococcosis: chronic, complex, and still neglected. PLoS Negl Trop Dis. 2011;5:3–7.\nBrunetti E, Kern P, Vuitton DA. Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans. Acta Trop. 2010;114:1–16.\nJunghanss T, da Silva AM, Horton J, Chiodini PL, Brunetti E. Clinical management of cystic echinococcosis: state of the art, problems, and perspectives. Am J Trop Med Hyg. 2008;79:301–11.\nCirilli R, Guglielmi P, Formica FR, Casulli A, Carradori S. The sodium salt of the enantiomers of ricobendazole: preparation, solubility and chiroptical properties. J Pharm Biomed Anal. 2017;139:1–7.\nFerretti R, Carradori S, Guglielmi P, Pierini M, Casulli A, Cirilli R. Enantiomers of triclabendazole sulfoxide: analytical and semipreparative HPLC separation, absolute configuration assignment, and transformation into sodium salt. J Pharm Biomed Anal. 2017;140:38–44.\nAmri M, Touil-Boukoffa C. A protective effect of the laminated layer on Echinococcus granulosus survival dependent on upregulation of host arginase. Acta Trop. 2015;149:186–94.\nAmri M, Touil-Boukoffa C. In vitro anti-hydatic and immunomodulatory effects of ginger and [6]-gingerol. Asian Pac J Trop Med. 2016;9:749–56.\nLabsi M, Khelifi L, Mezioug D, Soufli I, Touil-Boukoffa C. Antihydatic and immunomodulatory effects of Punica granatum peel aqueous extract in a murine model of echinococcosis. Asian Pac J Trop Med. 2016;9:211–20.\nAli NM, Ibrahim AN, Ahmed NS. Assessment of the effect of Allium sativum on serum nitric oxide level and hepatic histopathology in experimental cystic echinococcosis in mice. J Parasit Dis. 2016;40:893–900.\nKahriman G, Ozcan N, Dogan S, Karaborklu O. Percutaneous treatment of liver hydatid cysts in 190 patients: a retrospective study. Acta Radiol. 2017;58:676–84.\nArslan S, Bakdik S, Oncu F, Tolu I, Eryilmaz MA. Successful percutaneous treatment of extrahepatic cystic echinococcosis through PAIR and single puncture catheter techniques. Jpn J Radiol. 2017;35:296–302.\nÖzdil B, Keçe C, Ünalp ÖV. An alternative method for percutaneous treatment of hydatid cysts: PAI technique. Turk Parazitol Derg. 2016;40:77–81.\nMert K, Erol B, Cemil G, Yunus C, Şü A, Kale B, Toslak İE, Akhan O (2014) Hepatic cystic echinococcosis: percutaneous treatment as an outpatient procedure. Asian Pac J Trop Med. 212–215.\nÖrmeci N (2014) PAIR vs Örmeci technique for the treatment of hydatid cyst. Turk J Gastroentero 2014:358–364.\nAkhan O, Salik AE, Ciftci T, Akinci D, Islim F, Akpinar B. Comparison of long-term results of percutaneous treatment techniques for hepatic cystic echinococcosis types 2 and 3b. AJR Am J Roentgenol. 2017;208:878–84.\nRinaldi F, De Silvestri A, Tamarozzi F, Cattaneo F, Lissandrin R, Brunetti E (2014) Medical treatment versus “ Watch and Wait ” in the clinical management of CE3b echinococcal cysts of the liver. 1–7.\nAkkucuk S, Aydogan A, Ugur M, Yetim I, Davran R, Oruc C, et al. Comparison of surgical procedures and percutaneous drainage in the treatment of liver hydatide cysts: a retrospective study in an endemic area. Int J Clin Exp Med. 2014;7:2280–5.\nSevinç B, Karahan Ö, Şimşek G, Bakdık S, Aksoy N, Soydan S. (2016) Role of different treatment modalities in cavity volume during the treatment of cystic ecchinococcosis Turkiye Parazitol Derg. 2016 40(2)63–66.\nAlam-Eldin YH, Badawy AF. Destructive effect of gamma irradiation on Echinococcus granulosus metacestodes. Parasitol Res. 2015;114:3145–50.\nTamarozzi F, Vuitton L, Brunetti E, Vuitton DA, Koch S. Non-surgical and non-chemical attempts to treat echinococcosis: do they work? Parasite. 2014;21:75.\nBenkabbou A, Souadka A, Serji B, Hachim H. Changing paradigms in the surgical management of cystic liver hydatidosis improve the postoperative outcomes. Surgery. 2013;159:1170–80.",{"VOID":959},"10.1007\u002Fs40475-017-0129-z","PUBLICATION","2025-01-29T06:00:33.772+00:00","Auto Verify","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs40475-017-0129-z",[965,999,1019,1032,1054],{"id":966,"sortIndex":32,"researcher":28,"roles":967,"affiliations":969,"properties":996,"displayName":998,"givenName":28,"familyName":28},"4f62cf4a-8d14-49e1-911f-36d151121b8f",[968],"AUTHOR",[970,978,987],{"id":971,"sortIndex":32,"affiliation":972,"properties":28},"11d2b5a6-3162-4af9-a35b-1e1a892cd063",{"id":971,"createTime":28,"updateTime":28,"relativeEntities":973,"slug":28,"properties":974,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":977,"statistic":28},[],{"title":975},{"VI":976},"PhD School of Experimental Medicine, University of Pavia, Pavia, Italy",[],{"id":979,"sortIndex":40,"affiliation":980,"properties":986},"dca91b8e-bd4e-4d11-8236-68c1140f0f75",{"id":979,"createTime":28,"updateTime":28,"relativeEntities":981,"slug":28,"properties":982,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":985,"statistic":28},[],{"title":983},{"VI":984},"WHO—IWGE Collaborating Center for Clinical Management of Cystic Echinococcosis, San Matteo Hospital Foundation, Pavia, Italy",[],{},{"id":988,"sortIndex":123,"affiliation":989,"properties":995},"e49df0ae-26a6-4afc-8996-00ef11184765",{"id":988,"createTime":28,"updateTime":28,"relativeEntities":990,"slug":28,"properties":991,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":994,"statistic":28},[],{"title":992},{"VI":993},"Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy",[],{},{"title":997},{"VI":998},"Tommaso Manciulli",{"id":1000,"sortIndex":40,"researcher":28,"roles":1001,"affiliations":1002,"properties":1016,"displayName":1018,"givenName":28,"familyName":28},"da8be6b3-790f-475e-ad79-e9b968cc4b1d",[968],[1003,1009],{"id":979,"sortIndex":32,"affiliation":1004,"properties":28},{"id":979,"createTime":28,"updateTime":28,"relativeEntities":1005,"slug":28,"properties":1006,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1008,"statistic":28},[],{"title":1007},{"VI":984},[],{"id":988,"sortIndex":40,"affiliation":1010,"properties":1015},{"id":988,"createTime":28,"updateTime":28,"relativeEntities":1011,"slug":28,"properties":1012,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1014,"statistic":28},[],{"title":1013},{"VI":993},[],{},{"title":1017},{"VI":1018},"M. 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Lissandrin",{"id":1055,"sortIndex":45,"researcher":28,"roles":1056,"affiliations":1057,"properties":1080,"displayName":1082,"givenName":28,"familyName":28},"0341ad30-9569-4127-a7b7-fe5cc082dbcd",[968],[1058,1064,1073],{"id":979,"sortIndex":32,"affiliation":1059,"properties":28},{"id":979,"createTime":28,"updateTime":28,"relativeEntities":1060,"slug":28,"properties":1061,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1063,"statistic":28},[],{"title":1062},{"VI":984},[],{"id":1065,"sortIndex":40,"affiliation":1066,"properties":1072},"c9f755d3-0ede-4f00-aec8-f4e51e5ec7d1",{"id":1065,"createTime":28,"updateTime":28,"relativeEntities":1067,"slug":28,"properties":1068,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1071,"statistic":28},[],{"title":1069},{"VI":1070},"Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy",[],{},{"id":1043,"sortIndex":123,"affiliation":1074,"properties":1079},{"id":1043,"createTime":28,"updateTime":28,"relativeEntities":1075,"slug":28,"properties":1076,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1078,"statistic":28},[],{"title":1077},{"VI":1048},[],{},{"title":1081},{"VI":1082},"E. 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There is a contrast between French Guiana, where the incidence of this disease is the highest in the world, and other countries where this disease is practically non-existent. Recent findings are essentially in French Guiana where a unique strain MST17 has been identified; it is probably more virulent than those usually found with a particularly marked pulmonary tropism, a mysterious animal reservoir, a geographical distribution that raises questions. Q fever is a bacterial zoonosis due to Coxiella burnetii that has been reported worldwide. On the Guiana Shield, a region mostly covered by Amazonian forest, which encompasses the Venezuelan State of Bolivar, Guyana, Suriname, French Guiana, and the Brazilian State of Amapá, the situation is very heterogeneous. While French Guiana is the region reporting the highest incidence of this disease in the world, with a single infecting clone (MST 117) and a unique epidemiological cycle, it has hardly ever been reported in other countries in the region. This absence of cases raises many questions and is probably due to massive under-diagnosis. Studies should estimate comprehensively the true burden of this disease in the region.","Trong bài tổng quan này, chúng tôi báo cáo về tình trạng hiểu biết về bệnh Q ở người tại Brazil và trên nền tảng Guiana, một khu vực Amazon nằm ở phía đông bắc Nam Mỹ. Có một sự tương phản giữa Guiana thuộc Pháp, nơi mà tỷ lệ mắc bệnh này cao nhất thế giới, và các quốc gia khác, nơi bệnh này hầu như không tồn tại. Những phát hiện gần đây chủ yếu diễn ra ở Guiana thuộc Pháp, nơi đã xác định được một chủng vi khuẩn độc nhất MST17; có lẽ nó gây bệnh mạnh hơn so với những chủng thường thấy với tính ưu việt rõ rệt về tropism phổi, một nguồn dự trữ động vật bí ẩn, và sự phân bố địa lý cần được xem xét thêm. Bệnh Q là một bệnh truyền nhiễm do vi khuẩn Coxiella burnetii gây ra đã được báo cáo trên toàn cầu. Tại nền tảng Guiana, một khu vực chủ yếu được bao phủ bởi rừng Amazon, bao gồm tiểu bang Bolivar của Venezuela, Guyana, Suriname, Guiana thuộc Pháp, và tiểu bang Amapá của Brazil, tình hình rất đa dạng. Trong khi Guiana thuộc Pháp là khu vực có tỷ lệ mắc bệnh cao nhất trên thế giới, với một clone duy nhất gây nhiễm (MST 117) và một chu trình dịch tễ học độc nhất, thì bệnh này hầu như không bao giờ được báo cáo ở các quốc gia khác trong khu vực. Sự vắng mặt của các trường hợp này đặt ra nhiều câu hỏi và có thể do sự chẩn đoán thiếu sót nghiêm trọng. Các nghiên cứu nên ước tính toàn diện gánh nặng thực sự của bệnh này trong khu vực.",{"EN":1150,"VI":1151},"Human Q Fever on the Guiana Shield and Brazil: Recent Findings and Remaining Questions","Căn Bệnh Q Ở Người Trên Nền Tảng Guiana và Brazil: Những Phát Hiện Gần Đây và Những Câu Hỏi Còn Đọng Lại",{"VI":1153},"Bệnh Q, Guiana, Brazil, Coxiella burnetii, dịch tễ học, zoonosis",{"VOID":1155},"Eldin C, Melenotte C, Mediannikov O, Ghigo E, Million M, Edouard S, et al. From Q fever to Coxiella burnetii infection: a paradigm change. Clin Microbiol Rev. 2017;30(1):115–90.\nMillion M, Lepidi H, Raoult D. Fièvre Q: actualités diagnostiques et thérapeutiques. Med Mal Infect. 2009;39(2):82–94.\nSchimmer B, Morroy G, Dijkstra F, Schneeberger PM, Weers-Pothoff G, Timen A, et al. Large ongoing Q fever outbreak in the south of The Netherlands, 2008. Euro Surveill. 2008;13(31).\nMillion M, Raoult D. No such thing as chronic Q fever. Emerg Infect Dis. 2017;23(5):856–7.\nKampschreur LM, Wegdam-Blans MC, Wever PC, Renders NH, Delsing CE, Sprong T, et al. Chronic Q fever diagnosis- consensus guideline versus expert opinion. Emerg Infect Dis. 2015;21(7):1183–8.\nRaoult D. Chronic Q fever: expert opinion versus literature analysis and consensus. J Inf Secur. 2012;65(2):102–8.\nFloch H. La pathologie vétérinaire en Guyane française (les affections des porcins, des caprins et des ovins). Rev Elev Med Vet Pays Trop. 1955;8:11–3.\nFloch H, Fièvre Q. Rapport sur le fonctionnement technique de l'Institut Pasteur de la Guyane française en 1952. Archives de l'Institut Pasteur de la Guyane française. 1954;328(5).\nPfaff F, Francois A, Hommel D, Jeanne I, Margery J, Guillot G, et al. Q fever in French Guiana: new trends. Emerg Infect Dis. 1998;4(1):131–2.\nFrançois A, Pfaff P, Hommel D, Fouquet E, Favre J, Jeanne I, et al. Fièvre Q en Guyane : une épidémiologie particulière. Bulletin Epidémiologique Hebdomadaire. 1997;35:5–8.\nGardon J, Heraud JM, Laventure S, Ladam A, Capot P, Fouquet E, et al. Suburban transmission of Q fever in French Guiana: evidence of a wild reservoir. J Infect Dis. 2001;184(3):278–84.\nGrangier C, Debin M, Ravachol V, Ardillon V, Queuche F, Simonnet C, et al., editors. Étude rétrospective de la fièvre Q en Guyane de 1950 à 2006 et mise en place d’un système de surveillance. Actualités du Pharo, IMTSSA, Marseille; 2007; Marseille, France.\n• Thill P, Beillard E, Bisser S, Berlioz-Arthaud A, Nacher M, Djossou F, et al., editors. High endemicity of Q fever in French Guiana, Latin America: a cross-sectional study 2009-2017. 29th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID); 2019 13 – 16 April 2019; Amsterdam, Netherlands. This study, in press, shows the stability of incidence of Q fever in French Guiana, traducing a state of hyperendemicity.\nEldin C, Mahamat A, Demar M, Abboud P, Djossou F, Raoult D. Q fever in French Guiana. Am J Trop Med Hyg. 2014;91(4):771–6.\nEdouard S, Mahamat A, Demar M, Abboud P, Djossou F, Raoult D. Comparison between emerging Q fever in French Guiana and endemic Q fever in Marseille. France Am J Trop Med Hyg. 2014;90(5):915–9.\nBritish Thoracic Society (BTS). Guidelines for the management of community acquired pneumonia in adults. Thorax. 2001;56(Suppl 4):IV1–64.\nEpelboin L, Chesnais C, Boulle C, Drogoul AS, Raoult D, Djossou F, et al. Q fever pneumonia in French Guiana: prevalence, risk factors, and prognostic score. Clin Infect Dis. 2012;55(1):67–74.\nSanderink D, Melenotte C, Walter G, Bidaud B, Jaureguiberry S, Mahamat A, et al., editors. La fièvre Q chronique en Guyane française : une entité méconnue (MIG-15). 18èmes Journées Nationales d’Infectiologie (JNI); 2017 21-23 juin 2017; Saint-Malo, France.\nEpelboin L, Mahamat A, Bonifay T, Demar M, Abboud P, Walter G, et al. Q fever among community-acquired pneumonia in French Guiana: still the highest prevalence in the world. Case control study 2008-2012 and comprehensive review of the literature. Travel Med Infect Dis. 2020;In press.\n•• Flamand C, Hozé N, Bailly S, Zhu-Soubise A, Mbouangoro A, Fritzell C, et al., editors. Étude de la dynamique de la transmission de la fièvre Q en Guyane à partir de données sérologiques. Premières journées Guyanaises d'Infectiologie; 2020; Cayenne, French Guiana. This study, in press, shows that the distribution of seroprevalence in French Guiana is not correlated with the regions or ethnic groups usually affected by Q fever.\nVaz T, Mahamat A, Demar M, Bourbigot A, Raoult D, Djossou F. Coxiella burnetti est-il l’agent de la fièvre Q en Guyane ? 8èmes Journées Nationales d'Infectiologie. 2007.\nPommier de Santi V, Briolant S, Mahamat A, Ilcinkas C, Blanchet D, de Thoisy B, et al. Q fever epidemic in Cayenne, French Guiana, epidemiologically linked to three-toed sloth. Comp Immunol Microbiol Infect Dis. 2018;56:34–8.\nChristen JR, Edouard S, Lamour T, Martinez E, Rousseau C, de Laval F, et al. Capybara and brush cutter involvement in Q fever outbreak in remote area of Amazon Rain Forest, French Guiana, 2014. Emerg Infect Dis. 2020;26(5):993–7.\nRaoult D, Stein A. Q fever during pregnancy--a risk for women, fetuses, and obstetricians. N Engl J Med. 1994;330(5):371.\nAmit S, Shinar S, Halutz O, Atiya-Nasagi Y, Giladi M. Suspected person-to-person transmission of Q fever among hospitalized pregnant women. Clin Infect Dis. 2014;58(11):e146–7.\nDavoust B, Marie JL. Pommier de Santi V, Berenger JM, Edouard S, Raoult D. Three-toed sloth as putative reservoir of Coxiella burnetii, Cayenne, French Guiana. Emerg Infect Dis. 2014;20(10):1760–1.\nPommier de Santi V, Marié J-L, Briolant S, Mahamat A, Djossou F, Epelboin L, et al. Spécificités épidémiologiques de la fièvre Q en Guyane. Bull Acad Vét France. 2016;169(2):148–54.\nMahamat A, Edouard S, Demar M, Abboud P, Patrice JY, La Scola B, et al. Unique clone of Coxiella burnetii causing severe Q fever. French Guiana Emerg Infect Dis. 2013;19(7):1102–4.\nD’Amato F, Eldin C, Georgiades K, Edouard S, Delerce J, Labas N, et al. Loss of TSS1 in hypervirulent Coxiella burnetii 175, the causative agent of Q fever in French Guiana. Comp Immunol Microbiol Infect Dis. 2015;41:35–41.\nEldin C, Perreal C, Mahamat A, Djossou F, Edouard S, Raoult D. Antibiotic susceptibility determination for six strains of Coxiella burnetii MST 17 from Cayenne. French Guiana Int J Antimicrob Agents. 2015;46(5):600–2.\nDubois F, Pasquier J, Thill P, Blaise N, Djossou F, Epelboin L, editors. Comparaison de l’évolution de patients traités pour une infection aigue à Coxiella burnetii pas macrolides versus doxycycline en Guyane française entre novembre 2013 et mai 2016. 3ème Journée des travaux scientifiques des jeunes médecins de Guyane; 2019 5 dec 2019; Cayenne, French Guiana.\nMelenotte C, Caputo A, Bechah Y, Lepidi H, Terras J, Kowalczewska M, et al. The hypervirulent Coxiella burnetii Guiana strain compared in silico, in vitro and in vivo to the Nine Mile and the German strain. Clin Microbiol Infect. 2019;25:1155.e1–8.\nD’Elia C, Rozental T, Fernandes J, Alves de Souza TM, Soares Athaide E, Pantoja Marques J, et al. Search of Coxiella burnetii infection in samples of acute febrile cases treated in Amapá, on the border with French Guiana, an endemic country for Q fever. 30th Brazilian Society for Virology 2019 Annual Meeting; Cuiabá, Mato Grosso, Brazil2019.\nEpelboin L, Nacher M, Mahamat A, Pommier de Santi V, Berlioz-Arthaud A, Eldin C, et al. Q Fever in French Guiana: tip of the Iceberg or Epidemiological Exception? PLoS Negl Trop Dis. 2016;10(5):e0004598.\nEcheverria G, Reyna-Bello A, Minda-Aluisa E, Celi-Erazo M, Olmedo L, Garcia HA, et al. Serological evidence of Coxiella burnetii infection in cattle and farm workers: is Q fever an underreported zoonotic disease in Ecuador? Infect Drug Resist. 2019;12:701–6.\nTa TH, Jimenez B, Navarro M, Meije Y, Gonzalez FJ, Lopez-Velez R. Q Fever in returned febrile travelers. J Travel Med. 2008;15(2):126–9.\nLemos ER, Rozental T, Mares-Guia MA, Almeida DN, Moreira N, Silva RG, et al. Q fever as a cause of fever of unknown origin and thrombocytosis: first molecular evidence of Coxiella burnetii in Brazil. Vector Borne Zoonotic Dis. 2011;11(1):85–7.\nMares-Guia MA, Rozental T, Guterres A, Ferreira Mdos S, Botticini Rde G, Terra AK, et al. Molecular identification of Q fever in patients with a suspected diagnosis of dengue in Brazil in 2013-2014. Am J Trop Med Hyg. 2016;94(5):1090–4.\n• von Ranke FM, Clemente Pessoa FM, Afonso FB, Gomes JB, Borghi DP, Alves de Melo AS, et al. Acute Q fever pneumonia: high-resolution computed tomographic findings in six patients. Br J Radiol. 2019;92(1095):20180292 This paper shows the likely major underestimation of Coxiella burnetii in acute fevers in Brazil.\nde Lemos ERS, Rozental T, Siqueira BN, Júnior AAP, Joaquim TE, da Silva RG, et al. Q fever in military firefighters during cadet training in Brazil. Am J Trop Med Hyg. 2018;99(2):303–5.\nLamas CC, Rozental T, Boia MN, Favacho AR, Kirsten AH, da Silva AP, et al. Seroprevalence of Coxiella burnetii antibodies in human immunodeficiency virus-positive patients in Jacarepagua, Rio de Janeiro, Brazil. Clin Microbiol Infect. 2009;15(Suppl 2):140–1.\nRozental T, Silva A, Oliveira RC, Favacho ARM, Oliveira MLA, Bastos FI, et al. Seroprevalence of Bartonella spp., Coxiella burnetii, and Hantavirus among people who inject drugs in Rio de Janeiro, Brazil: a retrospective assessment of a biobank. Rev Inst Med Trop Sao Paulo. 2018;60:e31.\nMares-Guia Monteiro de Mello MA, Rozental T, Guterres A, Gomes R, Almeida DN, Moreira NS, et al. Molecular identification of the agent of Q fever - Coxiella burnetii - in domestic animals in State of Rio de Janeiro. Brazil Rev Soc Bras Med Trop. 2014;47(2):231–4.\nMares-Guia M, Guterres A, Rozental T, Ferreira MDS, Lemos ERS. Clinical and epidemiological use of nested PCR targeting the repetitive element IS1111 associated with the transposase gene from Coxiella burnetii. Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]. 2018;49(1):138–43.\nde Oliveira JMB, Rozental T, de Lemos ERS, Forneas D, Ortega-Mora LM, Porto WJN, et al. Coxiella burnetii in dairy goats with a history of reproductive disorders in Brazil. Acta Trop. 2018;183:19–22.\nFerreira MS, Guterres A, Rozental T, Novaes RLM, Vilar EM, Oliveira RC, et al. Coxiella and Bartonella spp. in bats (Chiroptera) captured in the Brazilian Atlantic Forest biome. BMC Vet Res. 2018;14(1):279.\nRozental T, Ferreira MS, Guterres A, Mares-Guia MA, Teixeira BR, Goncalves J, et al. Zoonotic pathogens in Atlantic Forest wild rodents in Brazil: Bartonella and Coxiella infections. Acta Trop. 2017;168:64–73.\nRozental T, Scafutto de Faria L, Silva MR, Ribeiro JB, Ribeiro Araujo F, Rodrigues da Costa R, et al. Ocorrência de Coxiella burnetii em queijo Minas artesanal de leite cru: resultados preliminares de um preocupante problema de saúde pública. Rev Med Minas Gerais. 2018;28(Supl 5):e-S280510.\nRozental T, Faria LS, Forneas D, Guterres A, Ribeiro JB, Araújo FR, et al. First molecular detection of Coxiella burnetii in Brazilian artisanal cheese: a neglected food safety hazard in ready-to-eat raw-milk product. Braz J Infect Dis. 2020;24(3):208–12.\nKaplan MM, Bertagna P. The geographical distribution of Q fever. Bull World Health Organ. 1955;13(5):829–60.\nDupont HT, Brouqui P, Faugere B, Raoult D. Prevalence of antibodies to Coxiella burnetti, Rickettsia conorii, and Rickettsia typhi in seven African countries. Clin Infect Dis. 1995;21(5):1126–33.\nLacheheb A, Raoult D. Seroprevalence of Q-fever in Algeria. Clin Microbiol Infect. 2009;15(Suppl 2):167–8.\nMediannikov O, Fenollar F, Socolovschi C, Diatta G, Bassene H, Molez JF, et al. Coxiella burnetii in humans and ticks in rural Senegal. 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diseases are a serious concern in Europe since the proliferation of invasive mosquito species increases the risk of epidemics. Aedes spp. (Diptera: Culicidae) are among the most dangerous mosquito vectors in Europe. Among Aedes spp., less attention has been paid to the North American invasive species, Aedes atropalpus and Aedes triseriatus, although these species are vectors of serious diseases. This article aims to provide information about the current status and prospective of these species in Europe. While the presence of Ae. atropalpus in the European continent is still debated, Ae. triseriatus is no longer present in the European continent, but accidental introductions have been recently reported. Nevertheless, the climatic changes and global market increase the possibility of introduction of North American Aedes species in Europe. The present article contains a brief overview of the biology, ecology, and vector competence of these two mosquito vectors, outlining their potential to invade new areas and medical importance. We highlighted some bioecological traits that need to be considered to design surveillance programs tailored for these species. Lastly, research challenges aimed to improve basic knowledge and control programs targeting these species are presented.\n",{"EN":1559},"What Do We Know About the Invasive Mosquitoes Aedes atropalpus and Aedes triseriatus?",{"VOID":1561},"Benelli G, Wilke ABB, Beier JC. Aedes albopictus (Asian Tiger Mosquito). Trends Parasitol. 2020;36:942–3.\nMedlock JM, Hansford KM, Versteirt V, Cull B, Kampen H, Fontenille D, et al. An entomological review of invasive mosquitoes in Europe. Bull Entomol Res. 2015;105:637–63.\nBenelli G, Mehlhorn H. Declining malaria, rising of dengue and Zika virus: insights for mosquito vector control. Parasitol Res. 2016;115:1747–54.\nKamal M, Kenawy MA, Rady MH, Khaled AS, Samy AM. Mapping the global potential distributions of two arboviral vectors Aedes aegypti and Ae. albopictus under changing climate. PLoS One. 2018;13(12):e0210122.\nSamy AM, Elaagip AH, Kenawy MA, Ayres CFJ, Peterson AT, Soliman DE. Climate Change influences on the global potential distribution of the mosquito Culex quinquefasciatus, vector of West Nile Virus and Lymphatic Filariasis. PLoS ONE. 2016;11:e0163863.\ndi Giovanni F, Wilke ABB, Beier JC, Pombi M, Mendoza-Roldan JA, Desneux N, et al. Parasitic strategies of arthropods of medical and veterinary importance. Entomol Gen. 2021;41:511–22.\nAngelini R, Finarelli AC, Angelini P, Po C, Petropulacos K, Macini P, et al. An outbreak of chikungunya fever in the province of Ravenna. Italy Euro Surveill. 2007;12:3260.\nAngelini R, Finarelli AC, Angelini P, Po C, Petropulacos K, Silvi G, et al. Chikungunya in north-eastern Italy: a summing up of the outbreak. Euro Surveill. 2007;12:3313.\nRezza G, Nicoletti L, Angelini R, Romi R, Finarelli A, Panning M, et al. Infection with chikungunya virus in Italy: an outbreak in a temperate region. The Lancet. 2007;370:1840–6.\nGrandadam M, Caro V, Plumet S, Thiberge JM, Souarès Y, Failloux AB, et al. Chikungunya Virus, Southeastern France. Emerg Infect Dis. 2011;17:910.\nla Ruche G, Souarès Y, Armengaud A, Peloux-Petiot F, Delaunay P, Desprès P, et al. First two autochthonous dengue virus infections in metropolitan France, September 2010. Euro Surveill. 2010;15:1–5.\n•• Wilke ABB, Benelli G, Beier JC. Anthropogenic changes and associated impacts on vector-borne diseases. Trends Parasitol. 2021;37:1027–30. Forum article outlining how, when and why anthropogenic habitat modifications can affect vector populations and the spread vector-borne diseases.\nWilke ABB, Chase C, Vasquez C, Carvajal A, Medina J, Petrie WD, et al. Urbanization creates diverse aquatic habitats for immature mosquitoes in urban areas. Sci Rep. 2019;9:1–11.\nBrugueras S, Fernández-Martínez B, Martínez-de la Puente J, Figuerola J, Porro TM, Rius C, et al. Environmental drivers, climate change and emergent diseases transmitted by mosquitoes and their vectors in southern Europe: A systematic review. Environ Res. 2020;191:110038.\nWalter Reed Biosystematics Unit (WRBU), Aedes atropalpus (Coquillett, 1902). 2021;https:\u002F\u002Fwrbu.si.edu\u002Fvectorspecies\u002Fmosquitoes\u002Fatropalpus [access: November, 9 2022].\nEuropean Centre for Disease Prevention and Control (ECDC), Aedes atropalpus - current known distribution: March 2022. 2022; https:\u002F\u002Fwww.ecdc.europa.eu\u002Fen\u002Fpublications-data\u002Faedes-atropalpus-current-known-distribution-march-2022 [access: November, 9 2022].\nKampen H, Medlock JM, Vaux AGC, Koenraadt CJM, van Vliet AJH, Bartumeus F, et al. Approaches to passive mosquito surveillance in the EU. Parasit Vectors. 2015;8:1–13.\nKoban MB, Kampen H, Scheuch DE, Frueh L, Kuhlisch C, Janssen N, et al. The Asian bush mosquito Aedes japonicus japonicus (Diptera: Culicidae) in Europe, 17 years after its first detection, with a focus on monitoring methods. Parasit Vectors. 2019;12:1–13.\n•• Freier JE, Beier JC. Oral and transovarial transmission of La Crosse virus by Aedes atropalpus. Am J Trop Med Hyg. 1984;33:708–14. The study provides clear evidence of the transmission dynamics of La Cross virus in its mosquito vector Aedes atropalpus.\nScholte EJ, den Hartog W, Braks M, Reusken C, Dik M, Hessels A. First report of a North American invasive mosquito species Ochlerotatus atropalpus (Coquillett) in the Netherlands, 2009. Euro Surveill. 2009;14:19400.\nTurell MJ, Dohm DJ, Sardelis MR, O’Guinn ML, Andreadis TG, Blow JA. An update on the potential of North American mosquitoes (Diptera: Culicidae) to transmit West Nile Virus. J Med Entomol. 2005;42:57–62.\nJuliano SA, Philip LL. Ecology of invasive mosquitoes: effects on resident species and on human health. Ecol Lett. 2005;8:558–74.\nCebrián-Camisón S, de la Puente JM, Figuerola J. A literature review of host feeding patterns of invasive Aedes mosquitoes in Europe. Insects. 2020;11:848.\n• Romi R, Sabatinelli G, Savelli LG, Raris M, Zago M, Malatesta R. Identification of a North American mosquito species, Aedes atropalpus (Diptera: Culicidae), in Italy. J Am Mosq Control Assoc. 1997;13:245–6. Aedes atropalpus firstly reported in Italy.\nRomi R, di Luca M, Majori G. Current status of Aedes albopictus and Aedes atropalpus in Italy. J Am Mosq Control Assoc. 1999;15:425–7.\nAndreadis TG, Wolfe RJ. Evidence for reduction of native mosquitoes with increased expansion of invasive Ochlerotatus japonicus japonicus (Diptera: Culicidae) in the Northeastern United States. J Med Entomol. 2010;47:43–52.\nArmistead JS, Nishimura N, Escher RL, Lounibos LP. Larval competition between Aedes japonicus and Aedes atropalpus (Diptera: Culicidae) in simulated rock pools. J Vector Ecol. 2008;33:238–46.\nYee DA. Tires as habitats for mosquitoes: A review of studies within the Eastern United States. J Med Entomol. 2008;45:581–93.\nBorucki MK, Kempf BJ, Blitvich BJ, Blair CD, Beaty BJ. La Crosse virus: replication in vertebrate and invertebrate hosts. Microbes Infect. 2002;4:341–50.\nMedlock JM, Hansford KM, Schaffner F, Versteirt V, Hendrickx G, Zeller H, et al. A review of the invasive mosquitoes in Europe: Ecology, public health risks, and control options. Vector Borne Zoonotic Dis. 2012;12:435–47.\n•• Freier JE, Grimstad PR. Transmission of dengue virus by orally infected Aedes triseriatus. Am J Trop Med Hyg. 1983;32:1429–34. The study provides evidence of the transmission dynamics of dengue virus in its mosquito vector Aedes triseriatus.\nMcJunkin JE, De los Reyes EC, Irazuzta JE, Caceres MJ, Khan TR, Minnich LL, et al. La Crosse encephalitis in children. New England J Med. 2001;344(11):801–7.\nAliota MT, Peinado SA, Osorio JE, Bartholomay LC. Culex pipiens and Aedes triseriatus mosquito susceptibility to Zika Virus. Emerg Infect Dis. 2016;22:1857.\nAndreadis TG, Anderson JF, Armstrong PM, Main AJ. Isolations of Jamestown Canyon virus (Bunyaviridae: Orthobunyavirus) from field-collected mosquitoes (Diptera: Culicidae) in Connecticut, USA: a ten-year analysis, 1997–2006. Vector Borne Zoonotic Dis. 2008;8:175–89.\nDavis MH, Hogge AL, Corristan EC, Ferrell JF. Mosquito transmission of Venezuelan Equine Encephalomyelitis Virus from experimentally infected dogs. Am J Trop Med Hyg. 1966;15:227–30.\nStyer LM, Kent KA, Albright RG, Bennett CJ, Kramer LD, Bernard KA. Mosquitoes inoculate high doses of West Nile Virus as they probe and feed on live hosts. PLoS ONE. 2007;3:e132.\nKhatchikian CE, Dennehy JJ, Vitek CJ, Livdahl T. Climate and geographic trends in hatch delay of the treehole mosquito, Aedes triseriatus Say (Diptera: Culicidae). J Vector Ecol. 2009;34:119–28.\nAlto BW. Interspecific larval competition between invasive Aedes japonicus and native Aedes triseriatus (Diptera: Culicidae) and adult longevity. J Med Entomol. 2011;48:232–42.\nSchaffner F, Medlock JM, van Bortel W. Public health significance of invasive mosquitoes in Europe. Clin Microbiol Infect Elsevier. 2013;19:685–92.\nGonzález MI, Encarnação J, Aranda C, Osório H, Montalvo T, Talavera S. The use of artificial intelligence and automatic remote monitoring for mosquito surveillance. Ecol Control Vector Borne Dis. 2022;7:211–23.\nJohnson BJ, Manby R, Devine GJ. The use of automated traps to assess the efficacy of insecticide barrier treatments against abundant mosquitoes in remote environments. J Med Entomol. 2022;59:384–9.\nHardy JL, Rosen L, Reeves WC, Scrivani RP, Presser SB. Experimental transovarial transmission of St. Louis encephalitis virus by Culex and Aedes mosquitoes. Am J Trop Med Hyg. 1984;33:166–75.\nGiunti G, Becker N, Benelli G. Invasive mosquito vectors in Europe: from bioecology to surveillance and management. Acta Trop. 2023;239:106832. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.actatropica.2023.106832.",{"VOID":1563},"10.1007\u002Fs40475-023-00284-x","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs40475-023-00284-x",[1566,1581,1596,1611],{"id":1567,"sortIndex":32,"researcher":28,"roles":1568,"affiliations":1569,"properties":1578,"displayName":1580,"givenName":28,"familyName":28},"429203ed-d8e2-4019-86ce-69d913ed7e26",[968],[1570],{"id":1571,"sortIndex":32,"affiliation":1572,"properties":28},"0daf45db-1bb9-4393-97b6-46893d2950a8",{"id":1571,"createTime":28,"updateTime":28,"relativeEntities":1573,"slug":28,"properties":1574,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1577,"statistic":28},[],{"title":1575},{"VI":1576},"Department of Pharmacy, University of Salerno, Fisciano, Italy",[],{"title":1579},{"VI":1580},"Giulia Giunti",{"id":1582,"sortIndex":40,"researcher":28,"roles":1583,"affiliations":1584,"properties":1593,"displayName":1595,"givenName":28,"familyName":28},"bf85dabc-fe74-4606-b7e6-3453a9b79a11",[968],[1585],{"id":1586,"sortIndex":32,"affiliation":1587,"properties":28},"c93cdf9d-743c-4144-9df8-c689a3506e02",{"id":1586,"createTime":28,"updateTime":28,"relativeEntities":1588,"slug":28,"properties":1589,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1592,"statistic":28},[],{"title":1590},{"VI":1591},"Laboratory for Computational Epidemiology and Public Health, Department of Epidemiology and Biostatistics, Indiana University School of Public Health, Bloomington, USA",[],{"title":1594},{"VI":1595},"André B. B. Wilke",{"id":1597,"sortIndex":123,"researcher":28,"roles":1598,"affiliations":1599,"properties":1608,"displayName":1610,"givenName":28,"familyName":28},"c0c7452f-3ce2-44eb-9fda-528e75d4499d",[968],[1600],{"id":1601,"sortIndex":32,"affiliation":1602,"properties":28},"5c4bf576-0769-4508-9e32-1b0750786225",{"id":1601,"createTime":28,"updateTime":28,"relativeEntities":1603,"slug":28,"properties":1604,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1607,"statistic":28},[],{"title":1605},{"VI":1606},"Division of Environmental Health Sciences, Department of Public Health Sciences, Miller School of Medicine, University of Miami, Miami, USA",[],{"title":1609},{"VI":1610},"John C. Beier",{"id":1612,"sortIndex":42,"researcher":28,"roles":1613,"affiliations":1614,"properties":1623,"displayName":1625,"givenName":28,"familyName":28},"ffe1a9c5-f721-4bf5-892d-183e9b0d99cc",[968],[1615],{"id":1616,"sortIndex":32,"affiliation":1617,"properties":28},"b3c4dee8-30b2-4be3-883c-bd9fc9497126",{"id":1616,"createTime":28,"updateTime":28,"relativeEntities":1618,"slug":28,"properties":1619,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1622,"statistic":28},[],{"title":1620},{"VI":1621},"Department of Agriculture, Food, and Environment, University of Pisa, Pisa, Italy",[],{"title":1624},{"VI":1625},"Giovanni Benelli",{"url":1564,"publisher":1627,"properties":1672},{"id":868,"createTime":869,"updateTime":870,"relativeEntities":1628,"slug":872,"properties":1629,"entityType":25,"verifyStatus":880,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":32,"subjectFields":1632,"manageAffiliations":1641,"indexDatabases":1652,"url":28,"thumbnailPath":28,"statistic":1667,"gsStatistic":28,"type":55,"analyzePriority":28},[],{"issn":1630,"title":1631},{"VOID":875},{"EN":877},[1633,1637],{"id":883,"createTime":28,"updateTime":28,"relativeEntities":1634,"label":1635,"description":1636,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":886},{},{"id":889,"createTime":28,"updateTime":28,"relativeEntities":1638,"label":1639,"description":1640,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":892},{},[1642,1647],{"id":896,"createTime":28,"updateTime":28,"relativeEntities":1643,"slug":28,"properties":1644,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1646,"statistic":28},[],{"title":1645},{"EN":900},[902],{"id":904,"createTime":28,"updateTime":28,"relativeEntities":1648,"slug":28,"properties":1649,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1651,"statistic":28},[],{"title":1650},{"EN":908},[],[1653,1660],{"id":912,"indexDatabase":1654,"url":918,"indexYears":28,"academicFieldIds":1659,"indexDatabaseRanking":28},{"id":803,"createTime":28,"updateTime":28,"relativeEntities":1655,"label":1656,"description":1657,"key":810,"publicationTags":1658,"standard":28},[],{"EN":806,"VI":806},{"EN":808,"VI":809},[812,813],[920,921,922],{"id":924,"indexDatabase":1661,"url":930,"indexYears":931,"academicFieldIds":1666,"indexDatabaseRanking":935},{"id":775,"createTime":28,"updateTime":28,"relativeEntities":1662,"label":1663,"description":1664,"key":781,"publicationTags":1665,"standard":28},[],{"EN":778,"VI":778},{"EN":778,"VI":780},[783],[933,934],{"impactFactor":32,"impactFactorByYear":1668,"i10Index":32,"i10IndexLast5Year":32,"totalPublication":218,"totalPublicationByYear":1669,"totalCitation":32,"totalCitationByYear":1670,"totalCitationPerPublication":32,"totalCitationPerPublicationByYear":1671,"hindexLast5Year":32,"hindex":32},{},{"2013":42,"2014":146,"2015":205,"2016":199,"2017":130,"2018":128,"2019":126,"2020":145,"2021":128,"2022":127,"2023":127,"2024":40},{},{},{"pages":1673,"volume":1675},{"VOID":1674},"41-46",{"VOID":1676},"10","2023-02-04",2023,[935,812],{"id":1681,"createTime":1682,"updateTime":1683,"relativeEntities":1684,"slug":1685,"properties":1686,"entityType":960,"verifyStatus":26,"verifyTime":1683,"verifyNote":962,"languages":28,"translateLanguages":28,"viewCount":32,"primaryUrl":1695,"fullTextUrl":28,"authors":1696,"publicationType":1083,"publisherRelationship":1734,"citationCount":28,"citationInfo":28,"publishDate":1785,"publishYear":1786,"citationAnalyzeStatus":880,"lastCitationAnalyze":28,"indexDatabases":1787,"openAccess":28,"references":28,"isForceReanalyzing":1138},"08f567c6-8357-4635-ac39-efe8b5f35ddc","2024-02-07T10:52:35.128+00:00","2025-02-12T03:04:42.764+00:00",[],"The-Role-of-Maternal-Breast-Milk-in-Preventing-Infantile-Diarrhea-in-the-Developing-World",{"abstract":1687,"title":1689,"references":1691,"doi":1693},{"EN":1688},"Multiple interventions have been designed to decrease mortality and disability in children. Among these, breastfeeding is the most cost-effective intervention for protecting children against diarrhea and all causes of mortality. Human milk is uniquely suited to the human infant, both in its nutritional composition and in the nonnutritive bioactive factors that promote survival and healthy development. Suboptimal breastfeeding has been linked with numerous adverse child health outcomes including increased incidence of diarrhea and pneumonia. This review provides an update regarding recent studies on the effect of breastfeeding on diarrhea morbidity and mortality in children in developing countries, describes major human milk components responsible for this protective effect (oligosaccharides, secretory immunoglobulins, lactoferrin, bacterial microbiota, etc.), and highlights areas for future research in this topic. Breastfeeding promotion remains an intervention of enormous public health potential to decrease global mortality and promote better growth and neurodevelopment in children.",{"EN":1690},"The Role of Maternal Breast Milk in Preventing Infantile Diarrhea in the Developing World",{"VOID":1692},"Liu L, Johnson HL, Cousens S, et al. Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. Lancet. 2012;379:2151–61. The Child Health Epidemiology Reference Group (CHERG) of WHO and UNICEF has systematically estimated the distribution of child mortality by cause at the regional and global level for year 2010. Neonatal complications, pneumonia and diarrhea are the leading causes of death worldwide.\nBhutta ZA, Black RE. Global maternal, newborn, and child health–so near and yet so far. N Engl J Med. 2013;369:2226–35.\nGuerrant RL, Oriá RB, Moore SR, et al. Malnutrition as an enteric infectious disease with long-term effects on child development. Nutr Rev. 2008;66:487–505.\nWalker CLF, Friberg IK, Binkin N, et al. Scaling up diarrhea prevention and treatment interventions: a lives saved tool analysis. PLoS Med. 2011;8:e1000428.\nBhutta ZA, Das JK, Walker N, et al. Interventions to address deaths from childhood pneumonia and diarrhoea equitably: what works and at what cost? Lancet. 2013;381:1417–29. Systematic review of studies showing the effectiveness of various interventions (preventive and therapeutic) against childhood diarrhea and pneumonia, and relevant delivery strategies. Breastfeeding is one of the most cost-effective interventions to lessen diarrhea burden.\nJones G, Steketee RW, Black RE, et al. How many child deaths can we prevent this year? Lancet. 2003;362:65–71.\nMorrow AL, Rangel JM. Human milk protection against infectious diarrhea: implications for prevention and clinical care. Semin Pediatr Infect Dis. 2004;15:221–8.\nLamberti LM, Fischer Walker CL, Noiman A, et al. Breastfeeding and the risk for diarrhea morbidity and mortality. BMC Public Health. 2011;11:S15. A systematic review of 18 clinical studies found a significant positive effect of breastfeeding against diarrhea incidence, prevalence, hospitalization and mortality. The degree of protection is depended on the level of breastfeeding exposure. This supports current WHO recommendation for exclusive breastfeeding during the first 6 months of life as a key child survival intervention.\nArifeen S, Black RE, Antelman G, et al. Exclusive breastfeeding reduces acute respiratory infection and diarrhea deaths among infants in Dhaka slums. Pediatrics. 2001;108:E67.\nLim SS, Vos T, Flaxman AD, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380:2224–60. This study evaluated the leading risk factors that increase mortality and disability worldwide. Suboptimal breastfeeding showed a significant negative effect on children health, which was measure by deaths and disability-adjusted life years.\nBlack RE, Victora CG, Walker SP, et al. Maternal and child undernutrition and overweight in low-income and middle-income countries. Lancet. 2013;382:427–51. Systematic evaluation of the nutritional status and factors associated with undernutrition of mothers and children from low and middle income countries. Suboptimal breastfeeding increased the risk of death in children younger than 2 years of age.\nRoberts TJ, Carnahan E, Gakidou E. Can breastfeeding promote child health equity? A comprehensive analysis of breastfeeding patterns across the developing world and what we can learn from them. BMC Med. 2013;11:254. Analysis of breastfeeding practices in 137 developing countries from 1990 to 2010. Researchers found a wide range of breastfeeding prevalence and an increase in disability-adjusted life years secondary to suboptimal breastfeeding.\nWorld Health Organization. The optimal duration of exclusive breastfeeding: report of an expert consultation. Geneva: World Health Organization; 2001.\nSection on Breastfeeding. Breastfeeding and the use of human milk. Pediatrics 2012, 129:e827-841.\nHaroon S, Das JK, Salam RA, et al. Breastfeeding promotion interventions and breastfeeding practices: a systematic review. BMC Public Health. 2013;13:1–18. Systematic review of 110 randomized studies on the effectiveness of various intervention and delivery strategies to increase rates of exclusive breastfeeding.\nImdad A, Yakoob MY, Bhutta ZA. Effect of breastfeeding promotion interventions on breastfeeding rates, with special focus on developing countries. BMC Public Health. 2011;11:S24.\nLawrence RM. Circumstances when breastfeeding is contraindicated. Pediatr Clin North Am. 2013;60:295–318.\nBosch AM, Grootenhuis MA, Bakker HD, et al. Living with classical galactosemia: health-related quality of life consequences. Pediatrics. 2004;113:e423–8.\nHorvath T, Madi BC, Iuppa IM, et al. Interventions for preventing late postnatal mother-to-child transmission of HIV. Cochrane Database Syst Rev. 2009;1, CD006734.\nGonçalves DU, Proietti FA, Ribas JGR, et al. Epidemiology, treatment, and prevention of human T-cell leukemia virus type 1-associated diseases. Clin Microbiol Rev. 2010;23:577–89.\nBallard O, Morrow AL. Human Milk Composition. Pediatr Clin North Am. 2013;60:49–74. Very comprehensive review of the nutrients and bioactive factors present in human milk; the factors associated with the variability on human milk composition, and the impact of storage and pasteurization on milk components.\nSmilowitz JT, O’Sullivan A, Barile D, et al. The human milk metabolome reveals diverse oligosaccharide profiles. J Nutr. 2013;143:1709–18.\nBode L. Human milk oligosaccharides: every baby needs a sugar mama. Glycobiology. 2012;22:1147–462. Comprehensive review on human milk oligosaccharides structure, composition, variation, biosynthesis, and postulated beneficial effects for the breastfed neonate: antiadhesive antimicrobial, immune modulation, NEC protection, brain development among others.\nMorrow AL, Ruiz-Palacios GM, Jiang X, et al. Human-milk glycans that inhibit pathogen binding protect breast-feeding infants against infectious diarrhea. J Nutr. 2005;135:1304–7.\nNewburg DS, Ruiz-Palacios GM, Morrow AL. Human milk glycans protect infants against enteric pathogens. Annu Rev Nutr. 2005;25:37–58.\nZivkovic AM, German JB, Lebrilla CB, et al. Human milk glycobiome and its impact on the infant gastrointestinal microbiota. Proc Natl Acad Sci. 2011;108:4653–8.\nRuiz-Palacios GM, Cervantes LE, Ramos P, et al. Campylobacter jejuni binds intestinal H(O) antigen (Fuc alpha 1, 2Gal beta 1, 4GlcNAc), and fucosyloligosaccharides of human milk inhibit its binding and infection. J Biol Chem. 2003;278:14112–20.\nMorrow AL, Ruiz-Palacios GM, Altaye M, et al. Human milk oligosaccharides are associated with protection against diarrhea in breast-fed infants. J Pediatr. 2004;145:297–303.\nCoppa GV, Zampini L, Galeazzi T, et al. Human milk oligosaccharides inhibit the adhesion to Caco-2 cells of diarrheal pathogens: Escherichia coli, Vibrio cholerae, and Salmonella fyris. Pediatr Res. 2006;59:377–82.\nCano-Mancera R, López-Revilla R. Inhibition of the adhesion of Entamoeba histolytica trophozoites to human erythrocytes by carbohydrates. Parasitol Res. 1987;74:18–22.\nBrandtzaeg P. The mucosal immune system and its integration with the mammary glands. J Pediatr. 2010;156:S8–15.\nPeterson R, Cheah WY, Grinyer J, et al. Glycoconjugates in human milk: Protecting infants from disease. Glycobiology. 2013;23:1425–38. Comprehensive review of the variety of human milk glycoconjugates, their function and the mechanism for preventing children’s diseases.\nDurand D, Ochoa TJ, Bellomo SME, et al. Detection of secretory immunoglobulin A in human colostrum as mucosal immune response against proteins of the type III secretion system of Salmonella, Shigella and enteropathogenic Escherichia coli. Pediatr Infect Dis J. 2013;32:1122–6.\nKorpe PS, Liu Y, Siddique A, et al. Breast milk parasite-specific antibodies and protection from amebiasis and cryptosporidiosis in Bangladeshi infants: a prospective cohort study. Clin Infect Dis. 2013;56:988–92.\nBerlutti F, Pantanella F, Natalizi T, et al. Antiviral properties of lactoferrin–a natural immunity molecule. Mol Basel Switz. 2011;16:6992–7018.\nVogel HJ. Lactoferrin, a bird’s eye view. Biochem Cell Biol. 2012;90:233–44. Review of lactoferrin structure and beneficial functional properties: antimicrobial, anti-cancer, immunoregulatory, and other effects on human health.\nBrock JH. Lactoferrin–50 years on. Biochem Cell Biol. 2012;90:245–51.\nBaker HM, Baker EN. A structural perspective on lactoferrin function. Biochem Cell Biol. 2012;90:320–8.\nOchoa TJ, Cleary TG. Effect of lactoferrin on enteric pathogens. Biochimie. 2009;91:30–4.\nGomez HF, Ochoa TJ, Herrera-Insua I, et al. Lactoferrin protects rabbits from Shigella flexneri-induced inflammatory enteritis. Infect Immun. 2002;70:7050–3.\nMosquito S, Ochoa TJ, Cok J, et al. Effect of bovine lactoferrin in Salmonella ser. Typhimurium infection in mice. Biometals. 2010;23:515–21.\nRivera FP, Medina AM, Bezada S, et al. Bovine lactoferrin decreases cholera-toxin-induced intestinal fluid accumulation in mice by ganglioside interaction. PloS One. 2013;8:e59253.\nLingappan K, Arunachalam A, Pammi M. Lactoferrin and the newborn: current perspectives. Expert Rev Anti Infect Ther. 2013;11:695–707.\nOchoa TJ, Pezo A, Cruz K, et al. Clinical studies of lactoferrin in children. Biochem Cell Biol. 2012;90:457–67. Review of 19 clinical studies evaluating the effect human or bovine lactoferrin on various health outcomes in children. Three studies focused on prevention and treatment of enteric infections and possible mechanisms of protection.\nEgashira M, Takayanagi T, Moriuchi M, et al. Does daily intake of bovine lactoferrin-containing products ameliorate rotaviral gastroenteritis? Acta Paediatr. 2007;96:1242–4.\nZavaleta N, Figueroa D, Rivera J, et al. Efficacy of rice-based oral rehydration solution containing recombinant human lactoferrin and lysozyme in Peruvian children with acute diarrhea. J Pediatr Gastroenterol Nutr. 2007;44:258–64.\nOchoa TJ, Chea-Woo E, Campos M, et al. Impact of lactoferrin supplementation on growth and prevalence of Giardia colonization in children. Clin Infect Dis. 2008;46:1881–3.\nOchoa TJ, Chea-Woo E, Baiocchi N, et al. Randomized double-blind controlled trial of bovine lactoferrin for prevention of diarrhea in children. J Pediatr. 2013;162:349–56. Randomized trial of bovine lactoferrin supplementation in children with intense diarrhea surveillance. There was no effect on diarrhea incidence; however, there was a significant decrease in diarrhea longitudinal prevalence and severity, although not clinically significant at the dose studied.\nHill DR, Rho HK, Kessler SP, et al. Human milk hyaluronan enhances innate defense of the intestinal epithelium. J Biol Chem. 2013;288(40):29090–104.\nLiu B, Yu Z, Chen C, et al. Human milk mucin 1 and mucin 4 inhibit Salmonella enterica serovar Typhimurium invasion of human intestinal epithelial cells in vitro. J Nutr. 2012;142:1504–9.\nNewburg DS, Peterson JA, Ruiz-Palacios GM, et al. Role of human-milk lactadherin in protection against symptomatic rotavirus infection. Lancet. 1998;351:1160–4.\nAsensi MT, Martínez-Costa C, Buesa J. Anti-rotavirus antibodies in human milk: quantification and neutralizing activity. J Pediatr Gastroenterol Nutr. 2006;42:560–7.\nFernandez L, Langa S, Martin V, Maldonado A, Jimenez E, Martin R, et al. The human milk microbiota: origin and potential roles in health and disease. Pharmacol Res Off J Ital Pharmacol Soc. 2013;69:1–10.\nLatuga MS, Stuebe A, Seed PC. A review of the source and function of microbiota in breast milk. Semin Reprod Med. 2014;32:68–73.\nHunt KM, Foster JA, Forney LJ, et al. Characterization of the Diversity and Temporal Stability of Bacterial Communities in Human Milk. PLoS One. 2011;6:e21313.\nMartín R, Heilig GHJ, Zoetendal EG, et al. Diversity of the Lactobacillus group in breast milk and vagina of healthy women and potential role in the colonization of the infant gut. J Appl Microbiol. 2007;103:2638–44.\nMartin R, Jimenez E, Heilig H, et al. Isolation of Bifidobacteria from Breast Milk and Assessment of the Bifidobacterial Population by PCR-Denaturing Gradient Gel Electrophoresis and Quantitative Real-Time PCR. Appl Environ Microbiol. 2009;75:965–9.\nKawano A, Emori Y. Changes in maternal secretory immunoglobulin a levels in human milk during 12 weeks after parturition. Am J Hum Biol. 2013;25:399–403.\nGabrielli O, Zampini L, Galeazzi T, et al. Preterm milk oligosaccharides during the first month of lactation. Pediatrics. 2011;128:e1520–31.\nCabrera-Rubio R, Collado MC, Laitinen K, et al. The human milk microbiome changes over lactation and is shaped by maternal weight and mode of delivery. Am J Clin Nutr. 2012;96:544–51.\nWorld Health Organization. Global strategy on infant and young child feeding. Geneva: World Health Organization; 2003.",{"VOID":1694},"10.1007\u002Fs40475-014-0015-x","http:\u002F\u002Flink.springer.com\u002F10.1007\u002Fs40475-014-0015-x",[1697,1712],{"id":1698,"sortIndex":32,"researcher":28,"roles":1699,"affiliations":1700,"properties":1709,"displayName":1711,"givenName":28,"familyName":28},"b7b6529c-f2dd-47ef-86f6-865ac69303f3",[968],[1701],{"id":1702,"sortIndex":32,"affiliation":1703,"properties":28},"36ec6edd-33d2-4af5-95e0-3c66fa0a1c84",{"id":1702,"createTime":28,"updateTime":28,"relativeEntities":1704,"slug":28,"properties":1705,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1708,"statistic":28},[],{"title":1706},{"VI":1707},"Department of Pediatrics, Instituto de Medicina Tropical “Alexander von Humboldt”, Universidad Peruana Cayetano Heredia, Lima, Peru",[],{"title":1710},{"VI":1711},"Christie G. Turin",{"id":1713,"sortIndex":40,"researcher":28,"roles":1714,"affiliations":1715,"properties":1731,"displayName":1733,"givenName":28,"familyName":28},"376219df-8fac-4cd2-a2e8-1e99df5c20ee",[968],[1716,1722],{"id":1702,"sortIndex":32,"affiliation":1717,"properties":28},{"id":1702,"createTime":28,"updateTime":28,"relativeEntities":1718,"slug":28,"properties":1719,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1721,"statistic":28},[],{"title":1720},{"VI":1707},[],{"id":1723,"sortIndex":40,"affiliation":1724,"properties":1730},"4e916d58-271b-4795-9119-9703d1323a15",{"id":1723,"createTime":28,"updateTime":28,"relativeEntities":1725,"slug":28,"properties":1726,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1729,"statistic":28},[],{"title":1727},{"VI":1728},"Center for Infectious Diseases, University of Texas School of Public Health, Houston, USA",[],{},{"title":1732},{"VI":1733},"Theresa J. Ochoa",{"url":1695,"publisher":1735,"properties":1780},{"id":868,"createTime":869,"updateTime":870,"relativeEntities":1736,"slug":872,"properties":1737,"entityType":25,"verifyStatus":880,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":32,"subjectFields":1740,"manageAffiliations":1749,"indexDatabases":1760,"url":28,"thumbnailPath":28,"statistic":1775,"gsStatistic":28,"type":55,"analyzePriority":28},[],{"issn":1738,"title":1739},{"VOID":875},{"EN":877},[1741,1745],{"id":883,"createTime":28,"updateTime":28,"relativeEntities":1742,"label":1743,"description":1744,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":886},{},{"id":889,"createTime":28,"updateTime":28,"relativeEntities":1746,"label":1747,"description":1748,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":892},{},[1750,1755],{"id":896,"createTime":28,"updateTime":28,"relativeEntities":1751,"slug":28,"properties":1752,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1754,"statistic":28},[],{"title":1753},{"EN":900},[902],{"id":904,"createTime":28,"updateTime":28,"relativeEntities":1756,"slug":28,"properties":1757,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1759,"statistic":28},[],{"title":1758},{"EN":908},[],[1761,1768],{"id":912,"indexDatabase":1762,"url":918,"indexYears":28,"academicFieldIds":1767,"indexDatabaseRanking":28},{"id":803,"createTime":28,"updateTime":28,"relativeEntities":1763,"label":1764,"description":1765,"key":810,"publicationTags":1766,"standard":28},[],{"EN":806,"VI":806},{"EN":808,"VI":809},[812,813],[920,921,922],{"id":924,"indexDatabase":1769,"url":930,"indexYears":931,"academicFieldIds":1774,"indexDatabaseRanking":935},{"id":775,"createTime":28,"updateTime":28,"relativeEntities":1770,"label":1771,"description":1772,"key":781,"publicationTags":1773,"standard":28},[],{"EN":778,"VI":778},{"EN":778,"VI":780},[783],[933,934],{"impactFactor":32,"impactFactorByYear":1776,"i10Index":32,"i10IndexLast5Year":32,"totalPublication":218,"totalPublicationByYear":1777,"totalCitation":32,"totalCitationByYear":1778,"totalCitationPerPublication":32,"totalCitationPerPublicationByYear":1779,"hindexLast5Year":32,"hindex":32},{},{"2013":42,"2014":146,"2015":205,"2016":199,"2017":130,"2018":128,"2019":126,"2020":145,"2021":128,"2022":127,"2023":127,"2024":40},{},{},{"pages":1781,"volume":1783},{"VOID":1782},"97-105",{"VOID":1784},"1","2014-03-15",2014,[935,812],{"id":1789,"createTime":1790,"updateTime":1791,"relativeEntities":1792,"slug":1793,"properties":1794,"entityType":960,"verifyStatus":26,"verifyTime":1807,"verifyNote":962,"languages":28,"translateLanguages":1808,"viewCount":32,"primaryUrl":1809,"fullTextUrl":28,"authors":1810,"publicationType":1083,"publisherRelationship":1888,"citationCount":28,"citationInfo":28,"publishDate":1938,"publishYear":1678,"citationAnalyzeStatus":880,"lastCitationAnalyze":28,"indexDatabases":1939,"openAccess":28,"references":28,"isForceReanalyzing":1138},"0a28bbdf-7939-456f-9ec2-6f1d35524a4f","2023-12-26T23:42:06.289+00:00","2025-01-31T04:39:54.745+00:00",[],"Tuberculosis-in-the-European-Region",{"abstract":1795,"title":1798,"keywords":1801,"references":1803,"doi":1805},{"VI":1796,"EN":1797},"Bệnh lao (TB) vẫn là một vấn đề sức khỏe công cộng lớn trên toàn thế giới. Đại dịch COVID-19 và dòng di cư do các điều kiện kinh tế xã hội, biến đổi khí hậu và các vấn đề địa chính trị, chẳng hạn như chiến tranh, là những yếu tố quan trọng ảnh hưởng đến dịch tễ học của bệnh lao ở Châu Âu. Bài viết này nhằm mục đích tổng hợp dữ liệu về bệnh lao trong khu vực này và những phát hiện mới về chiến lược điều trị và phòng ngừa. Trong đại dịch COVID-19, việc tiếp cận các cơ sở y tế và duy trì chăm sóc cho bệnh nhân lao gặp khó khăn, gây hậu quả đến việc chẩn đoán và tỷ lệ mắc bệnh lao. Cuộc xung đột đang diễn ra ở Châu Âu, tại các khu vực có tỷ lệ mắc lao và lao kháng thuốc cao, đã làm giảm khả năng tiếp cận các dịch vụ y tế và sự sẵn có của thuốc chống lao, đồng thời gia tăng di cư của người tị nạn. Dữ liệu mới về các phác đồ điều trị ngắn có thể thay đổi thời gian điều trị và các sự kiện bất lợi. Các chương trình kiểm soát bệnh lao đang đối mặt với những thách thức mới có thể làm thay đổi tỷ lệ mắc lao trong tương lai gần. Các chiến lược kháng sinh mới và các chính sách phòng ngừa được cải thiện có thể cung cấp cơ hội mới để giảm tác động của bệnh lao lên sức khỏe cộng đồng.","Tuberculosis (TB) remains a major public health concern worldwide. The COVID-19 pandemic and migration flow due to socioeconomic conditions, climate change, and geopolitical issues, such as the war, are important drivers influencing TB epidemiology in Europe. This article aims to review the data about TB in this area and the new findings about treatment and prevention strategies. During the COVID-19 pandemic, access to health facilities and retention in care were difficult for TB patients, with consequences on TB diagnosis and TB incidence. The ongoing conflict in Europe, in areas with high prevalence of TB and MDR-TB, has reduced the access to health services and the availability of anti-TB drugs and increased the migration of refugees. New data on short treatment regimens could change the length of therapy and adverse events. TB control programs are facing emerging challenges that could change TB incidence in the near future. Novel antibiotic strategies and improved preventive policies could offer new opportunities to reduce the TB impact on public health.",{"EN":1799,"VI":1800},"Tuberculosis in the European Region","Bệnh Lao ở Khu Vực Châu Âu",{"VI":1802},"bệnh lao, dịch tễ học, COVID-19, di cư, kháng thuốc",{"VOID":1804},"Global tuberculosis report 2022. Geneva: World Health Organization; 2022. Licence: CC BY-NC-SA 3.0 IGO.\nGlobal tuberculosis report 2021. Geneva: World Health Organization; 2021. Licence: CC BY-NC-SA 3.0 IGO.\nGlobal tuberculosis report 2020. Geneva: World Health Organization; 2020. Licence: CC BY-NC-SA 3.0 IGO.\nWorld Health Organization, Impact of the COVID-19 pandemic on TB detection and mortality in 2020. [Online]. Available: https:\u002F\u002Fwww.who.int\u002Fpublications\u002Fm\u002Fitem\u002Fimpact-of-the-covid-19-pandemic-on-tb-detection-and-mortality-in-2020\nPai M, Kasaeva T, Swaminathan S. Covid-19’s devastating effect on tuberculosis care - a path to recovery. N Engl J Med. 2022;386(16):1490–3. https:\u002F\u002Fdoi.org\u002F10.1056\u002FNEJMp2118145.\nNikolayevskyy V, Holicka Y, van Soolingen D, et al. Impact of the COVID-19 pandemic on tuberculosis laboratory services in Europe. Eur Respir J. 2021;57:2003890. https:\u002F\u002Fdoi.org\u002F10.1183\u002F13993003.03890-2020.\nEuropean Centre for Disease Prevention and Control, “Tuberculosis surveillance and monitoring in Europe,” 2021.\nEuropean Centre for Disease Prevention and Control, “Tuberculosis surveillance and monitoring in Europe 2022 –2020 data” 2022\nTogun T, Kampmann B, Stoker NG, Lipman M. Anticipating the impact of the COVID-19 pandemic on TB patients and TB control programmes. Ann Clin Microbiol Antimicrob. 2020;19(1):21.\n• Sotgiu G, Solovic I, Zenner D, Tiberi S, Manika K, Celan C, Chorostowska-Wynimko J, Zumla A, Migliori GB. The war in Ukraine and potential consequences for the TB epidemic in Europe. Int J Tuberc Lung Dis. 2022;26(5):470–1. https:\u002F\u002Fdoi.org\u002F10.5588\u002Fijtld.22.0162. The authors speculate about the consequence of war on TB epidemiology.\n• Holt E. Tuberculosis services disrupted by war in Ukraine. Lancet Infect Dis. 2022;22(5):e129. https:\u002F\u002Fdoi.org\u002F10.1016\u002FS1473-3099(22)00214-6. Holt describes the war impact on TB and focuses about the destruction of health services.\nRoberts L. Surge of HIV, tuberculosis and COVID feared amid war in Ukraine. Nature. 2022;603(7902):557–8.\nEuropean Centre for Disease Prevention and Control and WHO Regional Office for Europe. Testing for tuberculosis infection and screening for tuberculosis disease among refugees arriving in European countries from Ukraine. 2022. https:\u002F\u002Fwww.ecdc.europa.eu\u002Fen\u002Fpublications-data\u002Ftestingtuberculosis-infection-and-screening-tuberculosis-diseaseamong-displaced.\nEuropean Centre for Disease Prevention and Control. Operational public health considerations for the prevention and control of infectious diseases in the context of Russia’s aggression towards Ukraine, 2022(https:\u002F\u002Fwww.ecdc.europa.eu\u002Fsites\u002Fdefault\u002Ffiles\u002Fdocuments\u002FOperational-considerations-Russia-aggression-towards-Ukraine-final.pdf)\nHargreaves S, Lönnroth K, Nellums LB, et al. Multidrug-resistant tuberculosis and migration to Europe. Clin Microbiol Infect. 2017;23(3):141–6. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.cmi.2016.09.009.\nvan der Werf MJ, Zellweger JP. Impact of migration on tuberculosis epidemiology and control in the EU\u002FEEA. Euro Surveill. 2016;21(12):30174. https:\u002F\u002Fdoi.org\u002F10.2807\u002F1560-7917.ES.2016.21.12.30174.\nBoudville DA, Joshi R, Rijkers GT. Migration and tuberculosis in Europe. J Clin Tuberc Other Mycobact Dis. 2020;18:100143. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.jctube.2020.100143.\nNahid P, Dorman SE, Alipanah N, et al. Official American thoracic society\u002Fcenters for disease control and prevention\u002Finfectious diseases society of America clinical practice guidelines: treatment of drug-susceptible tuberculosis. Clin Infect Dis. 2016;63(7):e147–95. https:\u002F\u002Fdoi.org\u002F10.1093\u002Fcid\u002Fciw376.\nWorld Health Organization. Treatment of drug-susceptible tuberculosis: rapid communication. World Health Organization.; 2021. https:\u002F\u002Fapps.who.int\u002Firis\u002Fhandle\u002F10665\u002F341729\nDorman SE, Nahid P, Kurbatova EV, et al. High-dose rifapentine with or without moxifloxacin for shortening treatment of pulmonary tuberculosis: Study protocol for TBTC study 31\u002FACTG A5349 phase 3 clinical trial. Contemp Clin Trials. 2020;90:105938.\nDorman SE, Nahid P, Kurbatova EV, et al. Four-month rifapentine regimens with or without moxifloxacin for tuberculosis. N Engl J Med. 2021;384(18):1705–18.\nMeeting report of the WHO expert consultation on the definition of extensivelydrug-resistant tuberculosis, 27-29 October 2020. Geneva: World Health Organization; 2021.\n• Black TA, Buchwald UK. The pipeline of new molecules and regimens against drug-resistant tuberculosis. J Clin Tuberc Other Mycobact Dis. 2021;25:100285. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.jctube.2021.100285. The authors reviewed the new drugs and the current trials about TB treatment.\nMitchison D, Davies G. The chemotherapy of tuberculosis: past, present and future. Int J Tuberc Lung Dis. 2012;16(6):724–32. https:\u002F\u002Fdoi.org\u002F10.5588\u002Fijtld.12.0083.\n•• WHO consolidated guidelines on tuberculosis. Module 4: treatment - drug-susceptible tuberculosis treatment. Geneva: World Health Organization; 2022. New guidelines about MDR-TB treatment.\nBerry C, du Cros P, Fielding K, et al. TB-PRACTECAL: study protocol for a randomised, controlled, open-label, phase II-III trial to evaluate the safety and efficacy of regimens containing bedaquiline and pretomanid for the treatment of adult patients with pulmonary multidrug-resistant tuberculosis. Trials. 2022;23(1):484. https:\u002F\u002Fdoi.org\u002F10.1186\u002Fs13063-022-06331-8.\nConradie F, Bagdasaryan TR, Borisov S, et al. Bedaquiline-pretomanid-linezolid regimens for drug-resistant tuberculosis. N Engl J Med. 2022;387(9):810–23. https:\u002F\u002Fdoi.org\u002F10.1056\u002FNEJMoa2119430.\nMoodley R, Godec TR, STREAM Trial Team. Short-course treatment for multidrug-resistant tuberculosis: the STREAM trials. Eur Respir Rev. 2016;25(139):29–35. https:\u002F\u002Fdoi.org\u002F10.1183\u002F16000617.0080-2015.\nGoodall RL, Sanders K, Bronson G, et al. Keeping up with the guidelines: design changes to the STREAM stage 2 randomised controlled non-inferiority trial for rifampicin-resistant tuberculosis. Trials. 2022;23(1):474. https:\u002F\u002Fdoi.org\u002F10.1186\u002Fs13063-022-06397-4.\nGoodall RL, Meredith SK, Nunn AJ, et al. Evaluation of two short standardised regimens for the treatment of rifampicin-resistant tuberculosis (STREAM stage 2): an open-label, multicentre, randomised, non-inferiority trial. Lancet. 2022;400:1858–68. https:\u002F\u002Fdoi.org\u002F10.1016\u002FS0140-6736(22)02078-5.\nConradie F, Diacon AH, Ngubane N, et al. Treatment of highly drug-resistant pulmonary tuberculosis. N Engl J Med. 2020;382(10):893–902. https:\u002F\u002Fdoi.org\u002F10.1056\u002FNEJMoa1901814.\nOelofse S, Esmail A, Diacon AH, Conradie F, et al. Pretomanid with bedaquiline and linezolid for drug-resistant TB: a comparison of prospective cohorts. Int J Tuberc Lung Dis. 2021;25(6):453–60.\nConradie F, et al. High rate of successful outcome treating highly resistant TB in the ZeNix study of pretomanid, bedaquiline and alternative doses and duration of linezolid. In: 11th IAS Conference on HIV Science 2021: B11: Tuberculosis and other mycobacteria: A-LB-IAS2021-02405.\nAparna Bahuguna A, Rawat DS. An overview of new antitubercular drugs, drug candidates, and their targets. Med Res Rev. 2020;40(1):263–92. https:\u002F\u002Fdoi.org\u002F10.1002\u002Fmed.21602. Epub 2019 Jun 28\nWallis RS, Dawson R, Friedrich SO, et al. Mycobactericidal activity of sutezolid (PNU-100480) in sputum (EBA) and blood (WBA) of patients with pulmonary tuberculosis. PLoS One. 2014;9(4):e94462.\nChoi Y, et al. Safety, tolerability and pharmacokinetics of 21 day multiple oral administration of a new oxazolidinone antibiotic, LCB01-0371, in healthy male subjects. J Antimicrob Chemother. 2018;73(1):183–90.\nCho YL. Delpazolid (LCB01-0371): Oxazolidinone antibiotic for MDR-TB, in 2018 working group on new TB drugs, annual meeting. The Hague: The Netherlands; 2018.",{"VOID":1806},"10.1007\u002Fs40475-023-00287-8","2025-01-20T07:26:49.451+00:00",[30],"https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs40475-023-00287-8",[1811,1826,1848,1868],{"id":1812,"sortIndex":32,"researcher":28,"roles":1813,"affiliations":1814,"properties":1823,"displayName":1825,"givenName":28,"familyName":28},"1f8e6ca6-36fa-42bb-8666-719242f161e0",[968],[1815],{"id":1816,"sortIndex":32,"affiliation":1817,"properties":28},"289e293b-87be-467f-85e7-296a4f829281",{"id":1816,"createTime":28,"updateTime":28,"relativeEntities":1818,"slug":28,"properties":1819,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1822,"statistic":28},[],{"title":1820},{"VI":1821},"SOD Malattie Infettive e Tropicali, AOU Careggi, Florence, Italy",[],{"title":1824},{"VI":1825},"Jessica Mencarini",{"id":1827,"sortIndex":40,"researcher":28,"roles":1828,"affiliations":1829,"properties":1845,"displayName":1847,"givenName":28,"familyName":28},"a85f96b4-2064-4fab-a866-bf2525da4187",[968],[1830,1836],{"id":1816,"sortIndex":32,"affiliation":1831,"properties":28},{"id":1816,"createTime":28,"updateTime":28,"relativeEntities":1832,"slug":28,"properties":1833,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1835,"statistic":28},[],{"title":1834},{"VI":1821},[],{"id":1837,"sortIndex":40,"affiliation":1838,"properties":1844},"a91016fe-f9eb-45f6-a336-7371d1194475",{"id":1837,"createTime":28,"updateTime":28,"relativeEntities":1839,"slug":28,"properties":1840,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1843,"statistic":28},[],{"title":1841},{"VI":1842},"Dipartimento di Medicina Sperimentale e Clinica, Unità Malattie Infettive, Università degli Studi di Firenze, Florence, Italy",[],{},{"title":1846},{"VI":1847},"Michele Spinicci",{"id":1849,"sortIndex":123,"researcher":28,"roles":1850,"affiliations":1851,"properties":1865,"displayName":1867,"givenName":28,"familyName":28},"77f782be-56ee-467a-9259-e7ccf84ab87b",[968],[1852,1858],{"id":1816,"sortIndex":32,"affiliation":1853,"properties":28},{"id":1816,"createTime":28,"updateTime":28,"relativeEntities":1854,"slug":28,"properties":1855,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1857,"statistic":28},[],{"title":1856},{"VI":1821},[],{"id":1837,"sortIndex":40,"affiliation":1859,"properties":1864},{"id":1837,"createTime":28,"updateTime":28,"relativeEntities":1860,"slug":28,"properties":1861,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1863,"statistic":28},[],{"title":1862},{"VI":1842},[],{},{"title":1866},{"VI":1867},"Lorenzo Zammarchi",{"id":1869,"sortIndex":42,"researcher":28,"roles":1870,"affiliations":1871,"properties":1885,"displayName":1887,"givenName":28,"familyName":28},"1b72143e-8ed5-4dca-9f2a-d44cbfaacd77",[968],[1872,1878],{"id":1816,"sortIndex":32,"affiliation":1873,"properties":28},{"id":1816,"createTime":28,"updateTime":28,"relativeEntities":1874,"slug":28,"properties":1875,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1877,"statistic":28},[],{"title":1876},{"VI":1821},[],{"id":1837,"sortIndex":40,"affiliation":1879,"properties":1884},{"id":1837,"createTime":28,"updateTime":28,"relativeEntities":1880,"slug":28,"properties":1881,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1883,"statistic":28},[],{"title":1882},{"VI":1842},[],{},{"title":1886},{"VI":1887},"Alessandro Bartoloni",{"url":1809,"publisher":1889,"properties":1934},{"id":868,"createTime":869,"updateTime":870,"relativeEntities":1890,"slug":872,"properties":1891,"entityType":25,"verifyStatus":880,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":32,"subjectFields":1894,"manageAffiliations":1903,"indexDatabases":1914,"url":28,"thumbnailPath":28,"statistic":1929,"gsStatistic":28,"type":55,"analyzePriority":28},[],{"issn":1892,"title":1893},{"VOID":875},{"EN":877},[1895,1899],{"id":883,"createTime":28,"updateTime":28,"relativeEntities":1896,"label":1897,"description":1898,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":886},{},{"id":889,"createTime":28,"updateTime":28,"relativeEntities":1900,"label":1901,"description":1902,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":892},{},[1904,1909],{"id":896,"createTime":28,"updateTime":28,"relativeEntities":1905,"slug":28,"properties":1906,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1908,"statistic":28},[],{"title":1907},{"EN":900},[902],{"id":904,"createTime":28,"updateTime":28,"relativeEntities":1910,"slug":28,"properties":1911,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1913,"statistic":28},[],{"title":1912},{"EN":908},[],[1915,1922],{"id":912,"indexDatabase":1916,"url":918,"indexYears":28,"academicFieldIds":1921,"indexDatabaseRanking":28},{"id":803,"createTime":28,"updateTime":28,"relativeEntities":1917,"label":1918,"description":1919,"key":810,"publicationTags":1920,"standard":28},[],{"EN":806,"VI":806},{"EN":808,"VI":809},[812,813],[920,921,922],{"id":924,"indexDatabase":1923,"url":930,"indexYears":931,"academicFieldIds":1928,"indexDatabaseRanking":935},{"id":775,"createTime":28,"updateTime":28,"relativeEntities":1924,"label":1925,"description":1926,"key":781,"publicationTags":1927,"standard":28},[],{"EN":778,"VI":778},{"EN":778,"VI":780},[783],[933,934],{"impactFactor":32,"impactFactorByYear":1930,"i10Index":32,"i10IndexLast5Year":32,"totalPublication":218,"totalPublicationByYear":1931,"totalCitation":32,"totalCitationByYear":1932,"totalCitationPerPublication":32,"totalCitationPerPublicationByYear":1933,"hindexLast5Year":32,"hindex":32},{},{"2013":42,"2014":146,"2015":205,"2016":199,"2017":130,"2018":128,"2019":126,"2020":145,"2021":128,"2022":127,"2023":127,"2024":40},{},{},{"pages":1935,"volume":1937},{"VOID":1936},"88-93",{"VOID":1676},"2023-05-27",[935,812],{"id":1941,"createTime":1942,"updateTime":1943,"relativeEntities":1944,"slug":1945,"properties":1946,"entityType":960,"verifyStatus":26,"verifyTime":1943,"verifyNote":962,"languages":28,"translateLanguages":28,"viewCount":40,"primaryUrl":1955,"fullTextUrl":28,"authors":1956,"publicationType":1083,"publisherRelationship":1972,"citationCount":28,"citationInfo":28,"publishDate":2023,"publishYear":2024,"citationAnalyzeStatus":880,"lastCitationAnalyze":28,"indexDatabases":2025,"openAccess":28,"references":28,"isForceReanalyzing":1138},"0a74614c-1183-4742-8945-ce83f3f9f8c3","2024-01-08T22:40:33.821+00:00","2024-12-15T12:48:46.014+00:00",[],"Neurocysticercosis-in-the-Tropics-and-Beyond-",{"abstract":1947,"title":1949,"references":1951,"doi":1953},{"EN":1948},"Human cysticercosis is caused by ingestion of Taenia solium eggs from asymptomatic taenia carriers and not by eating undercooked pork. Neurocysticercosis (NCC), a disease caused by the invasion of the CNS and its coverings by the larval stage of Taenia solium, has trespassed the boundaries of tropical regions and is the most common helminthic infection of the CNS worldwide. Here, recent advances in the diagnosis and management of NCC are discussed with attention to the introduction of modern neuroimaging techniques, sophisticated immune diagnostic tests, and studies focusing on the usefulness of cysticidal drugs. The most recent revision of the unified chart of diagnostic criteria for NCC will facilitate its diagnosis in different settings by providing easier operational definitions. From this chart, it is clear that neuroimaging studies are fundamental for NCC diagnosis, inasmuch as immunological test and clinical manifestations only provide circumstantial evidence of CNS infection. Recent studies provided level 1 evidence favoring the use of cysticidal drugs for therapy of patients with parenchymal NCC by showing disappearance of brain lesions and clinical improvement in most cases. Despite recent advances, the last word on diagnosis and management of NCC has not been said. Further validation of the revised chart of diagnostic criteria is desirable to assess its reliability in different scenarios. Also, randomized controlled trials for patients with subarachnoid, ventricular, and spinal NCC are urgently needed to increase the level of evidence supporting the different therapeutic approaches suggested for these forms of the disease.",{"EN":1950},"Neurocysticercosis in the Tropics (and Beyond)",{"VOID":1952},"Coyle CM. Neurocysticercosis: an update. Curr Infect Dis Rep. 2014;16:347. https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs11908-014-0437-6.\nGarcia HH. Parasitic infections of the nervous system. Continuum (Minneap Minn). 2021;27:943–62. https:\u002F\u002Fdoi.org\u002F10.1212\u002FCON.0000000000000986.\nGarcia HH, Del Brutto OH. Fake news in neglected tropical diseases: the case of neurocysticercosis. PLoS Negl Trop Dis. 2020;14(6):e0008208. https:\u002F\u002Fdoi.org\u002F10.1371\u002Fjournal.pntd.0008208.\nDel Brutto OH. Neurocysticercosis among international travelers to disease-endemic areas. J Travel Med. 2012;19:112–7. https:\u002F\u002Fdoi.org\u002F10.1111\u002Fj.1708-8305.2011.00592.x.\nHunter E, Cliff M, Armstrong M, Manji H, Jager HR, Chiodini P, et al. Active neurocysticercosis at the hospital for tropical diseases, London: a clinical case series. Trans R Soc Trop Med Hyg. 2018;112:326–34. https:\u002F\u002Fdoi.org\u002F10.1093\u002Ftrstmh\u002Ftry060.\nSchantz PM, Moore AC, Muñoz JL, Hartman BJ, Schaefer JA, Aron AM, et al. Neurocysticercosis in an Orthodox Jewish community in New York City. N Engl J Med. 1992;327:692–5. https:\u002F\u002Fdoi.org\u002F10.1056\u002FNEJM199209033271004.\nGarcia HH, Nash TE, Del Brutto OH. Clinical symptoms, diagnosis, and treatment of neurocysticercosis. Lancet Neurol. 2014;13:1202–15. https:\u002F\u002Fdoi.org\u002F10.1016\u002FS1474-4422(14)70094-8.\nMoyano LM, O’Neal SE, Ayvar V, Gonzalvez G, Gamboa R, Vílchez P, et al. High prevalence of asymptomatic neurocysticercosis in an endemic rural community in Perú. PloS Negl Trop Dis. 2016;10(12):e0005130. https:\u002F\u002Fdoi.org\u002F10.1371\u002Fjournal.pntd.0005130.\nFleury A, Gomez T, Alvarez I, Meza D, Huerta M, Chavarría A, et al. High prevalence of calcified silent neurocysticercosis in a rural village of Mexico. Neuroepidemiol. 2003;22:139–45. https:\u002F\u002Fdoi.org\u002F10.1159\u002F000068748.\nCarabin H, Ndimubanzi PC, Budke CM, Nguyen H, Qian Y, Cowan LD, et al. Clinical manifestations associated with neurocysticercosis: a systematic review. PLoS Negl Trop Dis. 2011;5(5):e1152. https:\u002F\u002Fdoi.org\u002F10.1371\u002Fjournal.pntd.0001152.\n• Nash TE, Mahanty S, Loeb JA, Theodore WH, Friedman A, Sander JW, et al. Neurocysticercosis: a natural human model of epileptogenesis. Epilepsia. 2015;56:177–83. https:\u002F\u002Fdoi.org\u002F10.1111\u002Fepi.12849. Comprehensive review of the complex mechanisms involved in NCC-related epileptogenesis.\nNash TE. Edema surrounding calcified intracranial cysticerci: clinical manifestations, natural history, and treatment. Pathog Glob Health. 2012;106:275–9. https:\u002F\u002Fdoi.org\u002F10.1179\u002F2047773212Y.0000000026.\nSingh G, Singh P, Singh I, Rani A, Kaushal S, Avasthi G. Epidemiologic classification of seizures associated with neurocysticercosis: observations from a sample of seizure disorders in neurologic care in India. Acta Neurol Scand. 2006;113:233–40. https:\u002F\u002Fdoi.org\u002F10.1111\u002Fj.1600-0404.2005.00575.x.\nDel Brutto OH, Engel J Jr, Eliashiv DS, Garcia HH. Update on cysticercosis epileptogenesis: the role of the hippocampus. Curr Neurol Neurosci Rep. 2016;16:1. https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs11910-015-0601-x.\n• Herrick JA, Bustos JA, Clapham P, García HH, Loeb JA, for the Cysticercosis Working Group in Perú. Unique characteristics of epilepsy development in neurocysticercosis. Am J Trop Med Hyg. 2020;103:639–45. https:\u002F\u002Fdoi.org\u002F10.4269\u002Fajtmh.19-0485. Updated review on potential mechanisms accounting for the occurrence of epilepsy among NCC patients.\nLachuriya G, Garg RK, Jain A, Malhotra HS, Singh AK, Jain B, et al. Toll-like receptor-4 polymorphisms and serum matrix metalloproteinase-9 in newly diagnosed patients with calcified neurocysticercosis and seizures. Med (Baltimore). 2016;95:e3288. https:\u002F\u002Fdoi.org\u002F10.1097\u002FMD.0000000000003288.\nPrasad A, Prasad KN, Gupta RK, Pradhan S. Increased expression of ICAM-1 among symptomatic neurocysticercosis. J Neuroimmunol. 2009;2009(206):118–20. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.jneuroim.2008.09.015.\nVerma A, Prasad KN, Gupta RK, Singh AK, Nyati KK, Rizwan A, et al. Toll-like receptor 4 polymorphism and its association with symptomatic neurocysticercosis. J Infect Dis. 2010;202:1219–25. https:\u002F\u002Fdoi.org\u002F10.1086\u002F656395.\nHerrick JA, Maharathi B, Kim JS, Abundis GG, Garg A, Gonzales I, et al. Inflammation is a key risk factor for persistent seizures in neurocysticercosis. Ann Clin Transl Neurol. 2018;5:630–9. https:\u002F\u002Fdoi.org\u002F10.1002\u002Facn3.562.\nDel Brutto OH, Arroyo G, Del Brutto VJ, Zambrano M, García HH. On the relationship between calcified neurocysticercosis and epilepsy in an endemic village: a large-scale, computed tomography-based population study in rural Ecuador. Epilepsia. 2017;58:1955–61. https:\u002F\u002Fdoi.org\u002F10.1111\u002Fepi.13892.\nDel Brutto OH, Mera RM. Atahualpa Project Investigators The importance of people compliance (social desirability bias) in the assessment of epilepsy prevalence in rural areas of developing countries Results of the Atahualpa Project. Epilepsia. 2016;57:e221-4. https:\u002F\u002Fdoi.org\u002F10.1111\u002Fepi.13594.\n• Del Brutto OH, Recalde BY, Mera RM. Incidence of adult-onset epilepsy and the contributory role of neurocysticercosis in a five-year, population-based, prospective study in rural Ecuador. Am J Trop Med Hyg. 2021. https:\u002F\u002Fdoi.org\u002F10.4269\u002Fajtmh.21-0835. Longitudinal study showing a high incidence of adult-onset epilepsy in rural Ecuador and the causal impact of NCC, accounting for one-third of these cases.\nGarvey BT, Moyano LM, Ayvar V, Rodriguez S, Gilman RH, Gonzalez AE, et al. Neurocysticercosis among people living near pigs heavily infected with cysticercosis in rural endemic Perú. Am J Trop Med Hyg. 2018;98:558–64. https:\u002F\u002Fdoi.org\u002F10.4269\u002Fajtmh.17-0443.\nPrasad KN, Prasad A, Gupta RK, Nath K, Pradhan S, Tripathi M, et al. Neurocysticercosis in patients with active epilepsy from the pig farming community of Lucknow district, north India. Trans R Soc Trop Med Hyg. 2009;103:144–50. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.trstmh.2008.07.015.\nGarcía HH, Gonzalez AE, Gilman RH. Neurocysticercosis as an eradicable cause of epilepsy: a plan and actions are needed. JAMA Neurol. 2021;78:1045–6. https:\u002F\u002Fdoi.org\u002F10.1001\u002Fjamaneurol.2021.2349.\nGarcia HH, Gonzalez AE, Tsang VC, O’Neal SE, Llanos-Zavalaga F, Gonzalvez G, et al. Elimination of Taenia solium transmission in northern Perú. N Engl J Med. 2016;374:2335–44. https:\u002F\u002Fdoi.org\u002F10.1056\u002FNEJMoa1515520.\nDel Brutto OH, O’Neal SE, Dorny P, García HH. Spontaneously arrested transmission of cysticercosis in a highly endemic village with a very low migration rate. Am J Trop Med Hyg. 2018;98:776–8. https:\u002F\u002Fdoi.org\u002F10.4269\u002Fajtmh.17-0723.\nDel Brutto OH, Del Brutto VJ. Calcified neurocysticercosis among patients with primary headache. Cephalalgia. 2012;32:250–4. https:\u002F\u002Fdoi.org\u002F10.1177\u002F0333102411433043.\nDel Brutto OH, Robles AM, Mera RM, Costa AF, Darsan E, Milla L, et al. Calcified neurocysticercosis and headache in an endemic village: a case-control study nested to a population-based cohort. Am J Trop Med Hyg. 2018;99:729–34. https:\u002F\u002Fdoi.org\u002F10.4269\u002Fajtmh.18-0310.\nNash TE, Pretell EJ, Lescano AG, Bustos JA, Gilman RH, Gonzalez AE, et al. Perilesional brain oedema and seizure activity in patients with calcified neurocysticercosis: a prospective cohort and nested case-control study. Lancet Neurol. 2008;7:1099–105. https:\u002F\u002Fdoi.org\u002F10.1016\u002FS1474-4422(08)70243-6.\nFleury A, Carrillo-Mezo R, Flisser A, Sciutto E, Corona T. Subarachnoid basal neurocysticercosis: a focus on the most severe form of the disease. Expert Rev Anti-Infect Ther. 2011;9:123–33. https:\u002F\u002Fdoi.org\u002F10.1586\u002Feri.10.150.\nCarod Artal FJ. Clinical management of infectious cerebral vasculitidis. Expert Rev Neurother. 2016;16:205–21. https:\u002F\u002Fdoi.org\u002F10.1586\u002F14737175.2015.1134321.\nDel Brutto OH, Mera RM, Zambrano M, Costa AF, Román GC. The association between calcified neurocysticercosis and cognitive performance: a case-control study nested to a population-based cohort. Am J Trop Med Hyg. 2019;100:323–6. https:\u002F\u002Fdoi.org\u002F10.4269\u002Fajtmh.18-0611.\nDel Brutto OH, Del Brutto VJ. Intrasellar cysticercosis: a systematic review. Acta Neurol Belg. 2013;113:225–7. https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs13760-013-0199-1.\nDel Brutto OH, García HH. Intramedullary cysticercosis of the spinal cord: a review of patients evaluated with MRI. J Neurol Sci. 2013;331:114–7. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.jns.2013.05.025.\nReddy S, Panchal B, Pathengay A. Relationship between scolex, shape of the cyst and timing of surgery in subretinal cysticercosis. BMJ Case Rep. 2020;13:e236805. https:\u002F\u002Fdoi.org\u002F10.1136\u002Fbcr-2020-236805.\nGuzman C, Garcia HH. Cysticercosis Working Group in Peru. Current diagnostic criteria for neurocysticercosis. Res Rep Trop Med. 2021;12:197–203. https:\u002F\u002Fdoi.org\u002F10.2147\u002FRRTM.S285393.\nKimura-Hayama ET, Higuera JA, Corona-Cedillo R, Chávez-Macías L, Perochena A, Quiroz-Rojas LY, et al. Neurocysticercosis: radiologic-pathologic correlation. Radiographics. 2010;30:1705–19. https:\u002F\u002Fdoi.org\u002F10.1148\u002Frg.306105522.\nPappala BCS, Indugula JP, Shrivastava AK, Jumar S, Talabhatula SK, Kolli RS, et al. Comparative evaluation of indigenous ELISAs for detection of anti-cysticercus IgG antibodies in serum from clinically and radiologically suspected cases of neurocysticercosis. Trop Biomed. 2017;34:622–35.\nCarod JF, Randrianarison M, Razafimahefa J, Ramahefarisoa RM, Rakotondrazaka M, Debruyne M. Evaluation of the performance of 5 commercialized enzyme immunoassays for the detection of Taenia solium antibodies and for the diagnosis of neurocysticercosis. Diagn Microbiol Infect Dis. 2012;72:85–9. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.diagmicrobio.2011.09.014.\nGarcía HH, Castillo Y, Gonzales I, Bustos JA, Saavedra H, Jacob L, et al. Low sensitivity and frequent cross-reactions in commercially available antibody detection ELISA assays for Taenia solium cysticercosis. Trop Med Int Health. 2018;23:101–5. https:\u002F\u002Fdoi.org\u002F10.1111\u002Ftmi.13010.\nRodriguez S, Wilkins P, Dorny P. Immunological and molecular diagnosis of cysticercosis. Pathog Glob Health. 2012;106:286–98. https:\u002F\u002Fdoi.org\u002F10.1179\u002F2047773212Y.0000000048.\nWebb CM, White AC Jr. Update on the diagnosis and management of neurocysticercosis. Curr Infect Dis Rep. 2016;18:44. https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs11908-016-0547-4.\n• Garcia HH, O’Neal SE, Noh J, Handali S, for The Cysticercosis Working Group in Peru. Laboratory diagnosis of neurocysticercosis (Taenia solium). J Clin Microbiol. 2018;56:e00424–18. https:\u002F\u002Fdoi.org\u002F10.1128\u002FJCM.00424-18. Updated review on the different immunodiagnostic assays for the diagnosis of Taenia solium cysticercosis and their reliability.\nArroyo G, Bustos JA, Lescano AG, Gonzales I, Saavedra H, Pretell EJ, et al. Improved diagnosis of viable parenchymal neurocysticercosis by combining antibody bandings patterns on enzyme-linked immunoelectrotransfer blot (EITB) with antigen ELISA assay. J Clin Microbiol. https:\u002F\u002Fdoi.org\u002F10.1128\u002FJCM.01550-21.\nO’Connell EM, Harrison S, Dahlstrom E, Nash T, Nutman TB. A novel, highly sensitive quantitative polymerase chain reaction assay for the diagnosis of subarachnoid and ventricular neurocysticercosis and for assessing responses to treatment. Clin Infect Dis. 2020;70:1875–81. https:\u002F\u002Fdoi.org\u002F10.1093\u002Fcid\u002Fciz541.\nDel Brutto OH, Wadia NH, Dumas M, Cruz M, Tsang VC, Schantz PM. Proposal of diagnostic criteria for human cysticercosis and neurocysticercosis. J Neurol Sci. 1996;142:1–6. https:\u002F\u002Fdoi.org\u002F10.1016\u002F0022-510x(96)00130-x.\nDel Brutto OH, Rajshekhar V, White AC Jr, Nash TE, Takayanagui OM, Schantz PM, et al. Proposed diagnostic criteria for neurocysticercosis. Neurology. 2001;57:177–83. https:\u002F\u002Fdoi.org\u002F10.1212\u002Fwnl.57.2.177.\n• Del Brutto OH, Nash TE, White AC Jr, Rajshekhar V, Wilkins PP, Singh G, et al. Revised diagnostic criteria for neurocysticercosis. J Neurol Sci. 2017;371:202–10. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.jns.2016.11.045. Last revised version of the unified diagnostic criteria for neurocysticercosis, based on two principles: neuroimaging studies are essential for the diagnosis of NCC, while clinical and exposure data only provide circumstantial evidence favoring the diagnosis.\nDel Brutto OH. Twenty-five years of evolution of standard diagnostic criteria for neurocysticercosis How have they impacted diagnosis and patient outcomes? Expert Rev Neurother. 2020;20:147–55. https:\u002F\u002Fdoi.org\u002F10.1080\u002F14737175.2020.1707667.\nGarg RK. Diagnostic criteria for neurocysticercosis: some modifications are needed for Indian patients. Neurol India. 2004;52(2):171–7.\nGabriel S, Blocher J, Dorny P, Abatih EN, Schmutzhard E, Ombay M, et al. Added value of antigen ELISA in the diagnosis of neurocysticercosis in resource poor settings. PLoS Negl Trop Dis. 2012;6(10):e1851. https:\u002F\u002Fdoi.org\u002F10.1371\u002Fjournal.pntd.0001851.\nCarpio A, Fleury A, Romo ML, Abraham R, Fandiño J, Durán JC, et al. New diagnostic criteria for neurocysticercosis: reliability and validity. Ann Neurol. 2016;80:434–42. https:\u002F\u002Fdoi.org\u002F10.1002\u002Fana.24732.\nGilman RH. Infectious disease: diagnostic criteria for neurocysticercosis – a difficult update. Nat Rev Neurol. 2016;12:560–1. https:\u002F\u002Fdoi.org\u002F10.1038\u002Fnrneurol.2016.145.\n• Coyle CM. Neurocysticercosis: an individualized approach. Infect Dis Clin North Am. 2019;33:153–68. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.idc.2018.10.007. Treatment of neurocysticercosis must be individualized according to the number of location of lesions, severity of the host’s immune response to the parasites, and viability of parasites.\nDel Brutto OH. Twenty-five years of evolution of standard diagnostic criteria for neurocysticercosis. How have they impacted diagnosis and patients outcomes? Expert Rev Neurother. 2020;20:147–55. https:\u002F\u002Fdoi.org\u002F10.1080\u002F14737175.2020.1707667.\nBustos JA, Garcia HH, Del Brutto OH. Antiepileptic drug therapy and recommendations for withdrawal in patients with seizures and epilepsy due to neurocysticercosis. Expert Rev Neurother. 2016;16:1079–85. https:\u002F\u002Fdoi.org\u002F10.1080\u002F14737175.2016.1194757.\nNash TE, Mahanty S, Garcia HH, Cysticercosis Group in Peru. Corticosteroid use in neurocysticercosis. Expert Rev Neurother. 2011;11:1175–83. https:\u002F\u002Fdoi.org\u002F10.1586\u002Fern.11.86.\nMitre E, Talaat KR, Sperling MR, Nash TE. Methotrexate as a corticosteroid-sparing agent in complicated neurocysticercosis. Clin Infect Dis. 2007;44:549–53. https:\u002F\u002Fdoi.org\u002F10.1086\u002F511040.\nNash TE, Ware JAM, Coyle CM, Mahanty S. Etanercept to control inflammation in the treatment of complicated neurocysticercosis. Am J Trop Med Hyg. 2019;100:609–16. https:\u002F\u002Fdoi.org\u002F10.4269\u002Fajtmh.18-0795.\nBarrie U, Badejo O, Aoun SG, Adeyemo E, Moler N, Christian ZK, et al. Systematic review and meta-analysis of management strategies and outcomes in adult spinal neurocysticercosis. World Neurosurg. 2020;138:504-11e8. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.wneu.2020.03.093.\nHamamoto Filho PT, Zanini MA, Fleury A. Hydrocephalus in neurocysticercosis: challenges for clinical practice and basic research perspectives. World Neurosurg. 2019;126:264–71. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.wneu.2019.03.071.\n• Nash TE, Ware JAM, Mahanty S. Intraventricular neurocysticercosis: experience and long-term outcome from a tertiary referral center in the United States. Am J Trop Med Hyg. 2018;98:1755–62. https:\u002F\u002Fdoi.org\u002F10.4269\u002Fajtmh.18-0085. Large series of patients with intraventricular neurocysticercosis describing in detail treatment options and outcome.\nDel Brutto OH. A personal account regarding the origin and evolution of controversies in the management of neurocysticercosis. Am J Trop Med Hyg. 2019;100:780–2. https:\u002F\u002Fdoi.org\u002F10.4269\u002Fajtmh.18-0921.\nGarcia HH, Pretell EJ, Gilman RH, et al. A trial of antiparasitic treatment to reduce the rate of seizures due to cerebral cysticercosis. N Engl J Med. 2004;350:249–58. https:\u002F\u002Fdoi.org\u002F10.1056\u002FNEJMoa031294.\nDel Brutto OH, Roos KL, Coffey CS, Garcia HH. Meta-analysis: cysticidal drugs for neurocysticercosis: albendazole and praziquantel. Ann Intern Med. 2006;145:43–51. https:\u002F\u002Fdoi.org\u002F10.7326\u002F0003-4819-145-1-200607040-00009.\nBaird RA, Wiebe S, Zunt JR, Halperin JJ, Gronseth G, Roos KL. Evidence-based guideline: treatment of parenchymal neurocysticercosis: report of the guideline development subcommittee of the American Academy of Neurology. Neurol. 2013;80:1424–9. https:\u002F\u002Fdoi.org\u002F10.1212\u002FWNL.0b013e31828c2f3e.\nDel Brutto OH, García HH. The many facets of disseminated parenchymal brain cysticercosis: a differential diagnosis with important therapeutic implications. PloS Negl Trop Dis. 2021;15:e0009883. https:\u002F\u002Fdoi.org\u002F10.1371\u002Fjournal.pntd.0009883.\nNash TE, O’Connell EM, Hammoud DA, Wetzler L, Ware JM, Mahanty S. Natural history of treated subarachnoid neurocysticercosis. Am J Trop Med Hyg. 2020;102:78–89. https:\u002F\u002Fdoi.org\u002F10.4269\u002Fajtmh.19-0436.\n•• White AC, Coyle CM, Rajshekhar V, et al. Diagnosis and treatment of neurocysticercosis: 2017 clinical practice guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH). Clin Infect Dis. 2018;66:1159–63. https:\u002F\u002Fdoi.org\u002F10.1093\u002Fcid\u002Fcix1084. Updated guidelines for diagnosis and treatment of neurocysticercosis.\n•• Garcia HH, Gonzales I, Lescano AG, Bustos JA, Zimic M, Escalante D, et al. Efficacy of combined antiparasitic therapy with praziquantel and albendazole for neurocysticercosis: a double-blind, randomised controlled trial. Lancet Infect Dis. 2014;14:687–95. https:\u002F\u002Fdoi.org\u002F10.1016\u002FS1473-3099(14)70779-0. Study proving level 1 evidence on the value of combined cysticidal therapy for patients with more than two viable cysts in the brain parenchyma.\nGarcía HH, Lescano AG, Gonzales I, et al. Cysticidal efficacy of combined treatment with praziquantel and albendazole for parenchymal brain cysticercosis. Clin Infect Dis. 2016;62:1375–9. https:\u002F\u002Fdoi.org\u002F10.1093\u002Fcid\u002Fciw134.\nBustos JA, Garcia HH, Del Brutto OH. Reliability of diagnostic criteria for neurocysticercosis for patients with ventricular cystic lesions of granulomas: a systematic review. Am J Trop Med Hyg. 2017;97:653–7. https:\u002F\u002Fdoi.org\u002F10.4269\u002Fajtmh.17-0069.\nNash TE, Del Brutto OH, Butman JA, Corona T, Delgado Escueta A, Duron RM, et al. Calcific neurocysticercosis and epileptogenesis. Neurol. 2004;62:1934–8. https:\u002F\u002Fdoi.org\u002F10.1212\u002F01.wnl.0000129481.12067.06.\nBianchin MM, Rodrigues Velasco T, Wichert-Ana L, Dos Santos AC, Sakamoto AC. Understanding the association of neurocysticercosis and mesial temporal lobe epilepsy and its impact on the surgical treatment of patients with drug-resistant epilepsy. Epilepsy Behav. 2017;76:168–77. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.yebeh.2017.02.030.",{"VOID":1954},"10.1007\u002Fs40475-022-00269-2","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs40475-022-00269-2",[1957],{"id":1958,"sortIndex":32,"researcher":28,"roles":1959,"affiliations":1960,"properties":1969,"displayName":1971,"givenName":28,"familyName":28},"535dc38b-40a4-4b6b-8492-e4decb024364",[968],[1961],{"id":1962,"sortIndex":32,"affiliation":1963,"properties":28},"6a620257-554c-422a-b777-8c7404a650d2",{"id":1962,"createTime":28,"updateTime":28,"relativeEntities":1964,"slug":28,"properties":1965,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1968,"statistic":28},[],{"title":1966},{"VI":1967},"School of Medicine and Research Center, Universidad Espíritu Santo – Ecuador, Urbanización Toscana, Samborondón, Ecuador",[],{"title":1970},{"VI":1971},"Oscar H. Del Brutto",{"url":1955,"publisher":1973,"properties":2018},{"id":868,"createTime":869,"updateTime":870,"relativeEntities":1974,"slug":872,"properties":1975,"entityType":25,"verifyStatus":880,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":32,"subjectFields":1978,"manageAffiliations":1987,"indexDatabases":1998,"url":28,"thumbnailPath":28,"statistic":2013,"gsStatistic":28,"type":55,"analyzePriority":28},[],{"issn":1976,"title":1977},{"VOID":875},{"EN":877},[1979,1983],{"id":883,"createTime":28,"updateTime":28,"relativeEntities":1980,"label":1981,"description":1982,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":886},{},{"id":889,"createTime":28,"updateTime":28,"relativeEntities":1984,"label":1985,"description":1986,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":892},{},[1988,1993],{"id":896,"createTime":28,"updateTime":28,"relativeEntities":1989,"slug":28,"properties":1990,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1992,"statistic":28},[],{"title":1991},{"EN":900},[902],{"id":904,"createTime":28,"updateTime":28,"relativeEntities":1994,"slug":28,"properties":1995,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1997,"statistic":28},[],{"title":1996},{"EN":908},[],[1999,2006],{"id":912,"indexDatabase":2000,"url":918,"indexYears":28,"academicFieldIds":2005,"indexDatabaseRanking":28},{"id":803,"createTime":28,"updateTime":28,"relativeEntities":2001,"label":2002,"description":2003,"key":810,"publicationTags":2004,"standard":28},[],{"EN":806,"VI":806},{"EN":808,"VI":809},[812,813],[920,921,922],{"id":924,"indexDatabase":2007,"url":930,"indexYears":931,"academicFieldIds":2012,"indexDatabaseRanking":935},{"id":775,"createTime":28,"updateTime":28,"relativeEntities":2008,"label":2009,"description":2010,"key":781,"publicationTags":2011,"standard":28},[],{"EN":778,"VI":778},{"EN":778,"VI":780},[783],[933,934],{"impactFactor":32,"impactFactorByYear":2014,"i10Index":32,"i10IndexLast5Year":32,"totalPublication":218,"totalPublicationByYear":2015,"totalCitation":32,"totalCitationByYear":2016,"totalCitationPerPublication":32,"totalCitationPerPublicationByYear":2017,"hindexLast5Year":32,"hindex":32},{},{"2013":42,"2014":146,"2015":205,"2016":199,"2017":130,"2018":128,"2019":126,"2020":145,"2021":128,"2022":127,"2023":127,"2024":40},{},{},{"pages":2019,"volume":2021},{"VOID":2020},"119-129",{"VOID":2022},"9","2022-10-01",2022,[935,812],{"id":2027,"createTime":2028,"updateTime":2029,"relativeEntities":2030,"slug":2031,"properties":2032,"entityType":960,"verifyStatus":26,"verifyTime":2029,"verifyNote":962,"languages":28,"translateLanguages":28,"viewCount":32,"primaryUrl":2041,"fullTextUrl":28,"authors":2042,"publicationType":1083,"publisherRelationship":2058,"citationCount":28,"citationInfo":28,"publishDate":2108,"publishYear":1136,"citationAnalyzeStatus":880,"lastCitationAnalyze":28,"indexDatabases":2109,"openAccess":28,"references":28,"isForceReanalyzing":1138},"0ad8345e-b062-493c-a63c-f2f23f370572","2024-01-26T20:54:01.021+00:00","2025-02-02T02:51:08.043+00:00",[],"Giardiasis-and-Zinc-Absorption",{"abstract":2033,"title":2035,"references":2037,"doi":2039},{"EN":2034},"\n                           Giardia lamblia is recognized as a one of the most prevalent protozoa and a frequent cause of gastroenteritis, but there is also increasing evidence of extra-intestinal manifestations and long-term complications after its clearance. Additionally, giardiasis has also been associated with a reduction in zinc absorption and other essential minerals. This article reviews the linking between Giardia and zinc absorption. Malabsorption of macro- and micronutrients is a well-known condition in chronic giardiasis. The precise mechanism to blame is not clear yet, but it is definitely more complex than the inflammatory response observed in other infections. \n                           Giardia affects the host in various forms, causing a wide spectrum of symptoms or as an asymptomatic condition too. Zinc deficiency has a high prevalence in children from developing countries and this condition can be attributed to several factors, including low intake and poor absorption. The association between zinc malabsorption and giardiasis has been established; however, the mechanism responsible remains unclear.",{"EN":2036},"Giardiasis and Zinc Absorption",{"VOID":2038},"Black RE, Morris SSM, Bryce J. Where and why are 10 million children dying every year? Lancet [Internet]. 2003;361:2226–34. Available from: http:\u002F\u002Fwww.thelancet.com\u002Fpdfs\u002Fjournals\u002Flancet\u002FPIIS0140-6736(03)13779-8.pdf\nUNICEF. Committing to child survival: a promise renewed. 2015.\n• Cm Halliez M, Buret AG. Extra-intestinal and long term consequences of Giardia duodenalis infections. World J Gastroenterol [Internet]. 2013; 19(47). Available from: http:\u002F\u002Fwww.wjg-net.com\u002F1007-9327\u002Ffull\u002Fv19\u002Fi47\u002F8974.htm. This article summarizes extra-intestinal and long term complications of giardiasis.\nYaoyu F, Xiao L. Zoonotic potential and molecular epidemiology of Giardia species and giardiasis. Clin Microbiol Rev. 2011;24(1):110–40.\nBartelt LA, Sartor RB. Advances in understanding Giardia: determinants and mechanisms of chronic sequelae. F1000Prime Rep [Internet]. 2015; 62(7). Available from: http:\u002F\u002Ff1000.com\u002Fprime\u002Freports\u002Fb\u002F7\u002F62.\nHellard ME, Sinclair MI, Hogg GG, Fairley CK. Prevalence of enteric pathogens among community based asymptomatic individuals. J Gastroenterol Hepatol [Internet]. 2000;15(3):290–3. Available from: http:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F10764030\nArbabi M, Esmaili N, Parastouei K, Hooshyar H, Rasti S. Levels of zinc, copper, magnesium elements, and vitamin B12, in sera of school children with Giardiasis and Entrobiosis in Kashan, Iran. Zahedan J Res Med Sci. 2015;15:29–32.\nDonowitz JR, Alam M, Kabir M, Ma JZ, Nazib F, Platts-Mills JA, et al. A prospective longitudinal cohort to investigate the effects of early life Giardiasis on growth and all cause diarrheas. Clin Infect Dis [Internet]. 2016;63:792–7. Available from: https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC4996141\u002Fpdf\u002Fciw391.pdf\nÇelgksös A, Aciöz M, Deerlg S, Çinar Z, Elaldi N, Erandac M. Effects of Giardiasis on school success, weight and height indices of primary school children in Turkey. Pediatr Int. 2005;47(5):567–71.\nChen T-L, Chen S, Wu H-W, Lee T-C, Lu Y-Z, Wu L-L, et al. Persistent gut barrier damage and commensal bacterial influx following eradication of Giardia infection in mice. Gut Pathogens. 2013;5(26):1–12. Available from: https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC3765889\u002Fpdf\u002F1757-4749-5-26.pdf\nHanevik K, Wensaas K-A, Rortveit G, Eide GE, Mørch K, Langeland N. Irritable bowel syndrome and chronic fatigue 6 years after giardia infection: a controlled prospective cohort study. Clin Infect Dis [Internet]. 2014;59(10):1394–400. Available from: http:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F25115874\nWensaas K-A, Langeland N, Hanevik K, Mørch K, Eide GE, Rortveit G. Irritable bowel syndrome and chronic fatigue 3 years after acute giardiasis: historic cohort study. Gut [Internet]. 2012;61(2):214–9. Available from: http:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F21911849\nAstiazarán-García H, Iñigo-Figueroa G, Quihui-Cota L, Anduro-Corona I. Crosstalk between zinc status and Giardia infection: a new approach. Nutrients [Internet]. 2015;7:4438–52. Available from: http:\u002F\u002Fwww.mdpi.com\u002Fjournal\u002Fnutrients\n•• Hara T, Takeda T, Takagishi T, Fukue K, Kambe T, Fukada T. Physiological roles of zinc transporters: molecular and genetic importance in zinc homeostasis. J Physiol Sci [Internet]. 2017;67(2):283–301. Available from: http:\u002F\u002Flink.springer.com\u002F10.1007\u002Fs12576-017-0521-4. This article includes recent and important evidence of Zinc transporters.\nRyan U, Cacciò SM. Zoonotic potential of Giardia. Int J Parasitol [Internet]. 2013;43(12):943–56. Available from: http:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS0020751913001720\nBerrilli F, Di Cave D, Cavallero S, D’Amelio S. Interactions between parasites and microbial communities in the human gut. Front Cell Infect Microbiol [Internet]. 2012;2:141. Available from: http:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F23162802\nBhargava A, Cotton JA, Dixon BR, Gedamu L, Yates RM, Buret AG. Giardia duodenalis surface cysteine proteases induce cleavage of the intestinal epithelial cytoskeletal protein villin via myosin light chain kinase. Bogyo M, editor. PLoS One [Internet]. 2015;10(9):e0136102. Available from: http:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F26334299.\n•• Beatty JK, Akierman SV, Motta J-P, Muise S, Workentine ML, Harrison JJ, et al. Giardia duodenalis induces pathogenic dysbiosis of human intestinal microbiota biofilms. Int J Parasitol [Internet]. 2017;47(6):311–26. Available from: http:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F28237889. This article is very important because its studies how Giardia could induce dysbiosis of microbiota biofilms.\nAmat C, Motta J-P, Bhargava A, Chadee K, Buret A. Giardia duodenalis depletes goblet cell mucins and degrades muc2, facilitating bacterial translocation. The FASEB Journal. [Internet]. 2015;29(1). Available from: http:\u002F\u002Fwww.fasebj.org\u002Fcontent\u002F29\u002F1_Supplement\u002F507.1.\nPrasad AS. Impact of the discovery of human zinc deficiency on health. J Trace Elem Med Biol [Internet]. 2014;28(4):357–63. Available from: http:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS0946672X14001710\nHojyo S, Fukada T. Zinc transporters and signaling in physiology and pathogenesis. Arch Biochem Biophys [Internet]. 2016;611:43–50. Available from: http:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F27394923\nLee HH, Prasad AS, Brewer GJ, Owyang C. Zinc absorption in human small intestine. Am J Physiol - Gastrointest Liver Physiol [Internet]. 1989;256(1). Available from: http:\u002F\u002Fajpgi.physiology.org\u002Fcontent\u002F256\u002F1\u002FG87.\nAndersen O, Nielsen JB, Sorensen JA, Scherrebeck L. Experimental localization of intestinal uptake sites for metals (cd, hg, Zn, se) in vivo in mice. Environ Health Perspect [Internet]. 1994;102(3):199–206. Available from: https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC1567371\u002Fpdf\u002Fenvhper00399-0194.pdf\nLönnerdal B. Zinc and health : current status and future directions dietary factors influencing zinc absorption. Am Soc Nutr Sci. 2000;1378–83.\nMiller LV, Krebs NF, Hambidge KM. Mathematical model of zinc absorption: effects of dietary calcium, protein and iron on zinc absorption. Br J Nutr. 2013;109(4):695–700. Available from: https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC3683099\u002Fpdf\u002Fnihms-449766.pdf\nPabón ML, Lönnerdal B. Effect of citrate on zinc bioavailability from milk, milk fractions and infant formulas. Nutr Res [Internet]. 1993;13(1):103–11. Available from: http:\u002F\u002Flinkinghub.elsevier.com\u002Fretrieve\u002Fpii\u002FS027153170580661X\nYoung GP, Mortimer EK, Gopalsamy GL, Alpers DH, Binder HJ, Manary MJ, et al. Zinc deficiency in children with environmental enteropathy—development of new strategies: report from an expert workshop. Am J of Clin Nut. 2014;100:1198–207.\nNadimi H, Yousefi Nejad A, Djazayery A, Hosseini M, Hosseini S, Mangels AR, et al. Dietary iron intake and iron status of German female vegans: results of the German vegan study. Am J Clin Nutr [Internet]. 2009;100(3):311–8. Available from: http:\u002F\u002Fwww.nutritionj.com\u002Fcontent\u002F14\u002F1\u002F115%5Cnhttp:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F19571226%5Cnhttp:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F24898231\nCuevas LE, Koyanagi A. Zinc and infection: a review. Ann Trop Paediatr [Internet]. 2005;25(3):149–60. Available from: http:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F16156979\nBlack RE, Victora CG, Walker SP, Bhutta ZA, Christian P, de Onis M, et al. Maternal and child undernutrition and overweight in low-income and middle-income countries. Lancet [Internet]. 2013;382(9890):427–51. Available from: http:\u002F\u002Flinkinghub.elsevier.com\u002Fretrieve\u002Fpii\u002FS014067361360937X\nTuerk MJ, Fazel N. Zinc deficiency. Curr Opin Gastroenterol [Internet]. 2009;25(2):136–43. Available from: http:\u002F\u002Fcontent.wkhealth.com\u002Flinkback\u002Fopenurl?sid=WKPTLP:landingpage&an=00001574-200903000-00009\nKogan S, Sood A, Garnick MS. Zinc and wound healing: a review of zinc physiology and clinical applications. Wounds a Compend Clin Res Pract [Internet]. 2017;29(4):102–6. Available from: http:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F28448263\nPrasad AS. 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Available from: http:\u002F\u002Fwww.scirp.org\u002Fjournal\u002FPaperDownload.aspx?DOI=10.4236\u002Ffns.2015.64041",{"VOID":2040},"10.1007\u002Fs40475-017-0115-5","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs40475-017-0115-5",[2043],{"id":2044,"sortIndex":32,"researcher":28,"roles":2045,"affiliations":2046,"properties":2055,"displayName":2057,"givenName":28,"familyName":28},"41ab59b4-ec26-463a-8983-f9b26312e322",[968],[2047],{"id":2048,"sortIndex":32,"affiliation":2049,"properties":28},"e364c574-cd87-497c-99db-f18ebae95db0",{"id":2048,"createTime":28,"updateTime":28,"relativeEntities":2050,"slug":28,"properties":2051,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2054,"statistic":28},[],{"title":2052},{"VI":2053},"School of Nutrition, Universidad Francisco Marroquín, Guatemala, Guatemala",[],{"title":2056},{"VI":2057},"Jorge T. Rodríguez",{"url":2041,"publisher":2059,"properties":2104},{"id":868,"createTime":869,"updateTime":870,"relativeEntities":2060,"slug":872,"properties":2061,"entityType":25,"verifyStatus":880,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":32,"subjectFields":2064,"manageAffiliations":2073,"indexDatabases":2084,"url":28,"thumbnailPath":28,"statistic":2099,"gsStatistic":28,"type":55,"analyzePriority":28},[],{"issn":2062,"title":2063},{"VOID":875},{"EN":877},[2065,2069],{"id":883,"createTime":28,"updateTime":28,"relativeEntities":2066,"label":2067,"description":2068,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":886},{},{"id":889,"createTime":28,"updateTime":28,"relativeEntities":2070,"label":2071,"description":2072,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":892},{},[2074,2079],{"id":896,"createTime":28,"updateTime":28,"relativeEntities":2075,"slug":28,"properties":2076,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2078,"statistic":28},[],{"title":2077},{"EN":900},[902],{"id":904,"createTime":28,"updateTime":28,"relativeEntities":2080,"slug":28,"properties":2081,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2083,"statistic":28},[],{"title":2082},{"EN":908},[],[2085,2092],{"id":912,"indexDatabase":2086,"url":918,"indexYears":28,"academicFieldIds":2091,"indexDatabaseRanking":28},{"id":803,"createTime":28,"updateTime":28,"relativeEntities":2087,"label":2088,"description":2089,"key":810,"publicationTags":2090,"standard":28},[],{"EN":806,"VI":806},{"EN":808,"VI":809},[812,813],[920,921,922],{"id":924,"indexDatabase":2093,"url":930,"indexYears":931,"academicFieldIds":2098,"indexDatabaseRanking":935},{"id":775,"createTime":28,"updateTime":28,"relativeEntities":2094,"label":2095,"description":2096,"key":781,"publicationTags":2097,"standard":28},[],{"EN":778,"VI":778},{"EN":778,"VI":780},[783],[933,934],{"impactFactor":32,"impactFactorByYear":2100,"i10Index":32,"i10IndexLast5Year":32,"totalPublication":218,"totalPublicationByYear":2101,"totalCitation":32,"totalCitationByYear":2102,"totalCitationPerPublication":32,"totalCitationPerPublicationByYear":2103,"hindexLast5Year":32,"hindex":32},{},{"2013":42,"2014":146,"2015":205,"2016":199,"2017":130,"2018":128,"2019":126,"2020":145,"2021":128,"2022":127,"2023":127,"2024":40},{},{},{"pages":2105,"volume":2107},{"VOID":2106},"153-157",{"VOID":1134},"2017-07-10",[935,812],{"id":2111,"createTime":2112,"updateTime":2113,"relativeEntities":2114,"slug":2115,"properties":2116,"entityType":960,"verifyStatus":26,"verifyTime":2129,"verifyNote":962,"languages":28,"translateLanguages":2130,"viewCount":40,"primaryUrl":2131,"fullTextUrl":28,"authors":2132,"publicationType":1083,"publisherRelationship":2179,"citationCount":28,"citationInfo":28,"publishDate":2230,"publishYear":2231,"citationAnalyzeStatus":880,"lastCitationAnalyze":28,"indexDatabases":2232,"openAccess":28,"references":28,"isForceReanalyzing":1138},"108ea313-6787-41c4-9c4d-2a641c08b179","2024-01-05T13:04:43.310+00:00","2025-01-31T04:45:34.176+00:00",[],"Host-Cell-Factors-Involved-in-Filovirus-Infection",{"abstract":2117,"title":2120,"keywords":2123,"references":2125,"doi":2127},{"VI":2118,"EN":2119},"Các virus filovirus (virus Ebola và virus Marburg) gây ra sốt xuất huyết nghiêm trọng ở người và động vật linh trưởng không phải người với tỷ lệ tử vong cao đến 90%. Dịch bệnh virus Ebola gần đây ở các nước Tây Phi đã nhấn mạnh sự cần thiết cấp bách về các can thiệp phòng ngừa và điều trị hiệu quả cho căn bệnh truyền nhiễm chết người này. Tuy nhiên, hiện tại không có các biện pháp phòng ngừa hay điều trị được phê duyệt cho các bệnh do virus filovirus. Các nghiên cứu gần đây đã tiết lộ các cơ chế phân tử nền tảng cho chu trình sống của virus filovirus, bao gồm quá trình xâm nhập tế bào, thoát ra và thoát khỏi phản ứng miễn dịch của chủ thể, cho thấy khả năng phát triển các loại thuốc pan-filovirus hiệu quả.","Filoviruses (ebolaviruses and marburgviruses) cause severe hemorrhagic fever in humans and nonhuman primates with high mortality rates of up to 90 %. The latest epidemic of Ebola virus disease in Western African countries has underscored the urgent need for effective prophylactic and therapeutic interventions for this deadly infectious disease. However, neither approved prophylactics nor therapeutics are currently available for filovirus diseases. Recent studies have been unveiling the molecular mechanisms underlying the filovirus lifecycle, including cellular entry, egress, and the evasion from host immunity, suggesting possibilities to develop effective pan-filovirus drugs.",{"EN":2121,"VI":2122},"Host Cell Factors Involved in Filovirus Infection","Các yếu tố của tế bào chủ liên quan đến nhiễm virus filovirus",{"VI":2124},"virus filovirus, sốt xuất huyết, virus Ebola, virus Marburg, cơ chế phân tử, điều trị, can thiệp phòng ngừa.",{"VOID":2126},"Kuhn JH, Bào Y, Bavari S, Becker S, et al. Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA. Arch Virol. 2014;159(5):1229–37.\nNegredo A, Palacios G, Vázquez-Morón S, et al. Discovery of an ebolavirus-like filovirus in europe. PLoS Pathog. 2011;7(10):e1002304.\nSanchez A, Yang ZY, Xu L, et al. 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This study demonstrated that non-neutralizing monoclonal antibodies against marburgvirus GP reduced the budding and release of progeny viruses from infected cells.\nCárdenas WB, Loo YM, Gale Jr M, et al. Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha\u002Fbeta interferon production induced by RIG-I signaling. J Virol. 2006;80(11):5168–78.\nLeung DW, Prins KC, Borek DM, et al. Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35. Nat Struct Mol Biol. 2010;17(2):165–72.\nBasler CF, Wang X, Mühlberger E, et al. The Ebola virus VP35 protein functions as a type I IFN antagonist. Proc Natl Acad Sci U S A. 2000;97(22):12289–94.\nBasler CF, Mikulasova A, Martinez-Sobrido L, et al. The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3. J Virol. 2003;77(14):7945–56.\nPrins KC, Cárdenas WB, Basler CF. Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1. J Virol. 2009;83(7):3069–77.\nChang TH, Kubota T, Matsuoka M, et al. Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery. PLoS Pathog. 2009;5(6):e1000493.\nLuthra P, Ramanan P, Mire CE, et al. Mutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome. Cell Host Microbe. 2013;14(1):74–84. This study shows that ebolavirus VP35 interacts with PACT and inhibits PACT-mediated RIG-I activation, and that the PACT-VP35 interaction impairs polymerase complex formation, thereby diminishing viral RNA synthesis.\nHaasnoot J, de Vries W, Geutjes EJ, et al. The Ebola virus VP35 protein is a suppressor of RNA silencing. PLoS Pathog. 2007;3(6):e86.\nFabozzi G, Nabel CS, Dolan MA, Sullivan NJ. Ebolavirus proteins suppress the effects of small interfering RNA by direct interaction with the mammalian RNA interference pathway. J Virol. 2011;85(6):2512–23.\nFeng Z, Cerveny M, Yan Z, He B. The VP35 protein of Ebola virus inhibits the antiviral effect mediated by double-stranded RNA-dependent protein kinase PKR. J Virol. 2007;81(1):182–92.\nReid SP, Leung LW, Hartman AL, et al. Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulation. J Virol. 2006;80(11):5156–67.\nReid SP, Valmas C, Martinez O, Sanchez FM, Basler CF. Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1. J Virol. 2007;81(24):13469–77.\nMateo M, Reid SP, Leung LW, Basler CF, Volchkov VE. Ebolavirus VP24 binding to karyopherins is required for inhibition of interferon signaling. J Virol. 2010;84(2):1169–75.\nZhang AP, Bornholdt ZA, Liu T, et al. The ebola virus interferon antagonist VP24 directly binds STAT1 and has a novel, pyramidal fold. PLoS Pathog. 2012;8(2):e1002550. This is the first report showing the crystal structure of ebolavirus VP24, and also demonstrates that ebolavirus VP24 directly binds to STAT1.\nValmas C, Grosch MN, Schümann M, et al. Marburg virus evades interferon responses by a mechanism distinct from ebola virus. PLoS Pathog. 2010;6(1):e1000721.\nVolchkov VE, Chepurnov AA, Volchkova VA, Ternovoj VA, Klenk HD. Molecular characterization of guinea pig-adapted variants of Ebola virus. Virology. 2000;277(1):147–55.\nEbihara H, Takada A, Kobasa D, et al. Molecular determinants of Ebola virus virulence in mice. PLoS Pathog. 2006;2(7):e73.\nLofts LL, Ibrahim MS, Negley DL, Hevey MC, Schmaljohn AL. Genomic differences between guinea pig lethal and nonlethal Marburg virus variants. J Infect Dis. 2007;196 Suppl 2:S305–12.\nLofts LL, Wells JB, Bavari S, Warfield KL. Key genomic changes necessary for an in vivo lethal mouse marburgvirus variant selection process. J Virol. 2011;85(8):3905–17.\nEdwards MR, Johnson B, Mire CE, et al. The Marburg virus VP24 protein interacts with Keap1 to activate the cytoprotective antioxidant response pathway. Cell Rep. 2014;6(6):1017–25.\nPage A, Volchkova VA, Reid SP, et al. Marburgvirus hijacks nrf2-dependent pathway by targeting nrf2-negative regulator keap1. Cell Rep. 2014;6(6):1026–36.\nYasuda J. Ebolavirus replication and tetherin\u002FBST-2. Front Microbiol. 2012;3:111.\nJouvenet N, Neil SJ, Zhadina M, et al. Broad-spectrum inhibition of retroviral and filoviral particle release by tetherin. J Virol. 2009;83(4):1837–44.\nKaletsky RL, Francica JR, Agrawal-Gamse C, Bates P. Tetherin-mediated restriction of filovirus budding is antagonized by the Ebola glycoprotein. Proc Natl Acad Sci U S A. 2009;106(8):2886–91.\nRadoshitzky SR, Dong L, Chi X, et al. Infectious Lassa virus, but not filoviruses, is restricted by BST-2\u002Ftetherin. J Virol. 2010;84(20):10569–80.\nGnirß K, Fiedler M, Krämer-Kühl A, et al. Analysis of determinants in filovirus glycoproteins required for tetherin antagonism. Viruses. 2014;6(4):1654–71.\nFrancica JR, Varela-Rohena A, Medvec A, et al. Steric shielding of surface epitopes and impaired immune recognition induced by the ebola virus glycoprotein. PLoS Pathog. 2010;6(9):e1001098.\nNoyori O, Nakayama E, Maruyama J, Yoshida R, Takada A. Suppression of Fas-mediated apoptosis via steric shielding by filovirus glycoproteins. Biochem Biophys Res Commun. 2013;441(4):994–8.\nNoyori O, Matsuno K, Kajihara M, et al. Differential potential for envelope glycoprotein-mediated steric shielding of host cell surface proteins among filoviruses. Virology. 2013;446(1–2):152–61.\nIto H, Watanabe S, Takada A, Kawaoka Y. Ebola virus glycoprotein: proteolytic processing, acylation, cell tropism, and detection of neutralizing antibodies. J Virol. 2001;75(3):1576–80.\nMohan GS, Li W, Ye L, Compans RW, Yang C. Antigenic subversion: a novel mechanism of host immune evasion by Ebola virus. PLoS Pathog. 2012;8(12):e1003065.",{"VOID":2128},"10.1007\u002Fs40475-015-0039-x","2025-01-16T04:43:58.851+00:00",[30],"https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs40475-015-0039-x",[2133,2148],{"id":2134,"sortIndex":32,"researcher":28,"roles":2135,"affiliations":2136,"properties":2145,"displayName":2147,"givenName":28,"familyName":28},"1b944b5d-900b-4622-9f9e-06fd025c07d8",[968],[2137],{"id":2138,"sortIndex":32,"affiliation":2139,"properties":28},"256c8d60-1727-4645-9c3c-5e2863df39d9",{"id":2138,"createTime":28,"updateTime":28,"relativeEntities":2140,"slug":28,"properties":2141,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2144,"statistic":28},[],{"title":2142},{"VI":2143},"Division of Global Epidemiology, Hokkaido University Research Center for Zoonosis Control, Sapporo, Japan",[],{"title":2146},{"VI":2147},"Masahiro Kajihara",{"id":2149,"sortIndex":40,"researcher":28,"roles":2150,"affiliations":2151,"properties":2176,"displayName":2178,"givenName":28,"familyName":28},"f2935699-8dfd-43e2-bd50-e9a576be61fc",[968],[2152,2158,2167],{"id":2138,"sortIndex":32,"affiliation":2153,"properties":28},{"id":2138,"createTime":28,"updateTime":28,"relativeEntities":2154,"slug":28,"properties":2155,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2157,"statistic":28},[],{"title":2156},{"VI":2143},[],{"id":2159,"sortIndex":40,"affiliation":2160,"properties":2166},"8a1fb824-0ad2-4428-b56f-44ed3283ca8a",{"id":2159,"createTime":28,"updateTime":28,"relativeEntities":2161,"slug":28,"properties":2162,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2165,"statistic":28},[],{"title":2163},{"VI":2164},"Global Institution for Collaborative Research and Education, Hokkaido University, Sapporo, Japan",[],{},{"id":2168,"sortIndex":123,"affiliation":2169,"properties":2175},"f937e79d-d7cb-4816-9d94-1f2f604b2114",{"id":2168,"createTime":28,"updateTime":28,"relativeEntities":2170,"slug":28,"properties":2171,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2174,"statistic":28},[],{"title":2172},{"VI":2173},"School of Veterinary Medicine, The University of Zambia, Lusaka, Zambia",[],{},{"title":2177},{"VI":2178},"Ayato Takada",{"url":2131,"publisher":2180,"properties":2225},{"id":868,"createTime":869,"updateTime":870,"relativeEntities":2181,"slug":872,"properties":2182,"entityType":25,"verifyStatus":880,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":32,"subjectFields":2185,"manageAffiliations":2194,"indexDatabases":2205,"url":28,"thumbnailPath":28,"statistic":2220,"gsStatistic":28,"type":55,"analyzePriority":28},[],{"issn":2183,"title":2184},{"VOID":875},{"EN":877},[2186,2190],{"id":883,"createTime":28,"updateTime":28,"relativeEntities":2187,"label":2188,"description":2189,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":886},{},{"id":889,"createTime":28,"updateTime":28,"relativeEntities":2191,"label":2192,"description":2193,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":892},{},[2195,2200],{"id":896,"createTime":28,"updateTime":28,"relativeEntities":2196,"slug":28,"properties":2197,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2199,"statistic":28},[],{"title":2198},{"EN":900},[902],{"id":904,"createTime":28,"updateTime":28,"relativeEntities":2201,"slug":28,"properties":2202,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2204,"statistic":28},[],{"title":2203},{"EN":908},[],[2206,2213],{"id":912,"indexDatabase":2207,"url":918,"indexYears":28,"academicFieldIds":2212,"indexDatabaseRanking":28},{"id":803,"createTime":28,"updateTime":28,"relativeEntities":2208,"label":2209,"description":2210,"key":810,"publicationTags":2211,"standard":28},[],{"EN":806,"VI":806},{"EN":808,"VI":809},[812,813],[920,921,922],{"id":924,"indexDatabase":2214,"url":930,"indexYears":931,"academicFieldIds":2219,"indexDatabaseRanking":935},{"id":775,"createTime":28,"updateTime":28,"relativeEntities":2215,"label":2216,"description":2217,"key":781,"publicationTags":2218,"standard":28},[],{"EN":778,"VI":778},{"EN":778,"VI":780},[783],[933,934],{"impactFactor":32,"impactFactorByYear":2221,"i10Index":32,"i10IndexLast5Year":32,"totalPublication":218,"totalPublicationByYear":2222,"totalCitation":32,"totalCitationByYear":2223,"totalCitationPerPublication":32,"totalCitationPerPublicationByYear":2224,"hindexLast5Year":32,"hindex":32},{},{"2013":42,"2014":146,"2015":205,"2016":199,"2017":130,"2018":128,"2019":126,"2020":145,"2021":128,"2022":127,"2023":127,"2024":40},{},{},{"pages":2226,"volume":2228},{"VOID":2227},"30-40",{"VOID":2229},"2","2015-02-03",2015,[935,812],{"id":2234,"createTime":2235,"updateTime":2236,"relativeEntities":2237,"slug":2238,"properties":2239,"entityType":960,"verifyStatus":26,"verifyTime":2248,"verifyNote":962,"languages":28,"translateLanguages":28,"viewCount":32,"primaryUrl":2249,"fullTextUrl":28,"authors":2250,"publicationType":1083,"publisherRelationship":2320,"citationCount":28,"citationInfo":28,"publishDate":2370,"publishYear":1786,"citationAnalyzeStatus":880,"lastCitationAnalyze":28,"indexDatabases":2371,"openAccess":28,"references":28,"isForceReanalyzing":1138},"119b409d-e503-46ce-9c3b-c3f271ed322e","2024-01-16T19:48:22.106+00:00","2025-01-16T03:38:18.880+00:00",[],"Diagnostic-Aspects-of-Paracoccidioidomycosis",{"abstract":2240,"title":2242,"references":2244,"doi":2246},{"EN":2241},"The gold standard for the diagnosis of paracoccidioidomycosis is direct examination and culture; however, serologic, histopathologic, and molecular approaches have been recently adopted for the diagnosis of this mycosis. Few molecular methods have been applied to the diagnosis of paracoccidioidomycosis to detect Paracoccidioides spp. DNA from clinical specimens, and to identify the same fungi in culture. In this review, we focus on the current diagnosis of the paracoccidioidomycosis, and discuss the current molecular tools applied to the diagnosis and identification of the Paracoccidioides complex species.",{"EN":2243},"Diagnostic Aspects of Paracoccidioidomycosis",{"VOID":2245},"San-Blas G, Nino-Vega G, Iturriaga T. Paracoccidioides brasiliensis and paracoccidioidomycosis: molecular approaches to morphogenesis, diagnosis, epidemiology, taxonomy and genetics. Med Mycol. 2002;40:225–42.\nMatute DR, McEwen JG, Puccia R, et al. Cryptic speciation and recombination in the fungus Paracoccidioides brasiliensis as revealed by gene genealogies. Mol Biol Evol. 2006;23:65–73.\nCarrero LL, Niño-Vega G, Teixeira MM, et al. New Paracoccidioides brasiliensis isolate reveals unexpected genomic variability in this human pathogen. Fungal Genet Biol. 2008;45:605–12.\nTeixeira MM, Theodoro RC, Carvalho MJ, et al. Phylogenetic analysis reveals a high level of speciation in the Paracoccidioides genus. Mol Phylogenet Evol. 2009;52:273–83. A new species, Paracoccidioides lutzii, is proposed based on phylogenetic analysis.\nColombo AL, Tobón A, Restrepo A, et al. Epidemiology of endemic systemic fungal infections in Latin America. Med Mycol. 2011;49:785–98.\nBuitrago MJ, Cuenca-Estrella M. Epidemiologia actual y diagnóstico de laboratório de las micosis endêmicas em España. Enferm Infecc Microbiol Clin. 2012;30:407–13.\nMartinez R. Paracoccidioidomycosis: the dimension of the problem of a neglected disease. Re Soc Bras Med Trop. 2010;43:480.\nRamos-e-Silva M, Saraiva LES. Paracoccidioidomycosis. Dermatol Clin. 2008;26:257–69.\nMoreto TC, Marques MEA, Oliveira MLSC, et al. Accuracy of routine diagnostic tests used in paracoccidioidomycosis patients at a university hospital. Trans R Trop Med Hyg. 2011;105:473–8.\nMarques SA. Paracoccidioidomycosis. Clin Dermatol. 2012;30:610–5.\nQueiroz-Telles F, Escussiato DL. Pulmonary paracoccidioidomycosis. Semin Respir Crit Care Med. 2011;32:764–74.\nWanke B, Aide MA. Paracoccidioidomycosis. J Bras Pneumol. 2009;35:1245–9.\nMoraes AML, Almeida-Paes R, Holanda VL. Micologia. In: Molinaro E, Caputo L, Amendoeira R, editors. Conceitos e métodos para formação de profissionais em laboratórios de saúde. Assis: Triunfal Gráfica e Editora; 2010. p. 399–496. ISBN 978-85-98768-41-0.\nLarone DH. Medically important fungi: a guide to identification. 4th ed. Washington, DC: ASM Press; 2002. ISBN 1-55581-172-8.\nBonifaz A, Vázquez-González D, Perusquía-Ortiz AM. Endemic systemic mycoses: coccidioidomycosis, histoplasmosis, paracoccidioidomycosis and blastomycosis. 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A proposal for a microdilution test for P. brasiliensis susceptibility testing against important drugs used in the treatment of paracoccidioidomycosis is presented and a high percentage of susceptible isolates were found under the several experimental conditions used.\nMarques-da-Silva SH, Colombo AL, Blotta MHSL, et al. Diagnosis of paracoccidioidomycosis by detection of antigen and antibody in bronchoalveolar lavage fluids. Clin Vac Immunol. 2006;13:1363–6.\nSilveira-Gomes F, Sarmento DN, Pinto TM, et al. Development and evaluation of latex agglutination test for the serodiagnosis of paracoccidioidomycosis. Clin Vac Immunol. 2011;18:604–8.\nCaldini CP, Xander P, Kioshima ES, et al. Synthetic peptides mimic gp75 from Paracoccidioides brasiliensis in the diagnosis of paracoccidioidomycosis. Mycopathologia. 2012;174:1–10. P2 peptide that represents a mimotope of gp75 is a potential tool for the immunodiagnosis of paracoccidioidomycosis.\nMoses A. Fixação de complemento na blastomicose. Mem Inst Oswaldo Cruz. 1916;8:68–70.\nCamargo ZP. Serology of paracoccidioidomycosis. Mycopathologia. 2008;165:289–302.\nFernandes VC, Coitinho JB, Veloso JMR, et al. Combined use of Paracoccidioides brasiliensis rPb27 and rPb40 antigens in an enzyme-linked immunosorbent assay for immunodiagnosis of paracoccidioidomycosis. J Immunol Methods. 2011;367:78–84. The use of combined recombinant antigens in an ELISA provided an excellent assay with high sensitivity and specificity for the immunodiagnosis of paracoccidioidomycosis.\nBelissimo-Rodrigues F, Vitali LH, Martinez R. Serological diagnosis of paracoccidioidomycosis in HIV-coinfected patients. Mem Inst Oswaldo Cruz. 2010;105:904–7.\nBelissimo-Rodrigues F, Machado AA, Martinez R. Paracoccidioidomycosis epidemiological features of a 1,000-cases series from a hyperendemic area of Southeast of Brazil. Am J Trop Med Hyg. 2011;85:546–50.\nPerenha-Viana MCZ, Gonzales IAA, Brockelt SR, et al. Serological diagnosis of paracoccidioidomycosis through a western blot technique. Clin Vac Immunol. 2012;19:616–9.\nMachado GC, Moris DV, Arantes TD, et al. Cryptic species of Paracoccidioides brasiliensis: impact on paracoccidioidomycosis immunodiagnosis. Mem Inst Oswaldo Cruz. 2013;108:637–43. The speciation within Paracoccidioides brasiliensisis is important for the serological diagnosis of paracoccidioidomycosis.\nMendes-Giannini MJS, Bueno JP, Shikanai-Yassuda MA, et al. Antibody response to 43 kDa glycoprotein of Paracoccidioides brasiliensis as a marker for the evaluation of patients under treatment. Am J Trop Med Hyg. 1990;43:200–6.\nBlotta MHSL, Camargo ZP. Immunological response to cell-free antigens of Paracoccidioides brasiliensisis: relationship with clinical forms of paracoccidioidomycosis. J Clin Microbiol. 1993;31:671–6.\nDíez S, Gómez BL, Restrepo A, et al. Paracoccidioides brasiliensis 87-kilodalton antigen, a heat shock protein useful in diagnosis: characterization, purification, and detection in biopsy material via immunohistochemistry. J Clin Microbiol. 2002;40:359–65.\nCisalpino PS, Puccia R, Yamauchi LM, et al. Cloning, characterization and epitope expression of the major diagnostic antigen of Paracoccidioides brasiliensisis. J Biol Chem. 1996;271:4553–60.\nMcEwen JG, Ortiz BL, Garcia AM, et al. Molecular cloning, nucleotide sequencing, and characterization of a 27 kDa antigenic protein from Paracoccidioides brasiliensisis. Fun Gen Biol. 1996;20:125–31.\nOrtiz BL, Garcia AM, Restrepo A, et al. Immunological characterization of a recombinant 27-kilodanton antigenic protein from Paracoccidioides brasiliensisis. Clin Diagn Lab Immunol. 1996;3:239241.\nOrtiz BL, Díez S, Urán ME, Rivas JM, et al. Use of the 27-kilodalton recombinant protein from Paracoccidioides brasiliensis in serodiagnosis of paracoccidioidomycosis. Clin Diagn Lab Immunol. 1998;5:826–30.\nSantos LS, Fernandes VC, Cruz SG, et al. Profile of total IgG, IgG1, IgG2, IgG3 and IgG4 levels in sera of patients with paracoccidioidomycosis: treatment follow-up using Mexo and rPb27 as antigen in an ELISA. Mem Inst Oswaldo Cruz. 2012;107:1–10.\nCunha DA, Zancopé-Oliveira RM, Sueli M, Felipe S, et al. Heterologous expression, purification, and immunological reactivity of a recombinant HSP60 from Paracoccidioides brasiliensis. Clin Diagn Lab Immunol. 2002;9:374–7.\nBisio LC, Silva SP, Pereira IS, et al. A new Paracoccidioides brasiliensis 70-kDa heat shock protein reacts with sera from paracoccidioidomycosis patients. Med Mycol. 2005;43:495–503.\nDíez S, Gómez BL, McEwen JG, et al. Combined use of Paracoccidioides brasiliensis recombinant 27-kilodalton and purified 87-kilodalton antigens in an enzyme-linked immunosorbent assay for serodiagnosis of paracoccidioidomycosis. J Clin Microbiol. 2003;41:1536–42.\nHamilton. Serodiagnosis of histoplasmosis, paracoccidioidomycosis, and penicilliosis marneffei: current status and future trends. Med Mycol. 1998;1998(36):351–64.\nChen SCA, Halliday CL, Meyer W. A review of nucleic acid-based diagnostic tests for systemic mycoses with an emphasis on polymerase chain reaction-based assays. Med Mycol. 2002;40:333–57.\nSandhu GS, Aleff RA, Kline BC, Lacaz CS. Molecular detection and identification of Paracoccidioides brasiliensis. J Clin Microbiol. 1997;35:1894–6.\nMotoyama AB, Venancio EJ, Brandão GO, et al. Molecular identification of Paracoccidioides brasiliensis by PCR amplification of ribosomal DNA. J Clin Microbiol. 2000;38:3106–9.\nBuitrago MJ, Merino P, Puente S, et al. Utility of real-time PCR for the detection of Paracoccidioides brasiliensis DNA in the diagnosis of imported paracoccidioidomycosis. Med Mycol. 2009;47:879–82.\nBuitrago MJ, Bernal-Martinez L, Castelli MV, et al. Histoplasmosis and paracoccidioidomycosis in a non-endemic area: a review of cases and diagnosis. J Travel Med. 2011;18:26–33.\nDias L, Carvalho LF, Romano CC. Application of PCR in serum samples for diagnosis of paracoccidioidomycosis in the Southern Bahia-Brazil. PLoS Neg Trop Dis. 2012;6:e1909.\nKoishi AC, Vituri DF, Donizio Filho PS, et al. A semi-nested PCR assay for molecular detection of Paracoccidioides brasiliensis in tissue samples. Rev Soc Bras Med Trop. 2010;43:728–30.\nArantes TD, Theodoro RC, Macoris SAG, Bagagli E. Detection of Paracoccidioides spp. in environmental aerosol samples. Med Mycol. 2013;51:83–92.\nGomes GM, Cisalpino PS, Taborda CP, et al. PCR for diagnosis of paracoccidiodomycosis. J Clin Microbiol. 2000;38:3478–80.\nBialek R, Ibricevic A, Aepinus C, et al. Detection of Paracoccidioides brasiliensis in tissue samples by a nested PCR assay. J Clin Microbiol. 2000;38:2940–2.\nSano A, Yokoyama K, Tamura M, et al. Detection of gp43 and ITS1-5.8S-ITS2 ribosomal RNA genes for Paracoccidioides brasiliensis in paraffin-embedded tissue. Nihon Ishinkin Gakkai Zasshi. 2001;42:23–7.\nCharbel CE, Levi JE, Martins JE. Evaluation of polymerase chain reaction for the detection of Paracoccidioides brasiliensis DNA on serum samples from patients with paracoccidioidomycosis. Mem Inst Oswaldo Cruz. 2006;101:229–2.\nRicci G, Da Silva ID, Borra RC. Detection of Paracoccidioides brasiliensis by PCR in biopsies from patients with paracoccidioidomycosis: correlation with the histopathological pattern. Pathologica. 2007;99:41–5.\nSemighini CP, Camargo ZP, Puccia R, Goldman MHS, Goldman GH. Molecular identification of Paracoccidioides brasiliensis by 5′ nuclease assay. Diagn Microbiol Infect Dis. 2002;44:383–6.\nBorba CM, Vinhas EAL, Lopes-Bezerra LM, Lucena-Silva N. Morphological, biochemical and molecular approaches for comparing typical and atypical Paracoccidioides brasiliensis strains. Antonie van Leeuwenhoek. 2005;88:257–66.\nCorreia J, Borba CM, Reis B, et al. The ceja-1 sequence as a potential new molecular marker for Paracoccidioides brasiliensis infection. Mycoses. 2009;53:130–7.\nNino-Vega GA, Calcagno AM, San-Blas G, et al. RFLP analysis reveals marked geographical isolation between strains of Paracoccidioides brasiliensis. Med Mycol. 2000;38:437–41.\nMontoya AE, Alvarez AL, Moreno MN, Restrepo A, McEwen JG. Electrophoretic karyotype of environmental isolates of Paracoccidioides brasiliensis. Med Mycol. 1999;37:229–22.\nMolinari-Madlum EE, Felipe MS, Soares CMA. Virulence of Paracoccidioides brasiliensis isolates can be correlated to groups defined by random amplified polymorphic DNA analysis. Med Mycol. 1999;37:269–76.\nTotti DO, Romanha AJ, Grisard EC, Simpson AJ, Koury MC. Random amplified polymorphic DNA (RAPD) analysis of Paracoccidioides brasiliensis isolates. Rev Latinoam Microbiol. 1999;41:139–43.\nRicci G, Zelck U, Mota F, et al. Genotyping of Paracoccidioides brasiliensis directly from paraffin embedded tissue. Med Mycol. 2008;46:31–4.\nMatute DR, Sepulveda VE, Quesada LM, et al. Microsatellite analysis of three phylogenetic species of Paracoccidioides brasiliensis. J Clin Microbiol. 2006;44:2253–7.\nTheodoro RC, Bagagli E, Oliveira C. Phylogenetic analysis of PRP8 intein in Paracoccidioides brasiliensis species complex. Fungal Genet Biol. 2008;45:1284–91.\nTheodoro RC, Teixeira MM, Felipe MSS, et al. Genus Paracoccidioides: species recognition and biogeographic aspects. PLoS One. 2012;7:e37694. This work presents a theory on how this fungus diverged in South America, thus elucidating some evolutionary aspects of this genus.",{"VOID":2247},"10.1007\u002Fs40475-014-0022-y","2025-01-16T03:38:18.879+00:00","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs40475-014-0022-y",[2251,2266,2279,2292,2307],{"id":2252,"sortIndex":32,"researcher":28,"roles":2253,"affiliations":2254,"properties":2263,"displayName":2265,"givenName":28,"familyName":28},"3ced5690-c93f-41e4-aa83-da765e2ee94c",[968],[2255],{"id":2256,"sortIndex":32,"affiliation":2257,"properties":28},"436c5690-eac8-47c7-b11b-2ef71f1a9153",{"id":2256,"createTime":28,"updateTime":28,"relativeEntities":2258,"slug":28,"properties":2259,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2262,"statistic":28},[],{"title":2260},{"VI":2261},"Setor de Imunodiagnóstico do Laboratório de Micologia do Instituto de Pesquisa Clínica 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purpose is to report and describe four cases of Echinococcus vogeli hydatidosis in Colombia. Four E. vogeli polycystic hydatidosis cases are presented, two males and two females, aged 18 to 68 years old, from four separate forest Colombian regions. The initial diagnosis of the cystic disease was radiologically obtained, and parasite presence was confirmed through study of the histological material. The locations of the cysts were hepatic in three cases and mesenteric in the other. Surgical resection was performed on all four patients, complemented by albendazole in two of them. Review of clinical findings, diagnoses, and treatment for E. vogeli hydatidosis.",{"EN":2382},"Report of Four Cases of Neotropical Polycystic Equinococcosis Caused by Echinococcus vogeli in Colombia",{"VOID":2384},"Ecker J, Desplazes P. Biological, epidemiological, and clinical aspects of echinococcosis, a zoonosis of increasing concern. Clin Microbiol Rev. 2004;17:107–35.\nRausch RL, D’Alessandro A, Rausch VR. Characteristics of the larval Echinococcus vogeli Rausch and Berstein, in the natural intermediate host, the paca, Cuniculus paca L. (Rodentia: Dasyproctidae). Am J Trop Med Hyg. 1972;30:1043–52.\nD’Alessandro A, Rausch RL. New aspects of neotropical polycystic (Echinococcus vogeli) and unicystic (Echinococcus oligarthrus), echinococcosis. Clin Microbiol Rev. 2008;21:380–401.\nGenzini T, de Siqueira NG, Noujaiim HM, dos Santos RG, Yamashita ET, Trevizol AP, et al. Liver transplantation polycystic echinococcosis caused by Echinococcus vogeli: a case report. Rev Soc Bras Med Trop. 2013;46:119–20.\nThatcher VC. Neotropical echinococcosis in Colombia. Ann Trop Med Parasitol. 1972;665:99–105.\nD’Alessandro A, Rausch RL, Cuello C, Aristizabal N. Echinococcus vogeli in man, with a review of polycystic hydatid disease in Colombia and neighboring countries. Am J Trop Med Hyg. 1979;28:303–17.\nD’Alessandro A. Polycystic echinococcosis in tropical America: Echinococcus vogeli and E. oligarthus. Acta Trop. 1997;67:43–65.\nEl-Tahir MI, Omojola MF, Malatani T, Papageorgoou A, Vassilakis JS. Hydatid disease of the liver: evaluation of ultrasound and computed tomography. Br J Radiol. 1992;65:390–2.\nMeneghelli UG, Martinelli ALC, Llorach-Velludo MAS. Cistos de Echinococcus vogeli figado de paca (Cuniculu paca) originaria de estado do Acre, Brasil. Rev Soc Brasil Med Trop. 1990;23:153–5.\nMeneghelli UG, Martinelli ALC, Belluci AD, Villanova MG, Llorach-Velludo MAS, Magro JE. Polycystic hydatid disease (Echinococcus vogeli).: treatment with albendazole. 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