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Journal of Medicine and Pharmacy","Tạp chí Y Dược học Cần Thơ",{"EN":487,"VI":488},"\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">04\u002F10\u002F2015 Ministry of Information and Communications allowed Can Tho journal of medicine and pharmacy to operate (102 \u002FGP-BTTTT)\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">07\u002F16\u002F2015 Can Tho journal of medicine and pharmacy is internationally recognized: ISSN 2354-1210\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">In 2016, The journal has been included in the list of medical science journals by The State Council for professorship which is awarded a work score of 0-0.5 points for a published article.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Can Tho Journal of Medicine and Pharmacy welcome original works that haven’t been submitted or published in other medical journals. Posts must contain content related to one of the journal’s categories.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The content published\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The journal is divided into 3 categories:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Scientific research article: are valuable scientific works, which have been researched and accepted.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Overview of medicine, biology and pharmacy: serving the objective of continuing training in the fields of medicine, biology and pharmacy; to systematize classical and modern knowledge.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Update information on new knowledge about medicine, biology, pharmacy in the country and in the world.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Scope\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Publication and introduction of scientific research in the fields:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Medicine (internal medicine, surgery, pediatrics, obstetrics and gynecology, odonto-stomatology, laboratory, oncology, traditional medicine, nursing).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Biology (genetics, biotechnology).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Pharmacology (pharmaceutics, drug quality analysis-control, synthetic pharmaceutical chemistry, biochemistry, pharmacognosy, botany, clinical pharmacy).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- To enhance the quality of undergraduate, postgraduate education, scientifically researching and meet the necessary treatment in hospital.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Introducing the updated domestic and oversea information about science technology to promote scientific research and exchanging technology in local, other universities.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Exchanging pharmaceutical and medical information for social health developing in the Mekong Delta and Vietnam.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The object\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Postgraduate students, student of Can Tho University of Medicine and Pharmacy, scientists from schools, research institutes, hospitals, health centers, pharmaceutical companies of the Mekong Delta; other provinces and regions in Vietnam and other country.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Address\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Headquarters of Can Tho Journal of Medicine and Pharmacy, located Scientific Research and International Cooperation Office: 179 Nguyen Van Cu Street, An Khanh Ward, Ninh Kieu District, Can Tho City, Vietnam.\u003C\u002Fspan>\u003C\u002Fp>","\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Ngày 16\u002F7\u002F2015, Tạp chí Y Dược học Cần Thơ được cấp chỉ số quốc tế: ISSN 2354-1210.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 4\u002F2016, Tạp chí đã được Hội đồng Giáo sư ngành Y đưa vào danh sách các tạp chí khoa học Y học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Năm 2020 Tạp chí Y Dược học Cần Thơ đã được phê duyệt vào danh mục của các Hội đồng Giáo sư ngành Dược học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ ra 12 số\u002Fnăm, 180-200 trang\u002Fsố.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 12\u002F2022 Tạp chí Y Dược học Cần Thơ là thành viên của hệ thống Crossref và từ tháng 01\u002F2023 tạp chí thực hiện bình duyệt online kín 2 chiều nhằm tăng tính minh bạch, tin cậy của các công trình nghiên cứu khoa học và đảm bảo tốt nhất chất lượng khoa học của bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ, mục đích và phạm vi của tạp chí\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ và mục đích hoạt động của tạp chí: xuất bản nhằm mục đích phổ biến kết quả từ các đề tài nghiên cứu khoa học; giao lưu trao đổi khoa học, chia sẻ kinh nghiệm, học tập, đồng thời cập nhật thông tin khoa học mới trong các lĩnh vực y, sinh, dược học trong và ngoài nước.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phạm vi của tạp chí: Tạp chí xuất bản được chia thành 3 chuyên mục: (i) Bài báo nghiên cứu khoa học là kết quả công trình nghiên cứu khoa học có giá trị đã được triển khai nghiên cứu, (ii) Bài tổng quan y, sinh, dược học: phục vụ mục tiêu đào tạo liên tục trong lĩnh vực y, sinh, dược học; nhằm hệ thống hóa những kiến thức kinh điển và hiện đại; (iii) Thông tin cập nhật kiến thức mới về y, sinh, dược học trong nước và trên thế giới.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Chính sách truy cập mở\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ áp dụng chính sách truy cập mở đối với các bài báo đã xuất bản đến với độc giả, nhằm mở rộng cơ hội tiếp cận các kết quả nghiên cứu chất lượng cao và tăng cường trao đổi kiến thức. Tạp chí đăng tải trực tuyến (miễn phí) toàn văn các bài báo được công bố trên website của Tạp chí (https:\u002F\u002Ftapchi.ctump.edu.vn).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đạo đức xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ cam kết tuân thủ đạo đức xuất bản phù hợp với các hướng dẫn và tiêu chuẩn của the Committee on Publication Ethics (COPE), tuân thủ các nguyên tắc của COPE’s Core Practices, Best Practices Guidelines for Journal Editors và Guidelines on Good Publication Practices.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Bản thảo bài báo chỉ được chấp nhận khi được tác giả chịu trách nhiệm chính cam kết các nội dung sau: Các nội dung của bản thảo chưa được đăng tải toàn bộ hoặc một phần ở các tạp chí khác; Tất cả các tác giả đều có đóng góp một cách đáng kể vào quá trình nghiên cứu hoặc chuẩn bị bản thảo và cùng chịu trách nhiệm về các nội dung của bản thảo; Tuân thủ các biện pháp đảm bảo đạo đức nghiên cứu (ví dụ thỏa thuận đồng ý tham gia nghiên cứu).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Cam kết bảo mật\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí cam kết thực hiện và tuân thủ các quy định của luật và các văn bản hướng dẫn liên quan đến bảo mật thông tin cá nhân trên không gian mạng. Các thông tin mà người dùng (tác giả, độc giả, biên tập viên, người phản biện) nhập vào các biểu mẫu trên Hệ thống Quản lý xuất bản trực tuyến của tạp chí chỉ được sử dụng vào các mục đích đã được tuyên bố rõ ràng và sẽ không được cung cấp cho bất kỳ bên thứ ba nào khác, hay dùng vào bất kỳ mục đích nào khác.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phí gửi bài\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng bài: 1.000.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng nhanh: 1.500.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với tác giả là cán bộ viên chức thuộc Trường Đại học Y Dược Cần Thơ thì được hỗ trợ 50% lệ phí gửi đăng bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với sinh viên thực hiện đề tài nghiên cứu khoa học cấp trường được hỗ trợ 100% lệ phí đăng bài ( Tác giả gửi đính kèm “ Quyết định về việc giao tổ chức thực hiện đề tài nghiên cứu khoa học cấp Trường của sinh viên”).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Hình thức nộp lệ phí:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Tiền mặt:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Nộp trực tiếp tại Phòng Tài chính - Kế toán, Trường Đại học Y Dược Cần Thơ, số 179 Nguyễn Văn Cừ, P. An Khánh, Q. Ninh Kiều, thành phố Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Chuyển khoản:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tên Tài khoản: Trường ĐHYD Cần Thơ, Số TK: 0111000115668, tại ngân hàng Vietcombank chi nhánh Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Thời gian: Áp dụng từ ngày 01\u002F02\u002F2023.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">* Phí gửi bài không được hoàn trả khi bài viết bị từ chối hoặc tác giả xin rút bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Quy trình phản biện bài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ thực hiện quy trình phản biện kín hai chiều nghiêm ngặt. Danh tính của những người phản biện không được tiết lộ cho các tác giả và ngược lại. Quy trình thẩm định bài báo đăng gồm các bước sau:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tiếp nhận bản thảo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tác giả liên hệ gửi bản thảo đến Tạp chí qua hệ thống trực tuyến tại website: https:\u002F\u002Ftapchi.ctump.edu.vn. Hướng dẫn về cách đăng ký, gửi bài và chuẩn bị bản thảo được cung cấp trên website của Tạp chí.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sàng lọc sơ bộ\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sau khi Tòa soạn nhận được bài báo của tác giả, Ban Thư ký sẽ tiến hành kiểm tra sơ bộ bài báo (các yêu cầu về nội dung và hình thức). Những bài báo không đúng quy cách hoặc có nội dung không phù hợp hoặc vi phạm bản quyền sẽ bị từ chối (Ban Thư ký thông báo phản hồi đến tác giả trong vòng 1 tuần). Những bài báo đủ điều kiện, được Ban Thư ký tòa soạn chuyển đến Ban Biên tập có cùng chuyên môn với nội dung bài báo để đề xuất người phản biện. Thời gian kể từ khi Ban Biên tập nhận bài báo đến khi đề xuất người phản biện bài báo chậm nhất là 5 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Vòng phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký gửi bài và yêu cầu phản biện đến 02 phản biện độc lập.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Các phản biện gởi nhận xét cho Ban Thư ký. Thời gian từ khi gửi bài cho phản biện đến khi nhận ý kiến của phản biện tối đa là 20 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xử ký kết quả phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Nếu ý kiến đồng ý cho đăng và không cần chỉnh sửa, Ban Thư ký tiếp tục đăng bài theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Nếu ý kiến đồng ý đăng và cần chỉnh sửa, Ban Thư ký sẽ thông tin đến tác giả chỉnh sửa theo yêu cầu của người phản biện. Thời gian chỉnh sửa và gửi lại kéo dài không quá 2 tuần, từ khi tác giả bài báo nhận được thông tin (Quá trình này có thể lặp lại tối đa 2 lần\u002F1 bài báo). Khi có sự thống nhất, đồng ý của người phản biện; bài báo được tiếp tục đăng theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Những bài báo có chất lượng không đạt yêu cầu, cả 2 phản biện không đồng ý cho đăng sẽ bị Tòa soạn từ chối đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký tổng hợp các bản thảo đã được tác giả hoàn thiện sau thẩm định trình Ban Biên tập xem xét, Tổng Biên tập phê duyệt, quyết định bài đăng theo các tiêu chí: sự phù hợp nội dung với tôn chỉ và mục đích, thể loại bài viết (ưu tiên các bài có bài có nghiên cứu chuyên sâu, hàm lượng khoa học cao), đóng góp mới bài báo, bài báo được ưu tiên đăng trong số gần nhất của Tạp chí theo thứ tự: tính thời sự, chất lượng bài báo và thời gian gửi bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Ban Biên tập và Ban Thư ký biên tập bản thảo, chế bản, đọc rà soát lỗi. Thời gian hoàn thành từ 10-15 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Ban Thư ký có trách nhiệm thông báo cho tác giả bài báo (bằng e-mail) về tình hình phê duyệt bài báo, thời gian, số kỳ, tập xuất bản bài báo theo qui định.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">4. Danh sách bài báo theo số Tạp chí được in ấn và phát hành trong năm định kỳ được công bố chính thức trên website: https:\u002F\u002Ftapchi.ctump.edu.vn\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>",{"VOID":490},"wcQ1uqwAAAAJ","2023-05-30T08:17:21.868+00:00",[],[494],{"id":495,"createTime":28,"updateTime":28,"relativeEntities":496,"slug":28,"properties":497,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":507,"parentIds":508,"statistic":28},"6413896b-eca9-442b-a73f-182a58a0ce40",[],{"title":498,"address":501,"country":504,"abbreviation":505},{"EN":499,"VI":500},"Can Tho University of Medicine and Pharmacy","Trường Đại học Y Dược Cần Thơ",{"EN":502,"VI":503},"No 179, Nguyen Van Cu street, An Khanh ward, Ninh Kieu district, Can Tho city, Vietnam","Số 179, đường Nguyễn Văn Cừ, phường An Khánh, quận Ninh Kiều, thành phố Cần Thơ, Việt Nam",{"VOID":15},{"VOID":506},"ctump","http:\u002F\u002Fwww.ctump.edu.vn\u002F",[],[],"https:\u002F\u002Ftapchi.ctump.edu.vn\u002Findex.php\u002Fctump",{"impactFactor":32,"impactFactorByYear":512,"i10Index":32,"i10IndexLast5Year":32,"totalPublication":514,"totalPublicationByYear":515,"totalCitation":520,"totalCitationByYear":521,"totalCitationPerPublication":108,"totalCitationPerPublicationByYear":523,"hindexLast5Year":45,"hindex":45},{"2022":513,"2023":111,"2024":106},0.01,1556,{"2020":47,"2021":516,"2022":517,"2023":518,"2024":519,"2025":122},57,306,801,358,161,{"2021":146,"2022":280,"2023":522},99,{"2021":524,"2022":318,"2023":104},0.23,{"impactFactor":28,"impactFactorByYear":28,"i10Index":123,"i10IndexLast5Year":123,"totalPublication":526,"totalPublicationByYear":527,"totalCitation":526,"totalCitationByYear":528,"totalCitationPerPublication":40,"totalCitationPerPublicationByYear":531,"hindexLast5Year":49,"hindex":49},476,{"0":205,"2019":123,"2021":139,"2022":459,"2023":451,"2024":357,"2025":49,"2026":48},{"2021":42,"2022":123,"2023":161,"2024":529,"2025":360,"2026":530},136,83,{"2021":105,"2022":513,"2023":532,"2024":127,"2025":533,"2026":534},0.62,25.43,13.83,{"id":536,"createTime":537,"updateTime":382,"relativeEntities":538,"slug":539,"properties":540,"entityType":25,"verifyStatus":26,"verifyTime":28,"verifyNote":28,"languages":552,"translateLanguages":28,"viewCount":133,"subjectFields":553,"manageAffiliations":554,"indexDatabases":555,"url":556,"thumbnailPath":557,"statistic":558,"gsStatistic":594,"type":55,"analyzePriority":28},"6984a56a-db70-403b-9cc4-4013e1ceaffa","2023-05-09T06:47:40.346+00:00",[],"T%E1%BA%A1p%20ch%C3%AD%20Nghi%C3%AAn%20c%E1%BB%A9u%20n%C6%B0%E1%BB%9Bc%20ngo%C3%A0i",{"country":541,"issn":542,"title":544,"introduce":547,"gsId":550},{"VOID":15},{"VOID":543},"25252445",{"EN":545,"VI":546},"VNU Journal of Foreign Studies","Tạp chí Nghiên cứu nước ngoài",{"EN":548,"VI":549},"{\"ops\":[{\"insert\":\"\\n\\nThe \\n\"},{\"attributes\":{\"italic\":true},\"insert\":\"VNU Journal of Science\"},{\"insert\":\"\\n was established in 1985 for the publication of national and international research papers in all fields of natural sciences and technology, social sciences and humanities. 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Ma trận được lộ ra này có xu hướng bị phân hủy thủy phân chậm bởi các enzym collagenolytic nội sinh, các metalloproteinase trong ma trận (MMPs) và các cathepsin cysteine từ cơ thể. Trong bài báo này, chúng tôi tổng hợp các phát hiện gần đây cho thấy việc ức chế các enzym collagenolytic trong nước bọt hoặc trong ngà răng có thể cung cấp các phương tiện phòng ngừa chống lại sự tiến triển của sâu răng hoặc ăn mòn, tương tự như cách mà chúng đã được chứng minh là giữ được tính toàn vẹn và cải thiện độ bền của sự liên kết giữa vật liệu composite resin và ngà răng. Bài báo này cũng đưa ra luận điểm rằng ma trận hữu cơ trong ngà bị ảnh hưởng bởi sâu răng có thể không được bảo tồn nguyên vẹn như đã được xem xét trước đây. Trong ngà răng được khử khoáng một phần, các MMPs và các cathepsin cysteine có khả năng cắt đứt các đầu không xoắn của các phân tử collagen (telopeptide) có thể dẫn đến sự mất dần các khoảng trống giữa các phân tử. Điều này sẽ nghiêm trọng làm suy giảm khả năng của ma trận trong việc tái khoáng hóa nội bào, điều mà được coi là cần thiết trong việc phục hồi các tính chất cơ học của ngà răng. Các dữ liệu chi tiết hơn về các enzym có trách nhiệm và chức năng chi tiết của chúng trong các tình trạng phá hủy ngà răng có thể không chỉ giúp tìm ra các phương pháp phòng ngừa mới và tốt hơn, mà việc bảo tồn tốt hơn ma trận collagenous của ngà răng đã khử khoáng cũng có thể tạo điều kiện cho việc tái khoáng sinh học thực sự, từ đó phục hồi tốt hơn tính toàn vẹn cấu trúc và các tính chất cơ học của răng.\u003C\u002Fjats:p>","\u003Cjats:p>Dentin organic matrix, with type I collagen as the main component, is exposed after demineralization in dentinal caries, erosion or acidic conditioning during adhesive composite restorative treatment. This exposed matrix is prone to slow hydrolytic degradation by host collagenolytic enzymes, matrix metalloproteinases (MMPs) and cysteine cathepsins. Here we review the recent findings demonstrating that inhibition of salivary or dentin endogenous collagenolytic enzymes may provide preventive means against progression of caries or erosion, just as they have been shown to retain the integrity and improve the longevity of resin composite filling bonding to dentin. This paper also presents the case that the organic matrix in caries-affected dentin may not be preserved as intact as previously considered. In partially demineralized dentin, MMPs and cysteine cathepsins with the ability to cleave off the terminal non-helical ends of collagen molecules (telopeptides) may lead to the gradual loss of intramolecular gap areas. This would seriously compromise the matrix ability for intrafibrillar remineralization, which is considered essential in restoring the dentin's mechanical properties. More detailed data of the enzymes responsible and their detailed function in dentin-destructive conditions may not only help to find new and better preventive means, but better preservation of demineralized dentin collagenous matrix may also facilitate true biological remineralization for the better restoration of tooth structural and mechanical integrity and mechanical properties.\u003C\u002Fjats:p>",{"EN":958,"VI":959},"Matrix Metalloproteinases and Other Matrix Proteinases in Relation to Cariology: The Era of ‘Dentin Degradomics'","Matrix Metalloproteinases và Các Proteinase Matrix Khác Liên Quan Đến Nghiên Cứu Sâu Răng: Kỷ Nguyên của ‘Dentin Degradomics'",{"VOID":961},"9822715",{"VOID":963},"10.1159\u002F000363582","PUBLICATION","Auto 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quan trọng của <i>Streptococcus mutans<\u002Fi> trong nguyên nhân và tiến triển của sâu răng là một vấn đề gây tranh cãi, một phần do sự chú ý thái quá đến số lượng của <i>S. mutans<\u002Fi> và sự sản xuất axit trong khi ma trận bên trong mảng bám răng thường bị bỏ qua. <i>S. mutans<\u002Fi> không phải lúc nào cũng chiếm ưu thế trong mảng bám; nhiều sinh vật khác cũng có khả năng sản xuất axit và chịu axit. Cũng cần nhận thức rằng các glucosyltransferase từ <i>S. mutans<\u002Fi> (Gtfs) đóng vai trò quan trọng trong sự phát triển của mảng bám răng có độc lực. Gtfs hút vào men răng, tổng hợp glucan tại chỗ, cung cấp các vị trí cho sự định cư mạnh mẽ của các vi sinh vật và tạo ra một ma trận không hòa tan cho mảng bám. Gtfs cũng bám vào bề mặt của các vi sinh vật miệng khác, chuyển đổi chúng thành các nhà sản xuất glucan. <i>S. mutans<\u002Fi> biểu hiện 3 Gtfs phân tử gen khác nhau; mỗi loại dường như đóng vai trò khác nhau nhưng chồng chéo trong việc hình thành mảng bám có độc lực. GtfC bám vào men răng trong lớp màng trong khi GtfB liên kết chặt chẽ với vi khuẩn, thúc đẩy sự tụ tập chặt chẽ của tế bào, và tăng cường sự kết dính của mảng bám. GtfD tạo thành một polysaccharide hòa tan, dễ chuyển hóa và hoạt động như một chất khởi đầu cho GtfB. Hành vi của các Gtf hòa tan không phản ánh những gì được quan sát với các enzyme được hấp phụ trên bề mặt. Hơn nữa, cấu trúc của ma trận polysaccharide thay đổi theo thời gian do sự tác động của mutanase và dextranase trong mảng bám. Các Gtfs ở các vị trí riêng biệt cung cấp các mục tiêu hóa trị để ngăn ngừa sâu răng. Tuy nhiên, các tác nhân ức chế Gtfs trong dung dịch thường có tác dụng giảm hoặc không có tác dụng đối với các enzyme được hấp phụ. Rõ ràng, các thay đổi cấu hình và phản ứng của Gtfs trên bề mặt là phức tạp và điều chỉnh quá trình tiến triển của sâu răng tại chỗ, cần được nghiên cứu thêm.\u003C\u002Fjats:p>","\u003Cjats:p>The importance of <i>Streptococcus mutans<\u002Fi> in the etiology and pathogenesis of dental caries is certainly controversial, in part because excessive attention is paid to the numbers of <i>S. mutans <\u002Fi>and acid production while the matrix within dental plaque has been neglected. <i>S. mutans<\u002Fi> does not always dominate within plaque; many organisms are equally acidogenic and aciduric. It is also recognized that glucosyltransferases from <i>S. mutans<\u002Fi> (Gtfs) play critical roles in the development of virulent dental plaque. Gtfs adsorb to enamel synthesizing glucans in situ, providing sites for avid colonization by microorganisms and an insoluble matrix for plaque. Gtfs also adsorb to surfaces of other oral microorganisms converting them to glucan producers. <i>S. mutans<\u002Fi> expresses 3 genetically distinct Gtfs; each appears to play a different but overlapping role in the formation of virulent plaque. GtfC is adsorbed to enamel within pellicle whereas GtfB binds avidly to bacteria promoting tight cell clustering, and enhancing cohesion of plaque. GtfD forms a soluble, readily metabolizable polysaccharide and acts as a primer for GtfB. The behavior of soluble Gtfs does not mirror that observed with surface-adsorbed enzymes. Furthermore, the structure of polysaccharide matrix changes over time as a result of the action of mutanases and dextranases within plaque. Gtfs at distinct loci offer chemotherapeutic targets to prevent caries. Nevertheless, agents that inhibit Gtfs in solution frequently have a reduced or no effect on adsorbed enzymes. Clearly, conformational changes and reactions of Gtfs on surfaces are complex and modulate the pathogenesis of dental caries in situ, deserving further investigation.\u003C\u002Fjats:p>",{"EN":1515,"VI":1516},"Biology of <i>Streptococcus mutans-<\u002Fi>Derived Glucosyltransferases: Role in Extracellular Matrix Formation of Cariogenic Biofilms","Sinh học của các glucosyltransferase có nguồn gốc từ <i>Streptococcus mutans<\u002Fi>: Vai trò trong việc hình thành ma trận ngoài tế bào của các biofilm gây sâu răng",{"VOID":1518},"21346355",{"VOID":1520},"10.1159\u002F000324598","2024-12-06T01:01:02.169+00:00",[31],[30],"https:\u002F\u002Fkarger.com\u002FCRE\u002Farticle\u002Fdoi\u002F10.1159\u002F000324598",[1526,1543],{"id":1527,"sortIndex":32,"researcher":28,"roles":1528,"affiliations":1529,"properties":1538,"displayName":1540,"givenName":28,"familyName":28},"97013b1d-32eb-41f3-a4c8-7700b504d803",[],[1530],{"id":1531,"sortIndex":32,"affiliation":1532,"properties":28},"684d5b06-3ac4-4ad6-8f07-8fbdcd598c57",{"id":1531,"createTime":28,"updateTime":28,"relativeEntities":1533,"slug":28,"properties":1534,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1537,"statistic":28},[],{"title":1535},{"EN":1536},"Center for Oral Biology,",[],{"title":1539,"openalex":1541},{"EN":1540},"W.H. 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mòn răng, axit, chế độ ăn uống, yếu tố nguyên nhân",{"VOID":2014},"W1973273827",{"VI":2016,"EN":2017},"\u003Cjats:p>Các axit có nguồn gốc nội tại và ngoại tại được cho là những yếu tố nguyên nhân chính gây ra sự bào mòn răng. Có bằng chứng cho thấy thực phẩm và đồ uống có tính axit đóng vai trò trong sự phát triển của bào mòn. Tuy nhiên, giá trị pH của một chất dinh dưỡng đơn thuần không dự đoán được khả năng gây bào mòn của nó vì nhiều yếu tố khác có thể điều chỉnh quá trình bào mòn. Các yếu tố này bao gồm hóa học (giá trị pK<sub>a <\u002Fsub>, tính bám dính và tính chelat, hàm lượng canxi, phosphate và fluoride), hành vi (thói quen ăn uống và uống nước, phong cách sống, tiêu thụ axit quá mức) và sinh học (tốc độ dòng chảy, khả năng đệm, thành phần nước bọt, sự hình thành màng sinh học, thành phần răng, giải phẫu mô mềm và răng miệng). Sự tương tác giữa bào mòn và ma sát (đặc biệt là các thói quen vệ sinh miệng) có thể là động lực chính dẫn đến biểu hiện lâm sàng của rối loạn này. Các khuyến nghị cho bệnh nhân có nguy cơ mắc bào mòn răng như giảm tiếp xúc với axit thông qua việc giảm tần suất và thời gian tiếp xúc với axit sẽ được thảo luận.\u003C\u002Fjats:p>","\u003Cjats:p>Acids of intrinsic and extrinsic origin are thought to be the main etiologic factors for dental erosion. There is evidence that acidic foodstuffs and beverages play a role in the development of erosion. However, the pH of a dietary substance alone is not predictive of its potential to cause erosion as other factors modify the erosive process. These factors are chemical (pK<sub>a <\u002Fsub>values, adhesion and chelating properties, calcium, phosphate and fluoride content), behavioural (eating and drinking habits, life style, excessive consumption of acids) and biological (flow rate, buffering capacity, composition of saliva, pellicle formation, tooth composition, dental and soft tissue anatomy). The interplay between erosion and abrasion (specially oral hygiene practices) may be the main driver leading to the clinical manifestation of this disorder. Recommendations for patients at risk for dental erosion such as reducing acid exposure by reducing the frequency and contact of acids will be discussed.\u003C\u002Fjats:p>",{"EN":2019,"VI":2020},"The Role of Diet in the Aetiology of Dental Erosion","Vai Trò Của Chế Độ Ăn Trong Nguyên Nhân Của Sự Bào Mòn Răng",{"VOID":2022},"14685022",{"VOID":2024},"10.1159\u002F000074360",[31],[30],"https:\u002F\u002Fkarger.com\u002FCRE\u002Farticle\u002Fdoi\u002F10.1159\u002F000074360",[2029,2048,2063],{"id":2030,"sortIndex":32,"researcher":28,"roles":2031,"affiliations":2032,"properties":2041,"displayName":2045,"givenName":28,"familyName":28},"0ceb3091-a67f-4085-8f43-9418f568a4eb",[],[2033],{"id":2034,"sortIndex":32,"affiliation":2035,"properties":28},"500b1c53-1b50-4298-bf54-d14cba4352c1",{"id":2034,"createTime":28,"updateTime":28,"relativeEntities":2036,"slug":28,"properties":2037,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2040,"statistic":28},[],{"title":2038},{"VI":2039},"Department of Operative, Preventive and Paediatric Dentistry, School of Dental Medicine, University of Bern, Bern, Switzerland",[],{"orcid":2042,"title":2044,"openalex":2046},{"VOID":2043},"https:\u002F\u002Forcid.org\u002F0000-0002-0426-3364",{"EN":2045},"Adrian Lussi",{"VOID":2047},"A5060522829",{"id":2049,"sortIndex":40,"researcher":28,"roles":2050,"affiliations":2051,"properties":2058,"displayName":2060,"givenName":28,"familyName":28},"271d5c4b-87e8-4881-858e-43ea6a8c0e98",[],[2052],{"id":2034,"sortIndex":32,"affiliation":2053,"properties":28},{"id":2034,"createTime":28,"updateTime":28,"relativeEntities":2054,"slug":28,"properties":2055,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2057,"statistic":28},[],{"title":2056},{"VI":2039},[],{"title":2059,"openalex":2061},{"EN":2060},"Thomas Jaeggi",{"VOID":2062},"A5075327190",{"id":2064,"sortIndex":123,"researcher":28,"roles":2065,"affiliations":2066,"properties":2075,"displayName":2079,"givenName":28,"familyName":28},"2fc224fb-e30d-4c1e-b00b-c555567e11d5",[],[2067],{"id":2068,"sortIndex":32,"affiliation":2069,"properties":28},"73a3d458-aff8-467d-adca-aa8fafe4538c",{"id":2068,"createTime":28,"updateTime":28,"relativeEntities":2070,"slug":28,"properties":2071,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2074,"statistic":28},[],{"title":2072},{"EN":2073},"Department of Preventive and Community Dentistry, Indiana University School of Dentistry, Indianapolis, Ind., USA",[],{"orcid":2076,"title":2078,"openalex":2080},{"VOID":2077},"https:\u002F\u002Forcid.org\u002F0000-0001-7499-2282",{"EN":2079},"Domenick T. 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Demineralization and Remineralization of Artificial Enamel Lesions",{"VOID":2229},"6953998",{"VOID":2231},"10.1159\u002F000260599","Author affiliation is blank",[31],"https:\u002F\u002Fkarger.com\u002FCRE\u002Farticle\u002Fdoi\u002F10.1159\u002F000260599",[2236,2253],{"id":2237,"sortIndex":32,"researcher":28,"roles":2238,"affiliations":2239,"properties":2248,"displayName":2250,"givenName":28,"familyName":28},"b8cba100-8281-47a8-a1a3-227118ee9369",[],[2240],{"id":2241,"sortIndex":32,"affiliation":2242,"properties":28},"905a1bb0-5512-422a-8369-120497a3c29f",{"id":2241,"createTime":28,"updateTime":28,"relativeEntities":2243,"slug":28,"properties":2244,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2247,"statistic":28},[],{"title":2245},{"VI":2246},"Department of Dental Materials Science, University of Amsterdam, The Netherlands",[],{"title":2249,"openalex":2251},{"EN":2250},"J.M. ten 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Mảng bám răng đại diện cho một hệ sinh thái vi sinh, trong đó vi khuẩn không phải mutans (chủ yếu là liên cầu không phải mutans và <i>Actinomyces<\u002Fi>) là những vi sinh vật chính chịu trách nhiệm duy trì sự ổn định động động trên bề mặt răng (giai đoạn ổn định động). Sự thích nghi với axit của vi khuẩn và sự lựa chọn axit tiếp theo của vi khuẩn không phải mutans 'pH thấp' đóng vai trò quan trọng trong việc làm mất ổn định tính cân bằng sinh lý của mảng bám bằng cách tạo điều kiện thuận lợi cho việc chuyển dịch cân bằng demineral hóa\u002Fremineral hóa từ 'lợi khoáng ròng' sang 'mất khoáng ròng' (giai đoạn axitogenic). Khi môi trường axit đã được thiết lập, liên cầu mutans và các vi khuẩn aciduric khác có thể gia tăng và thúc đẩy sự phát triển tổn thương bằng cách duy trì một môi trường được đặc trưng bởi 'mất khoáng ròng' (giai đoạn aciduric). Do đó, tỷ lệ cao của liên cầu mutans và\u002Fhoặc các vi khuẩn aciduric khác có thể được coi là dấu hiệu sinh học của các vị trí có sự tiến triển sâu răng nhanh chóng đặc biệt. Chuỗi sự kiện này có thể thay đổi kết cấu bề mặt của các tổn thương sâu răng từ nhẵn sang thô (men) hoặc cứng sang mềm (ngà). Những đặc điểm bề mặt lâm sàng này có thể được đảo ngược ở bất kỳ giai đoạn phát triển tổn thương nào miễn là các thuộc tính acidogenic\u002Faciduric của màng sinh học được giải quyết. Từ góc độ sinh thái, việc mô tả vi khuẩn nào có liên quan đến sâu răng là quan trọng nhưng cũng cần biết vi khuẩn đang làm gì.\u003C\u002Fjats:p>","\u003Cjats:p>In this essay we propose an extension of the caries ecological hypothesis to explain the relation between dynamic changes in the phenotypic\u002Fgenotypic properties of plaque bacteria and the demineralization\u002Fremineralization balance of the caries process. Dental plaque represents a microbial ecosystem in which non-mutans bacteria (mainly non-mutans streptococci and <i>Actinomyces<\u002Fi>) are the key microorganisms responsible for maintaining dynamic stability on the tooth surface (dynamic stability stage). Microbial acid adaptation and subsequent acid selection of ‘low-pH’ non-mutans bacteria play a critical role for destabilizing the homeostasis of the plaque by facilitating a shift of the demineralization\u002Fremineralization balance from ‘net mineral gain’ to ‘net mineral loss’ (acidogenic stage). Once the acidic environment has been established, mutans streptococci and other aciduric bacteria may increase and promote lesion development by sustaining an environment characterized by ‘net mineral loss’ (aciduric stage). Hence, high proportions of mutans streptococci and\u002For other aciduric bacteria may be considered biomarkers of sites of particularly rapid caries progression. This cascade of events may change the surface texture of caries lesions from smooth to rough (enamel) or hard to soft (dentin). These clinical surface features can be reversed at any stage of lesion development provided that the acidogenic\u002Faciduric properties of the biofilm are resolved. From an ecological point of view it is therefore not only important to describe which bacteria are involved in caries, but also to know what the bacteria are doing.\u003C\u002Fjats:p>",{"EN":2329,"VI":2330},"Caries Ecology Revisited: Microbial Dynamics and the Caries Process","Tái xem xét sinh thái học sâu răng: Động lực vi sinh và quá trình sâu 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tiêu:<\u002Fi> Mục tiêu của nghiên cứu này là đánh giá tính tái lập giữa các người đánh giá và trong cùng một người đánh giá cũng như độ chính xác trong việc phát hiện và đánh giá sâu răng nhai trên răng người đã được nhổ bằng cách sử dụng một phương pháp thị giác mới được phát triển để chẩn đoán sâu răng (Hệ thống Phát hiện và Đánh giá Sâu răng Quốc tế, ICDAS-II). Cắt lát liên tục và kính hiển vi được sử dụng làm 'tiêu chuẩn vàng'. <i>Phương pháp:<\u002Fi> Các bề mặt nhai của 100 chiếc răng đã được 4 nha sĩ kiểm tra bằng các điểm số đánh giá ICDAS-II từ 0 đến 6. Sau đó, các chiếc răng được cắt lát liên tiếp và đánh giá độ sâu của tổn thương bằng hai hệ thống phân loại mô học. <i>Kết quả:<\u002Fi> Các giá trị kappa có trọng số cho tính tái lập giữa các người đánh giá và trong cùng một người đánh giá cho việc kiểm tra ICDAS-II là 0.62–0.83. Có một mối quan hệ mức độ trung bình giữa các cuộc kiểm tra thị giác và cả hai cuộc kiểm tra mô học (r<sub>s<\u002Fsub> = 0.43–0.72). Tại ngưỡng chẩn đoán D1 (tổn thương men và ngà) độ đặc hiệu là 0.74–0.91 và độ nhạy là 0.59–0.73. Tại ngưỡng chẩn đoán D3 (tổn thương ngà) độ đặc hiệu là 0.82–0.94 và độ nhạy là 0.48–0.83 cho 4 người đánh giá. <i>Kết luận:<\u002Fi> Hệ thống ICDAS-II đã cho thấy tính tái lập và độ chính xác chẩn đoán cho việc phát hiện sâu răng nhai ở các giai đoạn khác nhau của quá trình bệnh lý, điều này có sự so sánh được với các dữ liệu đã được báo cáo trước đó sử dụng các hệ thống phân loại thị giác tương tự.","\u003Cjats:p><i>Aim:<\u002Fi> The aim of this study was to assess inter- and intra-examiner reproducibility and accuracy in the detection and assessment of occlusal caries in extracted human teeth using a newly developed visual method for caries diagnosis (International Caries Detection and Assessment System, ICDAS-II). Serial sectioning and microscopy were used as the ‘gold standard’. <i>Methods:<\u002Fi> The occlusal surfaces of 100 teeth were examined by 4 dentists using the ICDAS-II graded scores 0–6. Thereafter the teeth were serially sectioned and assessed for depth of the lesion with two histological classification systems. <i>Results:<\u002Fi> The weighted kappa values for inter- and intra-examiner reproducibility for the ICDAS-II examination were 0.62–0.83. There was a moderate relationship between the visual and both histological examinations (r<sub>s<\u002Fsub> = 0.43–0.72). At the D1 diagnostic threshold (enamel and dentine lesions) specificity was 0.74–0.91 and sensitivity was 0.59–0.73. 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Hai trăm năm mươi hai trẻ em (36–59 tháng tuổi) tại Amparo, Brazil, đã được hai người khám sử dụng ICDAS-II hoặc tiêu chí của WHO. Các chỉ số dmf-t, dmf-s, tỷ lệ sâu răng và thời gian khám bệnh đã được tính toán bằng cả hai hệ thống. ICDAS-II có thể so sánh được với các tiêu chí chuẩn khi điểm cắt là 3. Thời gian khám bằng ICDAS-II lâu gấp đôi so với tiêu chí của WHO. Kết luận, ICDAS-II, ngoài việc cung cấp thông tin về các tổn thương sâu răng không có lỗ, còn có thể tạo ra dữ liệu so sánh được với các cuộc khảo sát trước đó đã sử dụng tiêu chí của WHO.\u003C\u002Fjats:p>","\u003Cjats:p>This study evaluated the feasibility of using the International Caries Detection and Assessment System (ICDAS-II) in epidemiological surveys and compared ICDAS with WHO criteria. Two hundred and fifty-two children (36–59 months old) in Amparo, Brazil, were each examined by 2 examiners using ICDAS-II or WHO criteria. 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