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              \u003Cjats:p>Pouch function after proctocolectomy and ileal J pouch-anal anastomosis was assessed at 1 and 5 years in 41 patients with familial adenomatous polyposis. The mean(s.d.) stool frequency per 24 h decreased from 4·4(1·7) to 3·9(1·8) (P < 0·05), the mean(s.d.) nocturnal stool frequency fell from 0·6(1·0) to 0·3(0·6) (P < 0·05), and the number of patients having nocturnal bowel movements decreased from 16 to seven (P < 0·05). At 5 years, only one patient still followed a strict diet (versus ten at 1 year, P < 0·05) and only two needed antidiarrhoeal medication (versus ten at 1 year, P < 0·05). There were no episodes of pouchitis or late reservoir-related complications. The function of ileal pouch-anal anastomosis improves over time in patients with familial adenomatous polyposis.\u003C\u002Fjats:p>",{"EN":887},"Function of ileal J pouch-anal anastomosis in patients with familial adenomatous polyposis",{"VOID":889},"8392425",{"VOID":891},"10.1002\u002Fbjs.1800800638",[111],"https:\u002F\u002Facademic.oup.com\u002Fbjs\u002Farticle\u002F80\u002F6\u002F765\u002F6175726",[895,914,929,946,961,976],{"id":896,"sortIndex":25,"researcher":24,"roles":897,"affiliations":898,"properties":907,"displayName":911,"givenName":24,"familyName":24},"09c6af2b-d413-4cc1-8bed-5d65ee0e0b88",[],[899],{"id":900,"sortIndex":25,"affiliation":901,"properties":24},"03580cd0-e3db-44ab-b71f-c6d4682260a6",{"id":900,"createTime":24,"updateTime":24,"relativeEntities":902,"slug":24,"properties":903,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":906,"statistic":24},[],{"title":904},{"EN":905},"Department of Alimentary Tract Surgery, Hǒpital Saint-Antoine, 184 Rue du Faubourg Saint-Antoine, 75012 Paris, France",[],{"orcid":908,"title":910,"openalex":912},{"VOID":909},"https:\u002F\u002Forcid.org\u002F0009-0005-0653-2985",{"EN":911},"C. 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1980, Proctocolectomy with ileal reservoir and anal anastomosis, Br J Surg, 67, 533, 10.1002\u002Fbjs.1800670802",{"doi":1047},"10.1002\u002Fbjs.1800670802",{"id":24,"text":1049,"url":24,"identifiers":1050},"Utsunomiya, 1980, Total colectomy, mucosal proctectomy, and ileoanal anastomosis, Dis Colon Rectum, 23, 459, 10.1007\u002FBF02987076",{"doi":1051},"10.1007\u002FBF02987076",{"id":24,"text":1053,"url":24,"identifiers":1054},"Thomson, 1988, Leeds Castle Polyposis Group meeting, Dis Colon Rectum, 31, 613, 10.1007\u002FBF02556797",{"doi":1055},"10.1007\u002FBF02556797",{"id":24,"text":1057,"url":24,"identifiers":1058},"Sarre, 1987, Colectomy with ileorectal anastomosis for familial adenomatous polyposis: the risk of rectal cancer, Surgery, 101, 20",{},{"id":24,"text":1060,"url":24,"identifiers":1061},"Moertel, 1970, Surgical management of multiple polyposis, Arch Surg, 100, 521, 10.1001\u002Farchsurg.1970.01340220197033",{"doi":1062},"10.1001\u002Farchsurg.1970.01340220197033",{"id":24,"text":1064,"url":24,"identifiers":1065},"Bess, 1980, Rectal cancer following colectomy for polyposis, Arch Surg, 115, 460, 10.1001\u002Farchsurg.1980.01380040084015",{"doi":1066},"10.1001\u002Farchsurg.1980.01380040084015",{"id":24,"text":1068,"url":24,"identifiers":1069},"Bussey, 1985, The rectum in adenomatous polyposis: the St Mark's policy, Br J Surg, 72, S29-31",{},{"id":24,"text":1071,"url":24,"identifiers":1072},"Dozois, 1989, Ileal pouch-anal anastomosis: comparison of results in familial adenomatous polyposis and chronic ulcerative colitis, Ann Surg, 210, 268, 10.1097\u002F00000658-198909000-00002",{"doi":1073},"10.1097\u002F00000658-198909000-00002",{"id":24,"text":1075,"url":24,"identifiers":1076},"François, 1989, Small intestinal obstruction complicating ileal pouch-anal anastomosis, Ann Surg, 209, 46, 10.1097\u002F00000658-198901000-00007",{"doi":1077},"10.1097\u002F00000658-198901000-00007",{"id":24,"text":1079,"url":24,"identifiers":1080},"Matikainen, 1990, Ileoanal anastomosis without covering ileostomy, Dis Colon Rectum, 33, 384, 10.1007\u002FBF02156263",{"doi":1081},"10.1007\u002FBF02156263",{"id":24,"text":1083,"url":24,"identifiers":1084},"Ambroze, 1992, Familial adenomatous polyposis: results following ileal pouch-anal anastomosis and ileorectostomy, Dis Colon Rectum, 35, 12, 10.1007\u002FBF02053332",{"doi":1085},"10.1007\u002FBF02053332",{"id":24,"text":1087,"url":24,"identifiers":1088},"Pemberton, 1987, Ileal pouch anal anastomosis for chronic ulcerative colitis-long term results, Ann Surg, 206, 504, 10.1097\u002F00000658-198710000-00011",{"doi":1089},"10.1097\u002F00000658-198710000-00011",{"id":24,"text":1091,"url":24,"identifiers":1092},"Berk, 1988, Surgical aspects of familial adenomatous polyposis, Int J Colorectal Dis, 3, 1, 10.1007\u002FBF01649676",{"doi":1093},"10.1007\u002FBF01649676",{"id":24,"text":1095,"url":24,"identifiers":1096},"Nicholls, 1987, Restorative proctocolectomy: the four-loop (W) reservoir, Br J Surg, 74, 564, 10.1002\u002Fbjs.1800740705",{"doi":1097},"10.1002\u002Fbjs.1800740705",{"id":24,"text":1099,"url":24,"identifiers":1100},"Öresland, 1989, The clinical and functional outcome after restorative proctocolectomy: a prospective study in 100 patients, Int J Colorectal Dis, 4, 50, 10.1007\u002FBF01648551",{"doi":1101},"10.1007\u002FBF01648551",{"id":24,"text":1103,"url":24,"identifiers":1104},"Metcalf, 1985, Ileal J pouch-anal anastomosis: clinical outcome, Ann Surg, 202, 735, 10.1097\u002F00000658-198512000-00013",{"doi":1105},"10.1097\u002F00000658-198512000-00013",{"id":24,"text":1107,"url":24,"identifiers":1108},"Becker, 1986, Ileal pouch-anal anastomosis. A single surgeon's experience with 100 consecutive cases, Ann Surg, 204, 375, 10.1097\u002F00000658-198610000-00005",{"doi":1109},"10.1097\u002F00000658-198610000-00005",{"id":24,"text":1111,"url":24,"identifiers":1112},"Wexner, 1989, Long-term functional analysis of the ileoanal reservoir, Dis Colon Rectum, 32, 460, 10.1007\u002FBF02554497",{"doi":1113},"10.1007\u002FBF02554497",{"id":24,"text":1115,"url":24,"identifiers":1116},"Sagar, 1991, Correlation between laboratory findings and clinical outcome after restorative proctocolectomy serial studies in 20 patients with end-to-end pouch-anal anastomosis, Br J Surg, 78, 67, 10.1002\u002Fbjs.1800780121",{"doi":1117},"10.1002\u002Fbjs.1800780121",{"id":24,"text":1119,"url":24,"identifiers":1120},"Nasmyth, 1986, Comparison of the function of triplicated and duplicated pelvic ileal reservoirs after mucosal proctectomy and ileo-anal anastomosis for ulcerative colitis and adenomatous polyposis, Br J Surg, 73, 361, 10.1002\u002Fbjs.1800730511",{"doi":1121},"10.1002\u002Fbjs.1800730511",{"id":24,"text":1123,"url":24,"identifiers":1124},"Becker, 1985, Functional assessment after colectomy, mucosal proctectomy, and endorectal ileoanal pull-through, World J Surg, 9, 598, 10.1007\u002FBF01656061",{"doi":1125},"10.1007\u002FBF01656061",{"id":24,"text":1127,"url":24,"identifiers":1128},"Keighley, 1987, Discrimination is not impaired by excision of the anal transition zone after restorative proctocolectomy, Br J Surg, 74, 1118, 10.1002\u002Fbjs.1800741215",{"doi":1129},"10.1002\u002Fbjs.1800741215",{"id":24,"text":1131,"url":24,"identifiers":1132},"O'Connell, 1988, Anal canal pressure and mobility after ileoanal anastomosis, Surg Gynecol Obstet, 166, 47",{},{"id":24,"text":1134,"url":24,"identifiers":1135},"Winslet, 1987, Factors influencing the outcome of restorative proctocolectomy, Gut, 28, A1365-6",{},{"id":24,"text":1137,"url":24,"identifiers":1138},"Madden, 1990, Inflammation in ileal reservoirs: ‚pouchitis’︁, Gut, 31, 247, 10.1136\u002Fgut.31.3.247",{"doi":1139},"10.1136\u002Fgut.31.3.247",{"id":24,"text":1141,"url":24,"identifiers":1142},"Spigelman, 1990, Desmoid tumours and viruses, Int J Colorectal Dis, 5, 53",{},{"id":24,"text":1144,"url":24,"identifiers":1145},"Madden, 1991, Comparison of morbidity and function after colectomy with ileorectal anastomosis or restorative proctocolectomy for familial adenomatous polyposis, Br J Surg, 78, 789, 10.1002\u002Fbjs.1800780708",{"doi":1146},"10.1002\u002Fbjs.1800780708",{"id":24,"text":1148,"url":24,"identifiers":1149},"Watne, 1983, The occurrence of carcinoma of the rectum following ileoproctostomy for familial polyposis, Ann Surg, 197, 550, 10.1097\u002F00000658-198305000-00008",{"doi":1150},"10.1097\u002F00000658-198305000-00008",{"id":1152,"createTime":1153,"updateTime":1154,"relativeEntities":1155,"slug":1156,"properties":1157,"entityType":107,"verifyStatus":108,"verifyTime":1153,"verifyNote":109,"languages":1172,"translateLanguages":24,"viewCount":25,"primaryUrl":1173,"fullTextUrl":24,"authors":1174,"publicationType":147,"publisherRelationship":1279,"citationCount":25,"citationInfo":1325,"publishDate":1328,"publishYear":1326,"citationAnalyzeStatus":23,"lastCitationAnalyze":1329,"indexDatabases":1330,"openAccess":24,"references":1331,"isForceReanalyzing":277},"e6d7c513-e211-42ad-80c7-5aafa61e610f","2024-10-03T11:15:51.352+00:00","2026-05-22T15:02:07.398+00:00",[],"Adjuvant-regional-chemotherapy-after-hepatic-resection-for-colorectal-metastases",{"mag":1158,"gsPaper":1160,"openalex":1162,"abstract":1164,"title":1166,"pm":1168,"doi":1170},{"VOID":1159},"2106894333",{"VOID":1161},"[\"11192176818050883532\"]",{"VOID":1163},"W2106894333",{"EN":1165},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Background\u003C\u002Fjats:title>\n                  \u003Cjats:p>This study explored the possibility of achieving a better survival rate and reduced recurrence in the remaining liver in patients with colorectal hepatic metastases undergoing hepatic resection. Adjuvant postoperative regional chemotherapy was administered via the hepatic artery or the portal vein.\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Methods\u003C\u002Fjats:title>\n                  \u003Cjats:p>A retrospective study was performed on 174 patients after hepatic resection for colorectal metastases. These comprised 78 patients who had hepatic artery infusion (HAI) chemotherapy (HAI group), 30 who had portal vein infusion (PVI) chemotherapy (PVI group) and 66 who had no regional chemotherapy (resection alone group). The three groups were compared with one another in terms of complications, survival rate and patterns of recurrence.\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Results\u003C\u002Fjats:title>\n                  \u003Cjats:p>Severe complications did not occur at any point during adjuvant HAI or PVI chemotherapy. The 5-year disease-free survival rate of patients in the HAI, PVI and resection alone groups were 35, 13 and 9 per cent respectively, including six hospital deaths. Patients in the HAI group showed significantly improved recurrence rates in the remaining liver compared with the resection alone group (P = 0·03), and more prolonged disease-free and overall survival than those in the PVI (P = 0·01 and P = 0·02 respectively) and resection alone (P = 0·0001 and P = 0·0006 respectively) groups.\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Conclusion\u003C\u002Fjats:title>\n                  \u003Cjats:p>This study suggests that adjuvant HAI chemotherapy after hepatic resection may have therapeutic potential for improved management of patients with colorectal metastases.\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>",{"EN":1167},"Adjuvant regional chemotherapy after hepatic resection for colorectal 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A prognostic scoring system to improve case selection, based on 1568 patients. Association Francaise de Chirurgie, Cancer, 77, 1254, 10.1002\u002F(SICI)1097-0142(19960401)77:7\u003C1254::AID-CNCR5>3.0.CO;2-I",{"doi":1346},"10.1002\u002F(SICI)1097-0142(19960401)77:7\u003C1254::AID-CNCR5>3.0.CO;2-I",{"id":24,"text":1348,"url":24,"identifiers":1349},"Laffer, 1995, Intraportal chemotherapy for colorectal hepatic metastases, World J Surg, 19, 246, 10.1007\u002FBF00308634",{"doi":1350},"10.1007\u002FBF00308634",{"id":24,"text":1352,"url":24,"identifiers":1353},"Finlay, 1986, Occult hepatic metastases in colorectal carcinoma, Br J Surg, 73, 732, 10.1002\u002Fbjs.1800730918",{"doi":1354},"10.1002\u002Fbjs.1800730918",{"id":24,"text":1356,"url":24,"identifiers":1357},"Isono, 1990, Clinicopathological significance of intrahepatic micrometastases in hepatic metastatic carcinomas, Nippon Geka Gakkai Zasshi, 91, 1778",{},{"id":24,"text":1359,"url":24,"identifiers":1360},"Allen-Mersh, 1994, Quality of life and survival with continuous hepatic-artery floxuridine infusion for colorectal liver metastases, Lancet, 344, 1255, 10.1016\u002FS0140-6736(94)90750-1",{"doi":1361},"10.1016\u002FS0140-6736(94)90750-1",{"id":24,"text":1363,"url":24,"identifiers":1364},"Kemeny, 1994, Phase II study of hepatic arterial floxuridine, leucovorin, and dexamethasone for unresectable liver metastases from colorectal carcinoma, J Clin Oncol, 12, 2288, 10.1200\u002FJCO.1994.12.11.2288",{"doi":1365},"10.1200\u002FJCO.1994.12.11.2288",{"id":24,"text":1367,"url":24,"identifiers":1368},"Vauthey, 1996, Arterial therapy of hepatic colorectal metastases, Br J Surg, 83, 447, 10.1002\u002Fbjs.1800830405",{"doi":1369},"10.1002\u002Fbjs.1800830405",{"id":24,"text":1371,"url":24,"identifiers":1372},"Taylor, 1985, A randomized controlled trial of adjuvant portal vein cytotoxic perfusion in colorectal cancer, Br J Surg, 72, 359, 10.1002\u002Fbjs.1800720509",{"doi":1373},"10.1002\u002Fbjs.1800720509",{"id":24,"text":1375,"url":24,"identifiers":1376},"Fielding, 1992, Randomised controlled trial of adjuvant chemotherapy by portal-vein perfusion after curative resection for colorectal adenocarcinoma, Lancet, 340, 502, 10.1016\u002F0140-6736(92)91708-G",{"doi":1377},"10.1016\u002F0140-6736(92)91708-G",{"id":24,"text":1379,"url":24,"identifiers":1380},"Swiss Group for Clinical Cancer Research (SAKK), 1995, Long-term results of single course of adjuvant intraportal chemotherapy for colorectal cancer, Lancet, 345, 349, 10.1016\u002FS0140-6736(95)90340-2",{"doi":1381},"10.1016\u002FS0140-6736(95)90340-2",{"id":24,"text":1383,"url":24,"identifiers":1384},"Kaplan, 1958, Nonparametric estimation from incomplete observations, J Am Stat Assoc, 53, 457, 10.1080\u002F01621459.1958.10501452",{"doi":1385},"10.1080\u002F01621459.1958.10501452",{"id":24,"text":1387,"url":24,"identifiers":1388},"Mantel, 1966, Evaluation of survival data and two new rank order statistics arising in its consideration, Cancer Chemother Rep, 50, 163",{},{"id":24,"text":1390,"url":24,"identifiers":1391},"Seldinger, 1953, Catheter replacement of the needle in percutaneous arteriography. A new technique, Acta Radiol, 39, 368, 10.3109\u002F00016925309136722",{"doi":1392},"10.3109\u002F00016925309136722",{"id":24,"text":1394,"url":24,"identifiers":1395},"Curley, 1993, Adjuvant hepatic arterial infusion chemotherapy after curative resection of colorectal liver metastases, Am J Surg, 166, 743, 10.1016\u002FS0002-9610(05)80691-9",{"doi":1396},"10.1016\u002FS0002-9610(05)80691-9",{"id":24,"text":1398,"url":24,"identifiers":1399},"Nonami, 1997, Regional adjuvant chemotherapy after partial hepatectomy for metastatic colorectal carcinoma, Semin Oncol, 24, 130",{},{"id":24,"text":1401,"url":24,"identifiers":1402},"Hugh, 1997, Management strategies for colorectal liver metastases. Part 1, Surg Oncol, 6, 19, 10.1016\u002FS0960-7404(97)00002-9",{"doi":1403},"10.1016\u002FS0960-7404(97)00002-9",{"id":24,"text":1405,"url":24,"identifiers":1406},"Strohmeyer, 1987, Angioarchitecture and blood supply of micro- and macrometastases in human livers. 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A total of 322 consecutive patients underwent 324 gastroenterostomies; 35 experienced delayed return of gastric emptying. Regression analysis demonstrated preoperative obstruction to be the most significant factor (P < 0·001). Vagotomy was not an independent variable. Age, sex, size of stoma, anastomotic technique, albumin and experience of the operator were not significant factors. Gastroenterostomy in the presence of ‘gastric atony’ was likely to produce DRGE. In all, 86 per cent of cases resolved spontaneously. Only one case of DRGE was found to have a mechanical cause. 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1936, The complications of gastroenterostomy, Surg Clin N Am, 16, 805",{},{"id":24,"text":1568,"url":24,"identifiers":1569},"Jones, 1933, Postoperative nutritional oedema, Arch Surg, 27, 159, 10.1001\u002Farchsurg.1933.01170070162006",{"doi":1570},"10.1001\u002Farchsurg.1933.01170070162006",{"id":24,"text":1572,"url":24,"identifiers":1573},"Dragstedt, 1951, Appraisal of vagotomy for peptic ulcer after 7 years, JAMA, 145, 792",{},{"id":24,"text":1575,"url":24,"identifiers":1576},"Nelson, 1967, Alterations in muscular and electrical activity of the stomach following vagotomy, Arch Surg, 94, 821, 10.1001\u002Farchsurg.1967.01330120075015",{"doi":1577},"10.1001\u002Farchsurg.1967.01330120075015",{"id":24,"text":1579,"url":24,"identifiers":1580},"Weinstein, 1955, Gastroenterostomy and vagotomy in the treatment of duodenal ulcer, Ann Surg, 141, 482, 10.1097\u002F00000658-195504000-00008",{"doi":1581},"10.1097\u002F00000658-195504000-00008",{"id":24,"text":1583,"url":24,"identifiers":1584},"Harper, 1966, Gastric dysfunction after vagotomy, Am J Surg, 112, 94, 10.1016\u002FS0002-9610(66)91066-X",{"doi":1585},"10.1016\u002FS0002-9610(66)91066-X",{"id":24,"text":1587,"url":24,"identifiers":1588},"Bergin, 1959, Gastric atonia and delayed gastric emptying after vagotomy for obstructing ulcer, Am J Surg, 98, 612, 10.1016\u002F0002-9610(59)90046-7",{"doi":1589},"10.1016\u002F0002-9610(59)90046-7",{"id":24,"text":1591,"url":24,"identifiers":1592},"Kraft, 1964, Post vagotomy gastric atony, Arch Surg, 88, 865, 10.1001\u002Farchsurg.1964.01310230141027",{"doi":1593},"10.1001\u002Farchsurg.1964.01310230141027",{"id":24,"text":1595,"url":24,"identifiers":1596},"Hermann, 1970, Management of prolonged gastric retention after vagotomy and drainage, Surg Gynec Obstet, 130, 1044",{},{"id":24,"text":1598,"url":24,"identifiers":1599},"Capper, 1965, Vagotomy, Medical Annual, 49",{},{"id":24,"text":1601,"url":24,"identifiers":1602},"Moore, 1947, Resection of the vagus nerves in peptic ulcer, JAMA, 133, 741, 10.1001\u002Fjama.1947.02880110007003",{"doi":1603},"10.1001\u002Fjama.1947.02880110007003",{"id":24,"text":1605,"url":24,"identifiers":1606},"Moody, 1984, Principles of Surgery, 4th, 1127",{},{"id":24,"text":1608,"url":24,"identifiers":1609},"Ellis, 1966, Clinical and radiological study of vagotomy and gastric drainage in the treatment of pyloric stenosis due to duodenal obstruction, Gut, 7, 671, 10.1136\u002Fgut.7.6.671",{"doi":1610},"10.1136\u002Fgut.7.6.671",{"id":24,"text":1612,"url":24,"identifiers":1613},"Sarr, 1981, Role of gastroenterostomy in patients with unresectable carcinoma of the pancreas, Surg Gynec Obstet, 152, 597",{},{"id":24,"text":1615,"url":24,"identifiers":1616},"Schantz, 1984, Palliative gastroenterostomy for pancreatic cancer, Am J Surg, 147, 793, 10.1016\u002F0002-9610(84)90203-4",{"doi":1617},"10.1016\u002F0002-9610(84)90203-4",{"id":24,"text":1619,"url":24,"identifiers":1620},"McLelland, 1987, Relief of acute persistent post-vagotomy gastric atony by metoclopramide, Ann Surg, 188, 439",{},{"id":24,"text":1622,"url":24,"identifiers":1623},"Sheiner, 1976, Drug therapy for postvagotomy gastric stasis, Br J Surg, 63, 608, 10.1002\u002Fbjs.1800630812",{"doi":1624},"10.1002\u002Fbjs.1800630812",{"id":24,"text":1626,"url":24,"identifiers":1627},"Way",{},{"id":24,"text":1629,"url":24,"identifiers":1630},"Gibson, 1902, The creation of an artificial valvula fistula (a) in the treatment of chronic colitis and (b) as an adjunct to certain operations on the stomach, Boston M.&S.J., 147, 341, 10.1056\u002FNEJM190209251471301",{"doi":1631},"10.1056\u002FNEJM190209251471301",{"id":24,"text":1633,"url":24,"identifiers":1634},"Allen, 1902, Jejunostomy for the relief of non-functioning gastroenterostomy stoma, Surgery, 9, 163",{},{"id":1636,"createTime":1637,"updateTime":1638,"relativeEntities":1639,"slug":1640,"properties":1641,"entityType":107,"verifyStatus":108,"verifyTime":1637,"verifyNote":109,"languages":1656,"translateLanguages":24,"viewCount":25,"primaryUrl":1657,"fullTextUrl":24,"authors":1658,"publicationType":147,"publisherRelationship":1676,"citationCount":25,"citationInfo":1722,"publishDate":1725,"publishYear":1723,"citationAnalyzeStatus":23,"lastCitationAnalyze":1638,"indexDatabases":1726,"openAccess":24,"references":1727,"isForceReanalyzing":277},"5a6bb836-9b4e-43e6-806c-2296d45006fd","2024-10-14T13:27:24.442+00:00","2026-05-05T19:49:35.062+00:00",[],"Carcinoma-of-the-stomach-following-partial-gastrectomy-for-benign-gastroduodenal-lesions",{"mag":1642,"gsPaper":1644,"openalex":1646,"abstract":1648,"title":1650,"pm":1652,"doi":1654},{"VOID":1643},"2029102795",{"VOID":1645},"[\"13282701547128507532\"]",{"VOID":1647},"W2029102795",{"EN":1649},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\n               \u003Cjats:p>Thirty-six patients presenting with a carcinoma in their gastric remnant following operation for benign lesions have been studied. The original pathology was found to be a gastric ulcer in 22 of 28 patients whose initial operation was undertaken at St James's Hospital. This represents an incidence of at least 1 carcinoma appearing for every 76 patients undergoing partial gastrectomy for gastric ulceration. Carcinoma is far more likely to develop in the stomach following partial gastrectomy when the original lesion is a gastric ulcer rather than a duodenal ulcer.\u003C\u002Fjats:p>",{"EN":1651},"Carcinoma of the stomach following partial gastrectomy for benign gastroduodenal lesions",{"VOID":1653},"4821002",{"VOID":1655},"10.1002\u002Fbjs.1800610319",[111],"https:\u002F\u002Facademic.oup.com\u002Fbjs\u002Farticle\u002F61\u002F3\u002F244\u002F6190571",[1659],{"id":1660,"sortIndex":25,"researcher":24,"roles":1661,"affiliations":1662,"properties":1671,"displayName":1673,"givenName":24,"familyName":24},"2d5ab7b2-e679-4912-9c03-016303132e60",[],[1663],{"id":1664,"sortIndex":25,"affiliation":1665,"properties":24},"9f3699a7-316a-4b0c-a2e5-319caad0c03b",{"id":1664,"createTime":24,"updateTime":24,"relativeEntities":1666,"slug":24,"properties":1667,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1670,"statistic":24},[],{"title":1668},{"EN":1669},"St James's Hospital, London",[],{"title":1672,"openalex":1674},{"EN":1673},"J. C. Nicholls",{"VOID":1675},"A5081344047",{"url":24,"publisher":1677,"properties":1715},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1678,"slug":10,"properties":1679,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":1684,"manageAffiliations":1689,"indexDatabases":1700,"url":83,"thumbnailPath":24,"statistic":24,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":1680,"eissn":1681,"issn":1682,"title":1683},{"VOID":13},{"VOID":15},{"VOID":17},{"EN":19},[1685],{"id":28,"createTime":24,"updateTime":24,"relativeEntities":1686,"label":1687,"description":1688,"parentId":24,"standard":24,"scholarHubFieldId":24},[],{"EN":31},{},[1690,1695],{"id":35,"createTime":24,"updateTime":24,"relativeEntities":1691,"slug":24,"properties":1692,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1694,"statistic":24},[],{"title":1693},{"EN":39},[],{"id":42,"createTime":24,"updateTime":24,"relativeEntities":1696,"slug":24,"properties":1697,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1699,"statistic":24},[],{"title":1698},{"EN":46},[],[1701,1708],{"id":50,"indexDatabase":1702,"url":63,"indexYears":24,"academicFieldIds":1707,"indexDatabaseRanking":24},{"id":52,"createTime":24,"updateTime":24,"relativeEntities":1703,"label":1704,"description":1705,"key":59,"publicationTags":1706,"standard":24},[],{"EN":55,"VI":55},{"EN":57,"VI":58},[61,62],[65],{"id":67,"indexDatabase":1709,"url":78,"indexYears":79,"academicFieldIds":1714,"indexDatabaseRanking":82},{"id":69,"createTime":24,"updateTime":24,"relativeEntities":1710,"label":1711,"description":1712,"key":75,"publicationTags":1713,"standard":24},[],{"EN":72,"VI":72},{"EN":72,"VI":74},[77],[81],{"issue":1716,"pages":1718,"volume":1720},{"VOID":1717},"3",{"VOID":1719},"244-249",{"VOID":1721},"61",{"total":25,"publishYear":1723,"statisticByYear":1724},1974,{},"1974-03-01",[61,82],[1728,1731,1735,1738,1741,1744,1747,1750,1754,1758,1761,1764,1768,1771,1775,1779,1783,1787,1790,1793,1796,1799],{"id":24,"text":1729,"url":24,"identifiers":1730},"Aird, 1957, A Comparison to Surgical Studies, 2nd, 755",{},{"id":24,"text":1732,"url":24,"identifiers":1733},"Burns, 1967, The association of gastric carcinoma with duodenal ulceration, Br. J. Surg., 54, 174, 10.1002\u002Fbjs.1800540305",{"doi":1734},"10.1002\u002Fbjs.1800540305",{"id":24,"text":1736,"url":24,"identifiers":1737},"Debray, 1958, Stump carcinoma after gastric resection for ulcer, Schweiz. Med. Wochenschr., 88, 631",{},{"id":24,"text":1739,"url":24,"identifiers":1740},"Desmond, 1974",{},{"id":24,"text":1742,"url":24,"identifiers":1743},"Graves, 1971, Gastric carcinoma developing after surgery for peptic ulcer, Am. Surg., 37, 73",{},{"id":24,"text":1745,"url":24,"identifiers":1746},"Gray, 1949, The significance of an ulcerating lesion in the stomach following gastroenterostomy, Surg. Gynecol. Obstet., 89, 285",{},{"id":24,"text":1748,"url":24,"identifiers":1749},"Heinzel, 1954, Magencarcinome nach früherer Resektion wegen Ulcus ventriculi bzw. duodeni, Arch. Klin. Chir., 278, 86",{},{"id":24,"text":1751,"url":24,"identifiers":1752},"Helsingen, 1956, Cancer development in the gastric stump after partial gastrectomy for ulcer, Ann. Surg., 143, 173, 10.1097\u002F00000658-195614320-00003",{"doi":1753},"10.1097\u002F00000658-195614320-00003",{"id":24,"text":1755,"url":24,"identifiers":1756},"De Jode, 1961, Gastric carcinoma following gastroenterostomy and partial gastrectomy, Br. J. Surg., 48, 512, 10.1002\u002Fbjs.18004821108",{"doi":1757},"10.1002\u002Fbjs.18004821108",{"id":24,"text":1759,"url":24,"identifiers":1760},"Kuhlmayer, 1954, Das Magen-stumpfcarcinom als Spätproblem der Ulcus-chirurgie, Arch. Klin. Chir., 278, 361",{},{"id":24,"text":1762,"url":24,"identifiers":1763},"Lagache, 1966, Cancer of the gastric stump following gastrectomy for ulcer, Arch. Chir., 20, 618",{},{"id":24,"text":1765,"url":24,"identifiers":1766},"Larson, 1961, Prognosis of the medically treated small gastric ulcer, New Engl. J. Med., 264, 330, 10.1056\u002FNEJM196102162640705",{"doi":1767},"10.1056\u002FNEJM196102162640705",{"id":24,"text":1769,"url":24,"identifiers":1770},"Pack, 1958, The late development of gastric cancer after gastroenterostomy and gastrectomy for peptic ulcer and benign pyloric stenosis, Surgery, 44, 1024",{},{"id":24,"text":1772,"url":24,"identifiers":1773},"Pygott, 1968, Gastric cancer associated with gastroenterostomy and partial gastrectorny, Gut, 9, 117, 10.1136\u002Fgut.9.1.117",{"doi":1774},"10.1136\u002Fgut.9.1.117",{"id":24,"text":1776,"url":24,"identifiers":1777},"Saegesser, 1972, Cancer of the gastric stump after partial gastrectomy (Billroth II principle) for ulcer, Cancer, 29, 1150, 10.1002\u002F1097-0142(197205)29:5\u003C1150::AID-CNCR2820290505>3.0.CO;2-5",{"doi":1778},"10.1002\u002F1097-0142(197205)29:5\u003C1150::AID-CNCR2820290505>3.0.CO;2-5",{"id":24,"text":1780,"url":24,"identifiers":1781},"Swynnerton, 1953, Chronic gastric ulcer—a comparison between a gastro-scopically controlled series treated medically, and a series treated by surgery, Br. Med. J., 2, 841, 10.1136\u002Fbmj.2.4841.841",{"doi":1782},"10.1136\u002Fbmj.2.4841.841",{"id":24,"text":1784,"url":24,"identifiers":1785},"Swynnerton, 1951, Simple gastric ulcer and carcinoma, Br. Med. J., 2, 1243, 10.1136\u002Fbmj.2.4742.1243",{"doi":1786},"10.1136\u002Fbmj.2.4742.1243",{"id":24,"text":1788,"url":24,"identifiers":1789},"Tanner, 1950, Techniques in British Surgery",{},{"id":24,"text":1791,"url":24,"identifiers":1792},"Tanner, 1951, Indications for surgery in peptic ulcer, Edinb. Med. J., 58, 261",{},{"id":24,"text":1794,"url":24,"identifiers":1795},"Tanner, 1952, Non-malignant affections of the upper stomach, Ann. R. Coll. Surg. Engl., 10, 45",{},{"id":24,"text":1797,"url":24,"identifiers":1798},"Tanner, 1966, Disabilities which may follow the peptic ulcer operation, Proc. R. Soc. Med., 59, 362",{},{"id":24,"text":1800,"url":24,"identifiers":1801},"Yanishevsky, 1968, Repeated operations for cancer in the residual stomach after gastric resection, Acta Med. Pol., 9, 421",{},{"id":1803,"createTime":1804,"updateTime":1805,"relativeEntities":1806,"slug":1807,"properties":1808,"entityType":107,"verifyStatus":108,"verifyTime":1804,"verifyNote":109,"languages":1826,"translateLanguages":1827,"viewCount":25,"primaryUrl":1828,"fullTextUrl":24,"authors":1829,"publicationType":147,"publisherRelationship":1942,"citationCount":1988,"citationInfo":1989,"publishDate":1992,"publishYear":1990,"citationAnalyzeStatus":23,"lastCitationAnalyze":1993,"indexDatabases":1994,"openAccess":24,"references":1995,"isForceReanalyzing":277},"5ed11131-4512-47cb-801e-4dea8d379fbe","2024-09-21T07:00:52.039+00:00","2026-05-05T01:46:29.577+00:00",[],"Caudate-lobe-sparing-subtotal-hepatectomy-for-primary-hepatolithiasis",{"mag":1809,"gsPaper":1811,"keywords":1813,"openalex":1814,"abstract":1816,"title":1819,"pm":1822,"doi":1824},{"VOID":1810},"2000554851",{"VOID":1812},"[\"15472269665988446386\"]",{"VI":469},{"VOID":1815},"W2000554851",{"VI":1817,"EN":1818},"\u003Cjats:title>Tóm tắt\u003C\u002Fjats:title>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Nền tảng\u003C\u002Fjats:title>\n                  \u003Cjats:p>Các bệnh nhân bị cơn tấn công viêm đường mật nguy hiểm đến tính mạng do sỏi gan nguyên phát hai bên với tình trạng teo gan chính và phình đại thùy đuôi đã được đánh giá để thực hiện cắt gan một phần bảo tồn thùy đuôi.\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Phương pháp\u003C\u002Fjats:title>\n                  \u003Cjats:p>Đây là một nghiên cứu hồi cứu dựa trên dữ liệu thu thập tiến hành từ trước của các bệnh nhân đã trải qua phẫu thuật cắt gan một phần bảo tồn thùy đuôi (cắt bỏ 7 phân khúc gan, chỉ để lại thùy đuôi) từ tháng 3 năm 2003 đến tháng 12 năm 2009. Tất cả bệnh nhân đã thực hiện kiểm tra đường mật đồng thời và soi đường mật. Các kết quả trong và sau phẫu thuật đã được phân tích.\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Kết quả\u003C\u002Fjats:title>\n                  \u003Cjats:p>Đã đạt được loại bỏ sỏi ngay lập tức ở cả 12 bệnh nhân tham gia nghiên cứu. Hai bệnh nhân đã trải qua phẫu thuật giãn mạch cho ống mật đuôi bị hẹp. Không có trường hợp tử vong tại bệnh viện và có sáu biến chứng xảy ra ở ba bệnh nhân. Tại thời điểm theo dõi trung bình là 51 tháng, một bệnh nhân đã bị sỏi tái phát ở ống mật thùy đuôi sau 8 tháng và chết do viêm đường mật purulent cấp tính, 17 tháng sau phẫu thuật. 11 bệnh nhân còn lại không có triệu chứng và không còn cơn tấn công viêm đường mật cấp tính nào khác.","\u003Cjats:title>Abstract\u003C\u002Fjats:title>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Background\u003C\u002Fjats:title>\n                  \u003Cjats:p>Patients with frequent and life-threatening attacks of cholangitis due to bilateral primary hepatolithiasis with atrophy of the main liver and giant hypertrophy of the caudate lobe were assessed for caudate lobe-sparing subtotal hepatectomy.\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Methods\u003C\u002Fjats:title>\n                  \u003Cjats:p>This was a retrospective study of prospectively collected data from patients who underwent subtotal hepatectomy with sparing of the caudate lobe (resection of 7 liver segments, leaving only the caudate lobe) between March 2003 and December 2009. All patients had concomitant bile duct exploration and choledochoscopy. Perioperative and long-term outcomes were analysed.\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Results\u003C\u002Fjats:title>\n                  \u003Cjats:p>Immediate stone clearance was obtained in all 12 patients enrolled in the study. Two patients had strictureplasty of the strictured caudate bile duct. There was no hospital mortality and six complications developed in three patients. At a mean follow-up of 51 months, one patient had developed recurrent stones in the caudate lobe bile ducts at 8 months and died from acute purulent cholangitis, 17 months after surgery. The remaining 11 patients were symptom-free with no further attacks of acute cholangitis.\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Conclusion\u003C\u002Fjats:title>\n                  \u003Cjats:p>In selected patients with bilateral primary hepatolithiasis, caudate lobe-sparing subtotal hepatectomy is a safe and effective treatment.\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>",{"EN":1820,"VI":1821},"Caudate lobe-sparing subtotal hepatectomy for primary hepatolithiasis","Cắt gan một phần bảo tồn thùy đuôi cho bệnh nhân sỏi gan nguyên phát",{"VOID":1823},"22961524",{"VOID":1825},"10.1002\u002Fbjs.8888",[111],[485],"https:\u002F\u002Facademic.oup.com\u002Fbjs\u002Farticle\u002F99\u002F10\u002F1423-1428\u002F6138690",[1830,1849,1876,1893,1908,1925],{"id":1831,"sortIndex":25,"researcher":24,"roles":1832,"affiliations":1833,"properties":1842,"displayName":1846,"givenName":24,"familyName":24},"f4fb8c38-5434-4a14-b915-83a75fc2e8f1",[],[1834],{"id":1835,"sortIndex":25,"affiliation":1836,"properties":24},"23ac221b-879f-48cd-8798-b21c1a160259",{"id":1835,"createTime":24,"updateTime":24,"relativeEntities":1837,"slug":24,"properties":1838,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1841,"statistic":24},[],{"title":1839},{"EN":1840},"Hospital and Institute of Hepatobiliary Surgery, Chinese People's Liberation Army General Hospital, Chinese PLA Postgraduate Medical School, Beijing, China.",[],{"orcid":1843,"title":1845,"openalex":1847},{"VOID":1844},"https:\u002F\u002Forcid.org\u002F0000-0001-7873-9364",{"EN":1846},"Jin‐Yong Dong",{"VOID":1848},"A5083730522",{"id":1850,"sortIndex":133,"researcher":24,"roles":1851,"affiliations":1852,"properties":1867,"displayName":1871,"givenName":24,"familyName":24},"a335e3e4-2948-4440-b703-486ff1609b7c",[],[1853,1861],{"id":1854,"sortIndex":25,"affiliation":1855,"properties":24},"9143ac06-b202-4ed2-8168-518fe36ca0ae",{"id":1854,"createTime":24,"updateTime":24,"relativeEntities":1856,"slug":24,"properties":1857,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1860,"statistic":24},[],{"title":1858},{"VI":1859},"Faculty of Medicine, the Chinese University of Hong Kong, Shatin, Hong Kong, China",[],{"id":1835,"sortIndex":133,"affiliation":1862,"properties":24},{"id":1835,"createTime":24,"updateTime":24,"relativeEntities":1863,"slug":24,"properties":1864,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1866,"statistic":24},[],{"title":1865},{"EN":1840},[],{"orcid":1868,"title":1870,"gsAuthor":1872,"openalex":1874},{"VOID":1869},"https:\u002F\u002Forcid.org\u002F0000-0002-6686-5440",{"EN":1871},"Wan Yee Lau",{"VOID":1873},"[\"llhWTl0AAAAJ\"]",{"VOID":1875},"A5053820568",{"id":1877,"sortIndex":334,"researcher":24,"roles":1878,"affiliations":1879,"properties":1886,"displayName":1890,"givenName":24,"familyName":24},"377c50a9-c609-4e73-8a32-74c35c7fec6f",[],[1880],{"id":1835,"sortIndex":25,"affiliation":1881,"properties":24},{"id":1835,"createTime":24,"updateTime":24,"relativeEntities":1882,"slug":24,"properties":1883,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1885,"statistic":24},[],{"title":1884},{"EN":1840},[],{"orcid":1887,"title":1889,"openalex":1891},{"VOID":1888},"https:\u002F\u002Forcid.org\u002F0000-0003-0127-3097",{"EN":1890},"Wei Lü",{"VOID":1892},"A5075588182",{"id":1894,"sortIndex":350,"researcher":24,"roles":1895,"affiliations":1896,"properties":1903,"displayName":1905,"givenName":24,"familyName":24},"ea0b74d9-5ac0-4a9e-b5dd-16bf880bd1a9",[],[1897],{"id":1835,"sortIndex":25,"affiliation":1898,"properties":24},{"id":1835,"createTime":24,"updateTime":24,"relativeEntities":1899,"slug":24,"properties":1900,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1902,"statistic":24},[],{"title":1901},{"EN":1840},[],{"title":1904,"openalex":1906},{"EN":1905},"W. 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2010, Hepatectomy for bilateral primary hepatolithiasis: a cohort study, Ann Surg, 251, 84, 10.1097\u002FSLA.0b013e3181b2f374",{"doi":1999},"10.1097\u002FSLA.0b013e3181b2f374",{"id":24,"text":2001,"url":24,"identifiers":2002},"Digby, 1930, Common-duct stones of liver origin, Br J Surg, 17, 578, 10.1002\u002Fbjs.1800176804",{"doi":2003},"10.1002\u002Fbjs.1800176804",{"id":24,"text":2005,"url":24,"identifiers":2006},"Cook, 1954, Recurrent pyogenic cholangitis, Br J Surg, 42, 188, 10.1002\u002Fbjs.18004217211",{"doi":2007},"10.1002\u002Fbjs.18004217211",{"id":24,"text":2009,"url":24,"identifiers":2010},"Lau, 2003, Surgical Management of Hepatobiliary and Pancreatic Disorders, 237",{},{"id":24,"text":2012,"url":24,"identifiers":2013},"Black, 2002, A scientist revisits the atrophy–hypertrophy complex: hepatic apoptosis and regeneration, Surg Oncol Clin N Am, 11, 849, 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384",{},{"id":24,"text":2033,"url":24,"identifiers":2034},"Murakami, 2002, Human liver caudate lobe and liver segment, Anat Sci Int, 77, 211, 10.1046\u002Fj.0022-7722.2002.00033.x",{"doi":2035},"10.1046\u002Fj.0022-7722.2002.00033.x",{"id":24,"text":2037,"url":24,"identifiers":2038},"Watanabe, 1999, Assessment of hepatic functional reserve in cirrhotic patients by computed tomography of the caudate lobe, Dig Dis Sci, 44, 2554, 10.1023\u002FA:1026663811723",{"doi":2039},"10.1023\u002FA:1026663811723",{"id":24,"text":2041,"url":24,"identifiers":2042},"Boozari, 2008, Ultrasonography in patients with Budd–Chiari syndrome: diagnostic signs and prognostic implications, J Hepatol, 49, 572, 10.1016\u002Fj.jhep.2008.04.025",{"doi":2043},"10.1016\u002Fj.jhep.2008.04.025",{"id":24,"text":2045,"url":24,"identifiers":2046},"Düşünceli, 2005, Primary sclerosing cholangitis: MR cholangiopancreatography and T2-weighted MR imaging findings, Diagn Interv Radiol, 11, 213",{},{"id":24,"text":2048,"url":24,"identifiers":2049},"Zhou, 2007, Liver volume variation in patients with virus-induced cirrhosis: findings on MDCT, AJR Am J Roentgenol, 189, W153, 10.2214\u002FAJR.07.2181",{"doi":2050},"10.2214\u002FAJR.07.2181",{"id":2052,"createTime":2053,"updateTime":2054,"relativeEntities":2055,"slug":2056,"properties":2057,"entityType":107,"verifyStatus":108,"verifyTime":2053,"verifyNote":109,"languages":2072,"translateLanguages":24,"viewCount":25,"primaryUrl":2073,"fullTextUrl":24,"authors":2074,"publicationType":147,"publisherRelationship":2122,"citationCount":25,"citationInfo":2167,"publishDate":2170,"publishYear":2168,"citationAnalyzeStatus":23,"lastCitationAnalyze":2054,"indexDatabases":2171,"openAccess":24,"references":2172,"isForceReanalyzing":277},"4d71074d-baff-482f-80a7-f979857b9a1b","2024-10-15T22:57:30.857+00:00","2026-04-15T03:49:10.673+00:00",[],"Cell-viability-studies-on-the-exfoliated-colonic-cancer-cell",{"mag":2058,"gsPaper":2060,"openalex":2062,"abstract":2064,"title":2066,"pm":2068,"doi":2070},{"VOID":2059},"1968468781",{"VOID":2061},"[\"13004814224104469660\"]",{"VOID":2063},"W1968468781",{"EN":2065},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\n               \u003Cjats:p>Suspensions of desquamated colonic cancer cells were obtained from patients with cancer of the large bowel by colonic exfoliative cytology and from resected specimens of colonic cancer by an ex vivo exfoliation technique. In addition, a tumour suspension was obtained from the resected specimens. Cell viability studies were performed on these cell suspensions. Whereas 23 of the 25 tumour homogenate cell suspensions were shown to exclude trypan blue, none of the exfoliated colonic cancer cell suspensions had viable cells. This finding would cast some doubt on the hypothesis that suture line recurrence following large bowel cancer surgery is due to the implantation of cells desquamated from the surface of the growth.\u003C\u002Fjats:p>",{"EN":2067},"Cell viability studies on the exfoliated colonic cancer cell",{"VOID":2069},"638432",{"VOID":2071},"10.1002\u002Fbjs.1800650314",[111],"https:\u002F\u002Facademic.oup.com\u002Fbjs\u002Farticle\u002F65\u002F3\u002F188\u002F6192972",[2075,2092,2107],{"id":2076,"sortIndex":25,"researcher":24,"roles":2077,"affiliations":2078,"properties":2087,"displayName":2089,"givenName":24,"familyName":24},"39f1b174-390a-424f-b9db-7a23e7519862",[],[2079],{"id":2080,"sortIndex":25,"affiliation":2081,"properties":24},"3080b031-8414-4131-b8dd-85cfe9222a94",{"id":2080,"createTime":24,"updateTime":24,"relativeEntities":2082,"slug":24,"properties":2083,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":2086,"statistic":24},[],{"title":2084},{"EN":2085},"University Department of Surgery, St James's University Hospital, Leeds",[],{"title":2088,"openalex":2090},{"EN":2089},"I L Rosenberg",{"VOID":2091},"A5052646957",{"id":2093,"sortIndex":133,"researcher":24,"roles":2094,"affiliations":2095,"properties":2102,"displayName":2104,"givenName":24,"familyName":24},"b73e3b50-b66c-4b53-9ef0-7eee53b6056a",[],[2096],{"id":2080,"sortIndex":25,"affiliation":2097,"properties":24},{"id":2080,"createTime":24,"updateTime":24,"relativeEntities":2098,"slug":24,"properties":2099,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":2101,"statistic":24},[],{"title":2100},{"EN":2085},[],{"title":2103,"openalex":2105},{"EN":2104},"Carol W Russell",{"VOID":2106},"A5021977329",{"id":2108,"sortIndex":334,"researcher":24,"roles":2109,"affiliations":2110,"properties":2117,"displayName":2119,"givenName":24,"familyName":24},"ecf817d0-7495-4c1d-a667-7ad4690dc7fe",[],[2111],{"id":2080,"sortIndex":25,"affiliation":2112,"properties":24},{"id":2080,"createTime":24,"updateTime":24,"relativeEntities":2113,"slug":24,"properties":2114,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":2116,"statistic":24},[],{"title":2115},{"EN":2085},[],{"title":2118,"openalex":2120},{"EN":2119},"G R Giles",{"VOID":2121},"A5105125082",{"url":24,"publisher":2123,"properties":2161},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":2124,"slug":10,"properties":2125,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":2130,"manageAffiliations":2135,"indexDatabases":2146,"url":83,"thumbnailPath":24,"statistic":24,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":2126,"eissn":2127,"issn":2128,"title":2129},{"VOID":13},{"VOID":15},{"VOID":17},{"EN":19},[2131],{"id":28,"createTime":24,"updateTime":24,"relativeEntities":2132,"label":2133,"description":2134,"parentId":24,"standard":24,"scholarHubFieldId":24},[],{"EN":31},{},[2136,2141],{"id":35,"createTime":24,"updateTime":24,"relativeEntities":2137,"slug":24,"properties":2138,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":2140,"statistic":24},[],{"title":2139},{"EN":39},[],{"id":42,"createTime":24,"updateTime":24,"relativeEntities":2142,"slug":24,"properties":2143,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":2145,"statistic":24},[],{"title":2144},{"EN":46},[],[2147,2154],{"id":50,"indexDatabase":2148,"url":63,"indexYears":24,"academicFieldIds":2153,"indexDatabaseRanking":24},{"id":52,"createTime":24,"updateTime":24,"relativeEntities":2149,"label":2150,"description":2151,"key":59,"publicationTags":2152,"standard":24},[],{"EN":55,"VI":55},{"EN":57,"VI":58},[61,62],[65],{"id":67,"indexDatabase":2155,"url":78,"indexYears":79,"academicFieldIds":2160,"indexDatabaseRanking":82},{"id":69,"createTime":24,"updateTime":24,"relativeEntities":2156,"label":2157,"description":2158,"key":75,"publicationTags":2159,"standard":24},[],{"EN":72,"VI":72},{"EN":72,"VI":74},[77],[81],{"issue":2162,"pages":2163,"volume":2165},{"VOID":1717},{"VOID":2164},"188-190",{"VOID":2166},"65",{"total":25,"publishYear":2168,"statisticByYear":2169},1978,{},"1978-03-01",[61,82],[2173,2176,2179,2182,2186,2189,2193,2197,2201,2205,2209,2212,2216,2219,2223,2227,2230,2234],{"id":24,"text":2174,"url":24,"identifiers":2175},"Child, 1972, DNA synthesizing cells in cervical scrapings; a potential but presently unusable approach to pre-screening, Acta Cytol., 16, 37",{},{"id":24,"text":2177,"url":24,"identifiers":2178},"Cole, 1951, Measures to combat the menace of cancer, Am. Surg., 17, 660",{},{"id":24,"text":2180,"url":24,"identifiers":2181},"Connolly, 1964, In vitro labelling and autoradiography of exfoliated cells in carcinoma of the human bladder, Surg. Forum, 15, 489",{},{"id":24,"text":2183,"url":24,"identifiers":2184},"Cooper, 1975, Cell death in normal and malignant tissues, Adv. Cancer Res., 21, 59, 10.1016\u002FS0065-230X(08)60971-9",{"doi":2185},"10.1016\u002FS0065-230X(08)60971-9",{"id":24,"text":2187,"url":24,"identifiers":2188},"Deschner, 1973, Autoradiographic method for an expanded assessment of colonic cytology, Cytologica, 17, 435",{},{"id":24,"text":2190,"url":24,"identifiers":2191},"Goligher, 1951, Local recurrence after sphincter-saving excisions for carcinoma of the rectum and rectosigmoid, Br. J. Surg., 39, 199, 10.1002\u002Fbjs.18003915504",{"doi":2192},"10.1002\u002Fbjs.18003915504",{"id":24,"text":2194,"url":24,"identifiers":2195},"Gordon-Watson, 1938, Origin and spread of cancer of the rectum, Lancet, 1, 239, 10.1016\u002FS0140-6736(00)93564-5",{"doi":2196},"10.1016\u002FS0140-6736(00)93564-5",{"id":24,"text":2198,"url":24,"identifiers":2199},"Hofer, 1974, Viability of tumour cells in mechanically and enzymatically prepared tissue suspensions, Eur. J. Cancer, 10, 49, 10.1016\u002F0014-2964(74)90037-1",{"doi":2200},"10.1016\u002F0014-2964(74)90037-1",{"id":24,"text":2202,"url":24,"identifiers":2203},"Hoskins, 1956, A comparison of methods for estimating the viable count of a suspension of tumour cells, Exp. Cell Res., 11, 297, 10.1016\u002F0014-4827(56)90105-7",{"doi":2204},"10.1016\u002F0014-4827(56)90105-7",{"id":24,"text":2206,"url":24,"identifiers":2207},"Keynes, 1961, Implantation from the bowel lumen in cancer of the large intestine, Ann. Surg., 153, 357, 10.1097\u002F00000658-196103000-00003",{"doi":2208},"10.1097\u002F00000658-196103000-00003",{"id":24,"text":2210,"url":24,"identifiers":2211},"King, 1959, Cell death IV: the effect of injury on the entrance of vital dye in Ehrlich tumour cells, Am. J. Pathol., 35, 1067",{},{"id":24,"text":2213,"url":24,"identifiers":2214},"Labow, 1975, Suture line recurrence in carcinoma of the colon and rectum, Dis. Colon Rectum, 18, 123, 10.1007\u002FBF02587157",{"doi":2215},"10.1007\u002FBF02587157",{"id":24,"text":2217,"url":24,"identifiers":2218},"Morgan, 1955, Trends in the treatment of tumours of the rectum, rectosigmoid and left colon, J. R. Coll. Surg. Edinb., 1, 112",{},{"id":24,"text":2220,"url":24,"identifiers":2221},"Rosenberg, 1977, The value of colonic exfoliative cytology in the diagnosis of carcinoma of the large bowel, Dis. Colon Rectum, 20, 1, 10.1007\u002FBF02587444",{"doi":2222},"10.1007\u002FBF02587444",{"id":24,"text":2224,"url":24,"identifiers":2225},"Southwick, 1962, Recurrence at the suture line following resection for carcinoma of the colon. Incidence following preventive measures, Am. J. Surg., 103, 86, 10.1016\u002F0002-9610(62)90020-X",{"doi":2226},"10.1016\u002F0002-9610(62)90020-X",{"id":24,"text":2228,"url":24,"identifiers":2229},"Speck, 1970, Analysis of 860 patients with carcinoma of the transverse and descending colon, Surg. Gynecol. Obstet., 130, 259",{},{"id":24,"text":2231,"url":24,"identifiers":2232},"Straus, 1948, Demonstration of reducing enzyme systems in neoplasms and living mammalian tissues by triphenyltetrazolium chloride, Science, 108, 113, 10.1126\u002Fscience.108.2796.113",{"doi":2233},"10.1126\u002Fscience.108.2796.113",{"id":24,"text":2235,"url":24,"identifiers":2236},"Wachstein, 1958, The histochemical demonstration of esterasc activity in human blood and bone marrow smears, J. Histochem. Cytochem., 6, 457, 10.1177\u002F6.6.457",{"doi":2237},"10.1177\u002F6.6.457"]