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Đánh giá kinh tế này nhằm định lượng hiệu quả chi phí của can thiệp mHealth này từ góc độ nhà cung cấp dịch vụ y tế và xã hội.\n\nPhương pháp và phân tích Thử nghiệm V-SMART sẽ tuyển dụng 902 bệnh nhân điều trị lao MDR-TB tại bảy tỉnh tham gia ở Việt Nam. Các tham gia viên trong cả nhóm can thiệp và nhóm đối chứng sẽ nhận được liệu pháp chuẩn dựa vào cộng đồng cho lao MDR-TB. Các tham gia viên trong nhóm can thiệp cũng sẽ có một ứng dụng được thiết kế riêng cài đặt trên smartphone của họ để báo cáo các AE cho nhân viên y tế và tạo điều kiện quản lý kịp thời các AE. Đánh giá kinh tế này sẽ so sánh chi phí và kết quả sức khoẻ giữa nhóm can thiệp (mHealth) và nhóm đối chứng (chuẩn điều trị). Chi phí liên quan đến việc thực hiện can thiệp và sử dụng dịch vụ y tế sẽ được ghi lại, cũng như chi phí tự chi trả của bệnh nhân. Chất lượng cuộc sống liên quan đến sức khỏe (HRQoL) của các tham gia viên nghiên cứu sẽ được ghi nhận bằng bảng hỏi 36 mục (SF-36) và được sử dụng để tính toán năm điều chỉnh theo chất lượng (QALYs). Tỷ lệ hiệu quả chi phí gia tăng (ICERs) sẽ được dựa trên kết quả chính (tỷ lệ bệnh nhân thành công điều trị sau 24 tháng) và QALYs đã đạt được. Phân tích nhạy cảm sẽ được thực hiện để kiểm tra tính ổn định của các ICERs. Một phân tích tác động ngân sách sẽ được thực hiện từ góc độ người chi trả để cung cấp một ước lượng về tổng ngân sách cần thiết để mở rộng việc thực hiện can thiệp.\n\nĐạo đức và phổ biến Phê duyệt đạo đức cho nghiên cứu đã được cấp bởi Ủy ban Đạo đức Nghiên cứu Con người Đại học Sydney (2019\u002F676), Ủy ban Khoa học của Bộ Khoa học và Công nghệ, Việt Nam (08\u002FQD-HDQL-NAFOSTED) và Hội đồng Đánh giá Đạo đức Bệnh viện Phổi Quốc gia, Việt Nam (13\u002F19\u002FCT-HDDD). Các kết quả nghiên cứu sẽ được công bố trên các tạp chí có phản biện và tài liệu hội nghị.","Introduction The Strengthen the Management of Multidrug-Resistant Tuberculosis in Vietnam (V-SMART) trial is a randomised controlled trial of using mobile health (mHealth) technologies to improve adherence to medications and management of adverse events (AEs) in people with multidrug-resistant tuberculosis (MDR-TB) undergoing treatment in Vietnam. This economic evaluation seeks to quantify the cost-effectiveness of this mHealth intervention from a healthcare provider and societal perspective.\n\nMethods and analysis The V-SMART trial will recruit 902 patients treated for MDR-TB across seven participating provinces in Vietnam. Participants in both intervention and control groups will receive standard community-based therapy for MDR-TB. Participants in the intervention group will also have a purpose-designed App installed on their smartphones to report AEs to health workers and to facilitate timely management of AEs. This economic evaluation will compare the costs and health outcomes between the intervention group (mHealth) and the control group (standard of care). Costs associated with delivering the intervention and health service utilisation will be recorded, as well as patient out-of-pocket costs. The health-related quality of life (HRQoL) of study participants will be captured using the 36-Item Short Form Survey (SF-36) questionnaire and used to calculate quality-adjusted life-years (QALYs). Incremental cost-effectiveness ratios (ICERs) will be based on the primary outcome (proportion of patients with treatment success after 24 months) and QALYs gained. Sensitivity analysis will be conducted to test the robustness of the ICERs. A budget impact analysis will be conducted from a payer perspective to provide an estimate of the total budget required to scale-up delivery of the intervention.\n\nEthics and dissemination Ethical approval for the study was granted by the University of Sydney Human Research Ethics Committee (2019\u002F676), the Scientific Committee of the Ministry of Science and Technology, Vietnam (08\u002FQD-HDQL-NAFOSTED) and the Institutional Review Board of the National Lung Hospital, Vietnam (13\u002F19\u002FCT-HDDD). 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Recent studies have found differences between countries in terms of health values or preferences for health states described by instruments such as the EQ-5D. The project aims to model a national value set for the five level version of the EQ-5D based on values elicited from a representative sample of the Norwegian adult general population in terms of region, age, sex and level of education. Using a sampling strategy supporting the collection of values for both hypothetical and experienced health states, the study will have the additional aim of assessing the feasibility of collecting experience-based values in accordance with the latest EQ-5D valuation study protocol, and comparing values with those given for hypothetical health states.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Methods and analysis\u003C\u002Fjats:title>\u003Cjats:p>Multistage random sampling and quota-sampling will contribute to representativeness. To increase the number of valuations of experienced health states, those with less than perfect health will be oversampled, increasing the total number of interviews from 1000 to 1300–1500. The most recent EQ-5D valuation protocol will be followed which includes computer assisted face-to-face, one-to-one interviews and use of composite time trade-off and discrete choice experiments.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Ethics and dissemination\u003C\u002Fjats:title>\u003Cjats:p>The study has been reviewed and found to be outside of the scope of the ethics committee and thus not in need of ethical approval. The study findings will be disseminated through peer-reviewed publications, conference presentations and summaries for key stakeholders and partners in the field. 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Available: https:\u002F\u002Fmicrodata.no\u002Fen\u002F",{},{"id":23,"text":970,"url":23,"identifiers":971},"Purba, 2017, Employing quality control and feedback to the EQ-5D-5L valuation protocol to improve the quality of data collection, Qual Life Res, 26, 1197, 10.1007\u002Fs11136-016-1445-9",{"doi":972},"10.1007\u002Fs11136-016-1445-9",{"id":23,"text":974,"url":23,"identifiers":975},"Ramos-Goñi, 2017, Quality control process for EQ-5D-5L valuation studies, Value Health, 20, 466, 10.1016\u002Fj.jval.2016.10.012",{"doi":976},"10.1016\u002Fj.jval.2016.10.012",{"id":23,"text":978,"url":23,"identifiers":979},"Stolk, 2019, Overview, update, and lessons learned from the International EQ-5D-5L valuation work: version 2 of the EQ-5D-5L valuation protocol, Value Health, 22, 23, 10.1016\u002Fj.jval.2018.05.010",{"doi":980},"10.1016\u002Fj.jval.2018.05.010",{"id":23,"text":982,"url":23,"identifiers":983},"van Nooten, 2018, What should we know about the person behind a TTO?, Eur J Health Econ, 19, 1207, 10.1007\u002Fs10198-018-0975-1",{"doi":984},"10.1007\u002Fs10198-018-0975-1",{"id":23,"text":986,"url":23,"identifiers":987},"10.1097\u002FMLR.0000000000000066",{"doi":986},{"id":23,"text":989,"url":23,"identifiers":990},"10.1177\u002F0272989X07302127",{"doi":989},{"id":23,"text":992,"url":23,"identifiers":993},"van Nooten, 2015, \"Married with children\" the influence of significant others in TTO exercises, Health Qual Life Outcomes, 13, 10.1186\u002Fs12955-015-0276-7",{"doi":994},"10.1186\u002Fs12955-015-0276-7",{"id":23,"text":996,"url":23,"identifiers":997},"Helgesson G , Ernstsson O , Åström M , et al . Whom should we ask? A systematic literature review of the arguments regarding the most accurate source of information for valuation of health states. Qual Life Res 2020;4.doi:10.1007\u002Fs11136-020-02426-4",{"doi":998},"10.1007\u002Fs11136-020-02426-4",{"id":1000,"createTime":1001,"updateTime":1002,"relativeEntities":1003,"slug":1004,"properties":1005,"entityType":137,"verifyStatus":138,"verifyTime":1018,"verifyNote":139,"languages":1019,"translateLanguages":1020,"viewCount":24,"primaryUrl":1021,"fullTextUrl":1022,"authors":1023,"publicationType":439,"publisherRelationship":1909,"citationCount":24,"citationInfo":1953,"publishDate":1955,"publishYear":778,"citationAnalyzeStatus":22,"lastCitationAnalyze":1002,"indexDatabases":1956,"openAccess":23,"references":1957,"isForceReanalyzing":582},"7fb92f24-9873-4131-95d9-655ba1f0286f","2024-12-25T18:35:14.970+00:00","2026-07-11T09:49:00.851+00:00",[],"Impacts-and-interactions-of-COVID-19-response-involvement-health-related-behaviours-health-literacy-on-anxiety-depression-and-health-related-quality-of-life-among-healthcare-workers-a-cross-sectional-study",{"abstract":1006,"title":1009,"gsPaper":1012,"keywords":1014,"doi":1016},{"VI":1007,"EN":1008},"Mục tiêu: Chúng tôi đã nghiên cứu tác động và tương tác của việc tham gia vào công tác ứng phó COVID-19, các hành vi liên quan đến sức khỏe và sức khỏe kém (HL) đối với lo âu, trầm cảm và chất lượng cuộc sống liên quan đến sức khỏe (HRQoL) ở nhân viên y tế (HCWs). \n\nThiết kế: Một nghiên cứu cắt ngang đã được tiến hành. Dữ liệu được thu thập từ ngày 6 đến 19 tháng 4 năm 2020 bằng cách sử dụng bảng hỏi tự quản được thực hiện trực tuyến. \n\nĐịa điểm: 19 bệnh viện và trung tâm y tế tại Việt Nam. \n\nNgười tham gia: 7.124 nhân viên y tế trong độ tuổi từ 21 đến 60. \n\nKết quả: Nhân viên y tế tham gia vào công tác ứng phó COVID-19 có khả năng lo âu cao hơn (OR (95% CI)=4.41 (3.53 đến 5.51)), khả năng trầm cảm cao hơn (OR(95% CI)=3.31 (2.71 đến 4.05)) và điểm số HRQoL thấp hơn (hệ số, b(95% CI)=−2.14 (−2.89 đến −1.38)) so với nhân viên y tế không tham gia. Tổng thể, nhân viên y tế có hút thuốc hoặc uống rượu với mức độ không thay đổi\u002Ftăng có khả năng lo âu, trầm cảm cao hơn và điểm HRQoL thấp hơn; những người có chế độ ăn không thay đổi\u002Fkhỏe mạnh, hoạt động thể chất không thay đổi\u002Fnhiều hơn và điểm HL cao hơn có khả năng lo âu, trầm cảm thấp hơn và điểm HRQoL cao hơn. So với nhân viên y tế không tham gia có hút thuốc hoặc uống rượu ở mức không bao giờ\u002Fdừng lại\u002Fgiảm mức, nhân viên y tế tham gia với mức độ hút thuốc hoặc uống rượu không thay đổi\u002Ftăng có khả năng lo âu thấp hơn (OR(95% CI)=0.34 (0.14 đến 0.83)) hoặc (OR(95% CI)=0.26 (0.11 đến 0.60)), và khả năng trầm cảm thấp hơn (OR(95% CI)=0.33 (0.15 đến 0.74)) hoặc (OR(95% CI)=0.24 (0.11 đến 0.53)), tương ứng. So với nhân viên y tế không tham gia có tập thể dục ở mức không bao giờ\u002Fdừng lại\u002Fgiảm mức, hoặc với những người ở tứ phân vị HL thấp nhất, nhân viên y tế tham gia với hoạt động thể chất không thay đổi\u002Ftăng hoặc với sự gia tăng một tứ phân vị HL báo cáo khả năng lo âu thấp hơn (OR(95% CI)=0.50 (0.31 đến 0.81)) hoặc (OR(95% CI)=0.57 (0.45 đến 0.71)), khả năng trầm cảm thấp hơn (OR(95% CI)=0.40 (0.27 đến 0.61)) hoặc (OR(95% CI)=0.63 (0.52 đến 0.76)), và điểm HRQoL cao hơn (b(95% CI)=2.08 (0.58 đến 3.58)), hoặc (b(95% CI)=1.10 (0.42 đến 1.78)), tương ứng. \n\nKết luận: Hoạt động thể chất và HL cao hơn được phát hiện có tác dụng bảo vệ chống lại lo âu và trầm cảm và liên quan đến HRQoL cao hơn. Một cách bất ngờ, hút thuốc và uống rượu cũng được tìm thấy là những hành vi đối phó. Quan trọng là cần có các phương pháp tiếp cận chiến lược nhằm bảo vệ sức khỏe tâm thần và HRQoL của nhân viên y tế.","Objectives We examined impacts and interactions of COVID-19 response involvement, health-related behaviours and health literacy (HL) on anxiety, depression, and health-related quality of life (HRQoL) among healthcare workers (HCWs).\n\nDesign A cross-sectional study was conducted. Data were collected 6 April to 19 April 2020 using online-based, self-administered questionnaires.\n\nSetting 19 hospitals and health centres in Vietnam.\n\nParticipants 7 124 HCWs aged 21–60 years.\n\nResults The COVID-19 response-involved HCWs had higher anxiety likelihood (OR (95% CI)=4.41 (3.53 to 5.51)), higher depression likelihood (OR(95% CI)=3.31 (2.71 to 4.05)) and lower HRQoL score (coefficient, b(95% CI)=−2.14 (−2.89 to −1.38)), compared with uninvolved HCWs. Overall, HCWs who smoked or drank at unchanged\u002Fincreased levels had higher likelihood of anxiety, depression and lower HRQoL scores; those with unchanged\u002Fhealthier eating, unchanged\u002Fmore physical activity and higher HL scores had lower likelihood of anxiety, depression and higher HRQoL scores. In comparison to uninvolved HCWs who smoked or drank at never\u002Fstopped\u002Freduced levels, involved HCWs with unchanged\u002Fincreased smoking or drinking had lower anxiety likelihood (OR(95% CI)=0.34 (0.14 to 0.83)) or (OR(95% CI)=0.26 (0.11 to 0.60)), and lower depression likelihood (OR(95% CI)=0.33 (0.15 to 0.74)) or (OR(95% CI)=0.24 (0.11 to 0.53)), respectively. In comparison with uninvolved HCWs who exercised at never\u002Fstopped\u002Freduced levels, or with those in the lowest HL quartile, involved HCWs with unchanged\u002Fincreased exercise or with one-quartile HL increment reported lower anxiety likelihood (OR(95% CI)=0.50 (0.31 to 0.81)) or (OR(95% CI)=0.57 (0.45 to 0.71)), lower depression likelihood (OR(95% CI)=0.40 (0.27 to 0.61)) or (OR(95% CI)=0.63 (0.52 to 0.76)), and higher HRQoL scores (b(95% CI)=2.08 (0.58 to 3.58)), or (b(95% CI)=1.10 (0.42 to 1.78)), respectively.\n\nConclusions Physical activity and higher HL were found to protect against anxiety and depression and were associated with higher HRQoL. Unexpectedly, smoking and drinking were also found to be coping behaviours. It is important to have strategic approaches that protect HCWs’ mental health and HRQoL.",{"EN":1010,"VI":1011},"Impacts and interactions of COVID-19 response involvement, health-related behaviours, health literacy on anxiety, depression and health-related quality of life among healthcare workers: a cross-sectional study","Tác động và tương tác của việc tham gia vào đáp ứng COVID-19, hành vi liên quan đến sức khỏe, và sức khỏe tâm thần đến lo âu, trầm cảm và chất lượng cuộc sống liên quan đến sức khỏe trong số nhân viên y tế: một nghiên cứu cắt ngang",{"VOID":1013},"[\"1191382603640874244\"]",{"VI":1015},"COVID-19, nhân viên y tế, lo âu, trầm cảm, chất lượng cuộc sống liên quan đến sức khỏe, sức khỏe kém, hoạt động thể chất, sức khỏe tâm 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Chen;citation_title=Depressive symptoms as a predictor of sexual function during pregnancy.;citation_pages=2582-2589;citation_volume=9;citation_year=2012;citation_issue=10;citation_pmid=22897117",{"id":2162,"createTime":2163,"updateTime":2164,"relativeEntities":2165,"slug":2166,"properties":2167,"entityType":137,"verifyStatus":138,"verifyTime":2182,"verifyNote":139,"languages":23,"translateLanguages":2183,"viewCount":24,"primaryUrl":2184,"fullTextUrl":2185,"authors":2186,"publicationType":439,"publisherRelationship":2534,"citationCount":331,"citationInfo":2578,"publishDate":2581,"publishYear":2579,"citationAnalyzeStatus":22,"lastCitationAnalyze":2582,"indexDatabases":2583,"openAccess":23,"references":23,"isForceReanalyzing":582},"ec1cf4ff-3f89-4212-978f-94d8182eeb1d","2024-01-23T16:05:48.778+00:00","2026-03-28T00:45:05.288+00:00",[],"Harnessing-new-mHealth-technologies-to-Strengthen-the-Management-of-Multidrug-Resistant-Tuberculosis-in-Vietnam-V-SMART-trial-a-protocol-for-a-randomised-controlled-trial",{"abstract":2168,"title":2171,"gsPaper":2174,"keywords":2176,"references":2178,"doi":2180},{"VI":2169,"EN":2170},"Giới thiệu Lao kháng đa thuốc (MDR-TB) vẫn là một vấn đề sức khỏe cộng đồng lớn toàn cầu. Các phác đồ điều trị dài và phức tạp, kết hợp với các sự kiện bất lợi thường xuyên, đã dẫn đến việc tuân thủ điều trị kém và kết quả điều trị không tốt. Các công nghệ sức khỏe di động (mHealth) dựa trên smartphone cung cấp cho các chương trình lao quốc gia một nền tảng hấp dẫn để cải thiện chăm sóc và quản lý bệnh nhân; tuy nhiên, bằng chứng từ các nghiên cứu lâm sàng để hỗ trợ việc sử dụng chúng còn thiếu. Thử nghiệm này sẽ kiểm tra giả thuyết rằng một can thiệp mHealth có thể cải thiện tỷ lệ thành công trong điều trị ở những bệnh nhân mắc MDR-TB và có hiệu quả chi phí so với thực hành tiêu chuẩn.\n\nPhương pháp và phân tích Một thử nghiệm ngẫu nhiên có đối chứng, mù mở, nhóm song song sẽ được thực hiện trên những bệnh nhân được điều trị lao MDR-TB tại bảy tỉnh của Việt Nam. Những bệnh nhân bắt đầu điều trị cho lao kháng rifampicin hoặc lao kháng đa thuốc đã được xác nhận vi sinh học trong vòng 30 ngày qua sẽ được tuyển chọn vào nghiên cứu. Các tham gia sẽ được ngẫu nhiên hóa vào một nhóm can thiệp, bao gồm việc sử dụng một ứng dụng mHealth để hỗ trợ điều trị, hoặc một nhóm 'chăm sóc tiêu chuẩn'. Trong cả hai nhóm, bệnh nhân sẽ được quản lý bởi chương trình lao quốc gia theo các hướng dẫn điều trị quốc gia hiện hành. Biện pháp kết quả chính của hiệu quả sẽ là tỷ lệ bệnh nhân thành công trong điều trị (được định nghĩa là hoàn thành điều trị và\u002Fhoặc chữa khỏi vi sinh) sau 24 tháng. Một mô hình hồi quy Poisson biên giới được ước tính thông qua một phương pháp ước lượng tổng quát sẽ được sử dụng để kiểm tra tác động của can thiệp lên thành công điều trị. Một phân tích chi phí hiệu quả theo kiểu microcosting và phân tích hiệu quả chi phí trong thử nghiệm cũng sẽ được thực hiện từ góc độ xã hội. Hiệu quả chi phí sẽ được trình bày dưới dạng chi phí gia tăng cho mỗi bệnh nhân được điều trị thành công và chi phí gia tăng cho mỗi năm sống điều chỉnh theo chất lượng nhận được.\n\nĐạo đức Sự chấp thuận đạo đức cho nghiên cứu đã được cấp bởi Ủy ban Đạo đức Nghiên cứu Nhân học của Đại học Sydney (2019\u002F676).\n\nPhát tán Các phát hiện của nghiên cứu sẽ được phát tán đến các tham gia và được công bố trong các tạp chí đánh peer và tài liệu hội nghị.","Introduction Multidrug-resistant tuberculosis (MDR-TB) remains a major public health problem globally. Long, complex treatment regimens coupled with frequent adverse events have resulted in poor treatment adherence and patient outcomes. Smartphone-based mobile health (mHealth) technologies offer national TB programmes an appealing platform to improve patient care and management; however, clinical trial evidence to support their use is lacking. This trial will test the hypothesis that an mHealth intervention can improve treatment success among patients with MDR-TB and is cost-effective compared with standard practice.\n\nMethods and analysis A community-based, open-label, parallel-group randomised controlled trial will be conducted among patients treated for MDR-TB in seven provinces of Vietnam. Patients commencing therapy for microbiologically confirmed rifampicin-resistant or multidrug-resistant tuberculosis within the past 30 days will be recruited to the study. Participants will be individually randomised to an intervention arm, comprising use of an mHealth application for treatment support, or a ‘standard care’ arm. In both arms, patients will be managed by the national TB programme according to current national treatment guidelines. The primary outcome measure of effectiveness will be the proportion of patients with treatment success (defined as treatment completion and\u002For bacteriological cure) after 24 months. A marginal Poisson regression model estimated via a generalised estimating equation will be used to test the effect of the intervention on treatment success. A prospective microcosting of the intervention and within-trial cost-effectiveness analysis will also be undertaken from a societal perspective. Cost-effectiveness will be presented as an incremental cost per patient successfully treated and an incremental cost per quality-adjusted life-year gained.\n\nEthics Ethical approval for the study was granted by The University of Sydney Human Research Ethics Committee (2019\u002F676).\n\nDissemination Study findings will be disseminated to participants and published in peer-reviewed journals and conference proceedings.\n\nTrial registration number ACTRN12620000681954.",{"EN":2172,"VI":2173},"Harnessing new mHealth technologies to Strengthen the Management of Multidrug-Resistant Tuberculosis in Vietnam (V-SMART trial): a protocol for a randomised controlled trial","Tận dụng công nghệ mHealth mới để Tăng cường Quản lý Bệnh Lao Kháng Đa thuốc tại Việt Nam (thử nghiệm V-SMART): một giao thức cho thử nghiệm ngẫu nhiên có đối chứng",{"VOID":2175},"3915022138325154397",{"VI":2177},"MDR-TB, mHealth, nghiên cứu lâm sàng, quản lý bệnh lao, hiệu quả chi phí",{"VOID":2179},"citation_title=Stop TB Initiative & Ministerial Conference on Tuberculosis and Sustainable Developmen: The Economic impacts of tuberculosis;citation_year=2000\ncitation_journal_title=PLoS One;citation_author=K. 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Better understanding of avoidable incidents is needed to prevent them and the associated ED presentations in community-dwelling adults. This study aimed to synthetise the actual knowledge concerning these incidents leading this population to ED presentation, as well as possible preventive measures to reduce them.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Design\u003C\u002Fjats:title>\u003Cjats:p>A scoping review was performed according to the Arksey and O’Malley framework.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Methods\u003C\u002Fjats:title>\u003Cjats:p>Scientific and grey literature published between 1996 and 2017 were examined in databases (Medline, Cumulative Index of Nursing and Allied Health, Ageline, Scopus, ProQuest Dissertations\u002Ftheses, Evidence-based medecine (EBM) Reviews, Healthstar), online library catalogues, governmental websites and published statistics. Sources discussing avoidable incidents leading to ED presentations were included and then extended to those discussing hospitalisation and mortality due to a lack of sources. Data (type, frequency, severity and circumstances of incidents, preventive measures) was extracted using a thematic chart, then analysed with content analysis.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Results\u003C\u002Fjats:title>\u003Cjats:p>67 sources were included in this scoping review. Five types of avoidable incidents (falls, burns, transport accidents, harm due to self-negligence and due to wandering) emerged, and all but transport accidents were more frequent in cognitively impaired seniors. Differences regarding circumstances were only reported for burns, as scalding was the most prevalent mechanism of injury for this population compared with flames for the general senior population. Multifactorial interventions and implications of other professionals (eg, pharmacist, firefighters) were reported as potential interventions to reduce avoidable incidents. However, few preventive measures were specifically tested in this population.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Conclusions\u003C\u002Fjats:title>\u003Cjats:p>Primary research that screens for cognitive impairment and involves actors (eg, paramedics) to improve our understanding of avoidable incidents leading to ED visits is greatly needed. This knowledge is essential to develop preventive measures tailored to the needs of older cognitively impaired adults.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>",{"EN":2602},"Preventing emergency department (ED) visits and hospitalisations of older adults with cognitive impairment compared with the general senior population: what do we know about avoidable incidents? 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A review of the literature and an analysis of mortality and hospitalisation data to examine patterns of injuries among Canadian seniors. 1997.",{},{"id":23,"text":2873,"url":23,"identifiers":2874},"Public health agency of Canada. If you fall or witness a fall, do you know what to do? 2008. http:\u002F\u002Fwww.phac-aspc.gc.ca\u002Fseniors-aines\u002Fpublications\u002Fpublic\u002Finjury-blessure\u002Ffalls-chutes\u002Findex-fra.php",{},{"id":23,"text":2876,"url":23,"identifiers":2877},"Owens PL , Russo CA , Spector W , et al . Emergency department visits for injurious falls among the elderly, 2006: Statistical Brief #80. 2006. http:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F21452495",{},{"id":23,"text":2879,"url":23,"identifiers":2880},"Kara H , Bayir A , Ak A , et al . Trauma in elderly patients evaluated in a hospital emergency department in Konya, Turkey: a retrospective study. Clin Interv Aging 2013;17.",{"doi":2881},"10.2147\u002FCIA.S56542",{"id":23,"text":2883,"url":23,"identifiers":2884},"Marques de Abrantes KS , Nobre de Menezes T , Andrade Duarte de Farias MdoC , et al . Trauma in elderly people attended by a mobile emergency service. Int Arch Med 2015.doi:10.3823\u002F1679",{"doi":2885},"10.3823\u002F1679",{"id":23,"text":2887,"url":23,"identifiers":2888},"Centers for Disease Control and Prevention. Older adult falls: get the facts. 2015. http:\u002F\u002Fwww.cdc.gov\u002Fhomeandrecreationalsafety\u002Ffalls\u002Fadultfalls.html",{},{"id":23,"text":2890,"url":23,"identifiers":2891},"Public Health Agency of Canada. Report on seniors’ falls in Canada. 2005. http:\u002F\u002Fwww.publications.gc.ca\u002Fpub?id=9.649855&sl=0",{},{"id":23,"text":2893,"url":23,"identifiers":2894},"Lee, 1999, Home accidents in elderly patients presenting to an emergency department, Accid Emerg Nurs, 7, 96, 10.1016\u002FS0965-2302(99)80029-0",{"doi":2895},"10.1016\u002FS0965-2302(99)80029-0",{"id":23,"text":2897,"url":23,"identifiers":2898},"Yeo, 2009, A review of elderly injuries seen in a Singapore emergency department, Singapore Med J, 50, 278",{},{"id":23,"text":2900,"url":23,"identifiers":2901},"10.1016\u002Fj.emc.2006.01.005",{"doi":2900},{"id":23,"text":2903,"url":23,"identifiers":2904},"10.1093\u002Fageing\u002Fafv054",{"doi":2903},{"id":23,"text":2906,"url":23,"identifiers":2907},"10.1186\u002F1471-2318-14-95",{"doi":2906},{"id":23,"text":2909,"url":23,"identifiers":2910},"10.1093\u002Fageing\u002F30.suppl_3.3",{"doi":2909},{"id":23,"text":2912,"url":23,"identifiers":2913},"Ziminski, 2012, Raising the index of suspicion for elder abuse: cognitive impairment, falls, and injury patterns in the emergency department, Geriatr Nurs, 33, 105, 10.1016\u002Fj.gerinurse.2011.12.003",{"doi":2914},"10.1016\u002Fj.gerinurse.2011.12.003",{"id":23,"text":2916,"url":23,"identifiers":2917},"Public Health Agency of Canada. Seniors’ falls in Canada: second report. 2014. http:\u002F\u002Fwww.phac-aspc.gc.ca\u002Fseniors-aines\u002Fpublications\u002Fpublic\u002Finjury-blessure\u002Fseniors_falls-chutes_aines\u002Findex-eng.php",{},{"id":23,"text":2919,"url":23,"identifiers":2920},"Whiteman, 2011, Major trauma in West Virginia dementia patients injury patterns, discharge dispositions and implications for treatment and injury prevention, W V Med J, 107, 48",{},{"id":23,"text":2922,"url":23,"identifiers":2923},"10.1097\u002F00002093-200101000-00003",{"doi":2922},{"id":23,"text":2925,"url":23,"identifiers":2926},"10.1007\u002Fs12603-009-0247-y",{"doi":2925},{"id":23,"text":2928,"url":23,"identifiers":2929},"Ministry of health of B.C. Canada. The evolution of seniors’ falls prevention in British Columbia: working strategically and collectively to reduce the burden and impact of falls and fall-related injury among seniors. 2006. http:\u002F\u002Fwww.health.gov.bc.ca\u002Flibrary\u002Fpublications\u002Fyear\u002F2006\u002Ffalls_report.pdf",{},{"id":23,"text":2931,"url":23,"identifiers":2932},"Kihlgren, 2014, Older patients referred by community nurses to emergency departments: a descriptive cross-sectional follow-up study in a Swedish context, Scand J Caring Sci, 28, 97, 10.1111\u002Fscs.12044",{"doi":2933},"10.1111\u002Fscs.12044",{"id":23,"text":2935,"url":23,"identifiers":2936},"Pfortmueller, 2014, Fall-related emergency department admission: fall environment and settings and related injury patterns in 6357 patients with special emphasis on the elderly, ScientificWorldJournal, 2014, 1, 10.1155\u002F2014\u002F256519",{"doi":2937},"10.1155\u002F2014\u002F256519",{"id":23,"text":2939,"url":23,"identifiers":2940},"Timler, 2015, Head trauma in elderly patients: mechanisms of injuries and CT findings, Adv Clin Exp Med, 24, 1045, 10.17219\u002Facem\u002F27565",{"doi":2941},"10.17219\u002Facem\u002F27565",{"id":23,"text":2943,"url":23,"identifiers":2944},"Ministry of health planning Office of the Provincial Health Officer British Columbia. Prevention of falls and injuries among the elderly : a special report from the Office of the Provincial Health Planning. 2004. http:\u002F\u002Fwww.health.gov.bc.ca\u002Flibrary\u002Fpublications\u002Fyear\u002F2004\u002Ffalls.pdf",{},{"id":23,"text":2946,"url":23,"identifiers":2947},"Department of Health Promotion and Protection. Preventing fall-related injuries among older nova scotians : a strategic framework. 2007.",{},{"id":23,"text":2949,"url":23,"identifiers":2950},"Gyllencreutz, 2015, Outdoor pedestrian fall-related injuries among Swedish senior citizens: injuries and preventive strategies, Scand J Caring Sci, 29, 225, 10.1111\u002Fscs.12153",{"doi":2951},"10.1111\u002Fscs.12153",{"id":23,"text":2953,"url":23,"identifiers":2954},"Wilkins K , Park E . Injuries: heal reports, Stat Canada, 2004:43–8.",{},{"id":23,"text":2956,"url":23,"identifiers":2957},"10.1016\u002Fj.archger.2010.02.014",{"doi":2956},{"id":23,"text":2959,"url":23,"identifiers":2960},"10.1093\u002Fgerona\u002Fglt166",{"doi":2959},{"id":23,"text":2962,"url":23,"identifiers":2963},"10.1016\u002Fj.ajem.2005.12.005",{"doi":2962},{"id":23,"text":2965,"url":23,"identifiers":2966},"Ouellet, 2016, Correlates of cognitive functioning in independent elderly patients discharged home from the emergency department after a minor injury, Int Psychogeriatr, 28, 1313, 10.1017\u002FS104161021600065X",{"doi":2967},"10.1017\u002FS104161021600065X",{"id":23,"text":2969,"url":23,"identifiers":2970},"Welmerink, 2010, Cognition and the risk of hospitalization for serious falls in the elderly: results from the Cardiovascular Health Study, J Gerontol A Biol Sci Med Sci, 65A, 1242, 10.1093\u002Fgerona\u002Fglq115",{"doi":2971},"10.1093\u002Fgerona\u002Fglq115",{"id":23,"text":2973,"url":23,"identifiers":2974},"Taylor, 2017, A home-based, carer-enhanced exercise program improves balance and falls efficacy in community-dwelling older people with dementia, Int Psychogeriatr, 29, 81, 10.1017\u002FS1041610216001629",{"doi":2975},"10.1017\u002FS1041610216001629",{"id":23,"text":2977,"url":23,"identifiers":2978},"National Institute on Aging. Falls and fractures. 2009. https:\u002F\u002Fwww.nia.nih.gov\u002Fhealth\u002Fpublication\u002Ffalls-and-fractures",{},{"id":23,"text":2980,"url":23,"identifiers":2981},"Beaudoin, 2016, Prevalence and detection of prescription opioid misuse and prescription opioid use disorder among emergency department patients 50 years of age and older: performance of the prescription drug use questionnaire, patient version, The American Journal of Geriatric Psychiatry, 24, 627, 10.1016\u002Fj.jagp.2016.03.010",{"doi":2982},"10.1016\u002Fj.jagp.2016.03.010",{"id":23,"text":2984,"url":23,"identifiers":2985},"10.1111\u002Fj.1532-5415.2007.01144.x",{"doi":2984},{"id":23,"text":2987,"url":23,"identifiers":2988},"National Institute on Aging. Driving and dementia: health professionals can play important role. 2002. https:\u002F\u002Fwww.nia.nih.gov\u002Falzheimers\u002Ffeatures\u002Fdriving-and-dementia-health-professionals-can-play-important-role",{},{"id":23,"text":2990,"url":23,"identifiers":2991},"Alden, 2005, Burn injury in patients with dementia: an impetus for prevention, J Burn Care Rehabil, 26, 267",{},{"id":23,"text":2993,"url":23,"identifiers":2994},"Ehrlich, 2005, Elderly patients discharged home from the emergency department with minor burns, Burns, 31, 717, 10.1016\u002Fj.burns.2004.12.008",{"doi":2995},"10.1016\u002Fj.burns.2004.12.008",{"id":23,"text":2997,"url":23,"identifiers":2998},"10.1186\u002F1472-6963-10-327",{"doi":2997},{"id":23,"text":3000,"url":23,"identifiers":3001},"Lester, 2008, Smoking in the nursing home: a case report and literature review, J Am Med Dir Assoc, 9, 201, 10.1016\u002Fj.jamda.2007.09.002",{"doi":3002},"10.1016\u002Fj.jamda.2007.09.002",{"id":23,"text":3004,"url":23,"identifiers":3005},"10.1093\u002Fageing\u002F25.3.214",{"doi":3004},{"id":23,"text":3007,"url":23,"identifiers":3008},"10.1097\u002F01.JGP.0000230661.32735.c0",{"doi":3007},{"id":23,"text":3010,"url":23,"identifiers":3011},"Charles, 2015, Self-report measures of well-being predict incident harm due to self-neglect in cognitively impaired seniors who live alone, J Alzheimers Dis, 44, 425, 10.3233\u002FJAD-141671",{"doi":3012},"10.3233\u002FJAD-141671",{"id":23,"text":3014,"url":23,"identifiers":3015},"10.1046\u002Fj.0306-5251.2001.01401.x",{"doi":3014},{"id":23,"text":3017,"url":23,"identifiers":3018},"Canadian Institute for Health Information. Hospitalizations and emergency department visits due to opioid poisoning in Canada. 2016. https:\u002F\u002Fsecure.cihi.ca\u002Ffree_products\u002FOpioid Poisoning Report EN.pdf",{},{"id":23,"text":3020,"url":23,"identifiers":3021},"Tierney, 2001, Identification of those at greatest risk of harm among cognitively impaired people who live alone, Aging, Neuropsychology, and Cognition, 8, 182, 10.1076\u002Fanec.8.3.182.829",{"doi":3022},"10.1076\u002Fanec.8.3.182.829",{"id":23,"text":3024,"url":23,"identifiers":3025},"10.4065\u002F79.11.1417",{"doi":3024},{"id":23,"text":3027,"url":23,"identifiers":3028},"10.1046\u002Fj.1532-5415.2002.50314.x",{"doi":3027},{"id":23,"text":3030,"url":23,"identifiers":3031},"10.1177\u002F0891988708316861",{"doi":3030},{"id":23,"text":3033,"url":23,"identifiers":3034},"Dalsania, 2006, Dementia dashboard: a proactive risk reduction management guideline, Top Geriatr Rehabil, 22, 228, 10.1097\u002F00013614-200607000-00005",{"doi":3035},"10.1097\u002F00013614-200607000-00005",{"id":23,"text":3037,"url":23,"identifiers":3038},"10.1002\u002Fgps.2095",{"doi":3037},{"id":23,"text":3040,"url":23,"identifiers":3041},"10.1017\u002FS1355617700644065",{"doi":3040},{"id":23,"text":3043,"url":23,"identifiers":3044},"Booth, 2015, Falls prevention interventions in older adults with cognitive impairment: a systematic review of reviews, Int J Ther Rehabil, 22, 289, 10.12968\u002Fijtr.2015.22.6.289",{"doi":3045},"10.12968\u002Fijtr.2015.22.6.289",{"id":23,"text":3047,"url":23,"identifiers":3048},"10.1197\u002Fj.aem.2005.01.017",{"doi":3047},{"id":23,"text":3050,"url":23,"identifiers":3051},"10.1016\u002Fj.annemergmed.2010.06.560",{"doi":3050},{"id":23,"text":3053,"url":23,"identifiers":3054},"Lee, 2016, Paramedics assessing Elders at Risk for Independence Loss (PERIL): derivation, reliability and comparative effectiveness of a clinical prediction rule, CJEM, 18, 121, 10.1017\u002Fcem.2016.14",{"doi":3055},"10.1017\u002Fcem.2016.14",{"id":23,"text":3057,"url":23,"identifiers":3058},"10.2217\u002Fahe.12.68",{"doi":3057},{"id":23,"text":3060,"url":23,"identifiers":3061},"Al-Aama, 2011, Falls in the elderly : spectrum and prevention, Can Fam physician, 57, 771",{},{"id":23,"text":3063,"url":23,"identifiers":3064},"Institut national de santé publique du Québec. Prévenir les chutes chez les aînés vivant à domicile: Volet soutien à domicile-Intervention multifactorielle personnalisée [IMP]. 2017.",{},{"id":23,"text":3066,"url":23,"identifiers":3067},"Fuller, 2000, Falls in the elderly, Am Fam Physician, 61, 2159",{},{"id":23,"text":3069,"url":23,"identifiers":3070},"10.1111\u002Fj.1532-5415.2008.01739.x",{"doi":3069},{"id":23,"text":3072,"url":23,"identifiers":3073},"Canadian Institute for Health Information. Sources of potentially avoidable emergency department visits. 2014. https:\u002F\u002Fsecure.cihi.ca\u002Ffree_products\u002FED_Report_ForWeb_EN_Final.pdf",{},{"id":23,"text":3075,"url":23,"identifiers":3076},"Alldred DP , Raynor DK , Hughes C , et al . Interventions to optimise prescribing for older people in care homes. Alldred DP , ed. Cochrane database of systematic reviews. Chichester, UK: John Wiley & Sons, Ltd, 2013.",{"doi":3077},"10.1002\u002F14651858.CD009095.pub2",{"id":23,"text":3079,"url":23,"identifiers":3080},"10.1111\u002Facem.12488",{"doi":3079},{"id":23,"text":3082,"url":23,"identifiers":3083},"Canada PHA of Public Health Agency of Canada. The national blueprint for injury prevention in older drivers. 2009.",{},{"id":3085,"createTime":3086,"updateTime":3087,"relativeEntities":3088,"slug":3089,"properties":3090,"entityType":137,"verifyStatus":138,"verifyTime":3099,"verifyNote":139,"languages":3100,"translateLanguages":23,"viewCount":24,"primaryUrl":3101,"fullTextUrl":3102,"authors":3103,"publicationType":439,"publisherRelationship":3260,"citationCount":24,"citationInfo":3305,"publishDate":3307,"publishYear":2784,"citationAnalyzeStatus":22,"lastCitationAnalyze":3308,"indexDatabases":3309,"openAccess":23,"references":3310,"isForceReanalyzing":582},"8eb0e1e4-a32e-40e1-96e5-2d24136e9419","2025-01-26T04:05:27.462+00:00","2025-08-04T04:35:20.397+00:00",[],"Enhancing-prescribing-of-guideline-recommended-medications-for-ischaemic-heart-diseases-a-systematic-review-and-meta-analysis-of-interventions-targeted-at-healthcare-professionals",{"abstract":3091,"title":3093,"gsPaper":3095,"doi":3097},{"EN":3092},"Objectives Ischaemic heart diseases (IHDs) are a leading cause of death worldwide. Although prescribing according to guidelines improves health outcomes, it remains suboptimal. We determined whether interventions targeted at healthcare professionals are effective to enhance prescribing and health outcomes in patients with IHDs.\n\nMethods We systematically searched PubMed and EMBASE for studies published between 1 January 2000 and 31 August 2017. We included original studies of interventions targeted at healthcare professionals to enhance prescribing guideline-recommended medications for IHDs. We only included randomised controlled trials (RCTs). Main outcomes were the proportion of eligible patients receiving guideline-recommended medications, the proportion of patients achieving target blood pressure and target low-density lipoprotein-cholesterol (LDL-C)\u002Fcholesterol level and mortality rate. Meta-analyses were performed using the inverse-variance method and the random effects model. The quality of evidence was assessed using the Grading of Recommendations, Assessment, Development, and Evaluation approach.\n\nResults We included 13 studies, 4 RCTs (1869 patients) and 9 cluster RCTs (15 224 patients). 11 out of 13 studies were performed in North America and Europe. Interventions were of organisational or professional nature. The interventions significantly enhanced prescribing of statins\u002Flipid-lowering agents (OR 1.23; 95% CI 1.07 to 1.42, P=0.004), but not other medications (aspirin\u002Fantiplatelet agents, beta-blockers, ACE inhibitors\u002Fangiotensin II receptor blockers and the composite of medications). There was no significant association between the interventions and improved health outcomes (target LDL-C and mortality) except for target blood pressure (OR 1.46; 95% CI 1.11 to 1.93; P=0.008). The evidence was of moderate or high quality for all outcomes.\n\nConclusions Organisational and professional interventions improved prescribing of statins\u002Flipid-lowering agents and target blood pressure in patients with IHDs but there was little evidence of change in other outcomes.\n\nPROSPERO registration number [CRD42016039188][1].\n\n [1]: http:\u002F\u002FCRD42016039188",{"EN":3094},"Enhancing prescribing of guideline-recommended medications for ischaemic heart diseases: a systematic review and meta-analysis of interventions targeted at healthcare 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BMC Public Health 2014;14:833–33. 10.1186\u002F1471-2458-14-833\nDiviani N, van den Putte B, Giani S, et al. . Low health literacy and evaluation of online health information: a systematic review of the literature. J Med Internet Res 2015;17:e112. 10.2196\u002Fjmir.4018\nNorman CD, Skinner HA. eHealth literacy: essential skills for consumer health in a networked world. J Med Internet Res 2006;8:e9. 10.2196\u002Fjmir.8.2.e9\nMitsutake S, Shibata A, Ishii K, et al. . Associations of eHealth literacy with health behavior among adult Internet users. J Med Internet Res 2016;18:e192. 10.2196\u002Fjmir.5413\nDuong TV, Chiu C-H, Lin C-Y, et al. . E-healthy diet literacy scale and its relationship with behaviors and health outcomes in Taiwan. Health Promot Int 2020. 10.1093\u002Fheapro\u002Fdaaa033. [Epub ahead of print: 08 Apr 2020].\nOwen L, Corfe B. The role of diet and nutrition on mental health and wellbeing. Proc Nutr Soc 2017;76:425–6. 10.1017\u002FS0029665117001057\nMarx W, Moseley G, Berk M, et al. . Nutritional psychiatry: the present state of the evidence. Proc Nutr Soc 2017;76:427–36. 10.1017\u002FS0029665117002026\nMolendijk M, Molero P, Ortuño Sánchez-Pedreño F, et al. . Diet quality and depression risk: a systematic review and dose-response meta-analysis of prospective studies. J Affect Disord 2018;226:346–54. 10.1016\u002Fj.jad.2017.09.022\nLi Y, Lv M-R, Wei Y-J, et al. . Dietary patterns and depression risk: a meta-analysis. Psychiatry Res 2017;253:373–82. 10.1016\u002Fj.psychres.2017.04.020\nGasmi A, Noor S, Tippairote T, et al. . Individual risk management strategy and potential therapeutic options for the COVID-19 pandemic. Clin Immunol 2020;215:108409. 10.1016\u002Fj.clim.2020.108409\nZhang L, Liu Y. Potential interventions for novel coronavirus in China: a systematic review. J Med Virol 2020;92:479–90. 10.1002\u002Fjmv.25707\nKakodkar P, Kaka N, Baig MN. A comprehensive literature review on the clinical presentation, and management of the pandemic coronavirus disease 2019 (COVID-19). Cureus 2020;12:e7560. 10.7759\u002Fcureus.7560\nKritas SK, Ronconi G, Caraffa A, et al. . Mast cells contribute to coronavirus-induced inflammation: new anti-inflammatory strategy. J Biol Regul Homeost Agents. In Press 2020;34:34. 10.23812\u002F20-Editorial-Kritas\nHuong NT, Ha LTH, Tien TQ. Determinants of health-related quality of life among elderly: evidence from chi Linh town, Vietnam. Asia Pac J Public Health 2017;29:84S–93. 10.1177\u002F1010539517704041\nHoi LV, Chuc NT, Lindholm L. Health-related quality of life, and its determinants, among older people in rural Vietnam. BMC Public Health 2010;10:549–49. 10.1186\u002F1471-2458-10-549\nThe Lancet The gendered dimensions of COVID-19. Lancet 2020;395:1168 10.1016\u002FS0140-6736(20)30823-0\nNguyen LH, Tran BX, Hoang Le QN, et al. . Quality of life profile of general Vietnamese population using EQ-5D-5L. Health Qual Life Outcomes 2017;15:199–99. 10.1186\u002Fs12955-017-0771-0\nTan A, Lowe S, Henry A. Nausea and vomiting of pregnancy: effects on quality of life and day-to-day function. Aust N Z J Obstet Gynaecol 2018;58:278–90. 10.1111\u002Fajo.12714\nGałązka I, Drosdzol-Cop A, Naworska B, et al. . Changes in the sexual function during pregnancy. J Sex Med 2015;12:445–54. 10.1111\u002Fjsm.12747\nChang S-R, Ho H-N, Chen K-H, et al. . Depressive symptoms as a predictor of sexual function during pregnancy. 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analyse injuries related to manual and electric scooter use from January 2016 up to and including July 2019.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Setting\u003C\u002Fjats:title>\u003Cjats:p>Electric scooter rental services were launched in Denmark in January 2019. The services were provided by private companies. Although rules for handling and riding scooters have been established, no reports either before or after introduction of electric scooters anticipated the full extent of use, and injuries to riders and pedestrians.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Participants\u003C\u002Fjats:title>\u003Cjats:p>All patient records mentioning manual or electric scooters. Records were reviewed, and data were stratified according to two groups: manual and electric scooters.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Interventions\u003C\u002Fjats:title>\u003Cjats:p>A predefined survey was completed in all cases where ‘scooter’ was present. This contained variables such as type of scooter, type of participant, mechanism of injury, acuity, intoxication, referral to treatment facility.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Outcome measures\u003C\u002Fjats:title>\u003Cjats:p>Among incidents involving scooters, summary statistics on continuous and categorical variables of interest were reported.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Results\u003C\u002Fjats:title>\u003Cjats:p>468 scooter-related injuries were recorded. We found that manual scooter riders were more likely to be children under the age of 15; fall alone—involving no other party; sustain contusions, sprains and lacerations; and bruise either their fingers or toes. Riders of electric scooters were likely to be 18–25 years, sustain facial bruising and lacerations requiring sutures, and be under the influence of alcohol or drugs. Non-riders of electric scooters were mostly elderly people who tripped over scooters, consequently sustaining moderate to severe injuries.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Conclusion\u003C\u002Fjats:title>\u003Cjats:p>There were two different types of population sustaining injuries from manual and electric scooters, respectively. The proportion of non-riders injured by electric scooters were surprisingly large (17%), and while electric scooters are here to stay, several apparently preventable injuries occur as a result of reckless driving and discarded electric scooters. Current rules for usage might not prevent unnecessary accidents and secure traffic safety and the lives of older individuals.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>",{"EN":4072},"Injury from electric scooters in Copenhagen: a retrospective cohort study",{"VOID":4074},"31871261",{"VOID":4076},"10.1136\u002Fbmjopen-2019-033988",[141],"https:\u002F\u002Fbmjopen.bmj.com\u002Flookup\u002Fdoi\u002F10.1136\u002Fbmjopen-2019-033988",[4080,4099,4116,4133],{"id":4081,"sortIndex":24,"researcher":23,"roles":4082,"affiliations":4083,"properties":4092},"d0bd2d02-763f-4238-9aaa-ee71f2a54e09",[],[4084],{"id":4085,"sortIndex":24,"affiliation":4086,"properties":23},"08ae4d96-283a-4ec5-a3d3-c05aa817c216",{"id":4085,"createTime":23,"updateTime":23,"relativeEntities":4087,"slug":23,"properties":4088,"entityType":23,"verifyStatus":23,"verifyTime":23,"verifyNote":23,"languages":23,"translateLanguages":23,"viewCount":23,"url":23,"parentIds":4091,"statistic":23},[],{"title":4089},{"EN":4090},"Emergency 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and student teachers in Germany are a high-risk population for stress and stress-related mental health problems. This often leads to early retirement in subsequent professional life. Various trials have demonstrated positive effects of stress prevention training on the perceived stress and stress-related symptoms of teachers. Although many studies show positive effects of mindfulness-based stress interventions, there is not yet any mindfulness-based intervention for teachers or student teachers in Germany. The aim of this trial is to evaluate a training that combines mindfulness-based and cognitive interventions into one programme, addressing to the specific burdens of student teachers.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Methods and analysis\u003C\u002Fjats:title>\u003Cjats:p>This study protocol presents a prospective block-randomised controlled trial. Assessment will take place at three time points (baseline, post-intervention, 3-month follow-up) for an intervention and waiting control group, and at a fourth assessment point for the waiting control group after receiving the training. The aim is to evaluate the effects of mindfulness-based stress prevention on stress, psychological morbidity, burnout and self-efficacy using validated measures. Participants are student teachers from German teacher training colleges and participation will be voluntary. The targeted total sample size is 96 at 3-month follow-up. The training will comprise three 4-hour sessions conducted every 2 weeks. The control group will participate in the training after the 3-month follow-up. The allotment will be randomised with a stratified allocation ratio by gender. After descriptive statistics have been evaluated, inferential statistical analysis will be conducted using repeated measures analysis of variance with interactions between time and group. 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Was Lehrerinnen und Lehrer gesund hält: Empirische Ergebnisse zur Bedeutung psychosozialer Ressourcen im Lehrerberuf. Göttingen: Vandenhoeck & Ruprecht, 2013.",{},{"id":23,"text":4402,"url":23,"identifiers":4403},"Döring-Seipel E , Dauber H . What keeps teachers healthy - The importance of resources, subjective evaluation and handling of the burden on the health of teachers. School Education Today 2010;2.",{},{"id":23,"text":4405,"url":23,"identifiers":4406},"Under Brink T , Bauer J . Teacher health prevention: coaching groups for school teachers according to the Freiburg model. Supervision (42006): System School. Weinheim: Beltz, 2006.",{},{"id":23,"text":4408,"url":23,"identifiers":4409},"Schaarschmidt U , Kieschke U . Potsdam training model with trainees. Teachers and student teachers. In: Schaarschmidt U , Kieschke U , eds. Prepared for everyday school life - psychological support for teachers. Weinheim \u002F Basel: Beltz, 2007.",{},{"id":23,"text":4411,"url":23,"identifiers":4412},"Pixner S . Evaluation of a health prevention measure for Baden-Wuerttemberg teachers (teacher health project) according to the \"Teacher Coaching according to the Freiburg Model\" in two presentation modes [Inaugural dissertation]: University of Potsdam, 2014.",{},{"id":23,"text":4414,"url":23,"identifiers":4415},"Jansen LJ . Stress-Resistenz-Training (SRT): Konzeption und Evaluation des Gruppentraingsprogramms zur Verbesserung der Stressresistenz. Berlin: Logos, 2005.",{},{"id":23,"text":4417,"url":23,"identifiers":4418},"Hillert, 2014, Mental illness of teachers: occupational therapy and prevention services, Empirical Education, 28, 190",{},{"id":23,"text":4420,"url":23,"identifiers":4421},"Büttner, 2014, Mindfulness and health in the teaching profession: relationships between trait mindfulness and stress-related variables, Empirical Education, 28, 171",{},{"id":23,"text":4423,"url":23,"identifiers":4424},"Kabat-Zinn J . Find peace in everyday life. Frankfurt am Main: Fischer Verlag, 2009.",{},{"id":23,"text":4426,"url":23,"identifiers":4427},"Kabat-Zinn J . Stress management through the practice of mindfulness. Arbor Publisher: Freiburg, 1999.",{},{"id":23,"text":4429,"url":23,"identifiers":4430},"10.1016\u002Fj.jpsychores.2015.03.009",{"doi":4429},{"id":23,"text":4432,"url":23,"identifiers":4433},"10.1007\u002Fs10865-007-9130-7",{"doi":4432},{"id":23,"text":4435,"url":23,"identifiers":4436},"Dundas, 2016, Mindfulness based stress reduction for academic evaluation anxiety: a naturalistic longitudinal study, J College Stud Psychother, 30, 114, 10.1080\u002F87568225.2016.1140988",{"doi":4437},"10.1080\u002F87568225.2016.1140988",{"id":23,"text":4439,"url":23,"identifiers":4440},"Sampl, 2017, A randomized controlled pilot intervention study of a Mindfulness-Based Self-Leadership Training (MBSLT) on stress and performance, Mindfulness, 8, 1393, 10.1007\u002Fs12671-017-0715-0",{"doi":4441},"10.1007\u002Fs12671-017-0715-0",{"id":23,"text":4443,"url":23,"identifiers":4444},"10.1037\u002F1931-3918.1.2.105",{"doi":4443},{"id":23,"text":4446,"url":23,"identifiers":4447},"Poulin, 2008, Mindfulness training as an evidenced-based approach to reducing stress and promoting well-being among human services professionals, Int J Health Promot Educ, 46, 72, 10.1080\u002F14635240.2008.10708132",{"doi":4448},"10.1080\u002F14635240.2008.10708132",{"id":23,"text":4450,"url":23,"identifiers":4451},"10.1037\u002Fspq0000035",{"doi":4450},{"id":23,"text":4453,"url":23,"identifiers":4454},"Jennings, 2011, Improving classroom learning environments by cultivating awareness and resilience in education (CARE): Results of two pilot studies, Journal of Classroom Interaction, 46, 37",{},{"id":23,"text":4456,"url":23,"identifiers":4457},"Kaerner, 2017, Effekte achtsamkeitsbasierter Interventionen zur Verbesserung der Stressbewältigung von Lehrpersonen: eine Zusammenfassung aktueller Forschungsbefunde, Wirtschaft & & Erziehung, 69, 11",{},{"id":23,"text":4459,"url":23,"identifiers":4460},"Cook, 2017, Promoting secondary teachers’ well-being and intentions to implement evidence-based practices: randomized evaluation of the achiever resilience curriculum, Psychol Sch, 54, 13, 10.1002\u002Fpits.21980",{"doi":4461},"10.1002\u002Fpits.21980",{"id":23,"text":4463,"url":23,"identifiers":4464},"10.1353\u002Fpbm.2005.0092",{"doi":4463},{"id":23,"text":4466,"url":23,"identifiers":4467},"10.1097\u002F01.psy.0000151491.80178.78",{"doi":4466},{"id":23,"text":4469,"url":23,"identifiers":4470},"Fliege, 2001, Validierung des “Perceived Stress Questionnaire“ (PSQ) an einer deutschen Stichprobe, Diagnostica, 47, 142, 10.1026\u002F\u002F0012-1924.47.3.142",{"doi":4471},"10.1026\u002F\u002F0012-1924.47.3.142",{"id":23,"text":4473,"url":23,"identifiers":4474},"Levenstein, 1993, Development of the perceived stress questionnaire: a new tool for psychosomatic research, J Psychosom Res, 37, 19, 10.1016\u002F0022-3999(93)90120-5",{"doi":4475},"10.1016\u002F0022-3999(93)90120-5",{"id":23,"text":4477,"url":23,"identifiers":4478},"Derogatis LR , Fitzpatrick M . The SCL-90-R, the Brief Symptom Inventory (BSI), and the BSI-18. Maruish ME , ed. The use of psychological testing for treatment planning and outcomes assessment: Instruments for adults. Mahwah, NJ: Lawrence Erlbaum Associates, 2004:1–41.",{},{"id":23,"text":4480,"url":23,"identifiers":4481},"Derogatis LR . BSI brief symptom inventory: administration, scoring, and procedure manual. 4th ed. Minneapolis: MN: National Computer Systems, 1993.",{},{"id":23,"text":4483,"url":23,"identifiers":4484},"Franke GH . Brief Symptom Inventory von LR Derogatis (Kurzform der SCL- 90 - R). Deutsche Version. Manual. 1st ed. Göttingen: Beltz Test GmbH, 2000.",{},{"id":23,"text":4486,"url":23,"identifiers":4487},"Buessing, 1992, Untersuchung einer deutschen Fassung des Maslach Burnout Inventory (MBI-D), Diagnostica, 38, 328",{},{"id":23,"text":4489,"url":23,"identifiers":4490},"Beierlein, 2013, Kurzskala zur Erfassung allgemeiner Selbstwirksamkeitserwartungen (ASKU), methoden, daten, analysen, 7, 251",{},{"id":23,"text":4492,"url":23,"identifiers":4493},"Beierlein C , Kovaleva A , Kemper CJ , et al . Ein Messinstrument zur Erfassung subjektiver Kompetenzerwartungen: Allgemeine Selbstwirksamkeit Kurzskala (ASKU). Mannheim: GESIS - Leibniz-Institut für Sozialwissenschaften, 2012.",{},{"id":23,"text":4495,"url":23,"identifiers":4496},"10.1186\u002Fs13063-014-0533-9",{"doi":4495},{"id":23,"text":4498,"url":23,"identifiers":4499},"Kuhlmann, 2016, Coping with stress in medical students: results of a randomized controlled trial using a mindfulness-based stress prevention training (MediMind) in Germany, BMC Med Educ, 16, 316, 10.1186\u002Fs12909-016-0833-8",{"doi":4500},"10.1186\u002Fs12909-016-0833-8",{"id":23,"text":4502,"url":23,"identifiers":4503},"Kornfield J . Bringing home the dharma: awakening right where you are. Boston: Shambala, 2012.",{},{"id":23,"text":4505,"url":23,"identifiers":4506},"10.1037\u002Fa0038898",{"doi":4505},{"id":23,"text":4508,"url":23,"identifiers":4509},"Thichn NH . Das Wunder der Achtsamkeit. 1st edn. Berlin: Theseus, 2006.",{},{"id":23,"text":4511,"url":23,"identifiers":4512},"Hayes SC , Strosahl KD , Wilson KG . Acceptance and commitement therapy: an experimental approach to behavior change. New York: Guilford Press, 1999.",{},{"id":23,"text":4514,"url":23,"identifiers":4515},"Acceptance, 2016, Relational frame theory, and the third wave of behavioral and cognitive therapies–republished article, Behavior therapy, 47, 869, 10.1016\u002Fj.beth.2016.11.006",{"doi":4516},"10.1016\u002Fj.beth.2016.11.006",{"id":23,"text":4518,"url":23,"identifiers":4519},"Kaltwasser V , Präsenz P . Persönlichkeit und Präsenz. Achtsamkeit im Lehrerberuf. 1st edn. Weinheim & Basel: Beltz, 2010.",{},{"id":23,"text":4521,"url":23,"identifiers":4522},"Bennett-Levy J , Butler G , Fennell M , et al , eds. Oxford Guide to Behavioural Experiments in Cognitive Therapy. 1st ed. New York: Oxford University Press, 2004.",{"doi":4523},"10.1093\u002Fmed:psych\u002F9780198529163.003.0001",{"id":23,"text":4525,"url":23,"identifiers":4526},"Rahl, 2017, Brief mindfulness meditation training reduces mind wandering: The critical role of acceptance, Emotion, 17, 224, 10.1037\u002Femo0000250",{"doi":4527},"10.1037\u002Femo0000250",{"id":23,"text":4529,"url":23,"identifiers":4530},"Wengenroth M . Therapie-Tools Akzeptanz und Commitementtherapie. 2nd edn. Weinheim Basel: Beltz, 2017.",{},{"id":23,"text":4532,"url":23,"identifiers":4533},"Kaluza G . Stressbewätligung. Training manual on psychological health promotion. Berlin Heidelberg: Springer-Verlag, 2011.",{},{"id":23,"text":4535,"url":23,"identifiers":4536},"Beck AT , Rush AJ , Shaw BF , et al . Cognitive therapy of depression. New York: The Guilford Press, 1979.",{},{"id":23,"text":4538,"url":23,"identifiers":4539},"Ellis A . Humanistic psychotherapy. The rational-emotive approach. New York: Mcgraw-Hill, 1973.",{},{"id":23,"text":4541,"url":23,"identifiers":4542},"Stavemann HH . Socratic discussion in therapy and counseling: A guide for psychotherapists, counselors and pastoral counselors. 1st edn. Weinheim Basel Berlin: Beltz, 2002.",{},{"id":23,"text":4544,"url":23,"identifiers":4545},"Wilken B . Methods of cognitive restructuring. A Guide to Psychotherapeutic Practice. 7th edn. Stuttgart: Kohlhammer, 2015.",{},{"id":23,"text":4547,"url":23,"identifiers":4548},"Seiwert L . Das 1 x 1 des Zeitmanagement. 36th ed. Munich: Graefe and Unzer, 2014.",{},{"id":23,"text":4550,"url":23,"identifiers":4551},"Maslach C , Jackson SE , Leiter MP . Maslach burnout inventory manual. Palo Alto, CA: Consulting Psychologists Press, 1996.",{},{"id":23,"text":4553,"url":23,"identifiers":4554},"10.1002\u002Fjob.4030020205",{"doi":4553},{"id":23,"text":4556,"url":23,"identifiers":4557},"McDonald RP . Test theory: a unified treatment. Mahwah: Erlbaum, 1999.",{},{"id":23,"text":4559,"url":23,"identifiers":4560},"10.5271\u002Fsjweh.3449",{"doi":4559},{"id":23,"text":4562,"url":23,"identifiers":4563},"Bortz J . Statistics: for social scientists. 4th ed. Berlin: Springer-Verlag, 2013.",{},{"id":23,"text":4565,"url":23,"identifiers":4566},"Tabachnick B , Fidell L . Using multivariate statistics. Harlow: Pearson Education Limited, 2014.",{},{"id":23,"text":4568,"url":23,"identifiers":4569},"Cohen J . The effect size. Statistical power analysis for the behavioral sciences, 1988:77–83.",{},{"id":4571,"createTime":4572,"updateTime":4572,"relativeEntities":4573,"slug":4574,"properties":4575,"entityType":137,"verifyStatus":138,"verifyTime":4590,"verifyNote":139,"languages":4591,"translateLanguages":23,"viewCount":24,"primaryUrl":4592,"fullTextUrl":23,"authors":4593,"publicationType":439,"publisherRelationship":4924,"citationCount":4968,"citationInfo":4969,"publishDate":4971,"publishYear":2784,"citationAnalyzeStatus":22,"lastCitationAnalyze":23,"indexDatabases":4972,"openAccess":23,"references":4973,"isForceReanalyzing":582},"9c7d9c68-f123-4c66-96e1-a4643fe60b58","2025-02-04T20:35:19.528+00:00",[],"Does-perturbation-based-balance-training-prevent-falls-among-individuals-with-chronic-stroke-A-randomised-controlled-trial",{"mag":4576,"pmc":4578,"openalex":4580,"abstract":4582,"title":4584,"pm":4586,"doi":4588},{"VOID":4577},"2887272762",{"VOID":4579},"6104758",{"VOID":4581},"W2887272762",{"EN":4583},"\u003Cjats:sec>\u003Cjats:title>Objectives\u003C\u002Fjats:title>\u003Cjats:p>No intervention has been shown to prevent falls poststroke. We aimed to determine if perturbation-based balance training (PBT) can reduce falls in daily life among individuals with chronic stroke.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Design\u003C\u002Fjats:title>\u003Cjats:p>Assessor-blinded randomised controlled trial.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Setting\u003C\u002Fjats:title>\u003Cjats:p>Two academic hospitals in an urban area.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Interventions\u003C\u002Fjats:title>\u003Cjats:p>Participants were allocated using stratified blocked randomisation to either ‘traditional’ balance training (control) or PBT. PBT focused on improving responses to instability, whereas traditional balance training focused on maintaining stability during functional tasks. Training sessions were 1 hour twice\u002Fweek for 6 weeks. Participants were also invited to complete 2 ‘booster’ training sessions during the follow-up.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Participants\u003C\u002Fjats:title>\u003Cjats:p>Eighty-eight participants with chronic stroke (>6 months poststroke) were recruited and randomly allocated one of the two interventions. Five participants withdrew; 42 (control) and 41 (PBT group) were included in the analysis.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Primary and secondary outcome measures\u003C\u002Fjats:title>\u003Cjats:p>The primary outcome was rate of falls in the 12 months post-training. Negative binomial regression was used to compare fall rates between groups. Secondary outcomes were measures of balance, mobility, balance confidence, physical activity and social integration.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Results\u003C\u002Fjats:title>\u003Cjats:p>PBT participants reported 53 falls (1.45 falls\u002Fperson-year) and control participants reported 64 falls (1.72 falls\u002Fperson-year; rate ratio: 0.85(0.42 to 1.69); p=0.63). Per-protocol analysis included 32 PBT and 34 control participants who completed at least 10\u002F12 initial training sessions and 1 booster session. Within this subset, PBT participants reported 32 falls (1.07 falls\u002Fperson-year) and control participants reported 57 falls (1.75 falls\u002Fperson-year; rate ratio: 0.62(0.29 to 1.30); p=0.20). PBT participants had greater improvement in reactive balance control than the control group, and these improvements were sustained 12 months post-training. There were no intervention-related serious adverse effects.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Conclusions\u003C\u002Fjats:title>\u003Cjats:p>The results are inconclusive. PBT may help to prevent falls in daily life poststroke, but ongoing training may be required to maintain the benefits.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Trial registration number\u003C\u002Fjats:title>\u003Cjats:p>\u003Cjats:ext-link xmlns:xlink=\"http:\u002F\u002Fwww.w3.org\u002F1999\u002Fxlink\" xlink:href=\"ISRCTN05434601\" ext-link-type=\"isrctn\" specific-use=\"clinicaltrial results\">ISRCTN05434601\u003C\u002Fjats:ext-link>; Results.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>",{"EN":4585},"Does perturbation-based balance training prevent falls among individuals with chronic stroke? 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