[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"_public_publisher_byId_50975638-ba35-4024-afa3-ae7e9fdebdb2":3,"_public_publication_all{\"sortAscending\":false,\"sortField\":\"updateTime\",\"page\":0,\"size\":10,\"facet\":true,\"searchKey\":\"publisherId:50975638-ba35-4024-afa3-ae7e9fdebdb2,\"}":25},{"code":4,"data":5,"meta":20},"SUCCESS",{"id":6,"createTime":7,"updateTime":8,"relativeEntities":9,"slug":10,"properties":11,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":22,"manageAffiliations":23,"indexDatabases":24,"url":20,"thumbnailPath":20,"statistic":20,"gsStatistic":20,"type":20,"analyzePriority":20},"50975638-ba35-4024-afa3-ae7e9fdebdb2","2024-08-30T21:46:08.626+00:00","2025-02-08T17:28:25.991+00:00",[],"Annual-Reviews",{"issn":12,"eissn":14,"title":16},{"VOID":13},"1056-8700",{"VOID":15},"1545-4266",{"EN":17},"Annual Reviews","PUBLISHER","PENDING",null,0,[],[],[],{"meta":26,"data":28},{"total":27},"35",[29,361,447,989,1557,1982,2405,2852,3537,3623],{"id":30,"createTime":31,"updateTime":31,"relativeEntities":32,"slug":33,"properties":34,"entityType":48,"verifyStatus":49,"verifyTime":31,"verifyNote":50,"syncStatus":19,"languages":51,"translateLanguages":20,"viewCount":21,"primaryUrl":53,"fullTextUrl":20,"authors":54,"publicationType":95,"publisherRelationship":96,"citationCount":113,"citationInfo":114,"publishDate":125,"publishYear":126,"citationAnalyzeStatus":19,"lastCitationAnalyze":20,"indexDatabases":20,"openAccess":20,"references":127,"isForceReanalyzing":360},"e1afb672-3bd4-4c0d-abec-748477d2c746","2024-09-18T23:57:16.996+00:00",[],"Chaperonin-Mediated-Protein-Folding",{"mag":35,"keywords":37,"openalex":38,"abstract":40,"title":42,"pm":44,"doi":46},{"VOID":36},"2130661537",{},{"VOID":39},"W2130661537",{"EN":41},"\u003Cjats:p> ▪ Abstract  Molecular chaperones are required to assist folding of a subset of proteins in Escherichia coli. We describe a conceptual framework for understanding how the GroEL-GroES system assists misfolded proteins to reach their native states. The architecture of GroEL consists of double toroids stacked back-to-back. However, most of the fundamentals of the GroEL action can be described in terms of the single ring. A key idea in our framework is that, with coordinated ATP hydrolysis and GroES binding, GroEL participates actively by repeatedly unfolding the substrate protein (SP), provided that it is trapped in one of the misfolded states. We conjecture that the unfolding of SP becomes possible because a stretching force is transmitted to the SP when the GroEL particle undergoes allosteric transitions. Force-induced unfolding of the SP puts it on a higher free-energy point in the multidimensional energy landscape from which the SP can either reach the native conformation with some probability or be trapped in one of the competing basins of attraction (i.e., the SP undergoes kinetic partitioning). The model shows, in a natural way, that the time scales in the dynamics of the allosteric transitions are intimately coupled to folding rates of the SP. Several scenarios for chaperonin-assisted folding emerge depending on the interplay of the time scales governing the cycle. Further refinement of this framework may be necessary because single molecule experiments indicate that there is a great dispersion in the time scales governing the dynamics of the chaperonin cycle. \u003C\u002Fjats:p>",{"EN":43},"Chaperonin-Mediated Protein Folding",{"VOID":45},"11340060",{"VOID":47},"10.1146\u002Fannurev.biophys.30.1.245","PUBLICATION","VERIFIED","Auto Verify",[52],"EN","https:\u002F\u002Fwww.annualreviews.org\u002Fdoi\u002F10.1146\u002Fannurev.biophys.30.1.245",[55,78],{"id":56,"sortIndex":57,"researcher":20,"roles":58,"affiliations":59,"properties":71},"66bbd69d-63f9-4449-a67a-eacc9b0d23ab",1,[],[60],{"id":61,"sortIndex":21,"affiliation":62,"properties":20},"2905c47d-bb4f-489b-a2f8-de2e034a3092",{"id":63,"createTime":64,"updateTime":64,"relativeEntities":65,"slug":66,"properties":67,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"d4dd0603-59e1-4842-a93d-d3a695df9ccd","2024-09-18T23:57:17.020+00:00",[],"Center-for-Biomolecular-Structure-and-Organization-Department-of-Chemistry-and-Biochemistry-University-of-Maryland-Collge-Park-Maryland-20742-",{"title":68},{"EN":69},"Center for Biomolecular Structure and Organization, Department of Chemistry and Biochemistry, University of Maryland, Collge Park, Maryland 20742;","AFFILIATION",{"openalex":72,"orcid":74,"title":76},{"VOID":73},"A5054928202",{"VOID":75},"https:\u002F\u002Forcid.org\u002F0000-0003-2805-8792",{"EN":77},"George H. Lorimer",{"id":79,"sortIndex":21,"researcher":20,"roles":80,"affiliations":81,"properties":88},"ec96f465-31d0-4d50-9658-27424e6ce75d",[],[82],{"id":83,"sortIndex":21,"affiliation":84,"properties":20},"0479e37a-3196-4883-9687-16820b29624f",{"id":63,"createTime":64,"updateTime":64,"relativeEntities":85,"slug":66,"properties":86,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},[],{"title":87},{"EN":69},{"openalex":89,"orcid":91,"title":93},{"VOID":90},"A5036725653",{"VOID":92},"https:\u002F\u002Forcid.org\u002F0000-0003-1801-5924",{"EN":94},"D. Thirumalai","ARTICLE",{"url":20,"publisher":97,"properties":106},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":98,"slug":10,"properties":99,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":103,"manageAffiliations":104,"indexDatabases":105,"url":20,"thumbnailPath":20,"statistic":20,"gsStatistic":20,"type":20,"analyzePriority":20},[],{"issn":100,"eissn":101,"title":102},{"VOID":13},{"VOID":15},{"EN":17},[],[],[],{"volume":107,"pages":109,"issue":111},{"VOID":108},"30",{"VOID":110},"245-269",{"VOID":112},"1",406,{"total":113,"publishYear":20,"statisticByYear":115},{"2012":116,"2013":117,"2014":118,"2015":119,"2016":120,"2017":120,"2018":121,"2019":122,"2020":121,"2021":116,"2022":123,"2023":124,"2024":122},15,22,19,14,16,11,8,17,4,"2001-06-01",2001,[128,131,134,137,140,143,146,149,152,155,158,161,164,167,170,173,176,179,182,185,189,192,196,199,202,205,208,211,214,217,220,223,226,229,232,235,238,241,244,247,250,253,257,260,263,266,269,272,276,279,282,285,288,291,294,297,300,303,306,309,312,315,318,321,324,327,330,333,336,339,342,345,348,351,354,357],{"id":20,"text":129,"url":20,"identifiers":130},"10.1074\u002Fjbc.275.18.13755",{"doi":129},{"id":20,"text":132,"url":20,"identifiers":133},"10.1074\u002Fjbc.272.51.32158",{"doi":132},{"id":20,"text":135,"url":20,"identifiers":136},"10.1006\u002Fjmbi.1999.2591",{"doi":135},{"id":20,"text":138,"url":20,"identifiers":139},"10.1038\u002F371578a0",{"doi":138},{"id":20,"text":141,"url":20,"identifiers":142},"10.1002\u002F(SICI)1097-0134(199603)24:3\u003C345::AID-PROT7>3.0.CO;2-F",{"doi":141},{"id":20,"text":144,"url":20,"identifiers":145},"10.1006\u002Fjmbi.1999.3040",{"doi":144},{"id":20,"text":147,"url":20,"identifiers":148},"10.1016\u002FS0092-8674(00)81673-6",{"doi":147},{"id":20,"text":150,"url":20,"identifiers":151},"10.1006\u002Fjmbi.1998.2403",{"doi":150},{"id":20,"text":153,"url":20,"identifiers":154},"10.1006\u002Fjmbi.1999.3138",{"doi":153},{"id":20,"text":156,"url":20,"identifiers":157},"10.1073\u002Fpnas.93.9.4509",{"doi":156},{"id":20,"text":159,"url":20,"identifiers":160},"10.1038\u002Fnsb0197-10",{"doi":159},{"id":20,"text":162,"url":20,"identifiers":163},"10.1021\u002Far9700825",{"doi":162},{"id":20,"text":165,"url":20,"identifiers":166},"10.1016\u002FS0092-8674(00)80509-7",{"doi":165},{"id":20,"text":168,"url":20,"identifiers":169},"10.1016\u002FS0092-8674(00)80692-3",{"doi":168},{"id":20,"text":171,"url":20,"identifiers":172},"10.1007\u002FBF00333274",{"doi":171},{"id":20,"text":174,"url":20,"identifiers":175},"10.1006\u002Fjmbi.1997.1007",{"doi":174},{"id":20,"text":177,"url":20,"identifiers":178},"10.1002\u002Fpro.5560060401",{"doi":177},{"id":20,"text":180,"url":20,"identifiers":181},"10.1038\u002F371614a0",{"doi":180},{"id":20,"text":183,"url":20,"identifiers":184},"10.1016\u002FS0959-440X(97)80002-4",{"doi":183},{"id":20,"text":186,"url":20,"identifiers":187},"Fisher MT, 1994, J. Biol. Chem., 269, 13629, 10.1016\u002FS0021-9258(17)36876-X",{"doi":188},"10.1016\u002FS0021-9258(17)36876-X",{"id":20,"text":190,"url":20,"identifiers":191},"Fisher TE, 2000, Nat. Struct. Biol., 9, 719",{},{"id":20,"text":193,"url":20,"identifiers":194},"Gordon CL, 1994, J. Biol. Chem., 269, 27941, 10.1016\u002FS0021-9258(18)46878-0",{"doi":195},"10.1016\u002FS0021-9258(18)46878-0",{"id":20,"text":197,"url":20,"identifiers":198},"10.1074\u002Fjbc.M002243200",{"doi":197},{"id":20,"text":200,"url":20,"identifiers":201},"10.1006\u002Fjmbi.1993.1471",{"doi":200},{"id":20,"text":203,"url":20,"identifiers":204},"10.1073\u002Fpnas.91.20.9292",{"doi":203},{"id":20,"text":206,"url":20,"identifiers":207},"10.1002\u002Fbip.360360108",{"doi":206},{"id":20,"text":209,"url":20,"identifiers":210},"10.1006\u002Fbulm.1999.0150",{"doi":209},{"id":20,"text":212,"url":20,"identifiers":213},"10.1038\u002F45977",{"doi":212},{"id":20,"text":215,"url":20,"identifiers":216},"10.1021\u002Fbi9714870",{"doi":215},{"id":20,"text":218,"url":20,"identifiers":219},"10.1021\u002Fbi00044a037",{"doi":218},{"id":20,"text":221,"url":20,"identifiers":222},"10.1006\u002Fjmbi.1996.0666",{"doi":221},{"id":20,"text":224,"url":20,"identifiers":225},"10.1021\u002Fbi00865a047",{"doi":224},{"id":20,"text":227,"url":20,"identifiers":228},"10.1074\u002Fjbc.270.3.1011",{"doi":227},{"id":20,"text":230,"url":20,"identifiers":231},"10.1096\u002Ffasebj.10.1.8566548",{"doi":230},{"id":20,"text":233,"url":20,"identifiers":234},"10.1038\u002F41892",{"doi":233},{"id":20,"text":236,"url":20,"identifiers":237},"10.1073\u002Fpnas.95.15.8502",{"doi":236},{"id":20,"text":239,"url":20,"identifiers":240},"10.1006\u002Fjmbi.2000.4014",{"doi":239},{"id":20,"text":242,"url":20,"identifiers":243},"10.1016\u002FS0022-2836(65)80285-6",{"doi":242},{"id":20,"text":245,"url":20,"identifiers":246},"10.1038\u002F36626",{"doi":245},{"id":20,"text":248,"url":20,"identifiers":249},"10.1006\u002Fjmbi.1997.1192",{"doi":248},{"id":20,"text":251,"url":20,"identifiers":252},"10.1023\u002FA:1011541917701",{"doi":251},{"id":20,"text":254,"url":20,"identifiers":255},"Nielsen KL, 1999, J. Bacteriol., 181, 5871, 10.1128\u002FJB.181.18.5871-5875.1999",{"doi":256},"10.1128\u002FJB.181.18.5871-5875.1999",{"id":20,"text":258,"url":20,"identifiers":259},"10.1146\u002Fannurev.physchem.48.1.545",{"doi":258},{"id":20,"text":261,"url":20,"identifiers":262},"10.1051\u002Fjp1:1997174",{"doi":261},{"id":20,"text":264,"url":20,"identifiers":265},"10.1006\u002Fbbrc.1999.1864",{"doi":264},{"id":20,"text":267,"url":20,"identifiers":268},"10.1006\u002Fjmbi.1997.1081",{"doi":267},{"id":20,"text":270,"url":20,"identifiers":271},"10.1016\u002FS0968-0004(98)01193-1",{"doi":270},{"id":20,"text":273,"url":20,"identifiers":274},"Richarme G, 1994, J. Biol. Chem., 269, 7095, 10.1016\u002FS0021-9258(17)37251-4",{"doi":275},"10.1016\u002FS0021-9258(17)37251-4",{"id":20,"text":277,"url":20,"identifiers":278},"10.1038\u002F42047",{"doi":277},{"id":20,"text":280,"url":20,"identifiers":281},"10.1016\u002FS0092-8674(00)80742-4",{"doi":280},{"id":20,"text":283,"url":20,"identifiers":284},"10.1016\u002FS0959-440X(00)00074-9",{"doi":283},{"id":20,"text":286,"url":20,"identifiers":287},"10.1074\u002Fjbc.274.30.21251",{"doi":286},{"id":20,"text":289,"url":20,"identifiers":290},"10.1038\u002Fnsb0598-385",{"doi":289},{"id":20,"text":292,"url":20,"identifiers":293},"10.1126\u002Fscience.284.5415.822",{"doi":292},{"id":20,"text":295,"url":20,"identifiers":296},"10.1146\u002Fannurev.biochem.67.1.581",{"doi":295},{"id":20,"text":298,"url":20,"identifiers":299},"10.1007\u002F978-1-4899-1349-4_12",{"doi":298},{"id":20,"text":301,"url":20,"identifiers":302},"10.1051\u002Fjp1:1995209",{"doi":301},{"id":20,"text":304,"url":20,"identifiers":305},"Thirumalai D, 1997, Theor. Chem. Acc., 1, 23",{},{"id":20,"text":307,"url":20,"identifiers":308},"10.1073\u002Fpnas.93.9.4030",{"doi":307},{"id":20,"text":310,"url":20,"identifiers":311},"10.1126\u002Fscience.7913555",{"doi":310},{"id":20,"text":313,"url":20,"identifiers":314},"10.1038\u002F342451a0",{"doi":313},{"id":20,"text":316,"url":20,"identifiers":317},"10.1038\u002F77936",{"doi":316},{"id":20,"text":319,"url":20,"identifiers":320},"10.1002\u002Fpro.5560010308",{"doi":319},{"id":20,"text":322,"url":20,"identifiers":323},"10.1016\u002FS0006-3495(98)78032-4",{"doi":322},{"id":20,"text":325,"url":20,"identifiers":326},"10.1073\u002Fpnas.93.18.9425",{"doi":325},{"id":20,"text":328,"url":20,"identifiers":329},"10.1016\u002F0092-8674(94)90533-9",{"doi":328},{"id":20,"text":331,"url":20,"identifiers":332},"10.1016\u002FS0092-8674(00)81293-3",{"doi":331},{"id":20,"text":334,"url":20,"identifiers":335},"10.1038\u002Fnsb0997-690",{"doi":334},{"id":20,"text":337,"url":20,"identifiers":338},"10.1021\u002Fbi991765q",{"doi":337},{"id":20,"text":340,"url":20,"identifiers":341},"10.1038\u002F41944",{"doi":340},{"id":20,"text":343,"url":20,"identifiers":344},"10.1006\u002Fjsbi.1998.4060",{"doi":343},{"id":20,"text":346,"url":20,"identifiers":347},"10.1006\u002Fjmbi.1996.0028",{"doi":346},{"id":20,"text":349,"url":20,"identifiers":350},"10.1021\u002Fbi00016a001",{"doi":349},{"id":20,"text":352,"url":20,"identifiers":353},"10.1021\u002Fbi980370o",{"doi":352},{"id":20,"text":355,"url":20,"identifiers":356},"10.1073\u002Fpnas.040449997",{"doi":355},{"id":20,"text":358,"url":20,"identifiers":359},"10.1126\u002Fscience.271.5249.642",{"doi":358},false,{"id":362,"createTime":363,"updateTime":363,"relativeEntities":364,"slug":365,"properties":366,"entityType":48,"verifyStatus":19,"verifyTime":363,"verifyNote":379,"syncStatus":19,"languages":380,"translateLanguages":20,"viewCount":21,"primaryUrl":381,"fullTextUrl":20,"authors":382,"publicationType":95,"publisherRelationship":413,"citationCount":429,"citationInfo":430,"publishDate":444,"publishYear":445,"citationAnalyzeStatus":19,"lastCitationAnalyze":20,"indexDatabases":20,"openAccess":20,"references":446,"isForceReanalyzing":360},"5728497a-052b-4a64-a7b1-59ce517b6c03","2024-09-27T23:56:19.525+00:00",[],"Macromolecular-Crowding-Biochemical-Biophysical-and-Physiological-Consequences",{"mag":367,"keywords":369,"openalex":370,"abstract":372,"title":373,"pm":375,"doi":377},{"VOID":368},"2165360511",{},{"VOID":371},"W2165360511",{},{"EN":374},"Macromolecular Crowding: Biochemical, Biophysical, and Physiological Consequences",{"VOID":376},"7688609",{"VOID":378},"10.1146\u002Fannurev.bb.22.060193.000331","Author affiliation is blank",[52],"https:\u002F\u002Fwww.annualreviews.org\u002Fdoi\u002F10.1146\u002Fannurev.bb.22.060193.000331",[383,394],{"id":384,"sortIndex":57,"researcher":20,"roles":385,"affiliations":386,"properties":387},"90805472-eb05-4894-8873-62ee18aca2af",[],[],{"openalex":388,"orcid":390,"title":392},{"VOID":389},"A5038365714",{"VOID":391},"https:\u002F\u002Forcid.org\u002F0000-0001-8459-1247",{"EN":393},"Allen P. Minton",{"id":395,"sortIndex":21,"researcher":20,"roles":396,"affiliations":397,"properties":408},"db21dd6f-6e1a-4713-9f6c-18433ad339c4",[],[398],{"id":399,"sortIndex":21,"affiliation":400,"properties":20},"2971917d-ada9-4c6b-857e-20e844039cc9",{"id":401,"createTime":402,"updateTime":402,"relativeEntities":403,"slug":404,"properties":405,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"cf0f38a2-0696-4da6-8bdc-a282406d4a70","2024-09-27T23:56:19.539+00:00",[],"Section-on-Physical-Chemistry-National-Institute-of-Diabetes-and-Digestive-and-Kidney-Diseases-National-Institutes-of-Health-Bethesda-Maryland-20892-",{"title":406},{"EN":407},"Section on Physical Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892.",{"openalex":409,"title":411},{"VOID":410},"A5054245320",{"EN":412},"Steven B. Zimmerman",{"url":20,"publisher":414,"properties":423},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":415,"slug":10,"properties":416,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":420,"manageAffiliations":421,"indexDatabases":422,"url":20,"thumbnailPath":20,"statistic":20,"gsStatistic":20,"type":20,"analyzePriority":20},[],{"issn":417,"eissn":418,"title":419},{"VOID":13},{"VOID":15},{"EN":17},[],[],[],{"volume":424,"pages":426,"issue":428},{"VOID":425},"22",{"VOID":427},"27-65",{"VOID":112},1463,{"total":429,"publishYear":20,"statisticByYear":431},{"2012":432,"2013":433,"2014":434,"2015":435,"2016":436,"2017":437,"2018":438,"2019":439,"2020":432,"2021":440,"2022":441,"2023":442,"2024":443},63,77,83,76,65,67,50,60,61,43,39,34,"1993-06-01",1993,[],{"id":448,"createTime":449,"updateTime":449,"relativeEntities":450,"slug":451,"properties":452,"entityType":48,"verifyStatus":49,"verifyTime":466,"verifyNote":50,"syncStatus":19,"languages":467,"translateLanguages":20,"viewCount":21,"primaryUrl":468,"fullTextUrl":20,"authors":469,"publicationType":95,"publisherRelationship":492,"citationCount":508,"citationInfo":509,"publishDate":522,"publishYear":523,"citationAnalyzeStatus":19,"lastCitationAnalyze":20,"indexDatabases":20,"openAccess":20,"references":524,"isForceReanalyzing":360},"cb279d94-fb7e-4836-8887-13c200451ed4","2024-09-27T23:31:01.406+00:00",[],"The-State-of-Lipid-Rafts-From-Model-Membranes-to-Cells",{"mag":453,"keywords":455,"openalex":456,"abstract":458,"title":460,"pm":462,"doi":464},{"VOID":454},"2122882997",{},{"VOID":457},"W2122882997",{"EN":459},"\u003Cjats:p>▪ Abstract  Lipid raft microdomains were conceived as part of a mechanism for the intracellular trafficking of lipids and lipid-anchored proteins. The raft hypothesis is based on the behavior of defined lipid mixtures in liposomes and other model membranes. Experiments in these well-characterized systems led to operational definitions for lipid rafts in cell membranes. These definitions, detergent solubility to define components of rafts, and sensitivity to cholesterol deprivation to define raft functions implicated sphingolipid- and cholesterol-rich lipid rafts in many cell functions. Despite extensive work, the basis for raft formation in cell membranes and the size of rafts and their stability are all uncertain. Recent work converges on very small rafts <10 nm in diameter that may enlarge and stabilize when their constituents are cross-linked.\u003C\u002Fjats:p>",{"EN":461},"The State of Lipid Rafts: From Model Membranes to Cells",{"VOID":463},"12543707",{"VOID":465},"10.1146\u002Fannurev.biophys.32.110601.142439","2024-09-27T23:31:01.405+00:00",[52],"https:\u002F\u002Fwww.annualreviews.org\u002Fdoi\u002F10.1146\u002Fannurev.biophys.32.110601.142439",[470],{"id":471,"sortIndex":21,"researcher":20,"roles":472,"affiliations":473,"properties":485},"1a077991-9c76-4b96-bc54-23e755ec02f3",[],[474],{"id":475,"sortIndex":21,"affiliation":476,"properties":20},"8b59d4fd-27a0-44bf-b972-313958b61aa3",{"id":477,"createTime":478,"updateTime":479,"relativeEntities":480,"slug":481,"properties":482,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"1e66e232-2948-4714-a989-3b12c9639080","2024-01-10T04:43:13.087+00:00","2024-09-27T23:31:01.421+00:00",[],"Biology-Department-The-Johns-Hopkins-University-Baltimore-Maryland-21218-USA",{"title":483},{"VI":484},"Biology Department, The Johns Hopkins University, Baltimore, Maryland 21218, USA",{"openalex":486,"orcid":488,"title":490},{"VOID":487},"A5012850937",{"VOID":489},"https:\u002F\u002Forcid.org\u002F0000-0003-4930-1739",{"EN":491},"Michael Edidin",{"url":20,"publisher":493,"properties":502},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":494,"slug":10,"properties":495,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":499,"manageAffiliations":500,"indexDatabases":501,"url":20,"thumbnailPath":20,"statistic":20,"gsStatistic":20,"type":20,"analyzePriority":20},[],{"issn":496,"eissn":497,"title":498},{"VOID":13},{"VOID":15},{"EN":17},[],[],[],{"volume":503,"pages":505,"issue":507},{"VOID":504},"32",{"VOID":506},"257-283",{"VOID":112},1328,{"total":508,"publishYear":20,"statisticByYear":510},{"2012":511,"2013":512,"2014":513,"2015":514,"2016":515,"2017":516,"2018":517,"2019":518,"2020":117,"2021":519,"2022":116,"2023":520,"2024":521},59,47,42,51,37,35,28,26,18,31,9,"2003-06-01",2003,[525,528,531,534,537,540,543,546,549,552,555,558,561,564,567,570,574,577,580,583,587,590,594,597,600,603,606,609,612,615,618,621,625,628,631,634,637,640,643,646,649,652,655,658,661,664,667,670,673,677,680,683,686,689,692,695,698,701,704,707,710,713,716,720,723,726,729,732,735,738,741,744,747,751,754,757,760,763,766,769,772,775,778,781,784,787,790,793,796,799,802,805,808,811,814,817,820,823,826,829,832,835,838,841,844,847,850,853,856,859,862,865,868,871,874,877,880,883,886,889,892,895,898,901,904,907,910,913,916,919,922,925,928,931,935,938,941,944,947,950,953,956,959,962,965,968,971,974,977,980,983,986],{"id":20,"text":526,"url":20,"identifiers":527},"10.1146\u002Fannurev.biochem.67.1.199",{"doi":526},{"id":20,"text":529,"url":20,"identifiers":530},"10.1126\u002Fscience.1068886",{"doi":529},{"id":20,"text":532,"url":20,"identifiers":533},"10.1016\u002FS0006-3495(01)75920-6",{"doi":532},{"id":20,"text":535,"url":20,"identifiers":536},"10.1016\u002FS0006-3495(00)76592-1",{"doi":535},{"id":20,"text":538,"url":20,"identifiers":539},"10.1016\u002FS1074-7613(01)00223-0",{"doi":538},{"id":20,"text":541,"url":20,"identifiers":542},"10.1002\u002Feji.1830220104",{"doi":541},{"id":20,"text":544,"url":20,"identifiers":545},"10.1016\u002F0009-3084(95)02455-R",{"doi":544},{"id":20,"text":547,"url":20,"identifiers":548},"10.1084\u002Fjem.20011500",{"doi":547},{"id":20,"text":550,"url":20,"identifiers":551},"10.1021\u002Fbi0156714",{"doi":550},{"id":20,"text":553,"url":20,"identifiers":554},"10.1016\u002FS0165-2478(96)02677-6",{"doi":553},{"id":20,"text":556,"url":20,"identifiers":557},"10.1016\u002F0304-4157(87)90017-7",{"doi":556},{"id":20,"text":559,"url":20,"identifiers":560},"10.1083\u002Fjcb.151.7.1353",{"doi":559},{"id":20,"text":562,"url":20,"identifiers":563},"Boyle R. 1964.The Sceptical Chymist (1661), ed. EO Moelwyn-Hughs, p. 63. London: Dent",{},{"id":20,"text":565,"url":20,"identifiers":566},"10.1126\u002Fscience.2571189",{"doi":565},{"id":20,"text":568,"url":20,"identifiers":569},"10.1016\u002F0092-8674(92)90189-J",{"doi":568},{"id":20,"text":571,"url":20,"identifiers":572},"Brown RE, 1998, J. Cell Sci., 111, 1, 10.1242\u002Fjcs.111.1.1",{"doi":573},"10.1242\u002Fjcs.111.1.1",{"id":20,"text":575,"url":20,"identifiers":576},"10.1016\u002FS0006-3495(02)75394-0",{"doi":575},{"id":20,"text":578,"url":20,"identifiers":579},"10.1016\u002FS0005-2736(02)00505-9",{"doi":578},{"id":20,"text":581,"url":20,"identifiers":582},"10.1093\u002Femboj\u002F20.16.4332",{"doi":581},{"id":20,"text":584,"url":20,"identifiers":585},"Cerneus DP, 1993, J. Biol. Chem., 268, 3150, 10.1016\u002FS0021-9258(18)53671-1",{"doi":586},"10.1016\u002FS0021-9258(18)53671-1",{"id":20,"text":588,"url":20,"identifiers":589},"10.1093\u002Femboj\u002F20.7.1583",{"doi":588},{"id":20,"text":591,"url":20,"identifiers":592},"Cinek T, 1992, J. Immunol., 149, 2262, 10.4049\u002Fjimmunol.149.7.2262",{"doi":593},"10.4049\u002Fjimmunol.149.7.2262",{"id":20,"text":595,"url":20,"identifiers":596},"10.1021\u002Fbi00511a019",{"doi":595},{"id":20,"text":598,"url":20,"identifiers":599},"10.1016\u002FS0006-3495(01)76114-0",{"doi":598},{"id":20,"text":601,"url":20,"identifiers":602},"10.1073\u002Fpnas.191168698",{"doi":601},{"id":20,"text":604,"url":20,"identifiers":605},"10.1093\u002Femboj\u002F21.8.1899",{"doi":604},{"id":20,"text":607,"url":20,"identifiers":608},"10.1016\u002FS0092-8674(02)00820-6",{"doi":607},{"id":20,"text":610,"url":20,"identifiers":611},"10.1021\u002Fbi00117a035",{"doi":610},{"id":20,"text":613,"url":20,"identifiers":614},"10.1016\u002FS1388-1981(00)00150-5",{"doi":613},{"id":20,"text":616,"url":20,"identifiers":617},"10.1021\u002Fbi9828324",{"doi":616},{"id":20,"text":619,"url":20,"identifiers":620},"10.1016\u002FS0006-3495(02)75501-X",{"doi":619},{"id":20,"text":622,"url":20,"identifiers":623},"Garcia M, 1993, J. Cell Sci., 104, 1281, 10.1242\u002Fjcs.104.4.1281",{"doi":624},"10.1242\u002Fjcs.104.4.1281",{"id":20,"text":626,"url":20,"identifiers":627},"10.1074\u002Fjbc.R100025200",{"doi":626},{"id":20,"text":629,"url":20,"identifiers":630},"10.1091\u002Fmbc.12.6.1819",{"doi":629},{"id":20,"text":632,"url":20,"identifiers":633},"10.1016\u002FS0006-3495(86)83714-6",{"doi":632},{"id":20,"text":635,"url":20,"identifiers":636},"10.1016\u002F0167-4889(82)90010-6",{"doi":635},{"id":20,"text":638,"url":20,"identifiers":639},"10.1083\u002Fjcb.133.6.1265",{"doi":638},{"id":20,"text":641,"url":20,"identifiers":642},"10.1074\u002Fjbc.M102667200",{"doi":641},{"id":20,"text":644,"url":20,"identifiers":645},"10.1073\u002Fpnas.231377398",{"doi":644},{"id":20,"text":647,"url":20,"identifiers":648},"10.1091\u002Fmbc.8.3.533",{"doi":647},{"id":20,"text":650,"url":20,"identifiers":651},"10.1083\u002Fjcb.141.4.929",{"doi":650},{"id":20,"text":653,"url":20,"identifiers":654},"10.1002\u002F(SICI)1521-4141(199902)29:02\u003C556::AID-IMMU556>3.0.CO;2-2",{"doi":653},{"id":20,"text":656,"url":20,"identifiers":657},"10.1021\u002Fbi992125q",{"doi":656},{"id":20,"text":659,"url":20,"identifiers":660},"10.1099\u002F0022-1317-78-8-1907",{"doi":659},{"id":20,"text":662,"url":20,"identifiers":663},"10.1016\u002FS0006-3495(02)75278-8",{"doi":662},{"id":20,"text":665,"url":20,"identifiers":666},"10.1074\u002Fjbc.M200576200",{"doi":665},{"id":20,"text":668,"url":20,"identifiers":669},"10.1016\u002F0021-9797(77)90270-3",{"doi":668},{"id":20,"text":671,"url":20,"identifiers":672},"10.1016\u002F0014-4827(85)90278-2",{"doi":671},{"id":20,"text":674,"url":20,"identifiers":675},"Holowka D, 2000, J. Cell Sci., 113, 1009, 10.1242\u002Fjcs.113.6.1009",{"doi":676},"10.1242\u002Fjcs.113.6.1009",{"id":20,"text":678,"url":20,"identifiers":679},"10.1042\u002Fbj2500865",{"doi":678},{"id":20,"text":681,"url":20,"identifiers":682},"10.1016\u002FS0955-0674(00)00191-5",{"doi":681},{"id":20,"text":684,"url":20,"identifiers":685},"10.1016\u002F0005-2736(87)90020-4",{"doi":684},{"id":20,"text":687,"url":20,"identifiers":688},"10.1016\u002FS0070-2161(08)60857-6",{"doi":687},{"id":20,"text":690,"url":20,"identifiers":691},"10.1016\u002FB978-0-12-024915-2.50007-4",{"doi":690},{"id":20,"text":693,"url":20,"identifiers":694},"10.1083\u002Fjcb.147.2.447",{"doi":693},{"id":20,"text":696,"url":20,"identifiers":697},"10.1016\u002FS0009-3084(99)00058-4",{"doi":696},{"id":20,"text":699,"url":20,"identifiers":700},"10.1002\u002F1521-4141(200003)30:3\u003C954::AID-IMMU954>3.3.CO;2-P",{"doi":699},{"id":20,"text":702,"url":20,"identifiers":703},"10.1016\u002FS0006-3495(01)76053-5",{"doi":702},{"id":20,"text":705,"url":20,"identifiers":706},"10.1002\u002Fj.1460-2075.1992.tb05124.x",{"doi":705},{"id":20,"text":708,"url":20,"identifiers":709},"10.1103\u002FPhysRevLett.81.5019",{"doi":708},{"id":20,"text":711,"url":20,"identifiers":712},"10.1083\u002Fjcb.142.1.69",{"doi":711},{"id":20,"text":714,"url":20,"identifiers":715},"Kenworthy AK, 2001, Mol. Biol. Cell, 12, 471",{},{"id":20,"text":717,"url":20,"identifiers":718},"Klausner RD, 1980, J. Biol. Chem., 255, 1286, 10.1016\u002FS0021-9258(19)86027-1",{"doi":719},"10.1016\u002FS0021-9258(19)86027-1",{"id":20,"text":721,"url":20,"identifiers":722},"10.1073\u002Fpnas.96.15.8461",{"doi":721},{"id":20,"text":724,"url":20,"identifiers":725},"Kwik Margolis, 2002, Mol. Biol. Cell, 13, 142",{},{"id":20,"text":727,"url":20,"identifiers":728},"10.1093\u002Femboj\u002F20.9.2202",{"doi":727},{"id":20,"text":730,"url":20,"identifiers":731},"10.1016\u002F0962-8924(96)10033-7",{"doi":730},{"id":20,"text":733,"url":20,"identifiers":734},"10.1021\u002Fbi011579w",{"doi":733},{"id":20,"text":736,"url":20,"identifiers":737},"10.1021\u002Fbi012038+",{"doi":736},{"id":20,"text":739,"url":20,"identifiers":740},"10.1083\u002Fjcb.109.5.2145",{"doi":739},{"id":20,"text":742,"url":20,"identifiers":743},"10.1073\u002Fpnas.85.24.9557",{"doi":742},{"id":20,"text":745,"url":20,"identifiers":746},"10.1016\u002FS0959-440X(02)00351-2",{"doi":745},{"id":20,"text":748,"url":20,"identifiers":749},"Los DA, Murata N. 2000. Regulation of enzymatic activity and gene expression by membrane fluidity.Science's STKEhttp:\u002F\u002Fwww.stke.org\u002Fcgi\u002Fcontent\u002Ffull\u002FOC_sigtrans;2000\u002F62\u002Fpe1",{"doi":750},"10.1126\u002Fstke.2000.62.pe1",{"id":20,"text":752,"url":20,"identifiers":753},"10.1016\u002FS0006-3495(01)76057-2",{"doi":752},{"id":20,"text":755,"url":20,"identifiers":756},"10.1074\u002Fjbc.M111679200",{"doi":755},{"id":20,"text":758,"url":20,"identifiers":759},"10.1016\u002FS0006-3495(01)75913-9",{"doi":758},{"id":20,"text":761,"url":20,"identifiers":762},"10.1016\u002FS0304-4157(98)00009-4",{"doi":761},{"id":20,"text":764,"url":20,"identifiers":765},"10.1016\u002FS0005-2736(00)00344-8",{"doi":764},{"id":20,"text":767,"url":20,"identifiers":768},"10.1021\u002Fbi015718l",{"doi":767},{"id":20,"text":770,"url":20,"identifiers":771},"10.1093\u002Femboj\u002F17.16.4626",{"doi":770},{"id":20,"text":773,"url":20,"identifiers":774},"10.1091\u002Fmbc.12.11.3601",{"doi":773},{"id":20,"text":776,"url":20,"identifiers":777},"10.1146\u002Fannurev.biophys.32.110601.141704",{"doi":776},{"id":20,"text":779,"url":20,"identifiers":780},"10.1146\u002Fannurev.biophys.31.082901.134259",{"doi":779},{"id":20,"text":782,"url":20,"identifiers":783},"10.1016\u002FS0006-3495(02)75497-0",{"doi":782},{"id":20,"text":785,"url":20,"identifiers":786},"10.1074\u002Fjbc.C100654200",{"doi":785},{"id":20,"text":788,"url":20,"identifiers":789},"10.1083\u002Fjcb.144.6.1271",{"doi":788},{"id":20,"text":791,"url":20,"identifiers":792},"10.1128\u002FJVI.74.7.3264-3272.2000",{"doi":791},{"id":20,"text":794,"url":20,"identifiers":795},"10.1083\u002Fjcb.153.3.529",{"doi":794},{"id":20,"text":797,"url":20,"identifiers":798},"10.1083\u002Fjcb.200202009",{"doi":797},{"id":20,"text":800,"url":20,"identifiers":801},"10.1021\u002Fla001263+",{"doi":800},{"id":20,"text":803,"url":20,"identifiers":804},"10.1016\u002FS0005-2760(97)00126-4",{"doi":803},{"id":20,"text":806,"url":20,"identifiers":807},"10.1016\u002FS0163-7827(01)00020-0",{"doi":806},{"id":20,"text":809,"url":20,"identifiers":810},"10.1074\u002Fjbc.274.48.34459",{"doi":809},{"id":20,"text":812,"url":20,"identifiers":813},"10.1016\u002F0005-2736(76)90316-3",{"doi":812},{"id":20,"text":815,"url":20,"identifiers":816},"10.1038\u002Fnri726",{"doi":815},{"id":20,"text":818,"url":20,"identifiers":819},"10.1021\u002Fbi025943i",{"doi":818},{"id":20,"text":821,"url":20,"identifiers":822},"10.1021\u002Fbi0156557",{"doi":821},{"id":20,"text":824,"url":20,"identifiers":825},"10.1074\u002Fjbc.273.35.22298",{"doi":824},{"id":20,"text":827,"url":20,"identifiers":828},"10.1042\u002Fbj3080269",{"doi":827},{"id":20,"text":830,"url":20,"identifiers":831},"10.1083\u002Fjcb.148.5.997",{"doi":830},{"id":20,"text":833,"url":20,"identifiers":834},"Prior IA, 2001, Nat. Cell, 3, 868",{},{"id":20,"text":836,"url":20,"identifiers":837},"10.1083\u002Fjcb.200102084",{"doi":836},{"id":20,"text":839,"url":20,"identifiers":840},"10.1016\u002FS0006-3495(01)76185-1",{"doi":839},{"id":20,"text":842,"url":20,"identifiers":843},"10.1073\u002Fpnas.220418097",{"doi":842},{"id":20,"text":845,"url":20,"identifiers":846},"10.1016\u002FS0092-8674(00)81560-3",{"doi":845},{"id":20,"text":848,"url":20,"identifiers":849},"10.1016\u002FS0304-4157(98)00019-7",{"doi":848},{"id":20,"text":851,"url":20,"identifiers":852},"10.1016\u002FS0014-5793(01)02636-9",{"doi":851},{"id":20,"text":854,"url":20,"identifiers":855},"10.1021\u002Fbi00488a040",{"doi":854},{"id":20,"text":857,"url":20,"identifiers":858},"10.1091\u002Fmbc.10.4.961",{"doi":857},{"id":20,"text":860,"url":20,"identifiers":861},"10.1006\u002Fexcr.2001.5253",{"doi":860},{"id":20,"text":863,"url":20,"identifiers":864},"10.1073\u002Fpnas.75.10.5071",{"doi":863},{"id":20,"text":866,"url":20,"identifiers":867},"10.1083\u002Fjcb.111.6.2931",{"doi":866},{"id":20,"text":869,"url":20,"identifiers":870},"10.1016\u002FS1534-5807(02)00145-4",{"doi":869},{"id":20,"text":872,"url":20,"identifiers":873},"10.1016\u002FS0006-3495(01)75803-1",{"doi":872},{"id":20,"text":875,"url":20,"identifiers":876},"10.1006\u002Fjmbi.2001.5322",{"doi":875},{"id":20,"text":878,"url":20,"identifiers":879},"10.1021\u002Fbi00499a015",{"doi":878},{"id":20,"text":881,"url":20,"identifiers":882},"10.1074\u002Fjbc.M204669200",{"doi":881},{"id":20,"text":884,"url":20,"identifiers":885},"10.1021\u002Fbi025625j",{"doi":884},{"id":20,"text":887,"url":20,"identifiers":888},"10.1074\u002Fjbc.274.4.2038",{"doi":887},{"id":20,"text":890,"url":20,"identifiers":891},"10.1016\u002F0005-2736(91)90185-B",{"doi":890},{"id":20,"text":893,"url":20,"identifiers":894},"10.1073\u002Fpnas.91.25.12130",{"doi":893},{"id":20,"text":896,"url":20,"identifiers":897},"10.1021\u002Fbi00011a039",{"doi":896},{"id":20,"text":899,"url":20,"identifiers":900},"10.1074\u002Fjbc.M210457200",{"doi":899},{"id":20,"text":902,"url":20,"identifiers":903},"10.1083\u002Fjcb.145.4.877",{"doi":902},{"id":20,"text":905,"url":20,"identifiers":906},"10.1073\u002Fpnas.76.9.4438",{"doi":905},{"id":20,"text":908,"url":20,"identifiers":909},"10.1038\u002F42408",{"doi":908},{"id":20,"text":911,"url":20,"identifiers":912},"10.1038\u002F35036052",{"doi":911},{"id":20,"text":914,"url":20,"identifiers":915},"10.1021\u002Fbi00417a001",{"doi":914},{"id":20,"text":917,"url":20,"identifiers":918},"10.1126\u002Fscience.175.4023.720",{"doi":917},{"id":20,"text":920,"url":20,"identifiers":921},"10.1016\u002F0009-3084(74)90065-6",{"doi":920},{"id":20,"text":923,"url":20,"identifiers":924},"10.1021\u002Fla011381c",{"doi":923},{"id":20,"text":926,"url":20,"identifiers":927},"10.1016\u002F0005-2736(85)90101-4",{"doi":926},{"id":20,"text":929,"url":20,"identifiers":930},"10.4049\u002Fjimmunol.165.11.6020",{"doi":929},{"id":20,"text":932,"url":20,"identifiers":933},"Stefanova I, 1991, J. Immunol., 147, 1587, 10.4049\u002Fjimmunol.147.5.1587",{"doi":934},"10.4049\u002Fjimmunol.147.5.1587",{"id":20,"text":936,"url":20,"identifiers":937},"10.1126\u002Fscience.1719635",{"doi":936},{"id":20,"text":939,"url":20,"identifiers":940},"Stubbs CD, 1983, Essays Biochem., 19, 1",{},{"id":20,"text":942,"url":20,"identifiers":943},"10.1073\u002Fpnas.96.12.6775",{"doi":942},{"id":20,"text":945,"url":20,"identifiers":946},"Suzuki K, 2001, Mol. Biol. Cell, 12, 470",{},{"id":20,"text":948,"url":20,"identifiers":949},"10.1016\u002FS0006-3495(01)75866-3",{"doi":948},{"id":20,"text":951,"url":20,"identifiers":952},"10.1146\u002Fannurev.bb.14.060185.002045",{"doi":951},{"id":20,"text":954,"url":20,"identifiers":955},"10.1006\u002Fsmim.2000.0300",{"doi":954},{"id":20,"text":957,"url":20,"identifiers":958},"10.1002\u002Fj.1460-2075.1982.tb01258.x",{"doi":957},{"id":20,"text":960,"url":20,"identifiers":961},"10.1002\u002Fjcb.240360106",{"doi":960},{"id":20,"text":963,"url":20,"identifiers":964},"10.1038\u002F29563",{"doi":963},{"id":20,"text":966,"url":20,"identifiers":967},"Wadhera M, 2002, FASEB J., 16, A1178",{},{"id":20,"text":969,"url":20,"identifiers":970},"10.1021\u002Fbi0112311",{"doi":969},{"id":20,"text":972,"url":20,"identifiers":973},"10.1016\u002FS0006-3495(01)75919-X",{"doi":972},{"id":20,"text":975,"url":20,"identifiers":976},"10.1016\u002FS0304-4157(98)00012-4",{"doi":975},{"id":20,"text":978,"url":20,"identifiers":979},"10.1016\u002FS0962-8924(97)01130-6",{"doi":978},{"id":20,"text":981,"url":20,"identifiers":982},"10.1016\u002FS0952-7915(02)00339-4",{"doi":981},{"id":20,"text":984,"url":20,"identifiers":985},"10.1126\u002Fscience.1068539",{"doi":984},{"id":20,"text":987,"url":20,"identifiers":988},"10.1128\u002FJVI.74.10.4634-4644.2000",{"doi":987},{"id":990,"createTime":991,"updateTime":991,"relativeEntities":992,"slug":993,"properties":994,"entityType":48,"verifyStatus":49,"verifyTime":991,"verifyNote":50,"syncStatus":19,"languages":1007,"translateLanguages":20,"viewCount":21,"primaryUrl":1008,"fullTextUrl":20,"authors":1009,"publicationType":95,"publisherRelationship":1032,"citationCount":1048,"citationInfo":1049,"publishDate":1054,"publishYear":1055,"citationAnalyzeStatus":19,"lastCitationAnalyze":20,"indexDatabases":20,"openAccess":20,"references":1056,"isForceReanalyzing":360},"6ffdc1dd-9be5-49fc-acb0-a7cc2476498e","2024-08-30T21:46:08.605+00:00",[],"Conformational-Dynamics-of-the-Chromatin-Fiber-in-Solution-Determinants-Mechanisms-and-Functions",{"mag":995,"keywords":997,"openalex":998,"abstract":1000,"title":1001,"pm":1003,"doi":1005},{"VOID":996},"2140388293",{},{"VOID":999},"W2140388293",{},{"EN":1002},"Conformational Dynamics of the Chromatin Fiber in Solution: Determinants, Mechanisms, and Functions",{"VOID":1004},"11988475",{"VOID":1006},"10.1146\u002Fannurev.biophys.31.101101.140858",[52],"http:\u002F\u002Fwww.annualreviews.org\u002Fdoi\u002F10.1146\u002Fannurev.biophys.31.101101.140858",[1010],{"id":1011,"sortIndex":21,"researcher":20,"roles":1012,"affiliations":1013,"properties":1025},"0840a81e-3f73-4dca-8246-f6bc552a544f",[],[1014],{"id":1015,"sortIndex":21,"affiliation":1016,"properties":20},"bc6a1f18-d262-4714-a5c4-32596fd22dc5",{"id":1017,"createTime":1018,"updateTime":1019,"relativeEntities":1020,"slug":1021,"properties":1022,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"0785d03b-d1b0-475d-8879-93a3b06d6ea3","2024-08-30T21:46:08.615+00:00","2025-06-11T20:33:37.917+00:00",[],"Department-of-Biochemistry-The-University-of-Texas-Health-Science-Center-at-San-Antonio-7703-Floyd-Curl-Drive-Mail-Code-7760-San-Antonio-Texas-78229-3900-e-mail-",{"title":1023},{"EN":1024},"Department of Biochemistry, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, Mail Code 7760, San Antonio, Texas 78229-3900; e-mail:",{"openalex":1026,"orcid":1028,"title":1030},{"VOID":1027},"A5082281992",{"VOID":1029},"https:\u002F\u002Forcid.org\u002F0000-0002-3348-9071",{"EN":1031},"Jeffrey C. Hansen",{"url":20,"publisher":1033,"properties":1042},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1034,"slug":10,"properties":1035,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":1039,"manageAffiliations":1040,"indexDatabases":1041,"url":20,"thumbnailPath":20,"statistic":20,"gsStatistic":20,"type":20,"analyzePriority":20},[],{"issn":1036,"eissn":1037,"title":1038},{"VOID":13},{"VOID":15},{"EN":17},[],[],[],{"volume":1043,"pages":1045,"issue":1047},{"VOID":1044},"31",{"VOID":1046},"361-392",{"VOID":112},526,{"total":1048,"publishYear":20,"statisticByYear":1050},{"2012":1051,"2013":1052,"2014":116,"2015":519,"2016":1052,"2017":519,"2018":119,"2019":517,"2020":116,"2021":120,"2022":120,"2023":1053,"2024":122},32,20,10,"2002-06-01",2002,[1057,1060,1063,1066,1069,1072,1075,1078,1081,1084,1087,1090,1093,1096,1099,1102,1105,1108,1111,1114,1117,1120,1123,1126,1129,1132,1135,1138,1141,1144,1147,1150,1153,1156,1159,1162,1165,1168,1171,1174,1177,1180,1183,1186,1189,1192,1195,1198,1201,1204,1207,1210,1214,1217,1220,1223,1226,1229,1232,1235,1238,1241,1244,1248,1251,1255,1258,1261,1264,1267,1270,1273,1277,1280,1283,1286,1289,1292,1295,1298,1301,1304,1307,1310,1313,1316,1319,1322,1325,1328,1331,1334,1337,1341,1344,1347,1350,1353,1356,1359,1362,1365,1368,1371,1374,1377,1380,1383,1386,1389,1392,1395,1398,1402,1405,1408,1412,1415,1418,1421,1424,1427,1430,1433,1436,1439,1442,1445,1448,1451,1454,1457,1460,1463,1466,1469,1472,1476,1479,1483,1486,1489,1492,1496,1499,1502,1505,1508,1511,1514,1517,1520,1523,1526,1529,1532,1535,1538,1541,1544,1548,1551,1554],{"id":20,"text":1058,"url":20,"identifiers":1059},"10.1016\u002FS0968-0004(00)01689-3",{"doi":1058},{"id":20,"text":1061,"url":20,"identifiers":1062},"10.1016\u002F0022-2836(86)90337-2",{"doi":1061},{"id":20,"text":1064,"url":20,"identifiers":1065},"10.1006\u002Fjmbi.2000.3531",{"doi":1064},{"id":20,"text":1067,"url":20,"identifiers":1068},"10.1073\u002Fpnas.121171498",{"doi":1067},{"id":20,"text":1070,"url":20,"identifiers":1071},"10.1007\u002FBF00331045",{"doi":1070},{"id":20,"text":1073,"url":20,"identifiers":1074},"10.3727\u002F000000001783992687",{"doi":1073},{"id":20,"text":1076,"url":20,"identifiers":1077},"10.1073\u002Fpnas.88.22.10148",{"doi":1076},{"id":20,"text":1079,"url":20,"identifiers":1080},"10.1073\u002Fpnas.90.22.10489",{"doi":1079},{"id":20,"text":1082,"url":20,"identifiers":1083},"10.1073\u002Fpnas.92.24.11170",{"doi":1082},{"id":20,"text":1085,"url":20,"identifiers":1086},"10.1002\u002F1521-1878(200010)22:10\u003C873::AID-BIES1>3.3.CO;2-I",{"doi":1085},{"id":20,"text":1088,"url":20,"identifiers":1089},"10.1016\u002F0022-2836(89)90493-2",{"doi":1088},{"id":20,"text":1091,"url":20,"identifiers":1092},"10.1016\u002F0022-2836(84)90383-8",{"doi":1091},{"id":20,"text":1094,"url":20,"identifiers":1095},"10.1006\u002Fjmbi.1997.1297",{"doi":1094},{"id":20,"text":1097,"url":20,"identifiers":1098},"10.1093\u002Fnar\u002F23.14.2685",{"doi":1097},{"id":20,"text":1100,"url":20,"identifiers":1101},"10.1016\u002FS0969-2126(01)00646-3",{"doi":1100},{"id":20,"text":1103,"url":20,"identifiers":1104},"10.1083\u002Fjcb.131.6.1365",{"doi":1103},{"id":20,"text":1106,"url":20,"identifiers":1107},"10.1073\u002Fpnas.95.24.14173",{"doi":1106},{"id":20,"text":1109,"url":20,"identifiers":1110},"10.1083\u002Fjcb.127.2.287",{"doi":1109},{"id":20,"text":1112,"url":20,"identifiers":1113},"10.1016\u002FS0955-0674(99)80041-6",{"doi":1112},{"id":20,"text":1115,"url":20,"identifiers":1116},"10.1007\u002FBF01122502",{"doi":1115},{"id":20,"text":1118,"url":20,"identifiers":1119},"10.1038\u002F247257a0",{"doi":1118},{"id":20,"text":1121,"url":20,"identifiers":1122},"10.1111\u002Fj.1432-1033.1972.tb01790.x",{"doi":1121},{"id":20,"text":1124,"url":20,"identifiers":1125},"10.1016\u002F0022-2836(80)90268-5",{"doi":1124},{"id":20,"text":1127,"url":20,"identifiers":1128},"10.1021\u002Fbi981684e",{"doi":1127},{"id":20,"text":1130,"url":20,"identifiers":1131},"10.1074\u002Fjbc.M006801200",{"doi":1130},{"id":20,"text":1133,"url":20,"identifiers":1134},"10.1016\u002FS0076-6879(99)04004-5",{"doi":1133},{"id":20,"text":1136,"url":20,"identifiers":1137},"10.1021\u002Fbi980716v",{"doi":1136},{"id":20,"text":1139,"url":20,"identifiers":1140},"10.1093\u002Femboj\u002F19.20.5492",{"doi":1139},{"id":20,"text":1142,"url":20,"identifiers":1143},"10.1021\u002Fbi00271a009",{"doi":1142},{"id":20,"text":1145,"url":20,"identifiers":1146},"10.1016\u002F0022-2836(90)90327-I",{"doi":1145},{"id":20,"text":1148,"url":20,"identifiers":1149},"10.1016\u002FS0092-8674(00)00118-5",{"doi":1148},{"id":20,"text":1151,"url":20,"identifiers":1152},"10.1016\u002F0022-2836(90)90081-V",{"doi":1151},{"id":20,"text":1154,"url":20,"identifiers":1155},"10.1038\u002F21436",{"doi":1154},{"id":20,"text":1157,"url":20,"identifiers":1158},"10.1016\u002FS0968-0004(97)01013-X",{"doi":1157},{"id":20,"text":1160,"url":20,"identifiers":1161},"10.1002\u002F(SICI)1521-1878(199905)21:5\u003C367::AID-BIES2>3.0.CO;2-4",{"doi":1160},{"id":20,"text":1163,"url":20,"identifiers":1164},"10.1073\u002Fpnas.97.1.127",{"doi":1163},{"id":20,"text":1166,"url":20,"identifiers":1167},"10.1016\u002FS0968-4328(97)00050-4",{"doi":1166},{"id":20,"text":1169,"url":20,"identifiers":1170},"10.1074\u002Fjbc.271.7.3677",{"doi":1169},{"id":20,"text":1172,"url":20,"identifiers":1173},"10.1021\u002Fbi00499a020",{"doi":1172},{"id":20,"text":1175,"url":20,"identifiers":1176},"10.1093\u002Femboj\u002F19.3.400",{"doi":1175},{"id":20,"text":1178,"url":20,"identifiers":1179},"10.1038\u002F331365a0",{"doi":1178},{"id":20,"text":1181,"url":20,"identifiers":1182},"10.1101\u002Fgad.10.10.1247",{"doi":1181},{"id":20,"text":1184,"url":20,"identifiers":1185},"10.1016\u002F0022-2836(81)90379-X",{"doi":1184},{"id":20,"text":1187,"url":20,"identifiers":1188},"10.1016\u002FS0960-9822(01)00329-3",{"doi":1187},{"id":20,"text":1190,"url":20,"identifiers":1191},"10.1038\u002Fnsb0402-316b",{"doi":1190},{"id":20,"text":1193,"url":20,"identifiers":1194},"10.1074\u002Fjbc.270.43.25359",{"doi":1193},{"id":20,"text":1196,"url":20,"identifiers":1197},"10.1615\u002FCritRevEukarGeneExpr.v6.i2-3.40",{"doi":1196},{"id":20,"text":1199,"url":20,"identifiers":1200},"10.1128\u002FMCB.20.17.6466-6475.2000",{"doi":1199},{"id":20,"text":1202,"url":20,"identifiers":1203},"10.1021\u002Fbi00202a002",{"doi":1202},{"id":20,"text":1205,"url":20,"identifiers":1206},"10.1016\u002FS0960-9822(01)00090-2",{"doi":1205},{"id":20,"text":1208,"url":20,"identifiers":1209},"10.1016\u002F0022-2836(88)90054-X",{"doi":1208},{"id":20,"text":1211,"url":20,"identifiers":1212},"Garcia-Ramirez M, 1992, J. Biol. Chem., 267, 19587, 10.1016\u002FS0021-9258(18)41815-7",{"doi":1213},"10.1016\u002FS0021-9258(18)41815-7",{"id":20,"text":1215,"url":20,"identifiers":1216},"10.1074\u002Fjbc.270.30.17923",{"doi":1215},{"id":20,"text":1218,"url":20,"identifiers":1219},"10.1139\u002Fbcb-79-3-313",{"doi":1218},{"id":20,"text":1221,"url":20,"identifiers":1222},"10.1073\u002Fpnas.151258798",{"doi":1221},{"id":20,"text":1224,"url":20,"identifiers":1225},"10.1016\u002FS0960-9822(00)00714-4",{"doi":1224},{"id":20,"text":1227,"url":20,"identifiers":1228},"10.1139\u002Fbcb-79-3-227",{"doi":1227},{"id":20,"text":1230,"url":20,"identifiers":1231},"10.1074\u002Fjbc.274.9.5626",{"doi":1230},{"id":20,"text":1233,"url":20,"identifiers":1234},"10.1074\u002Fjbc.273.5.3082",{"doi":1233},{"id":20,"text":1236,"url":20,"identifiers":1237},"10.1021\u002Fbi9805846",{"doi":1236},{"id":20,"text":1239,"url":20,"identifiers":1240},"Hansen JC, 1997, Chemtracts Biochem. Mol. Biol., 10, 56",{},{"id":20,"text":1242,"url":20,"identifiers":1243},"10.1021\u002Fbi00449a026",{"doi":1242},{"id":20,"text":1245,"url":20,"identifiers":1246},"Hansen JC, 1993, J. Biol. Chem., 268, 5840, 10.1016\u002FS0021-9258(18)53396-2",{"doi":1247},"10.1016\u002FS0021-9258(18)53396-2",{"id":20,"text":1249,"url":20,"identifiers":1250},"10.1021\u002Fbi982409v",{"doi":1249},{"id":20,"text":1252,"url":20,"identifiers":1253},"Hansen JC, 1991, J. Biol. Chem., 266, 4276, 10.1016\u002FS0021-9258(20)64318-6",{"doi":1254},"10.1016\u002FS0021-9258(20)64318-6",{"id":20,"text":1256,"url":20,"identifiers":1257},"10.1021\u002Fbi00149a032",{"doi":1256},{"id":20,"text":1259,"url":20,"identifiers":1260},"10.1073\u002Fpnas.91.6.2339",{"doi":1259},{"id":20,"text":1262,"url":20,"identifiers":1263},"10.1021\u002Fbi00098a022",{"doi":1262},{"id":20,"text":1265,"url":20,"identifiers":1266},"10.1016\u002FS0959-437X(00)00168-4",{"doi":1265},{"id":20,"text":1268,"url":20,"identifiers":1269},"10.1016\u002F0092-8674(95)90512-X",{"doi":1268},{"id":20,"text":1271,"url":20,"identifiers":1272},"10.1128\u002FMCB.20.2.523-529.2000",{"doi":1271},{"id":20,"text":1274,"url":20,"identifiers":1275},"Hong L, 1993, J. Biol. Chem., 268, 305, 10.1016\u002FS0021-9258(18)54150-8",{"doi":1276},"10.1016\u002FS0021-9258(18)54150-8",{"id":20,"text":1278,"url":20,"identifiers":1279},"10.1074\u002Fjbc.M011153200",{"doi":1278},{"id":20,"text":1281,"url":20,"identifiers":1282},"10.1126\u002Fscience.1063127",{"doi":1281},{"id":20,"text":1284,"url":20,"identifiers":1285},"10.1006\u002Fjmbi.1999.3021",{"doi":1284},{"id":20,"text":1287,"url":20,"identifiers":1288},"10.1074\u002Fjbc.M001142200",{"doi":1287},{"id":20,"text":1290,"url":20,"identifiers":1291},"10.1016\u002FS0092-8674(00)00081-7",{"doi":1290},{"id":20,"text":1293,"url":20,"identifiers":1294},"10.1074\u002Fjbc.M910206199",{"doi":1293},{"id":20,"text":1296,"url":20,"identifiers":1297},"10.1073\u002Fpnas.94.17.8959",{"doi":1296},{"id":20,"text":1299,"url":20,"identifiers":1300},"10.1021\u002Fbi980499y",{"doi":1299},{"id":20,"text":1302,"url":20,"identifiers":1303},"Leuba SH, 1999, Methods Mol. Biol., 119, 143",{},{"id":20,"text":1305,"url":20,"identifiers":1306},"10.1016\u002FS0006-3495(98)77990-1",{"doi":1305},{"id":20,"text":1308,"url":20,"identifiers":1309},"10.1073\u002Fpnas.91.24.11621",{"doi":1308},{"id":20,"text":1311,"url":20,"identifiers":1312},"10.1038\u002F35048603",{"doi":1311},{"id":20,"text":1314,"url":20,"identifiers":1315},"10.1093\u002Fnar\u002F4.6.2039",{"doi":1314},{"id":20,"text":1317,"url":20,"identifiers":1318},"10.1093\u002Femboj\u002F16.22.6772",{"doi":1317},{"id":20,"text":1320,"url":20,"identifiers":1321},"10.1021\u002Fbi982109d",{"doi":1320},{"id":20,"text":1323,"url":20,"identifiers":1324},"10.1038\u002F38444",{"doi":1323},{"id":20,"text":1326,"url":20,"identifiers":1327},"10.1016\u002FS0076-6879(99)04003-3",{"doi":1326},{"id":20,"text":1329,"url":20,"identifiers":1330},"10.1016\u002FS0959-440X(98)80007-9",{"doi":1329},{"id":20,"text":1332,"url":20,"identifiers":1333},"10.1016\u002FS0959-437X(98)80134-2",{"doi":1332},{"id":20,"text":1335,"url":20,"identifiers":1336},"10.1021\u002Fbi00172a003",{"doi":1335},{"id":20,"text":1338,"url":20,"identifiers":1339},"Mann RK, 1992, EMBO J., 11, 3297, 10.1002\u002Fj.1460-2075.1992.tb05408.x",{"doi":1340},"10.1002\u002Fj.1460-2075.1992.tb05408.x",{"id":20,"text":1342,"url":20,"identifiers":1343},"10.1093\u002Fnar\u002F11.12.4065",{"doi":1342},{"id":20,"text":1345,"url":20,"identifiers":1346},"10.1074\u002Fjbc.273.11.6582",{"doi":1345},{"id":20,"text":1348,"url":20,"identifiers":1349},"10.1038\u002F35048610",{"doi":1348},{"id":20,"text":1351,"url":20,"identifiers":1352},"10.1006\u002Fbbrc.1996.5903",{"doi":1351},{"id":20,"text":1354,"url":20,"identifiers":1355},"10.1101\u002FSQB.1993.058.01.032",{"doi":1354},{"id":20,"text":1357,"url":20,"identifiers":1358},"10.1083\u002Fjcb.200011069",{"doi":1357},{"id":20,"text":1360,"url":20,"identifiers":1361},"10.1128\u002FMCB.18.11.6293",{"doi":1360},{"id":20,"text":1363,"url":20,"identifiers":1364},"10.1016\u002F0092-8674(89)90399-1",{"doi":1363},{"id":20,"text":1366,"url":20,"identifiers":1367},"10.1073\u002Fpnas.91.22.10275",{"doi":1366},{"id":20,"text":1369,"url":20,"identifiers":1370},"10.1006\u002Fjmbi.2000.3644",{"doi":1369},{"id":20,"text":1372,"url":20,"identifiers":1373},"10.1006\u002Fjmbi.1995.0606",{"doi":1372},{"id":20,"text":1375,"url":20,"identifiers":1376},"10.1006\u002Fjmbi.1996.0288",{"doi":1375},{"id":20,"text":1378,"url":20,"identifiers":1379},"10.1093\u002Femboj\u002F18.20.5622",{"doi":1378},{"id":20,"text":1381,"url":20,"identifiers":1382},"10.1093\u002Fnar\u002F19.4.717",{"doi":1381},{"id":20,"text":1384,"url":20,"identifiers":1385},"10.1021\u002Fbi00078a002",{"doi":1384},{"id":20,"text":1387,"url":20,"identifiers":1388},"10.1615\u002FCritRevEukarGeneExpr.v7.i3.20",{"doi":1387},{"id":20,"text":1390,"url":20,"identifiers":1391},"10.1146\u002Fannurev.biophys.26.1.83",{"doi":1390},{"id":20,"text":1393,"url":20,"identifiers":1394},"10.1038\u002F362219a0",{"doi":1393},{"id":20,"text":1396,"url":20,"identifiers":1397},"10.1016\u002FS0955-0674(00)00208-8",{"doi":1396},{"id":20,"text":1399,"url":20,"identifiers":1400},"Ridsdale JA, 1990, J. Biol. Chem., 265, 5150, 10.1016\u002FS0021-9258(19)34098-0",{"doi":1401},"10.1016\u002FS0021-9258(19)34098-0",{"id":20,"text":1403,"url":20,"identifiers":1404},"10.1146\u002Fannurev.biochem.70.1.81",{"doi":1403},{"id":20,"text":1406,"url":20,"identifiers":1407},"10.1021\u002Fbi9525684",{"doi":1406},{"id":20,"text":1409,"url":20,"identifiers":1410},"Schwarz PM, 1994, J. Biol. Chem., 269, 16284, 10.1016\u002FS0021-9258(17)34005-X",{"doi":1411},"10.1016\u002FS0021-9258(17)34005-X",{"id":20,"text":1413,"url":20,"identifiers":1414},"10.1021\u002Fbi00355a004",{"doi":1413},{"id":20,"text":1416,"url":20,"identifiers":1417},"10.1021\u002Fbi00618a030",{"doi":1416},{"id":20,"text":1419,"url":20,"identifiers":1420},"10.1016\u002F0092-8674(85)90276-4",{"doi":1419},{"id":20,"text":1422,"url":20,"identifiers":1423},"10.1016\u002F0022-2836(79)90421-2",{"doi":1422},{"id":20,"text":1425,"url":20,"identifiers":1426},"10.1002\u002F(SICI)1521-1878(199801)20:1\u003C30::AID-BIES6>3.0.CO;2-W",{"doi":1425},{"id":20,"text":1428,"url":20,"identifiers":1429},"10.1038\u002F47412",{"doi":1428},{"id":20,"text":1431,"url":20,"identifiers":1432},"10.1016\u002F0014-5793(92)80416-E",{"doi":1431},{"id":20,"text":1434,"url":20,"identifiers":1435},"10.1038\u002F81971",{"doi":1434},{"id":20,"text":1437,"url":20,"identifiers":1438},"10.1016\u002F0092-8674(77)90188-X",{"doi":1437},{"id":20,"text":1440,"url":20,"identifiers":1441},"10.1083\u002Fjcb.83.2.403",{"doi":1440},{"id":20,"text":1443,"url":20,"identifiers":1444},"10.1016\u002FS0022-2836(83)80102-8",{"doi":1443},{"id":20,"text":1446,"url":20,"identifiers":1447},"10.1016\u002FS0955-0674(99)80042-8",{"doi":1446},{"id":20,"text":1449,"url":20,"identifiers":1450},"10.1016\u002FS0968-0004(98)01339-5",{"doi":1449},{"id":20,"text":1452,"url":20,"identifiers":1453},"10.1073\u002Fpnas.95.10.5468",{"doi":1452},{"id":20,"text":1455,"url":20,"identifiers":1456},"10.1073\u002Fpnas.95.21.12169",{"doi":1455},{"id":20,"text":1458,"url":20,"identifiers":1459},"10.1021\u002Fbi970801n",{"doi":1458},{"id":20,"text":1461,"url":20,"identifiers":1462},"10.1128\u002FMCB.18.8.4629",{"doi":1461},{"id":20,"text":1464,"url":20,"identifiers":1465},"10.1073\u002Fpnas.91.15.6845",{"doi":1464},{"id":20,"text":1467,"url":20,"identifiers":1468},"van Holde KE, 1988, Chromatin.",{},{"id":20,"text":1470,"url":20,"identifiers":1471},"10.1002\u002Fbip.1978.360170602",{"doi":1470},{"id":20,"text":1473,"url":20,"identifiers":1474},"van Holde KE, Yager TD. 1985.Nucleosome motion: evidence and models.InStructure and Function of the Genetic Apparatus, ed. C Niccolini, POP Ts'o, pp. 35–53. New York: Plenum",{"doi":1475},"10.1007\u002F978-1-4684-5024-8_4",{"id":20,"text":1477,"url":20,"identifiers":1478},"10.1074\u002Fjbc.270.15.8373",{"doi":1477},{"id":20,"text":1480,"url":20,"identifiers":1481},"Varga-Weisz PD, 1995, EMBO J., 14, 2209, 10.1002\u002Fj.1460-2075.1995.tb07215.x",{"doi":1482},"10.1002\u002Fj.1460-2075.1995.tb07215.x",{"id":20,"text":1484,"url":20,"identifiers":1485},"10.1021\u002Fbi00318a037",{"doi":1484},{"id":20,"text":1487,"url":20,"identifiers":1488},"10.1074\u002Fjbc.M100501200",{"doi":1487},{"id":20,"text":1490,"url":20,"identifiers":1491},"10.1074\u002Fjbc.M004998200",{"doi":1490},{"id":20,"text":1493,"url":20,"identifiers":1494},"Whitlock JP, 1977, J. Biol. Chem., 252, 6516, 10.1016\u002FS0021-9258(17)39988-X",{"doi":1495},"10.1016\u002FS0021-9258(17)39988-X",{"id":20,"text":1497,"url":20,"identifiers":1498},"10.1016\u002F0022-2836(86)90012-4",{"doi":1497},{"id":20,"text":1500,"url":20,"identifiers":1501},"10.1146\u002Fannurev.bb.18.060189.002053",{"doi":1500},{"id":20,"text":1503,"url":20,"identifiers":1504},"10.1016\u002FS0960-9822(07)00500-3",{"doi":1503},{"id":20,"text":1506,"url":20,"identifiers":1507},"10.1146\u002Fannurev.biophys.27.1.285",{"doi":1506},{"id":20,"text":1509,"url":20,"identifiers":1510},"Widom J, 1999, Methods Mol. Biol., 119, 61",{},{"id":20,"text":1512,"url":20,"identifiers":1513},"10.1016\u002FS1357-2725(97)00026-5",{"doi":1512},{"id":20,"text":1515,"url":20,"identifiers":1516},"Wolffe AP, 1998, Chromatin: Structure and Function.",{},{"id":20,"text":1518,"url":20,"identifiers":1519},"10.1006\u002Fjsbi.2000.4217",{"doi":1518},{"id":20,"text":1521,"url":20,"identifiers":1522},"Wolffe AP, 2001, Cell, 104, 631",{},{"id":20,"text":1524,"url":20,"identifiers":1525},"10.1093\u002Fnar\u002F27.3.711",{"doi":1524},{"id":20,"text":1527,"url":20,"identifiers":1528},"10.1002\u002Fbies.950190311",{"doi":1527},{"id":20,"text":1530,"url":20,"identifiers":1531},"10.1016\u002FS0959-437X(00)00169-6",{"doi":1530},{"id":20,"text":1533,"url":20,"identifiers":1534},"10.1016\u002FS0962-8924(00)89038-8",{"doi":1533},{"id":20,"text":1536,"url":20,"identifiers":1537},"10.1146\u002Fannurev.biochem.67.1.545",{"doi":1536},{"id":20,"text":1539,"url":20,"identifiers":1540},"10.1016\u002FS0968-0004(00)01718-7",{"doi":1539},{"id":20,"text":1542,"url":20,"identifiers":1543},"10.1021\u002Fbi00431a045",{"doi":1542},{"id":20,"text":1545,"url":20,"identifiers":1546},"Yager TD, 1984, J. Biol. Chem., 259, 4212, 10.1016\u002FS0021-9258(17)43032-8",{"doi":1547},"10.1016\u002FS0021-9258(17)43032-8",{"id":20,"text":1549,"url":20,"identifiers":1550},"10.1021\u002Fbi991034q",{"doi":1549},{"id":20,"text":1552,"url":20,"identifiers":1553},"10.1016\u002FS0006-3495(98)77963-9",{"doi":1552},{"id":20,"text":1555,"url":20,"identifiers":1556},"10.1615\u002FCritRevEukarGeneExpr.v9.i3-4.90",{"doi":1555},{"id":1558,"createTime":1559,"updateTime":1559,"relativeEntities":1560,"slug":1561,"properties":1562,"entityType":48,"verifyStatus":49,"verifyTime":1559,"verifyNote":50,"syncStatus":19,"languages":1576,"translateLanguages":20,"viewCount":21,"primaryUrl":1577,"fullTextUrl":20,"authors":1578,"publicationType":95,"publisherRelationship":1620,"citationCount":1636,"citationInfo":1637,"publishDate":1649,"publishYear":1650,"citationAnalyzeStatus":19,"lastCitationAnalyze":20,"indexDatabases":20,"openAccess":20,"references":1651,"isForceReanalyzing":360},"2210cb6c-f9dc-4f24-aec9-fdb57e2ec3f7","2024-09-04T20:47:29.602+00:00",[],"SINGLE-PARTICLE-TRACKING-Applications-to-Membrane-Dynamics",{"mag":1563,"keywords":1565,"openalex":1566,"abstract":1568,"title":1570,"pm":1572,"doi":1574},{"VOID":1564},"2147688960",{},{"VOID":1567},"W2147688960",{"EN":1569},"\u003Cjats:p>▪ Abstract  Measurements of trajectories of individual proteins or lipids in the plasma membrane of cells show a variety of types of motion. Brownian motion is observed, but many of the particles undergo non-Brownian motion, including directed motion, confined motion, and anomalous diffusion. The variety of motion leads to significant effects on the kinetics of reactions among membrane-bound species and requires a revision of existing views of membrane structure and dynamics.\u003C\u002Fjats:p>",{"EN":1571},"SINGLE-PARTICLE TRACKING:Applications to Membrane Dynamics",{"VOID":1573},"9241424",{"VOID":1575},"10.1146\u002Fannurev.biophys.26.1.373",[52],"https:\u002F\u002Fwww.annualreviews.org\u002Fdoi\u002F10.1146\u002Fannurev.biophys.26.1.373",[1579,1598],{"id":1580,"sortIndex":21,"researcher":20,"roles":1581,"affiliations":1582,"properties":1593},"d878020c-8738-4984-ae46-dcafd7ad24e7",[],[1583],{"id":1584,"sortIndex":21,"affiliation":1585,"properties":20},"cbb30e9b-0334-4d94-a366-6a2a9dce1218",{"id":1586,"createTime":1587,"updateTime":1587,"relativeEntities":1588,"slug":1589,"properties":1590,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"18f27b56-eff8-429a-871c-fecaf1d91536","2024-09-04T20:47:29.610+00:00",[],"Institute-of-Theoretical-Dynamics-University-of-California-Davis-California-95616-",{"title":1591},{"EN":1592},"Institute of Theoretical Dynamics, University of California, Davis, California 95616;",{"openalex":1594,"title":1596},{"VOID":1595},"A5076482416",{"EN":1597},"Michael J. Saxton",{"id":1599,"sortIndex":57,"researcher":20,"roles":1600,"affiliations":1601,"properties":1613},"3d4a3bf3-0379-4029-a93f-8e4267e32aff",[],[1602],{"id":1603,"sortIndex":21,"affiliation":1604,"properties":20},"f6d56d12-9fb5-400b-bbef-3d54d6d630ec",{"id":1605,"createTime":1606,"updateTime":1607,"relativeEntities":1608,"slug":1609,"properties":1610,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"225265ae-a9e0-40e3-9ff3-1417b96af090","2023-12-25T08:12:21.638+00:00","2024-09-04T20:47:29.622+00:00",[],"Department-of-Cell-Biology-and-Anatomy-University-of-North-Carolina-at-Chapel-Hill-Chapel-Hill-North-Carolina-27599",{"title":1611},{"VI":1612},"Department of Cell Biology and Anatomy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599",{"openalex":1614,"orcid":1616,"title":1618},{"VOID":1615},"A5103240397",{"VOID":1617},"https:\u002F\u002Forcid.org\u002F0000-0001-9517-9098",{"EN":1619},"Ken Jacobson",{"url":20,"publisher":1621,"properties":1630},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1622,"slug":10,"properties":1623,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":1627,"manageAffiliations":1628,"indexDatabases":1629,"url":20,"thumbnailPath":20,"statistic":20,"gsStatistic":20,"type":20,"analyzePriority":20},[],{"issn":1624,"eissn":1625,"title":1626},{"VOID":13},{"VOID":15},{"EN":17},[],[],[],{"volume":1631,"pages":1633,"issue":1635},{"VOID":1632},"26",{"VOID":1634},"373-399",{"VOID":112},1741,{"total":1636,"publishYear":20,"statisticByYear":1638},{"2012":1639,"2013":1640,"2014":1641,"2015":1642,"2016":1643,"2017":1644,"2018":1645,"2019":1646,"2020":1647,"2021":437,"2022":511,"2023":1648,"2024":520},120,107,111,100,85,81,88,74,78,52,"1997-06-01",1997,[1652,1655,1659,1662,1665,1668,1671,1675,1678,1681,1684,1687,1690,1693,1695,1698,1701,1704,1707,1710,1713,1716,1719,1722,1725,1728,1731,1734,1737,1740,1743,1747,1751,1754,1757,1760,1763,1766,1769,1772,1775,1778,1781,1784,1787,1790,1793,1796,1799,1802,1805,1808,1811,1814,1817,1820,1823,1826,1829,1832,1835,1838,1841,1844,1847,1850,1853,1856,1859,1862,1865,1868,1871,1874,1877,1880,1883,1886,1889,1892,1895,1898,1901,1904,1907,1910,1912,1915,1918,1921,1924,1927,1930,1933,1936,1939,1942,1945,1948,1951,1954,1957,1960,1963,1966,1969,1972,1975,1979],{"id":20,"text":1653,"url":20,"identifiers":1654},"10.1016\u002FS1383-8121(06)80023-0",{"doi":1653},{"id":20,"text":1656,"url":20,"identifiers":1657},"Anderson CM, 1992, J. Cell Sci., 101, 415, 10.1242\u002Fjcs.101.2.415",{"doi":1658},"10.1242\u002Fjcs.101.2.415",{"id":20,"text":1660,"url":20,"identifiers":1661},"10.1007\u002F978-94-009-4734-4_20",{"doi":1660},{"id":20,"text":1663,"url":20,"identifiers":1664},"10.1083\u002Fjcb.90.3.595",{"doi":1663},{"id":20,"text":1666,"url":20,"identifiers":1667},"10.1083\u002Fjcb.95.3.846",{"doi":1666},{"id":20,"text":1669,"url":20,"identifiers":1670},"Beaurepaire E, 1995, Biophys. J., 68, A288",{},{"id":20,"text":1672,"url":20,"identifiers":1673},"Bergelson LD, 1995, Mol. Membr. Biol., 12, 1, 10.3109\u002F09687689509038486",{"doi":1674},"10.3109\u002F09687689509038486",{"id":20,"text":1676,"url":20,"identifiers":1677},"Block SM. 1990. Optical tweezers: a new tool for biophysics. See Ref.38, pp. 375–402",{},{"id":20,"text":1679,"url":20,"identifiers":1680},"10.1016\u002FS0006-3495(94)80511-9",{"doi":1679},{"id":20,"text":1682,"url":20,"identifiers":1683},"10.1016\u002FS0006-3495(95)79909-X",{"doi":1682},{"id":20,"text":1685,"url":20,"identifiers":1686},"10.1016\u002F0370-1573(90)90099-N",{"doi":1685},{"id":20,"text":1688,"url":20,"identifiers":1689},"10.1016\u002FS0960-9822(02)00467-0",{"doi":1688},{"id":20,"text":1691,"url":20,"identifiers":1692},"10.1016\u002FS0092-8674(00)81246-5",{"doi":1691},{"id":20,"text":568,"url":20,"identifiers":1694},{"doi":568},{"id":20,"text":1696,"url":20,"identifiers":1697},"10.1017\u002FS0022112094003289",{"doi":1696},{"id":20,"text":1699,"url":20,"identifiers":1700},"10.1017\u002FS002211209200288X",{"doi":1699},{"id":20,"text":1702,"url":20,"identifiers":1703},"10.1016\u002FS0006-3495(95)80359-0",{"doi":1702},{"id":20,"text":1705,"url":20,"identifiers":1706},"10.1016\u002FS0006-3495(95)80360-7",{"doi":1705},{"id":20,"text":1708,"url":20,"identifiers":1709},"10.1016\u002FS0006-3495(95)80365-6",{"doi":1708},{"id":20,"text":1711,"url":20,"identifiers":1712},"10.1042\u002Fbst0220781",{"doi":1711},{"id":20,"text":1714,"url":20,"identifiers":1715},"10.1007\u002F978-1-4757-5348-6_32",{"doi":1714},{"id":20,"text":1717,"url":20,"identifiers":1718},"10.1006\u002Fjcis.1996.0217",{"doi":1717},{"id":20,"text":1720,"url":20,"identifiers":1721},"10.1016\u002F0092-8674(95)90182-5",{"doi":1720},{"id":20,"text":1723,"url":20,"identifiers":1724},"De Brabander M, Geerts H, Nuydens R, Nuydens R, Cornelissen F. 1993. Nanovid microscopy: imaging and quantification of colloidal gold labels in living cells. See Ref.92, pp. 141–55",{},{"id":20,"text":1726,"url":20,"identifiers":1727},"De Brabander M, 1985, Cytobios, 43, 273",{},{"id":20,"text":1729,"url":20,"identifiers":1730},"10.1083\u002Fjcb.112.1.111",{"doi":1729},{"id":20,"text":1732,"url":20,"identifiers":1733},"10.1017\u002FS0022112095001674",{"doi":1732},{"id":20,"text":1735,"url":20,"identifiers":1736},"10.1016\u002FS0070-2161(08)60169-0",{"doi":1735},{"id":20,"text":1738,"url":20,"identifiers":1739},"Edidin M. 1992.Translational diffusion of membrane proteins.InThe Structure of Biological Membranes, ed. P Yeagle, pp. 539–72. Boca Raton: CRC",{},{"id":20,"text":1741,"url":20,"identifiers":1742},"10.1242\u002Fjcs.1993.Supplement_17.24",{"doi":1741},{"id":20,"text":1744,"url":20,"identifiers":1745},"Edidin M. 1994.Lateral mobility of membrane proteins—a journey from heterokaryons to laser tweezers.InThe Legacy of Cell Fusion, ed. S Gordon, pp. 101–14. Oxford: Oxford Univ. Press",{"doi":1746},"10.1093\u002Foso\u002F9780198547723.003.0007",{"id":20,"text":1748,"url":20,"identifiers":1749},"Edidin M. 1994.Fluorescence photobleaching and recovery, FPR, in the analysis of membrane structure and dynamics.InMobility and Proximity in Biological Membranes, ed. S Damjanovich, J Szöll H osi, L Trón, M Edidin, pp. 109–35. Boca Raton: CRC",{"doi":1750},"10.1201\u002F9781351074674-3",{"id":20,"text":1752,"url":20,"identifiers":1753},"10.1016\u002FS0070-2161(08)60381-0",{"doi":1752},{"id":20,"text":1755,"url":20,"identifiers":1756},"10.1126\u002Fscience.1835798",{"doi":1755},{"id":20,"text":1758,"url":20,"identifiers":1759},"10.1073\u002Fpnas.91.8.3378",{"doi":1758},{"id":20,"text":1761,"url":20,"identifiers":1762},"10.1007\u002F978-3-662-03008-0_9",{"doi":1761},{"id":20,"text":1764,"url":20,"identifiers":1765},"10.1016\u002FS0006-3495(96)79846-6",{"doi":1764},{"id":20,"text":1767,"url":20,"identifiers":1768},"10.1007\u002FBF00234654",{"doi":1767},{"id":20,"text":1770,"url":20,"identifiers":1771},"Foskett JK, Grinstein S, eds. 1990.Noninvasive Techniques in Cell Biology. New York: Wiley-Liss. 423 pp.",{},{"id":20,"text":1773,"url":20,"identifiers":1774},"Fredrickson GH, 1995, J. Phys. II (Paris), 5, 369",{},{"id":20,"text":1776,"url":20,"identifiers":1777},"10.1016\u002FS0166-2236(96)80025-7",{"doi":1776},{"id":20,"text":1779,"url":20,"identifiers":1780},"10.1038\u002F331450a0",{"doi":1779},{"id":20,"text":1782,"url":20,"identifiers":1783},"Ghosh RN. 1991.Mobility and clustering of individual low-density lipoprotein receptor molecules on the surface of human skin fibroblasts. PhD thesis. Cornell Univ., Ithaca. 260 pp.",{},{"id":20,"text":1785,"url":20,"identifiers":1786},"10.1016\u002FS0006-3495(94)80939-7",{"doi":1785},{"id":20,"text":1788,"url":20,"identifiers":1789},"10.1073\u002Fpnas.83.17.6258",{"doi":1788},{"id":20,"text":1791,"url":20,"identifiers":1792},"10.1016\u002FS0006-3495(86)83718-3",{"doi":1791},{"id":20,"text":1794,"url":20,"identifiers":1795},"10.1007\u002FBF00236836",{"doi":1794},{"id":20,"text":1797,"url":20,"identifiers":1798},"Deleted in proof",{},{"id":20,"text":1800,"url":20,"identifiers":1801},"10.1007\u002F978-1-4757-6925-8",{"doi":1800},{"id":20,"text":1803,"url":20,"identifiers":1804},"10.1016\u002FS0091-679X(08)60976-0",{"doi":1803},{"id":20,"text":1806,"url":20,"identifiers":1807},"10.1073\u002Fpnas.84.5.1290",{"doi":1806},{"id":20,"text":1809,"url":20,"identifiers":1810},"10.1083\u002Fjcb.99.5.1624",{"doi":1809},{"id":20,"text":1812,"url":20,"identifiers":1813},"10.1016\u002FS0006-3495(94)80965-8",{"doi":1812},{"id":20,"text":1815,"url":20,"identifiers":1816},"10.1016\u002FS0006-3495(94)80801-X",{"doi":1815},{"id":20,"text":1818,"url":20,"identifiers":1819},"10.1038\u002F340315a0",{"doi":1818},{"id":20,"text":1821,"url":20,"identifiers":1822},"10.1083\u002Fjcb.111.4.1617",{"doi":1821},{"id":20,"text":1824,"url":20,"identifiers":1825},"10.1016\u002FS0955-0674(96)80036-6",{"doi":1824},{"id":20,"text":1827,"url":20,"identifiers":1828},"10.1016\u002FS0006-3495(93)81253-0",{"doi":1827},{"id":20,"text":1830,"url":20,"identifiers":1831},"10.1073\u002Fpnas.88.14.6274",{"doi":1830},{"id":20,"text":1833,"url":20,"identifiers":1834},"10.1083\u002Fjcb.123.6.1899",{"doi":1833},{"id":20,"text":1836,"url":20,"identifiers":1837},"10.1083\u002Fjcb.120.1.25",{"doi":1836},{"id":20,"text":1839,"url":20,"identifiers":1840},"10.1126\u002Fscience.2315695",{"doi":1839},{"id":20,"text":1842,"url":20,"identifiers":1843},"10.1103\u002FPhysRevE.52.5810",{"doi":1842},{"id":20,"text":1845,"url":20,"identifiers":1846},"10.1146\u002Fannurev.bb.22.060193.001045",{"doi":1845},{"id":20,"text":1848,"url":20,"identifiers":1849},"10.1016\u002FS0006-3495(92)81602-8",{"doi":1848},{"id":20,"text":1851,"url":20,"identifiers":1852},"10.1126\u002Fscience.7660120",{"doi":1851},{"id":20,"text":1854,"url":20,"identifiers":1855},"10.1016\u002FS0006-3495(91)82125-7",{"doi":1854},{"id":20,"text":1857,"url":20,"identifiers":1858},"10.1126\u002Fscience.237.4813.384",{"doi":1857},{"id":20,"text":1860,"url":20,"identifiers":1861},"10.1083\u002Fjcb.125.6.1251",{"doi":1860},{"id":20,"text":1863,"url":20,"identifiers":1864},"10.1083\u002Fjcb.129.6.1559",{"doi":1863},{"id":20,"text":1866,"url":20,"identifiers":1867},"10.1016\u002FS0006-3495(90)82470-X",{"doi":1866},{"id":20,"text":1869,"url":20,"identifiers":1870},"10.1016\u002FS0006-3495(93)81471-1",{"doi":1869},{"id":20,"text":1872,"url":20,"identifiers":1873},"10.1016\u002FS0006-3495(93)81548-0",{"doi":1872},{"id":20,"text":1875,"url":20,"identifiers":1876},"10.1016\u002FS0006-3495(94)80789-1",{"doi":1875},{"id":20,"text":1878,"url":20,"identifiers":1879},"10.1016\u002FS0006-3495(94)80694-0",{"doi":1878},{"id":20,"text":1881,"url":20,"identifiers":1882},"10.1016\u002FS0006-3495(95)79911-8",{"doi":1881},{"id":20,"text":1884,"url":20,"identifiers":1885},"10.1016\u002FS0006-3495(96)79682-0",{"doi":1884},{"id":20,"text":1887,"url":20,"identifiers":1888},"10.1063\u002F1.881289",{"doi":1887},{"id":20,"text":1890,"url":20,"identifiers":1891},"10.1016\u002FS0006-3495(94)80502-8",{"doi":1890},{"id":20,"text":1893,"url":20,"identifiers":1894},"10.1083\u002Fjcb.123.4.977",{"doi":1893},{"id":20,"text":1896,"url":20,"identifiers":1897},"10.1021\u002Fj100049a030",{"doi":1896},{"id":20,"text":1899,"url":20,"identifiers":1900},"10.1073\u002Fpnas.93.7.2926",{"doi":1899},{"id":20,"text":1902,"url":20,"identifiers":1903},"Schmidt Th, 1996, Biophys. J., 70, A426",{},{"id":20,"text":1905,"url":20,"identifiers":1906},"10.1002\u002Fcm.970100109",{"doi":1905},{"id":20,"text":1908,"url":20,"identifiers":1909},"10.1126\u002Fscience.7660128",{"doi":1908},{"id":20,"text":893,"url":20,"identifiers":1911},{"doi":893},{"id":20,"text":1913,"url":20,"identifiers":1914},"Sheets ED, 1996, Biophys. J., 70, A335",{},{"id":20,"text":1916,"url":20,"identifiers":1917},"10.1016\u002F0955-0674(95)80113-8",{"doi":1916},{"id":20,"text":1919,"url":20,"identifiers":1920},"Sheetz MP, 1983, Semin. Hematol., 20, 175",{},{"id":20,"text":1922,"url":20,"identifiers":1923},"10.1146\u002Fannurev.bb.22.060193.002221",{"doi":1922},{"id":20,"text":1925,"url":20,"identifiers":1926},"10.1016\u002F0092-8674(90)90804-N",{"doi":1925},{"id":20,"text":1928,"url":20,"identifiers":1929},"10.1016\u002FB978-0-08-057139-3.50014-4",{"doi":1928},{"id":20,"text":1931,"url":20,"identifiers":1932},"10.1016\u002FS0091-679X(08)60166-1",{"doi":1931},{"id":20,"text":1934,"url":20,"identifiers":1935},"10.1038\u002F340284a0",{"doi":1934},{"id":20,"text":1937,"url":20,"identifiers":1938},"10.1016\u002F0005-2736(89)90325-8",{"doi":1937},{"id":20,"text":1940,"url":20,"identifiers":1941},"Shotton D. 1993.Electronic Light Microscopy. New York: Wiley-Liss. 355 pp.",{},{"id":20,"text":1943,"url":20,"identifiers":1944},"Simson R. 1994.Different modes of lateral mobility for neural cell adhesion molecules as observed by nanovid microscopy and single particle tracking. Diplomarbeit [thesis]. Technische Univ. München. 78 pp.",{},{"id":20,"text":1946,"url":20,"identifiers":1947},"10.1016\u002FS0006-3495(95)79972-6",{"doi":1946},{"id":20,"text":1949,"url":20,"identifiers":1950},"Slattery JP. 1995.Lateral mobility of FcεRI on rat basophilic leukemia cells as measured by single particle tracking using a novel bright fluorescent probe. PhD thesis. Cornell Univ., Ithaca. 153 pp.",{},{"id":20,"text":1952,"url":20,"identifiers":1953},"10.1146\u002Fannurev.bb.23.060194.001335",{"doi":1952},{"id":20,"text":1955,"url":20,"identifiers":1956},"10.1364\u002FOL.19.000930",{"doi":1955},{"id":20,"text":1958,"url":20,"identifiers":1959},"Thomas J, Webb WW. 1990. Fluorescence photobleaching recovery: a probe of membrane dynamics. See Ref.38, pp. 129–52",{},{"id":20,"text":1961,"url":20,"identifiers":1962},"10.3109\u002F09687689509038512",{"doi":1961},{"id":20,"text":1964,"url":20,"identifiers":1965},"10.1111\u002Fj.1365-2818.1990.tb03054.x",{"doi":1964},{"id":20,"text":1967,"url":20,"identifiers":1968},"10.1083\u002Fjcb.109.6.3325",{"doi":1967},{"id":20,"text":1970,"url":20,"identifiers":1971},"10.1083\u002Fjcb.127.4.963",{"doi":1970},{"id":20,"text":1973,"url":20,"identifiers":1974},"Webb WW, 1981, Biochem. Soc. Symp., 46, 191",{},{"id":20,"text":1976,"url":20,"identifiers":1977},"Wilson KM, 1996, J. Cell Sci., 109, 2101, 10.1242\u002Fjcs.109.8.2101",{"doi":1978},"10.1242\u002Fjcs.109.8.2101",{"id":20,"text":1980,"url":20,"identifiers":1981},"10.1002\u002Fbies.950150903",{"doi":1980},{"id":1983,"createTime":1984,"updateTime":1984,"relativeEntities":1985,"slug":1986,"properties":1987,"entityType":48,"verifyStatus":49,"verifyTime":1984,"verifyNote":50,"syncStatus":19,"languages":2001,"translateLanguages":20,"viewCount":21,"primaryUrl":2002,"fullTextUrl":20,"authors":2003,"publicationType":95,"publisherRelationship":2043,"citationCount":2058,"citationInfo":2059,"publishDate":2068,"publishYear":2069,"citationAnalyzeStatus":19,"lastCitationAnalyze":20,"indexDatabases":20,"openAccess":20,"references":2070,"isForceReanalyzing":360},"0ec0a2ed-b887-4853-961d-ad3049e6b2da","2024-09-28T20:46:36.443+00:00",[],"EVOLUTIONARY-RELATIONSHIPS-AND-STRUCTURAL-MECHANISMS-OF-AAA-PROTEINS",{"mag":1988,"keywords":1990,"openalex":1991,"abstract":1993,"title":1995,"pm":1997,"doi":1999},{"VOID":1989},"2121431496",{},{"VOID":1992},"W2121431496",{"EN":1994},"\u003Cjats:p>Complex cellular events commonly depend on the activity of molecular “machines” that efficiently couple enzymatic and regulatory functions within a multiprotein assembly. An essential and expanding subset of these assemblies comprises proteins of the ATPases associated with diverse cellular activities (AAA+) family. The defining feature of AAA+ proteins is a structurally conserved ATP-binding module that oligomerizes into active arrays. ATP binding and hydrolysis events at the interface of neighboring subunits drive conformational changes within the AAA+ assembly that direct translocation or remodeling of target substrates. In this review, we describe the critical features of the AAA+ domain, summarize our current knowledge of how this versatile element is incorporated into larger assemblies, and discuss specific adaptations of the AAA+ fold that allow complex molecular manipulations to be carried out for a highly diverse set of macromolecular targets.\u003C\u002Fjats:p>",{"EN":1996},"EVOLUTIONARY RELATIONSHIPS AND STRUCTURAL MECHANISMS OF AAA+ PROTEINS",{"VOID":1998},"16689629",{"VOID":2000},"10.1146\u002Fannurev.biophys.35.040405.101933",[52],"https:\u002F\u002Fwww.annualreviews.org\u002Fdoi\u002F10.1146\u002Fannurev.biophys.35.040405.101933",[2004,2026],{"id":2005,"sortIndex":21,"researcher":20,"roles":2006,"affiliations":2007,"properties":2019},"312d6473-0fa6-433e-8ed5-b2c47ef15b51",[],[2008],{"id":2009,"sortIndex":21,"affiliation":2010,"properties":20},"47861171-50d5-4577-8eff-037c6b6d6443",{"id":2011,"createTime":2012,"updateTime":2013,"relativeEntities":2014,"slug":2015,"properties":2016,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"bd619455-befc-4e63-8826-97a08ca0a0ff","2024-02-06T18:34:50.351+00:00","2024-12-20T21:32:14.504+00:00",[],"Department-of-Molecular-and-Cell-Biology-University-of-California-Berkeley-California-94720",{"title":2017},{"VI":2018},"Department of Molecular and Cell Biology, University of California, Berkeley, California 94720",{"openalex":2020,"orcid":2022,"title":2024},{"VOID":2021},"A5039986206",{"VOID":2023},"https:\u002F\u002Forcid.org\u002F0000-0002-0266-8835",{"EN":2025},"Jan P. Erzberger",{"id":2027,"sortIndex":57,"researcher":20,"roles":2028,"affiliations":2029,"properties":2036},"7d49ee79-8558-4a21-a614-6ce04763eb4a",[],[2030],{"id":2031,"sortIndex":21,"affiliation":2032,"properties":20},"97edeb0d-4063-4456-be48-d39295019c15",{"id":2011,"createTime":2012,"updateTime":2013,"relativeEntities":2033,"slug":2015,"properties":2034,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},[],{"title":2035},{"VI":2018},{"openalex":2037,"orcid":2039,"title":2041},{"VOID":2038},"A5039868655",{"VOID":2040},"https:\u002F\u002Forcid.org\u002F0000-0003-0666-1240",{"EN":2042},"James M. Berger",{"url":20,"publisher":2044,"properties":2053},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":2045,"slug":10,"properties":2046,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":2050,"manageAffiliations":2051,"indexDatabases":2052,"url":20,"thumbnailPath":20,"statistic":20,"gsStatistic":20,"type":20,"analyzePriority":20},[],{"issn":2047,"eissn":2048,"title":2049},{"VOID":13},{"VOID":15},{"EN":17},[],[],[],{"volume":2054,"pages":2055,"issue":2057},{"VOID":27},{"VOID":2056},"93-114",{"VOID":112},748,{"total":2058,"publishYear":20,"statisticByYear":2060},{"2012":2061,"2013":516,"2014":2062,"2015":2063,"2016":511,"2017":2064,"2018":520,"2019":2065,"2020":2066,"2021":442,"2022":2067,"2023":443,"2024":518},48,46,30,44,54,56,49,"2006-06-01",2006,[2071,2074,2077,2080,2083,2086,2089,2092,2095,2098,2101,2104,2107,2110,2113,2116,2119,2122,2125,2128,2131,2134,2137,2140,2143,2146,2150,2153,2156,2159,2162,2165,2168,2171,2174,2177,2180,2183,2186,2189,2192,2195,2198,2201,2204,2207,2210,2213,2216,2219,2223,2226,2229,2232,2235,2238,2241,2244,2247,2250,2253,2256,2259,2262,2265,2268,2271,2274,2277,2280,2284,2287,2291,2294,2297,2300,2303,2306,2309,2312,2315,2318,2321,2324,2327,2330,2333,2336,2339,2342,2345,2348,2351,2354,2357,2360,2363,2366,2369,2372,2375,2378,2381,2384,2387,2390,2393,2396,2399,2402],{"id":20,"text":2072,"url":20,"identifiers":2073},"10.1101\u002Fgad.1220104",{"doi":2072},{"id":20,"text":2075,"url":20,"identifiers":2076},"10.1093\u002Femboj\u002F19.15.3888",{"doi":2075},{"id":20,"text":2078,"url":20,"identifiers":2079},"10.1016\u002Fj.tcb.2005.08.004",{"doi":2078},{"id":20,"text":2081,"url":20,"identifiers":2082},"10.1016\u002FS0022-2836(03)00178-5",{"doi":2081},{"id":20,"text":2084,"url":20,"identifiers":2085},"10.1002\u002Fpro.5560061001",{"doi":2084},{"id":20,"text":2087,"url":20,"identifiers":2088},"10.1038\u002F35001629",{"doi":2087},{"id":20,"text":2090,"url":20,"identifiers":2091},"10.1016\u002Fj.molcel.2004.11.038",{"doi":2090},{"id":20,"text":2093,"url":20,"identifiers":2094},"10.1016\u002Fj.febslet.2004.11.038",{"doi":2093},{"id":20,"text":2096,"url":20,"identifiers":2097},"10.1038\u002Fnature02585",{"doi":2096},{"id":20,"text":2099,"url":20,"identifiers":2100},"10.1016\u002FS0014-5793(03)01107-4",{"doi":2099},{"id":20,"text":2102,"url":20,"identifiers":2103},"10.1002\u002Fbies.950170710",{"doi":2102},{"id":20,"text":2105,"url":20,"identifiers":2106},"10.1016\u002Fj.sbi.2005.01.003",{"doi":2105},{"id":20,"text":2108,"url":20,"identifiers":2109},"10.1093\u002Femboj\u002Fcdf308",{"doi":2108},{"id":20,"text":2111,"url":20,"identifiers":2112},"10.1074\u002Fjbc.M210511200",{"doi":2111},{"id":20,"text":2114,"url":20,"identifiers":2115},"10.1038\u002Fnrm949",{"doi":2114},{"id":20,"text":2117,"url":20,"identifiers":2118},"10.1016\u002Fj.str.2004.11.014",{"doi":2117},{"id":20,"text":2120,"url":20,"identifiers":2121},"10.1038\u002Fnsb972",{"doi":2120},{"id":20,"text":2123,"url":20,"identifiers":2124},"10.1016\u002FS0959-437X(96)80051-7",{"doi":2123},{"id":20,"text":2126,"url":20,"identifiers":2127},"10.1016\u002FS0014-5793(02)03179-4",{"doi":2126},{"id":20,"text":2129,"url":20,"identifiers":2130},"10.1042\u002FBST0320715",{"doi":2129},{"id":20,"text":2132,"url":20,"identifiers":2133},"10.1007\u002FBF00990967",{"doi":2132},{"id":20,"text":2135,"url":20,"identifiers":2136},"10.1093\u002Femboj\u002Fcdf496",{"doi":2135},{"id":20,"text":2138,"url":20,"identifiers":2139},"10.1074\u002Fjbc.M409695200",{"doi":2138},{"id":20,"text":2141,"url":20,"identifiers":2142},"10.1006\u002Fjmbi.2001.4834",{"doi":2141},{"id":20,"text":2144,"url":20,"identifiers":2145},"10.1016\u002Fj.jsb.2003.11.020",{"doi":2144},{"id":20,"text":2147,"url":20,"identifiers":2148},"Frohlich KU, 2001, J. Cell Sci., 114, 1601, 10.1242\u002Fjcs.114.9.1601",{"doi":2149},"10.1242\u002Fjcs.114.9.1601",{"id":20,"text":2151,"url":20,"identifiers":2152},"10.1016\u002Fj.cell.2004.09.017",{"doi":2151},{"id":20,"text":2154,"url":20,"identifiers":2155},"10.1186\u002F1471-2164-3-18",{"doi":2154},{"id":20,"text":2157,"url":20,"identifiers":2158},"10.1038\u002Fnsmb889",{"doi":2157},{"id":20,"text":2160,"url":20,"identifiers":2161},"10.1038\u002F35054586",{"doi":2160},{"id":20,"text":2163,"url":20,"identifiers":2164},"10.1016\u002FS0092-8674(00)80417-1",{"doi":2163},{"id":20,"text":2166,"url":20,"identifiers":2167},"10.1074\u002Fjbc.M103611200",{"doi":2166},{"id":20,"text":2169,"url":20,"identifiers":2170},"10.1038\u002Fnrm1684",{"doi":2169},{"id":20,"text":2172,"url":20,"identifiers":2173},"10.1073\u002Fpnas.212504499",{"doi":2172},{"id":20,"text":2175,"url":20,"identifiers":2176},"10.1016\u002FS0092-8674(00)81578-0",{"doi":2175},{"id":20,"text":2178,"url":20,"identifiers":2179},"10.1126\u002Fscience.286.5440.782",{"doi":2178},{"id":20,"text":2181,"url":20,"identifiers":2182},"10.1093\u002Femboj\u002F21.1.12",{"doi":2181},{"id":20,"text":2184,"url":20,"identifiers":2185},"10.1016\u002FS0022-2836(02)01028-8",{"doi":2184},{"id":20,"text":2187,"url":20,"identifiers":2188},"10.1016\u002FS1097-2765(03)00068-6",{"doi":2187},{"id":20,"text":2190,"url":20,"identifiers":2191},"10.1016\u002Fj.cell.2005.05.024",{"doi":2190},{"id":20,"text":2193,"url":20,"identifiers":2194},"10.1016\u002Fj.cell.2005.04.012",{"doi":2193},{"id":20,"text":2196,"url":20,"identifiers":2197},"10.1016\u002FS0065-3233(01)59013-0",{"doi":2196},{"id":20,"text":2199,"url":20,"identifiers":2200},"10.1016\u002Fj.jsb.2003.10.007",{"doi":2199},{"id":20,"text":2202,"url":20,"identifiers":2203},"10.1146\u002Fannurev.micro.59.030804.121316",{"doi":2202},{"id":20,"text":2205,"url":20,"identifiers":2206},"10.1016\u002Fj.jsb.2003.10.010",{"doi":2205},{"id":20,"text":2208,"url":20,"identifiers":2209},"10.1093\u002Fnar\u002Fgkh828",{"doi":2208},{"id":20,"text":2211,"url":20,"identifiers":2212},"10.1016\u002FS0969-2126(03)00152-7",{"doi":2211},{"id":20,"text":2214,"url":20,"identifiers":2215},"10.1016\u002FS0092-8674(01)00463-9",{"doi":2214},{"id":20,"text":2217,"url":20,"identifiers":2218},"10.1016\u002FS0092-8674(01)00462-7",{"doi":2217},{"id":20,"text":2220,"url":20,"identifiers":2221},"Kaguni JM, 1997, Mol. Cell, 7, 145, 10.1016\u002FS1016-8478(23)13273-0",{"doi":2222},"10.1016\u002FS1016-8478(23)13273-0",{"id":20,"text":2224,"url":20,"identifiers":2225},"10.1093\u002Femboj\u002F20.15.4253",{"doi":2224},{"id":20,"text":2227,"url":20,"identifiers":2228},"10.1016\u002FS0092-8674(03)00612-3",{"doi":2227},{"id":20,"text":2230,"url":20,"identifiers":2231},"10.1016\u002FS0969-2126(02)00806-7",{"doi":2230},{"id":20,"text":2233,"url":20,"identifiers":2234},"10.1016\u002F0300-9084(93)90079-8",{"doi":2233},{"id":20,"text":2236,"url":20,"identifiers":2237},"10.1016\u002FS0968-0004(99)01541-8",{"doi":2236},{"id":20,"text":2239,"url":20,"identifiers":2240},"10.1016\u002FS0955-0674(00)00089-2",{"doi":2239},{"id":20,"text":2242,"url":20,"identifiers":2243},"10.1101\u002Fgad.1125603",{"doi":2242},{"id":20,"text":2245,"url":20,"identifiers":2246},"10.1002\u002Fyea.320080912",{"doi":2245},{"id":20,"text":2248,"url":20,"identifiers":2249},"10.1016\u002Fj.jmb.2003.08.040",{"doi":2248},{"id":20,"text":2251,"url":20,"identifiers":2252},"10.1016\u002Fj.jmb.2004.08.023",{"doi":2251},{"id":20,"text":2254,"url":20,"identifiers":2255},"10.1006\u002Fjmbi.2001.5378",{"doi":2254},{"id":20,"text":2257,"url":20,"identifiers":2258},"10.1016\u002FS0092-8674(00)81593-7",{"doi":2257},{"id":20,"text":2260,"url":20,"identifiers":2261},"10.1038\u002Fnature01691",{"doi":2260},{"id":20,"text":2263,"url":20,"identifiers":2264},"10.1016\u002F0092-8674(95)90528-6",{"doi":2263},{"id":20,"text":2266,"url":20,"identifiers":2267},"10.1016\u002Fj.cell.2005.03.035",{"doi":2266},{"id":20,"text":2269,"url":20,"identifiers":2270},"10.1016\u002FS1097-2765(00)00062-9",{"doi":2269},{"id":20,"text":2272,"url":20,"identifiers":2273},"10.1016\u002FS0959-440X(02)00388-3",{"doi":2272},{"id":20,"text":2275,"url":20,"identifiers":2276},"10.1038\u002Fnature04031",{"doi":2275},{"id":20,"text":2278,"url":20,"identifiers":2279},"Messer W, 2002, FEMS Microbiol. Rev., 26, 355",{},{"id":20,"text":2281,"url":20,"identifiers":2282},"Mizushima T, 2000, Genes Dev., 14, 1631, 10.1101\u002Fgad.14.13.1631",{"doi":2283},"10.1101\u002Fgad.14.13.1631",{"id":20,"text":2285,"url":20,"identifiers":2286},"10.1016\u002Fj.jsb.2003.10.009",{"doi":2285},{"id":20,"text":2288,"url":20,"identifiers":2289},"Neuwald AF, 1999, Genome Res., 9, 27, 10.1101\u002Fgr.9.1.27",{"doi":2290},"10.1101\u002Fgr.9.1.27",{"id":20,"text":2292,"url":20,"identifiers":2293},"10.1016\u002FS0969-2126(02)00855-9",{"doi":2292},{"id":20,"text":2295,"url":20,"identifiers":2296},"10.1016\u002Fj.jsb.2003.11.008",{"doi":2295},{"id":20,"text":2298,"url":20,"identifiers":2299},"10.1093\u002Femboj\u002F20.12.3210",{"doi":2298},{"id":20,"text":2301,"url":20,"identifiers":2302},"10.1074\u002Fjbc.M500035200",{"doi":2301},{"id":20,"text":2304,"url":20,"identifiers":2305},"10.1006\u002Fjmbi.2001.4852",{"doi":2304},{"id":20,"text":2307,"url":20,"identifiers":2308},"10.1038\u002Fnature03465",{"doi":2307},{"id":20,"text":2310,"url":20,"identifiers":2311},"10.1016\u002FS1097-2765(00)00144-1",{"doi":2310},{"id":20,"text":2313,"url":20,"identifiers":2314},"10.1038\u002Fnsb872",{"doi":2313},{"id":20,"text":2316,"url":20,"identifiers":2317},"10.1146\u002Fannurev.biochem.72.121801.161547",{"doi":2316},{"id":20,"text":2319,"url":20,"identifiers":2320},"10.1016\u002Fj.jsb.2003.09.026",{"doi":2319},{"id":20,"text":2322,"url":20,"identifiers":2323},"10.1016\u002Fj.cell.2004.09.020",{"doi":2322},{"id":20,"text":2325,"url":20,"identifiers":2326},"10.1016\u002F0092-8674(87)90221-2",{"doi":2325},{"id":20,"text":2328,"url":20,"identifiers":2329},"10.1073\u002Fpnas.0409646102",{"doi":2328},{"id":20,"text":2331,"url":20,"identifiers":2332},"10.1101\u002Fgad.1170304",{"doi":2331},{"id":20,"text":2334,"url":20,"identifiers":2335},"10.1016\u002Fj.jmb.2004.08.044",{"doi":2334},{"id":20,"text":2337,"url":20,"identifiers":2338},"10.1016\u002FS0092-8674(00)80871-5",{"doi":2337},{"id":20,"text":2340,"url":20,"identifiers":2341},"10.1073\u002Fpnas.250491797",{"doi":2340},{"id":20,"text":2343,"url":20,"identifiers":2344},"10.1016\u002FS0092-8674(00)00166-5",{"doi":2343},{"id":20,"text":2346,"url":20,"identifiers":2347},"10.1038\u002F355374a0",{"doi":2346},{"id":20,"text":2349,"url":20,"identifiers":2350},"10.1046\u002Fj.1365-2958.2001.02378.x",{"doi":2349},{"id":20,"text":2352,"url":20,"identifiers":2353},"10.1074\u002Fjbc.M412060200",{"doi":2352},{"id":20,"text":2355,"url":20,"identifiers":2356},"10.1006\u002Fbbrc.1998.8522",{"doi":2355},{"id":20,"text":2358,"url":20,"identifiers":2359},"10.1074\u002Fjbc.273.49.32421",{"doi":2358},{"id":20,"text":2361,"url":20,"identifiers":2362},"10.1146\u002Fannurev.biochem.68.1.649",{"doi":2361},{"id":20,"text":2364,"url":20,"identifiers":2365},"10.1128\u002Fjb.173.21.6948-6961.1991",{"doi":2364},{"id":20,"text":2367,"url":20,"identifiers":2368},"10.1002\u002Fj.1460-2075.1982.tb01276.x",{"doi":2367},{"id":20,"text":2370,"url":20,"identifiers":2371},"10.1016\u002Fj.jsb.2004.07.003",{"doi":2370},{"id":20,"text":2373,"url":20,"identifiers":2374},"10.1016\u002FS0969-2126(01)00570-6",{"doi":2373},{"id":20,"text":2376,"url":20,"identifiers":2377},"10.1016\u002FS0969-2126(01)00670-0",{"doi":2376},{"id":20,"text":2379,"url":20,"identifiers":2380},"10.1073\u002Fpnas.96.2.441",{"doi":2379},{"id":20,"text":2382,"url":20,"identifiers":2383},"10.1016\u002FS0014-5793(97)00321-9",{"doi":2382},{"id":20,"text":2385,"url":20,"identifiers":2386},"10.1016\u002FS1097-2765(00)80427-X",{"doi":2385},{"id":20,"text":2388,"url":20,"identifiers":2389},"10.1016\u002FS1097-2765(02)00641-X",{"doi":2388},{"id":20,"text":2391,"url":20,"identifiers":2392},"10.1074\u002Fjbc.M308327200",{"doi":2391},{"id":20,"text":2394,"url":20,"identifiers":2395},"10.1038\u002Fnature04002",{"doi":2394},{"id":20,"text":2397,"url":20,"identifiers":2398},"10.1016\u002FS1097-2765(00)00142-8",{"doi":2397},{"id":20,"text":2400,"url":20,"identifiers":2401},"10.1038\u002F1843",{"doi":2400},{"id":20,"text":2403,"url":20,"identifiers":2404},"10.1093\u002Fembo-reports\u002Fkvf160",{"doi":2403},{"id":2406,"createTime":2407,"updateTime":2407,"relativeEntities":2408,"slug":2409,"properties":2410,"entityType":48,"verifyStatus":49,"verifyTime":2407,"verifyNote":50,"syncStatus":19,"languages":2424,"translateLanguages":20,"viewCount":21,"primaryUrl":2425,"fullTextUrl":20,"authors":2426,"publicationType":95,"publisherRelationship":2487,"citationCount":2502,"citationInfo":2503,"publishDate":2068,"publishYear":2069,"citationAnalyzeStatus":19,"lastCitationAnalyze":20,"indexDatabases":20,"openAccess":20,"references":2507,"isForceReanalyzing":360},"91196e89-3742-429e-a959-92f6619b3511","2024-09-19T20:42:33.231+00:00",[],"ELECTRON-TOMOGRAPHY-OF-MEMBRANE-BOUND-CELLULAR-ORGANELLES",{"mag":2411,"keywords":2413,"openalex":2414,"abstract":2416,"title":2418,"pm":2420,"doi":2422},{"VOID":2412},"2147313835",{},{"VOID":2415},"W2147313835",{"EN":2417},"\u003Cjats:p> Electron microscope tomography produces three-dimensional reconstructions and has been used to image organelles both isolated and in situ, providing new insight into their structure and function. It is analogous to the various tomographies used in medical imaging. Compared with light microscopy, electron tomography offers an improvement in resolution of 30- to 80-fold and currently ranges from 3 to 8 nm, thus filling the gap between high-resolution structure determinations of isolated macromolecules and larger-scale studies on cells and tissues by light microscopy. Here, we provide an introduction to electron tomography and applications of the method in characterizing organelle architecture that also show its power for suggesting functional significance. Further improvements in labeling modalities, imaging tools, specimen preparation, and reconstruction algorithms promise to increase the quality and breadth of reconstructions by electron tomography and eventually to allow the mapping of the cellular proteomes onto detailed three-dimensional models of cellular structure. \u003C\u002Fjats:p>",{"EN":2419},"ELECTRON TOMOGRAPHY OF MEMBRANE-BOUND CELLULAR ORGANELLES",{"VOID":2421},"16689634",{"VOID":2423},"10.1146\u002Fannurev.biophys.35.040405.102039",[52],"https:\u002F\u002Fwww.annualreviews.org\u002Fdoi\u002F10.1146\u002Fannurev.biophys.35.040405.102039",[2427,2450,2467],{"id":2428,"sortIndex":2429,"researcher":20,"roles":2430,"affiliations":2431,"properties":2443},"723dd323-4fbb-42ef-8915-e748934dfb41",2,[],[2432],{"id":2433,"sortIndex":21,"affiliation":2434,"properties":20},"bd854c73-784b-4c3b-b42b-1b660c58705a",{"id":2435,"createTime":2436,"updateTime":2437,"relativeEntities":2438,"slug":2439,"properties":2440,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"229ccd71-ef26-4385-a803-d0730efdd961","2023-12-23T07:18:01.725+00:00","2024-09-19T20:42:33.262+00:00",[],"National-Center-for-Microscopy-and-Imaging-Research-University-of-California-San-Diego-La-Jolla-California-92093-0608",{"title":2441},{"VI":2442},"National Center for Microscopy and Imaging Research, University of California San Diego, La Jolla, California 92093-0608",{"openalex":2444,"orcid":2446,"title":2448},{"VOID":2445},"A5051156147",{"VOID":2447},"https:\u002F\u002Forcid.org\u002F0000-0001-8893-8455",{"EN":2449},"Mark H. Ellisman",{"id":2451,"sortIndex":57,"researcher":20,"roles":2452,"affiliations":2453,"properties":2460},"c05a63dc-9b40-4cab-95ca-f1c45e3c45df",[],[2454],{"id":2455,"sortIndex":21,"affiliation":2456,"properties":20},"cb17b3f3-7565-4607-b3f4-b719df68ff3c",{"id":2435,"createTime":2436,"updateTime":2437,"relativeEntities":2457,"slug":2439,"properties":2458,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},[],{"title":2459},{"VI":2442},{"openalex":2461,"orcid":2463,"title":2465},{"VOID":2462},"A5033306591",{"VOID":2464},"https:\u002F\u002Forcid.org\u002F0000-0002-1834-6646",{"EN":2466},"Guy Perkins",{"id":2468,"sortIndex":21,"researcher":20,"roles":2469,"affiliations":2470,"properties":2482},"5253acf3-ee16-46d9-878e-024b91d04d1d",[],[2471],{"id":2472,"sortIndex":21,"affiliation":2473,"properties":20},"c15de95f-0746-4a98-93af-8e4cc5b8689c",{"id":2474,"createTime":2475,"updateTime":2476,"relativeEntities":2477,"slug":2478,"properties":2479,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"4cfaac61-8c6b-40dd-93c4-8efcb6e38e60","2024-01-13T16:15:28.610+00:00","2024-09-19T20:42:33.249+00:00",[],"Department-of-Biology-San-Diego-State-University-San-Diego-California-92182-4614",{"title":2480},{"VI":2481},"Department of Biology, San Diego State University, San Diego, California, 92182-4614",{"openalex":2483,"title":2485},{"VOID":2484},"A5104046888",{"EN":2486},"Terrence Frey",{"url":20,"publisher":2488,"properties":2497},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":2489,"slug":10,"properties":2490,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":2494,"manageAffiliations":2495,"indexDatabases":2496,"url":20,"thumbnailPath":20,"statistic":20,"gsStatistic":20,"type":20,"analyzePriority":20},[],{"issn":2491,"eissn":2492,"title":2493},{"VOID":13},{"VOID":15},{"EN":17},[],[],[],{"volume":2498,"pages":2499,"issue":2501},{"VOID":27},{"VOID":2500},"199-224",{"VOID":112},101,{"total":2502,"publishYear":20,"statisticByYear":2504},{"2012":121,"2013":2505,"2014":122,"2015":2506,"2016":124,"2017":124,"2018":2429,"2019":124,"2020":2429,"2021":2429,"2022":2429,"2023":2429,"2024":57},6,3,[2508,2511,2514,2517,2520,2523,2526,2529,2532,2535,2538,2541,2544,2547,2550,2553,2556,2559,2562,2565,2569,2572,2575,2578,2581,2584,2587,2590,2593,2596,2599,2602,2605,2608,2611,2614,2617,2620,2623,2626,2629,2632,2635,2638,2641,2644,2647,2650,2654,2657,2660,2663,2666,2669,2672,2675,2678,2681,2684,2687,2690,2693,2696,2699,2702,2705,2708,2711,2714,2717,2720,2723,2726,2729,2732,2735,2738,2741,2744,2747,2750,2753,2756,2759,2762,2765,2768,2771,2774,2777,2780,2783,2786,2789,2792,2795,2798,2801,2804,2807,2810,2813,2816,2819,2822,2825,2828,2831,2834,2837,2840,2843,2846,2849],{"id":20,"text":2509,"url":20,"identifiers":2510},"10.1016\u002Fj.jsb.2004.03.010",{"doi":2509},{"id":20,"text":2512,"url":20,"identifiers":2513},"10.1016\u002Fj.jsb.2003.09.037",{"doi":2512},{"id":20,"text":2515,"url":20,"identifiers":2516},"10.1016\u002FS0959-440X(02)00378-0",{"doi":2515},{"id":20,"text":2518,"url":20,"identifiers":2519},"10.1016\u002Fj.febslet.2004.10.102",{"doi":2518},{"id":20,"text":2521,"url":20,"identifiers":2522},"10.1126\u002Fscience.1104808",{"doi":2521},{"id":20,"text":2524,"url":20,"identifiers":2525},"10.1073\u002Fpnas.230282097",{"doi":2524},{"id":20,"text":2527,"url":20,"identifiers":2528},"10.1016\u002Fj.jsb.2005.05.004",{"doi":2527},{"id":20,"text":2530,"url":20,"identifiers":2531},"10.1016\u002Fj.jsb.2004.08.005",{"doi":2530},{"id":20,"text":2533,"url":20,"identifiers":2534},"10.1016\u002FS1047-8477(02)00013-8",{"doi":2533},{"id":20,"text":2536,"url":20,"identifiers":2537},"10.1098\u002Frspa.1970.0119",{"doi":2536},{"id":20,"text":2539,"url":20,"identifiers":2540},"10.1016\u002FS0022-5320(66)80027-8",{"doi":2539},{"id":20,"text":2542,"url":20,"identifiers":2543},"10.1007\u002Fs007090200017",{"doi":2542},{"id":20,"text":2545,"url":20,"identifiers":2546},"10.1006\u002Fjsbi.1999.4147",{"doi":2545},{"id":20,"text":2548,"url":20,"identifiers":2549},"10.1017\u002FS0033583500004297",{"doi":2548},{"id":20,"text":2551,"url":20,"identifiers":2552},"10.1073\u002Fpnas.0408870102",{"doi":2551},{"id":20,"text":2554,"url":20,"identifiers":2555},"10.1016\u002Fj.jsb.2003.09.010",{"doi":2554},{"id":20,"text":2557,"url":20,"identifiers":2558},"10.1073\u002Fpnas.172520299",{"doi":2557},{"id":20,"text":2560,"url":20,"identifiers":2561},"10.1016\u002Fj.sbi.2004.04.003",{"doi":2560},{"id":20,"text":2563,"url":20,"identifiers":2564},"10.1007\u002F978-1-4757-2163-8",{"doi":2563},{"id":20,"text":2566,"url":20,"identifiers":2567},"Frank J. 1996. Three-Dimensional Electron Microscopy of Macromolecular Assemblies. San Diego: Academic. 342pp.",{"doi":2568},"10.1016\u002FB978-012265040-6\u002F50002-3",{"id":20,"text":2570,"url":20,"identifiers":2571},"10.1006\u002Fjsbi.1996.0030",{"doi":2570},{"id":20,"text":2573,"url":20,"identifiers":2574},"10.1016\u002FS1047-8477(02)00019-9",{"doi":2573},{"id":20,"text":2576,"url":20,"identifiers":2577},"10.1016\u002FS0005-2728(02)00278-5",{"doi":2576},{"id":20,"text":2579,"url":20,"identifiers":2580},"10.1016\u002FS0968-0004(00)01609-1",{"doi":2579},{"id":20,"text":2582,"url":20,"identifiers":2583},"10.1126\u002Fscience.1068793",{"doi":2582},{"id":20,"text":2585,"url":20,"identifiers":2586},"10.1038\u002Fnmeth791",{"doi":2585},{"id":20,"text":2588,"url":20,"identifiers":2589},"10.1016\u002FS0014-5793(03)00633-1",{"doi":2588},{"id":20,"text":2591,"url":20,"identifiers":2592},"10.1126\u002Fscience.1099320",{"doi":2591},{"id":20,"text":2594,"url":20,"identifiers":2595},"Grethe JS, 2005, Stud. Health Technol. Inform., 112, 100",{},{"id":20,"text":2597,"url":20,"identifiers":2598},"10.1126\u002Fscience.281.5374.269",{"doi":2597},{"id":20,"text":2600,"url":20,"identifiers":2601},"10.1126\u002Fscience.1090284",{"doi":2600},{"id":20,"text":2603,"url":20,"identifiers":2604},"10.1083\u002Fjcb.30.2.269",{"doi":2603},{"id":20,"text":2606,"url":20,"identifiers":2607},"10.1006\u002Fjsbi.1999.4095",{"doi":2606},{"id":20,"text":2609,"url":20,"identifiers":2610},"10.1038\u002F35054000",{"doi":2609},{"id":20,"text":2612,"url":20,"identifiers":2613},"10.1073\u002Fpnas.0333594100",{"doi":2612},{"id":20,"text":2615,"url":20,"identifiers":2616},"10.1515\u002Fznc-1973-11-1209",{"doi":2615},{"id":20,"text":2618,"url":20,"identifiers":2619},"10.1016\u002FS1047-8477(02)00034-5",{"doi":2618},{"id":20,"text":2621,"url":20,"identifiers":2622},"10.1091\u002Fmbc.E04-08-0697",{"doi":2621},{"id":20,"text":2624,"url":20,"identifiers":2625},"10.1083\u002Fjcb.147.4.809",{"doi":2624},{"id":20,"text":2627,"url":20,"identifiers":2628},"10.1006\u002Fjsbi.1996.0013",{"doi":2627},{"id":20,"text":2630,"url":20,"identifiers":2631},"10.1083\u002Fjcb.127.1.29",{"doi":2630},{"id":20,"text":2633,"url":20,"identifiers":2634},"10.1083\u002Fjcb.144.6.1135",{"doi":2633},{"id":20,"text":2636,"url":20,"identifiers":2637},"10.1091\u002Fmbc.01-12-0593",{"doi":2636},{"id":20,"text":2639,"url":20,"identifiers":2640},"10.1016\u002Fj.ultramic.2004.03.002",{"doi":2639},{"id":20,"text":2642,"url":20,"identifiers":2643},"10.1006\u002Fjsbi.1997.3917",{"doi":2642},{"id":20,"text":2645,"url":20,"identifiers":2646},"10.1146\u002Fannurev.biochem.73.011303.074112",{"doi":2645},{"id":20,"text":2648,"url":20,"identifiers":2649},"10.1023\u002FA:1005562109678",{"doi":2648},{"id":20,"text":2651,"url":20,"identifiers":2652},"Mannella CA. 2006. The relevance of mitochondrial membrane topology to mitochondrial function. Biochim. Biophys. Acta. 1762:140–47",{"doi":2653},"10.1016\u002Fj.bbadis.2005.07.001",{"id":20,"text":2655,"url":20,"identifiers":2656},"10.1002\u002Fbiof.5520080309",{"doi":2655},{"id":20,"text":2658,"url":20,"identifiers":2659},"Mannella CA, 1999, Proceedings of Microscopy and Microanalysis, 416",{},{"id":20,"text":2661,"url":20,"identifiers":2662},"10.1016\u002FS0968-0004(96)30050-9",{"doi":2661},{"id":20,"text":2664,"url":20,"identifiers":2665},"10.1002\u002Fjemt.1070270403",{"doi":2664},{"id":20,"text":2667,"url":20,"identifiers":2668},"10.1080\u002F15216540152845885",{"doi":2667},{"id":20,"text":2670,"url":20,"identifiers":2671},"Marco S, 2004, Biochemistry, 69, 1219",{},{"id":20,"text":2673,"url":20,"identifiers":2674},"10.1016\u002Fj.bbamcr.2005.04.002",{"doi":2673},{"id":20,"text":2676,"url":20,"identifiers":2677},"10.1073\u002Fpnas.051631998",{"doi":2676},{"id":20,"text":2679,"url":20,"identifiers":2680},"10.1042\u002FBST0290461",{"doi":2679},{"id":20,"text":2682,"url":20,"identifiers":2683},"10.1073\u002Fpnas.0401242101",{"doi":2682},{"id":20,"text":2685,"url":20,"identifiers":2686},"10.1038\u002Fnn1229",{"doi":2685},{"id":20,"text":2688,"url":20,"identifiers":2689},"10.1016\u002FS1047-8477(02)00006-0",{"doi":2688},{"id":20,"text":2691,"url":20,"identifiers":2692},"10.1002\u002F1098-1063(2000)10:5\u003C610::AID-HIPO12>3.0.CO;2-E",{"doi":2691},{"id":20,"text":2694,"url":20,"identifiers":2695},"10.1385\u002FNI:1:4:379",{"doi":2694},{"id":20,"text":2697,"url":20,"identifiers":2698},"10.1523\u002FJNEUROSCI.13-11-04636.1993",{"doi":2697},{"id":20,"text":2700,"url":20,"identifiers":2701},"10.1006\u002Fjsbi.1997.3919",{"doi":2700},{"id":20,"text":2703,"url":20,"identifiers":2704},"10.1016\u002FS0091-679X(08)61976-7",{"doi":2703},{"id":20,"text":2706,"url":20,"identifiers":2707},"10.1177\u002F002215540104900502",{"doi":2706},{"id":20,"text":2709,"url":20,"identifiers":2710},"10.1016\u002FS1047-8477(02)00020-5",{"doi":2709},{"id":20,"text":2712,"url":20,"identifiers":2713},"10.1083\u002Fjcb.153.6.F25",{"doi":2712},{"id":20,"text":2715,"url":20,"identifiers":2716},"10.1016\u002Fj.tcb.2004.11.009",{"doi":2715},{"id":20,"text":2718,"url":20,"identifiers":2719},"10.1126\u002Fscience.1076184",{"doi":2718},{"id":20,"text":2721,"url":20,"identifiers":2722},"10.1016\u002FS1534-5807(03)00294-6",{"doi":2721},{"id":20,"text":2724,"url":20,"identifiers":2725},"10.1091\u002Fmbc.E02-10-0697",{"doi":2724},{"id":20,"text":2727,"url":20,"identifiers":2728},"Morau II, 2000, Biophys. J., 78, 194A",{},{"id":20,"text":2730,"url":20,"identifiers":2731},"10.1046\u002Fj.1365-2818.2003.01238.x",{"doi":2730},{"id":20,"text":2733,"url":20,"identifiers":2734},"10.1006\u002Fjsbi.1999.4204",{"doi":2733},{"id":20,"text":2736,"url":20,"identifiers":2737},"10.1016\u002Fj.jsb.2004.10.006",{"doi":2736},{"id":20,"text":2739,"url":20,"identifiers":2740},"10.1006\u002Fjsbi.1997.3915",{"doi":2739},{"id":20,"text":2742,"url":20,"identifiers":2743},"10.1105\u002Ftpc.13.9.2033",{"doi":2742},{"id":20,"text":2745,"url":20,"identifiers":2746},"10.1091\u002Fmbc.E02-11-0755",{"doi":2745},{"id":20,"text":2748,"url":20,"identifiers":2749},"10.1083\u002Fjcb.200304035",{"doi":2748},{"id":20,"text":2751,"url":20,"identifiers":2752},"10.1091\u002Fmbc.10.6.2017",{"doi":2751},{"id":20,"text":2754,"url":20,"identifiers":2755},"10.1002\u002Far.1091140304",{"doi":2754},{"id":20,"text":2757,"url":20,"identifiers":2758},"10.1016\u002FS1047-8477(02)00008-4",{"doi":2757},{"id":20,"text":2760,"url":20,"identifiers":2761},"10.1006\u002Fjsbi.1997.3885",{"doi":2760},{"id":20,"text":2763,"url":20,"identifiers":2764},"Perkins GA, 2003, Mol. Vis., 9, 60",{},{"id":20,"text":2766,"url":20,"identifiers":2767},"10.1016\u002FS0968-4328(99)00065-7",{"doi":2766},{"id":20,"text":2769,"url":20,"identifiers":2770},"10.1006\u002Fjsbi.1997.3920",{"doi":2769},{"id":20,"text":2772,"url":20,"identifiers":2773},"10.1078\u002F0171-9335-00149",{"doi":2772},{"id":20,"text":2775,"url":20,"identifiers":2776},"10.1023\u002FA:1020586012561",{"doi":2775},{"id":20,"text":2778,"url":20,"identifiers":2779},"10.1088\u002F1478-3967\u002F2\u002F1\u002F009",{"doi":2778},{"id":20,"text":2781,"url":20,"identifiers":2782},"10.1002\u002Far.a.20019",{"doi":2781},{"id":20,"text":2784,"url":20,"identifiers":2785},"Renken C. 2004. The Structure of Mitochondria. San Diego, CA: San Diego State Univ. Press. 200pp.",{},{"id":20,"text":2787,"url":20,"identifiers":2788},"10.1016\u002FS1047-8477(02)00012-6",{"doi":2787},{"id":20,"text":2790,"url":20,"identifiers":2791},"10.1016\u002Fj.str.2004.07.022",{"doi":2790},{"id":20,"text":2793,"url":20,"identifiers":2794},"10.1016\u002FS1534-5807(01)00116-2",{"doi":2793},{"id":20,"text":2796,"url":20,"identifiers":2797},"10.1105\u002Ftpc.017749",{"doi":2796},{"id":20,"text":2799,"url":20,"identifiers":2800},"10.1016\u002FS0074-7696(08)62578-4",{"doi":2799},{"id":20,"text":2802,"url":20,"identifiers":2803},"10.1006\u002Fjsbi.1996.0081",{"doi":2802},{"id":20,"text":2805,"url":20,"identifiers":2806},"10.1016\u002Fj.jsb.2004.06.006",{"doi":2805},{"id":20,"text":2808,"url":20,"identifiers":2809},"10.1006\u002Fnimg.1994.1008",{"doi":2808},{"id":20,"text":2811,"url":20,"identifiers":2812},"10.1126\u002Fscience.298.5602.2297",{"doi":2811},{"id":20,"text":2814,"url":20,"identifiers":2815},"10.1016\u002FS0962-8924(03)00023-0",{"doi":2814},{"id":20,"text":2817,"url":20,"identifiers":2818},"10.1146\u002Fannurev.biophys.33.110502.140339",{"doi":2817},{"id":20,"text":2820,"url":20,"identifiers":2821},"10.1016\u002FS0304-3991(99)00172-2",{"doi":2820},{"id":20,"text":2823,"url":20,"identifiers":2824},"10.1016\u002FS0092-8674(00)81528-7",{"doi":2823},{"id":20,"text":2826,"url":20,"identifiers":2827},"10.1038\u002Fncb1180",{"doi":2826},{"id":20,"text":2829,"url":20,"identifiers":2830},"Vance JE, 1996, Anticancer Res., 16, 1333",{},{"id":20,"text":2832,"url":20,"identifiers":2833},"10.1016\u002FS1047-8477(02)00009-6",{"doi":2832},{"id":20,"text":2835,"url":20,"identifiers":2836},"10.1083\u002Fjcb.150.5.1027",{"doi":2835},{"id":20,"text":2838,"url":20,"identifiers":2839},"10.1073\u002Fpnas.0403767101",{"doi":2838},{"id":20,"text":2841,"url":20,"identifiers":2842},"10.1016\u002FS1047-8477(03)00120-5",{"doi":2841},{"id":20,"text":2844,"url":20,"identifiers":2845},"10.1016\u002Fj.jsb.2004.02.005",{"doi":2844},{"id":20,"text":2847,"url":20,"identifiers":2848},"10.1046\u002Fj.0022-2720.2001.00987.x",{"doi":2847},{"id":20,"text":2850,"url":20,"identifiers":2851},"10.1046\u002Fj.1365-2818.2003.01244.x",{"doi":2850},{"id":2853,"createTime":2854,"updateTime":2854,"relativeEntities":2855,"slug":2856,"properties":2857,"entityType":48,"verifyStatus":49,"verifyTime":2869,"verifyNote":50,"syncStatus":19,"languages":2870,"translateLanguages":20,"viewCount":21,"primaryUrl":2871,"fullTextUrl":20,"authors":2872,"publicationType":95,"publisherRelationship":2958,"citationCount":2974,"citationInfo":2975,"publishDate":2979,"publishYear":2980,"citationAnalyzeStatus":19,"lastCitationAnalyze":20,"indexDatabases":20,"openAccess":20,"references":2981,"isForceReanalyzing":360},"7f836365-1dfc-4421-8abd-9c755599ce92","2024-09-03T19:36:46.977+00:00",[],"THE-PROTEASOME",{"keywords":2858,"openalex":2859,"abstract":2861,"title":2863,"pm":2865,"doi":2867},{},{"VOID":2860},"W4255738047",{"EN":2862},"\u003Cjats:p>▪ Abstract  Proteasomes are large multisubunit proteases that are found in the cytosol, both free and attached to the endoplasmic reticulum, and in the nucleus of eukaryotic cells. Their ubiquitous presence and high abundance in these compartments reflects their central role in cellular protein turnover. Proteasomes recognize, unfold, and digest protein substrates that have been marked for degradation by the attachment of a ubiquitin moiety. Individual subcomplexes of the complete 26S proteasome are involved in these different tasks: The ATP-dependent 19S caps are believed to unfold substrates and feed them to the actual protease, the 20S proteasome. This core particle appears to be more ancient than the ubiquitin system. Both prokaryotic and archaebacterial ancestors have been identified. Crystal structures are now available for the E. coli proteasome homologue and the T. acidophilum and S. cerevisiae 20S proteasomes. All three enzymes are cylindrical particles that have their active sites on the inner walls of a large central cavity. They share the fold and a novel catalytic mechanism with an N-terminal nucleophilic threonine, which places them in the family of Ntn (N terminal nucleophile) hydrolases. Evolution has added complexity to the comparatively simple prokaryotic prototype. This minimal proteasome is a homododecamer made from two hexameric rings stacked head to head. Its heptameric version is the catalytic core of archaebacterial proteasomes, where it is sandwiched between two inactive antichambers that are made up from a different subunit. In eukaryotes, both subunits have diverged into seven different subunits each, which are present in the particle in unique locations such that a complex dimer is formed that has six active sites with three major specificities that can be attributed to individual subunits. Genetic, biochemical, and high-resolution electron microscopy data, but no crystal structures, are available for the 19S caps. A first step toward a mechanistic understanding of proteasome activation and regulation has been made with the elucidation of the X-ray structure of the alternative, mammalian proteasome activator PA28.\u003C\u002Fjats:p>",{"EN":2864},"THE PROTEASOME",{"VOID":2866},"10410804",{"VOID":2868},"10.1146\u002Fannurev.biophys.28.1.295","2024-09-03T19:36:46.976+00:00",[52],"https:\u002F\u002Fwww.annualreviews.org\u002Fdoi\u002F10.1146\u002Fannurev.biophys.28.1.295",[2873,2894,2909,2924,2941],{"id":2874,"sortIndex":2429,"researcher":20,"roles":2875,"affiliations":2876,"properties":2887},"6089c421-dac4-46ed-8202-223709afef02",[],[2877],{"id":2878,"sortIndex":21,"affiliation":2879,"properties":20},"42e6e39c-ac60-4151-8f84-d978b9fa571b",{"id":2880,"createTime":2881,"updateTime":2881,"relativeEntities":2882,"slug":2883,"properties":2884,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"6186bc0b-ceff-40d7-a6ac-93c8d96f1a72","2024-09-03T19:36:47.091+00:00",[],"Max-Planck-Institut-f%C3%BCr-Biochemie-Am-Klopferspitz-18a-Martinsried-Planegg-82152-Germany-",{"title":2885},{"EN":2886},"Max-Planck-Institut für Biochemie, Am Klopferspitz 18a, Martinsried\u002FPlanegg, 82152 Germany;",{"openalex":2888,"orcid":2890,"title":2892},{"VOID":2889},"A5057720807",{"VOID":2891},"https:\u002F\u002Forcid.org\u002F0000-0002-1660-340X",{"EN":2893},"M. Groll",{"id":2895,"sortIndex":2506,"researcher":20,"roles":2896,"affiliations":2897,"properties":2904},"a19b1b69-c272-4783-9a07-4aa382338791",[],[2898],{"id":2899,"sortIndex":21,"affiliation":2900,"properties":20},"f156e5e3-8357-4b36-9f54-a0d234f44c7e",{"id":2880,"createTime":2881,"updateTime":2881,"relativeEntities":2901,"slug":2883,"properties":2902,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},[],{"title":2903},{"EN":2886},{"openalex":2905,"title":2907},{"VOID":2906},"A5044019451",{"EN":2908},"Claudia Hartmann",{"id":2910,"sortIndex":57,"researcher":20,"roles":2911,"affiliations":2912,"properties":2919},"ee01f814-3d5b-4eca-a492-69569c72be8d",[],[2913],{"id":2914,"sortIndex":21,"affiliation":2915,"properties":20},"7f0664f3-affc-4dd5-afda-8dbe74b99fb3",{"id":2880,"createTime":2881,"updateTime":2881,"relativeEntities":2916,"slug":2883,"properties":2917,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},[],{"title":2918},{"EN":2886},{"openalex":2920,"title":2922},{"VOID":2921},"A5004285139",{"EN":2923},"Lars Ditzel",{"id":2925,"sortIndex":21,"researcher":20,"roles":2926,"affiliations":2927,"properties":2934},"6e0fa6a1-4278-4c7a-a202-37d2350fcaa7",[],[2928],{"id":2929,"sortIndex":21,"affiliation":2930,"properties":20},"1f629a83-c002-4a21-8e73-6c3d96c6fafb",{"id":2880,"createTime":2881,"updateTime":2881,"relativeEntities":2931,"slug":2883,"properties":2932,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},[],{"title":2933},{"EN":2886},{"openalex":2935,"orcid":2937,"title":2939},{"VOID":2936},"A5068480855",{"VOID":2938},"https:\u002F\u002Forcid.org\u002F0000-0001-7884-4463",{"EN":2940},"Matthias Bochtler",{"id":2942,"sortIndex":124,"researcher":20,"roles":2943,"affiliations":2944,"properties":2951},"c0329f9d-96cc-4873-b6fd-07a70f1bf479",[],[2945],{"id":2946,"sortIndex":21,"affiliation":2947,"properties":20},"7c275253-f681-4918-ab20-742ea633f995",{"id":2880,"createTime":2881,"updateTime":2881,"relativeEntities":2948,"slug":2883,"properties":2949,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},[],{"title":2950},{"EN":2886},{"openalex":2952,"orcid":2954,"title":2956},{"VOID":2953},"A5101832860",{"VOID":2955},"https:\u002F\u002Forcid.org\u002F0000-0002-0133-5334",{"EN":2957},"Robert Huber",{"url":20,"publisher":2959,"properties":2968},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":2960,"slug":10,"properties":2961,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":2965,"manageAffiliations":2966,"indexDatabases":2967,"url":20,"thumbnailPath":20,"statistic":20,"gsStatistic":20,"type":20,"analyzePriority":20},[],{"issn":2962,"eissn":2963,"title":2964},{"VOID":13},{"VOID":15},{"EN":17},[],[],[],{"volume":2969,"pages":2971,"issue":2973},{"VOID":2970},"28",{"VOID":2972},"295-317",{"VOID":112},417,{"total":2974,"publishYear":20,"statisticByYear":2976},{"2012":123,"2013":519,"2014":119,"2015":2977,"2016":122,"2017":2429,"2018":2506,"2019":2505,"2020":2978,"2021":122,"2022":2505,"2023":123,"2024":2506},7,13,"1999-06-01",1999,[2982,2985,2988,2991,2994,2997,3000,3003,3006,3008,3011,3014,3017,3020,3023,3026,3029,3032,3036,3040,3044,3048,3051,3054,3056,3059,3062,3065,3068,3071,3075,3079,3082,3086,3090,3093,3096,3099,3102,3105,3109,3113,3116,3120,3123,3126,3129,3132,3135,3138,3141,3144,3147,3150,3153,3156,3159,3163,3166,3169,3173,3176,3179,3182,3185,3188,3191,3194,3197,3201,3204,3207,3210,3213,3216,3219,3222,3226,3229,3233,3236,3239,3242,3245,3248,3252,3256,3259,3262,3265,3268,3271,3274,3277,3280,3283,3286,3289,3292,3295,3298,3301,3304,3308,3311,3314,3317,3320,3323,3326,3329,3332,3335,3338,3341,3344,3347,3350,3353,3356,3359,3363,3366,3369,3372,3376,3379,3382,3385,3388,3391,3395,3398,3401,3404,3407,3410,3413,3416,3419,3422,3425,3428,3431,3434,3437,3440,3443,3446,3449,3452,3455,3458,3461,3464,3467,3470,3473,3476,3479,3482,3486,3489,3492,3495,3498,3501,3505,3508,3512,3515,3518,3521,3524,3527,3530,3534],{"id":20,"text":2983,"url":20,"identifiers":2984},"10.1006\u002Fjmbi.1997.1334",{"doi":2983},{"id":20,"text":2986,"url":20,"identifiers":2987},"10.1016\u002FS0960-894X(98)00029-8",{"doi":2986},{"id":20,"text":2989,"url":20,"identifiers":2990},"10.1016\u002F0014-5793(95)00492-R",{"doi":2989},{"id":20,"text":2992,"url":20,"identifiers":2993},"10.1074\u002Fjbc.272.3.1791",{"doi":2992},{"id":20,"text":2995,"url":20,"identifiers":2996},"10.1073\u002Fpnas.94.14.7156",{"doi":2995},{"id":20,"text":2998,"url":20,"identifiers":2999},"10.1038\u002F360171a0",{"doi":2998},{"id":20,"text":3001,"url":20,"identifiers":3002},"10.1016\u002FS0092-8674(00)80929-0",{"doi":3001},{"id":20,"text":3004,"url":20,"identifiers":3005},"10.1074\u002Fjbc.273.30.18734",{"doi":3004},{"id":20,"text":2084,"url":20,"identifiers":3007},{"doi":2084},{"id":20,"text":3009,"url":20,"identifiers":3010},"10.1126\u002Fscience.277.5331.1453",{"doi":3009},{"id":20,"text":3012,"url":20,"identifiers":3013},"10.1073\u002Fpnas.94.12.6070",{"doi":3012},{"id":20,"text":3015,"url":20,"identifiers":3016},"10.1073\u002Fpnas.94.13.6629",{"doi":3015},{"id":20,"text":3018,"url":20,"identifiers":3019},"10.1038\u002F378416a0",{"doi":3018},{"id":20,"text":3021,"url":20,"identifiers":3022},"10.1126\u002Fscience.273.5278.1058",{"doi":3021},{"id":20,"text":3024,"url":20,"identifiers":3025},"10.1126\u002Fscience.2538923",{"doi":3024},{"id":20,"text":3027,"url":20,"identifiers":3028},"10.1016\u002FS0092-8674(00)80171-3",{"doi":3027},{"id":20,"text":3030,"url":20,"identifiers":3031},"10.1016\u002F0378-1119(93)90167-2",{"doi":3030},{"id":20,"text":3033,"url":20,"identifiers":3034},"Chu-Ping M, 1992, J. Biol. Chem., 267, 10515, 10.1016\u002FS0021-9258(19)50047-3",{"doi":3035},"10.1016\u002FS0021-9258(19)50047-3",{"id":20,"text":3037,"url":20,"identifiers":3038},"Chu-Ping M, 1994, J. Biol. Chem., 269, 3539, 10.1016\u002FS0021-9258(17)41897-7",{"doi":3039},"10.1016\u002FS0021-9258(17)41897-7",{"id":20,"text":3041,"url":20,"identifiers":3042},"Chu-Ping M, 1993, J. Biol. Chem., 268, 22514, 10.1016\u002FS0021-9258(18)41559-1",{"doi":3043},"10.1016\u002FS0021-9258(18)41559-1",{"id":20,"text":3045,"url":20,"identifiers":3046},"Ciechanover A, 1981, J. Biol. Chem., 257, 2537, 10.1016\u002FS0021-9258(18)34957-3",{"doi":3047},"10.1016\u002FS0021-9258(18)34957-3",{"id":20,"text":3049,"url":20,"identifiers":3050},"10.1073\u002Fpnas.77.3.1365",{"doi":3049},{"id":20,"text":3052,"url":20,"identifiers":3053},"10.1073\u002Fpnas.78.2.761",{"doi":3052},{"id":20,"text":2102,"url":20,"identifiers":3055},{"doi":2102},{"id":20,"text":3057,"url":20,"identifiers":3058},"10.1146\u002Fannurev.bi.65.070196.004101",{"doi":3057},{"id":20,"text":3060,"url":20,"identifiers":3061},"10.1073\u002Fpnas.94.20.10850",{"doi":3060},{"id":20,"text":3063,"url":20,"identifiers":3064},"10.1016\u002F0014-5793(89)81441-3",{"doi":3063},{"id":20,"text":3066,"url":20,"identifiers":3067},"10.1038\u002F32831",{"doi":3066},{"id":20,"text":3069,"url":20,"identifiers":3070},"10.1128\u002FMCB.15.11.6311",{"doi":3069},{"id":20,"text":3072,"url":20,"identifiers":3073},"DeMartino GN, 1979, J. Biol. Chem., 254, 3712, 10.1016\u002FS0021-9258(18)50643-8",{"doi":3074},"10.1016\u002FS0021-9258(18)50643-8",{"id":20,"text":3076,"url":20,"identifiers":3077},"DeMartino GN, 1994, J. Biol. Chem., 269, 20878, 10.1016\u002FS0021-9258(17)31904-X",{"doi":3078},"10.1016\u002FS0021-9258(17)31904-X",{"id":20,"text":3080,"url":20,"identifiers":3081},"10.1074\u002Fjbc.271.6.3112",{"doi":3080},{"id":20,"text":3083,"url":20,"identifiers":3084},"Deveraux Q, 1994, J. Biol. Chem., 269, 7059, 10.1016\u002FS0021-9258(17)37244-7",{"doi":3085},"10.1016\u002FS0021-9258(17)37244-7",{"id":20,"text":3087,"url":20,"identifiers":3088},"Dick LR, 1994, J. Immunol., 152, 3884, 10.4049\u002Fjimmunol.152.8.3884",{"doi":3089},"10.4049\u002Fjimmunol.152.8.3884",{"id":20,"text":3091,"url":20,"identifiers":3092},"10.1016\u002FS0092-8674(00)80097-5",{"doi":3091},{"id":20,"text":3094,"url":20,"identifiers":3095},"10.1006\u002Fjmbi.1998.1818",{"doi":3094},{"id":20,"text":3097,"url":20,"identifiers":3098},"10.1515\u002Fbchm.1997.378.3-4.239",{"doi":3097},{"id":20,"text":3100,"url":20,"identifiers":3101},"10.1038\u002F365262a0",{"doi":3100},{"id":20,"text":3103,"url":20,"identifiers":3104},"10.1073\u002Fpnas.89.11.4986",{"doi":3103},{"id":20,"text":3106,"url":20,"identifiers":3107},"Driscoll J, 1990, J. Biol. Chem., 265, 4789, 10.1016\u002FS0021-9258(19)34041-4",{"doi":3108},"10.1016\u002FS0021-9258(19)34041-4",{"id":20,"text":3110,"url":20,"identifiers":3111},"Dubiel W, 1992, J. Biol. Chem., 267, 22699, 10.1016\u002FS0021-9258(18)50002-8",{"doi":3112},"10.1016\u002FS0021-9258(18)50002-8",{"id":20,"text":3114,"url":20,"identifiers":3115},"10.1016\u002F0014-5793(93)81356-5",{"doi":3114},{"id":20,"text":3117,"url":20,"identifiers":3118},"Dubiel W, 1992, J. Biol. Chem., 267, 22369, 10.1016\u002FS0021-9258(18)41681-X",{"doi":3119},"10.1016\u002FS0021-9258(18)41681-X",{"id":20,"text":3121,"url":20,"identifiers":3122},"10.1038\u002F373264a0",{"doi":3121},{"id":20,"text":3124,"url":20,"identifiers":3125},"10.1016\u002F0014-5793(94)80455-9",{"doi":3124},{"id":20,"text":3127,"url":20,"identifiers":3128},"10.1073\u002Fpnas.74.1.54",{"doi":3127},{"id":20,"text":3130,"url":20,"identifiers":3131},"10.1073\u002Fpnas.86.20.7751",{"doi":3130},{"id":20,"text":3133,"url":20,"identifiers":3134},"10.1126\u002Fscience.8066463",{"doi":3133},{"id":20,"text":3136,"url":20,"identifiers":3137},"10.1126\u002Fscience.7732382",{"doi":3136},{"id":20,"text":3139,"url":20,"identifiers":3140},"10.1016\u002F0014-5793(96)00101-9",{"doi":3139},{"id":20,"text":3142,"url":20,"identifiers":3143},"10.1023\u002FA:1006837600040",{"doi":3142},{"id":20,"text":3145,"url":20,"identifiers":3146},"10.1038\u002F338394a0",{"doi":3145},{"id":20,"text":3148,"url":20,"identifiers":3149},"10.1016\u002F0092-8674(87)90711-2",{"doi":3148},{"id":20,"text":3151,"url":20,"identifiers":3152},"10.1016\u002F0968-0004(85)90108-2",{"doi":3151},{"id":20,"text":3154,"url":20,"identifiers":3155},"10.1126\u002Fscience.7542800",{"doi":3154},{"id":20,"text":3157,"url":20,"identifiers":3158},"10.1016\u002F0022-2836(94)90003-5",{"doi":3157},{"id":20,"text":3160,"url":20,"identifiers":3161},"Fujiwara T, 1990, J. Biol. Chem., 265, 16604, 10.1016\u002FS0021-9258(17)46265-X",{"doi":3162},"10.1016\u002FS0021-9258(17)46265-X",{"id":20,"text":3164,"url":20,"identifiers":3165},"10.1074\u002Fjbc.271.29.17275",{"doi":3164},{"id":20,"text":3167,"url":20,"identifiers":3168},"10.1038\u002F365264a0",{"doi":3167},{"id":20,"text":3170,"url":20,"identifiers":3171},"Ganoth D, 1988, J. Biol. Chem., 263, 12412, 10.1016\u002FS0021-9258(18)37771-8",{"doi":3172},"10.1016\u002FS0021-9258(18)37771-8",{"id":20,"text":3174,"url":20,"identifiers":3175},"10.1038\u002F366358a0",{"doi":3174},{"id":20,"text":3177,"url":20,"identifiers":3178},"10.1128\u002FMCB.18.6.3149",{"doi":3177},{"id":20,"text":3180,"url":20,"identifiers":3181},"10.1038\u002F357375a0",{"doi":3180},{"id":20,"text":3183,"url":20,"identifiers":3184},"10.1006\u002Fjmbi.1994.1113",{"doi":3183},{"id":20,"text":3186,"url":20,"identifiers":3187},"10.1038\u002F381166a0",{"doi":3186},{"id":20,"text":3189,"url":20,"identifiers":3190},"10.1038\u002F386463a0",{"doi":3189},{"id":20,"text":3192,"url":20,"identifiers":3193},"10.1016\u002F0014-5793(91)81256-8",{"doi":3192},{"id":20,"text":3195,"url":20,"identifiers":3196},"10.1096\u002Ffasebj.11.14.9409544",{"doi":3195},{"id":20,"text":3198,"url":20,"identifiers":3199},"Harris CA, 1992, J. Biol. Chem., 267, 6865, 10.1016\u002FS0021-9258(19)50507-5",{"doi":3200},"10.1016\u002FS0021-9258(19)50507-5",{"id":20,"text":3202,"url":20,"identifiers":3203},"10.1016\u002F0014-5793(91)80567-M",{"doi":3202},{"id":20,"text":3205,"url":20,"identifiers":3206},"10.1074\u002Fjbc.272.40.25200",{"doi":3205},{"id":20,"text":3208,"url":20,"identifiers":3209},"10.1002\u002Fj.1460-2075.1991.tb07982.x",{"doi":3208},{"id":20,"text":3211,"url":20,"identifiers":3212},"10.1042\u002Fbj3320749",{"doi":3211},{"id":20,"text":3214,"url":20,"identifiers":3215},"10.1016\u002FS0968-0004(96)10054-2",{"doi":3214},{"id":20,"text":3217,"url":20,"identifiers":3218},"10.1146\u002Fannurev.bi.61.070192.003553",{"doi":3217},{"id":20,"text":3220,"url":20,"identifiers":3221},"10.1073\u002Fpnas.77.4.1783",{"doi":3220},{"id":20,"text":3223,"url":20,"identifiers":3224},"Hershko A, 1981, J. Biol. Chem., 256, 1525, 10.1016\u002FS0021-9258(19)69833-9",{"doi":3225},"10.1016\u002FS0021-9258(19)69833-9",{"id":20,"text":3227,"url":20,"identifiers":3228},"10.1016\u002F0006-291X(85)91050-2",{"doi":3227},{"id":20,"text":3230,"url":20,"identifiers":3231},"Hershko A, 1982, J. Biol. Chem., 258, 8206, 10.1016\u002FS0021-9258(20)82050-X",{"doi":3232},"10.1016\u002FS0021-9258(20)82050-X",{"id":20,"text":3234,"url":20,"identifiers":3235},"10.1073\u002Fpnas.81.6.1619",{"doi":3234},{"id":20,"text":3237,"url":20,"identifiers":3238},"10.1096\u002Ffasebj.11.14.9409540",{"doi":3237},{"id":20,"text":3240,"url":20,"identifiers":3241},"10.1126\u002Fscience.273.5282.1725",{"doi":3240},{"id":20,"text":3243,"url":20,"identifiers":3244},"10.1146\u002Fannurev.genet.30.1.405",{"doi":3243},{"id":20,"text":3246,"url":20,"identifiers":3247},"10.1016\u002FS0968-0004(98)01217-1",{"doi":3246},{"id":20,"text":3249,"url":20,"identifiers":3250},"Hough R, 1986, J. Biol. Chem., 262, 8303, 10.1016\u002FS0021-9258(18)47564-3",{"doi":3251},"10.1016\u002FS0021-9258(18)47564-3",{"id":20,"text":3253,"url":20,"identifiers":3254},"Hough R, 1986, J. Biol. Chem., 261, 2400, 10.1016\u002FS0021-9258(17)35950-1",{"doi":3255},"10.1016\u002FS0021-9258(17)35950-1",{"id":20,"text":3257,"url":20,"identifiers":3258},"10.1074\u002Fjbc.272.34.21364",{"doi":3257},{"id":20,"text":3260,"url":20,"identifiers":3261},"10.1074\u002Fjbc.270.19.11623",{"doi":3260},{"id":20,"text":3263,"url":20,"identifiers":3264},"10.1128\u002Fjb.179.23.7219-7225.1997",{"doi":3263},{"id":20,"text":3266,"url":20,"identifiers":3267},"10.1016\u002FS0014-5793(96)01261-6",{"doi":3266},{"id":20,"text":3269,"url":20,"identifiers":3270},"10.1016\u002FS0014-5793(97)01024-7",{"doi":3269},{"id":20,"text":3272,"url":20,"identifiers":3273},"10.1126\u002Fscience.274.5293.1652",{"doi":3272},{"id":20,"text":3275,"url":20,"identifiers":3276},"10.1074\u002Fjbc.273.4.1982",{"doi":3275},{"id":20,"text":3278,"url":20,"identifiers":3279},"10.1038\u002F37052",{"doi":3278},{"id":20,"text":3281,"url":20,"identifiers":3282},"10.1038\u002F37670",{"doi":3281},{"id":20,"text":3284,"url":20,"identifiers":3285},"10.1016\u002FS0952-7915(97)80163-X",{"doi":3284},{"id":20,"text":3287,"url":20,"identifiers":3288},"10.1038\u002F36786",{"doi":3287},{"id":20,"text":3290,"url":20,"identifiers":3291},"10.1074\u002Fjbc.272.45.28438",{"doi":3290},{"id":20,"text":3293,"url":20,"identifiers":3294},"10.1038\u002F385737a0",{"doi":3293},{"id":20,"text":3296,"url":20,"identifiers":3297},"10.1021\u002Fbi00163a001",{"doi":3296},{"id":20,"text":3299,"url":20,"identifiers":3300},"10.1126\u002Fscience.7725097",{"doi":3299},{"id":20,"text":3302,"url":20,"identifiers":3303},"10.1016\u002FS0968-0004(97)01058-X",{"doi":3302},{"id":20,"text":3305,"url":20,"identifiers":3306},"Mäntsälä P, 1984, J. Biol. Chem., 259, 14230, 10.1016\u002FS0021-9258(18)89882-9",{"doi":3307},"10.1016\u002FS0021-9258(18)89882-9",{"id":20,"text":3309,"url":20,"identifiers":3310},"10.1073\u002Fpnas.86.8.2597",{"doi":3309},{"id":20,"text":3312,"url":20,"identifiers":3313},"10.1038\u002F363552a0",{"doi":3312},{"id":20,"text":3315,"url":20,"identifiers":3316},"10.1002\u002Fj.1460-2075.1996.tb01082.x",{"doi":3315},{"id":20,"text":3318,"url":20,"identifiers":3319},"10.1056\u002FNEJM199612193352507",{"doi":3318},{"id":20,"text":3321,"url":20,"identifiers":3322},"10.1038\u002F360174a0",{"doi":3321},{"id":20,"text":3324,"url":20,"identifiers":3325},"10.1073\u002Fpnas.83.20.7588",{"doi":3324},{"id":20,"text":3327,"url":20,"identifiers":3328},"10.1038\u002F360597a0",{"doi":3327},{"id":20,"text":3330,"url":20,"identifiers":3331},"10.1093\u002Femboj\u002F16.17.5363",{"doi":3330},{"id":20,"text":3333,"url":20,"identifiers":3334},"10.1126\u002Fscience.2194290",{"doi":3333},{"id":20,"text":3336,"url":20,"identifiers":3337},"10.1073\u002Fpnas.95.21.12504",{"doi":3336},{"id":20,"text":3339,"url":20,"identifiers":3340},"10.1038\u002Fnsb1295-1102",{"doi":3339},{"id":20,"text":3342,"url":20,"identifiers":3343},"10.1021\u002Fbi00057a022",{"doi":3342},{"id":20,"text":3345,"url":20,"identifiers":3346},"10.1016\u002FS0968-0004(96)10065-7",{"doi":3345},{"id":20,"text":3348,"url":20,"identifiers":3349},"10.1096\u002Ffasebj.11.13.9367342",{"doi":3348},{"id":20,"text":3351,"url":20,"identifiers":3352},"10.1111\u002Fj.1432-1033.1994.00511.x",{"doi":3351},{"id":20,"text":3354,"url":20,"identifiers":3355},"10.1016\u002FS0962-8924(97)01212-9",{"doi":3354},{"id":20,"text":3357,"url":20,"identifiers":3358},"10.1006\u002Fjmbi.1993.1646",{"doi":3357},{"id":20,"text":3360,"url":20,"identifiers":3361},"Peters J-M, 1994, J. Biol. Chem., 269, 7709, 10.1016\u002FS0021-9258(17)37345-3",{"doi":3362},"10.1016\u002FS0021-9258(17)37345-3",{"id":20,"text":3364,"url":20,"identifiers":3365},"Peters J-M, 1991, Eur. J. Cell Biol., 56, 422",{},{"id":20,"text":3367,"url":20,"identifiers":3368},"10.1074\u002Fjbc.270.37.22023",{"doi":3367},{"id":20,"text":3370,"url":20,"identifiers":3371},"10.1016\u002FS0092-8674(00)80942-3",{"doi":3370},{"id":20,"text":3373,"url":20,"identifiers":3374},"Realini C, 1994, J. Biol. Chem., 269, 20727, 10.1016\u002FS0021-9258(17)32052-5",{"doi":3375},"10.1016\u002FS0021-9258(17)32052-5",{"id":20,"text":3377,"url":20,"identifiers":3378},"10.1074\u002Fjbc.272.20.13403",{"doi":3377},{"id":20,"text":3380,"url":20,"identifiers":3381},"10.1016\u002FS0952-7915(98)80040-X",{"doi":3380},{"id":20,"text":3383,"url":20,"identifiers":3384},"10.1016\u002FS0092-8674(94)90462-6",{"doi":3383},{"id":20,"text":3386,"url":20,"identifiers":3387},"10.1073\u002Fpnas.93.12.5808",{"doi":3386},{"id":20,"text":3389,"url":20,"identifiers":3390},"10.1038\u002Fnsb0297-133",{"doi":3389},{"id":20,"text":3392,"url":20,"identifiers":3393},"Rose IA, 1997, J. Biol. Chem., 254, 8135, 10.1016\u002FS0021-9258(19)86865-5",{"doi":3394},"10.1016\u002FS0021-9258(19)86865-5",{"id":20,"text":3396,"url":20,"identifiers":3397},"10.1038\u002F379655a0",{"doi":3396},{"id":20,"text":3399,"url":20,"identifiers":3400},"10.1023\u002FA:1006844305067",{"doi":3399},{"id":20,"text":3402,"url":20,"identifiers":3403},"10.1016\u002FS0014-5793(98)00205-1",{"doi":3402},{"id":20,"text":3405,"url":20,"identifiers":3406},"10.1038\u002F373081a0",{"doi":3405},{"id":20,"text":3408,"url":20,"identifiers":3409},"10.1016\u002F0968-0004(96)10038-4",{"doi":3408},{"id":20,"text":3411,"url":20,"identifiers":3412},"10.1007\u002FBF00990969",{"doi":3411},{"id":20,"text":3414,"url":20,"identifiers":3415},"10.1002\u002Fj.1460-2075.1996.tb01081.x",{"doi":3414},{"id":20,"text":3417,"url":20,"identifiers":3418},"10.1126\u002Fscience.7725107",{"doi":3417},{"id":20,"text":3420,"url":20,"identifiers":3421},"10.1016\u002F0014-5793(95)00036-9",{"doi":3420},{"id":20,"text":3423,"url":20,"identifiers":3424},"10.1111\u002Fj.1432-1033.1997.01143.x",{"doi":3423},{"id":20,"text":3426,"url":20,"identifiers":3427},"10.1038\u002F357700a0",{"doi":3426},{"id":20,"text":3429,"url":20,"identifiers":3430},"10.1111\u002Fj.1432-1033.1990.tb19207.x",{"doi":3429},{"id":20,"text":3432,"url":20,"identifiers":3433},"10.1126\u002Fscience.8197456",{"doi":3432},{"id":20,"text":3435,"url":20,"identifiers":3436},"10.1038\u002F365176a0",{"doi":3435},{"id":20,"text":3438,"url":20,"identifiers":3439},"10.1096\u002Ffasebj.11.14.9409541",{"doi":3438},{"id":20,"text":3441,"url":20,"identifiers":3442},"10.1038\u002F357698a0",{"doi":3441},{"id":20,"text":3444,"url":20,"identifiers":3445},"10.1038\u002F374088a0",{"doi":3444},{"id":20,"text":3447,"url":20,"identifiers":3448},"10.1016\u002FS0960-9822(95)00153-9",{"doi":3447},{"id":20,"text":3450,"url":20,"identifiers":3451},"10.1016\u002F0014-5793(88)80306-5",{"doi":3450},{"id":20,"text":3453,"url":20,"identifiers":3454},"10.1002\u002Fj.1460-2075.1996.tb00658.x",{"doi":3453},{"id":20,"text":3456,"url":20,"identifiers":3457},"10.1126\u002Fscience.1962196",{"doi":3456},{"id":20,"text":3459,"url":20,"identifiers":3460},"10.1038\u002F41483",{"doi":3459},{"id":20,"text":3462,"url":20,"identifiers":3463},"10.1111\u002Fj.1432-1033.1996.0912u.x",{"doi":3462},{"id":20,"text":3465,"url":20,"identifiers":3466},"10.1016\u002F1074-7613(94)90043-4",{"doi":3465},{"id":20,"text":3468,"url":20,"identifiers":3469},"10.1073\u002Fpnas.93.2.856",{"doi":3468},{"id":20,"text":3471,"url":20,"identifiers":3472},"10.1128\u002FMCB.16.11.6020",{"doi":3471},{"id":20,"text":3474,"url":20,"identifiers":3475},"10.1016\u002FS0968-0004(97)01122-5",{"doi":3474},{"id":20,"text":3477,"url":20,"identifiers":3478},"10.1006\u002Fabbi.1995.0067",{"doi":3477},{"id":20,"text":3480,"url":20,"identifiers":3481},"10.1006\u002Fjsbi.1998.3958",{"doi":3480},{"id":20,"text":3483,"url":20,"identifiers":3484},"Waxman L, 1987, J. Biol. Chem., 262, 2451, 10.1016\u002FS0021-9258(18)61525-X",{"doi":3485},"10.1016\u002FS0021-9258(18)61525-X",{"id":20,"text":3487,"url":20,"identifiers":3488},"10.1038\u002Fnsb0395-199",{"doi":3487},{"id":20,"text":3490,"url":20,"identifiers":3491},"10.1016\u002F0014-5793(94)00665-2",{"doi":3490},{"id":20,"text":3493,"url":20,"identifiers":3494},"10.1023\u002FA:1006851428691",{"doi":3493},{"id":20,"text":3496,"url":20,"identifiers":3497},"10.1111\u002Fj.1471-4159.1980.tb07873.x",{"doi":3496},{"id":20,"text":3499,"url":20,"identifiers":3500},"10.1096\u002Ffasebj.11.14.9409543",{"doi":3499},{"id":20,"text":3502,"url":20,"identifiers":3503},"Wilkinson KD, 1980, J. Biol. Chem., 255, 7529, 10.1016\u002FS0021-9258(19)43857-X",{"doi":3504},"10.1016\u002FS0021-9258(19)43857-X",{"id":20,"text":3506,"url":20,"identifiers":3507},"10.1016\u002F0014-5793(93)81757-Q",{"doi":3506},{"id":20,"text":3509,"url":20,"identifiers":3510},"Wu RS, 1981, J. Biol. Chem., 256, 5916, 10.1016\u002FS0021-9258(19)69296-3",{"doi":3511},"10.1016\u002FS0021-9258(19)69296-3",{"id":20,"text":3513,"url":20,"identifiers":3514},"10.1074\u002Fjbc.270.46.27687",{"doi":3513},{"id":20,"text":3516,"url":20,"identifiers":3517},"10.1091\u002Fmbc.7.6.853",{"doi":3516},{"id":20,"text":3519,"url":20,"identifiers":3520},"10.1074\u002Fjbc.271.24.14035",{"doi":3519},{"id":20,"text":3522,"url":20,"identifiers":3523},"10.1016\u002FS0014-5793(97)00742-4",{"doi":3522},{"id":20,"text":3525,"url":20,"identifiers":3526},"10.1146\u002Fannurev.immunol.14.1.369",{"doi":3525},{"id":20,"text":3528,"url":20,"identifiers":3529},"10.1073\u002Fpnas.95.6.2807",{"doi":3528},{"id":20,"text":3531,"url":20,"identifiers":3532},"Zhou G, 1992, J. Biol. Chem., 267, 7936, 10.1016\u002FS0021-9258(18)42602-6",{"doi":3533},"10.1016\u002FS0021-9258(18)42602-6",{"id":20,"text":3535,"url":20,"identifiers":3536},"10.1038\u002Fnsb1194-765",{"doi":3535},{"id":3538,"createTime":3539,"updateTime":3539,"relativeEntities":3540,"slug":3541,"properties":3542,"entityType":48,"verifyStatus":49,"verifyTime":3539,"verifyNote":50,"syncStatus":19,"languages":3555,"translateLanguages":20,"viewCount":21,"primaryUrl":3556,"fullTextUrl":20,"authors":3557,"publicationType":95,"publisherRelationship":3600,"citationCount":3616,"citationInfo":3617,"publishDate":3620,"publishYear":3621,"citationAnalyzeStatus":19,"lastCitationAnalyze":20,"indexDatabases":20,"openAccess":20,"references":3622,"isForceReanalyzing":360},"a3f079d8-0b8c-4a4a-9de5-a5b5e5b36ff8","2024-09-30T18:32:56.196+00:00",[],"Gating-Spring-Models-of-Mechanoelectrical-Transduction-by-Hair-Cells-of-the-Internal-Ear",{"mag":3543,"keywords":3545,"openalex":3546,"abstract":3548,"title":3549,"pm":3551,"doi":3553},{"VOID":3544},"1894521878",{},{"VOID":3547},"W1894521878",{},{"EN":3550},"Gating-Spring Models of Mechanoelectrical Transduction by Hair Cells of the Internal Ear",{"VOID":3552},"7663129",{"VOID":3554},"10.1146\u002Fannurev.bb.24.060195.000423",[52],"https:\u002F\u002Fwww.annualreviews.org\u002Fdoi\u002F10.1146\u002Fannurev.bb.24.060195.000423",[3558,3578],{"id":3559,"sortIndex":21,"researcher":20,"roles":3560,"affiliations":3561,"properties":3573},"9383a90c-9512-4a63-97c9-c7a5e5bcb648",[],[3562],{"id":3563,"sortIndex":21,"affiliation":3564,"properties":20},"01132287-0bd9-4e47-8ae4-53de6cac7485",{"id":3565,"createTime":3566,"updateTime":3567,"relativeEntities":3568,"slug":3569,"properties":3570,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"13d59224-45ed-4c99-a9e7-b55e5b642430","2024-09-21T07:11:19.960+00:00","2024-10-15T00:28:38.597+00:00",[],"Neurology-Neurotherapeutics",{"title":3571},{"EN":3572},"Neurology & Neurotherapeutics",{"openalex":3574,"title":3576},{"VOID":3575},"A5089743882",{"EN":3577},"Vladislav S. Markin",{"id":3579,"sortIndex":57,"researcher":20,"roles":3580,"affiliations":3581,"properties":3593},"ae25a692-3d40-4a76-a250-15dafcb018c4",[],[3582],{"id":3583,"sortIndex":21,"affiliation":3584,"properties":20},"dfbe0a0f-13c1-435b-8d1a-e329b3c338a6",{"id":3585,"createTime":3586,"updateTime":3587,"relativeEntities":3588,"slug":3589,"properties":3590,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"aeb5796d-60cb-409f-b9eb-ded730287253","2024-01-16T18:45:55.469+00:00","2025-02-11T05:15:03.402+00:00",[],"University-of-Texas-Southwestern-Medical-Center",{"title":3591},{"VI":3592},"University of Texas Southwestern Medical Center",{"openalex":3594,"orcid":3596,"title":3598},{"VOID":3595},"A5057549975",{"VOID":3597},"https:\u002F\u002Forcid.org\u002F0000-0002-0295-1323",{"EN":3599},"A. J. Hudspeth",{"url":20,"publisher":3601,"properties":3610},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":3602,"slug":10,"properties":3603,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":3607,"manageAffiliations":3608,"indexDatabases":3609,"url":20,"thumbnailPath":20,"statistic":20,"gsStatistic":20,"type":20,"analyzePriority":20},[],{"issn":3604,"eissn":3605,"title":3606},{"VOID":13},{"VOID":15},{"EN":17},[],[],[],{"volume":3611,"pages":3613,"issue":3615},{"VOID":3612},"24",{"VOID":3614},"59-83",{"VOID":112},151,{"total":3616,"publishYear":20,"statisticByYear":3618},{"2012":2506,"2013":2429,"2014":122,"2015":124,"2016":3619,"2017":122,"2018":3619,"2019":3619,"2020":3619,"2021":2506,"2022":521,"2023":2506,"2024":2506},5,"1995-06-01",1995,[],{"id":3624,"createTime":3625,"updateTime":3625,"relativeEntities":3626,"slug":3627,"properties":3628,"entityType":48,"verifyStatus":49,"verifyTime":3625,"verifyNote":50,"syncStatus":19,"languages":3642,"translateLanguages":20,"viewCount":21,"primaryUrl":3643,"fullTextUrl":20,"authors":3644,"publicationType":95,"publisherRelationship":3681,"citationCount":3696,"citationInfo":3697,"publishDate":1649,"publishYear":1650,"citationAnalyzeStatus":19,"lastCitationAnalyze":20,"indexDatabases":20,"openAccess":20,"references":3703,"isForceReanalyzing":360},"8e42f32b-c861-415d-93b0-457d0e7d3207","2024-10-04T18:07:31.026+00:00",[],"HIERARCHY-AND-DYNAMICS-OF-RNA-FOLDING",{"mag":3629,"keywords":3631,"openalex":3632,"abstract":3634,"title":3636,"pm":3638,"doi":3640},{"VOID":3630},"2111652614",{},{"VOID":3633},"W2111652614",{"EN":3635},"\u003Cjats:p>▪ Abstract  The evidence showing that the self-assembly of complex RNAs occurs in discrete transitions, each relating to the folding of sub-systems of increasing size and complexity starting from a state with most of the secondary structure, is reviewed. The reciprocal influence of the concentration of magnesium ions and nucleotide mutations on tertiary structure is analyzed. Several observations demonstrate that detrimental mutations can be rescued by high magnesium concentrations, while stabilizing mutations lead to a lesser dependence on magnesium ion concentration. Recent data point to the central controlling and monitoring roles of RNA-binding proteins that can bind to the different folding stages, either before full establishment of the secondary structure or at the molten globule state before the cooperative transition to the final three-dimensional structure.\u003C\u002Fjats:p>",{"EN":3637},"HIERARCHY AND DYNAMICS OF RNA FOLDING",{"VOID":3639},"9241415",{"VOID":3641},"10.1146\u002Fannurev.biophys.26.1.113",[52],"https:\u002F\u002Fwww.annualreviews.org\u002Fdoi\u002F10.1146\u002Fannurev.biophys.26.1.113",[3645,3666],{"id":3646,"sortIndex":57,"researcher":20,"roles":3647,"affiliations":3648,"properties":3659},"8a552e7c-7f07-4285-9db8-5775fd8e9ea2",[],[3649],{"id":3650,"sortIndex":21,"affiliation":3651,"properties":20},"531b0690-0279-4e60-98f9-ead8a6ef5dd2",{"id":3652,"createTime":3653,"updateTime":3653,"relativeEntities":3654,"slug":3655,"properties":3656,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"86dd6fff-3f8e-4741-abda-9e911914a3be","2024-10-04T18:07:31.034+00:00",[],"Institut-de-Biologie-Mol%C3%A9culaire-et-Cellulaire-Centre-National-de-la-Recherche-Scientifique-UPR-9002-15-rue-Descartes-Strasbourg-67084-France-",{"title":3657},{"EN":3658},"Institut de Biologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique, UPR 9002 15 rue Descartes, Strasbourg, 67084 France;",{"openalex":3660,"orcid":3662,"title":3664},{"VOID":3661},"A5018416560",{"VOID":3663},"https:\u002F\u002Forcid.org\u002F0000-0002-6172-5422",{"EN":3665},"Éric Westhof",{"id":3667,"sortIndex":21,"researcher":20,"roles":3668,"affiliations":3669,"properties":3676},"c5de0f4c-2900-44b7-b6eb-2eddcedb0c9e",[],[3670],{"id":3671,"sortIndex":21,"affiliation":3672,"properties":20},"2bd948a7-3e5f-44e5-8a3c-663279a6542c",{"id":3652,"createTime":3653,"updateTime":3653,"relativeEntities":3673,"slug":3655,"properties":3674,"entityType":70,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},[],{"title":3675},{"EN":3658},{"openalex":3677,"title":3679},{"VOID":3678},"A5071882977",{"EN":3680},"Philippe Brion",{"url":20,"publisher":3682,"properties":3691},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":3683,"slug":10,"properties":3684,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":3688,"manageAffiliations":3689,"indexDatabases":3690,"url":20,"thumbnailPath":20,"statistic":20,"gsStatistic":20,"type":20,"analyzePriority":20},[],{"issn":3685,"eissn":3686,"title":3687},{"VOID":13},{"VOID":15},{"EN":17},[],[],[],{"volume":3692,"pages":3693,"issue":3695},{"VOID":1632},{"VOID":3694},"113-137",{"VOID":112},551,{"total":3696,"publishYear":20,"statisticByYear":3698},{"2012":3699,"2013":3700,"2014":3701,"2015":1053,"2016":3700,"2017":518,"2018":3702,"2019":118,"2020":123,"2021":1052,"2022":123,"2023":3700,"2024":122},27,21,24,23,[3704,3707,3710,3713,3715,3718,3721,3724,3727,3730,3733,3736,3739,3742,3745,3749,3752,3755,3758,3761,3764,3767,3770,3773,3776,3779,3782,3785,3788,3791,3794,3797,3801,3804,3807,3810,3813,3816,3819,3822,3825,3828,3831,3834,3837,3840,3843,3846,3849,3852,3855,3858,3861,3864,3867,3870,3873,3876,3879,3882,3885,3888,3891,3894,3897,3901,3904,3907,3910,3913,3916,3919,3922,3925,3928,3931,3934,3937,3940,3943,3946,3949,3952,3955,3958,3961,3964,3967,3970,3973,3976,3979,3982,3985,3988,3991,3994,3997,4000,4003,4006,4009,4012,4015,4018,4021,4024,4027,4030,4033,4037,4040,4043,4046,4049,4052,4055,4058,4061,4064,4067],{"id":20,"text":3705,"url":20,"identifiers":3706},"10.1093\u002Fnar\u002F19.21.5901",{"doi":3705},{"id":20,"text":3708,"url":20,"identifiers":3709},"10.1093\u002Fnar\u002F20.4.819",{"doi":3708},{"id":20,"text":3711,"url":20,"identifiers":3712},"10.1016\u002FS0968-0004(00)89039-8",{"doi":3711},{"id":20,"text":1797,"url":20,"identifiers":3714},{},{"id":20,"text":3716,"url":20,"identifiers":3717},"10.1021\u002Fbi00052a021",{"doi":3716},{"id":20,"text":3719,"url":20,"identifiers":3720},"10.1021\u002Fbi00019a031",{"doi":3719},{"id":20,"text":3722,"url":20,"identifiers":3723},"10.1021\u002Fbi00479a027",{"doi":3722},{"id":20,"text":3725,"url":20,"identifiers":3726},"10.1021\u002Fbi960870m",{"doi":3725},{"id":20,"text":3728,"url":20,"identifiers":3729},"10.1021\u002Fbi00273a005",{"doi":3728},{"id":20,"text":3731,"url":20,"identifiers":3732},"10.1016\u002F0022-2836(80)90051-0",{"doi":3731},{"id":20,"text":3734,"url":20,"identifiers":3735},"10.1021\u002Fbi00279a014",{"doi":3734},{"id":20,"text":3737,"url":20,"identifiers":3738},"10.1007\u002F978-3-642-78666-2_5",{"doi":3737},{"id":20,"text":3740,"url":20,"identifiers":3741},"10.1016\u002FS0092-8674(00)81807-3",{"doi":3740},{"id":20,"text":3743,"url":20,"identifiers":3744},"10.1006\u002Fjmbi.1996.0182",{"doi":3743},{"id":20,"text":3746,"url":20,"identifiers":3747},"Cech TR, Herschlag D. 1996.Group I ribozymes: substrate recognition, catalytic strategies, and comparative mechanistic analysis.InNucleic Acids and Molecular Biology, ed. F Eckstein, DMJ Lilley, 10:1–17. Berlin: Springer-Verlag",{"doi":3748},"10.1007\u002F978-3-642-61202-2_1",{"id":20,"text":3750,"url":20,"identifiers":3751},"10.1126\u002Fscience.1989074",{"doi":3750},{"id":20,"text":3753,"url":20,"identifiers":3754},"10.1101\u002Fgad.8.13.1575",{"doi":3753},{"id":20,"text":3756,"url":20,"identifiers":3757},"10.1021\u002Fbi00773a024",{"doi":3756},{"id":20,"text":3759,"url":20,"identifiers":3760},"10.1002\u002Fj.1460-2075.1995.tb07111.x",{"doi":3759},{"id":20,"text":3762,"url":20,"identifiers":3763},"10.1021\u002Fbi00716a019",{"doi":3762},{"id":20,"text":3765,"url":20,"identifiers":3766},"10.1016\u002F0022-2836(74)90560-9",{"doi":3765},{"id":20,"text":3768,"url":20,"identifiers":3769},"Doudna JA, 1995, RNA, 1, 36",{},{"id":20,"text":3771,"url":20,"identifiers":3772},"10.1038\u002Fnsb0596-397",{"doi":3771},{"id":20,"text":3774,"url":20,"identifiers":3775},"10.1016\u002F0092-8674(95)90218-X",{"doi":3774},{"id":20,"text":3777,"url":20,"identifiers":3778},"10.1021\u002Fbi00213a040",{"doi":3777},{"id":20,"text":3780,"url":20,"identifiers":3781},"10.1073\u002Fpnas.91.21.9675",{"doi":3780},{"id":20,"text":3783,"url":20,"identifiers":3784},"10.1038\u002Fnsb0195-10a",{"doi":3783},{"id":20,"text":3786,"url":20,"identifiers":3787},"10.1021\u002Fbi00203a029",{"doi":3786},{"id":20,"text":3789,"url":20,"identifiers":3790},"10.1101\u002FSQB.1966.031.01.068",{"doi":3789},{"id":20,"text":3792,"url":20,"identifiers":3793},"10.1101\u002Fgad.5.10.1870",{"doi":3792},{"id":20,"text":3795,"url":20,"identifiers":3796},"10.1006\u002Fjmbi.1994.1493",{"doi":3795},{"id":20,"text":3798,"url":20,"identifiers":3799},"Gopalan V, Talbot SJ, Altman S. 1994.RNA-protein interactions in RNAse P.InRNA-Protein Interactions, ed. K Nagai, IW Mattaj, pp. 103–26. Oxford: IRL Press, Oxford Univ. Press",{"doi":3800},"10.1093\u002Foso\u002F9780199635054.003.0005",{"id":20,"text":3802,"url":20,"identifiers":3803},"10.1006\u002Fjmbi.1995.0275",{"doi":3802},{"id":20,"text":3805,"url":20,"identifiers":3806},"Groeneveld H, 1995, RNA, 1, 79",{},{"id":20,"text":3808,"url":20,"identifiers":3809},"10.1016\u002FS0006-3495(82)84553-0",{"doi":3808},{"id":20,"text":3811,"url":20,"identifiers":3812},"10.1006\u002Fjmbi.1995.0356",{"doi":3811},{"id":20,"text":3814,"url":20,"identifiers":3815},"10.1101\u002Fgad.6.8.1357",{"doi":3814},{"id":20,"text":3817,"url":20,"identifiers":3818},"10.1002\u002Fbip.1977.360160714",{"doi":3817},{"id":20,"text":3820,"url":20,"identifiers":3821},"10.1074\u002Fjbc.270.36.20871",{"doi":3820},{"id":20,"text":3823,"url":20,"identifiers":3824},"10.1002\u002Fj.1460-2075.1994.tb06586.x",{"doi":3823},{"id":20,"text":3826,"url":20,"identifiers":3827},"10.1039\u002Fft9959102531",{"doi":3826},{"id":20,"text":3829,"url":20,"identifiers":3830},"10.1021\u002Fbi00654a013",{"doi":3829},{"id":20,"text":3832,"url":20,"identifiers":3833},"10.1016\u002F0022-2836(90)90275-Q",{"doi":3832},{"id":20,"text":3835,"url":20,"identifiers":3836},"10.1016\u002F0022-2836(92)90557-Z",{"doi":3835},{"id":20,"text":3838,"url":20,"identifiers":3839},"10.1016\u002F0076-6879(90)83019-6",{"doi":3838},{"id":20,"text":3841,"url":20,"identifiers":3842},"10.1016\u002F0022-2836(94)90055-8",{"doi":3841},{"id":20,"text":3844,"url":20,"identifiers":3845},"10.1007\u002F978-3-642-61202-2_3",{"doi":3844},{"id":20,"text":3847,"url":20,"identifiers":3848},"10.1016\u002F0022-2836(91)90925-V",{"doi":3847},{"id":20,"text":3850,"url":20,"identifiers":3851},"10.1006\u002Fjmbi.1993.1590",{"doi":3850},{"id":20,"text":3853,"url":20,"identifiers":3854},"10.1093\u002Fnar\u002F17.19.7879",{"doi":3853},{"id":20,"text":3856,"url":20,"identifiers":3857},"10.1002\u002Fprot.340060202",{"doi":3856},{"id":20,"text":3859,"url":20,"identifiers":3860},"10.1093\u002Fnar\u002F9.19.5109",{"doi":3859},{"id":20,"text":3862,"url":20,"identifiers":3863},"10.1093\u002Fnar\u002F18.13.3803",{"doi":3862},{"id":20,"text":3865,"url":20,"identifiers":3866},"10.1002\u002Fj.1460-2075.1994.tb06557.x",{"doi":3865},{"id":20,"text":3868,"url":20,"identifiers":3869},"10.1006\u002Fjmbi.1994.1255",{"doi":3868},{"id":20,"text":3871,"url":20,"identifiers":3872},"10.1006\u002Fjmbi.1994.1256",{"doi":3871},{"id":20,"text":3874,"url":20,"identifiers":3875},"10.1016\u002F0968-0004(90)90283-H",{"doi":3874},{"id":20,"text":3877,"url":20,"identifiers":3878},"LeCuyer KA, 1993, Trends Biochem. Sci., 32, 5301",{},{"id":20,"text":3880,"url":20,"identifiers":3881},"10.1073\u002Fpnas.91.8.3373",{"doi":3880},{"id":20,"text":3883,"url":20,"identifiers":3884},"Levinthal C, 1968, J. Chem. Phys., 65, 44",{},{"id":20,"text":3886,"url":20,"identifiers":3887},"10.1016\u002FS0959-440X(96)80046-7",{"doi":3886},{"id":20,"text":3889,"url":20,"identifiers":3890},"10.1006\u002Fjmbi.1994.1753",{"doi":3889},{"id":20,"text":3892,"url":20,"identifiers":3893},"10.1111\u002Fj.1365-2958.1994.tb01337.x",{"doi":3892},{"id":20,"text":3895,"url":20,"identifiers":3896},"10.1126\u002Fscience.7539549",{"doi":3895},{"id":20,"text":3898,"url":20,"identifiers":3899},"McGraw P, 1983, J. Biol. Chem., 258, 9459, 10.1016\u002FS0021-9258(17)44690-4",{"doi":3900},"10.1016\u002FS0021-9258(17)44690-4",{"id":20,"text":3902,"url":20,"identifiers":3903},"10.1038\u002F347578a0",{"doi":3902},{"id":20,"text":3905,"url":20,"identifiers":3906},"10.1101\u002Fgad.6.8.1373",{"doi":3905},{"id":20,"text":3908,"url":20,"identifiers":3909},"10.1016\u002F0022-2836(90)90386-Z",{"doi":3908},{"id":20,"text":3911,"url":20,"identifiers":3912},"10.1038\u002F370147a0",{"doi":3911},{"id":20,"text":3914,"url":20,"identifiers":3915},"10.1016\u002F0092-8674(92)90449-M",{"doi":3914},{"id":20,"text":3917,"url":20,"identifiers":3918},"10.1093\u002Fnar\u002F23.15.3056",{"doi":3917},{"id":20,"text":3920,"url":20,"identifiers":3921},"10.1021\u002Fbi00071a003",{"doi":3920},{"id":20,"text":3923,"url":20,"identifiers":3924},"10.1006\u002Fjmbi.1994.1117",{"doi":3923},{"id":20,"text":3926,"url":20,"identifiers":3927},"10.1126\u002Fscience.8085157",{"doi":3926},{"id":20,"text":3929,"url":20,"identifiers":3930},"10.1006\u002Fjmbi.1996.0391",{"doi":3929},{"id":20,"text":3932,"url":20,"identifiers":3933},"10.1021\u002Fbi00003a024",{"doi":3932},{"id":20,"text":3935,"url":20,"identifiers":3936},"Pan T, Long DM, Uhlenbeck OC. 1993.Divalent metal ions in RNA folding and catalysis.InRNA World, ed. RF Gesteland, JF Atkins, pp. 271–302. Cold Spring Harbor, NY: Cold Spring Harbor Lab. Press",{},{"id":20,"text":3938,"url":20,"identifiers":3939},"10.1038\u002F372068a0",{"doi":3938},{"id":20,"text":3941,"url":20,"identifiers":3942},"10.1038\u002F372111a0",{"doi":3941},{"id":20,"text":3944,"url":20,"identifiers":3945},"10.1007\u002F978-3-642-81117-3_5",{"doi":3944},{"id":20,"text":3947,"url":20,"identifiers":3948},"10.1016\u002F0022-2836(78)90421-7",{"doi":3947},{"id":20,"text":3950,"url":20,"identifiers":3951},"10.1016\u002FS0968-0004(00)89081-7",{"doi":3950},{"id":20,"text":3953,"url":20,"identifiers":3954},"10.1021\u002Fbi00175a047",{"doi":3953},{"id":20,"text":3956,"url":20,"identifiers":3957},"10.1021\u002Fbi9527348",{"doi":3956},{"id":20,"text":3959,"url":20,"identifiers":3960},"10.1016\u002F0022-2836(73)90388-4",{"doi":3959},{"id":20,"text":3962,"url":20,"identifiers":3963},"10.1002\u002Fj.1460-2075.1996.tb00642.x",{"doi":3962},{"id":20,"text":3965,"url":20,"identifiers":3966},"10.1111\u002Fj.1432-1033.1977.tb11930.x",{"doi":3965},{"id":20,"text":3968,"url":20,"identifiers":3969},"10.1126\u002Fscience.1373521",{"doi":3968},{"id":20,"text":3971,"url":20,"identifiers":3972},"10.1016\u002FS0092-8674(05)80004-2",{"doi":3971},{"id":20,"text":3974,"url":20,"identifiers":3975},"10.1016\u002F0076-6879(95)59047-1",{"doi":3974},{"id":20,"text":3977,"url":20,"identifiers":3978},"10.1074\u002Fjbc.270.37.21552",{"doi":3977},{"id":20,"text":3980,"url":20,"identifiers":3981},"10.1093\u002Fnar\u002F17.14.5665",{"doi":3980},{"id":20,"text":3983,"url":20,"identifiers":3984},"10.1096\u002Ffasebj.9.11.7544309",{"doi":3983},{"id":20,"text":3986,"url":20,"identifiers":3987},"10.1021\u002Fbi00646a024",{"doi":3986},{"id":20,"text":3989,"url":20,"identifiers":3990},"10.1021\u002Fbi00646a025",{"doi":3989},{"id":20,"text":3992,"url":20,"identifiers":3993},"Tanner MA, 1996, RNA, 2, 74",{},{"id":20,"text":3995,"url":20,"identifiers":3996},"10.1016\u002FS0960-9822(00)00109-3",{"doi":3995},{"id":20,"text":3998,"url":20,"identifiers":3999},"10.1021\u002Far9500933",{"doi":3998},{"id":20,"text":4001,"url":20,"identifiers":4002},"10.1007\u002F978-3-642-61202-2_10",{"doi":4001},{"id":20,"text":4004,"url":20,"identifiers":4005},"10.1073\u002Fpnas.85.5.1364",{"doi":4004},{"id":20,"text":4007,"url":20,"identifiers":4008},"10.1146\u002Fannurev.bb.17.060188.001123",{"doi":4007},{"id":20,"text":4010,"url":20,"identifiers":4011},"Uhlenbeck OC, 1995, RNA, 1, 4",{},{"id":20,"text":4013,"url":20,"identifiers":4014},"10.1073\u002Fpnas.88.1.184",{"doi":4013},{"id":20,"text":4016,"url":20,"identifiers":4017},"10.1002\u002Fj.1460-2075.1993.tb06163.x",{"doi":4016},{"id":20,"text":4019,"url":20,"identifiers":4020},"10.1021\u002Fbi00498a022",{"doi":4019},{"id":20,"text":4022,"url":20,"identifiers":4023},"10.1021\u002Fbi00023a020",{"doi":4022},{"id":20,"text":4025,"url":20,"identifiers":4026},"10.1016\u002F0092-8674(95)90309-7",{"doi":4025},{"id":20,"text":4028,"url":20,"identifiers":4029},"10.1126\u002Fscience.271.5247.345",{"doi":4028},{"id":20,"text":4031,"url":20,"identifiers":4032},"10.1016\u002F0959-440X(92)90221-R",{"doi":4031},{"id":20,"text":4034,"url":20,"identifiers":4035},"Westhof E, Michel F. 1994.Prediction and experimental investigation of RNA secondary and tertiary foldings.InRNA-Protein Interactions, ed. K Nagai, IW Mattaj, pp. 25–51. Oxford: IRL Press, Oxford Univ. Press",{"doi":4036},"10.1093\u002Foso\u002F9780199635054.003.0002",{"id":20,"text":4038,"url":20,"identifiers":4039},"10.1016\u002F0022-2836(85)90048-8",{"doi":4038},{"id":20,"text":4041,"url":20,"identifiers":4042},"10.1073\u002Fpnas.87.21.8467",{"doi":4041},{"id":20,"text":4044,"url":20,"identifiers":4045},"10.1126\u002Fscience.7886447",{"doi":4044},{"id":20,"text":4047,"url":20,"identifiers":4048},"10.1021\u002Fbi00222a006",{"doi":4047},{"id":20,"text":4050,"url":20,"identifiers":4051},"10.1128\u002FMCB.13.2.1137",{"doi":4050},{"id":20,"text":4053,"url":20,"identifiers":4054},"10.1016\u002F0022-2836(90)90193-P",{"doi":4053},{"id":20,"text":4056,"url":20,"identifiers":4057},"Wyatt JR, Tinoco IJr . 1993.RNA structural elements.InRNA World, ed. RF Gesteland, JF Atkins, pp. 465–97. Cold Spring Harbor, NY: Cold Spring Harbor Lab. Press",{},{"id":20,"text":4059,"url":20,"identifiers":4060},"10.1126\u002Fscience.8052848",{"doi":4059},{"id":20,"text":4062,"url":20,"identifiers":4063},"10.1093\u002Fnar\u002F24.5.854",{"doi":4062},{"id":20,"text":4065,"url":20,"identifiers":4066},"10.1038\u002Fnsb0596-432",{"doi":4065},{"id":20,"text":4068,"url":20,"identifiers":4069},"Zhang A, 1995, RNA, 1, 783",{}]