[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"_public_publisher_byId_781fea9e-1fb1-4632-819d-b459e39a7f41":3,"_public_publication_all{\"sortAscending\":false,\"sortField\":\"updateTime\",\"page\":0,\"size\":10,\"facet\":true,\"searchKey\":\"publisherId:781fea9e-1fb1-4632-819d-b459e39a7f41,\"}":62},{"code":4,"data":5,"meta":18},"SUCCESS",{"id":6,"createTime":7,"updateTime":8,"relativeEntities":9,"slug":10,"properties":11,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":20,"manageAffiliations":27,"indexDatabases":35,"url":53,"thumbnailPath":18,"statistic":54,"gsStatistic":18,"type":61,"analyzePriority":18},"781fea9e-1fb1-4632-819d-b459e39a7f41","2024-04-11T07:26:12.241+00:00","2025-01-14T07:34:43.081+00:00",[],"Ain-Shams-Journal-of-Anesthesiology",{"issn":12,"title":14},{"VOID":13},"2090-925X",{"EN":15},"Ain-Shams Journal of Anesthesiology","PUBLISHER","PENDING",null,0,[21],{"id":22,"createTime":18,"updateTime":18,"relativeEntities":23,"label":24,"description":26,"parentId":18,"standard":18,"scholarHubFieldId":18},"10e0e407-a861-41ca-a20e-2bf3ffc44b93",[],{"EN":25},"Anesthesiology",{},[28],{"id":29,"createTime":18,"updateTime":18,"relativeEntities":30,"slug":18,"properties":31,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":34,"statistic":18},"26a19206-5cad-4456-bb2f-49abd254fbc6",[],{"title":32},{"EN":33},"SPRINGER",[],[36],{"id":37,"indexDatabase":38,"url":50,"indexYears":18,"academicFieldIds":51,"indexDatabaseRanking":18},"cb6cd6eb-1dcf-400e-8e46-82c771ca4a18",{"id":39,"createTime":18,"updateTime":18,"relativeEntities":40,"label":41,"description":43,"key":46,"publicationTags":47,"standard":18},"88bab0f7-443b-476c-a72a-7fa5222da393",[],{"EN":42,"VI":42},"ISI\u002FESCI  - Emerging Sources Citation Index",{"EN":44,"VI":45},"ESCI database","Cơ sở dữ liệu ESCI","esci",[48,49],"ESCI","ISI","https:\u002F\u002Fmjl.clarivate.com\u002Fsearch-results?issn=1687-7934",[52],"3863b6ce-7a2b-4e2a-b6a8-04302c7b4552","https:\u002F\u002Flink.springer.com\u002Fjournal\u002F42077",{"impactFactor":19,"impactFactorByYear":55,"i10Index":19,"i10IndexLast5Year":19,"totalPublication":56,"totalPublicationByYear":57,"totalCitation":19,"totalCitationByYear":59,"totalCitationPerPublication":19,"totalCitationPerPublicationByYear":60,"hindexLast5Year":19,"hindex":19},{},3,{"2019":58,"2020":58,"2022":58},1,{},{},"JOURNAL",{"meta":63,"data":65},{"total":64},"239",[66,205,422,536,877,983,1125,1220,1316,1423],{"id":67,"createTime":68,"updateTime":69,"relativeEntities":70,"slug":71,"properties":72,"entityType":83,"verifyStatus":84,"verifyTime":85,"verifyNote":86,"languages":18,"translateLanguages":18,"viewCount":19,"primaryUrl":87,"fullTextUrl":18,"authors":88,"publicationType":161,"publisherRelationship":162,"citationCount":19,"citationInfo":197,"publishDate":200,"publishYear":198,"citationAnalyzeStatus":201,"lastCitationAnalyze":202,"indexDatabases":203,"openAccess":18,"references":18,"isForceReanalyzing":204},"4737ad98-e074-4b31-8164-2c3f505643ba","2024-02-05T17:53:51.499+00:00","2026-07-22T19:54:39.530+00:00",[],"COVID-19-associated-mucormycosis-an-update-of-anesthetic-management",{"abstract":73,"title":75,"gsPaper":77,"references":79,"doi":81},{"EN":74},"Mucormycosis is uncommon, progressive fungal infection with mortality rate on higher side. The anesthetic management of surgical debridement in mucormycosis is challenging. We evaluated the anesthetic management of mucormycosis patients associated with problems of airway management, predisposing factors, and adverse effect of antifungal therapy who underwent surgical resection of necrotized tissues. Fifty-six patients presented with uncontrolled diabetes mellitus. All patients had history of COVID-19 infection and received steroid during treatment. Nasal endoscopic debridement was done in 43 patients, total maxillectomy in 14 patients. Temporalis flap was needed in five patients, and orbital exenteration was required in three patients. Central venous catheter was inserted in 17 patients, and invasive arterial monitoring was done in ten patients. All patients administered lyophilized amphotericin B (deoxycholate) in combination with surgical debridement. Thirteen patients were shifted to ICU for further management and continuous hemodynamic monitoring. Fifteen patients were expired, and the mortality rate was 26.31%. Challenges include difficult intubation and renal function impairment due to prolonged antifungal therapy. Postoperative ICU management is important in mucormycosis patients due to comorbidities and rapid progressive infection after surgery.",{"EN":76},"COVID-19-associated mucormycosis: an update of anesthetic management",{"VOID":78},"[\"6111257904411895235\"]",{"VOID":80},"Abramson E, Wilson D, Arky RA (1984) Rhino cerebral phycomycosis in association with diabetic ketoacidosis. Ann Intern Med:1060–1062. https:\u002F\u002Fdoi.org\u002F10.7326\u002F0003-4819-66-4-735\nAlfishawy M, Elbendary A, Younes A, Negm A, Hassan WS, Osman SH, Nassar M, Elanany MG (2021) Diabetes mellitus and coronavirus disease (COVID-19) associated mucormycosis (CAM): a wake-up call from Egypt. Diabetes Metab Syndr Clin Res Rev 15(5):102195. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.dsx.2021.102195\nBavikar P, Mehta V (2017) Rhino-orbital-cerebral mucormycosis: a fatal complication of uncontrolled diabetes mellitus. Cuneus 9(11):e1841. https:\u002F\u002Fdoi.org\u002F10.7759\u002Fcureus.1841\nBitar D, Van Cauteren D, Lanternier F, Dannaoui E, Che D, Dromer F et al (2009) Increasing incidence of zygomycosis (mucormycosis), France, 1997–2006. Emerg. Infect. Dis. 15(9):1395–1401. https:\u002F\u002Fdoi.org\u002F10.3201\u002Feid1509.090334\nBlitzer A, Lawson W, Meyers BR, Biller HF (1980) Patient survival factors in paranasal sinus mucormycosis. Laryngoscope 90:635–648. https:\u002F\u002Fdoi.org\u002F10.1288\u002F00005537-198004000-00010\nÇagatay AA, Öncü SS, Çalangu SS, Yildirmak TT, Özsüt HH, Eraksoy HH (2001) Rhinocerebral mucormycosis treated with 32 gram liposomal amphotericin B and incomplete surgery: a case report. BMC Infect Dis 1:22 http:\u002F\u002Fwww.biomedcentral.com\u002F1471-2334\u002F1\u002F22\nChen N, Zhou M, Dong X, Qu J, Gong F, Han Y, Qiu Y, Wang J, Liu Y, Wei Y, Xia J', Yu T, Zhang X, Zhang L (2020) Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 395(10223):507–513. https:\u002F\u002Fdoi.org\u002F10.1016\u002FS0140-6736(20)30211-7\nEckmann DM, Seligman I, CJ C, Hussong JW (1998) Mucormycosis supraglottitis on induction of anesthesia in an immunocompromised host. Anesth Analg 86(4):729–730. https:\u002F\u002Fdoi.org\u002F10.1213\u002F00000539-199804000-00010\nElihu A, Gollin G (2007) Complications of implanted central venous catheters in neutropenic children. Am Surg 73(10):1079–1082. PMID:17983086. https:\u002F\u002Fdoi.org\u002F10.1177\u002F000313480707301035\nFürbringer P (1876) Beobachtungen über Lungenmycose beim Menschen. Archiv f. pathol. Anat. 66(3):330–365. https:\u002F\u002Fdoi.org\u002F10.1007\u002FBF01878266\nGarg D, Muthu V, Sehgal IS, Ramachandran R, Kaur H, Bhalla A et al (2021) Coronavirus disease (COVID-19) associated mucormycosis (CAM): case report and systematic review of literature. Mycopathologia. https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs11046-021-00528-2\nHirabayashi KE, Kalin-Hajdu E, Brodie FL, Kersten RC, Russell MS, Vagali MZ (2017) Retro bulbar injection of amphotericin B for orbital mucormycosis. Ophthalmic Plast Reconstr Surg. 33(4):e94–e97. https:\u002F\u002Fdoi.org\u002F10.1097\u002FIOP.0000000000000806\nJeong SJ, Lee JU, Song YG, Lee KH, Lee MJ (2015) Delaying diagnostic procedure significantly increases mortality in patients with invasive mucormycosis. Mycoses 58(12):746–752. https:\u002F\u002Fdoi.org\u002F10.1111\u002Fmyc.12428\nJohn BV, Chamilos G, Kontoyiannis DP (2005) Hyperbaric oxygen as an adjunctive treatment for zygomycosis. Clin Microbiol Infect 11(7):515–517. https:\u002F\u002Fdoi.org\u002F10.1111\u002Fj.1469-0691.2005.01170.x\nKaraaslan E (2019) Anesthetic management of rhinoorbitocerebral mucormycosis; focus on challenges. J de Mycologie Me´dicale 29:219–222. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.mycmed.2019.07.001\nKulkarni PK, Reddy NB, Shrinivas B, Takkalki VV (2015) Anesthetic considerations in the management of mucormycosis. Int J Med Public Health 5(4):387–390. https:\u002F\u002Fdoi.org\u002F10.4103\u002F2230-8598.165986\nMehta S, Pandey A (2020) Rhino-orbital mucormycosis associated with COVID-19. Cureus 12(9):e10726. https:\u002F\u002Fdoi.org\u002F10.7759\u002Fcureus.10726\nPetrikkos G, Skiada A, Lortholary O, Roilides E, Walsh TJ, Kontoyiannis DP (2012) Epidemiology and clinical manifestations of mucormycosis. Clin. Infect. Dis. 54(suppl_1):S23–S34. https:\u002F\u002Fdoi.org\u002F10.1093\u002Fcid\u002Fcir866\nPinto ME, Manrique HA, Guevara X, Acosta M, Villena JE, Solis J (2011) Hyperglycemic hyperosmolar state and rhino-orbital mucormycosis. Diabetes Res Clin Pract 91(2):e37–e39. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.diabres.2010-09-038\nSingh AK, Singh R, Joshi SR, Misra A (2021) Mucormycosis in COVID-19: a systematic review of cases reported worldwide and in India. Diabetes Metab Syndr 2021. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.dsx.2021.05.019\nSkiada A, Pavleas I, Drogari-Apiranthitou M (2020) Epidemiology and diagnosis of mucormycosis: An Update J. Fungi 6(4):265. https:\u002F\u002Fdoi.org\u002F10.3390\u002Fjof6040265\nThe RECOVERY Collaborative Group: Dexamethasone in hospitalized patients with Covid-19 – preliminary report. New Engl Med. 2020; 1-11. https:\u002F\u002Fdoi.org\u002F10.1056\u002FNEJMoa2021436 Clinical management protocol for COVID-19. 2020: https:\u002F\u002Fwww.mohfw.gov.in\u002Fpdf\u002FClinical Management Protocol for COVID 19.pdf.\nUyar Y, Kumral TL, Yıldırım G, Kuzdere M, Arbağ H, Jorayev C et al (2015) Reconstruction of the orbit with a temporalis muscle flap after orbital exenteration. Clin Exp otorhinolaryngol 8(1):52–56. https:\u002F\u002Fdoi.org\u002F10.3342\u002Fceo.2015.8\nWali U, Balkhair A, Al-Mujaini A (2012) Cerebro-rhino orbital mucormycosis: an update. J Infect Public Health 5:116–126. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.jiph.2012.01.003\nWalther G, Wagner L, Kurzai O (2019) Updates on the taxonomy of mucorales with an emphasis on clinically important taxa. Fungi 5:106. https:\u002F\u002Fdoi.org\u002F10.3390\u002Fjof5040106\nYohai RA, Bullock JD, Aziz AA, Markert RJ (1994) Survival factors in rhino-orbital cerebral mucormycosis. Surv Ophthalmol 39(1):3–22. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fs0039-6257(05)80041-4",{"VOID":82},"10.1186\u002Fs42077-022-00216-3","PUBLICATION","VERIFIED","2024-06-27T00:45:29.706+00:00","Auto Verify","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1186\u002Fs42077-022-00216-3",[89,105,120,134,147],{"id":90,"sortIndex":19,"researcher":18,"roles":91,"affiliations":93,"properties":102,"displayName":104,"givenName":18,"familyName":18},"079c50fb-4214-4f37-a049-bdb8577010a5",[92],"AUTHOR",[94],{"id":95,"sortIndex":19,"affiliation":96,"properties":18},"4910c90a-80af-4a21-93c0-ee48ae62d08f",{"id":95,"createTime":18,"updateTime":18,"relativeEntities":97,"slug":18,"properties":98,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":101,"statistic":18},[],{"title":99},{"VI":100},"Department of Anesthesia, B. J. Medical College and Civil Hospital, Ahmedabad, India",[],{"title":103},{"VI":104},"Nilesh Maganbhai Solanki",{"id":106,"sortIndex":58,"researcher":18,"roles":107,"affiliations":108,"properties":117,"displayName":119,"givenName":18,"familyName":18},"e3de0eeb-9dbc-43b4-a816-73b76949129a",[92],[109],{"id":110,"sortIndex":19,"affiliation":111,"properties":18},"ba7e8f39-9001-4936-ba3e-75ad2a82be9f",{"id":110,"createTime":18,"updateTime":18,"relativeEntities":112,"slug":18,"properties":113,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":116,"statistic":18},[],{"title":114},{"VI":115},"Department of Anesthesia, GCRI, B. J. Medical College and Civil Hospital, Ahmedabad, India",[],{"title":118},{"VI":119},"Rekha Nilesh Solanki",{"id":121,"sortIndex":122,"researcher":18,"roles":123,"affiliations":124,"properties":131,"displayName":133,"givenName":18,"familyName":18},"5753c0d6-fd2c-41b6-a25f-f0baffec1b60",2,[92],[125],{"id":95,"sortIndex":19,"affiliation":126,"properties":18},{"id":95,"createTime":18,"updateTime":18,"relativeEntities":127,"slug":18,"properties":128,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":130,"statistic":18},[],{"title":129},{"VI":100},[],{"title":132},{"VI":133},"Arun Vrajlal Madaliya",{"id":135,"sortIndex":56,"researcher":18,"roles":136,"affiliations":137,"properties":144,"displayName":146,"givenName":18,"familyName":18},"fe50d8bb-5978-4119-aa55-66f22682c862",[92],[138],{"id":95,"sortIndex":19,"affiliation":139,"properties":18},{"id":95,"createTime":18,"updateTime":18,"relativeEntities":140,"slug":18,"properties":141,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":143,"statistic":18},[],{"title":142},{"VI":100},[],{"title":145},{"VI":146},"Rasmita Haresh Jasoliya",{"id":148,"sortIndex":149,"researcher":18,"roles":150,"affiliations":151,"properties":158,"displayName":160,"givenName":18,"familyName":18},"fe3ebf5a-13f7-4ccd-8992-3ab6e0eec6a8",4,[92],[152],{"id":95,"sortIndex":19,"affiliation":153,"properties":18},{"id":95,"createTime":18,"updateTime":18,"relativeEntities":154,"slug":18,"properties":155,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":157,"statistic":18},[],{"title":156},{"VI":100},[],{"title":159},{"VI":160},"Dhara Tushar Upadhyay","ARTICLE",{"url":87,"publisher":163,"properties":192},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":164,"slug":10,"properties":165,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":168,"manageAffiliations":173,"indexDatabases":179,"url":53,"thumbnailPath":18,"statistic":187,"gsStatistic":18,"type":61,"analyzePriority":18},[],{"issn":166,"title":167},{"VOID":13},{"EN":15},[169],{"id":22,"createTime":18,"updateTime":18,"relativeEntities":170,"label":171,"description":172,"parentId":18,"standard":18,"scholarHubFieldId":18},[],{"EN":25},{},[174],{"id":29,"createTime":18,"updateTime":18,"relativeEntities":175,"slug":18,"properties":176,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":178,"statistic":18},[],{"title":177},{"EN":33},[],[180],{"id":37,"indexDatabase":181,"url":50,"indexYears":18,"academicFieldIds":186,"indexDatabaseRanking":18},{"id":39,"createTime":18,"updateTime":18,"relativeEntities":182,"label":183,"description":184,"key":46,"publicationTags":185,"standard":18},[],{"EN":42,"VI":42},{"EN":44,"VI":45},[48,49],[52],{"impactFactor":19,"impactFactorByYear":188,"i10Index":19,"i10IndexLast5Year":19,"totalPublication":56,"totalPublicationByYear":189,"totalCitation":19,"totalCitationByYear":190,"totalCitationPerPublication":19,"totalCitationPerPublicationByYear":191,"hindexLast5Year":19,"hindex":19},{},{"2019":58,"2020":58,"2022":58},{},{},{"pages":193,"volume":195},{"VOID":194},"1-8",{"VOID":196},"14",{"total":19,"publishYear":198,"statisticByYear":199},2022,{},"2022-02-10","DONE_ANALYZE_CITATION","2026-07-22T19:54:39.529+00:00",[48],false,{"id":206,"createTime":207,"updateTime":208,"relativeEntities":209,"slug":210,"properties":211,"entityType":83,"verifyStatus":84,"verifyTime":224,"verifyNote":86,"languages":225,"translateLanguages":18,"viewCount":19,"primaryUrl":227,"fullTextUrl":18,"authors":228,"publicationType":161,"publisherRelationship":310,"citationCount":19,"citationInfo":345,"publishDate":348,"publishYear":346,"citationAnalyzeStatus":17,"lastCitationAnalyze":208,"indexDatabases":349,"openAccess":18,"references":350,"isForceReanalyzing":204},"90fc8144-f675-42fe-80fa-c8b5e4890c4d","2024-04-18T22:32:44.581+00:00","2026-07-13T14:47:52.077+00:00",[],"Assessment-the-role-of-tranexamic-acid-in-prevention-of-postpartum-hemorrhage",{"openalex":212,"mag":214,"abstract":216,"title":218,"gsPaper":220,"doi":222},{"VOID":213},"W3164310631",{"VOID":215},"3164310631",{"EN":217},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\u003Cjats:sec>\n                \u003Cjats:title>Background\u003C\u002Fjats:title>\n                \u003Cjats:p>Postpartum hemorrhage (PPH) is one of the leading causes of maternal mortality and morbidity worldwide. It is believed that hemostatic imbalance secondary to release of tissue plasminogen activator (tPA) and subsequent hyperfibrinolysis plays a major role in PPH pathogenesis. Antifibrinolytic drugs such as tranexamic acid (TXA) are widely used in hemorrhagic conditions associated with hyperfibrinolysis. TXA reduced maternal death due to PPH and its use as a part of PPH treatment is recommended, and in recent years, a number of trials have investigated the efficacy of prophylactic use of TXA in reducing the incidence and the severity of PPH.\u003C\u002Fjats:p>\n                \u003Cjats:p>The study is aiming to assess the efficacy of tranexamic acid in reducing blood loss throughout and after the lower segment cesarean section and reducing the risk of postpartum hemorrhage.\u003C\u002Fjats:p>\n              \u003C\u002Fjats:sec>\u003Cjats:sec>\n                \u003Cjats:title>Results\u003C\u002Fjats:title>\n                \u003Cjats:p>The amount of blood loss was significantly lower in the study group than the control group (416.12±89.95 and 688.68±134.77 respectively). Also the 24-h postoperative hemoglobin was significantly higher in the study group (11.66±0.79 mg\u002Fdl) compared to the control group (10.53±1.07mg\u002Fdl), and the 24-h postoperative hematocrit value was significantly higher in the study group (34.99±2.40) compared to control (31.62±3.22).\u003C\u002Fjats:p>\n              \u003C\u002Fjats:sec>\u003Cjats:sec>\n                \u003Cjats:title>Conclusion\u003C\u002Fjats:title>\n                \u003Cjats:p>Prophylactic administration of tranexamic acid reduces intraoperative and postoperative bleeding in cesarean section and the incidence of postpartum hemorrhage.\u003C\u002Fjats:p>\n              \u003C\u002Fjats:sec>",{"EN":219},"Assessment the role of tranexamic acid in prevention of postpartum hemorrhage",{"VOID":221},"[\"14301733018623537781\"]",{"VOID":223},"10.1186\u002Fs42077-021-00154-6","2024-05-14T07:47:17.343+00:00",[226],"EN","https:\u002F\u002Flink.springer.com\u002F10.1186\u002Fs42077-021-00154-6",[229,246,261,278,295],{"id":230,"sortIndex":19,"researcher":18,"roles":231,"affiliations":232,"properties":241,"displayName":243,"givenName":18,"familyName":18},"899cdcf2-38fb-4cbd-a347-dd8c132e7cf1",[],[233],{"id":234,"sortIndex":19,"affiliation":235,"properties":18},"609246eb-75b4-4d07-8f50-686fa18d218a",{"id":234,"createTime":18,"updateTime":18,"relativeEntities":236,"slug":18,"properties":237,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":240,"statistic":18},[],{"title":238},{"EN":239},"Department of Anesthesiology, Intensive care and Pain Management, Faculty of Medicine, Ain-Shams University, Abbassia, Cairo, 11591, Egypt",[],{"title":242,"openalex":244},{"EN":243},"Nevein Gerges Fahmy",{"VOID":245},"A5044778082",{"id":247,"sortIndex":58,"researcher":18,"roles":248,"affiliations":249,"properties":256,"displayName":258,"givenName":18,"familyName":18},"e40a7462-3897-4b98-beb4-20ecd19d6f5b",[],[250],{"id":234,"sortIndex":19,"affiliation":251,"properties":18},{"id":234,"createTime":18,"updateTime":18,"relativeEntities":252,"slug":18,"properties":253,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":255,"statistic":18},[],{"title":254},{"EN":239},[],{"title":257,"openalex":259},{"EN":258},"Fahmy Saad Latif 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Khalil",{"VOID":277},"A5062256276",{"id":279,"sortIndex":56,"researcher":18,"roles":280,"affiliations":281,"properties":288,"displayName":292,"givenName":18,"familyName":18},"026138b2-d6bc-4ef2-a034-136d6932616c",[],[282],{"id":234,"sortIndex":19,"affiliation":283,"properties":18},{"id":234,"createTime":18,"updateTime":18,"relativeEntities":284,"slug":18,"properties":285,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":287,"statistic":18},[],{"title":286},{"EN":239},[],{"orcid":289,"title":291,"openalex":293},{"VOID":290},"https:\u002F\u002Forcid.org\u002F0000-0003-1074-2967",{"EN":292},"Mohammed Ibrahim Ibrahim Sobhy",{"VOID":294},"A5021924240",{"id":296,"sortIndex":149,"researcher":18,"roles":297,"affiliations":298,"properties":305,"displayName":307,"givenName":18,"familyName":18},"4b739665-5bb0-4da2-9057-9b8dffc136c7",[],[299],{"id":234,"sortIndex":19,"affiliation":300,"properties":18},{"id":234,"createTime":18,"updateTime":18,"relativeEntities":301,"slug":18,"properties":302,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":304,"statistic":18},[],{"title":303},{"EN":239},[],{"title":306,"openalex":308},{"EN":307},"Amin Mohammed Al Ansary Amin",{"VOID":309},"A5041632158",{"url":18,"publisher":311,"properties":340},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":312,"slug":10,"properties":313,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":316,"manageAffiliations":321,"indexDatabases":327,"url":53,"thumbnailPath":18,"statistic":335,"gsStatistic":18,"type":61,"analyzePriority":18},[],{"issn":314,"title":315},{"VOID":13},{"EN":15},[317],{"id":22,"createTime":18,"updateTime":18,"relativeEntities":318,"label":319,"description":320,"parentId":18,"standard":18,"scholarHubFieldId":18},[],{"EN":25},{},[322],{"id":29,"createTime":18,"updateTime":18,"relativeEntities":323,"slug":18,"properties":324,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":326,"statistic":18},[],{"title":325},{"EN":33},[],[328],{"id":37,"indexDatabase":329,"url":50,"indexYears":18,"academicFieldIds":334,"indexDatabaseRanking":18},{"id":39,"createTime":18,"updateTime":18,"relativeEntities":330,"label":331,"description":332,"key":46,"publicationTags":333,"standard":18},[],{"EN":42,"VI":42},{"EN":44,"VI":45},[48,49],[52],{"impactFactor":19,"impactFactorByYear":336,"i10Index":19,"i10IndexLast5Year":19,"totalPublication":56,"totalPublicationByYear":337,"totalCitation":19,"totalCitationByYear":338,"totalCitationPerPublication":19,"totalCitationPerPublicationByYear":339,"hindexLast5Year":19,"hindex":19},{},{"2019":58,"2020":58,"2022":58},{},{},{"issue":341,"volume":343},{"VOID":342},"1",{"VOID":344},"13",{"total":19,"publishYear":346,"statisticByYear":347},2021,{},"2021-12-01",[48],[351,355,359,362,366,370,374,378,382,386,390,394,398,402,406,410,414,418],{"id":18,"text":352,"url":18,"identifiers":353},"Abdel-Aleem H, Alhusaini TK, Abdel-Aleem MA, Menoufy M, Gülmezoglu AM (2013) Effectiveness of tranexamic acid on blood loss in patients undergoing elective cesarean section: randomized clinical trial. J Matern Neonatal Med 26(17):1705–1709 [cited 2021 Jan 10]",{"doi":354},"10.3109\u002F14767058.2013.794210",{"id":18,"text":356,"url":18,"identifiers":357},"Alam A, Bopardikar A, Au S, Barrett J, Callum J, Kiss A et al (2017) Protocol for a pilot, randomised, double-blinded, placebo-controlled trial of prophylactic use of tranexamic acid for preventing postpartum haemorrhage (TAPPH-1). BMJ Open 7(10):1–8",{"doi":358},"10.1136\u002Fbmjopen-2017-018586",{"id":18,"text":360,"url":18,"identifiers":361},"Butterworth J, Mackey DC, Wasnick J (2013) Chapter 51. Fluid Management & Blood Component Therapy. In: Morgan & Mikhail’s clinical anesthesiology, 5e | AccessMedicine McGraw-Hill Medical [Internet]. [cited 2021 Jan 10]. McGraw-Hill, New York, p 1168",{},{"id":18,"text":363,"url":18,"identifiers":364},"Committee on Practice Bulletins-Obstetrics (2017) Practice bulletin no. 183: postpartum hemorrhage. Obstet Gynecol 130(4):e168–e186. https:\u002F\u002Fdoi.org\u002F10.1097\u002FAOG.0000000000002351",{"doi":365},"10.1097\u002FAOG.0000000000002351",{"id":18,"text":367,"url":18,"identifiers":368},"Ducloy-Bouthors A-S, Jeanpierre E, Saidi I, Baptiste A-S, Simon E, Lannoy D et al (2018) TRAnexamic acid in hemorrhagic CESarean section (TRACES) randomized placebo controlled dose-ranging pharmacobiological ancillary trial: study protocol for a randomized controlled trial. Trials 19(1):1–16.",{"doi":369},"10.1186\u002Fs13063-017-2421-6",{"id":18,"text":371,"url":18,"identifiers":372},"Kandappan G, Anand B (2016) Efficacy of tranexamic acid in decreasing blood loss during and after cesarean section in multigravida parturients: a case controlled prospective study. J Evid Based Med Healthc 3(48):2419–2425. https:\u002F\u002Fdoi.org\u002F10.18410\u002Fjebmh\u002F2016\u002F532",{"doi":373},"10.18410\u002Fjebmh\u002F2016\u002F532",{"id":18,"text":375,"url":18,"identifiers":376},"Lier H, Maegele M, Shander A (2019) Tranexamic acid for acute hemorrhage: a narrative review of landmark studies and a critical reappraisal of its use over the last decade. Anesth Analg 129(6):1574–1584. https:\u002F\u002Fdoi.org\u002F10.1213\u002FANE.0000000000004389",{"doi":377},"10.1213\u002FANE.0000000000004389",{"id":18,"text":379,"url":18,"identifiers":380},"Neb H, Zacharowski K, Meybohm P (2017) Strategies to reduce blood product utilization in obstetric practice. Curr Opin Anaesthesiol 30(3):294–299. https:\u002F\u002Fdoi.org\u002F10.1097\u002FACO.0000000000000463",{"doi":381},"10.1097\u002FACO.0000000000000463",{"id":18,"text":383,"url":18,"identifiers":384},"Pabinger I, Fries D, Schöchl H, Streif W, Toller W (2017) Tranexamic acid for treatment and prophylaxis of bleeding and hyperfibrinolysis. Wien Klin Wochenschr 129(9–10):303–316. https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs00508-017-1194-y",{"doi":385},"10.1007\u002Fs00508-017-1194-y",{"id":18,"text":387,"url":18,"identifiers":388},"Pacheco LD, Hankins GDV, Saad AF, Costantine MM, Chiossi G, Saade GR (2017) Tranexamic acid for the management of obstetric hemorrhage. Obstet Gynecol 130(4):765–769. https:\u002F\u002Fdoi.org\u002F10.1097\u002FAOG.0000000000002253",{"doi":389},"10.1097\u002FAOG.0000000000002253",{"id":18,"text":391,"url":18,"identifiers":392},"Pacheco LD, Saade GR, Hankins GDV (2019) Medical management of postpartum hemorrhage: an update. Semin Perinatol 43(1):22–26. https:\u002F\u002Fdoi.org\u002F10.1053\u002Fj.semperi.2018.11.005",{"doi":393},"10.1053\u002Fj.semperi.2018.11.005",{"id":18,"text":395,"url":18,"identifiers":396},"Roberts I, Shakur H, Coats T, Hunt B, Balogun E, Barnetson L, Cook L, Kawahara T, Perel P, Prieto-Merino D, Ramos M, Cairns J, Guerriero C (2013) The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients. Health Technol Assess 17(10):1–79. https:\u002F\u002Fdoi.org\u002F10.3310\u002Fhta17100",{"doi":397},"10.3310\u002Fhta17100",{"id":18,"text":399,"url":18,"identifiers":400},"Salem M, Mohamed M, Salem A, Abbas A (2016) Tranexamic acid as prophylactic therapy for intra and post partum hemorrhage, randomized controlled trial. Br J Med Med Res 17(2):1–7. https:\u002F\u002Fdoi.org\u002F10.9734\u002FBJMMR\u002F2016\u002F26288",{"doi":401},"10.9734\u002FBJMMR\u002F2016\u002F26288",{"id":18,"text":403,"url":18,"identifiers":404},"Sentilhes L, Daniel V, Deneux-Tharaux C (2020) TRAAP2-TRAnexamic acid for preventing postpartum hemorrhage after cesarean delivery: a multicenter randomized, doubleblind, placebo-controlled trial- a study protocol. BMC Pregnancy Childbirth 20(1):1–11",{"doi":405},"10.1186\u002Fs12884-019-2718-4",{"id":18,"text":407,"url":18,"identifiers":408},"Sentürk MB, Cakmak Y, Yildiz G, Yildiz P (2013) Tranexamic acid for cesarean section: a double-blind, placebo-controlled, randomized clinical trial. Arch Gynecol Obstet 287(4):641–645. https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs00404-012-2624-8",{"doi":409},"10.1007\u002Fs00404-012-2624-8",{"id":18,"text":411,"url":18,"identifiers":412},"Shakur H, Roberts I, Fawole B, Chaudhri R, El-Sheikh M, Akintan A et al (2017) Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial. Lancet. 389(10084):2105–2116. https:\u002F\u002Fdoi.org\u002F10.1016\u002FS0140-6736(17)30638-4",{"doi":413},"10.1016\u002FS0140-6736(17)30638-4",{"id":18,"text":415,"url":18,"identifiers":416},"Solomon C, Collis RE, Collins PW (2012) Haemostatic monitoring during postpartum haemorrhage and implications for management. Br J Anaesth 109(6):851–863. https:\u002F\u002Fdoi.org\u002F10.1093\u002Fbja\u002Faes361",{"doi":417},"10.1093\u002Fbja\u002Faes361",{"id":18,"text":419,"url":18,"identifiers":420},"Xu J, Gao W, Ju Y (2013) Tranexamic acid for the prevention of postpartum hemorrhage after cesarean section: a double-blind randomization trial. Arch Gynecol Obstet 287(3):463–468. https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs00404-012-2593-y",{"doi":421},"10.1007\u002Fs00404-012-2593-y",{"id":423,"createTime":424,"updateTime":425,"relativeEntities":426,"slug":427,"properties":428,"entityType":83,"verifyStatus":84,"verifyTime":439,"verifyNote":86,"languages":18,"translateLanguages":18,"viewCount":19,"primaryUrl":440,"fullTextUrl":18,"authors":441,"publicationType":161,"publisherRelationship":496,"citationCount":19,"citationInfo":531,"publishDate":534,"publishYear":532,"citationAnalyzeStatus":17,"lastCitationAnalyze":425,"indexDatabases":535,"openAccess":18,"references":18,"isForceReanalyzing":204},"18d73aa5-015f-4cad-80ad-95e3652ac3f2","2024-02-14T09:16:58.397+00:00","2026-07-12T07:50:50.532+00:00",[],"Postoperative-analgesia-in-children-undergoing-adenotonsillectomy-under-sevoflurane-versus-propofol-based-anesthesia-a-randomized-controlled-trial",{"abstract":429,"title":431,"gsPaper":433,"references":435,"doi":437},{"EN":430},"The field of pediatric pain management has changed greatly in the past decades. However, the number of children who experience moderate-to-severe postoperative pain, even with analgesic treatment, remains significant. If an intravenous or inhalational anesthetic would include in itself all components of general anesthesia, such as hypnosis, analgesia, and amnesia, it would represent an ideal anesthetic. There are some pieces of evidence that propofol may reduce postoperative pain. This debate on the early potential analgesic efficacy of propofol compared with sevoflurane during the postoperative period in children was evident. The aim of this study is to compare the postoperative potential analgesic effects of propofol-based versus sevoflurane-based anesthesia in children undergoing adenotonsillectomy. This study was a prospective comparative randomized, double-blinded trial conducted on 60 children between 3 and 10 years of age and American Society of Anesthesiologists physical status I and ІІ undergoing adenotonsillectomy under general anesthesia. Patients were randomly assigned to one of the following two equal groups: the sevoflurane group and the propofol group. The primary outcome was pain score assessed using the Faces Pain Scale postoperatively. The secondary outcomes included recovery time and adverse events within the first 4 h. The current study showed that the postoperative resting and swallowing face pain score was significantly lower in the propofol group than in the sevoflurane group, and postoperative agitation scores were significantly lower in the propofol group than in the sevoflurane group during the first 30 min of early postoperative period. No significant differences were found from 40 min to the fourth postoperative hour. Paracetamol consumption during the 4-h postoperative period was significantly greater in the sevoflurane group than in the propofol group, and the incidence of postoperative nausea and vomiting was lower in the propofol group than in the sevoflurane group (P = 0.001). The use of propofol is more advantageous compared with sevoflurane for the induction and maintenance of general anesthesia in children undergoing adenotonsillectomy. It decreases early postoperative pain, analgesic consumption, postoperative agitation, and postoperative nausea and vomiting. However, the use of propofol in the induction and maintenance of anesthesia is associated with a prolonged recovery time.",{"EN":432},"Postoperative analgesia in children undergoing adenotonsillectomy under sevoflurane versus propofol-based anesthesia: a randomized controlled trial",{"VOID":434},"[\"2886505681015455598\"]",{"VOID":436},"Anker-Møller E, Spangsberg N, Arendt-Nielsen L, Schultz P, Kristensen MS, Bjerring P (1991) Subhypnotic doses of thiopentone and propofol cause analgesia to experimentally induced acute pain. Br J Anaesth 66:185–188\nAono J, Ueda W, Mamiya K, Takimoto E, Manabe M (1997) Greater incidence of delirium during recovery from sevoflurane anesthesia in preschool boys. Anesthesiology 87:1298–1300\nBandschapp O, Filitz J, Ihmsen H, Berset A, Urwyler A, Koppert W, Ruppen W (2010) Analgesic and antihyperalgesic properties of propofol in a human pain model. Anesthesiology 113:421–428. https:\u002F\u002Fdoi.org\u002F10.1097\u002FALN.0b013e3181e33ac8\nBerde CB, Sethna NF (2002) Analgesics for the treatment of pain in children. N Engl J Med 347:1094–1103. https:\u002F\u002Fdoi.org\u002F10.1056\u002FNEJMra012626\nCheng SS, Yeh J, Flood P (2008) Anesthesia matters: patients anesthetized with propofol have less postoperative pain than those anesthetized with isoflurane. Anesth Analg 106:264–269. https:\u002F\u002Fdoi.org\u002F10.1213\u002F01.ane.0000287653.77372.d9\nDong XP, Xu TL (2002) The actions of propofol on gamma-aminobutyric acid-A and glycine receptors in acutely dissociated spinal dorsal horn neurons of the rat. Anesth Analg 95:907–914\nFassoulaki A, Melemeni A, Paraskeva A, Siafaka I, Sarantopoulos C (2008) Postoperative pain and analgesic requirements after anesthesia with sevoflurane, desflurane or propofol. Anesth Analg 107:1715–1719. https:\u002F\u002Fdoi.org\u002F10.1213\u002Fane.0b013e318182d84e\nGinosar Y, Davidson EM, Meroz Y, Blotnick S, Shacham M, Caraco Y (2009) Mu-opioid receptor (A118G) single-nucleotide polymorphism affects alfentanil requirements for extracorporeal shock wave lithotripsy: a pharmacokinetic-pharmacodynamic study. Br J Anaesth 103:420–427. https:\u002F\u002Fdoi.org\u002F10.1093\u002Fbja\u002Faep192 Epub 2009 Jul 15\nHasani A, Gecaj-Gashi A, Llullaku S, Jashari H (2003) Postoperative analgesia in children after propofol versus sevoflurane anesthesia. Pain Med 14:442–446. https:\u002F\u002Fdoi.org\u002F10.1111\u002Fpme.12031\nHasani A, Jashari H, Gashi V, Dervishi A (2012) Propofol and postoperative pain: systematic review and metaanalysis. In: Racz GB, Noe CE (eds) Pain Management—Current Issues and Opinions. 012:223–242 Gabor B. Racz and Carl E. Noe, IntechOpen. https:\u002F\u002Fdoi.org\u002F10.5772\u002F30974 Available from: https:\u002F\u002Fwww.intechopen.com\u002Fbooks\u002Fpain-management-current-issues-and-opinions\u002Fpropofol-and-postoperative-pain-systematic-review-and-meta-analysis\nHoward R, Carter B, Curry J, Morton N, Rivett K, Rose M, Tyrrell J, Walker S, Williams G (2008) Association of Paediatric Anaesthetists of Great Britain and Ireland: pain assessment. Paediatr Anaesth 18:14–18. https:\u002F\u002Fdoi.org\u002F10.1111\u002Fj.1155-5645.2008.02429.x\nHunter M, McDowell L, Hennessy R, Cassey J (2000) An evaluation of the faces pain scale with young children. J Pain Symptom Manag 20:122–129\nJewett BA, Gibbs LM, Tarasiuk A, Kendig JJ (1992) Propofol and barbiturate depression of spinal nociceptive neurotransmission. Anesthesiology 77:1148–1154\nLi M, Mei W, Wang P, Yu Y, Qian W, Zhang ZG, Tian YK (2012) Propofol reduces early post-operative pain after gynecological laparoscopy. Acta Anaesthesiol Scand 56:368–375. https:\u002F\u002Fdoi.org\u002F10.1111\u002Fj.1399-6576.2011.02603.x Epub 2011 Dec 23\nOwen H, McMillan V, Rogowski D (1990) Postoperative pain therapy: a survey of patients’ expectations and their experiences. Pain 41:303–307\nPieters BJ, Penn E, Nicklaus P, Bruegger D, Mehta B, Weatherly R (2010) Emergence delirium and postoperative pain in children undergoing adenotonsillectomy: a comparison of propofol vs sevoflurane anesthesia. Paediatr Anaesth 20(10):944–950. https:\u002F\u002Fdoi.org\u002F10.1111\u002Fj.1460-9592.2010.03394.x\nShafer SL, Nekhendzy V (2008) Anesthesia matters: statistical anomaly or new paradigm? Anesth Analg 106:3–4. https:\u002F\u002Fdoi.org\u002F10.1213\u002F01.ane.0000299045.22629.86\nShin SW, Cho AR, Lee HJ, Kim HJ, Byeon GJ, Yoon JW, Kim KH, Kwon JY (2010) Maintenance anaesthetics during remifentanil-based anaesthesia might affect postoperative pain control after breast cancer surgery. Br J Anaesth 105:661–667. https:\u002F\u002Fdoi.org\u002F10.1093\u002Fbja\u002Faeq257 Epub 2010 Sep 28\nSun YY, Li KC, Chen J (2005) Evidence for peripherally antinociceptive action of propofol in rats: behavioral and spinal neuronal responses to subcutaneous bee venom. Brain Res 1043:231–235\nSvensson I, Sjostrom B, Haljamae H (2000) Assessment of pain experiences after elective surgery. J Pain Symptom Manag 20:193–201\nTan T, Bhinder R, Carey M, Briggs L (2010) Day-surgery patients anesthetized with propofol have less postoperative pain than those anesthetized with sevoflurane. Anesth Analg 111:83–85. https:\u002F\u002Fdoi.org\u002F10.1213\u002FANE.0b013e3181c0ee9e Epub 2009 Nov 12\nThomas T, Robison C, Champion D, McKell M, Pell M (1998) Prediction and assessment of the severity of post-operative pain and of satisfaction with management. Pain 75:177–185\nTorri G (2010) Inhalation anesthetics: a review. Minerva Anestesiol 76:215–228\nToscano A, Pancaro C, Giovannoni S, Minelli G, Baldi C, Guerrieri G, Crowhurst JA, Peduto VA (2003) Sevoflurane analgesia in obstetrics: a pilot study. Int J Obstet Anesth 12:79–82\nYamakura T, Harris RA (2000) Effects of gaseous anesthetics nitrous oxide and xenon on ligandgated ion channels..Comparison with isoflurane and ethanol. Anesthesiology 93:1095–1101",{"VOID":438},"10.1186\u002Fs42077-019-0032-z","2024-05-08T03:25:50.579+00:00","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1186\u002Fs42077-019-0032-z",[442,457,470,483],{"id":443,"sortIndex":19,"researcher":18,"roles":444,"affiliations":445,"properties":454,"displayName":456,"givenName":18,"familyName":18},"1b535775-88d8-443d-b14e-2ae7f41974ad",[92],[446],{"id":447,"sortIndex":19,"affiliation":448,"properties":18},"6d082899-6d6e-44be-b905-91c7dc768de6",{"id":447,"createTime":18,"updateTime":18,"relativeEntities":449,"slug":18,"properties":450,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":453,"statistic":18},[],{"title":451},{"VI":452},"Department of anesthesia & ICU, Faculty of Medicine, Suez Canal University, Ismailia, Egypt",[],{"title":455},{"VI":456},"Hossam M. Atef",{"id":458,"sortIndex":58,"researcher":18,"roles":459,"affiliations":460,"properties":467,"displayName":469,"givenName":18,"familyName":18},"e90cc622-37ed-42b4-b88e-4e96f6727f9f",[92],[461],{"id":447,"sortIndex":19,"affiliation":462,"properties":18},{"id":447,"createTime":18,"updateTime":18,"relativeEntities":463,"slug":18,"properties":464,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":466,"statistic":18},[],{"title":465},{"VI":452},[],{"title":468},{"VI":469},"Salah A. Ismail",{"id":471,"sortIndex":122,"researcher":18,"roles":472,"affiliations":473,"properties":480,"displayName":482,"givenName":18,"familyName":18},"9a263b49-19e6-432f-9d0b-5682332ef960",[92],[474],{"id":447,"sortIndex":19,"affiliation":475,"properties":18},{"id":447,"createTime":18,"updateTime":18,"relativeEntities":476,"slug":18,"properties":477,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":479,"statistic":18},[],{"title":478},{"VI":452},[],{"title":481},{"VI":482},"Ahmad Al-Touny",{"id":484,"sortIndex":56,"researcher":18,"roles":485,"affiliations":486,"properties":493,"displayName":495,"givenName":18,"familyName":18},"47e2ffeb-1a30-43a6-985f-2ee7fd2062b9",[92],[487],{"id":447,"sortIndex":19,"affiliation":488,"properties":18},{"id":447,"createTime":18,"updateTime":18,"relativeEntities":489,"slug":18,"properties":490,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":492,"statistic":18},[],{"title":491},{"VI":452},[],{"title":494},{"VI":495},"Sherif Eid Ahmed Abo-rehab",{"url":440,"publisher":497,"properties":526},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":498,"slug":10,"properties":499,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":502,"manageAffiliations":507,"indexDatabases":513,"url":53,"thumbnailPath":18,"statistic":521,"gsStatistic":18,"type":61,"analyzePriority":18},[],{"issn":500,"title":501},{"VOID":13},{"EN":15},[503],{"id":22,"createTime":18,"updateTime":18,"relativeEntities":504,"label":505,"description":506,"parentId":18,"standard":18,"scholarHubFieldId":18},[],{"EN":25},{},[508],{"id":29,"createTime":18,"updateTime":18,"relativeEntities":509,"slug":18,"properties":510,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":512,"statistic":18},[],{"title":511},{"EN":33},[],[514],{"id":37,"indexDatabase":515,"url":50,"indexYears":18,"academicFieldIds":520,"indexDatabaseRanking":18},{"id":39,"createTime":18,"updateTime":18,"relativeEntities":516,"label":517,"description":518,"key":46,"publicationTags":519,"standard":18},[],{"EN":42,"VI":42},{"EN":44,"VI":45},[48,49],[52],{"impactFactor":19,"impactFactorByYear":522,"i10Index":19,"i10IndexLast5Year":19,"totalPublication":56,"totalPublicationByYear":523,"totalCitation":19,"totalCitationByYear":524,"totalCitationPerPublication":19,"totalCitationPerPublicationByYear":525,"hindexLast5Year":19,"hindex":19},{},{"2019":58,"2020":58,"2022":58},{},{},{"pages":527,"volume":529},{"VOID":528},"1-10",{"VOID":530},"11",{"total":19,"publishYear":532,"statisticByYear":533},2019,{},"2019-05-22",[48],{"id":537,"createTime":538,"updateTime":539,"relativeEntities":540,"slug":541,"properties":542,"entityType":83,"verifyStatus":84,"verifyTime":553,"verifyNote":86,"languages":554,"translateLanguages":18,"viewCount":19,"primaryUrl":555,"fullTextUrl":18,"authors":556,"publicationType":161,"publisherRelationship":610,"citationCount":19,"citationInfo":640,"publishDate":642,"publishYear":198,"citationAnalyzeStatus":17,"lastCitationAnalyze":643,"indexDatabases":644,"openAccess":18,"references":645,"isForceReanalyzing":204},"882c3a16-0871-4971-802a-10488584b29b","2024-04-14T11:37:45.452+00:00","2026-04-24T10:18:55.239+00:00",[],"Hypertonic-saline-in-ICU-setting-what-is-its-position-A-systematic-review-and-empirical-analysis",{"openalex":543,"abstract":545,"title":547,"gsPaper":549,"doi":551},{"VOID":544},"W4286560397",{"EN":546},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\u003Cjats:sec>\n                \u003Cjats:title>Background\u003C\u002Fjats:title>\n                \u003Cjats:p>Fluid overload has been linked to poor outcomes in the critically ill in recent years, with multiple studies showing an increase in mortality in the overall intensive care unit population. Although the administration of hypertonic saline has increased in recent years, few publications involving its use in intensive care unit have been published to date. The aim of this systematic review is to compare hypertonic and isotonic saline solutions and assess the current evidence to determine whether hypertonic saline can be used in the intensive care unit to treat critically ill or injured patients.\u003C\u002Fjats:p>\n              \u003C\u002Fjats:sec>\u003Cjats:sec>\n                \u003Cjats:title>Main body\u003C\u002Fjats:title>\n                \u003Cjats:p>The PRISMA protocol was applied to conduct the search, which generated 622 possible trials. Only four papers were chosen and included in our study after duplicates and studies that did not fulfill our inclusion criteria, and outcomes were removed. The primary outcome was mortality, with the length of time spent in intensive care and in the hospital as secondary outcomes, and patients assessed in the intensive care unit ranged from 3 to 55, according to our revision. There were three to 24 trials in all, and not all of them used mortality or intensive care unit stay as an endpoint. The concentration of HS used in the intervention group ranged from 1.4 to 30%, while not all studies used isotonic saline solution as a control group.\u003C\u002Fjats:p>\n              \u003C\u002Fjats:sec>\u003Cjats:sec>\n                \u003Cjats:title>Conclusions\u003C\u002Fjats:title>\n                \u003Cjats:p>Despite the limited scientific evidence, there seems to be support for the administration\u002Fuse of hypertonic saline in the intensive care unit setting, in highly selected circumstance. Although hypertonic saline may have favorable therapeutic effects, no effect on mortality has been demonstrated. Patients suffering from a traumatic brain injury evidence suggests that hypertonic saline can effectively lower intracranial pressure, and there is a new trend supporting the use of hypertonic sodium solutions in these situations. Our updated review shows that studies still have a lot of variability, and that more controlled research are needed.\u003C\u002Fjats:p>\n              \u003C\u002Fjats:sec>",{"EN":548},"Hypertonic saline in ICU setting: what is its position? 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Neurol Res 28(3):360–366. https:\u002F\u002Fdoi.org\u002F10.1179\u002F016164106X110346",{"doi":765},"10.1179\u002F016164106X110346",{"id":18,"text":767,"url":18,"identifiers":768},"Lee J, de Louw E, Niemi M, Nelson R, Mark RG, Celi LA et al (2015) Association between fluid balance and survival in critically ill patients. J Intern Med 277(4):468–477. https:\u002F\u002Fdoi.org\u002F10.1111\u002Fjoim.12274",{"doi":769},"10.1111\u002Fjoim.12274",{"id":18,"text":771,"url":18,"identifiers":772},"Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP et al (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med 6(7):e1000100. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.jclinepi.2009.06.006",{"doi":773},"10.1016\u002Fj.jclinepi.2009.06.006",{"id":18,"text":775,"url":18,"identifiers":776},"Lu YQ, Cai XJ, Gu LH, Mu HZ, Huang WD (2007) Hypertonic saline resuscitation maintains a more balanced profile of T-lymphocyte subpopulations in a rat model of hemorrhagic shock. J Zhejiang Univ Sci B 8(1):70–75. https:\u002F\u002Fdoi.org\u002F10.1631\u002Fjzus.2007.B0070",{"doi":777},"10.1631\u002Fjzus.2007.B0070",{"id":18,"text":779,"url":18,"identifiers":780},"Magee G, Zbrozek A (2013) Fluid overload is associated with increases in length of stay and hospital costs: pooled analysis of data from more than 600 US hospitals. CEOR 5:289–296. https:\u002F\u002Fdoi.org\u002F10.2147\u002FCEOR.S45873",{"doi":781},"10.2147\u002FCEOR.S45873",{"id":18,"text":783,"url":18,"identifiers":784},"Mangat HS, Wu X, Gerber LM, Schwarz JT, Fakhar M, Murthy SB et al (2020) Hypertonic saline is superior to mannitol for the combined effect on intracranial pressure and cerebral perfusion pressure burdens in patients with severe traumatic brain injury. Neurosurgery. 86(2):221–230. https:\u002F\u002Fdoi.org\u002F10.1093\u002Fneuros\u002Fnyz046",{"doi":785},"10.1093\u002Fneuros\u002Fnyz046",{"id":18,"text":787,"url":18,"identifiers":788},"Marko NF (2012) Hypertonic saline, not mannitol, should be considered gold-standard medical therapy for intracranial hypertension. Crit Care 16(1):113. https:\u002F\u002Fdoi.org\u002F10.1186\u002Fcc11182",{"doi":789},"10.1186\u002Fcc11182",{"id":18,"text":791,"url":18,"identifiers":792},"Mitchell KH, Carlbom D, Caldwell E, Leary PJ, Himmelfarb J, Hough CL (2015) Volume overload: prevalence, risk factors, and functional outcome in survivors of septic shock. Ann Am Thorac Soc 12(12):1837–1844. https:\u002F\u002Fdoi.org\u002F10.1513\u002FAnnalsATS.201504-187OC",{"doi":793},"10.1513\u002FAnnalsATS.201504-187OC",{"id":18,"text":795,"url":18,"identifiers":796},"Page MJ, Moher D, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD et al (2021) PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews. BMJ 372:n160. https:\u002F\u002Fdoi.org\u002F10.1136\u002Fbmj.n160",{"doi":797},"10.1136\u002Fbmj.n160",{"id":18,"text":799,"url":18,"identifiers":800},"Parrinello G, Paterna S, Di Pasquale P, Torres D, Mezzero M, Cardillo M et al (2011) Changes in estimating echocardiography pulmonary capillary wedge pressure after hypersaline plus furosemide versus furosemide alone in decompensated heart failure. J Card Fail 17(4):331–339. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.cardfail.2010.11.003",{"doi":801},"10.1016\u002Fj.cardfail.2010.11.003",{"id":18,"text":803,"url":18,"identifiers":804},"Pfortmueller CA, Schefold JC (2017) Hypertonic saline in critical illness - a systematic review. J Crit Care 42:168–177. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.jcrc.2017.06.019",{"doi":805},"10.1016\u002Fj.jcrc.2017.06.019",{"id":18,"text":807,"url":18,"identifiers":808},"Qureshi AI, Suarez JI (2000) Use of hypertonic saline solutions in treatment of cerebral edema and intracranial hypertension. Crit Care Med 28(9):3301–3301. https:\u002F\u002Fdoi.org\u002F10.1097\u002F00003246-200009000-00032",{"doi":809},"10.1097\u002F00003246-200009000-00032",{"id":18,"text":811,"url":18,"identifiers":812},"Ramires JA, Serrano Júnior CV, César LA, Velasco IT, Rocha e Silva Júnior M, Pileggi F (1992) Acute hemodynamic effects of hypertonic (7.5%) saline infusion in patients with cardiogenic shock due to right ventricular infarction. Circ Shock 37(3):220–225 PMID: 1423912",{},{"id":18,"text":814,"url":18,"identifiers":815},"Rocha e Silva M (2014) Hypertonic saline for treatment of shock. Med Express 1(1):14–21. https:\u002F\u002Fdoi.org\u002F10.5935\u002FMedicalExpress.2014.01.04",{"doi":816},"10.5935\u002FMedicalExpress.2014.01.04",{"id":18,"text":818,"url":18,"identifiers":819},"Rocha-e-Silva M, Poli de Figueiredo LF (2005) Small volume hypertonic resuscitation of circulatory shock. Clinics (Sao Paulo) 60(2):159–172. https:\u002F\u002Fdoi.org\u002F10.1590\u002Fs1807-59322005000200013",{"doi":820},"10.1590\u002Fs1807-59322005000200013",{"id":18,"text":822,"url":18,"identifiers":823},"Severs D, Rookmaaker MB, Hoorn EJ (2015) Intravenous solutions in the care of patients with volume depletion and electrolyte abnormalities. Am J Kidney Dis 66(1):147–153. https:\u002F\u002Fdoi.org\u002F10.1053\u002Fj.ajkd.2015.01.031",{"doi":824},"10.1053\u002Fj.ajkd.2015.01.031",{"id":18,"text":826,"url":18,"identifiers":827},"Shackford SR, Bourguignon PR, Wald SL, Rogers FB, Osler TM, Clark D (1998) Hypertonic saline resuscitation of patients with head injury: a prospective, randomized clinical trial. J Trauma 44:50–58. https:\u002F\u002Fdoi.org\u002F10.1097\u002F00005373-199801000-00004",{"doi":828},"10.1097\u002F00005373-199801000-00004",{"id":18,"text":830,"url":18,"identifiers":831},"Shackford SR, Schmoker JD, Zhuang J (1994) The effect of hypertonic resuscitation on pial arteriolar tone after brain injury and shock. J Trauma 37(6):899–908. https:\u002F\u002Fdoi.org\u002F10.1097\u002F00005373-199412000-00005",{"doi":832},"10.1097\u002F00005373-199412000-00005",{"id":18,"text":834,"url":18,"identifiers":835},"Strandvik GF (2009) Hypertonic saline in critical care: a review of the literature and guidelines for use in hypotensive states and raised intracranial pressure. Anaesthesia 64(9):990–100. https:\u002F\u002Fdoi.org\u002F10.1111\u002Fj.1365-2044.2009.05986.x",{"doi":836},"10.1111\u002Fj.1365-2044.2009.05986.x",{"id":18,"text":838,"url":18,"identifiers":839},"Suarez JI (2004) Hypertonic saline for cerebral edema and elevated intracranial pressure. Cleve Clin J Med 71(Suppl. 1) S9–13. https:\u002F\u002Fdoi.org\u002F10.3949\u002Fccjm.71.suppl-1.s9",{"doi":840},"10.3949\u002Fccjm.71.suppl-1.s9",{"id":18,"text":842,"url":18,"identifiers":843},"Taylor CA, Bell JM, Breiding MJ, Xu L (2017) Traumatic brain injury–related emergency department visits, hospitalizations, and deaths — United States, 2007 and 2013. MMWR Surveill Summ 66(9):1–16. https:\u002F\u002Fdoi.org\u002F10.15585\u002Fmmwr.ss6609a1",{"doi":844},"10.15585\u002Fmmwr.ss6609a1",{"id":18,"text":846,"url":18,"identifiers":847},"Teoh WHL, Westphal M, Kampmeier TG (2014) Update on volume therapy in obstetrics. Best Pract Res Clin Anaesthesiol 28(3):297–303. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.bpa.2014.07.004",{"doi":848},"10.1016\u002Fj.bpa.2014.07.004",{"id":18,"text":850,"url":18,"identifiers":851},"Tyagi R, Donaldson K, Loftus CM, Jallo J (2007) Hypertonic saline: a clinical review. Neurosurg Rev 30(4):277–289; discussion 289-90. https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs10143-007-0091-7",{"doi":852},"10.1007\u002Fs10143-007-0091-7",{"id":18,"text":854,"url":18,"identifiers":855},"Vassar MJ, Perry CA, Holcroft JW (1990) Analysis of potential risks associated with 7.5% sodium chloride resuscitation of traumatic shock. Arch Surg 125:1309–1315. https:\u002F\u002Fdoi.org\u002F10.1001\u002Farchsurg.1990.01410220093013",{"doi":856},"10.1001\u002Farchsurg.1990.01410220093013",{"id":18,"text":858,"url":18,"identifiers":859},"Vialet R, Albanèse J, Thomachot L, Antonini F, Bourgouin A, Alliez B, Martin C (2003) Isovolume hypertonic solutes (sodium chloride or mannitol) in the treatment of refractory posttraumatic intracranial hypertension: 2 ml\u002Fkg 7.5% saline is more effective than 2 ml\u002Fkg 20% mannitol. Crit Care Med 2003 31(6):1683–1687. https:\u002F\u002Fdoi.org\u002F10.1097\u002F01.ccm.0000063268.91710.df",{"doi":860},"10.1097\u002F01.ccm.0000063268.91710.df",{"id":18,"text":862,"url":18,"identifiers":863},"Walsh JC, Zhuang J, Shackford SR (1991) A comparison of hypertonic to isotonic fluid in the resuscitation of brain injury and hemorrhagic shock. J Surg Res 50(3):284–292. https:\u002F\u002Fdoi.org\u002F10.1016\u002F0022-4804(91)90192-O",{"doi":864},"10.1016\u002F0022-4804(91)90192-O",{"id":18,"text":866,"url":18,"identifiers":867},"Wenham TN, Hormis AP, Andrzejowski JC (2008) Hypertonic saline after traumatic brain injury in UK neuro-critical care practice. Anaesthesia 63:558–559. https:\u002F\u002Fdoi.org\u002F10.1111\u002Fj.1365-2044.2008.05532.x",{"doi":868},"10.1111\u002Fj.1365-2044.2008.05532.x",{"id":18,"text":870,"url":18,"identifiers":871},"White H, Cook D, Venkatesh B (2006) The use of hypertonic saline for treating intracranial hypertension after traumatic brain injury. Anesth Anal 102(6):1836–1846. https:\u002F\u002Fdoi.org\u002F10.1213\u002F01.ane.0000217208.51017.56",{"doi":872},"10.1213\u002F01.ane.0000217208.51017.56",{"id":18,"text":874,"url":18,"identifiers":875},"Wu MC, Liao TY, Lee EM, Chen YS, Hsu WT, Lee MG et al (2017) Administration of hypertonic solutions for hemorrhagic shock. Anesth Analg 125(5):1549–1557. https:\u002F\u002Fdoi.org\u002F10.1213\u002FANE.0000000000002451",{"doi":876},"10.1213\u002FANE.0000000000002451",{"id":878,"createTime":879,"updateTime":880,"relativeEntities":881,"slug":882,"properties":883,"entityType":83,"verifyStatus":84,"verifyTime":880,"verifyNote":86,"languages":18,"translateLanguages":18,"viewCount":19,"primaryUrl":894,"fullTextUrl":18,"authors":895,"publicationType":161,"publisherRelationship":950,"citationCount":18,"citationInfo":18,"publishDate":980,"publishYear":981,"citationAnalyzeStatus":17,"lastCitationAnalyze":18,"indexDatabases":982,"openAccess":18,"references":18,"isForceReanalyzing":204},"73add39b-dc41-4a3d-b555-461ee0c852af","2024-04-07T07:37:09.534+00:00","2025-02-27T00:24:20.851+00:00",[],"A-parallel-epidemic-of-sino-nasal-mucormycosis-post-COVID-pneumonia-and-its-anesthetic-implications-a-case-report",{"abstract":884,"title":886,"keywords":888,"references":890,"doi":892},{"EN":885},"There has been a rise in cases of sino-nasal mucormycosis in patients who contracted the COVID-19 virus and were on steroids. Population at risk includes diabetics and on immunosuppressant therapy and\u002For immunocompromised state. Perioperative management becomes challenging due to residual pulmonary disease secondary to COVID pneumonia and complication following systemic antifungal therapy. Such patients often have other associated illnesses like hypertension, obesity, and deranged renal functions, either as a part of metabolic syndrome or post-systemic antifungal therapy. We report a case of a 64-year-old female, a poorly controlled hypertensive, with class 1 obesity, and diabetic on oral hypoglycemic agents, hypothyroid on oral medications, and post-COVID pneumonia with recently diagnosed sino-nasal mucormycosis who was posted for debridement of the sino-nasal fungal mass. The gamut of co-morbid conditions along with post-COVID pneumonia status presents an anesthetic challenge apropos the optimization of the clinical conditions and timing of the surgery considering the emergent nature of the surgery. The timing of operative intervention for such patients is imperative and the treating team of anesthesiologist and the otorhinolaryngologist should aim to strike a balance between timely intervention to negate the spread of the infection to the orbit and brain causing potential irreparable damage and optimizing the cardio-respiratory and renal functions.",{"EN":887},"A parallel epidemic of sino-nasal mucormycosis post-COVID pneumonia, and its anesthetic implications: a case report",{"EN":889},"",{"VOID":891},"Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al (2020) Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 395(10223):507–13. https:\u002F\u002Fdoi.org\u002F10.1016\u002FS0140-6736(20)30211-7. [cited 2021 May 11]\nCornely OA, Alastruey-Izquierdo A, Arenz D, Chen SCA, Dannaoui E, Hochhegger B, et al (2019) Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium. Lancet Infect Dis 19: e405–21. Available from: https:\u002F\u002Fpubmed.ncbi.nlm.nih.gov\u002F31699664\u002F. [cited 2021 May 11].\nGarg D, Muthu V, Sehgal IS, Ramachandran R, Kaur H, Bhalla A, et al (2021) Coronavirus disease (Covid-19) associated mucormycosis (CAM): case report and systematic review of literature. Mycopathologia 186(2). Available from: https:\u002F\u002Fpubmed.ncbi.nlm.nih.gov\u002F33544266\u002F. [cited 2021 May 9].\nPasero D, Sanna S, Liperi C, Piredda D, Branca G Pietro, Casadio L, et al (2020) A challenging complication following SARS-CoV-2 infection: a case of pulmonary mucormycosis. Infection. Available from: https:\u002F\u002Fpubmed.ncbi.nlm.nih.gov\u002F33331988\u002F. [cited 2021 May 9].\nSharma S, Grover M, Bhargava S, Samdani S, Kataria T (2021) Post coronavirus disease mucormycosis: A deadly addition to the pandemic spectrum. J Laryngol Otol 135(5):442–7. https:\u002F\u002Fdoi.org\u002F10.1017\u002Fs0022215121000992.",{"VOID":893},"10.1186\u002Fs42077-023-00327-5","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1186\u002Fs42077-023-00327-5",[896,911,924,937],{"id":897,"sortIndex":19,"researcher":18,"roles":898,"affiliations":899,"properties":908,"displayName":910,"givenName":18,"familyName":18},"ab7cccb8-7789-4f0c-869c-d47d636315c2",[92],[900],{"id":901,"sortIndex":19,"affiliation":902,"properties":18},"683f5e6f-4a0a-476f-95a6-a5d83699f644",{"id":901,"createTime":18,"updateTime":18,"relativeEntities":903,"slug":18,"properties":904,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":907,"statistic":18},[],{"title":905},{"VI":906},"Department of Anaesthesiology, Pain & Critical Care, All India Institute of Medical Sciences, Raipur, India",[],{"title":909},{"VI":910},"Prateek Arora",{"id":912,"sortIndex":58,"researcher":18,"roles":913,"affiliations":914,"properties":921,"displayName":923,"givenName":18,"familyName":18},"9ecfa351-99aa-44ed-a340-7af0ed5cdf54",[92],[915],{"id":901,"sortIndex":19,"affiliation":916,"properties":18},{"id":901,"createTime":18,"updateTime":18,"relativeEntities":917,"slug":18,"properties":918,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":920,"statistic":18},[],{"title":919},{"VI":906},[],{"title":922},{"VI":923},"Abhishek Bharadwaj",{"id":925,"sortIndex":122,"researcher":18,"roles":926,"affiliations":927,"properties":934,"displayName":936,"givenName":18,"familyName":18},"4e1c76ec-4a54-4bd8-a6af-895b009ae9ec",[92],[928],{"id":901,"sortIndex":19,"affiliation":929,"properties":18},{"id":901,"createTime":18,"updateTime":18,"relativeEntities":930,"slug":18,"properties":931,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":933,"statistic":18},[],{"title":932},{"VI":906},[],{"title":935},{"VI":936},"Omer Mohammed Mujahid",{"id":938,"sortIndex":56,"researcher":18,"roles":939,"affiliations":940,"properties":947,"displayName":949,"givenName":18,"familyName":18},"0c2f2bfe-9475-4767-ba5b-c6a8536af279",[92],[941],{"id":901,"sortIndex":19,"affiliation":942,"properties":18},{"id":901,"createTime":18,"updateTime":18,"relativeEntities":943,"slug":18,"properties":944,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":946,"statistic":18},[],{"title":945},{"VI":906},[],{"title":948},{"VI":949},"Monica Khetarpal",{"url":18,"publisher":951,"properties":18},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":952,"slug":10,"properties":953,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":956,"manageAffiliations":961,"indexDatabases":967,"url":53,"thumbnailPath":18,"statistic":975,"gsStatistic":18,"type":61,"analyzePriority":18},[],{"issn":954,"title":955},{"VOID":13},{"EN":15},[957],{"id":22,"createTime":18,"updateTime":18,"relativeEntities":958,"label":959,"description":960,"parentId":18,"standard":18,"scholarHubFieldId":18},[],{"EN":25},{},[962],{"id":29,"createTime":18,"updateTime":18,"relativeEntities":963,"slug":18,"properties":964,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":966,"statistic":18},[],{"title":965},{"EN":33},[],[968],{"id":37,"indexDatabase":969,"url":50,"indexYears":18,"academicFieldIds":974,"indexDatabaseRanking":18},{"id":39,"createTime":18,"updateTime":18,"relativeEntities":970,"label":971,"description":972,"key":46,"publicationTags":973,"standard":18},[],{"EN":42,"VI":42},{"EN":44,"VI":45},[48,49],[52],{"impactFactor":19,"impactFactorByYear":976,"i10Index":19,"i10IndexLast5Year":19,"totalPublication":56,"totalPublicationByYear":977,"totalCitation":19,"totalCitationByYear":978,"totalCitationPerPublication":19,"totalCitationPerPublicationByYear":979,"hindexLast5Year":19,"hindex":19},{},{"2019":58,"2020":58,"2022":58},{},{},"2023-05-16",2023,[48],{"id":984,"createTime":985,"updateTime":986,"relativeEntities":987,"slug":988,"properties":989,"entityType":83,"verifyStatus":84,"verifyTime":998,"verifyNote":86,"languages":18,"translateLanguages":18,"viewCount":19,"primaryUrl":999,"fullTextUrl":18,"authors":1000,"publicationType":161,"publisherRelationship":1088,"citationCount":18,"citationInfo":18,"publishDate":1123,"publishYear":981,"citationAnalyzeStatus":17,"lastCitationAnalyze":18,"indexDatabases":1124,"openAccess":18,"references":18,"isForceReanalyzing":204},"bb7915fd-b193-445e-b4d0-aa1deea159bd","2024-02-09T07:44:50.239+00:00","2025-02-26T05:26:53.307+00:00",[],"The-efficacy-and-safety-of-perioperative-administration-of-dexamethasone-a-systematic-review-and-meta-analysis",{"abstract":990,"title":992,"references":994,"doi":996},{"EN":991},"Perioperative prophylactic dexamethasone is commonly administered to reduce postoperative nausea and vomiting (PONV) and pain after surgery. In this study, we aimed to systematically review the efficacy and adverse effects of perioperative dexamethasone administration. We conducted a systematic search until January 2023 in scientific databases, including PubMed, Scopus, Embase, Web of Science, and Google Scholar. After assessing the methodological quality of relevant studies, we synthesized those focusing on PONV, oral food intake tolerance, impaired wound healing, major postoperative complications, and postoperative infections following the perioperative administration of dexamethasone. A total of 27 studies were included in this systematic review and meta-analysis. The dexamethasone group showed decreased PONV (OR = 0.19; 95% CI 0.06–0.55), increased oral food intake tolerance (OR = 7.38; 95% CI 1.07–51.11), increased risk of impaired wound healing (OR = .48; 95% CI 0.52–4.21), decreased probability of postoperative infection (OR = 0.61; 95% CI 0.51–0.72), and increased risk of major postoperative complications (OR = 1.27; 95% CI 0.68–2.39) compared to the controls. The results of our pooled data analysis showed that dexamethasone was superior to the control in terms of PONV, oral food intake tolerance, and postoperative infections.",{"EN":993},"The efficacy and safety of perioperative administration of dexamethasone: a systematic review and meta-analysis",{"VOID":995},"Apfel C, Kranke P, Eberhart L (2004) Comparison of surgical site and patient’s history with a simplified risk score for the prediction of postoperative nausea and vomiting. Anaesthesia 59(11):1078–1082\nBackes JR, Bentley JC, Politi JR, Chambers BT (2013) Dexamethasone reduces length of hospitalization and improves postoperative pain and nausea after total joint arthroplasty: a prospective, randomized controlled trial. J Arthroplasty 28(8):11–17\nBahammam MA, Kayal RA, Alasmari DS, Attia MS, Bahammam LA, Hassan MH et al (2017) Comparison between dexamethasone and ibuprofen for postoperative pain prevention and control after surgical implant placement: a double-masked, parallel-group, placebo-controlled randomized clinical trial. J Periodontol 88(1):69–77\nBartlett R, Hartle AJ (2013) Routine use of dexamethasone for postoperative nausea and vomiting: the case against. Anaesthesia. 68(9):892–6\nBateman MC, Conejero JA, Mooney EK, Rothkopf DM (2006) Short-stay cleft palate surgery with intraoperative dexamethasone and marcaine. Ann Plast Surg. 57(3):245–7\nBlume C, Wiederhold H, Geiger M, Clusmann H, Müller CA (2018a) Lacking benefit of intraoperative high-dose dexamethasone in instrumented surgery for cervical Spondylotic myelopathy. J Neurol Surg A Central Eur Neurosurg 79(02):116–122\nBlume C, Wiederhold H, Geiger M, Clusmann H, Müller CA (2018b) Lacking Benefit of Intraoperative High-Dose Dexamethasone in Instrumented Surgery for Cervical Spondylotic Myelopathy. J Neurol Surg A Cent Eur Neurosurg 79(02):116–122\nChen CC, Siddiqui FJ, Chen TL, Chan ESY, Tam KW (2012) Dexamethasone for prevention of postoperative nausea and vomiting in patients undergoing thyroidectomy: meta-analysis of randomized controlled trials. World J Surg. 36(1):61–8\nCorcoran T, Kasza J, Short T, O’loughlin E, Chan M, Leslie K et al (2017) Intraoperative dexamethasone does not increase the risk of postoperative wound infection: a propensity score-matched post hoc analysis of the ENIGMA-II trial (EnDEX). Br J Anaesthesia. 118(2):190–9\nCorcoran T, Kasza J, Short T, Oloughlin E, Chan M, Leslie K et al (2017) Intraoperative dexamethasone does not increase the risk of postoperative wound infection: a propensity score-matched post hoc analysis of the ENIGMA-II trial (EnDEX). Br J Anaesth. 118(2):190–9\nCui Z, Liu X, Teng Y, Jiang J, Wang J, Xia Y (2015) The efficacy of steroid injection in total knee or hip arthroplasty. Knee Surg Sports Traumatol Arthrosc 23(8):2306–2314\nDan AE, Thygesen TH, Pinholt EM (2010) Corticosteroid administration in oral and orthognathic surgery: a systematic review of the literature and meta-analysis. J Oral Maxillofac Surg 68(9):2207–2220\nDieleman JM, Nierich AP, Rosseel PM, van der Maaten JM, Hofland J, Diephuis JC et al (2012) Intraoperative High-Dose Dexamethasone for Cardiac Surgery: a Randomized Controlled Trial. JAMA 308(17):1761–1767\nEgan KG, Allen A, Hendren G, Mellott AJ, Bhavsar D (2019a) Effects of intraoperative dexamethasone administration in adult diabetic burn patients. J Burn Care Res 40(5):627–632\nEgan KG, Allen A, Hendren G, Mellott AJ, Bhavsar D (2019b) Effects of intraoperative dexamethasone administration in adult diabetic burn patients. J Burn Care Res 40(5):627–632\nEriksen T, Lassen C, Gögenur I (2014) Treatment with corticosteroids and the risk of anastomotic leakage following lower gastrointestinal surgery: a literature survey. Colorectal Dis 16(5):O154–O160\nFan Z-r, Ma J, Ma X-l, Wang Y, Sun L, Wang Y, et al (2018) The efficacy of dexamethasone on pain and recovery after total hip arthroplasty: A systematic review and meta-analysis of randomized controlled trials. Medicine. 97(13):e0100\nFoulkes G, Robinson Jr JJ (1990) Intraoperative Dexamethasone Irrigation in Lumbar Microdiskectomy. Clin Orthop Relat Res 261:224–228\nGan TJ, Meyer TA, Apfel CC, Chung F, Davis PJ, Habib AS et al (2007) Society for Ambulatory Anesthesia guidelines for the management of postoperative nausea and vomiting. Anesth Analg 105(6):1615–1628\nHatfield S (2017) The association between intraoperative single-dose dexamethasone and postoperative pain in patients undergoing laparoscopic cholecystectomy\nItuk U, Thenuwara K (2018) The effect of a single intraoperative dose of intravenous dexamethasone 8 mg on post-cesarean delivery analgesia: a randomized controlled trial. Int J Obstet Anesth 35:57–63\nJacob KA, Leaf DE, Dieleman JM, Van Dijk D, Nierich AP, Rosseel PM et al (2015a) Intraoperative High-Dose Dexamethasone and Severe AKI after Cardiac Surgery. J Am Soc Nephrol 26(12):2947–2951\nJacob KA, Dieleman JM, Nathoe HM, van Osch D, de Waal EE, Cramer MJ et al (2015b) The Effects of Intraoperative Dexamethasone on Left Atrial Function and Postoperative Atrial Fibrillation in Cardiac Surgical Patients. Neth Heart J 23(3):168–173\nJolley S (2001) Managing post-operative nausea and vomiting. Nursing Standard (through 2013). 15(40):47\nJules-Elysee KM, Lipnitsky JY, Patel N, Anastasian G, Wilfred SE, Urban MK et al (2011) Use of low-dose steroids in decreasing cytokine release during bilateral total knee replacement. Regional Anesthesia Pain Med. 36(1):36–40\nKaraman M, İlhan AE, Dereci G, Arman T (2009a) Determination of optimum dosage of intraoperative single dose dexamethasone in pediatric tonsillectomy and adenotonsillectomy. Int J Pediatr Otorhinolaryngol 73(11):1513–1515\nKaraman M, İlhan AE, Dereci G, Tek A (2009b) Determination of optimum dosage of intraoperative single dose dexamethasone in pediatric tonsillectomy and adenotonsillectomy. Int J Pediatr Otorhinolaryngol 73(11):1513–1515\nKhan MI, Iqbal MK (2012) Post Tonsillectomy pain: Role of single intraoperative dose of Dexamethasone. Pakistan J Med Health Scie Online http:\u002F\u002Fpjmhsonline.com\u002FJuly-Sept\nKleif J, Kirkegaard A, Vilandt J, Gögenur I (2017) Randomized clinical trial of preoperative dexamethasone on postoperative nausea and vomiting after laparoscopy for suspected appendicitis. J Br Surg 104(4):384–392\nKlement MR, Wilkens HS, Fillingham YA, Manrique J, Austin MS, Parvizi J (2018) Intraoperative dexamethasone reduces readmission rates without affecting risk of thromboembolic events or infection after total joint arthroplasty. J Arthroplasty. 33(10):3252–6\nKwon S, Thompson R, Dellinger P, Yanez D, Farrohki E, Flum D (2013) Importance of perioperative glycemic control in general surgery: a report from the Surgical Care and Outcomes Assessment Program. Ann Surg 257(1):8\nLim SH, Jang EH, Kim M-H, Cho K, Lee JH, Lee KM et al (2011) Analgesic Effect of Preoperative versus Intraoperative Dexamethasone after Laparoscopic Cholecystectomy with Multimodal Analgesia. Korean J Anesthesiol 61(4):315\nLomivorotov V, Kornilov I, Boboshko V, Shmyrev V, Bondarenko I, Soynov I et al (2020) Effect of intraoperative dexamethasone on major complications and mortality among infants undergoing cardiac surgery: the DECISION randomized clinical trial. JAMA. 323(24):2485–92\nLunn T, Kehlet H (2013) Perioperative glucocorticoids in hip and knee surgery–benefit vs. harm? A review of randomized clinical trials. Acta Anaesthesiologica Scandinavica. 57(7):823–34\nNewhook TE, Soliz JM, Prakash LR, Hancher-Hodges S, Speer BB, Wilks JA et al (2021a) Impact of intraoperative dexamethasone on surgical and oncologic outcomes for patients with resected pancreatic ductal adenocarcinoma. Ann Surg Oncol 28(3):1563–1569\nNewhook TE, Soliz JM, Prakash LR, Hancher-Hodges S, Speer BB, Wilks JA et al (2021b) Impact of Intraoperative Dexamethasone on Surgical and Oncologic Outcomes for Patients with Resected Pancreatic Ductal Adenocarcinoma. Ann Surg Oncol 28(3):1563–1569\nPappas A, Sukhani R, Hotaling A, Mikat-Stevens M, Donzelli J, Shenoy K (1998) The effect of intraoperative dexamethasone on the immediate and delayed postoperative morbidity in children undergoing ambulatory adenotonsillectomy. Anesth Analg 86(2S):14S\nPappas A, Sukhani R, Hotaling A, Mikat-Stevens M, Donzelli J, Shenoy K (1998) The effect of intraoperative dexamethasone on the immediate and delayed postoperative morbidity in children undergoing ambulatory adenotonsillectomy. Anesth Analg 86(2S):14S\nPolderman JA, Farhang-Razi V, Van Dieren S, Kranke P, DeVries JH, Hollmann MW et al (2018) Adverse side effects of dexamethasone in surgical patients. Cochrane Database Syst Rev. 8(8):CD01940-CD\nSamona J, Cook C, Krupa K, Swatsell K, Jackson A, Dukes C et al (2017) Effect of Intraoperative Dexamethasone on Pain Scores and Narcotic Consumption in Patients Undergoing Total Knee Arthroplasty. Orthop Surg 9(1):110–114\nSandini M, Ruscic KJ, Ferrone CR, Warshaw AL, Qadan M, Eikermann M et al (2018a) Intraoperative dexamethasone decreases infectious complications after pancreaticoduodenectomy and is associated with long-term survival in pancreatic cancer. Ann Surg Oncol 25(13):4020–4026\nSandini M, Ruscic KJ, Ferrone CR, Warshaw AL, Qadan M, Eikermann M et al (2018b) Intraoperative Dexamethasone Decreases Infectious Complications after Pancreaticoduodenectomy and is Associated with Long-Term Survival in Pancreatic Cancer. Ann Surg Oncol 25(13):4020–4026\nSauër AMC, Slooter AJ, Veldhuijzen DS, van Eijk MM, Devlin JW, van Dijk DJA et al (2014) Intraoperative dexamethasone and delirium after cardiac surgery: a randomized clinical trial. Anesth Analg. 119(5):1046–52\nSchimmer BP, Funder JW (2011) ACTH, adrenal steroids, and pharmacology of the adrenal cortex. Goodman and Gilman’s the pharmacological basis of therapeutics. pp 1209–36\nShakeel M, Trinidade A, Al-Adhami A, Karamchandani D, Engelhardt T, Ah-See KW et al (2010) Intraoperative Dexamethasone and the Risk of Secondary Posttonsillectomy Hemorrhage. J Otolaryngol Head Neck Surg 39(6):732–736\nSnäll J, Kormi E, Lindqvist C, Suominen AL, Mesimäki K, Törnwall J et al (2013) Impairment of wound healing after operative treatment of mandibular fractures, and the influence of dexamethasone. Br J Oral Maxillofac Surg 51(8):808–812\nSplinter WM, Roberts DJ (1996) Dexamethasone decreases vomiting by children after tonsillectomy. Anesth Analg 83(5):913–916\nThongrong C, Chullabodhi P, Kasemsiri P, Kitkhuandee A, Plailaharn N, Sabangban L, et al (2018) Effects of intraoperative dexamethasone and ondansetron on postoperative nausea and vomiting in microvascular decompression surgery: a randomized controlled study. 2018\nTkachenko R, Pyasetska N (2019) The efficiency of intrathecal dexamethasone for spinal anaesthesia in elective caesarean section. Regional Anesthesia Pain Med. 44(10):A192-A\nVan Osch D, Dieleman JM, Nathoe HM, Boasson MP, Kluin J, Bunge JJ et al (2015) Intraoperative High-Dose Dexamethasone in Cardiac Surgery and the Risk of Rethoracotomy. Ann Thorac Surg 100(6):2237–2242\nXu L, Xie X, Gu X (2020) Dexamethasone for preventing postoperative nausea and vomiting after mastectomy. Medicine 99(30):e21417\nZhang H, Lu J, Wu Q, Wu B, Xu C, Fan Y et al (2019) A perioperative small dose of dexamethasone enhances postoperative recovery by reducing volume and inflammatory contents in wound drainage after thyroid surgery: a double-blinded, randomized, prospective study. World J Surg 43(7):1721–1727",{"VOID":997},"10.1186\u002Fs42077-023-00376-w","2025-02-26T05:26:53.306+00:00","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1186\u002Fs42077-023-00376-w",[1001,1016,1029,1042,1057,1072],{"id":1002,"sortIndex":19,"researcher":18,"roles":1003,"affiliations":1004,"properties":1013,"displayName":1015,"givenName":18,"familyName":18},"8a4cc399-4cca-44f8-a4f0-2085518cb279",[92],[1005],{"id":1006,"sortIndex":19,"affiliation":1007,"properties":18},"f64cee71-4ecb-44f7-8e71-2401e10db04a",{"id":1006,"createTime":18,"updateTime":18,"relativeEntities":1008,"slug":18,"properties":1009,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":1012,"statistic":18},[],{"title":1010},{"VI":1011},"Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran",[],{"title":1014},{"VI":1015},"Mohammad Javad 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Hashemian",{"url":999,"publisher":1089,"properties":1118},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1090,"slug":10,"properties":1091,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":1094,"manageAffiliations":1099,"indexDatabases":1105,"url":53,"thumbnailPath":18,"statistic":1113,"gsStatistic":18,"type":61,"analyzePriority":18},[],{"issn":1092,"title":1093},{"VOID":13},{"EN":15},[1095],{"id":22,"createTime":18,"updateTime":18,"relativeEntities":1096,"label":1097,"description":1098,"parentId":18,"standard":18,"scholarHubFieldId":18},[],{"EN":25},{},[1100],{"id":29,"createTime":18,"updateTime":18,"relativeEntities":1101,"slug":18,"properties":1102,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":1104,"statistic":18},[],{"title":1103},{"EN":33},[],[1106],{"id":37,"indexDatabase":1107,"url":50,"indexYears":18,"academicFieldIds":1112,"indexDatabaseRanking":18},{"id":39,"createTime":18,"updateTime":18,"relativeEntities":1108,"label":1109,"description":1110,"key":46,"publicationTags":1111,"standard":18},[],{"EN":42,"VI":42},{"EN":44,"VI":45},[48,49],[52],{"impactFactor":19,"impactFactorByYear":1114,"i10Index":19,"i10IndexLast5Year":19,"totalPublication":56,"totalPublicationByYear":1115,"totalCitation":19,"totalCitationByYear":1116,"totalCitationPerPublication":19,"totalCitationPerPublicationByYear":1117,"hindexLast5Year":19,"hindex":19},{},{"2019":58,"2020":58,"2022":58},{},{},{"pages":1119,"volume":1121},{"VOID":1120},"1-12",{"VOID":1122},"15","2023-10-02",[48],{"id":1126,"createTime":1127,"updateTime":1128,"relativeEntities":1129,"slug":1130,"properties":1131,"entityType":83,"verifyStatus":84,"verifyTime":1128,"verifyNote":86,"languages":18,"translateLanguages":18,"viewCount":19,"primaryUrl":1140,"fullTextUrl":18,"authors":1141,"publicationType":161,"publisherRelationship":1185,"citationCount":18,"citationInfo":18,"publishDate":1218,"publishYear":198,"citationAnalyzeStatus":17,"lastCitationAnalyze":18,"indexDatabases":1219,"openAccess":18,"references":18,"isForceReanalyzing":204},"549dbc07-19d4-46f4-b4b2-eff7c0cc56a8","2024-01-17T08:12:49.351+00:00","2025-02-26T01:43:46.401+00:00",[],"Nerve-block-using-local-anesthetic-and-dexmedetomidine-in-patients-undergoing-functional-endoscopic-sinus-surgery",{"abstract":1132,"title":1134,"references":1136,"doi":1138},{"EN":1133},"The main anesthetic goal in the postoperative period of functional endoscopic sinus surgery (FESS) is early and pain-free recovery, with return of protective airway reflex. The aim of this study is to evaluate the role of dexmedetomidine as an adjuvant to regional blocks in patients undergoing functional endoscopic sinus surgery. Group bupivacaine + dexmedetomidine (BD) showed statistically significantly lower postoperative pain measurements than group bupivacaine (B), longer time to the first request of rescue analgesia, less patients needing rescue analgesia, and less rescue morphine analgesic requirements. Other measurements were insignificantly different between both groups. Dexmedetomidine can be used as an adjuvant to regional nerve block in patients undergoing functional endoscopic sinus surgery. It effectively prolonged postoperative analgesia, decreased postoperative opioid analgesic requirements, and reduced the number of patients needing rescue analgesia.",{"EN":1135},"Nerve block using local anesthetic and dexmedetomidine in patients undergoing functional endoscopic sinus surgery",{"VOID":1137},"Almarakbi WA, Kaki AM (2014) Addition of dexmedetomidine to bupivacaine in transversus abdominis plane block potentiates post-operative pain relief among abdominal hysterectomy patients: a prospective randomized controlled trial. Saudi J Anaesth 8(2):161–166\nBhattacharyya S, Tewari MK, Ghosh S et al (2016) Evaluation of the efficacy of bilateral sphenopalatine ganglion block in endoscopic sinus surgery under general anesthesia: a randomized prospective controlled trial. Rese Opin Anesth Intensive Care 3(4):173–178\nBoezaart AP, van der Merwe J, Coetzee A (1995) Comparison of sodium nitroprusside-and esmolol-induced controlled hypotension for functional endoscopic sinus surgery. 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Saudi J Anaesth 10(1):18–24\nHigashizawa T, Koga Y (2001) Effect of infraorbital nerve block under general anesthesia on consumption of isoflurane and postoperative pain in endoscopic endonasal maxillary sinus surgery. J Anesth 15(3):136–138\nHussain N, Brummett CM, Brull R et al (2021) Efficacy of perineural versus intravenous dexmedetomidine as a peripheral nerve block adjunct: a systematic review. Reg Anesth Pain Med 46:704–712\nHussain N, Grzywacz VP, Ferreri CA et al (2017) Investigating the efficacy of dexmedetomidine as an adjuvant to local anesthesia in brachial plexus block: a systematic review and meta-analysis of 18 randomized controlled trials. Reg Anesth Pain Med 42(2):184–196\nKandinov A, Nguyen BK, Yuhan BT et al (2021) Evidence-based perioperative analgesia for otolaryngology: head and neck surgery. In: Perioperative pain control: tools for surgeons. Springer, Cham, pp 175–206\nKempen P (2012) Anesthesia for endoscopic sinus surgery. In: Abdelmalak B, Doyle J (eds) Anesthesia for Otolaryngologic Surgery. Cambridge University Press, Cambridge, pp 121–132. https:\u002F\u002Fdoi.org\u002F10.1017\u002FCBO9781139088312.016\nKim HS, Lee HK, Jeong HS et al (2013) Decreased postoperative pain after reduction of fractured nasal bones using a nerve block of the anterior ethmoidal nerve. Int J Oral MaxillofacSurg 42(6):727–731\nLönnqvist PA (2012) Alpha-2 adrenoceptor agonists as adjuncts to peripheral nerve blocks in children--is there a mechanism of action and should we use them? PaediatrAnaesth. 22(5):421–424\nMarhofer D, Kettner SC, Marhofer P et al (2013) Dexmedetomidine as an adjuvant to ropivacaine prolongs peripheral nerve block: a volunteer study. Br J Anaesth 110(3):438–442\nObayah GM, Refaie A, Aboushanab O et al (2010) Addition of dexmedetomidine to bupivacaine for greater palatine nerve block prolongs postoperative analgesia after cleft palate repair. EJA 27(3):280–284\nOwais Amin I, Mohammad Abdalla A, Abdalla Al-Kumity A et al (2020) Combined regional nasal block and general anesthesia versus general anesthesia with induced hypotension technique during endoscopic sinus surgery. Al-Azhar Med J 49(1):1–4\nPaudel D, Chettri ST, Shah SP et al (2018) The effect of pterygopalatine fossa block (PPFB) during endoscopic sinus surgery (ESS) on intraoperative bleeding: a randomized control trial. J BP Koirala Institute Health Sci 1(2):35–41\nPrabhakar A, Lambert T, Kaye RJ et al (2019) Adjuvants in clinical regional anesthesia practice: a comprehensive review. Best Pract Res Clin Anaesthesiol 33(4):415–423\nRancourt MP, Albert NT, Côté M et al (2012) Posterior tibial nerve sensory blockade duration prolonged by adding dexmedetomidine to ropivacaine. Anesth Analg 115(4):958–962\nRao S, Rajan N (2021) Dexmedetomidine as an adjunct for regional anesthetic nerve blocks. Curr Pain Headache Rep 25(2):1–7\nShamil E, Casselden E, Bast F et al (2018) Role of local anaesthetic nerve block in patients undergoing endonasal surgery–our experience of 48 patients. Rhinology Online 1:90–93",{"VOID":1139},"10.1186\u002Fs42077-022-00247-w","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1186\u002Fs42077-022-00247-w",[1142,1157,1172],{"id":1143,"sortIndex":19,"researcher":18,"roles":1144,"affiliations":1145,"properties":1154,"displayName":1156,"givenName":18,"familyName":18},"665239eb-03a4-485b-a964-6e583fcfcd38",[92],[1146],{"id":1147,"sortIndex":19,"affiliation":1148,"properties":18},"2f62c262-b8a2-4b09-abab-fd229570310b",{"id":1147,"createTime":18,"updateTime":18,"relativeEntities":1149,"slug":18,"properties":1150,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":1153,"statistic":18},[],{"title":1151},{"VI":1152},"Anesthesiology, Surgical Intensive Care & Pain Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt",[],{"title":1155},{"VI":1156},"Tarek Abdel hay Mostafa",{"id":1158,"sortIndex":58,"researcher":18,"roles":1159,"affiliations":1160,"properties":1169,"displayName":1171,"givenName":18,"familyName":18},"e16dd712-7dd8-422c-b77d-57fced48971f",[92],[1161],{"id":1162,"sortIndex":19,"affiliation":1163,"properties":18},"0c576149-5c7b-40e9-9207-12ddadd0c15e",{"id":1162,"createTime":18,"updateTime":18,"relativeEntities":1164,"slug":18,"properties":1165,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":1168,"statistic":18},[],{"title":1166},{"EN":1167},"Otorhinolaryngology Department, Faculty of Medicine, Tanta University, Tanta, Egypt",[],{"title":1170},{"VI":1171},"Mohammed Osama Tommom",{"id":1173,"sortIndex":122,"researcher":18,"roles":1174,"affiliations":1175,"properties":1182,"displayName":1184,"givenName":18,"familyName":18},"f7cd05ad-02ed-4b6f-8484-c6474d664ce8",[92],[1176],{"id":1147,"sortIndex":19,"affiliation":1177,"properties":18},{"id":1147,"createTime":18,"updateTime":18,"relativeEntities":1178,"slug":18,"properties":1179,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":1181,"statistic":18},[],{"title":1180},{"VI":1152},[],{"title":1183},{"VI":1184},"Naglaa Khalil Khalil",{"url":1140,"publisher":1186,"properties":1215},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1187,"slug":10,"properties":1188,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":1191,"manageAffiliations":1196,"indexDatabases":1202,"url":53,"thumbnailPath":18,"statistic":1210,"gsStatistic":18,"type":61,"analyzePriority":18},[],{"issn":1189,"title":1190},{"VOID":13},{"EN":15},[1192],{"id":22,"createTime":18,"updateTime":18,"relativeEntities":1193,"label":1194,"description":1195,"parentId":18,"standard":18,"scholarHubFieldId":18},[],{"EN":25},{},[1197],{"id":29,"createTime":18,"updateTime":18,"relativeEntities":1198,"slug":18,"properties":1199,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":1201,"statistic":18},[],{"title":1200},{"EN":33},[],[1203],{"id":37,"indexDatabase":1204,"url":50,"indexYears":18,"academicFieldIds":1209,"indexDatabaseRanking":18},{"id":39,"createTime":18,"updateTime":18,"relativeEntities":1205,"label":1206,"description":1207,"key":46,"publicationTags":1208,"standard":18},[],{"EN":42,"VI":42},{"EN":44,"VI":45},[48,49],[52],{"impactFactor":19,"impactFactorByYear":1211,"i10Index":19,"i10IndexLast5Year":19,"totalPublication":56,"totalPublicationByYear":1212,"totalCitation":19,"totalCitationByYear":1213,"totalCitationPerPublication":19,"totalCitationPerPublicationByYear":1214,"hindexLast5Year":19,"hindex":19},{},{"2019":58,"2020":58,"2022":58},{},{},{"pages":1216,"volume":1217},{"VOID":194},{"VOID":196},"2022-05-20",[48],{"id":1221,"createTime":1222,"updateTime":1223,"relativeEntities":1224,"slug":1225,"properties":1226,"entityType":83,"verifyStatus":84,"verifyTime":1223,"verifyNote":86,"languages":18,"translateLanguages":18,"viewCount":19,"primaryUrl":1235,"fullTextUrl":18,"authors":1236,"publicationType":161,"publisherRelationship":1278,"citationCount":18,"citationInfo":18,"publishDate":1313,"publishYear":1314,"citationAnalyzeStatus":17,"lastCitationAnalyze":18,"indexDatabases":1315,"openAccess":18,"references":18,"isForceReanalyzing":204},"381f9831-5755-469b-b486-5a2c72b4901d","2023-12-11T23:57:31.920+00:00","2025-02-25T15:04:21.235+00:00",[],"Terlipressin-infusion-for-prevention-of-vasoplegic-syndrome-in-patients-treated-with-angiotensin-II-receptor-antagonist-undergoing-coronary-artery-bypass-graft-surgery-a-randomized-controlled-study",{"abstract":1227,"title":1229,"references":1231,"doi":1233},{"EN":1228},"Preoperative use of renin angiotensin system antagonists has been considered an independent risk factor for development of vasoplegic syndrome. The aim of this study was to demonstrate efficacy of prophylactic terlipressin infusion for prevention of vasoplegic syndrome in patients treated with angiotensin receptor blocker undergoing coronary artery bypass graft surgery. One hundred patients on angiotensin II receptor antagonist [losartan] scheduled for coronary artery bypass surgery were enrolled into this prospective randomized controlled study. Anesthetic technique, surgical technique, and cardiopulmonary bypass management were standardized for all patients. With the start of rewarming, patients were randomized to receive either terlipressin infusion 1.3 μg.kg−1.hour−1, or normal saline infusion. Incidence of vasoplegic syndrome score was used as primary outcome. Hemodynamic parameters, inotropic score, and vasopressor dependency index were used as secondary outcome. Incidence of vasoplegic syndrome was significantly lower in terlipressin group compared to placebo group. Norepinephrine was required in 2 patients of terlipressin versus 15 patients of placebo group. Mean arterial blood pressure was significantly higher in terlipressin group compared to placebo group (81.7 ± 18.5 versus 69.3 ± 20.2 at 60 min after weaning from CBP). Cardiac index was significantly lower in terlipressin group compared to placebo group (2.52 ± 1.48 versus 3.2 ± 1.55). Systemic vascular resistance was significantly higher in terlipressin group compared to placebo group (2438.09 ± 735.13 versus 1575.05 ± 753.54). Inotropic score and vasopressor dependency index were significantly lower in terlipressin group compared to placebo group. Prophylactic terlipressin infusion could prevent development of vasoplegic syndrome in patients treated with angiotensin II receptor antagonist undergoing coronary artery bypass graft surgery. PACTR, PACTR201804003249274, Registered 25\u002F03\u002F2018—retrospectively registered, https:\u002F\u002Fpactr.samrc.ac.za\u002FTrialDisplay.aspx?TrialID=3249.",{"EN":1230},"Terlipressin infusion for prevention of vasoplegic syndrome in patients treated with angiotensin II receptor antagonist undergoing coronary artery bypass graft surgery: a randomized controlled study",{"VOID":1232},"Ang CH, Koo OT, Howe TS (2015) Four limb amputations due to peripheral gangrene from inotrope use - Case report and review of the literature. Int J Surg Case Rep 14:63–65\nArgenziano M, Chen JM, Choudhri AF, Cullinane S, Garfein E, Weinberg AD, Smith CR Jr, Rose EA, Landry DW, Oz MC (1998) Management of vasodilatory shock after cardiac surgery: identification of predisposing factors and use of a novel pressor agent. J Thorac Cardiovasc Surg 116(6):973–980\nBenit E, Vranckx P, Jaspers L, Jackmaert R, Poelmans C, Coninx R (1996) Frequency of a positive modified Allen's test in 1,000 consecutive patients undergoing cardiac catheterization. Cathet Cardiovasc Diagn 38(4):352–354\nBirnbaumer M (2000) Vasopressin receptors. Trends Endocrinol Metab 11(10):406–410\nBoccara G, Ouattara A, Godet G, Dufresne E, Bertrand M, Riou B, Coriat P (2003) Terlipressin versus norepinephrine to correct refractory arterial hypotension after general anesthesia in patients chronically treated with renin-angiotensin system inhibitors. Anesthesiology 98(6):1338–1344\nCardoso de Castro LU, Ida KK, Otsuki DA, Sanches TR, Volpini RA, EDS B, Malbouisson LS, Andrade L (2016) Vasopressin analog terlipressin attenuates kidney injury in hemorrhagic shock. Trauma Surg Acute Care Open 1(1):e000039\nColson PH, Bernard C, Struck J, Morgenthaler NG, Albat B, Guillon G (2011) Post cardiac surgery vasoplegia is associated with high preoperative copeptin plasma concentration. Critical Care 15(5):R255\nCruz DN, Antonelli M, Fumagalli R, Foltran F, Brienza N, Donati A, Malcangi V, Petrini F, Volta G, Bobbio Pallavicini FM et al (2009) Early use of polymyxin B hemoperfusion in abdominal septic shock: the EUPHAS randomized controlled trial. JAMA 301(23):2445–2452\nFabrizi F, Dixit V, Messa P, Martin P (2009) Terlipressin for hepatorenal syndrome: A meta-analysis of randomized trials. Int J Artif Organs 32(3):133–140\nFischer GW, Levin MA (2010) Vasoplegia during cardiac surgery: current concepts and management. Semin Thorac Cardiovasc Surg 22(2):140–144\nHasija S, Makhija N, Choudhury M, Hote M, Chauhan S, Kiran U (2010) Prophylactic vasopressin in patients receiving the angiotensin-converting enzyme inhibitor ramipril undergoing coronary artery bypass graft surgery. J Cardiothorac Vasc Anesth 24(2):230–238\nKrag A, Bendtsen F, Mortensen C, Henriksen JH, Moller S (2010) Effects of a single terlipressin administration on cardiac function and perfusion in cirrhosis. Eur J Gastroenterol Hepatol 22(9):1085–1092\nKrag A, Moller S, Henriksen JH, Holstein-Rathlou NH, Larsen FS, Bendtsen F (2007) Terlipressin improves renal function in patients with cirrhosis and ascites without hepatorenal syndrome. Hepatology 46(6):1863–1871\nKunstyr J, Lincova D, Mourad M, Lips M, Cermak T, Kotulak T, Blaha J, Rubes D, Matias M, Stritesky M (2008) A retrospective analysis of Terlipressin infusion in patients with refractory hypotension after cardiac surgery. J Cardiovasc Surg (Torino) 49(3):381–387\nMa TK, Kam KK, Yan BP, Lam YY (2010) Renin-angiotensin-aldosterone system blockade for cardiovascular diseases: current status. Br J Pharmacol 160(6):1273–1292\nMatsukuma S, Sakamoto K, Nishiyama M, Tamesa T, Yoshino S, Hazama S, Oshibuchi R, Matsuda N, Matsumoto S, Wakamatsu H et al (2015) Prognostic factors in patients with septic shock in digestive surgery who have undergone direct hemoperfusion with polymyxin B-immobilized fibers: a retrospective observational study. J Intensive Care 3:13\nMaybauer MO, Maybauer DM, Enkhbaatar P, Traber DL (2008) Physiology of the vasopressin receptors. Best Practice & Research Clinical Anaesthesiology 22(2):253–263\nMekontso-Dessap A, Houel R, Soustelle C, Kirsch M, Thebert D, Loisance DY (2001) Risk factors for post-cardiopulmonary bypass vasoplegia in patients with preserved left ventricular function. Ann Thorac Surg 71(5):1428–1432\nMorales DL, Garrido MJ, Madigan JD, Helman DN, Faber J, Williams MR, Landry DW, Oz MC (2003) A double-blind randomized trial: prophylactic vasopressin reduces hypotension after cardiopulmonary bypass. Ann Thorac Surg 75(3):926–930\nMorelli A, Ertmer C, Pietropaoli P, Westphal M (2009a) Terlipressin: a promising vasoactive agent in hemodynamic support of septic shock. Expert Opin Pharmacother 10(15):2569–2575\nMorelli A, Ertmer C, Rehberg S, Lange M, Orecchioni A, Cecchini V, Bachetoni A, D’Alessandro M, Van Aken H, Pietropaoli P et al (2009b) Continuous terlipressin versus vasopressin infusion in septic shock (TERLIVAP): a randomized, controlled pilot study. Crit Care 13(4):R130\nNantel P, Rene de Cotret P (2010) The evolution of angiotensin blockade in the management of cardiovascular disease. Can J Cardiol 26 Suppl E:7E-13E\nNoto A, Lentini S, Versaci A, Giardina M, Risitano DC, Messina R, David A (2009) A retrospective analysis of terlipressin in bolus for the management of refractory vasoplegic hypotension after cardiac surgery. Interact Cardiovasc Thorac Surg 9(4):588–592\nNygren A, Thoren A, Ricksten SE (2006) Vasopressors and intestinal mucosal perfusion after cardiac surgery: Norepinephrine vs. phenylephrine. Crit Care Med 34(3):722–729\nOh YJ, Lee JH, Nam SB, Shim JK, Song JH, Kwak YL (2006) Effects of chronic angiotensin II receptor antagonist and angiotensin-converting enzyme inhibitor treatments on neurohormonal levels and haemodynamics during cardiopulmonary bypass. Br J Anaesth 97(6):792–798\nOmar S, Zedan A, Nugent K (2015) Cardiac vasoplegia syndrome: pathophysiology, risk factors and treatment. Am J Med Sci 349(1):80–88\nPapadopoulos G, Sintou E, Siminelakis S, Koletsis E, Baikoussis NG, Apostolakis E (2010) Perioperative infusion of low- dose of vasopressin for prevention and management of vasodilatory vasoplegic syndrome in patients undergoing coronary artery bypass grafting-A double-blind randomized study. J Cardiothorac Surg 5:17\nPesaturo AB, Jennings HR, Voils SA (2006) Terlipressin: vasopressin analog and novel drug for septic shock. Ann Pharmacother 40(12):2170–2177\nSchulz KF, Altman DG, Moher D (2010) CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials. BMC Medicine 8(1)\nSummerhill EM, Baram M (2005) Principles of Pulmonary Artery Catheterization in the Critically Ill. Lung 183(3):209–219\nVijayaraghavan K, Deedwania P (2011) Renin-angiotensin-aldosterone blockade for cardiovascular disease prevention. Cardiol Clin 29(1):137–156\nXiao X, Zhang J, Wang Y, Zhou J, Zhu Y, Jiang D, Liu L, Li T (2016) Effects of terlipressin on patients with sepsis via improving tissue blood flow. J Surg Res 200(1):274–282\nYusuf S, Teo KK, Pogue J, Dyal L, Copland I, Schumacher H, Dagenais G, Sleight P, Anderson C (2008) Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med 358(15):1547–1559",{"VOID":1234},"10.1186\u002Fs42077-020-0054-6","http:\u002F\u002Flink.springer.com\u002F10.1186\u002Fs42077-020-0054-6",[1237,1252,1265],{"id":1238,"sortIndex":19,"researcher":18,"roles":1239,"affiliations":1240,"properties":1249,"displayName":1251,"givenName":18,"familyName":18},"4cb95712-075c-4a7d-8717-874faa7c4224",[92],[1241],{"id":1242,"sortIndex":19,"affiliation":1243,"properties":18},"9db22df0-fe15-4171-ac6a-ef880c646e4d",{"id":1242,"createTime":18,"updateTime":18,"relativeEntities":1244,"slug":18,"properties":1245,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":1248,"statistic":18},[],{"title":1246},{"VI":1247},"Department of Anesthesiology, Intensive Care and Pain Management, Faculty of Medicine, Ain-Shams University, Cairo, Egypt",[],{"title":1250},{"VI":1251},"Mohamed Saleh",{"id":1253,"sortIndex":58,"researcher":18,"roles":1254,"affiliations":1255,"properties":1262,"displayName":1264,"givenName":18,"familyName":18},"7d2d1d65-4527-4044-b4f9-25e38865958b",[92],[1256],{"id":1242,"sortIndex":19,"affiliation":1257,"properties":18},{"id":1242,"createTime":18,"updateTime":18,"relativeEntities":1258,"slug":18,"properties":1259,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":1261,"statistic":18},[],{"title":1260},{"VI":1247},[],{"title":1263},{"VI":1264},"Sherine Kamal Zaki Kodeira",{"id":1266,"sortIndex":122,"researcher":18,"roles":1267,"affiliations":1268,"properties":1275,"displayName":1277,"givenName":18,"familyName":18},"f24ad66a-1dde-457a-91b2-72d7465fc0e2",[92],[1269],{"id":1242,"sortIndex":19,"affiliation":1270,"properties":18},{"id":1242,"createTime":18,"updateTime":18,"relativeEntities":1271,"slug":18,"properties":1272,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":1274,"statistic":18},[],{"title":1273},{"VI":1247},[],{"title":1276},{"VI":1277},"Abdelkhalek Abdelmoneim Aboulseoud",{"url":1235,"publisher":1279,"properties":1308},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1280,"slug":10,"properties":1281,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":1284,"manageAffiliations":1289,"indexDatabases":1295,"url":53,"thumbnailPath":18,"statistic":1303,"gsStatistic":18,"type":61,"analyzePriority":18},[],{"issn":1282,"title":1283},{"VOID":13},{"EN":15},[1285],{"id":22,"createTime":18,"updateTime":18,"relativeEntities":1286,"label":1287,"description":1288,"parentId":18,"standard":18,"scholarHubFieldId":18},[],{"EN":25},{},[1290],{"id":29,"createTime":18,"updateTime":18,"relativeEntities":1291,"slug":18,"properties":1292,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":1294,"statistic":18},[],{"title":1293},{"EN":33},[],[1296],{"id":37,"indexDatabase":1297,"url":50,"indexYears":18,"academicFieldIds":1302,"indexDatabaseRanking":18},{"id":39,"createTime":18,"updateTime":18,"relativeEntities":1298,"label":1299,"description":1300,"key":46,"publicationTags":1301,"standard":18},[],{"EN":42,"VI":42},{"EN":44,"VI":45},[48,49],[52],{"impactFactor":19,"impactFactorByYear":1304,"i10Index":19,"i10IndexLast5Year":19,"totalPublication":56,"totalPublicationByYear":1305,"totalCitation":19,"totalCitationByYear":1306,"totalCitationPerPublication":19,"totalCitationPerPublicationByYear":1307,"hindexLast5Year":19,"hindex":19},{},{"2019":58,"2020":58,"2022":58},{},{},{"pages":1309,"volume":1311},{"VOID":1310},"1-9",{"VOID":1312},"12","2020-02-18",2020,[48],{"id":1317,"createTime":1318,"updateTime":1319,"relativeEntities":1320,"slug":1321,"properties":1322,"entityType":83,"verifyStatus":84,"verifyTime":1319,"verifyNote":86,"languages":18,"translateLanguages":18,"viewCount":19,"primaryUrl":1331,"fullTextUrl":18,"authors":1332,"publicationType":161,"publisherRelationship":1387,"citationCount":18,"citationInfo":18,"publishDate":1421,"publishYear":1314,"citationAnalyzeStatus":17,"lastCitationAnalyze":18,"indexDatabases":1422,"openAccess":18,"references":18,"isForceReanalyzing":204},"f9a8638d-5202-4f89-b440-34f658048d7d","2023-12-13T06:19:58.415+00:00","2025-02-25T07:40:10.966+00:00",[],"Prediction-of-fluid-responsiveness-in-mechanically-ventilated-patients-in-surgical-intensive-care-unit-by-pleth-variability-index-and-inferior-vena-cava-diameter",{"abstract":1323,"title":1325,"references":1327,"doi":1329},{"EN":1324},"Patients may have signs of hypovolemia, but fluid administration is not always beneficial. We are in need of bedside devices and techniques, which can predict fluid responsiveness effectively and safely. This study is aiming to compare the effectiveness and reliability of the pleth variability index (PVI) and IVC distensibility index (dIVC) as predictors of fluid responsiveness by simultaneous recordings in all sedated mechanically ventilated patients in the surgical intensive care unit (ICU). We used the passive leg raising test (PLR) as a harmless reversible technique for fluid challenge, and patients were considered responders if the cardiac index (CI) measured by transthoracic echocardiography (TTE) increased ≥ 15% after passive leg raising test (PLR). This observational cross-sectional study was performed randomly on 88 intubated ventilated sedated patients. Compared with CI measured by transthoracic echocardiography, the dIVC provided 79.17% sensitivity and 80% specificity at a threshold value of > 19.42% for fluid responsiveness prediction and was statistically significant (P \u003C .0001), with an area under the curve (AUC) of 0.886 (0.801–0.944), while PVI at a threshold value of > 14% provided 93.75% sensitivity and 87.5% specificity and was statistically significant (P \u003C .0001), with an AUC of 0.969 (0.889–0.988). PVI and dIVC are effective non-invasive bedside methods for the assessment of fluid responsiveness in ICU for intubated ventilated sedated patients with sinus rhythm, but PVI has the advantage of being continuous, operator-independent, and more reliable than dIVC.",{"EN":1326},"Prediction of fluid responsiveness in mechanically ventilated patients in surgical intensive care unit by pleth variability index and inferior vena cava diameter",{"VOID":1328},"Barbier C, Loubières Y, Schmit C, Hayon J, Ricôme JL, Jardin F, Vieillard-Baron A (2004) Respiratory changes in inferior vena cava diameter are helpful in predicting fluid responsiveness in ventilated septic patients. Intensive Care Medicine 30(9):1740–1746\nBendjelid K, Romand JA (2012) Fluid responsiveness in mechanically ventilated patients: a review of indices used in intensive care, In Applied Physiology in Intensive Care Medicine 2 (pp. 3-11). Springer, Berlin, Heidelberg\nBroch O, Bein B, Gruenewald M, Höcker J, Schöttler J, Meybohm P, Renner J (2011) Accuracy of the pleth variability index to predict fluid responsiveness depends on the perfusion index. Acta Anaesthesiologica Scandinavica 55(6):686–693\nCannesson M, De Backer D, Hofer CK (2011) Using arterial pressure waveform analysis for the assessment of fluid responsiveness. Expert Review of Medical Devices 8(5):635–646\nCharbonneau H, Riu B, Faron M, Mari A, Kurrek MM, Ruiz J et al (2014) Predicting preload responsiveness using simultaneous recordings of inferior and superior vena cavae diameters. Critical Care 18(5):473\nChatterjee K (2009) The Swan-Ganz catheters: past, present, and future: a viewpoint. Circulation 119(1):147–152\nChu H, Wang Y, Sun Y, Wang G (2016) Accuracy of pleth variability index to predict fluid responsiveness in mechanically ventilated patients: a systematic review and meta-analysis. Journal of Clinical Monitoring and Computing 30(3):265–274\nCumpstey AF, Grocott MP, Mythen MMG (2016) Fluid management and its role in enhanced recovery, In Perioperative Fluid Management (pp. 299-321). Springer, Cham\nDe Backer D, Fagnoul D (2014) Intensive care ultrasound: VI. Fluid responsiveness and shock assessment. Annals of the American Thoracic Society 11(1):129–136\nDesai N, Garry D (2018) Assessing dynamic fluid-responsiveness using transthoracic echocardiography in intensive care. BJA Education 18(7):218–226\nDesgranges FP, Desebbe O, Ghazouani A, Gilbert K, Keller G, Chiari P, Cannesson M (2011) Influence of the site of measurement on the ability of plethysmographic variability index to predict fluid responsiveness. British Journal of Anaesthesia 107(3):329–335\nEvans D, Ferraioli G, Snellings J, Levitov A (2014) Volume responsiveness in critically ill patients: use of sonography to guide management. Journal of Ultrasound in Medicine 33(1):3–7\nForget P, Lois F, De Kock M (2010) Goal-directed fluid management based on the pulse oximeter–derived pleth variability index reduces lactate levels and improves fluid management. Anesthesia & Analgesia 111(4):910–914\nGuérin L, Monnet X, Teboul JL (2013) Monitoring volume and fluid responsiveness: from static to dynamic indicators. Best Practice & Research Clinical Anaesthesiology 27(2):177–185\nHaas S, Trepte C, Hinteregger M, Fahje R, Sill B, Herich L, Reuter DA (2012) Prediction of volume responsiveness using pleth variability index in patients undergoing cardiac surgery after cardiopulmonary bypass. Journal of Anesthesia 26(5):696–701\nHuang H, Shen Q, Liu Y, Xu H, Fang Y (2018) Value of variation index of inferior vena cava diameter in predicting fluid responsiveness in patients with circulatory shock receiving mechanical ventilation: a systematic review and meta-analysis. Critical Care 22(1):1–7\nJalil BA, Cavallazzi R (2018) Predicting fluid responsiveness: a review of literature and a guide for the clinician. The American Journal of Emergency Medicine 36(11):2093–2102\nKeller G, Cassar E, Desebbe O, Lehot JJ, Cannesson M (2008) Ability of pleth variability index to detect hemodynamic changes induced by passive leg raising in spontaneously breathing volunteers. Critical Care 12(2):R37\nKnaus WA, Draper EA, Wagner DP, Zimmerman JE (1985) APACHE II: a severity of disease classification system. Critical Care Medicine 13(10):818–829\nLakhal K, Ehrmann S, Benzekri-Lefèvre D, Runge I, Legras A, Dequin PF et al (2011) Respiratory pulse pressure variation fails to predict fluid responsiveness in acute respiratory distress syndrome. Critical Care 15(2):R85\nLiu T, Xu C, Wang M, Niu Z, Qi D (2019) Reliability of pleth variability index in predicting preload responsiveness of mechanically ventilated patients under various conditions: a systematic review and meta-analysis. BMC Anesthesiology 19(1):1–7\nLong E, Oakley E, Duke T, Babl FE, Paediatric Research in Emergency Departments International Collaborative (PREDICT) (2017) Does respiratory variation in inferior vena cava diameter predict fluid responsiveness: a systematic review and meta-analysis. Shock (Augusta, Ga.) 47(5):550–559\nMarik PE, Cavallazzi R (2013) Does the central venous pressure predict fluid responsiveness? An updated meta-analysis and a plea for some common sense. Critical Care Medicine 41(7):1774–1781\nMarik PE, Lemson J (2014) Fluid responsiveness: an evolution of our understanding. British Journal of Anaesthesia 112(4):617–620\nMatta JL, Kraemer CE, Tuinman PR, van Westerloo DJ (2019) POCUS series: the use of velocity time integral in assessing cardiac output and fluid responsiveness. Netherlands Journal of Critical Care 27(5):196–198\nMichard F, Boussat S, Chemla D, Anguel N, Mercat A, Lecarpentier Y et al (2000) Relation between respiratory changes in arterial pulse pressure and fluid responsiveness in septic patients with acute circulatory failure. American Journal of Respiratory and Critical Care Medicine 162(1):134–138\nMiller A, Mandeville J (2016) Predicting and measuring fluid responsiveness with echocardiography. Echo Research and Practice 3(2):G1–G12\nMonnet X, Guérin L, Jozwiak M, Bataille A, Julien F, Richard C, Teboul JL (2013) Pleth variability index is a weak predictor of fluid responsiveness in patients receiving norepinephrine. British Journal of Anaesthesia 110(2):207–213\nMonnet X, Marik PE, Teboul JL (2016) Prediction of fluid responsiveness: an update. Annals of Intensive Care 6(1):111\nMuller L, Toumi M, Bousquet PJ, Riu-Poulenc B, Louart G, Candela D et al (2011) An increase in aortic blood flow after an infusion of 100 ml colloid over 1 minute can predict fluid responsiveness: the mini-fluid challenge study. Anesthesiology: The Journal of the American Society of Anesthesiologists 115(3):541–547\nOrso D, Guglielmo N, Federici N, Cugini F, Ban A, Mearelli F, Copetti R (2016) Accuracy of the caval index and the expiratory diameter of the inferior vena cava for the diagnosis of dehydration in elderly. Journal of Ultrasound 19(3):203–209\nPierrakos C, Velissaris D, Scolletta S, Heenen S, De Backer D, Vincent JL (2012) Can changes in arterial pressure be used to detect changes in cardiac index during fluid challenge in patients with septic shock? Intensive Care Medicine 38(3):422–428\nPişkin Ö, Öz İİ (2017) Accuracy of pleth variability index compared with inferior vena cava diameter to predict fluid responsiveness in mechanically ventilated patients. Medicine 96(47):e8889\nRamsay MAE, Savege TM, Simpson BRJ, Goodwin R (1974) Controlled sedation with alphaxalone-alphadolone. Br med J 2(5920):656–659\nSakr Y, Rubatto Birri PN, Kotfis K, Nanchal R, Shah B, Kluge S et al (2017) Higher fluid balance increases the risk of death from sepsis: results from a large international audit. Critical Care Medicine 45(3):386–394\nSandroni C, Cavallaro F, Marano C, Falcone C, De Santis P, Antonelli M (2012) Accuracy of plethysmographic indices as predictors of fluid responsiveness in mechanically ventilated adults: a systematic review and meta-analysis. Intensive Care Medicine 38(9):1429–1437\nSanta-Teresa P, Muñoz J, Montero I, Zurita M, Tomey M, Álvarez-Sala L, García P (2012) Incidence and prognosis of intra-abdominal hypertension in critically ill medical patients: a prospective epidemiological study. Annals of Intensive Care 2(S1):S3\nScheer BV, Perel A, Pfeiffer UJ (2002) Clinical review: complications and risk factors of peripheral arterial catheters used for haemodynamic monitoring in anaesthesia and intensive care medicine. Critical Care 6(3):199\nTheerawit P, Morasert T, Sutherasan Y (2016) Inferior vena cava diameter variation compared with pulse pressure variation as predictors of fluid responsiveness in patients with sepsis. Journal of Critical Care 36:246–251\nWise R, Faurie M, Malbrain ML, Hodgson E (2017) Strategies for intravenous fluid resuscitation in trauma patients. World Journal of Surgery 41(5):1170–1183\nXiang SI, Cao D, Wu J, Chen J, Liu Z, Chen M et al (2016) Diagnostic accuracy of transthoracic echocardiography to predict fluid responsiveness by passive leg raising in the critically ill: a meta-analysis. Open Journal of Emergency Medicine 4(04):83\nYamaura K, Irita K, Kandabashi T, Tohyama K, Takahashi S (2007) Evaluation of finger and forehead pulse oximeters during mild hypothermic cardiopulmonary bypass. Journal of Clinical Monitoring and Computing 21(4):249–252",{"VOID":1330},"10.1186\u002Fs42077-020-00097-4","https:\u002F\u002Flink.springer.com\u002F10.1186\u002Fs42077-020-00097-4",[1333,1346,1359,1374],{"id":1334,"sortIndex":19,"researcher":18,"roles":1335,"affiliations":1336,"properties":1343,"displayName":1345,"givenName":18,"familyName":18},"912b2382-10b6-4465-88f0-e16c0c773d2b",[92],[1337],{"id":1242,"sortIndex":19,"affiliation":1338,"properties":18},{"id":1242,"createTime":18,"updateTime":18,"relativeEntities":1339,"slug":18,"properties":1340,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":1342,"statistic":18},[],{"title":1341},{"VI":1247},[],{"title":1344},{"VI":1345},"Diaaeldin Badr Metwally Kotb 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Elseidy",{"id":1360,"sortIndex":122,"researcher":18,"roles":1361,"affiliations":1362,"properties":1371,"displayName":1373,"givenName":18,"familyName":18},"8c58313e-ef2f-4dde-b483-9728844946c7",[92],[1363],{"id":1364,"sortIndex":19,"affiliation":1365,"properties":18},"e5483824-6208-4be9-934b-6d46ac094de0",{"id":1364,"createTime":18,"updateTime":18,"relativeEntities":1366,"slug":18,"properties":1367,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":1370,"statistic":18},[],{"title":1368},{"VI":1369},"Department of Anesthesiology, Intensive Care, and Pain Management, Faculty of Medicine, Ain Shams University, Cairo, Egypt",[],{"title":1372},{"VI":1373},"Yasir Ahmed Elbasiony Mohamed Kenawey",{"id":1375,"sortIndex":56,"researcher":18,"roles":1376,"affiliations":1377,"properties":1384,"displayName":1386,"givenName":18,"familyName":18},"253ed070-7a00-4528-a7d8-4c3612a10612",[92],[1378],{"id":1242,"sortIndex":19,"affiliation":1379,"properties":18},{"id":1242,"createTime":18,"updateTime":18,"relativeEntities":1380,"slug":18,"properties":1381,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":1383,"statistic":18},[],{"title":1382},{"VI":1247},[],{"title":1385},{"VI":1386},"Ibrahim Mohammed Alsayed Ahmed Elsherif",{"url":1331,"publisher":1388,"properties":1417},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1389,"slug":10,"properties":1390,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":1393,"manageAffiliations":1398,"indexDatabases":1404,"url":53,"thumbnailPath":18,"statistic":1412,"gsStatistic":18,"type":61,"analyzePriority":18},[],{"issn":1391,"title":1392},{"VOID":13},{"EN":15},[1394],{"id":22,"createTime":18,"updateTime":18,"relativeEntities":1395,"label":1396,"description":1397,"parentId":18,"standard":18,"scholarHubFieldId":18},[],{"EN":25},{},[1399],{"id":29,"createTime":18,"updateTime":18,"relativeEntities":1400,"slug":18,"properties":1401,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":1403,"statistic":18},[],{"title":1402},{"EN":33},[],[1405],{"id":37,"indexDatabase":1406,"url":50,"indexYears":18,"academicFieldIds":1411,"indexDatabaseRanking":18},{"id":39,"createTime":18,"updateTime":18,"relativeEntities":1407,"label":1408,"description":1409,"key":46,"publicationTags":1410,"standard":18},[],{"EN":42,"VI":42},{"EN":44,"VI":45},[48,49],[52],{"impactFactor":19,"impactFactorByYear":1413,"i10Index":19,"i10IndexLast5Year":19,"totalPublication":56,"totalPublicationByYear":1414,"totalCitation":19,"totalCitationByYear":1415,"totalCitationPerPublication":19,"totalCitationPerPublicationByYear":1416,"hindexLast5Year":19,"hindex":19},{},{"2019":58,"2020":58,"2022":58},{},{},{"pages":1418,"volume":1420},{"VOID":1419},"1-7",{"VOID":1312},"2020-10-07",[48],{"id":1424,"createTime":1425,"updateTime":1426,"relativeEntities":1427,"slug":1428,"properties":1429,"entityType":83,"verifyStatus":84,"verifyTime":1426,"verifyNote":86,"languages":18,"translateLanguages":18,"viewCount":19,"primaryUrl":1438,"fullTextUrl":18,"authors":1439,"publicationType":161,"publisherRelationship":1494,"citationCount":18,"citationInfo":18,"publishDate":1528,"publishYear":346,"citationAnalyzeStatus":17,"lastCitationAnalyze":18,"indexDatabases":1529,"openAccess":18,"references":18,"isForceReanalyzing":204},"bb4067eb-2df8-40f0-b43b-cb39c52cb782","2024-02-14T14:36:11.457+00:00","2025-02-25T04:27:13.179+00:00",[],"Restrictive-versus-liberal-perioperative-fluid-strategies-to-prevent-post-dural-puncture-headache-after-cesarean-delivery",{"abstract":1430,"title":1432,"references":1434,"doi":1436},{"EN":1431},"Post-dural puncture headache is a common complication after cesarean delivery. The role of fluid therapy in prevention of post-dural puncture headache is not clear. The aim of this work is to compare restrictive versus liberal perioperative fluid protocols in prevention of post-dural puncture headache. A randomized controlled trial was conducted including 100 full-term pregnant women undergoing cesarean delivery under spinal block. After receiving spinal block, all patients received 1.5 mcg\u002Fkg phenylephrine and crystalloid co-load at a rate of 10 mL\u002Fh. Patients were assigned into either restrictive group (did not receive fluid preload + received postoperative crystalloid therapy at a rate of 2 mL\u002Fkg\u002Fh till resuming oral fluids) or liberal group (received crystalloid preload 5 mL\u002Fkg before spinal block + received postoperative crystalloids at a rate of 6 mL\u002Fkg\u002Fh till resuming oral fluids. Both groups were compared according to the incidence of post-dural puncture headache, pain scores, systolic blood pressure, heart rate, incidence of post-spinal hypotension, nausea, and vomiting. The incidence of post-dural puncture headache was lower in the restrictive group compared to the liberal group {10(20%) vs 22(44%), P = 0.018}. All other secondary outcomes were comparable between both groups. Restrictive fluid therapy was associated with lower incidence of PDPH after cesarean delivery without impacting patient hemodynamic profile.",{"EN":1433},"Restrictive versus liberal perioperative fluid strategies to prevent post-dural puncture headache after cesarean delivery",{"VOID":1435},"Afshinmajd S, Davati A, Ahmadvand A, Modara F, Moghaddamnia M, Jaberian M (2014) Evaluation of the effects of resting in appearance of post lumbar puncture headache. Acta Med Iran 52:43–45\nAhmed SV, Jayawarna C, Jude E (2006) Post lumbar puncture headache: diagnosis and management. Postgrad Med J 82:713–716\nApfel CC, Saxena A, Cakmakkaya OS, Gaiser R, George E, Radke O (2010) Prevention of postdural puncture headache after accidental dural puncture: a quantitative systematic review. BJA Br J Anaesth 105:255–263\nArevalo-Rodriguez I, Ciapponi A, Munoz L, Roqué i Figuls M, Bonfill CX (2013) Posture and fluids for preventing post-dural puncture headache. In: Arevalo-Rodriguez I (ed) Cochrane Database Syst. Rev. John Wiley & Sons, Ltd, Chichester, UK, p CD009199\nArevalo-Rodriguez I, Ciapponi A, Roqué i Figuls M, Muñoz L, Bonfill CX (2016) Posture and fluids for preventing post-dural puncture headache. Cochrane Database Syst Rev 3:CD009199\nBezov D, Lipton RB, Ashina S (2010) Post-dural puncture headache: part i diagnosis, epidemiology, etiology, and pathophysiology. Headache J Head Face Pain 50:1144–1152\nBradbury CL, Singh SI, Badder SR, Wakely LJ, Jones PM (2013) Prevention of post-dural puncture headache in parturients: a systematic review and meta-analysis. Acta Anaesthesiol Scand 57:417–430\nBuddeberg BS, Bandschapp O, Girard T (2019) Post dural puncture headache: a review of the literature. Minerva Anestesiol. https:\u002F\u002Fdoi.org\u002F10.23736\u002Fs0375-9393.18.13331-1\nClark JW, Solomon GD, Senanayake PD, Gallagher C (1996) Substance P concentration and history of headache in relation to postlumbar puncture headache: towards prevention. J Neurol Neurosurg Psychiatry 60:681–683\nDella Rocca G, Tripi G, Pompei L (2014) Free fluid therapy is best. Liberal or restricted fluid administration: are we ready for a proposal of a restricted approch? BMC Anesthesiol 14:62\nDieterich M, Brandt T (1988) Incidence of post-lumbar puncture headache is independent of daily fluid intake. Eur Arch Psychiatry Neurol Sci 237:194–196\nIoscovich A, Giladi Y, Fuica RL, Weiniger CF, Orbach-Zinger S, Gozal Y, Shatalin D (2018) Anesthetic approach to postdural puncture headache in the peripartum period: An Israeli national survey. Acta Anaesthesiol Scand 62:1460–1465\nJensen TT, Eggert W, Hansen KF, Fink M (1987) Side-effects of lumbar metrizamide myelography in ambulant patients and patients confined to bed. Ugeskr Laeger 149:2016–2017\nKim SR, Chae HS, Yoon MJ, Han JH, Cho KJ, Chung SJ (2012) No effect of recumbency duration on the occurrence of post-lumbar puncture headache with a 22G cutting needle. BMC Neurol 12:1\nMartin JA, Hamilton BE, Osterman MJ, Curtin SC, Matthews TJ (2015) Births: final data for 2013. Natl Vital Stat Rep 64:1–65\nMiró J, Castarlenas E, de la Vega R, Solé E, Tomé-Pires C, Jensen MP et al (2016) Validity of three rating scales for measuring pain intensity in youths with physical disabilities. Eur J Pain 20:130–137\nOsterman MJK, Martin JA (2011) Epidural and spinal anesthesia use during labor: 27-state reporting area, 2008. Natl Vital Stat Rep 59:1–13 16\nSimões CM, Carmona MJC, Hajjar LA, Vincent J-L, Landoni G, Belletti A et al (2018) Predictors of major complications after elective abdominal surgery in cancer patients. BMC Anesthesiol 18:49\nSprigge JS, Harper SJ (2007) Accidental dural puncture and post dural puncture headache in obstetric anaesthesia: presentation and management: a 23-year survey in a district general hospital. Anaesthesia 63:36–43",{"VOID":1437},"10.1186\u002Fs42077-021-00134-w","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1186\u002Fs42077-021-00134-w",[1440,1455,1468,1481],{"id":1441,"sortIndex":19,"researcher":18,"roles":1442,"affiliations":1443,"properties":1452,"displayName":1454,"givenName":18,"familyName":18},"cd14b8a7-d2ea-4176-9d0f-77c7a079fba4",[92],[1444],{"id":1445,"sortIndex":19,"affiliation":1446,"properties":18},"f690b170-622b-47f4-a399-eba933adaaad",{"id":1445,"createTime":18,"updateTime":18,"relativeEntities":1447,"slug":18,"properties":1448,"entityType":18,"verifyStatus":18,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":18,"url":18,"parentIds":1451,"statistic":18},[],{"title":1449},{"VI":1450},"Department of Anesthesia and Critical Care Medicine, Faculty of Medicine, Cairo, Egypt",[],{"title":1453},{"VI":1454},"M. 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