T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection

Nature Medicine - Tập 13 Số 12 - Trang 1440-1449 - 2007
Matthias T. Stephan1,2, Vladimir Ponomarev3, Renier J. Brentjens4, Alex H. Chang1, Konstantin Dobrenkov3, Glenn Heller5, Michel Sadelain4,2
1Center for Cell Engineering, Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, USA
2Immunology Graduate Program, Weill Graduate School of Medical Sciences, Cornell University, New York, USA
3Department of Radiology, MSKCC, New York, USA
4Department of Medicine, MSKCC, New York, USA
5Department of Epidemiology and Biostatistics, MSKCC, New York, USA

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