LEP rs7799039, LEPR rs1137101, and ADIPOQ rs2241766 and 1501299 Polymorphisms Are Associated With Obesity and Chemotherapy Response in Mexican Women With Breast Cancer

De Santis, 2011, Breast cancer statistics, 2011, CA Cancer J Clin, 61, 408, 10.3322/caac.20134 Ferlay J, Soerjomataram I, Ervik M, et al. Cancer incidence and mortality worldwide: IARC CancerBase. GLOBOCAN 2012 v1. 0. 2013. Available at: http://globocan.iarc.fr. Yardley, 2010, A phase II trial of neoadjuvant gemcitabine, epirubicin, and docetaxel as primary treatment of patients with locally advanced or inflammatory breast cancer, Clin Breast Cancer, 10, 217, 10.3816/CBC.2010.n.029 Eisenhauer, 2009, New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1), Eur J Cancer, 45, 228, 10.1016/j.ejca.2008.10.026 Park, 2014, Obesity and cancer mechanisms underlying tumour progression and recurrence, Nat Rev Endocrinol, 10, 455, 10.1038/nrendo.2014.94 James, 2015, Obesity in breast cancer–what is the risk factor?, Eur J Cancer, 51, 705, 10.1016/j.ejca.2015.01.057 Fantuzzi, 2005, Adipose tissue, adipokines, and inflammation, J Allergy Clin Immunol, 115, 911, 10.1016/j.jaci.2005.02.023 Han, 2008, Associations among lipids, leptin, and leptin receptor gene Gln223Arg polymorphisms and breast cancer in China, Biol Trace Elem Res, 126, 38, 10.1007/s12011-008-8182-z He, 2013, Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling, Cell, 155, 384, 10.1016/j.cell.2013.09.031 Teras, 2009, No association between polymorphisms in LEP, LEPR, ADIPOQ, ADIPOR1, or ADIPOR2 and postmenopausal breast cancer risk, Cancer Epidemiol Biomarkers Prev, 18, 2553, 10.1158/1055-9965.EPI-09-0542 Liu, 2007, The roles of serum leptin concentration and polymorphism in leptin receptor gene at codon 109 in breast cancer, Oncology, 72, 75, 10.1159/000111097 Cleveland, 2010, Common genetic variations in the LEP and LEPR genes, obesity and breast cancer incidence and survival, Breast Cancer Res Treat, 120, 745, 10.1007/s10549-009-0503-1 Mohammadzadeh, 2014, Effect of leptin receptor Q223R polymorphism on breast cancer risk, Iran J Basic Med Sci, 17, 588 Grossmann, 2012, The balance between leptin and adiponectin in the control of carcinogenesis–focus on mammary tumorigenesis, Biochimie, 94, 2164, 10.1016/j.biochi.2012.06.013 Khan, 2013, Role of adipokines and cytokines in obesity-associated breast cancer: therapeutic targets, Cytokine Growth Factor Rev, 24, 503, 10.1016/j.cytogfr.2013.10.001 Yang, 2013, ADIPOQ gene polymorphisms and cancer risk: a meta-analysis, Cytokine, 61, 565, 10.1016/j.cyto.2012.10.030 Kaklamani, 2013, Adiponectin pathway polymorphisms and risk of breast cancer in African Americans and Hispanics in the Women's Health Initiative, Breast Cancer Res Treat, 139, 461, 10.1007/s10549-013-2546-6 Miller, 1988, A simple salting out procedure for extracting DNA from human nucleated cells, Nucleic Acids Res, 16, 1215, 10.1093/nar/16.3.1215 Borgquist, 2009, Anthropometric factors in relation to different tumor biological subgroups of postmenopausal breast cancer, Int J Cancer, 124, 402, 10.1002/ijc.23850 Ray, 2012, Obesity and breast cancer: a clinical biochemistry perspective, Clin Biochem, 45, 189, 10.1016/j.clinbiochem.2011.11.016 Lorincz, 2006, Molecular links between obesity and breast cancer, Endocr Relat Cancer, 13, 279, 10.1677/erc.1.00729 Ghalandari, 2015, The association of polymorphisms in leptin/leptin receptor genes and ghrelin/ghrelin receptor genes with overweight/obesity and the related metabolic disturbances: a review, Int J Endocrinol Metab, 13, e19073, 10.5812/ijem.19073v2 Parekh, 2012, Obesity in cancer survival, Annu Rev Nutr, 32, 311, 10.1146/annurev-nutr-071811-150713 Yom, 2013, Leptin as a potential target for estrogen receptor-positive breast cancer, J Breast Cancer, 16, 138, 10.4048/jbc.2013.16.2.138 Newman, 2014, Leptin–cytokine crosstalk in breast cancer, Mol Cell Endocrinol, 382, 570, 10.1016/j.mce.2013.03.025 Catalano, 2004, Leptin induces, via ERK1/ERK2 signal, functional activation of estrogen receptor α in MCF-7 cells, J Biol Chem, 279, 19908, 10.1074/jbc.M313191200 Chavarria-Avila, 2015, The impact of LEP G-2548A and LEPR Gln223Arg polymorphisms on adiposity, leptin, and leptin-receptor serum levels in a Mexican Mestizo population, Biomed Res Int, 2015, 539408, 10.1155/2015/539408 Symmans, 2015, Measurement of residual breast cancer burden to predict survival after neoadjuvant chemotherapy, J Clin Oncol, 25, 4414, 10.1200/JCO.2007.10.6823