Engineering CAR-T Cells for Next-Generation Cancer Therapy
Tài liệu tham khảo
Alizadeh, 2019, IL15 enhances CAR-T cell antitumor activity by reducing mTORC1 activity and preserving their stem cell memory phenotype, Cancer Immunol. Res., 7, 759, 10.1158/2326-6066.CIR-18-0466
Batra, 2020, Glypican-3-specific CAR T cells co-expressing IL15 and IL21 have superior expansion and antitumor activity against hepatocellular carcinoma, Cancer Immunol. Res., 10.1158/2326-6066.CIR-19-0293
Beatty, 2014, Mesothelin-specific chimeric antigen receptor mRNA-engineered T cells induce anti-tumor activity in solid malignancies, Cancer Immunol. Res., 2, 112, 10.1158/2326-6066.CIR-13-0170
Bouchkouj, 2019, FDA approval summary: axicabtagene ciloleucel for relapsed or refractory large B-cell lymphoma, Clin. Cancer Res., 25, 1702, 10.1158/1078-0432.CCR-18-2743
Buchbinder, 2016, CTLA-4 and PD-1 pathways: similarities, differences, and implications of their inhibition, Am. J. Clin. Oncol., 39, 98, 10.1097/COC.0000000000000239
Chinnasamy, 2012, Local delivery of interleukin-12 using T cells targeting VEGF receptor-2 eradicates multiple vascularized tumors in mice, Clin. Cancer Res., 18, 1672, 10.1158/1078-0432.CCR-11-3050
Craddock, 2010, Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b, J. Immunother., 33, 780, 10.1097/CJI.0b013e3181ee6675
Di Stasi, 2011, Inducible apoptosis as a safety switch for adoptive cell therapy, N. Engl. J. Med., 365, 1673, 10.1056/NEJMoa1106152
Drake, 2006, Mechanisms of immune evasion by tumors, Adv. Immunol., 90, 51, 10.1016/S0065-2776(06)90002-9
Eliopoulos, 2000, CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the tumor necrosis factor superfamily, Mol. Cell Biol., 20, 5503, 10.1128/MCB.20.15.5503-5515.2000
Fitzgerald, 2017, Cytokine release syndrome after chimeric antigen receptor T cell therapy for acute lymphoblastic leukemia, Crit. Care Med., 45, e124, 10.1097/CCM.0000000000002053
Grupp, 2013, Chimeric antigen receptor-modified T cells for acute lymphoid leukemia, N. Engl. J. Med., 368, 1509, 10.1056/NEJMoa1215134
Jung, 2018, CRISPR/Cas9-mediated knockout of DGK improves antitumor activities of human T cells, Cancer Res., 78, 4692, 10.1158/0008-5472.CAN-18-0030
Koneru, 2015, IL-12 secreting tumor-targeted chimeric antigen receptor T cells eradicate ovarian tumors in vivo, Oncoimmunology, 4, e994446, 10.4161/2162402X.2014.994446
Krenciute, 2017, Transgenic expression of IL15 improves antiglioma activity of IL13Ralpha2-CAR T cells but results in antigen loss variants, Cancer Immunol. Res., 5, 571, 10.1158/2326-6066.CIR-16-0376
Kuwana, 1987, Expression of chimeric receptor composed of immunoglobulin-derived V regions and T-cell receptor-derived C regions, Biochem. Biophys. Res. Commun., 149, 960, 10.1016/0006-291X(87)90502-X
Lee, 2019, Use of a single CAR T cell and several bispecific adapters facilitates eradication of multiple antigenically different solid tumors, Cancer Res., 79, 387, 10.1158/0008-5472.CAN-18-1834
Li, 2017, Enhanced cancer immunotherapy by chimeric antigen receptor-modified T cells engineered to secrete checkpoint inhibitors, Clin. Cancer Res., 23, 6982, 10.1158/1078-0432.CCR-17-0867
Liu, 2020, Use of CAR-transduced natural killer cells in CD19-positive lymphoid tumors, N. Engl. J. Med., 382, 545, 10.1056/NEJMoa1910607
Liu, 2016, A chimeric switch-receptor targeting PD1 augments the efficacy of second-generation CAR T cells in advanced solid tumors, Cancer Res., 76, 1578, 10.1158/0008-5472.CAN-15-2524
Mamonkin, 2018, Reversible transgene expression reduces fratricide and permits 4-1BB costimulation of CAR T cells directed to T-cell malignancies, Cancer Immunol. Res., 6, 47, 10.1158/2326-6066.CIR-17-0126
Maude, 2014, Chimeric antigen receptor T cells for sustained remissions in leukemia, N. Engl. J. Med., 371, 1507, 10.1056/NEJMoa1407222
Maus, 2013, T cells expressing chimeric antigen receptors can cause anaphylaxis in humans, Cancer Immunol. Res., 1, 26, 10.1158/2326-6066.CIR-13-0006
Menger, 2016, TALEN-mediated inactivation of PD-1 in tumor-reactive lymphocytes promotes intratumoral T-cell persistence and rejection of established tumors, Cancer Res., 76, 2087, 10.1158/0008-5472.CAN-15-3352
Moon, 2011, Expression of a functional CCR2 receptor enhances tumor localization and tumor eradication by retargeted human T cells expressing a mesothelin-specific chimeric antibody receptor, Clin. Cancer Res., 17, 4719, 10.1158/1078-0432.CCR-11-0351
Neelapu, 2017, Axicabtagene ciloleucel CAR T-cell therapy in refractory large B-cell lymphoma, N. Engl. J. Med., 377, 2531, 10.1056/NEJMoa1707447
Newick, 2016, Augmentation of CAR T-cell trafficking and antitumor efficacy by blocking protein kinase A localization, Cancer Immunol. Res., 4, 541, 10.1158/2326-6066.CIR-15-0263
O'Leary, 2019, FDA approval summary: tisagenlecleucel for treatment of patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia, Clin. Cancer Res., 25, 1142, 10.1158/1078-0432.CCR-18-2035
Parihar, 2019, NK cells expressing a chimeric activating receptor eliminate MDSCs and rescue impaired CAR-T cell activity against solid tumors, Cancer Immunol. Res., 7, 363, 10.1158/2326-6066.CIR-18-0572
Ren, 2017, Multiplex genome editing to generate universal CAR T cells resistant to PD1 Inhibition, Clin. Cancer Res., 23, 2255, 10.1158/1078-0432.CCR-16-1300
Ricciotti, 2011, Prostaglandins and inflammation, Arterioscler Thromb. Vasc. Biol., 31, 986, 10.1161/ATVBAHA.110.207449
Riese, 2013, Enhanced effector responses in activated CD8+ T cells deficient in diacylglycerol kinases, Cancer Res., 73, 3566, 10.1158/0008-5472.CAN-12-3874
Sakemura, 2016, A Tet-On inducible system for controlling CD19-chimeric antigen receptor expression upon drug administration, Cancer Immunol. Res., 4, 658, 10.1158/2326-6066.CIR-16-0043
Schmitt, 2002, Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro, Immunity, 17, 749, 10.1016/S1074-7613(02)00474-0
Schuster, 2017, Chimeric antigen receptor T cells in refractory B-cell lymphomas, N. Engl. J. Med., 377, 2545, 10.1056/NEJMoa1708566
Shah, 2020, CD4/CD8 T-cell selection affects chimeric antigen receptor (CAR) T-cell potency and toxicity: updated results from a phase I anti-CD22 CAR T-cell trial, J. Clin. Oncol., 38, 1938, 10.1200/JCO.19.03279
Shum, 2017, Constitutive signaling from an engineered IL7 receptor promotes durable tumor elimination by tumor-redirected T cells, Cancer Discov., 7, 1238, 10.1158/2159-8290.CD-17-0538
Tchou, 2017, Safety and efficacy of intratumoral injections of chimeric antigen receptor (CAR) T cells in metastatic breast cancer, Cancer Immunol. Res., 5, 1152, 10.1158/2326-6066.CIR-17-0189
Urbanska, 2012, A universal strategy for adoptive immunotherapy of cancer through use of a novel T-cell antigen receptor, Cancer Res., 72, 1844, 10.1158/0008-5472.CAN-11-3890
Wang, 2014, Targeting fibroblast activation protein in tumor stroma with chimeric antigen receptor T cells can inhibit tumor growth and augment host immunity without severe toxicity, Cancer Immunol. Res., 2, 154, 10.1158/2326-6066.CIR-13-0027
Wei, 2018, Fundamental mechanisms of immune checkpoint blockade therapy, Cancer Discov., 8, 1069, 10.1158/2159-8290.CD-18-0367
Wilkie, 2010, Selective expansion of chimeric antigen receptor-targeted T-cells with potent effector function using interleukin-4, J. Biol. Chem., 285, 25538, 10.1074/jbc.M110.127951
Woo, 2012, Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape, Cancer Res., 72, 917, 10.1158/0008-5472.CAN-11-1620
Xu, 2019, NKT cells coexpressing a GD2-specific chimeric antigen receptor and IL15 show enhanced in vivo persistence and antitumor activity against neuroblastoma, Clin. Cancer Res., 25, 7126, 10.1158/1078-0432.CCR-19-0421
Zah, 2016, T cells expressing CD19/CD20 bispecific chimeric antigen receptors prevent antigen escape by malignant B cells, Cancer Immunol. Res., 4, 498, 10.1158/2326-6066.CIR-15-0231