Discovery of the imidazole-derived GPR40 agonist AM-3189

Bioorganic & Medicinal Chemistry Letters - Tập 26 - Trang 15-20 - 2016
Zhihua Ma1, Daniel C.-H. Lin2, Rajiv Sharma1, Jinqian Liu1, Liusheng Zhu1, An-Rong Li1, Todd Kohn1, Yingcai Wang1, Jiwen (Jim) Liu1, Michael D. Bartberger1, Julio C. Medina1, Run Zhuang2, Frank Li2, Jane Zhang2, Jian Luo2, Simon Wong3, George R. Tonn3, Jonathan B. Houze1
1Department of Therapeutic Discovery, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, CA 94080, USA
2Department of Metabolic Disorders, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, CA 94080, USA
3Department of Pharmacokinetics & Drug Metabolism, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, CA 94080, USA

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Bioorganic & Medicinal Chemistry Letters

Tập 26

15-20

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