Development of 3-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine derivatives as novel Mycobacterium tuberculosis pantothenate synthetase inhibitors

European Journal of Medicinal Chemistry - Tập 69 - Trang 356-364 - 2013
Ganesh Samala1, Parthiban Brindha Devi1, Radhika Nallangi1, Perumal Yogeeswari1, Dharmarajan Sriram1
1Antitubercular Drug Discovery Laboratory, Department of Pharmacy, Birla Institute of Technology and Science – Pilani, Hyderabad Campus, Jawahar Nagar, Hyderabad 500 078, India

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Padmapriyadarsini, 2011, Indian J. Med. Res., 134, 850, 10.4103/0971-5916.92630

Zheng, 2001, Biochemistry, 40, 12904, 10.1021/bi011522+

Sambandamurthy, 2002, Nat. Med., 8, 1171, 10.1038/nm765

Sambandamurthy, 2005, Infect. Immun., 73, 1196, 10.1128/IAI.73.2.1196-1203.2005

Wang, 2003, Protein Sci., 12, 1097, 10.1110/ps.0241803

Velaparthi, 2008, J. Med. Chem., 51, 1999, 10.1021/jm701372r

Yang, 2011, Bioorg. Med. Chem. Lett., 21, 3943, 10.1016/j.bmcl.2011.05.021

White, 2007, J. Biomol. Screen., 12, 100, 10.1177/1087057106296484

Hung, 2009, Angew. Chem., 48, 8452, 10.1002/anie.200903821

Ye, 2010, Bioorg. Med. Chem. Lett., 20, 2195, 10.1016/j.bmcl.2010.02.039

National Committee for Clinical Laboratory Standards, 1995

Gundersen, 2002, J. Med. Chem., 45, 1383, 10.1021/jm0110284