Claudin-18 Loss Alters Transcellular Chloride Flux but not Tight Junction Ion Selectivity in Gastric Epithelial Cells

Tyler J. Caron1,2,3, Kathleen E. Scott1,2,3, Nishita Sinha1, Sureshkumar Muthupalani2, Mahnoor Baqai1,4, Lay-Hong Ang1,4, Yue Li1,4, Jerrold R. Turner4,5, James G. Fox2,3, Susan J. Hagen1,4
1Department of Surgery/Division of General Surgery, Beth Israel Deaconess Medical Center, Boston, Massachusetts
2Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts
3Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts
4Harvard Medical School, Boston, Massachusetts
5Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts

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