Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema

Cell - Tập 181 - Trang 784-799.e19 - 2020
Philip Kitchen1, Mootaz M. Salman2,3,4, Andrea M. Halsey5, Charlotte Clarke-Bland1, Justin A. MacDonald6, Hiroaki Ishida7, Hans J. Vogel6,7, Sharif Almutiri5,8, Ann Logan5, Stefan Kreida9, Tamim Al-Jubair9, Julie Winkel Missel10, Pontus Gourdon10,11, Susanna Törnroth-Horsefield9, Matthew T. Conner12, Zubair Ahmed5, Alex C. Conner13, Roslyn M. Bill1
1School of Life & Health Sciences, Aston University, Aston Triangle, Birmingham, B4 7ET, UK
2Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
3Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA
4Department of Pharmacology, College of Pharmacy, University of Mosul, Mosul 41002, Iraq
5Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
6Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4Z6, Canada
7Department of Biological Sciences, University of Calgary, Calgary, AB T2N 4N1, Canada
8Department of Clinical Laboratory Science, College of Applied Medical Science, Shaqra University, Shaqra, Saudi Arabia
9Department of Biochemistry and Structural Biology, Lund University, PO Box 124, 221 00 Lund, Sweden
10Department of Biomedical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark
11Department of Experimental Medical Science, Lund University, PO Box 118, 221 00 Lund, Sweden
12School of Sciences, Research Institute in Healthcare Science, University of Wolverhampton, Wolverhampton WV1 1LY, UK
13Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK

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