Autocrine growth factors and leukaemic haemopoiesis

Sieff, 1986, Haemopoietic growth factors, Journal of Clinical Investigation, 79, 1549, 10.1172/JCI112988 McCulloch, 1981, Blast cells in acute myeloblastic leukemia: a model, Blood Cells, 7, 63 Buick, 1977, Colony assay for proliferative blast progenitor cells circulating in myeloblastic leukemia, Lancet, 1, 862, 10.1016/S0140-6736(77)92818-5 Buick, 1979, Self-renewal in culture of proliferative blast progenitor cells in acute myeloblastic leukemia, Blood, 54, 65, 10.1182/blood.V54.1.95.95 Nara, 1985, The proliferation in suspension of the progenitors of the blast cells in acute myeloblastic leukaemia, Blood, 65, 1484, 10.1182/blood.V65.6.1484.bloodjournal6561484 Sabbath, 1985, Heterogeneity of clonogenic cells in acute myeloblastic leukemia, Journal of Clinical Investigation, 75, 746, 10.1172/JCI111756 Griffin, 1986, Clonogenic cells in acute myeloblastic leukemia, Blood, 68, 1185, 10.1182/blood.V68.6.1185.1185 Andrews, 1988, Monoclonal antibody 12-8 recognises a 125 kd molecule present on both unipotent multipotent hematopoietic colony-forming cells and their precursors, Blood, 67, 842, 10.1182/blood.V67.3.842.842 Silvestri, 1992, CD34 expression of acute myeloid leukemia—colony forming cells, International Journal of Cell Cloning, 10, 198 Bradbury, 1992, Role of autocrine and paracrine production of granulocyte-macrophage colony stimulating factor and interleukin-1 β in the autonomous growth of acute myeloblastic leukaemia cells—studies using purified CD34+ cells, Leukemia, 6, 652 Young, 1986, Autocrine secretion of GM-CSF in acute myeloblastic leukemia, Blood, 68, 1178, 10.1182/blood.V68.5.1178.1178 Reilly, 1989, Heterogeneous mechanisms of autocrine growth of AML blasts, British Journal of Haematology, 72, 363, 10.1111/j.1365-2141.1989.tb07717.x Murohashi, 1989, Autocrine growth mechanisms of the progenitors of blast cells in acute myeloblastic leukemia, Blood, 74, 35, 10.1182/blood.V74.1.35.35 Delwel, 1988, Growth regulation of human acute myeloid leukemia: Effects of five recombinant hematopoietic factors in a serum free culture system, Blood, 72, 1944, 10.1182/blood.V72.6.1944.1944 Reilly, 1988, The role of cell contact and autostimulatory soluble factors in the proliferation of blast cells in acute myeloblastic leukaemia, Leukemia, 3, 145 Hoang, 1986, Effects of recombinant GM-CSF on the blast cells of acute myeloblastic leukemia, Blood, 68, 313, 10.1182/blood.V68.1.313.313 Vellenga, 1987, Effects of recombinant IL-3, GM-CSF and G-CSF on the proliferation of leukemic clonogenic cells in short-term and long-term cultures, Leukemia, 1, 584 Miyauchi, 1987, The effects of three recombinant growth factors, IL-3, GM-CSF and G-CSF, on the blast cells of acute myeloblastic leukemia maintained in short-term suspension culture, Blood, 70, 657, 10.1182/blood.V70.3.657.657 Delwel, 1987, Human recombinant multilineage colony stimulating factor (interleukin-3): Stimulator of acute myelocytic progenitor cells, Blood, 70, 333, 10.1182/blood.V70.1.333.333 Kelleher, 1987, Synergism between recombinant growth factors, GM-CSF and G-CSF acting on the blast cells of acute myeloblastic leukemia, Blood, 69, 1498, 10.1182/blood.V69.5.1498.1498 Mochizuki, 1987, Interleukin-1 regulates hematopoietic activity, a role previously ascribed to hematopoietic activity, a role ascribed to hemopoietic-1, 84, 5267 Ikebuchi, 1987, Interleukin-6 enhancement of interleukin-3 dependent proliferation of multipotential hemopoietic precursors, 84, 9035 Hoang, 1988, Interleukin-1 enhances growth factor-dependent proliferation of the clonogenic cells in acute myeloblastic leukaemia and of normal primitive hemopoietic precursors, Journal of Experimental Medicine, 168, 463, 10.1084/jem.168.2.463 Hoang, 1988, Interleukin-6 enhances growth-factor dependent proliferation of blast cells of acute myeloblastic leukemia, Blood, 72, 823, 10.1182/blood.V72.2.823.823 Hoang, 1989, Tumour necrosis factor-α stimulates the growth of the clonogenic cells of acute myeloblastic leukemia in synergy with granulocyte-macrophage colony stimulating factor, Journal of Experimental Medicine, 170, 15, 10.1084/jem.170.1.15 Elbas, 1991, Tumour necrosis factor regulates the expression of granulocyte-macrophage colony-stimulating factor and interleukin-3 receptors, Blood, 77, 989, 10.1182/blood.V77.5.989.989 Budel, 1990, Common binding structure for granulocyte/macrophage colony-stimulating factor and interleukin-3 on human acute myeloid leukemia cells and monocytes, Blood, 75, 1439, 10.1182/blood.V75.7.1439.1439 Salem, 1990, Modulation of colony-stimulating factor (CSF) dependent growth of acute myeloid leukemia cells by tumour necrosis factor, Leukemia, 4, 37 Elbaz, 1991, Tumour necrosis factor down-regulates granulocyte-colony stimulating factor receptor expression on human acute myeloid leukemia cells and granulocytes, Journal of Clinical Investigation, 87, 838, 10.1172/JCI115087 Caux, 1990, Tumour necrosis factor-alpha strongly potentiates interleukin-3 and granulocyte-macrophage colony stimulating factor induced proliferation of human CD34+ hematopoietic progenitors, Blood, 75, 2292, 10.1182/blood.V75.12.2292.2292 Sporn, 1985, Autocrine growth factors and cancer, Nature, 313, 745, 10.1038/313745a0 Browder, 1989, Private and public autocrine loops in neoplastic cells, Cancer Cells, 1, 9 Keating, 1988, Autocrine stimulation on intracellular PDGF receptors in v-sis-transformed cells, Science, 239, 914, 10.1126/science.2829358 Dexter, 1980, Growth of factor-dependent hemopoietic precursor cell lines, Journal of Experimental Medicine, 152, 1047, 10.1084/jem.152.4.1036 Lang, 1985, Expression of a hemopoietic growth factor cDNA in a factor dependent cell line results in autonomous growth and tumourigenicity, Cell, 43, 531, 10.1016/0092-8674(85)90182-5 Hapel, 1986, Generation of an autocrine leukemia using a retroviral expression vector carrying the interleukin-3 gene, Lymphokine Research, 5, 249 Dunbar, 1989, COOH-terminal-modified interleukin-3 is retained intracellularly and stimulates autocrine growth, Science, 245, 1493, 10.1126/science.2789432 Metcalf, 1987, The in vitro behaviour of hematopoietic cells transformed by polyoma middle T. antigen parallels that of primary human myeloid leukemic cells, EMBO Journal, 6, 3703, 10.1002/j.1460-2075.1987.tb02704.x Duhrsen, 1988, In vitro growth patterns and autocrine production of hemopoietic colony stimulatory factors; Analysis of Leukemic populations arising in irradiated mice from cells of an injected factor-dependent continuous cell line, Leukemia, 2, 334 Dunn, 1990, Contributions of autocrine and non-autocrine mechanisms of tumorigenicity in a murine model for leukaemia, 145 Johnson, 1989, A lethal myeloproliferative syndrome in mice transplanted with bone marrow cells infected with a retrovirus expressing granulocyte-macrophage colony stimulatory factor, EMBO Journal, 8, 441, 10.1002/j.1460-2075.1989.tb03396.x Larry, 1987, Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness and a fatal syndrome of tissue damage, Cell, 51, 675, 10.1016/0092-8674(87)90136-X Young, 1987, Constitutive expression of the granulocyte-macrophage colony stimulating factor gene in acute myeloblastic leukemia, Journal of Clinical Investigation, 79, 200, 10.1172/JCI112769 Oster, 1989, Participation of cytokines interleukin-6, tumour necrosis factor-alpha and interleukin-1-beta secreted by acute myelogenous leukemia blasts in autocrine and paracrine leukemia growth control, Journal of Clinical Investigation, 84, 451, 10.1172/JCI114186 Cheng, 1988, Structure and expression of genes of GM-CSF and G-CSF in blast cells from patients with acute myeloblastic leukemia, Blood, 71, 35, 10.1182/blood.V71.1.204.204 Griffin, 1987, Secretion of Interleukin-1 by acute myeloblastic leukemia cells in vitro induces endothelial cells to secrete colony stimulating factors, Blood, 70, 1218, 10.1182/blood.V70.4.1218.1218 Young, 1988, In vitro expression of colony stimulating factor genes by human acute myeloblastic leukemia cells, Experimental Haematology, 16, 378 Kaufman, 1988, Enhanced expression of granulocytes-macrophage colony stimulating factor genein acute myeloblastic leukemia cells following in vitro blast cell enrichment, Blood, 72, 1329, 10.1182/blood.V72.4.1329.1329 Van der Schoot, 1989, Interleukin-6 and interleukin-1 production in acute leukemia with monocytoid differentiation, Blood, 74, 2081, 10.1182/blood.V74.6.2081.2081 Falcinelli, 1991, Activation of the granulocyte-monocyte colony stimulating factor gene in acute myeloid leukemia cells is not related to gene rearrangement, Leukemia Research, 15, 957, 10.1016/0145-2126(91)90173-Q Rodriguez-Cimadevilla, 1990, Co-ordinate secretion of interleukin-1β and granulocyte macrophage colony stimulating factor by the blast cells of acute myeloblastic leukemia: Role of Interleukin-1 as an endogenous inducer, Blood, 76, 1481, 10.1182/blood.V76.8.1481.1481 Rogers, 1991, Mechanism of autonomous growth in acute myeloid leukemia cells. Evidence of intracellular and extracellular autocrine and paracrine loops, Blood, 78, 1053 Wang, 1988, Expression of the CSF-1 gene in the blast cells of acute myeloblastic leukemia: Association with reduced growth capacity, Journal of Cellular Physiology, 135, 133, 10.1002/jcp.1041350119 Mitjavila, 1991, Autocrine stimulation by erythropoietin and autonomous growth of human erythroid leukaemia cells in vitro, Journal of Clinical Investigation, 88, 789, 10.1172/JCI115378 Bagby, 1989, Interleukin-1 and haematopoiesis, Blood Reviews, 3, 152, 10.1016/0268-960X(89)90012-X Bradbury, 1990, Interleukin-1 is one factor which regulates the autocrine production of GM-CSF by blast cells of acute myeloblastic leukaemia, British Journal of Haematology, 76, 488, 10.1111/j.1365-2141.1990.tb07905.x Delwel, 1989, Interleukin-1 stimulates proliferation of acute myeloblastic leukemia cells by induction of granulocyte-macrophage colony-stimulating factor release, Blood, 74, 586, 10.1182/blood.V74.2.586.586 Murohashi, 1990, Mechanism of action of interleukin-1 on the progenitors of blast cells in acute myeloblastic leukemia, Experimental Haematology, 18, 133 Brach, 1990, Interleukin-6 (IL-6) as an intermediate in IL-1-induced proliferation of leukemic human megakaryoblasts, Blood, 76, 1972, 10.1182/blood.V76.10.1972.1972 Sakai, 1987, Autocrine stimulation of Interleukin 1β in acute myelogenous leukemia cells, Journal of Experimental Medicine, 166, 1597, 10.1084/jem.166.5.1597 Cozzolino, 1989, Interleukin-1 as an autocrine growth factor for acute myeloid leukemia cells, 86, 2369 Nakamura, 1990, Demonstration of Interleukin-1β transcripts in acute myeloblastic leukemia cells by in situ hybridisation, Leukemia, 44, 466 Bradbury, 1990, Endogenous interleukin-1 can regulate autonomous growth of acute myeloblastic leukemia and by inducing autocrine secretion of GM-CSF, Leukemia, 4, 44 Yamato, 1989, Regulation of IL-1 mRNA in human fibroblast, Journal of Cellular Physiology, 139, 610, 10.1002/jcp.1041390322 Yamato, 1989, Granulocyte-macrophage colony-stimulating factor: Signals for its mRNA accumulation, Blood, 74, 1314, 10.1182/blood.V74.4.1314.1314 Shaw, 1986, A conserved AU sequence from the 31 untranslated region of GM-CSF mRNA mediates selective mRNA degradation, Cell, 46, 659, 10.1016/0092-8674(86)90341-7 Demetri, 1989, Expression of ras oncogenes in cultured human cells alters the transcriptional and post-transcriptional regulation of cytokine genes, Journal of Clinical Investigation, 86, 1261, 10.1172/JCI114833 Ross, 1991, Cytokine messenger RNA stability in enhanced in tumour cells, Blood, 77, 1787, 10.1182/blood.V77.8.1787.1787 Ernst, 1989, Colony-stimulating factor gene expression in human acute myeloblastic leukemia cells is post-transcriptionally regulated, Leukemia, 3, 620 Bot, 1990, Interleukin-1α also induces granulocyte-macrophage colony-stimulating factor in immature normal bone marrow cells, Blood, 76, 307, 10.1182/blood.V76.2.307.307 Dinarello, 1991, Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro, Immunology Today, 12, 404, 10.1016/0167-5699(91)90142-G Rambaldi, 1991, Modulation of cell proliferation and cytokine production in acute myeloblastic leukemia by interleukin-1 receptor antagonist and lack of its expression by leukemic cells, Blood, 78, 3248, 10.1182/blood.V78.12.3248.3248 Estrov, 1992, Inhibition of acute myelogenous leukemia blast proliferation by interleukin-1 (IL-1) receptor antagonist and soluble IL-1 receptors, Blood, 79, 1938, 10.1182/blood.V79.8.1938.1938 Henderson, 1992, Therapeutic potential of cytokine manipulation, Trends in Pharmaceutical Science, 13, 145, 10.1016/0165-6147(92)90052-8