Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery of benzimidazole 5-carboxylic amide derivatives with low-nanomolar potency

Bioorganic & Medicinal Chemistry Letters - Tập 14 - Trang 967-971 - 2004
Pierre L Beaulieu1, Michael Bös1, Yves Bousquet1, Patrick DeRoy1, Gulrez Fazal1, Jean Gauthier1, James Gillard1, Sylvie Goulet1, Ginette McKercher2, Marc-André Poupart1, Serge Valois1, George Kukolj2
1Department of Chemistry, Boehringer Ingelheim (Canada) Ltd, Research and Development, 2100 Cunard Street, Laval (Québec), Canada H7S 2G5
2Department of Biological Sciences, Boehringer Ingelheim (Canada) Ltd, Research and Development, 2100 Cunard Street, Laval (Québec), Canada H7S 2G5

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