PARP-1 activation leads to cytosolic accumulation of TDP-43 in neurons

Neurochemistry International - Tập 148 - Trang 105077 - 2021
Joshua M. Marcus1, Mohammed I. Hossain1, Jean-Philippe Gagné2, Guy G. Poirier2, Lori L. McMahon3, Rita M. Cowell3,4, Shaida A. Andrabi1,5
1Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
2Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University, Québec City, QC, G1V 0A6, Canada
3Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA
4Department of Neuroscience, Biological Sciences Division, Southern Research, Birmingham, AL, 35205, USA
5Department of Neurology, University of Alabama at Birmingham, Birmingham, AL 35294, USA